Summary Introduction: In 2020, the Institute of Natural Fibres and Medicinal Plants (INF&MP) implemented the contract No. 7/PW 1.2 – IWNiRZ Poznań/KCRZG/2020 for the performance of a research service under the long-term programme “Creating scientific foundations for biological progress and protection of plant genetic resources as a source of innovation and support for sustainable agriculture and safety food for country”. Objective: The aim of the research was to prepare passport and valorisation data for 33 accessions of flax (Linum usitatissimum L.) sown at the INF&MP Experimental Station in Pętkowo. Methods: The field experiment was conducted on 33 samples of flax seeds, which were sown on an area of 1.6 m2. Morphological features were presented by means of numerical data and their evaluation. The agricultural characteristics (numerical values and percentage of the collective pattern) and lengths of vegetation period were also presented. The evaluation of the performed characteristics of flax accessions was presented numerically and the data were given to the International Flax Database. Results: On the basis of paper documentation, the country of origin of the accessions, the type of genotypes by origin (landrace, variety) and the date of inclusion of the accessions in the flax collection were determined. The results of the characterization of morphological trials were as follows: the total plant length of the flax plants ranged from 51.4 cm (La Estanzuella 117) to 76.5 cm (WUKR 06-417) According to the methodology of the International Flax Database, the total plant length were short (28 accessions), medium short (3) and medium (1). Technical length was usually short (28 accessions) and medium short (4 accessions). Stem thickness for all accessions was medium: 1.6–2.5 mm. The length of the panicle was long only for the Opal variety, for 25 accessions - medium and short for 6 accessions. A number of bolls from panicle was: 9.1–30.8. The 1000 seed weight was low for 25 accessions of flax and very low for 8 genotypes of flax. Conclusions: Both studied vegetation periods were short in the following flax accessions: AC Linora, Manchwrian, Noralta and T-397. Flax genotype WUKR-846 (I2010/0031) should be deleted from the flax genetic resources collection and considered as worthless as breeding material. The WUKR 06-417 accession collected during the field expedition is distinguished by a high fibre content – 27%. The highest seed yield per plot was obtained from the cultivation of the following linseed flax cultivars: Redwood, AC Mc Duff, Norlin, Noralta and Jenny.
{"title":"Passport data and valorisation data of 33 accessions from the collection of genetic resources of the species Linum usitatissimum L.","authors":"G. Silska","doi":"10.2478/hepo-2020-0024","DOIUrl":"https://doi.org/10.2478/hepo-2020-0024","url":null,"abstract":"Summary Introduction: In 2020, the Institute of Natural Fibres and Medicinal Plants (INF&MP) implemented the contract No. 7/PW 1.2 – IWNiRZ Poznań/KCRZG/2020 for the performance of a research service under the long-term programme “Creating scientific foundations for biological progress and protection of plant genetic resources as a source of innovation and support for sustainable agriculture and safety food for country”. Objective: The aim of the research was to prepare passport and valorisation data for 33 accessions of flax (Linum usitatissimum L.) sown at the INF&MP Experimental Station in Pętkowo. Methods: The field experiment was conducted on 33 samples of flax seeds, which were sown on an area of 1.6 m2. Morphological features were presented by means of numerical data and their evaluation. The agricultural characteristics (numerical values and percentage of the collective pattern) and lengths of vegetation period were also presented. The evaluation of the performed characteristics of flax accessions was presented numerically and the data were given to the International Flax Database. Results: On the basis of paper documentation, the country of origin of the accessions, the type of genotypes by origin (landrace, variety) and the date of inclusion of the accessions in the flax collection were determined. The results of the characterization of morphological trials were as follows: the total plant length of the flax plants ranged from 51.4 cm (La Estanzuella 117) to 76.5 cm (WUKR 06-417) According to the methodology of the International Flax Database, the total plant length were short (28 accessions), medium short (3) and medium (1). Technical length was usually short (28 accessions) and medium short (4 accessions). Stem thickness for all accessions was medium: 1.6–2.5 mm. The length of the panicle was long only for the Opal variety, for 25 accessions - medium and short for 6 accessions. A number of bolls from panicle was: 9.1–30.8. The 1000 seed weight was low for 25 accessions of flax and very low for 8 genotypes of flax. Conclusions: Both studied vegetation periods were short in the following flax accessions: AC Linora, Manchwrian, Noralta and T-397. Flax genotype WUKR-846 (I2010/0031) should be deleted from the flax genetic resources collection and considered as worthless as breeding material. The WUKR 06-417 accession collected during the field expedition is distinguished by a high fibre content – 27%. The highest seed yield per plot was obtained from the cultivation of the following linseed flax cultivars: Redwood, AC Mc Duff, Norlin, Noralta and Jenny.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"66 1","pages":"32 - 42"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46019035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Zdanowski, B. Bałan, K. Schönknecht, P. Skopiński, M. Stelmasiak, E. Skopińska-Różewska, S. Lewicki
Abstract Introduction AAES is a powdered form of Biostymina, herbal medicinal product of Phytopharm Klęka S.A., a water extract of Aloe arborescens Mill. leaves. Aloe arborescens Mill. (woody aloe, tree-like aloe) is known to have several traditional medicinal properties including anti-inflammatory, immunomodulatory, antiviral and antimicrobial activity. Objective The aim of this work was to study the in vivo effect of AAES on cellular (leukocyte-induced cutaneous angiogenesis, LIA test, and proliferative response to PHA) and humoral (anti-SRBC antibody response) immunity in mice. Methods Balb/c mice were fed AAES from 0.5 to 75 mg/kg body mass for seven days before grafting their splenocytes intradermally to F1 (Balb/cxC3H) recipients (LIA test). Neovascular reaction was evaluated 72 h later in dissection microscope. Spleen cell cultures were incubated with 0.5, 1 and 2 μg/ml of PHA. After 48 h of incubation, tritiated thymidine was added. After further 24 h, cells were harvested (Skatron) and incorporation of tritiated thymidine was measured using Beta-scintillation counter. Balb/c mice were fed for 7 days with AAES, then immunized intraperitoneally with 5% SRBC suspension and 7 days later the antibody response was measured with hemagglutination test. Results Neovascular reaction was significantly higher in groups grafted with splenocytes collected from all AAES fed donors than from the controls. The proliferation of splenocytes taken from mice fed AAES at doses ranging from 0.5 mg/kg to 7.5 mg/kg was stimulated in all cultures. Suppression of proliferation was observed in cell cultures derived from mice fed with higher doses of AAES. Stimulation of anti-SRBC antibody production was seen in mice fed both 2.5 and 7.5 mg/kg dose of AAES. Conclusion Powdered form of Biostymina (AAES) might be useful in the treatment of patients with ischaemia of tissues and organs (myocardial infarction, stroke, necrosis) and in deficiency in the production of immune cells and growth factors (infections, chronic wound healing, ulceration and bone fusion).
{"title":"In vivo immuno - and angiomodulatory effects of Aloe arborescens folii recentis extractum siccum (AAES) in mice","authors":"R. Zdanowski, B. Bałan, K. Schönknecht, P. Skopiński, M. Stelmasiak, E. Skopińska-Różewska, S. Lewicki","doi":"10.2478/hepo-2020-0011","DOIUrl":"https://doi.org/10.2478/hepo-2020-0011","url":null,"abstract":"Abstract Introduction AAES is a powdered form of Biostymina, herbal medicinal product of Phytopharm Klęka S.A., a water extract of Aloe arborescens Mill. leaves. Aloe arborescens Mill. (woody aloe, tree-like aloe) is known to have several traditional medicinal properties including anti-inflammatory, immunomodulatory, antiviral and antimicrobial activity. Objective The aim of this work was to study the in vivo effect of AAES on cellular (leukocyte-induced cutaneous angiogenesis, LIA test, and proliferative response to PHA) and humoral (anti-SRBC antibody response) immunity in mice. Methods Balb/c mice were fed AAES from 0.5 to 75 mg/kg body mass for seven days before grafting their splenocytes intradermally to F1 (Balb/cxC3H) recipients (LIA test). Neovascular reaction was evaluated 72 h later in dissection microscope. Spleen cell cultures were incubated with 0.5, 1 and 2 μg/ml of PHA. After 48 h of incubation, tritiated thymidine was added. After further 24 h, cells were harvested (Skatron) and incorporation of tritiated thymidine was measured using Beta-scintillation counter. Balb/c mice were fed for 7 days with AAES, then immunized intraperitoneally with 5% SRBC suspension and 7 days later the antibody response was measured with hemagglutination test. Results Neovascular reaction was significantly higher in groups grafted with splenocytes collected from all AAES fed donors than from the controls. The proliferation of splenocytes taken from mice fed AAES at doses ranging from 0.5 mg/kg to 7.5 mg/kg was stimulated in all cultures. Suppression of proliferation was observed in cell cultures derived from mice fed with higher doses of AAES. Stimulation of anti-SRBC antibody production was seen in mice fed both 2.5 and 7.5 mg/kg dose of AAES. Conclusion Powdered form of Biostymina (AAES) might be useful in the treatment of patients with ischaemia of tissues and organs (myocardial infarction, stroke, necrosis) and in deficiency in the production of immune cells and growth factors (infections, chronic wound healing, ulceration and bone fusion).","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"66 1","pages":"13 - 23"},"PeriodicalIF":0.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46059046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Ballota nigra, also known as black horehound is a common medical herb used in folk medicine around the world. First reported mentions of its medical properties and use goes as far as the 13th century. The use of black horehound depends on regions and countries. It is used mostly to treat e.g. mild sleep disorders, nervousness, upset stomach, wound healing. It can be used as an anti-inflammatory, antibacterial, antiprotozoal, antifungal drug. Moreover, it has been reported as a potential cancer drug. This extensive usage is particularly interesting for us. The aim of this review is to present available data on B. nigra pharmacological effects and known traditional uses gathered from a wide range of scientific articles published in 1997–2020.
{"title":"Ballota nigra L. – an overview of pharmacological effects and traditional uses","authors":"Filip Przerwa, A. Kukowka, I. Uzar","doi":"10.2478/hepo-2020-0014","DOIUrl":"https://doi.org/10.2478/hepo-2020-0014","url":null,"abstract":"Abstract Ballota nigra, also known as black horehound is a common medical herb used in folk medicine around the world. First reported mentions of its medical properties and use goes as far as the 13th century. The use of black horehound depends on regions and countries. It is used mostly to treat e.g. mild sleep disorders, nervousness, upset stomach, wound healing. It can be used as an anti-inflammatory, antibacterial, antiprotozoal, antifungal drug. Moreover, it has been reported as a potential cancer drug. This extensive usage is particularly interesting for us. The aim of this review is to present available data on B. nigra pharmacological effects and known traditional uses gathered from a wide range of scientific articles published in 1997–2020.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"66 1","pages":"56 - 65"},"PeriodicalIF":0.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42043679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Fenugreek has a long tradition of use as a medicine and also has been commonly used as food in many countries. This plant is well known, especially in Asia. In Europe, fenugreek seeds are regarded as a traditional herbal medicine consumed in case of loss of appetite and in confirmed skin inflammations. Trigonella foenum-graecum seeds contain wide spectrum of different biologically active constituents which affect the properties of preparations produced from this plant. Numerous preclinical studies confirm the use of fenu-greek as a hypolipidemic and lowering blood glucose level drug. Unfortunately, there are not many clinical studies on fenugreek seeds in this area. Published studies often significantly differ in the amount and type of fenugreek seed preparation used. However, results of available scientific research are promising and suggest the possibility of using fenugreek seeds in metabolic syndrome therapy. Undoubtedly, further research is required to confirm such properties of Trigonella foenum-graecum.
{"title":"Trigonella foenum-graecum seeds in treatment of metabolic syndrome","authors":"Małgorzata Kania-Dobrowolska, Justyna Baraniak","doi":"10.2478/hepo-2020-0012","DOIUrl":"https://doi.org/10.2478/hepo-2020-0012","url":null,"abstract":"Abstract Fenugreek has a long tradition of use as a medicine and also has been commonly used as food in many countries. This plant is well known, especially in Asia. In Europe, fenugreek seeds are regarded as a traditional herbal medicine consumed in case of loss of appetite and in confirmed skin inflammations. Trigonella foenum-graecum seeds contain wide spectrum of different biologically active constituents which affect the properties of preparations produced from this plant. Numerous preclinical studies confirm the use of fenu-greek as a hypolipidemic and lowering blood glucose level drug. Unfortunately, there are not many clinical studies on fenugreek seeds in this area. Published studies often significantly differ in the amount and type of fenugreek seed preparation used. However, results of available scientific research are promising and suggest the possibility of using fenugreek seeds in metabolic syndrome therapy. Undoubtedly, further research is required to confirm such properties of Trigonella foenum-graecum.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"66 1","pages":"48 - 55"},"PeriodicalIF":0.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44163113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Introduction Fungal disseases are the most common opportunistic infection. Objective The main aims of the study were to determine phenolic content and to evaluate the antioxidant and anti-candida activity of the selected Indian-origin plant extracts from the fruit pulp, stem, leaves, and seeds of three plants of Indian origin. Material and methods The extracts from Terminalia chebula, Thuja occidentalic and Syzygium jambolanum were investigated. The total phenolic content, antioxidant potential of different crude extracts was accessed using the free radical, 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS). Anti-candida activity was evaluated using disk diffusion method and broth dilution assay against Candida albicans. Results Ethanol and methanol extracts of Indian traditional plants possessed high radical scavenging activity: T. chebula 29.38±0.15, T. occidentalis 6.26±0.24 and S. jambolanum 25.64±0.18 at 0.32 mg/ml. The extracts exhibited good zones of inhibition diameters ranged between: for T. chebula 6.33±0.57 mm and 19.66±1.52 mm in diameter, S. jambolanum 7.00±00 mm and 23.33±1.52 and T. occidentalis 7.66±0.57 and 17.00±1.00 mm. C. albicans were susceptible to all three tested extract at different concentrations. The lowest MIC 1.95 mg/ml was recorded with S. jambolanum while the T. chebula and T. occidentalis inhibited the growth at 3.90 mg/ml, respectively, against the C. albicans. Conclusion The study result paves an overall view on the bioactivities of three traditional Indian medicinal plants crude extracts.
{"title":"Antioxidant and anti-candida activity of selected medicinal plants of Indian origin","authors":"Suneel Prajapati, A. Bhardwaj, Pankaj Gupta","doi":"10.2478/hepo-2020-0016","DOIUrl":"https://doi.org/10.2478/hepo-2020-0016","url":null,"abstract":"Abstract Introduction Fungal disseases are the most common opportunistic infection. Objective The main aims of the study were to determine phenolic content and to evaluate the antioxidant and anti-candida activity of the selected Indian-origin plant extracts from the fruit pulp, stem, leaves, and seeds of three plants of Indian origin. Material and methods The extracts from Terminalia chebula, Thuja occidentalic and Syzygium jambolanum were investigated. The total phenolic content, antioxidant potential of different crude extracts was accessed using the free radical, 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS). Anti-candida activity was evaluated using disk diffusion method and broth dilution assay against Candida albicans. Results Ethanol and methanol extracts of Indian traditional plants possessed high radical scavenging activity: T. chebula 29.38±0.15, T. occidentalis 6.26±0.24 and S. jambolanum 25.64±0.18 at 0.32 mg/ml. The extracts exhibited good zones of inhibition diameters ranged between: for T. chebula 6.33±0.57 mm and 19.66±1.52 mm in diameter, S. jambolanum 7.00±00 mm and 23.33±1.52 and T. occidentalis 7.66±0.57 and 17.00±1.00 mm. C. albicans were susceptible to all three tested extract at different concentrations. The lowest MIC 1.95 mg/ml was recorded with S. jambolanum while the T. chebula and T. occidentalis inhibited the growth at 3.90 mg/ml, respectively, against the C. albicans. Conclusion The study result paves an overall view on the bioactivities of three traditional Indian medicinal plants crude extracts.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"66 1","pages":"1 - 12"},"PeriodicalIF":0.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42763240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Introduction Institute of Natural Fibres and Medicinal Plants (INF&MP) is involved in gathering and evaluation of genetic resources of flax (Linum usitatissimum L.), hemp (Cannabis sativa L.) and medicinal plants, because Poland has signed the Convention on Biological Diversity. Field trials were carried out in 1990–2001 in the Experimental Station in Wojciechów located in Opolskie region. The research material was accessions of genetic resources from the collection of flax, stored at the Institute of Plant Breeding and Acclimatization Institute in Radzików near Warsaw. Objective The aim of the publication was to evaluate the following biological features of flax: time of beginning of flowering and vegetation period to yellow maturity. Methods The characteristics data for flax accessions are presented according to the methodology of development of the International Flax Database. Each flax accessions from the world collection of flax genetic resources received one of the following assessments of two vegetation periods: very short, short, medium, long and very long. Descriptors of biological features of flax were used, presented in “List of flax descriptors (L. usitatissimum L.)” edited by Janka Nozkova, published in 2011. These descriptors are used to develop the International Flax Database, which in turn helps in the rapid evaluation of the L. usitatissimum genetic resource collection. Carrying out a detailed characterization of biological features of L. usitatissimum accessions is very helpful for breeders in selecting genetic material for breeding new varieties of flax. Results The following results were obtained from the time of the beginning of flowering and the vegetation period to yellow maturity. Time of beginning of flowering was the following: very short – 0 accessions, short – 97 accessions, medium – 20 accessions, long – 2 accessions and very long – 0 accessions of flax. The genotypes tested were characterized by the following results in terms of vegetation period from sowing to yellow maturity: very short – 0, short – 37, medium – 62, long – 0 and very long – 0 accessions of flax. Conclusions Time of beginning of flowering and the vegetation period to yellow maturity shall be revalorised to the International Flax Database for those L. usitatissimum accessions that did not receive the same assessment of the biological features tested in the two or three years of the study.
{"title":"Vegetation period of genetic resources of flax (Linum usitatissimum L.)","authors":"G. Silska","doi":"10.2478/hepo-2020-0017","DOIUrl":"https://doi.org/10.2478/hepo-2020-0017","url":null,"abstract":"Abstract Introduction Institute of Natural Fibres and Medicinal Plants (INF&MP) is involved in gathering and evaluation of genetic resources of flax (Linum usitatissimum L.), hemp (Cannabis sativa L.) and medicinal plants, because Poland has signed the Convention on Biological Diversity. Field trials were carried out in 1990–2001 in the Experimental Station in Wojciechów located in Opolskie region. The research material was accessions of genetic resources from the collection of flax, stored at the Institute of Plant Breeding and Acclimatization Institute in Radzików near Warsaw. Objective The aim of the publication was to evaluate the following biological features of flax: time of beginning of flowering and vegetation period to yellow maturity. Methods The characteristics data for flax accessions are presented according to the methodology of development of the International Flax Database. Each flax accessions from the world collection of flax genetic resources received one of the following assessments of two vegetation periods: very short, short, medium, long and very long. Descriptors of biological features of flax were used, presented in “List of flax descriptors (L. usitatissimum L.)” edited by Janka Nozkova, published in 2011. These descriptors are used to develop the International Flax Database, which in turn helps in the rapid evaluation of the L. usitatissimum genetic resource collection. Carrying out a detailed characterization of biological features of L. usitatissimum accessions is very helpful for breeders in selecting genetic material for breeding new varieties of flax. Results The following results were obtained from the time of the beginning of flowering and the vegetation period to yellow maturity. Time of beginning of flowering was the following: very short – 0 accessions, short – 97 accessions, medium – 20 accessions, long – 2 accessions and very long – 0 accessions of flax. The genotypes tested were characterized by the following results in terms of vegetation period from sowing to yellow maturity: very short – 0, short – 37, medium – 62, long – 0 and very long – 0 accessions of flax. Conclusions Time of beginning of flowering and the vegetation period to yellow maturity shall be revalorised to the International Flax Database for those L. usitatissimum accessions that did not receive the same assessment of the biological features tested in the two or three years of the study.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"66 1","pages":"36 - 47"},"PeriodicalIF":0.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42348238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Robert Ikechukwu Uroko, F. Adamude, S. Egba, C. N. Chukwu, C. L. Asadu, Emmanuel Chidera Okwara
Abstract Objective This study evaluated the effects of combined ethanol extract of Funtumia africana and Abutilon mauritianum leaves (FAAM) on the liver function indices of benign prostatic hyperplasia (BPH) induced rats. Materials and Methods The study used 30 rats divided into 5 groups, comprising normal control, BPH control, standard control, and BPH induced rats treated with 200 and 600 mg/kg/day of FAAM respectively. Results The BPH induction caused significant (p<0.05) increases in aspartate transaminase (AST) and alkaline phosphatase (ALP) activities of the BPH control when compared with the normal control. The BPH control also had significantly (p<0.05) reductions in the total protein, albumin and globulin concentrations and significant (p<0.05) elevated total bilirubin and direct bilirubin concentrations relative to the normal control. The FAAM treated BPH-induced rats had non-significantly (p>0.05) reduced AST, and alanine transaminase (ALT) activities relative to the BPH control. The BPH-induced rats treated with 600 mg/kg/day of FAAM had significantly (p<0.05) reduced ALP activities relative to the BPH control. Treatment with FAAM caused significant (p<0.05) increases in the total protein, albumin, globulin concentrations and significant (p<0.05) reductions in the total bilirubin and direct bilirubin concentrations relative to the BPH control. BPH had no observable adverse effects on the liver histomorphology of the rats. Conclusion The findings of this study indicated that BPH impairs liver functions and treatment of BPH with combined ethanol extract of F. africana and A. mauritianum leaves restore normal liver functions in rats with BPH.
{"title":"Effects of combined ethanol extract of Funtumia africana and Abutilon mauritianum leaves (FAAM) on liver function indices of benign prostatic hyperplasia (BPH) induced rats","authors":"Robert Ikechukwu Uroko, F. Adamude, S. Egba, C. N. Chukwu, C. L. Asadu, Emmanuel Chidera Okwara","doi":"10.2478/hepo-2020-0013","DOIUrl":"https://doi.org/10.2478/hepo-2020-0013","url":null,"abstract":"Abstract Objective This study evaluated the effects of combined ethanol extract of Funtumia africana and Abutilon mauritianum leaves (FAAM) on the liver function indices of benign prostatic hyperplasia (BPH) induced rats. Materials and Methods The study used 30 rats divided into 5 groups, comprising normal control, BPH control, standard control, and BPH induced rats treated with 200 and 600 mg/kg/day of FAAM respectively. Results The BPH induction caused significant (p<0.05) increases in aspartate transaminase (AST) and alkaline phosphatase (ALP) activities of the BPH control when compared with the normal control. The BPH control also had significantly (p<0.05) reductions in the total protein, albumin and globulin concentrations and significant (p<0.05) elevated total bilirubin and direct bilirubin concentrations relative to the normal control. The FAAM treated BPH-induced rats had non-significantly (p>0.05) reduced AST, and alanine transaminase (ALT) activities relative to the BPH control. The BPH-induced rats treated with 600 mg/kg/day of FAAM had significantly (p<0.05) reduced ALP activities relative to the BPH control. Treatment with FAAM caused significant (p<0.05) increases in the total protein, albumin, globulin concentrations and significant (p<0.05) reductions in the total bilirubin and direct bilirubin concentrations relative to the BPH control. BPH had no observable adverse effects on the liver histomorphology of the rats. Conclusion The findings of this study indicated that BPH impairs liver functions and treatment of BPH with combined ethanol extract of F. africana and A. mauritianum leaves restore normal liver functions in rats with BPH.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"66 1","pages":"24 - 35"},"PeriodicalIF":0.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44203462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Summary Pelargonium sidoides DC is an interesting plant with various biological properties. Pharmaceutical companies and manufacturers of food supplements are particularly interested in its beneficial effects in upper respiratory tract infections. The search for new therapeutic options is especially important at a time when antibiotics are prescribed too often. However, due to proven clinical effects of extracts from Pelargonium sidoides, their use in diet supplements, especially intended for infants and small children, is highly disputable. The paper presents reports on the use of Pelargonium sidoides extracts in paediatrics and also tries to answer the question whether the pelargonium extract should be qualified as food supplement or medicine.
{"title":"Pelargonium root (Pelargonium sidoides DC) extract in paediatric patients - food supplement or medicine?","authors":"Justyna Baraniak, Małgorzata Kania-Dobrowolska","doi":"10.2478/hepo-2020-0009","DOIUrl":"https://doi.org/10.2478/hepo-2020-0009","url":null,"abstract":"Summary Pelargonium sidoides DC is an interesting plant with various biological properties. Pharmaceutical companies and manufacturers of food supplements are particularly interested in its beneficial effects in upper respiratory tract infections. The search for new therapeutic options is especially important at a time when antibiotics are prescribed too often. However, due to proven clinical effects of extracts from Pelargonium sidoides, their use in diet supplements, especially intended for infants and small children, is highly disputable. The paper presents reports on the use of Pelargonium sidoides extracts in paediatrics and also tries to answer the question whether the pelargonium extract should be qualified as food supplement or medicine.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"66 1","pages":"28 - 33"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45868517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Summary Acquired immunodeficiency syndrome (AIDS) is an immunosuppressive disease caused by human immunodeficiency virus (HIV). The urgent need for searching novel anti-HIV/AIDS medicines is a global concern. So far, a lot of medicinal and aromatic plants (MAPs) have been analyzed to select those that could assist in the prevention and/or amelioration of the disease. Among biologically active compounds present in these plants, one of the most promising group are phenolics. The purpose of this article was to report anti-HIV activity of selected phenolic compounds of plant origin.
{"title":"Anti-HIV activity of some natural phenolics","authors":"M. El-Ansari, L. Ibrahim, M. Sharaf","doi":"10.2478/hepo-2020-0010","DOIUrl":"https://doi.org/10.2478/hepo-2020-0010","url":null,"abstract":"Summary Acquired immunodeficiency syndrome (AIDS) is an immunosuppressive disease caused by human immunodeficiency virus (HIV). The urgent need for searching novel anti-HIV/AIDS medicines is a global concern. So far, a lot of medicinal and aromatic plants (MAPs) have been analyzed to select those that could assist in the prevention and/or amelioration of the disease. Among biologically active compounds present in these plants, one of the most promising group are phenolics. The purpose of this article was to report anti-HIV activity of selected phenolic compounds of plant origin.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"66 1","pages":"34 - 43"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44924919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Muzykiewicz-Szymańska, Joanna Zielonka-Brzezicka, Joanna Siemak, A. Klimowicz
Summary Introduction: Due to the content of nutrients and taste attributes, the plant sprouts could become a valuable component of a healthy diet. Objective: The aim of the study was to evaluate the antioxidant potential of various sprouts extracts depending on the processing method of the plant material. Methods: The extracts in 96%(v/v) ethanol were prepared from fresh, frozen, dry and homogenized sprouts of alfalfa, broccoli, radish, lentil, mung bean, beetroot, sunflower, and kale, using ultrasound-assisted extraction. The antioxidant potential and total polyphenols content were evaluated by the in vitro methods. Results: The highest antioxidant activity was observed for beetroot and kale as well as broccoli sprouts extracts. The lower potential, in general, was observed in the case of alfalfa, lentil, and mung bean sprouts samples. The lowest activity was observed most frequently for the extracts from dry material, whereas the highest for homogenized as well as frozen and fresh. Conclusion: The plant sprouts, particularly beetroot, kale, and broccoli, could be a valuable source of natural antioxidants.
{"title":"Antioxidant activity of various plant sprouts extracts depending on the processing method of plant material – an in vitro study","authors":"Anna Muzykiewicz-Szymańska, Joanna Zielonka-Brzezicka, Joanna Siemak, A. Klimowicz","doi":"10.2478/hepo-2020-0006","DOIUrl":"https://doi.org/10.2478/hepo-2020-0006","url":null,"abstract":"Summary Introduction: Due to the content of nutrients and taste attributes, the plant sprouts could become a valuable component of a healthy diet. Objective: The aim of the study was to evaluate the antioxidant potential of various sprouts extracts depending on the processing method of the plant material. Methods: The extracts in 96%(v/v) ethanol were prepared from fresh, frozen, dry and homogenized sprouts of alfalfa, broccoli, radish, lentil, mung bean, beetroot, sunflower, and kale, using ultrasound-assisted extraction. The antioxidant potential and total polyphenols content were evaluated by the in vitro methods. Results: The highest antioxidant activity was observed for beetroot and kale as well as broccoli sprouts extracts. The lower potential, in general, was observed in the case of alfalfa, lentil, and mung bean sprouts samples. The lowest activity was observed most frequently for the extracts from dry material, whereas the highest for homogenized as well as frozen and fresh. Conclusion: The plant sprouts, particularly beetroot, kale, and broccoli, could be a valuable source of natural antioxidants.","PeriodicalId":12990,"journal":{"name":"Herba Polonica","volume":"66 1","pages":"11 - 18"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46194664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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