Summary Introduction: Murraya koenigii L. and Ficus carica L. have been traditionally used in folk medicine for treating several diseases. Objective: The present study was proposed to investigate the phytochemical constituents and antioxidant potential of hydro-alcoholic and aqueous extracts of leaves of M. koenigii and dried fruits of F. carica. Methods: Phytochemical screening was performed using different methods and antioxidant activity was evaluated by measuring total phenolic content, total antioxidant capacity (TAOC), hydrogen peroxide (H2O2) scavenging activity, DPPH radical-scavenging activity, reducing power assay, nitric oxide radical scavenging activity, and superoxide radical-scavenging activity. Results: The results showed that the hydro-alcoholic and aqueous extracts of leaves of M. koenigii and dried fruits of F. carica possess a significant quantity of flavonoids, saponins, terpenoids (9.0%, 0.9%, 0.6% and 7.3%, 8.7%, 0.44%, respectively) and also possess a significant antioxidant activity as evaluated by employing different antioxidant assays. Conclusion: It may be concluded that the hydro-alcoholic and aqueous extracts of leaves of M. koenigii and dried fruits of F. carica exhibit significant antioxidant activity.
{"title":"Evaluation of phytochemical constituents and antioxidant potential of hydro-alcoholic and aqueous extracts of Murraya koenigii L. and Ficus carica L.","authors":"S. Farooq, Randhir Singh, V. Saini","doi":"10.2478/hepo-2019-0021","DOIUrl":"https://doi.org/10.2478/hepo-2019-0021","url":null,"abstract":"Summary Introduction: Murraya koenigii L. and Ficus carica L. have been traditionally used in folk medicine for treating several diseases. Objective: The present study was proposed to investigate the phytochemical constituents and antioxidant potential of hydro-alcoholic and aqueous extracts of leaves of M. koenigii and dried fruits of F. carica. Methods: Phytochemical screening was performed using different methods and antioxidant activity was evaluated by measuring total phenolic content, total antioxidant capacity (TAOC), hydrogen peroxide (H2O2) scavenging activity, DPPH radical-scavenging activity, reducing power assay, nitric oxide radical scavenging activity, and superoxide radical-scavenging activity. Results: The results showed that the hydro-alcoholic and aqueous extracts of leaves of M. koenigii and dried fruits of F. carica possess a significant quantity of flavonoids, saponins, terpenoids (9.0%, 0.9%, 0.6% and 7.3%, 8.7%, 0.44%, respectively) and also possess a significant antioxidant activity as evaluated by employing different antioxidant assays. Conclusion: It may be concluded that the hydro-alcoholic and aqueous extracts of leaves of M. koenigii and dried fruits of F. carica exhibit significant antioxidant activity.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"65 1","pages":"17 - 7"},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43555146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Kowalska, K. Seidler-Łożykowska, M. Jakubowska, D. Drożdżyński
Summary Objective: Chamomile plants (Chamomilla recutita L. Rausch) are often attacked by pests, which usually cause the decrease of raw material yield and its quality. The objects of field trial were two chamomile cultivars: Złoty Łan (4n) and Promyk (2n) cultivated under organic regime. The aim of this study was to evaluate of impact of the spinosad treatment and its time of application on two chamomile cultivars: cv. Promyk – 2n and cv. Złoty Łan – 4n exposed to insect pests. Methods: The first treatment with spinosad as a preventative control (P) was performed in the early phase of plant development (seven leaves). Intervention (I) treatment was made in green bud phase. In both terms of observation insect pests were observed and collected. In each spraying application of 0.06 g of spinosad per 1 liter of water was used. Results: Spinosad was able to limit the number of pest population and finally increased yielding of the treated cultivars as compared to the untreated plants. Time of spinosad application for cv. Złoty Łan plants was not statistically siginificant, although was more effective for the preventative treatment of cv. Promyk in the increasing of the plant biomass (283.8 g · m−2) and seed (32 g · m−2) yields than intervention. Conclusion: Protection treatment with spinosad might be recommended in chamomile cultivation and it is more effective than intervention in diploid cultivar which begin blooming earlier than tetraploid. Essential oil content was not related with protection treatment for diploid cultivar, although intervention in tetraploid cultivar caused higher content of oil.
{"title":"Does time of protective procedure and genotype of chamomile affect yield?","authors":"J. Kowalska, K. Seidler-Łożykowska, M. Jakubowska, D. Drożdżyński","doi":"10.2478/hepo-2019-0020","DOIUrl":"https://doi.org/10.2478/hepo-2019-0020","url":null,"abstract":"Summary Objective: Chamomile plants (Chamomilla recutita L. Rausch) are often attacked by pests, which usually cause the decrease of raw material yield and its quality. The objects of field trial were two chamomile cultivars: Złoty Łan (4n) and Promyk (2n) cultivated under organic regime. The aim of this study was to evaluate of impact of the spinosad treatment and its time of application on two chamomile cultivars: cv. Promyk – 2n and cv. Złoty Łan – 4n exposed to insect pests. Methods: The first treatment with spinosad as a preventative control (P) was performed in the early phase of plant development (seven leaves). Intervention (I) treatment was made in green bud phase. In both terms of observation insect pests were observed and collected. In each spraying application of 0.06 g of spinosad per 1 liter of water was used. Results: Spinosad was able to limit the number of pest population and finally increased yielding of the treated cultivars as compared to the untreated plants. Time of spinosad application for cv. Złoty Łan plants was not statistically siginificant, although was more effective for the preventative treatment of cv. Promyk in the increasing of the plant biomass (283.8 g · m−2) and seed (32 g · m−2) yields than intervention. Conclusion: Protection treatment with spinosad might be recommended in chamomile cultivation and it is more effective than intervention in diploid cultivar which begin blooming earlier than tetraploid. Essential oil content was not related with protection treatment for diploid cultivar, although intervention in tetraploid cultivar caused higher content of oil.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"65 1","pages":"1 - 6"},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42453954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Bogacz, Marlena Wolek, A. Górska, E. Leporowska, D. Procyk, Piotr Kolenda, M. Litwiniuk, I. Uzar, A. Gryszczyńska, Z. Łowicki, B. Czerny
Summary Introduction: Plants are a rich source of healing substances. Cancer is a leading cause of death worldwide while breast cancer is the most common cancer among women. Circulating tumour cells (CTCs) are potential founder cells for metastasis. Therefore, their assessment may be used for monitoring of treatment as well as detecting cancer metastatis. Hence, it is suggested that the number of CTCs may be a valuable tumour biomarker during therapy. Objective: The purpose of this study was to detect CTCs in breast cancer and to validate the method of assessment of CTC count using CytoTrack CT11 technology. Methods: MCF-7 cells were sorted by a FACSARIA flow cytometer from blood samples derived from patients who have not been diagnosed with cancer. Identification and quantitative assessment of MCF-7 cells in blood samples were determined by flow sorting. Then, blood samples containing MCF-7 cells or without MCF-7 were scanned with the use of an automated fluorescence scanning microscope. Results: In in vitro model analysing the glass CytoDisc™ with stained MCF-7 cells, we noted the correlation between the amount of observed tumour cells and expected number of tumour cells. Moreover, coefficient of variation in case of the recovery rate of the assumed number of MCF-7 cells was 30%, 17%, 18% and 15%, respectively. Conclusion: Our study suggest that CTCs could be predictive factor in patients with metastatic cancer especially in breast cancer.
{"title":"Detection of circulating tumour cells in the breast cancer using CytoTrack system","authors":"A. Bogacz, Marlena Wolek, A. Górska, E. Leporowska, D. Procyk, Piotr Kolenda, M. Litwiniuk, I. Uzar, A. Gryszczyńska, Z. Łowicki, B. Czerny","doi":"10.2478/hepo-2019-0023","DOIUrl":"https://doi.org/10.2478/hepo-2019-0023","url":null,"abstract":"Summary Introduction: Plants are a rich source of healing substances. Cancer is a leading cause of death worldwide while breast cancer is the most common cancer among women. Circulating tumour cells (CTCs) are potential founder cells for metastasis. Therefore, their assessment may be used for monitoring of treatment as well as detecting cancer metastatis. Hence, it is suggested that the number of CTCs may be a valuable tumour biomarker during therapy. Objective: The purpose of this study was to detect CTCs in breast cancer and to validate the method of assessment of CTC count using CytoTrack CT11 technology. Methods: MCF-7 cells were sorted by a FACSARIA flow cytometer from blood samples derived from patients who have not been diagnosed with cancer. Identification and quantitative assessment of MCF-7 cells in blood samples were determined by flow sorting. Then, blood samples containing MCF-7 cells or without MCF-7 were scanned with the use of an automated fluorescence scanning microscope. Results: In in vitro model analysing the glass CytoDisc™ with stained MCF-7 cells, we noted the correlation between the amount of observed tumour cells and expected number of tumour cells. Moreover, coefficient of variation in case of the recovery rate of the assumed number of MCF-7 cells was 30%, 17%, 18% and 15%, respectively. Conclusion: Our study suggest that CTCs could be predictive factor in patients with metastatic cancer especially in breast cancer.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"65 1","pages":"31 - 36"},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43123633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Schmidt-Przewozna, A. Villavicencio, A. Kicińska-Jakubowska, Karolina Zajączek, A. Brandys
Summary Introduction: Coreopsis tinctoria Nutt. is an annual plant with small flowers in yellow and claret. In dyeing process, a whole range of colours can be obtained using various methods. Objective: The aim of the study was to present a wide range of colors of the little-known plant C. tinctoria. and its health promoting properties. Methods: In our research, we selected 3 types of wool: Polish Merino, Żelaźnieńska, and Polish Lowland Sheep and compared the colours obtained on these wools using 6 dyeing methods. Results: The results indicate that the basic colour of wool influences the intensity of colour after dyeing as well as the type of the used mordant, which determines the obtained colour. A whole range of very intense colours was obtained from very small flowers of C. tinctoria. Conclusions: Flowers are a very good and efficient raw material that gives intense colors on wool. An additional advantage is the plant's health-promoting properties. The plant is still little explored in this respect.
{"title":"Coreopsis tinctoria Nutt. as a source of many colours","authors":"K. Schmidt-Przewozna, A. Villavicencio, A. Kicińska-Jakubowska, Karolina Zajączek, A. Brandys","doi":"10.2478/hepo-2019-0026","DOIUrl":"https://doi.org/10.2478/hepo-2019-0026","url":null,"abstract":"Summary Introduction: Coreopsis tinctoria Nutt. is an annual plant with small flowers in yellow and claret. In dyeing process, a whole range of colours can be obtained using various methods. Objective: The aim of the study was to present a wide range of colors of the little-known plant C. tinctoria. and its health promoting properties. Methods: In our research, we selected 3 types of wool: Polish Merino, Żelaźnieńska, and Polish Lowland Sheep and compared the colours obtained on these wools using 6 dyeing methods. Results: The results indicate that the basic colour of wool influences the intensity of colour after dyeing as well as the type of the used mordant, which determines the obtained colour. A whole range of very intense colours was obtained from very small flowers of C. tinctoria. Conclusions: Flowers are a very good and efficient raw material that gives intense colors on wool. An additional advantage is the plant's health-promoting properties. The plant is still little explored in this respect.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"65 1","pages":"56 - 61"},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43241419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Nowak, A. Klimowicz, Wiktoria Duchnik, Ł. Kucharski, Katarzyna Florkowska, Anna Muzykiewicz, D. Wira, Joanna Zielonkabrzezicka, Anita Siedłowska, Kinga Nadarzewska
Summary Introduction: Fireweed (Epilobium angustifolium (L.) Holub) is a common weed growing on meadows, roadside and agricultural wasteland, creating vast, rapidly spreading fields. Objective: The aim of the study was to evaluate the antioxidant activity of extracts from fresh fireweed, harvested at three ripening stages. Methods: Analysis of antioxidative activity was carried out by DPPH, ABTS and FRAP methods. Total polyphenol and total flavonoid content were also determined. Plant material was extracted using ultra-sound-assisted green extraction technique with methanol, ethanol and isopropanol at different concentrations and water. Results: The highest antioxidant activity evaluated by DPPH, ABTS and FRAP was found for the extracts prepared in 70% ethanol. The highest content of total polyphenols were observed in extracts in 70% ethanol, whereas the highest content of flavonoids extracts in undiluted methanol. Conclusion: Epilobium angustifolium harvested at fruit ripening stage seems to be a valuable source of antioxidants.
{"title":"Application of green-extraction technique to evaluate of antioxidative capacity of wild population of fireweed (Epilobium angustifolium)","authors":"A. Nowak, A. Klimowicz, Wiktoria Duchnik, Ł. Kucharski, Katarzyna Florkowska, Anna Muzykiewicz, D. Wira, Joanna Zielonkabrzezicka, Anita Siedłowska, Kinga Nadarzewska","doi":"10.2478/hepo-2019-0022","DOIUrl":"https://doi.org/10.2478/hepo-2019-0022","url":null,"abstract":"Summary Introduction: Fireweed (Epilobium angustifolium (L.) Holub) is a common weed growing on meadows, roadside and agricultural wasteland, creating vast, rapidly spreading fields. Objective: The aim of the study was to evaluate the antioxidant activity of extracts from fresh fireweed, harvested at three ripening stages. Methods: Analysis of antioxidative activity was carried out by DPPH, ABTS and FRAP methods. Total polyphenol and total flavonoid content were also determined. Plant material was extracted using ultra-sound-assisted green extraction technique with methanol, ethanol and isopropanol at different concentrations and water. Results: The highest antioxidant activity evaluated by DPPH, ABTS and FRAP was found for the extracts prepared in 70% ethanol. The highest content of total polyphenols were observed in extracts in 70% ethanol, whereas the highest content of flavonoids extracts in undiluted methanol. Conclusion: Epilobium angustifolium harvested at fruit ripening stage seems to be a valuable source of antioxidants.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"65 1","pages":"18 - 30"},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48931629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Ogbole, Toluwanimi E. Akinleye, Peter A Segun, P. Fasinu
Summary Introduction: Combretum species has been utilised for decades in African indigenous medical practices for the treatment of several parasitic infections. Objectives: This study aims at investigating the antileishmanial, antiplasmodial and antitrypanosomal properties of Combretum racemosum, Combretum platypterum and Combretum zenkeri. Methods: The leaf extracts of the plants were screened against two strains of Plasmodium falciparum using Plasmodium lactate dehydrogenase (pLDH) assay; promastigote and amastigote forms of Leishmania donovani; and Trypanosoma brucei brucei using Alamar Blue assay. Cytotoxicity screening were also carried out on African green monkey kidney cell line (Vero) and human monocytic leukemia (THP-1) cell lines. Results: C. racemosum was active against chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of P. falciparum (IC50 of 25.6 and 26.7 µg/ml, respectively) and exerted significant antiprotozoal activities against T. brucei brucei (IC50 = 18.44 µg/ml). The extract of C. platypterum displayed a slightly lower antiplasmodial activity when compared to C. racemosum, while C. zenkeri was inactive against the parasites. In addition, the extracts failed to display significant inhibitory activity on the proliferation of L. donovani. Conclusions: This study supports the ethnomedicinal use of C. racemosum. Further research needs to be carried out to identify the antiprotozoal compounds in C. racemosum, as this could be explored for possible antiprotozoal drug development.
{"title":"Antiprotozoal investigation of three Combretum species (Combretaceae) growing in Nigeria","authors":"O. Ogbole, Toluwanimi E. Akinleye, Peter A Segun, P. Fasinu","doi":"10.2478/hepo-2019-0024","DOIUrl":"https://doi.org/10.2478/hepo-2019-0024","url":null,"abstract":"Summary Introduction: Combretum species has been utilised for decades in African indigenous medical practices for the treatment of several parasitic infections. Objectives: This study aims at investigating the antileishmanial, antiplasmodial and antitrypanosomal properties of Combretum racemosum, Combretum platypterum and Combretum zenkeri. Methods: The leaf extracts of the plants were screened against two strains of Plasmodium falciparum using Plasmodium lactate dehydrogenase (pLDH) assay; promastigote and amastigote forms of Leishmania donovani; and Trypanosoma brucei brucei using Alamar Blue assay. Cytotoxicity screening were also carried out on African green monkey kidney cell line (Vero) and human monocytic leukemia (THP-1) cell lines. Results: C. racemosum was active against chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of P. falciparum (IC50 of 25.6 and 26.7 µg/ml, respectively) and exerted significant antiprotozoal activities against T. brucei brucei (IC50 = 18.44 µg/ml). The extract of C. platypterum displayed a slightly lower antiplasmodial activity when compared to C. racemosum, while C. zenkeri was inactive against the parasites. In addition, the extracts failed to display significant inhibitory activity on the proliferation of L. donovani. Conclusions: This study supports the ethnomedicinal use of C. racemosum. Further research needs to be carried out to identify the antiprotozoal compounds in C. racemosum, as this could be explored for possible antiprotozoal drug development.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"65 1","pages":"37 - 44"},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48074691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Igbe, O. Edosuyi, A. Okhuarobo, Adarki Pongri, N. Maduako, Isaac Ehimen
Summary Introduction: Potato (Solanum tuberosum L.) is an important vegetable crop in Syria. Potato tuber moth Cussonia barteri is a small tree that grows in the sub-Saharan part of Africa. Various parts of the plant are used for the treatment of a variety of ailments in ethno-medicine. Objective: To evaluate the anti-inflammatory and analgesic effect of the methanol leaf extract of Cussonia barteri. Material and methods: The leaves were air-dried, powdered and repeatedly extracted with methanol using a Soxhlet apparatus. The resulting methanol extract (100, 200 and 400 mg/kg) was evaluated for anti-inflammatory activity using carrageenan-induced paw oedema, xylene-induced ear oedema and formalin-induced arthritis tests. Analgesic effect was evaluated using acetic acid-induced mouse writhing, hot plate and tail flick tests. Results: All doses of the extract significantly (p<0.05) reduced carrageenan-induced paw oedema, however the 400 mg/kg dose gave a sustained effect. The extract significantly inhibited xylene induced ear oedema at all doses. There were no significant (p>0.05) reductions in paw swellings due to formalin. In the acetic acid induced writhing test, the extract significantly (p<0.05) decreased writhing at 400 mg/kg only. Reaction times were not significantly different from the control in the hot plate and tail flick tests. Conclusion: This study has shown that the methanol extract possesses acute anti-inflammatory and peripherally mediated analgesic effects.
{"title":"Preliminary assessment of the anti-inflammatory and analgesic effects of methanol leaf extract of Cussonia barteri (Araliaceae) in rodents","authors":"I. Igbe, O. Edosuyi, A. Okhuarobo, Adarki Pongri, N. Maduako, Isaac Ehimen","doi":"10.2478/hepo-2019-0015","DOIUrl":"https://doi.org/10.2478/hepo-2019-0015","url":null,"abstract":"Summary Introduction: Potato (Solanum tuberosum L.) is an important vegetable crop in Syria. Potato tuber moth Cussonia barteri is a small tree that grows in the sub-Saharan part of Africa. Various parts of the plant are used for the treatment of a variety of ailments in ethno-medicine. Objective: To evaluate the anti-inflammatory and analgesic effect of the methanol leaf extract of Cussonia barteri. Material and methods: The leaves were air-dried, powdered and repeatedly extracted with methanol using a Soxhlet apparatus. The resulting methanol extract (100, 200 and 400 mg/kg) was evaluated for anti-inflammatory activity using carrageenan-induced paw oedema, xylene-induced ear oedema and formalin-induced arthritis tests. Analgesic effect was evaluated using acetic acid-induced mouse writhing, hot plate and tail flick tests. Results: All doses of the extract significantly (p<0.05) reduced carrageenan-induced paw oedema, however the 400 mg/kg dose gave a sustained effect. The extract significantly inhibited xylene induced ear oedema at all doses. There were no significant (p>0.05) reductions in paw swellings due to formalin. In the acetic acid induced writhing test, the extract significantly (p<0.05) decreased writhing at 400 mg/kg only. Reaction times were not significantly different from the control in the hot plate and tail flick tests. Conclusion: This study has shown that the methanol extract possesses acute anti-inflammatory and peripherally mediated analgesic effects.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"65 1","pages":"22 - 31"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45482710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Summary A lot of products from food category specified in Regulation No. 609/2013 may contain herbal substances or their preparations. Definitions of food for infants and toddlers, food for special medical purposes, and total diet replacement for weight control are now clearly regulated by UE food legislation. The concept and definition of foodstuffs for particular nutritional published in Directive 2009/39/EC of the European Parliament and Council of 6 May 2009 do not apply. On 22 February 2019, Commission Delegated Regulation (EU) 2016/128 complementary to Regulation (EU) No. 609/2013, regarding specific compositional and information requirements for food of special medical purposes was applied. Novel foods and novel food ingredients are foods which have not been used for human consumption in UE to a significant degree before 15 May 1997.
{"title":"Fundamental regulations concerning novel food products and food for special medical purposes with plant ingredients","authors":"Justyna Baraniak, Małgorzata Kania-Dobrowolska","doi":"10.2478/hepo-2019-0019","DOIUrl":"https://doi.org/10.2478/hepo-2019-0019","url":null,"abstract":"Summary A lot of products from food category specified in Regulation No. 609/2013 may contain herbal substances or their preparations. Definitions of food for infants and toddlers, food for special medical purposes, and total diet replacement for weight control are now clearly regulated by UE food legislation. The concept and definition of foodstuffs for particular nutritional published in Directive 2009/39/EC of the European Parliament and Council of 6 May 2009 do not apply. On 22 February 2019, Commission Delegated Regulation (EU) 2016/128 complementary to Regulation (EU) No. 609/2013, regarding specific compositional and information requirements for food of special medical purposes was applied. Novel foods and novel food ingredients are foods which have not been used for human consumption in UE to a significant degree before 15 May 1997.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"65 1","pages":"64 - 68"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41617167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Muzykiewicz, A. Nowak, Joanna Zielonka-Brzezicka, Katarzyna Florkowska, Wiktoria Duchnik, A. Klimowicz
Summary Introduction: Hop (Humulus lupulus L.) is a common plant in Europe, with many beneficial health effects. In addition to the use in brewing, hops are a valuable source of active substances used in conventional and folk medicine, such as humulones and lupulones, as well as antioxidants, including phenolic compounds. Objective: The aim of the study was to evaluate and compare the antioxidant activity of alcoholic extracts of fresh hop leaves collected in 2017 and 2018. Material and methods: The raw material consisting of fresh hop leaves was extracted using ultrasound-assisted extraction. Methyl, ethyl and isopropyl alcohol at three concentrations were used as extractants. The antioxidant activity of extracts was determined using DPPH and FRAP methods. Total phenolic content was evaluated using the Folin-Ciocalteu technique. Results: All the extracts showed antioxidant potential as well as the phenolic content. Regardless of the harvesting year and methods of evaluation, the highest antioxidant activity and the total polyphenol content were observed for extracts prepared in undiluted methanol, obtained during one hour lasting extraction. Conclusion: The results of the studies have suggested that hop leaves can be a potential source of health-promoting antioxidants.
{"title":"Comparison of antioxidant activity of extracts of hop leaves harvested in different years","authors":"Anna Muzykiewicz, A. Nowak, Joanna Zielonka-Brzezicka, Katarzyna Florkowska, Wiktoria Duchnik, A. Klimowicz","doi":"10.2478/hepo-2019-0013","DOIUrl":"https://doi.org/10.2478/hepo-2019-0013","url":null,"abstract":"Summary Introduction: Hop (Humulus lupulus L.) is a common plant in Europe, with many beneficial health effects. In addition to the use in brewing, hops are a valuable source of active substances used in conventional and folk medicine, such as humulones and lupulones, as well as antioxidants, including phenolic compounds. Objective: The aim of the study was to evaluate and compare the antioxidant activity of alcoholic extracts of fresh hop leaves collected in 2017 and 2018. Material and methods: The raw material consisting of fresh hop leaves was extracted using ultrasound-assisted extraction. Methyl, ethyl and isopropyl alcohol at three concentrations were used as extractants. The antioxidant activity of extracts was determined using DPPH and FRAP methods. Total phenolic content was evaluated using the Folin-Ciocalteu technique. Results: All the extracts showed antioxidant potential as well as the phenolic content. Regardless of the harvesting year and methods of evaluation, the highest antioxidant activity and the total polyphenol content were observed for extracts prepared in undiluted methanol, obtained during one hour lasting extraction. Conclusion: The results of the studies have suggested that hop leaves can be a potential source of health-promoting antioxidants.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"65 1","pages":"1 - 9"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43435621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Adamczak, M. Dreger, K. Seidler-Łożykowska, K. Wielgus
Summary Fireweed (Epilobium angustifolium L., Onagraceae) is one of important medicinal plants used especially in the treatment of urogenital disorders, including benign prostatic hyperplasia (BPH) and prostatitis. The therapeutic effects of E. angustifolium extracts comprise antiproliferative, anti-inflammatory, immunomodulatory, antioxidant, and also antimicrobial activities. The aim of the present review was to provide the information on the botany, phytochemistry and traditional uses of E. angustifolium. This plant is a widespread circumboreal species of North America and Eurasia, tolerant in terms of habitat conditions, and often occupying man-made open habitats. Phytochemical studies on E. angustifolium resulted in the identification of about 250 different metabolites, including about 170 substances found for the first time in this plant in the last six years (2014–2019). Fireweed has an abundance of polyphenolic compounds, particularly ellagitannins. Oenothein B and quercetin-3-O-glucuronide are proposed as markers for the identification and standardization of the plant raw material. E. angustifolium exhibits significant phytochemical variability in relation to the geographical origin, plant part and time of harvest/vegetation phase. Survey of the ethnobotanical literature showed that the above-mentioned species has been widely used not only as a medicinal, but also as an edible, honey and decorative plant.
{"title":"Fireweed (Epilobium angustifolium L.): botany, phytochemistry and traditional uses. A review","authors":"A. Adamczak, M. Dreger, K. Seidler-Łożykowska, K. Wielgus","doi":"10.2478/hepo-2019-0018","DOIUrl":"https://doi.org/10.2478/hepo-2019-0018","url":null,"abstract":"Summary Fireweed (Epilobium angustifolium L., Onagraceae) is one of important medicinal plants used especially in the treatment of urogenital disorders, including benign prostatic hyperplasia (BPH) and prostatitis. The therapeutic effects of E. angustifolium extracts comprise antiproliferative, anti-inflammatory, immunomodulatory, antioxidant, and also antimicrobial activities. The aim of the present review was to provide the information on the botany, phytochemistry and traditional uses of E. angustifolium. This plant is a widespread circumboreal species of North America and Eurasia, tolerant in terms of habitat conditions, and often occupying man-made open habitats. Phytochemical studies on E. angustifolium resulted in the identification of about 250 different metabolites, including about 170 substances found for the first time in this plant in the last six years (2014–2019). Fireweed has an abundance of polyphenolic compounds, particularly ellagitannins. Oenothein B and quercetin-3-O-glucuronide are proposed as markers for the identification and standardization of the plant raw material. E. angustifolium exhibits significant phytochemical variability in relation to the geographical origin, plant part and time of harvest/vegetation phase. Survey of the ethnobotanical literature showed that the above-mentioned species has been widely used not only as a medicinal, but also as an edible, honey and decorative plant.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"65 1","pages":"51 - 63"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2478/hepo-2019-0018","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43838020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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