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Evaluation of Quality of Life in Infertile Couples 不孕夫妇生活质量评价
Pub Date : 2018-12-31 DOI: 10.33425/2639-9342.1069
B. Kaberi, S. Bhavana, Gautam Sonum
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引用次数: 0
The "Reproductive Transition": A Community-based Reproductive Health Surveillance Paradigm in Developing Countries "生殖过渡":发展中国家以社区为基础的生殖健康监测模式
Pub Date : 2018-10-30 DOI: 10.33425/2639-9342.1060
Abe N'Doumy Noël
The major question at the center of this study is the model for reading maternal and neonatal health problems in developing countries. On the subject, the demographic, epidemiological and statistical literature has accustomed us to a reading model based on observation and analysis at the micro-individual scale. The unit of analysis is the individual. This classic model of analysis, based on sociodemographic variables, has some effectiveness / relevance, but is still limited. It appears partial and static. In contrast to this individualistic and fixed approach, we propose a dynamic and community-based observation scale that induces the concept of "reproductive transition". The reproductive transition is defined as the transition from a high-risk situation in a community to a lower-risk situation over a sustainable period in reproductive health. Indeed, the operational approach leads us to four types of expected results that are four possible trends of sociological evolution of this reproductive health. These expected results are: The transition started; the problems are decreasing. The stationary situation; there is neither growth nor decay. The transition is mixed; some problems are growing, others are decreasing. The alarming situation; all problems have an ascending pace. "Reproductive transition" thus appears as an innovative model for reading reproductive health problems. Its scale of observation is the community and not the individual. It thus constitutes a relevant health surveillance support for communities where maternal, neonatal and infant morbidity and mortality appear to be endemic.
本研究中心的主要问题是发展中国家产妇和新生儿健康问题的阅读模型。在这个问题上,人口、流行病学和统计文献使我们习惯于一种基于微观个体尺度上的观察和分析的阅读模式。分析的单位是个体。这种基于社会人口变量的经典分析模型具有一定的有效性/相关性,但仍然有限。它看起来是局部的和静态的。与这种个人主义和固定的方法相反,我们提出了一个动态的、以社区为基础的观察尺度,引入了“生殖过渡”的概念。生殖过渡的定义是在一个可持续的生殖健康时期内,从一个社区的高风险状况过渡到低风险状况。实际上,业务方法使我们得到四种类型的预期结果,即生殖健康的社会演变的四种可能趋势。这些预期结果是:过渡开始;这些问题正在减少。静止状态;既没有增长也没有衰退。这种转变是复杂的;有些问题在增加,有些问题在减少。令人担忧的形势;所有的问题都有上升的速度。因此,“生殖过渡”似乎是解读生殖健康问题的一种创新模式。它的观察范围是社区而不是个人。因此,它对产妇、新生儿和婴儿发病率和死亡率似乎普遍存在的社区构成了相关的健康监测支助。
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引用次数: 0
Indications and Outcomes of Emergency Caesarean Section at St Paul's Hospital Medical College, Addis Ababa, Ethiopia 2017: (Afoul Month Retrospective Cohort Study) 2017年埃塞俄比亚亚的斯亚贝巴圣保罗医院医学院急诊剖宫产的适应证和结果:(4个月回顾性队列研究)
Pub Date : 2018-10-30 DOI: 10.33425/2639-9342.1053
Bizuneh Ayano, Ayana Guto
Background: Cesarean section (CS) rates and their indications vary all over the World. Audit of indications and factors affecting infant and maternal outcome remain an important activity in rationalizing the use of this major procedure in obstetrics practice. Cesarean section (CS) carries a higher maternal morbidity and mortality compared to vaginal delivery. No researches have been done on this area. Objective: To determine the leading indications for ECS and their associated maternal and neonatal outcomes in St. Paul’s Hospital Millennium Medical College (SPHMMC). Methodology: Retrospective facility-based study was used and data was collected by reviewing the log book of patients who underwent CS operations at St. Paul’s Hospital Millennium Medical College (SPHMMC) gynecology obstetric department from 1st February to 30th May 2017. The leading indications for Emergency Cesarean Section (ECS) were determined in terms of frequency and percentage. Clinical outcomes of the mothers and the delivered newborns were gauged by morbidity, mortality and survival rates (i.e. within the hospital confinement). Results: A total of 2345, deliveries were conducted, of which 582 deliveries were by cesarean section procedures making the institutional cesarean section rate of 24.8%. Records of patients who underwent Emergency Cesarean section (ECS) were retrieved and comprised the study population (N=522). Perinatal Asphyxia (PNA) was the most common cause of the neonatal death 6 (42.9%). Dystocia (26.4%) emerged as the leading indication for ECS followed by Non reassurance fetal heart rate pattern (NRFHRP) (18.8%). an association between indications of EC/S, Appearance, Pulse, Grimace, Activity, Respiration (APGAR) scores at 5th minute and fetal outcome with p value of <0.05 was observed. Conclusions: The institutional cesarean section rate is 25%, Maternal outcome was favorable with 94.8% of smooth post operation course and Surgical site wound infection was 63.0% among post operation complications that mothers developed. Dystocia (26.4%) emerged for ECS followed by Non reassurance fetal heart rate pattern (NRFHRP) (18.8%), Meconium stained Amniotic fluid (10.7%) and failed induction (5.4%). Neonatal outcome with survival rate of 94.1%. There was an association between indications of Emergency Cesarean Section (ECS), Appearance, Pulse, Grimace, Activity, Respiration (APGAR) scores at 5th minute and fetal outcome with p value of <0.05. [Ayano B, Guto A. Assessment of indications for emergency cesarean section and its outcomes at St. Paul’s Hospital Medical College, Addis Ababa, Ethiopia 2017: (afour month retrospective cohort study)].
背景:世界各地剖宫产率及其适应症各不相同。对影响母婴结局的指征和因素的审计仍然是在产科实践中合理化使用这一主要程序的重要活动。与阴道分娩相比,剖宫产的产妇发病率和死亡率更高。这方面还没有研究。目的:确定圣保罗医院千禧医学院(SPHMMC) ECS的主要适应症及其相关的孕产妇和新生儿结局。方法:采用基于医院的回顾性研究,并通过回顾2017年2月1日至5月30日在圣保罗医院千禧医学院(SPHMMC)妇科产科接受CS手术的患者日志收集数据。急诊剖宫产(ECS)的主要指征是根据频率和百分比确定的。通过发病率、死亡率和生存率(即住院期间)衡量母亲和分娩新生儿的临床结果。结果:共分娩2345例,其中剖宫产582例,机构剖宫产率为24.8%。检索急诊剖宫产(ECS)患者的记录,纳入研究人群(N=522)。围产期窒息(PNA)是新生儿死亡的最常见原因6(42.9%)。难产(26.4%)是ECS的主要指征,其次是非安心胎心率模式(NRFHRP)(18.8%)。5分钟时EC/S、外貌、脉搏、鬼脸、活动、呼吸(APGAR)评分与胎儿结局存在相关性,p值<0.05。结论:医院剖宫产率为25%,产妇结局良好,术后病程顺利率为94.8%,产妇术后并发症手术部位伤口感染率为63.0%。ECS出现难产(26.4%),其次是无保证胎心率(NRFHRP)(18.8%)、胎粪染色羊水(10.7%)和诱导失败(5.4%)。新生儿结局生存率94.1%。急诊剖宫产(ECS)指征、第5分钟外貌、脉搏、鬼脸、活动、呼吸(APGAR)评分与胎儿结局有相关性,p值<0.05。[Ayano B, Guto A.急诊剖宫产指征评估及其预后[j].埃塞俄比亚,亚的斯亚贝巴,2017(4个月回顾性队列研究)。
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引用次数: 7
Obstetric Culture in the Development of Reproductive Health 生殖健康发展中的产科文化
Pub Date : 2018-10-30 DOI: 10.33425/2639-9342.1059
Anoua Adou Serge Judicaël
Maternal and youngster wellbeing stays a current test in Côte d'Ivoire as a result of high maternal and kid death rates in that nation. This disappointment raises the restrictions of the biomedical sciences in conceptive wellbeing. In this field of wellbeing, thereis certainly a real existence quality issue. This worry is shared by socio-humanities. Actually, how might we clarify and comprehend the advancement of conceptive medical issues in moms and youngsters? All the work did rotates around the issue of "obstetric culture and conceptive wellbeing". As it were, how might we clarify and comprehend obstetric culture as a significant determinant in the improvement of regenerative wellbeing in Côte d'Ivoire? In this unique situation, reflections arranged through socio- anthropological exploration are continually upheld by the equivalent exact postulation: "Considering socio- social determinants explicit to the networks being referred to, blocking the strength of the mother-youngster couple, could add to opening the networks concentrated to a more secure parenthood." Starting from this basic point, systems for lessening dramatizations by considering the social markers of networks can be recognized just as activities for conduct change can be arranged. This direction appears to us a theory of conceivable answer for dodge the epidemiological imposing business model fundamental the methodology in general wellbeing. results and patients' pride during the birthing procedure. Care pilots are explicitly picked and prepared to pick up the trust and regard of patients, conventional maternity specialists, and biomedical suppliers. We depict a progressing obstetric consideration guide test case program utilizing fast cycle quality improvement techniques to rapidly distinguish usage triumphs and disappointments. This methodology enables cutting edge wellbeing laborers to issue tackle continuously and guarantees the program is exceptionally versatile to nearbyneeds. Conclusion : Care is a promising technique to defeat the "humanistic boundary" to emergency clinic conveyance by alleviating ill bred and harsh consideration. It offers an interest side way to deal with undignified obstetric consideration that enables the networks generally affected by the issue to lead the reaction. Results from a continuous experimental run program of obstetric consideration route will give important criticism from patients on the effect of this methodology and usage exercises to encourage replication in different settings.
由于科特迪瓦孕产妇和儿童死亡率高,孕产妇和儿童的健康状况目前仍是该国面临的一项考验。这种失望增加了生物医学科学在概念健康方面的限制。在这个幸福的领域里,存在着一个真实的生存质量问题。社会人文学科也有这种担忧。实际上,我们如何才能澄清和理解母亲和青少年怀孕医学问题的进展?所做的所有工作都围绕着“产科文化和孕妇健康”这一问题展开。可以说,我们如何澄清和理解产科文化是Côte科特迪瓦改善再生健康的重要决定因素?在这种独特的情况下,通过社会人类学探索安排的反思不断得到等价的精确假设的支持:“考虑到所提到的网络中明确的社会决定因素,阻止母亲-年轻人夫妇的力量,可能会增加开放网络,集中在更安全的父母关系上。”从这个基本点出发,就像可以安排行为改变的活动一样,可以认识到通过考虑网络的社会标记来减少戏剧化的系统。在我们看来,这个方向似乎是躲避流行病学强加的商业模式的一个可想象的答案,它是一般福利方法论的基础。结果与分娩过程中患者的自豪感。护理试点被明确挑选出来,并准备好获得患者、传统产科专家和生物医学供应商的信任和尊重。我们描述了一个进步的产科考虑指南测试用例程序利用快速周期质量改进技术来快速区分使用的胜利和失望。这种方法使尖端的福利劳动者能够不断地发布解决方案,并保证该方案能够满足附近的需求。结论:护理是一种很有前途的技术,通过减轻不良和苛刻的考虑,打破急诊诊所运送的“人文边界”。它提供了一种利益方面的方式来处理不体面的产科考虑,使一般受该问题影响的网络能够领导反应。从产科考虑路线的连续实验运行程序的结果将给予重要的批评,从病人对这种方法的影响和使用练习,以鼓励在不同的设置复制。
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引用次数: 1
Perception and Practice of Exercise during Pregnancy by Antenatal Women in Southeastern Nigeria 尼日利亚东南部产前妇女对怀孕期间运动的认知和实践
Pub Date : 2018-10-30 DOI: 10.33425/2639-9342.1057
Adinma J.I.B, Adinma E.D, Umeononihu O.S, Oguaka, Oyedum S.O
Background: Exercise in pregnancy is known to be beneficial to both the mother and the fetus during the course of pregnancy, labour/delivery and in postpartum recovery. There are few instances when exercise is contraindicated but even in most cases, the benefits outweigh the risks. It is important to study the level of awareness, perception and the practice of exercise in pregnancy which will form the reference point for policy formulation to address the identifiable areas of need. Aims and Objectives: To determine the perception and practice of exercise in pregnancy by women during an antenatal care outreach programme in Anambra state south-east Nigeria. Methodology: A cross-sectional, questionnaire-based study of 115 pregnant women who attended antenatal care outreach programme in two locations in Anambra state, south-east Nigeria. The data obtained was analysed using SPSS version 20.0. Results: A little fewer than half of the respondents 52 (45.2%) were of age 26-30 years, while the predominant 79 (58.7%) gestational age group was ˂ 28 weeks and most parity79 (68.7%) was 1-4. Over half of the respondents 68 (59.1%) belonged to the social class 3 and nearly half of the respondents were traders 56 (48.7%). As high as 100 (87%) had heard about exercise in pregnancy while 80 (69.6%) had engaged in exercise while pregnant. Majority of the respondents 73 (63.5%) had engaged in walking as a form of exercise, while 21 (18.3%), 7 (6.1%), 4 (3.5%), 1 (0.9%), 1 (0.9%) had engaged in dancing, jogging, skipping, swimming and jumping respectively. Forty-two (36.5%) had engaged in exercise before 28 weeks of gestation while 18 (15.7%) and 2 (1.7%) did so at 28-36 weeks and 37-42 weeks respectively. The commonest exercise amongst the various social classes was walking, followed at a distance by dancing, jogging, skipping, jumping and swimming respectively. The most perceived benefits of exercise in pregnancy by the participants are as a necessity to life 105 (91.3%) and enhancement of labour/delivery 92 (80%) while 10 (8.7%) had the misconception that pregnant women should not engage in exercise. Conclusion: Although majority of the antenatal women in the population studied engage in exercise, this is oftentimes restricted to “walking”. In addition, a number of the respondents had negative perception as to the value of exercise in pregnancy. There is an urgent need to educate the women during the pre-conception and early pregnancy periods to initiate, sustain, modify and expand the range of exercises undertaken while pregnant. This will go a long way to avail the women and their unborn babies the potential benefits associated with attaining the recommended level of exercise in pregnancy.
背景:众所周知,孕期运动对母亲和胎儿在妊娠、分娩和产后恢复期间都是有益的。在少数情况下,运动是禁忌的,但即使在大多数情况下,好处大于风险。重要的是要研究怀孕期间运动的认识、感知和实践水平,这将成为制定政策的参考点,以解决可确定的需要领域。目的和目标:在尼日利亚东南部阿南布拉州的产前保健推广方案中,确定妇女对怀孕期间运动的认识和实践。方法:对尼日利亚东南部阿南布拉州两个地点参加产前保健外展方案的115名孕妇进行横断面问卷调查。所得数据采用SPSS 20.0版进行分析。结果:26 ~ 30岁占52例(45.2%),胎龄小于28周占58.7%,1 ~ 4周占68.7%。超过一半的受访者68人(59.1%)属于社会阶层3,近一半的受访者56人是交易员(48.7%)。高达100人(87%)曾听说孕期运动,80人(69.6%)曾在孕期运动。多数受访者中有73人(63.5%)曾以步行作为运动,其余分别有21人(18.3%)、7人(6.1%)、4人(3.5%)、1人(0.9%)、1人(0.9%)、1人(0.9%)曾以跳舞、慢跑、跳高、游泳及跳高。42人(36.5%)在妊娠28周之前有运动,18人(15.7%)和2人(1.7%)在妊娠28-36周和37-42周有运动。在不同的社会阶层中,最常见的运动是散步,其次是跳舞、慢跑、跳绳、跳绳和游泳。参与者认为怀孕期间运动的最大好处是作为生命的必需品105人(91.3%)和促进分娩/分娩92人(80%),而10人(8.7%)错误地认为孕妇不应该从事运动。结论:虽然研究人群中大多数产前妇女从事运动,但这通常仅限于“散步”。此外,一些受访者对怀孕期间锻炼的价值有负面看法。迫切需要教育妇女在孕前和怀孕早期开始、维持、修改和扩大怀孕期间进行的运动范围。这将大大有助于妇女和她们未出生的婴儿在怀孕期间达到建议的运动水平所带来的潜在好处。
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引用次数: 2
Genital Schistosomiasis as A Risk for Genital Cancer 生殖器血吸虫病是生殖器癌的风险之一
Pub Date : 2018-10-30 DOI: 10.33425/2639-9342.1058
Grácio Maria A
With the present editorial containing more recent information we wish to alert the reader to genital schistosomiasis as a potential risk for genital cancer. Since 1899 that the female genital schistosomiasis (FGS) has received the attention of the scientific community. Effectively, the oldest published FGS case was reported in the Lancet in 1899 [10]. More recently (during the past five years), the authors [11] have investigated "the impact of schistosomiasis by S. haematobium on the high-risk human papillomavirus (HPV) and development of atypical cells in a group of rural Zimbabwean women with confirmed high-risk HPV". Their results have showed that between thirty seven women re-examined, genital S. haematobium of a duration of a minimum of five years, was associated with development of high-grade squamous intraepithelial neoplasia, but not with persistent highrisk HPV.
目前的社论包含了更多的最新信息,我们希望提醒读者生殖器血吸虫病是生殖器癌的潜在风险。自1899年以来,女性生殖器血吸虫病(FGS)一直受到科学界的重视。实际上,最早发表的FGS病例于1899年在《柳叶刀》上报道[10]。最近(在过去的5年里),这组作者[11]研究了“S. haematobium血吸虫病对高风险人乳头瘤病毒(HPV)的影响以及在一组确诊高风险HPV的津巴布韦农村妇女中非典型细胞的发展”。他们的研究结果表明,在37名重新检查的女性中,持续时间至少5年的生殖器血红梭菌与高度鳞状上皮内瘤变的发展有关,但与持续的高风险HPV无关。
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引用次数: 0
Would Human Preimplantation Gene Therapy Based on CRISPR-Cas9 Genome Editing Increase Cancer Risk in the Offspring? 基于CRISPR-Cas9基因组编辑的人类胚胎植入前基因治疗会增加后代患癌症的风险吗?
Pub Date : 2018-10-30 DOI: 10.33425/2639-9342.1056
J. Tesarik, Raquel Mendoza‐Tesarik, C. Mendoza
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引用次数: 0
Management of Adnexal Masses During Pregnancy: A Literature Review 妊娠期间附件肿块的处理:文献综述
Pub Date : 2018-10-30 DOI: 10.33425/2639-9342.1055
Carbonaro A, Distefano R, S. M., G. F, C. L., Palumbo M
Although the exact incidence of adnexal masses in pregnancy is not clear, its occurrence is considered very common. The majority of them are functional cysts (follicular, corpus luteum and theca lutein cysts), dermoid cysts and cystadenomas, and they resolve spontaneously, but a considerable percentage can be malignant. The use of ultrasounds in conjunction with IOTA's guidelines is crucial in order to stratify the risk and help the physician to determine the management. The very recent ADNEX model, developed by IOTA's group, opens up some interesting possibilities in this scenario. Management can be conservative, surgical and chemotherapeutic depending on the size, malignancy risk and gestational age.
 In this study we reviewed the epidemiology of adnexal masses during pregnancy and their potential complications, the available diagnostic procedures and the possible management options.
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引用次数: 0
Onchocerciasis and its Impact on the Female Reproductive System: A Neglected Situation? 盘尾丝虫病及其对女性生殖系统的影响:一个被忽视的情况?
Pub Date : 2018-08-31 DOI: 10.33425/2639-9342.1048
A. GrácioMaria, Grácio António Js
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引用次数: 0
Autologous Adipose-Derived Stem Cell Treatment for Women with Genital Lichen Sclerosus 自体脂肪源性干细胞治疗女性生殖器硬化性地衣
Pub Date : 2018-08-31 DOI: 10.33425/2639-9342.1052
N. Newman, Nualla Rogowski R.N, Daniel Newman, Dodanim Talavera-Adame
Background: Lichen Sclerosus (LS) is a debilitating disease that causes chronic inflammation most commonly noted in the anogenital region. Many patients with genital Lichen Sclerosus report unsuccessful results with standard treatment options including steroids, calcineurin inhibitors, and/or hormone therapy. These patients presented to our clinic seeking autologous adipose-derived stem cell treatment (AASCT). Methods: Data was collected through questionnaires regarding disease symptoms on a daily basis and quality of life indicators. Questionnaires were completed by patients before and three months post AASCT. One hundred and eleven consecutive women who presented to our clinic from 2011 to 2015 with symptomatic, clinically apparent or biopsy proven genital Lichen Sclerosus were given the questionnaires and 100 of these patients completed both questionnaires. Results: The questionnaires were statistically analyzed to compare improvement in symptoms before and three months after AASCT. The improvement in every symptom was statistically significant (P<0.001). These symptoms included: itching, burning, pain, discomfort, blisters, ulcers, fusing, tearing, and fissures. Improvement in ability to carry out daily activities (such as voiding, bowel movements, exercising, intercourse, and wearing pants/ underwear) also showed substantial improvement that was statistically significant (P<0.001). Conclusion: Given the results, we can confidently say that AASCT is a promising new alternative treatment for patients suffering from Lichen Sclerosus. Additional AASCT may provide patients with further improvement in their symptoms. At present, long term follow-up is being conducted by our clinic to evaluate the course of the disease and the duration of improvements achieved from this treatment.
背景:硬化地衣(LS)是一种使人衰弱的疾病,引起慢性炎症,最常见于肛门生殖器区域。许多患有生殖器硬化地衣的患者报告使用类固醇、钙调磷酸酶抑制剂和/或激素治疗等标准治疗方案均不成功。这些患者来到我们诊所寻求自体脂肪源性干细胞治疗(AASCT)。方法:通过日常疾病症状和生活质量指标问卷收集资料。患者分别在AASCT术前和术后3个月完成问卷调查。2011年至2015年,连续111例出现症状性、临床表现明显或活检证实的生殖器硬化地衣的女性患者接受问卷调查,其中100例患者完成了两份问卷。结果:对问卷进行统计分析,比较AASCT前后三个月症状的改善情况。各症状改善均有统计学意义(P<0.001)。这些症状包括:瘙痒、灼烧、疼痛、不适、水泡、溃疡、融合、撕裂和裂缝。日常活动能力的改善(如排尿、排便、运动、性交和穿裤子/内衣)也显示出显著的改善,具有统计学意义(P<0.001)。结论:鉴于结果,我们可以自信地说,AASCT是一种有希望的新的替代治疗方法。额外的AASCT可能会进一步改善患者的症状。目前,我们的诊所正在进行长期随访,以评估疾病的病程和这种治疗所取得的改善持续时间。
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引用次数: 4
期刊
Gynecology & reproductive health
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