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Assessment of the risk for the progression of occupational diseases under exposure to harmful occupational factor 职业性有害因素暴露下职业病发展风险评估
Q4 Medicine Pub Date : 2023-10-09 DOI: 10.47470/0016-9900-2023-102-8-790-795
Otari G. Khurtsilava, Ivan V. Boiko, Sergei V. Greben’kov, Alexander N. Nikanov, Natalia N. Loginova
Introduction. Currently, there are no clear definitions of unacceptable worker health risk criteria, which are related to incidence indicators of further development of already formed occupational diseases. It refers to cases when a worker with a diagnosed occupational disease continues to work under harmful occupational factor exposure which has caused occupational pathology development. Materials and methods. According to the archive materials of occupational pathology clinics, risk assessment of further development of occupational disease caused by physical overload, in a group of patients with diagnosed occupational disease, being under follow-up and proceeding their working activity, was carried out Results. Regulatory documents in the field of occupational fitness expertise, currently effective in Russian Federation, provide the possibility of continuing work under the same conditions for patients with diagnosed occupational disease. However, such policy results in the loss of right to get payment for medical rehabilitation among occupational disease patients. Based on epidemiological survey findings, procedural approaches to assessing the risk of occupational disease deterioration, in case a patient proceeding to work under the same conditions of exposure to adverse occupational factors, as unacceptable, are considered. Limitations. In patients with occupational pathology of a different profile, working in other conditions, other results may be obtained on the risk of disease progression with continued work. Conclusions. It is necessary to create and implement an official uniform system for qualifying risk for the development of occupational pathology in patients going on to work in adverse conditions. At the first stage an assessment of risk for the development of these health disturbances, based on the value of occupational morbidity rate index, which takes into account both, the incidence of negative effect on worker’s health, and the severity of health disturbances, can be used.
介绍。目前,对不可接受的工人健康风险标准没有明确的定义,这些标准与已经形成的职业病进一步发展的发病率指标有关。指经诊断患有职业病的劳动者继续接触有害职业因素,并发生职业病理发展的情况。材料和方法。根据职业病理门诊档案资料,对一组已确诊职业病、正在接受随访并继续工作活动的患者进行体能超负荷导致职业病进一步发展的风险评估 结果。目前在俄罗斯联邦有效的职业健身专业知识领域的规范性文件为诊断为职业病的患者提供了在相同条件下继续工作的可能性。然而,这种政策导致职业病患者丧失获得医疗康复费用的权利。根据流行病学调查结果,如果病人在接触不利职业因素的相同条件下继续工作,则认为评估职业病恶化风险的程序性方法是不可接受的。& # x0D;的局限性。在具有不同职业病理特征、在其他条件下工作的患者中,关于继续工作的疾病进展风险可能会得到其他结果。 结论。有必要建立和实施一个官方的统一系统,以确定在不利条件下继续工作的患者的职业病理学发展的风险。在第一阶段,可以根据职业发病率指数的值对这些健康问题的风险进行评估,该指数考虑到对工人健康产生负面影响的发生率和健康问题的严重程度。
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 Materials and methods. According to the archive materials of occupational pathology clinics, risk assessment of further development of occupational disease caused by physical overload, in a group of patients with diagnosed occupational disease, being under follow-up and proceeding their working activity, was carried out
 Results. Regulatory documents in the field of occupational fitness expertise, currently effective in Russian Federation, provide the possibility of continuing work under the same conditions for patients with diagnosed occupational disease. However, such policy results in the loss of right to get payment for medical rehabilitation among occupational disease patients. Based on epidemiological survey findings, procedural approaches to assessing the risk of occupational disease deterioration, in case a patient proceeding to work under the same conditions of exposure to adverse occupational factors, as unacceptable, are considered. 
 Limitations. In patients with occupational pathology of a different profile, working in other conditions, other results may be obtained on the risk of disease progression with continued work.
 Conclusions. It is necessary to create and implement an official uniform system for qualifying risk for the development of occupational pathology in patients going on to work in adverse conditions. At the first stage an assessment of risk for the development of these health disturbances, based on the value of occupational morbidity rate index, which takes into account both, the incidence of negative effect on worker’s health, and the severity of health disturbances, can be used.","PeriodicalId":12550,"journal":{"name":"Gigiena i sanitariia","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135148705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficiency of reduction of noise from railway transport by acoustic screens 用隔音屏障降低铁路运输噪音的效率
Q4 Medicine Pub Date : 2023-10-09 DOI: 10.47470/0016-9900-2023-102-8-764-767
Olga I. Kopytenkova, Tatiana A. Afanasyeva
Introduction. The strategy for the development of transport infrastructure in Russia involves the construction of railway tracks, including for high-speed traffic. The noise created by rail transport creates uncomfortable living conditions for citizens. One of the most common methods of noise reduction in the way of its propagation is the installation of acoustic screens. The purpose of the work. To evaluate the effectiveness of acoustic screens used to reduce noise from linear objects of railway transport. Materials and methods. To evaluate the effectiveness of acoustic screens in the reverberation chamber, a study of six types of materials most commonly used for their construction was conducted. Experimental studies calculations were carried out in accordance with the requirements of current regulatory and technical documentation. Results. Experimental studies have shown air noise isolation levels to vary from 27 dBA to 44 dBA. In real conditions, the long-wave part of the noise spectrum of railway transport bends around the screen, forming an acoustic shadow. The calculated acoustic shadow from the AE for non-electrified tracks is 45.95 m from the screen, for electrified tracks – 40.56 m. The efficiency of acoustic screens was shown to decrease with increasing train speed. Limitations. The limitations are determined by the value of the calculated uncertainty indicator obtained by analyzing the results of acoustic measurements. Conclusion. The use of acoustic screens as the main noise protection measure has little prospect in newly built-up areas with high-rise residential and public buildings, and in the conditions of the prospect of intensive development of high-speed rail traffic. The procedure for establishing the estimated size of the distance from the railway tracks, ensuring compliance with the requirements of sanitary and epidemiological well-being, needs a clear regulation of the list and quality of the initial data, taking into account the peculiarities of the structure of the track and the management of railway traffic.
介绍。俄罗斯交通基础设施发展战略涉及铁路轨道建设,包括高速交通。铁路运输产生的噪音给市民带来了不舒适的生活条件。在其传播方式中,最常见的降噪方法之一是安装隔音屏障。& # x0D;工作的目的。评价声屏用于降低铁路运输线性物体噪声的有效性。 材料和方法。为了评估混响室中声屏的有效性,对六种最常用的材料进行了研究。实验研究计算是按照现行法规和技术文件的要求进行的。 结果。实验研究表明,空气噪声隔离级别从27 dBA到44 dBA不等。在实际情况下,铁路运输噪声频谱的长波部分在屏幕周围弯曲,形成声阴影。计算得到的非电气化轨道声发射阴影距屏幕45.95 m,电气化轨道声发射阴影距屏幕40.56 m。声屏的效率随列车速度的增加而降低。& # x0D;的局限性。通过对声学测量结果的分析,计算出的不确定度指标值决定了限制。 结论。在新建的高层住宅和公共建筑较多的地区,以及高速铁路交通集约发展的条件下,采用隔声屏作为主要的噪声防护措施的前景不大。在确定距离铁路轨道的估计长度,确保符合卫生和流行病的要求的程序中,需要明确规定清单和质量 在初始数据的基础上,考虑到轨道结构和铁路交通管理的特殊性。
{"title":"Efficiency of reduction of noise from railway transport by acoustic screens","authors":"Olga I. Kopytenkova, Tatiana A. Afanasyeva","doi":"10.47470/0016-9900-2023-102-8-764-767","DOIUrl":"https://doi.org/10.47470/0016-9900-2023-102-8-764-767","url":null,"abstract":"Introduction. The strategy for the development of transport infrastructure in Russia involves the construction of railway tracks, including for high-speed traffic. The noise created by rail transport creates uncomfortable living conditions for citizens. One of the most common methods of noise reduction in the way of its propagation is the installation of acoustic screens. 
 The purpose of the work. To evaluate the effectiveness of acoustic screens used to reduce noise from linear objects of railway transport.
 Materials and methods. To evaluate the effectiveness of acoustic screens in the reverberation chamber, a study of six types of materials most commonly used for their construction was conducted. Experimental studies calculations were carried out in accordance with the requirements of current regulatory and technical documentation.
 Results. Experimental studies have shown air noise isolation levels to vary from 27 dBA to 44 dBA. In real conditions, the long-wave part of the noise spectrum of railway transport bends around the screen, forming an acoustic shadow. The calculated acoustic shadow from the AE for non-electrified tracks is 45.95 m from the screen, for electrified tracks – 40.56 m. The efficiency of acoustic screens was shown to decrease with increasing train speed. 
 Limitations. The limitations are determined by the value of the calculated uncertainty indicator obtained by analyzing the results of acoustic measurements.
 Conclusion. The use of acoustic screens as the main noise protection measure has little prospect in newly built-up areas with high-rise residential and public buildings, and in the conditions of the prospect of intensive development of high-speed rail traffic. The procedure for establishing the estimated size of the distance from the railway tracks, ensuring compliance with the requirements of sanitary and epidemiological well-being, needs a clear regulation of the list and quality 
 of the initial data, taking into account the peculiarities of the structure of the track and the management of railway traffic.","PeriodicalId":12550,"journal":{"name":"Gigiena i sanitariia","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135149646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of CYP1A2 gene polymorphism (rs762551) with the risk of breast cancer and miscarriage of the first pregnancy CYP1A2基因多态性(rs762551)与风险的关系
乳腺癌和第一次怀孕流产的风险
Q4 Medicine Pub Date : 2023-10-09 DOI: 10.47470/0016-9900-2023-102-8-848-852
Olga N. Gulyaeva, Anastasiуa S. Kazitskaya, Evgeniya V. Ulanova, Sergey V. Matoshin, Mariya V. Chifranova, Lyudmila V. Renge, Svetlana V. Shramko
Introduction. Missed pregnancy, as a rule, is caused by a combination of several factors. Exogenous factors can have a teratogenic effect, leading to the occurrence of mutations of varying severity. In such case at the early stages of embryogenesis, serious disturbances occur, leading to a halt in the pregnancy development. The system of their biotransformation is responsible for the elimination of xenobiotics from the body, the inadequate functioning of which increases the activity of mutagenesis, which may raise the risk of breast cancer. Materials and methods. One hundred thirty four women were examined. The first group included 63 women, 28 of them were diagnosed with fetal egg death in primigravida young women, in 35 women the first pregnancy ended with physiological childbirth. The second group included 71 woman, 33 of them were diagnosed with a malignant breast neoplasm, 38 had no suspicion of breast cancer (BC) according to the results of mammography. Polymorphisms of the CYP1A2*1F gene of the xenobiotic biotransformation system in these groups were determined by polymerase chain reaction. Results. In the group of women with a missed first pregnancy, a statistically reliable association of a high risk of the fetal egg death with the A/A CYP1A2*1F genotype and resistance to this pathology in the case of the C/A CYP1A2*1F polymorphism was revealed. In the group of BC women, the association of a high risk of developing a malignant neoplasm with the A/A CYP1A2*1F genotype and resistance to the development of the disease in the presence of C/A CYP1A2*1F polymorphism was shown. Limitations. The study was limited by the number of samples, there is no data on polymorphisms of the BRCA-1, BRCA-2 genes. Conclusion. The results obtained will allow not only adjusting the tactics of pregnancy management in women with a high risk of the fetal egg death or the selection of pharmacological drugs in the treatment of BC under the conditions of serious environmental stress, but also developing preventive measures to reduce the risk of these pathologies.
介绍。通常,漏孕是由多种因素共同造成的。外源因素可具有致畸作用,导致不同程度突变的发生。在这种情况下,在胚胎发生的早期阶段,发生严重的干扰,导致妊娠发育停止。它们的生物转化系统负责消除体内的外来生物,其功能不足会增加诱变的活性,这可能会增加患乳腺癌的风险。材料和方法。134名妇女接受了检查。第一组包括63名妇女,其中28名初产妇被诊断为胎卵死亡,35名妇女首次怀孕以生理分娩结束。第二组71名妇女,其中33名诊断为乳腺恶性肿瘤,38名根据乳房x光检查结果未怀疑为乳腺癌(BC)。采用聚合酶链反应测定各组异种生物转化系统CYP1A2*1F基因多态性。 结果。在首次妊娠未成功的妇女组中,揭示了a / a CYP1A2*1F基因型和C/ a CYP1A2*1F基因型对这种病理的耐药性与胎卵死亡的高风险有统计学可靠的关联。在BC组女性中,a / a CYP1A2*1F基因型和C/ a CYP1A2*1F多态性与恶性肿瘤发展的高风险相关。 的局限性。受样本数量的限制,没有BRCA-1、BRCA-2基因多态性的数据。 结论。所获得的结果不仅可以调整胎卵死亡高风险妇女的妊娠管理策略或在严重环境应激条件下治疗BC的药物选择,而且还可以制定预防措施以降低这些病理的风险。
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 of breast cancer and miscarriage of the first pregnancy","authors":"Olga N. Gulyaeva, Anastasiуa S. Kazitskaya, Evgeniya V. Ulanova, Sergey V. Matoshin, Mariya V. Chifranova, Lyudmila V. Renge, Svetlana V. Shramko","doi":"10.47470/0016-9900-2023-102-8-848-852","DOIUrl":"https://doi.org/10.47470/0016-9900-2023-102-8-848-852","url":null,"abstract":"Introduction. Missed pregnancy, as a rule, is caused by a combination of several factors. Exogenous factors can have a teratogenic effect, leading to the occurrence of mutations of varying severity. In such case at the early stages of embryogenesis, serious disturbances occur, leading to a halt in the pregnancy development. The system of their biotransformation is responsible for the elimination of xenobiotics from the body, the inadequate functioning of which increases the activity of mutagenesis, which may raise the risk of breast cancer.
 Materials and methods. One hundred thirty four women were examined. The first group included 63 women, 28 of them were diagnosed with fetal egg death in primigravida young women, in 35 women the first pregnancy ended with physiological childbirth. The second group included 71 woman, 33 of them were diagnosed with a malignant breast neoplasm, 38 had no suspicion of breast cancer (BC) according to the results of mammography. Polymorphisms of the CYP1A2*1F gene of the xenobiotic biotransformation system in these groups were determined by polymerase chain reaction.
 Results. In the group of women with a missed first pregnancy, a statistically reliable association of a high risk of the fetal egg death with the A/A CYP1A2*1F genotype and resistance to this pathology in the case of the C/A CYP1A2*1F polymorphism was revealed. In the group of BC women, the association of a high risk of developing a malignant neoplasm with the A/A CYP1A2*1F genotype and resistance to the development of the disease in the presence of C/A CYP1A2*1F polymorphism was shown.
 Limitations. The study was limited by the number of samples, there is no data on polymorphisms of the BRCA-1, BRCA-2 genes.
 Conclusion. The results obtained will allow not only adjusting the tactics of pregnancy management in women with a high risk of the fetal egg death or the selection of pharmacological drugs in the treatment of BC under the conditions of serious environmental stress, but also developing preventive measures to reduce the risk of these pathologies.","PeriodicalId":12550,"journal":{"name":"Gigiena i sanitariia","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135149651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Course and outcomes of pregnancy in women working in cold climate regions 在寒冷气候地区工作的妇女怀孕的过程和结果
Q4 Medicine Pub Date : 2023-10-09 DOI: 10.47470/0016-9900-2023-102-8-775-782
Daria S. Borisova, Valerii P. Chashchin, Alexandr N. Nikanov, Nikolay N. Petruhin, Alexander A. Kovshov
Introduction. The causal association of infertility risk, complicated course and outcomes of pregnancy, as well as maternal, perinatal and neonatal mortality, with the lag-effects of cooling meteorological factors, is the least studied problem in occupational health. The national legal acts regulating occupational health issues do not classify the performance of labour operations in a low-temperature environment as work hazardous to reproductive health. The purpose of the study. Based on an assessment of the likelihood of pregnancy complications in women engaged in labour operations in open areas or in unheated workrooms in cold climate regions, to develop recommendations for improving state regulation measures aimed at maintaining reproductive health and reducing reproductive losses in female workers employed in these regions. Materials and methods. A questionnaire survey was conducted among two hundred forty six female workers of childbearing age performing labour operations in an open area or in unheated workrooms. As methods of statistical processing, conventional statistical methods were used using a personal computer with installed Microsoft software products (Microsoft Excel 2013) and application software (Statistica v.12). Results. Performing labour operations in a cold environment is associated with a statistically significant higher prevalence of pregnancy complications in female workers engaged in cold season labour operations in open areas or unheated workrooms as long as from 1 to -3 hours, and especially more than 3 hours per work shift. Among the population living in the region of the Pechora coal basin, the risks of crisis phenomena in demographic development remain, which are mainly due to an increase in the frequency of pregnancy complications and, above all, due to high level of fetal and infant losses. Conclusion. To solve one of the main tasks of national security to prevent further depopulation of the Arctic regions, in addition to socio-economic measures to preserve the population and increase the total fertility rate, it is necessary to improve the regulatory legal acts focused on the protection of the reproductive health of women working in a cold environment. Limitations. The period of the study is from 2015 to 2019. The number of respondents was 246 women experienced one or more pregnancies when worked in the cold workplaces.
介绍。不孕风险、复杂的妊娠过程和结局以及孕产妇、围产期和新生儿死亡率与降温气象因素的滞后效应之间的因果关系,是职业卫生领域研究最少的问题。规范职业健康问题的国家法律没有将低温环境下的劳动作业归类为危害生殖健康的工作。& # x0D;研究的目的。根据对在开放地区或在寒冷气候地区没有暖气的工作室内从事劳动作业的妇女发生妊娠并发症可能性的评估,制定建议,以改进旨在维护这些地区雇用的女工的生殖健康和减少生殖损失的国家管理措施。& # x0D;材料和方法。对246名育龄女工进行了问卷调查,这些女工在开放区域或没有暖气的工作室内进行劳动作业。统计处理方法采用常规统计方法,使用个人电脑,安装微软软件产品(Microsoft Excel 2013)和应用软件(Statistica v.12)。& # x0D;结果。在寒冷的环境中进行劳动作业,在露天或没有暖气的工作室内进行寒冷季节劳动作业的女工怀孕并发症的发生率在统计上显著增加,每次工作时间长达1至3小时,特别是超过3小时。在生活在佩霍拉煤田地区的人口中,人口发展中危机现象的危险仍然存在,这主要是由于妊娠并发症的频率增加,尤其是由于胎儿和婴儿的死亡率很高。& # x0D;结论。为了解决防止北极地区人口进一步减少这一国家安全的主要任务之一,除了采取社会经济措施以保护人口和提高总生育率外,还必须改进以保护在寒冷环境中工作的妇女的生殖健康为重点的规范性法律行为。& # x0D;的局限性。研究时间为2015年至2019年。有246名女性在寒冷的工作场所工作时怀孕一次或多次。
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 The purpose of the study. Based on an assessment of the likelihood of pregnancy complications in women engaged in labour operations in open areas or in unheated workrooms in cold climate regions, to develop recommendations for improving state regulation measures aimed at maintaining reproductive health and reducing reproductive losses in female workers employed in these regions. 
 Materials and methods. A questionnaire survey was conducted among two hundred forty six female workers of childbearing age performing labour operations in an open area or in unheated workrooms. As methods of statistical processing, conventional statistical methods were used using a personal computer with installed Microsoft software products (Microsoft Excel 2013) and application software (Statistica v.12). 
 Results. Performing labour operations in a cold environment is associated with a statistically significant higher prevalence of pregnancy complications in female workers engaged in cold season labour operations in open areas or unheated workrooms as long as from 1 to -3 hours, and especially more than 3 hours per work shift. Among the population living in the region of the Pechora coal basin, the risks of crisis phenomena in demographic development remain, which are mainly due to an increase in the frequency of pregnancy complications and, above all, due to high level of fetal and infant losses. 
 Conclusion. To solve one of the main tasks of national security to prevent further depopulation of the Arctic regions, in addition to socio-economic measures to preserve the population and increase the total fertility rate, it is necessary to improve the regulatory legal acts focused on the protection of the reproductive health of women working in a cold environment. 
 Limitations. The period of the study is from 2015 to 2019. The number of respondents was 246 women experienced one or more pregnancies when worked in the cold workplaces.","PeriodicalId":12550,"journal":{"name":"Gigiena i sanitariia","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135149516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Heterogeneity of the modified SIR-model parameters of waves of COVID-19 epidemic process in the Russian Federation 俄罗斯联邦新冠肺炎流行过程修正sir模型参数的异质性
Q4 Medicine Pub Date : 2023-10-09 DOI: 10.47470/0016-9900-2023-102-8-740-749
Anna Yu. Popova, Nina V. Zaitseva, Vadim B. Alekseev, Aleksandr N. Letyushev, Dmitry A. Kiryanov, Svetlana V. Kleyn, Marat R. Kamaltdinov, Maxim V. Glukhikh
Introduction. The work is dedicated to the parameterization of the COVID-19 epidemic process, taking into account the specifics of the Russian Federation regions. Purpose of study is the analysis of the spatio-temporal distribution of heterogeneous indicators of the spread of COVID-19 based on the formalization and parametrization of waves of the epidemic process, bearing in mind regional specifics. Materials and methods. SIR (+L) model as a modification of the classic SIR model, reflecting the trend in the transition of the susceptible to the action of the virus (S – susceptible) population to the group of infected (I – infected), recovered (R – recovered) and the dead (L – letal) was used as a basic model of the epidemic process. Results. Time ranges of activation of the epidemic process in the regions of the Russian Federation, corresponding to waves of domination of certain strains of the virus, have been allocated on the basis of the analysis of time series COVID-19 morbidity with a week period of averaging. In total, starting from September 6, 2020 and ending on February 25, 2023, four epidemic waves have been allocated for each region. Analysis of SIR (+L) model parameters for each wave by regions of the Russian Federation made it possible to establish a number of characteristic trends and obtain interpretable directions of influence on the epidemic process individual stages, with the subsequent development of systemic strategic decisions on the preservation of population health and its level of safety at the regional and country-wide scale. Limitations. The presented modification of the SIR model (SIR (+L) model) is a significant simplification of the real epidemic process and does not allow describing a number of observed effects. Conclusion. Based on the results of the parametrization of the epidemic process, the main features and patterns of the spread of the COVID-19, the intensity of recovery and mortality were established. A further direction of research may be the complication of the epidemic process model, the addition of new parameters to it, taking into account the division of the population into gender and age groups, diseases by severity, grouping according to the territorial and social principle, and the identification of the latent morbidity.
介绍。考虑到俄罗斯联邦各地区的具体情况,这项工作致力于参数化COVID-19流行过程。& # x0D;研究目的是基于疫情过程波的形式化和参数化,考虑区域特点,分析COVID-19传播异质性指标的时空分布。 材料和方法。SIR (+L)模型作为对经典SIR模型的修正,反映了受病毒作用的易感人群(S -易感)向感染(I -感染)、恢复(R -恢复)和死亡(L -致命)群体过渡的趋势。 结果。根据对COVID-19发病率时间序列的分析,以一周为平均周期,在俄罗斯联邦各地区分配了流行病进程启动的时间范围,对应于某些病毒株的统治浪潮。从2020年9月6日到2023年2月25日,每个地区共划分了四波疫情。对俄罗斯联邦各地区每一波的SIR (+L)模型参数进行分析,可以确定若干特征趋势,并获得对流行病进程各个阶段的可解释的影响方向,随后制定关于在区域和全国范围内维护人口健康及其安全水平的系统战略决策。 的局限性。提出的SIR模型(SIR (+L)模型)的修正是对真实流行病过程的显著简化,并且不允许描述许多观察到的效应。结论。根据疫情过程参数化结果,确定了疫情传播、恢复强度和死亡率的主要特征和模式。进一步的研究方向可能是使流行病过程模型复杂化,为其增加新的参数,同时考虑到人口按性别和年龄组划分,按疾病严重程度划分,按地域和社会原则分组,以及确定潜在发病率。
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 Purpose of study is the analysis of the spatio-temporal distribution of heterogeneous indicators of the spread of COVID-19 based on the formalization and parametrization of waves of the epidemic process, bearing in mind regional specifics.
 Materials and methods. SIR (+L) model as a modification of the classic SIR model, reflecting the trend in the transition of the susceptible to the action of the virus (S – susceptible) population to the group of infected (I – infected), recovered (R – recovered) and the dead (L – letal) was used as a basic model of the epidemic process.
 Results. Time ranges of activation of the epidemic process in the regions of the Russian Federation, corresponding to waves of domination of certain strains of the virus, have been allocated on the basis of the analysis of time series COVID-19 morbidity with a week period of averaging. In total, starting from September 6, 2020 and ending on February 25, 2023, four epidemic waves have been allocated for each region. Analysis of SIR (+L) model parameters for each wave by regions of the Russian Federation made it possible to establish a number of characteristic trends and obtain interpretable directions of influence on the epidemic process individual stages, with the subsequent development of systemic strategic decisions on the preservation of population health and its level of safety at the regional and country-wide scale.
 Limitations. The presented modification of the SIR model (SIR (+L) model) is a significant simplification of the real epidemic process and does not allow describing a number of observed effects.
 Conclusion. Based on the results of the parametrization of the epidemic process, the main features and patterns of the spread of the COVID-19, the intensity of recovery and mortality were established. A further direction of research may be the complication of the epidemic process model, the addition of new parameters to it, taking into account the division of the population into gender and age groups, diseases by severity, grouping according to the territorial and social principle, and the identification of the latent morbidity.","PeriodicalId":12550,"journal":{"name":"Gigiena i sanitariia","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135149517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Morbidity of aircraft workers with temporary disability 飞机工人暂时残疾的发病率
Q4 Medicine Pub Date : 2023-10-09 DOI: 10.47470/0016-9900-2023-102-8-836-841
Olga A. Molchanova, Olga G. Bogdanova, Vladimir A. Pankov, Mikhail Yu. Itygilov
Introduction. Increasing and expanding the volume of aircraft production causes an additional burden on the health of employees involved in the production process and, accordingly, the risks of occurrence of both occupational and production-related diseases increase. Aim of the study is to assess the occupational health risks for employees in main occupations of the aircraft building enterprise in terms of the incidence of temporary disability. Materials and methods. The incidence with temporary disability (ITD) of employees of the main occupations of the aircraft building enterprise (ABE) for the period 2017–2021 were studied using methods of descriptive statistics. Significance level determined at p < 0.05. Results. During the analyzed period there was the gain in ITD among working ABE was shown to be in all study groups. Average indicators for the number of cases, days of disability in working ABE in the main groups are higher of similar indicators in the control groups. During the qualitative assessment of ITD, average indicators for employees of noise and vibration-hazardous occupations in terms of the number of cases and days of disability were found to be very high, for those working in contact with chemicals – high. Limitations. The results of this study are due to the general morbidity, excluding occupational, which requires further research. Conclusion. In the current conditions of industrial development of the AВE, it is necessary to constantly improve preventive measures for labour protection aimed at reducing occupational risks.
介绍。飞机生产量的增加和扩大对参与生产过程的雇员的健康造成了额外的负担,因此,发生职业病和与生产有关的疾病的风险增加。 摘要本研究的目的是评估某飞机制造企业主要职业员工的职业健康风险。& # x0D;材料和方法。采用描述性统计方法对2017-2021年飞机制造企业(ABE)主要职业职工暂时性残疾(ITD)发生率进行研究。p <确定显著性水平;0.05 # x0D公司;结果。在分析期间,所有研究组中工作ABE的过渡段都有所增加。在ABE工作中,主要组的病例数和残疾天数的平均指标高于对照组的类似指标。在过渡时期的定性评估中,发现噪音和振动危险职业的雇员在致残病例数和致残天数方面的平均指标非常高,而接触化学品的工作人员的平均指标很高。的局限性。本研究的结果是由于一般发病率,不包括职业性,这需要进一步研究。 结论。在AВE工业发展的当前条件下,有必要不断完善旨在降低职业风险的劳动保护预防措施。
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引用次数: 0
Hygienic problems of the use of Vended Water (literature review) 使用自动售货水的卫生问题(文献综述)
Q4 Medicine Pub Date : 2023-10-09 DOI: 10.47470/0016-9900-2023-102-8-842-847
Gennady B. Yeremin, Natalya A. Mozzhukhina, Darya S. Borisova
A significant gain in the volume of sales of vended water, both throughout the world and in our country, makes it relevant to analyze the problems of ensuring the quality and safety of vended water. The original articles on the problems of using vended water, presented in the bibliographic and abstract databases and information systems PubMed, Scopus, Web of Science, eLIBRARY.RU, CyberLeninka, The Cochrane Library, met the criteria for compliance with the stated purpose and quality of research results, are analyzed. A total of ninty three full-text reports were identified by targeted search, of which 54 fully met these inclusion criteria. Vended water is one of the economically attractive ways to provide affordable drinking water with high organoleptic properties. National laws regulate the quality and safety of vended water differently: in some countries (Malaysia) vended water is regulated in one legal act together with packaged water and is considered as a food product, in others (USA) it is considered as non-communal public water supply, to which US Environmental Protection Agency (US EPA) requirements are applied. The Russian regulatory and legal framework in relation to vended water is in the process of formation, so far it has a recommendation character. The problem of microbiological safety of vended water is global. In the studies conducted, the safety of vended water was associated not only with the quality of water from the source of water supply and the method (or lack) of water treatment, but also with the location and design of water dispensers, the health status and hygiene skills of sellers/manufectures, and the hygiene skills of consumers, including cleanliness of hands and condition of containers (often reusable). The studies noted the importance of the quality of maintenance, disinfection of aquamats and quality control of vending water to ensure water quality and safety. When using reverse osmosis technologies in aquamats, the problem of reducing the mineralization of vended water also requires control of the total mineralization, calcium, and magnesium cations.
随着我国和世界各地自来水销售量的显著增长,分析自来水的质量和安全问题具有重要意义。在书目和摘要数据库和信息系统PubMed, Scopus, Web of Science, eLIBRARY中提供的关于使用自动供水问题的原始文章。RU、CyberLeninka、Cochrane Library符合研究目的和研究结果质量的标准,对其进行分析。通过目标检索共识别出93篇全文报告,其中54篇完全符合这些纳入标准。自动售货水是一种经济上有吸引力的方式,提供负担得起的高感官性能的饮用水。国家法律对瓶装水的质量和安全有不同的规定:在一些国家(马来西亚),瓶装水与包装水一起被视为食品,在另一些国家(美国),瓶装水被视为非公共供水,适用于美国环境保护署(US EPA)的要求。俄罗斯关于出售水的监管和法律框架正在形成过程中,到目前为止它具有推荐性。供水的微生物安全问题是一个全球性的问题。在进行的研究中,售水的安全性不仅与供水水源的水质和水处理方法(或缺乏)有关,还与饮水机的位置和设计、销售商/制造商的健康状况和卫生技能以及消费者的卫生技能有关,包括手的清洁度和容器(通常可重复使用)的状况。这些研究指出,维修质量、水塘消毒和自动售水质量控制对确保水质和安全至关重要。当在水层中使用反渗透技术时,降低流出水矿化的问题还需要控制总矿化、钙和镁阳离子。
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引用次数: 0
Comparative assessment of the carcinogenic risk arising from the release of products of high-temperature and low-temperature neutralization of medical waste into the air 高温和低温医疗废物中和产物释放到空气中致癌风险的比较评估
Q4 Medicine Pub Date : 2023-10-09 DOI: 10.47470/0016-9900-2023-102-8-750-756
Otari G. Khurtsilava, Olga V. Mironenko, Sergey N. Noskov, Khamzat K. Magomedov, Andrey V. Pankin, Ekaterina A. Fedorova, Denis A. Obukhov, Olga K. Suvorova
Introduction. The problem of neutralization/decontamination of medical waste generated in medical institutions occupies a significant place among the existing epidemiological and environmental problems. Domestic and foreign colleagues consider the use of thermal methods for the disposal of medical waste to be a priority. Despite technological advances in the system of purification of «exhaust» gases, the work of enterprises for the disposal of medical waste is still of concern to the population of the territories in which they operate. The objective of the study. The assessment of the impact of low-temperature and high-temperature thermal treatment of medical waste on the atmospheric air and public health in the zone of their influence to substantiate the laboratory control program using these technologies. Materials and methods. The work used sanitary-chemical methods for studying emissions from installations for the thermal treatment of medical waste, modelling the dispersion of emissions with the calculation of ground-level concentrations, and the methodology for assessing the risk to public health based on «Guidelines for assessing the risk to public health from exposure to chemicals polluting the environment». Results. The results of the calculation of the carcinogenic risk to public health from high-temperature neutralization technologies are assessed as the maximum allowable and acceptable, from the low-temperature method as acceptable. Limitations. Emissions from the main technologies for the disposal of medical waste included substances with a carcinogenic effect, but the carcinogenic risk was calculated only for those substances that had a carcinogenic potential factor. Conclusion. Based on the results of the study, when managing production laboratory control programs and monitoring atmospheric air in the impact zone of medical waste incineration enterprises, it is necessary to include the such components in the mandatory list of monitored indicators as sulfur dioxide, nitrogen dioxide, suspended solids, cadmium oxide, nitrogen oxide, dioxins, and benz/a/pyrene; in the operating area of installations for low-temperature thermal treatment of medical waste (autoclaving), it is necessary to control chemical components as follows: benzene, dimethylbenzene, methylbenzene, ethylbenzene, 2-butoxyethanol, butan-1-ol, propan-1-ol.
介绍。在现有的流行病学和环境问题中,医疗机构产生的医疗废物的中和/净化问题占有重要地位。国内外同行认为,利用热法处置医疗废物是一个优先事项。尽管在"废气"净化系统方面取得了技术进步,但企业处理医疗废物的工作仍然是其经营所在领土上的居民关注的问题。研究的目的。评估医疗废物低温和高温热处理对影响区内大气和公众健康的影响,以证实使用这些技术的实验室控制方案。 材料和方法。这项工作使用卫生化学方法来研究医疗废物热处理设施的排放,通过计算地面浓度来模拟排放的扩散,并根据《接触污染环境的化学品对公众健康的风险评估准则》评估对公众健康的风险的方法。结果。高温中和技术对公共健康的致癌风险计算结果被评估为最大允许和可接受,低温中和技术的致癌风险被评估为可接受。 的局限性。处置医疗废物的主要技术所产生的排放物包括具有致癌作用的物质,但致癌风险仅针对具有致癌潜在因素的物质进行了计算。结论。根据研究结果,在管理生产实验室控制方案和对医疗垃圾焚烧企业影响区大气空气进行监测时,有必要将二氧化硫、二氧化氮、悬浮物、氧化镉、氧化氮、二恶英、苯/a/芘等成分纳入监测指标强制清单;在医疗废物低温热处理(高压灭菌)装置的操作区内,需要对以下化学成分进行控制:苯、二甲苯、甲苯、乙苯、2-丁氧基乙醇、丁烷-1醇、丙烷-1醇。
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引用次数: 0
Determination of the microbial risk degree to health of the population provided with centralized water supply 集中供水人群微生物健康风险程度的测定
Q4 Medicine Pub Date : 2023-10-09 DOI: 10.47470/0016-9900-2023-102-8-768-774
Aleksandr A. Kovshov, Yuliya A. Novikova, Vladimir N. Fedorov, Nadezhda A. Tikhonova, Igor O. Myasnikov, Roman V. Buzinov
Introduction. Modern methodological approaches make it possible to assess the risk of waterborne bacterial intestinal infections, taking into account both the sanitary and hygienic conditions of water used by the population and the level of communal improvement of the territory. The purpose of the study was to assess the degree of epidemic danger of bacterial intestinal infections associated with the conditions of centralized drinking and household water supply, using the example of the subjects of the Northwestern Federal District. Materials and methods. The study tested the data of the federal statistical observation form No. 18 “Information on the sanitary condition of the subject”, the federal information fund of social and hygienic monitoring, and the Unified Interdepartmental Information and Statistical System. We analyzed the materials for 2022 in eleven subjects of the Northwestern Federal District. Method MR 2.1.10.0031-11 was taken as the basis for microbial risk assessment. Results. The Republic of Karelia, Vologda, Arkhangelsk, and Novgorod regions are characterized by an average degree of microbial risk in terms of the proportion of drinking water samples in the distribution network, in which generalized coliform bacteria were found; Novgorod region and the Republic of Karelia have a high degree of risk for E. coli. The lowest number of population provided with centralized water supply, corresponding to a high degree of microbial risk, was found in the Nenets Autonomous Okrug. This region is also characterized by the lowest average daily water consumption per capita. Limitations. The study tested the data on the subjects of the North-Western Federal District in 2022, the quality of drinking water was assessed only according to the results of laboratory studies conducted by the Federal Service for Supervision in Protection of the Rights of Consumer and Man Wellbeing. Conclusion. Most regions of the Russian North-West are characterized by an average degree of microbial risk, except for St. Petersburg, where a low degree of risk is established. The use of an alternative variant of risk ranking by 5 degrees (low, slightly increased, increased, significantly increased, high) showed that in the Republic of Karelia, Arkhangelsk and Vologda regions, and Nenets Autonomous Okrug, there is a significantly elevated degree of microbial risk.
介绍。考虑到居民用水的卫生和卫生条件以及该领土的公共改善程度,采用现代方法可以评估水源性肠道细菌感染的风险。本研究以西北联邦区为例,旨在评估肠道细菌感染的流行危险程度与集中饮用水和家庭供水条件的关系。材料和方法。这项研究检验了联邦统计观察表第18号“关于受试者卫生状况的信息”、联邦社会和卫生监测信息基金以及统一部门间信息和统计系统的数据。我们分析了西北联邦区11个科目的2022年教材。方法以mr2.1.10.0031 -11为微生物风险评价依据。 结果。卡累利阿共和国、沃洛格达、阿尔汉格尔斯克和诺夫哥罗德地区的特点是,就分配网络中饮用水样本的比例而言,存在平均程度的微生物风险,其中发现了广义大肠菌群;诺夫哥罗德地区和卡累利阿共和国感染大肠杆菌的风险很高。在涅涅茨自治区,获得集中供水的人口数量最少,对应于高度的微生物风险。该地区的人均日平均用水量也是最低的。 的局限性。该研究测试了2022年西北联邦区受试者的数据,饮用水质量仅根据联邦保护消费者权利和人类福祉监督局进行的实验室研究结果进行评估。结论。俄罗斯西北部的大多数地区的特点是微生物风险程度平均,但圣彼得堡的风险程度较低。使用风险等级按5度(低、略增加、增加、显著增加、高)排序的替代变量表明,在卡累利阿共和国、阿尔汉格尔斯克和沃洛格达地区以及涅涅茨自治区,微生物风险程度显著升高。
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引用次数: 0
Psychoemotional state during the formation of emotional burnout syndrome in middle-grade medical staff 中级医务人员情绪倦怠综合征形成过程中的心理情绪状态
Q4 Medicine Pub Date : 2023-10-09 DOI: 10.47470/0016-9900-2023-102-8-830-835
Marina V. Kuleshova, Vladimir A. Pankov
Introduction. The study of the specifics of the emotional burnout (EB) manifestation, the factors contributing to its occurrence in people of different occupations, is very relevant. However, the influence of personality factors on EB remains insufficiently resolved. The purpose of the study is to identify the relationship between anxiety, depression levels, and EB in health care workers. Materials and methods. An online study of the EB components, anxiety, and depression in health care occupations was carried out using V.V. Boyko’s questionnaire, Spielberger-Khanin and Zung scales. The research results are displayed as median, upper and lower quartiles, intensive and extensive indicators. The assessment of the relationship between variables was performed with the calculation of the Spearman correlation coefficient. Results. The formation of EB phases is characterized for the examined group: “Tension” – in 35.7 per 100 examined, “Resistance” – in 53.6 per 100 examined, “Exhaustion” – in 14.3 per 100 examined. The dominant symptoms are experience of traumatic circumstances (50.0%), reduction of occupational responsibilities (60.7%), emotional and moral disorientation (46.4%), expansion of the sphere of saving emotions (42.9%), and depersonalization (46.4%). Persons in whom any formed EB phase have a high level of trait and state anxiety, and depression. Among those surveyed with an unformed EB phase, the proportion of highly anxious individuals is significantly lower, and there are no signs of depression. Correlation analysis of the relationship revealed statistically significant relationships between the symptoms caused the formation of a particular EB phase and depression, anxiety. Limitations. The study is one-stage, performed with the participation of one professional group. Conclusion. A significant share of the health care occupations experience EB symptoms, and there is a reciprocal relationship between the EB severity and anxiety, and depression. In the majority of examined respondents, EB syndrome is in a dynamic development state. Prospective longitudinal studies are needed, in which a special place should be given to systematic clinical observation.
介绍。研究情绪倦怠的具体表现及其在不同职业人群中的发生因素具有重要意义。然而,人格因素对EB的影响尚未得到充分解决。& # x0D;本研究的目的是确定卫生保健工作者焦虑、抑郁水平与EB之间的关系。 材料和方法。采用V.V. Boyko量表、Spielberger-Khanin量表和Zung量表对医疗保健职业的EB成分、焦虑和抑郁进行了在线研究。研究结果以中位数、上四分位数和下四分位数、集约化和粗放化指标显示。通过计算Spearman相关系数来评估变量之间的关系。 结果。被检查组的EB相形成的特征是:“张力”-每100个被检查35.7个,“阻力”-每100个被检查53.6个,“衰竭”-每100个被检查14.3个。主要症状为创伤环境经验(50.0%)、职业责任减少(60.7%)、情绪和道德迷失(46.4%)、拯救情绪范围扩大(42.9%)和人格解体(46.4%)。任何形成EB期的人都有高水平的特质和状态焦虑和抑郁。在未形成EB期的被调查者中,高度焦虑个体的比例明显较低,且无抑郁迹象。相关性分析显示,导致某一特定EB期形成的症状与抑郁、焦虑有统计学意义。 的局限性。该研究是一个阶段,由一个专业小组参与。 结论。有相当一部分的医疗保健职业经历EB症状,并且EB严重程度与焦虑和抑郁之间存在相互关系。在大多数调查对象中,EB综合征处于动态发展状态。需要前瞻性的纵向研究,其中应特别重视系统的临床观察。
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