Pub Date : 2023-12-28DOI: 10.47470/0016-9900-2023-102-12-1266-1271
S. Shayakhmetov, A. Merinov, O. Zhurba, A. Alekseenko
Introduction. Environmental pollution leads to the need for regular monitoring and analysis of the content of toxic elements in the components of the environment and biosubstrates of the population to determine the degree of contamination of the territory, their accumulation in the body and assess the risk of health disorders. Materials and methods. Samples of snow cover were taken from eleven different sections of functional zones, and 52 hair samples were examined in two groups of children in different schools of the city. Determination of the content of water–soluble heavy metals and arsenic (HMAr) was carried out by atomic absorption method on the AAC-240 DUO “Agilent Technolgies” device. Results. In the snow cover of individual functional zones of Svirsk, a significant excess of Cu, Zn, Mn, Cd, Pb, and As content was found in comparison with background values in the range of 2–11 times. Indicator elements (Mn, Cr, Zn, Cd, As) reflecting the specifics of increased accumulation of HMAr in the hair of children in different areas of the city were identified. Strong correlations (r = 0.78–0.83) were established between the content of HMAr in the snow cover near schools and in the hair in the examined groups of children. Limitations. The assessment of content of HMs in the snow cover and in the hair in children population was evaluated without determining the accumulation of elements in the soil and migration to plant cultures. Conclusion. The revealed high levels of accumulation of HMAr in the snow cover and hair in children in Svirsk, due to the significant anthropogenic impact of emissions from industrial enterprises, motor vehicles, and residential households, indicate the tension of the environmental situation in the city and the need to implement a set of measures to improve it.
{"title":"Assessment of the content of heavy metals in the snow cover and hair in children","authors":"S. Shayakhmetov, A. Merinov, O. Zhurba, A. Alekseenko","doi":"10.47470/0016-9900-2023-102-12-1266-1271","DOIUrl":"https://doi.org/10.47470/0016-9900-2023-102-12-1266-1271","url":null,"abstract":"Introduction. Environmental pollution leads to the need for regular monitoring and analysis of the content of toxic elements in the components of the environment and biosubstrates of the population to determine the degree of contamination of the territory, their accumulation in the body and assess the risk of health disorders. Materials and methods. Samples of snow cover were taken from eleven different sections of functional zones, and 52 hair samples were examined in two groups of children in different schools of the city. Determination of the content of water–soluble heavy metals and arsenic (HMAr) was carried out by atomic absorption method on the AAC-240 DUO “Agilent Technolgies” device. Results. In the snow cover of individual functional zones of Svirsk, a significant excess of Cu, Zn, Mn, Cd, Pb, and As content was found in comparison with background values in the range of 2–11 times. Indicator elements (Mn, Cr, Zn, Cd, As) reflecting the specifics of increased accumulation of HMAr in the hair of children in different areas of the city were identified. Strong correlations (r = 0.78–0.83) were established between the content of HMAr in the snow cover near schools and in the hair in the examined groups of children. Limitations. The assessment of content of HMs in the snow cover and in the hair in children population was evaluated without determining the accumulation of elements in the soil and migration to plant cultures. Conclusion. The revealed high levels of accumulation of HMAr in the snow cover and hair in children in Svirsk, due to the significant anthropogenic impact of emissions from industrial enterprises, motor vehicles, and residential households, indicate the tension of the environmental situation in the city and the need to implement a set of measures to improve it.","PeriodicalId":13009,"journal":{"name":"Hygiene and sanitation","volume":"87 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139151845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-28DOI: 10.47470/0016-9900-2023-102-12-1327-1333
A. V. Ablyaeva, Lilia M. Fatkhutdinova
Introduction. Modern learning environment is a source of potential risk for the development of neurological problems among schoolchildren. The aim of this study is to analyze the influence of ergonomic factors of workplaces on the functional state of the nervous system in older adolescents in the modern educational environment. Materials and methods. The ergonomic assessment of workplaces in the school at the individual workplace was given; the study of subjective complaints from the nervous system in adolescents and related factors during the questionnaire survey of schoolchildren and parents. Indicators of the functional state of the nervous system in adolescents were evaluated using the method of M.P. Moroz. Results. Headache complaints are highly prevalent among adolescents. In the course of the study, we found that staying in an irrational working posture increases the likelihood of headaches among adolescents. In addition, the irrationality of the working posture and the mismatch of the size of educational furniture with the anthropometric data of adolescents, statistically significantly affect the on the change in the indicators of the functional state of the nervous system in adolescents. Limitations. Limitations of the study include the fact that the study included groups of 15–16-year adolescents. The study is also limited by the fact that it was cross-sectional in nature. Studies investigating the influence of school ergonomic factors on the state of the nervous system of schoolchildren in dynamics may be promising. Conclusion. To prevent damage to the nervous system, it is important to observe ergonomic principles, teach adolescents to maintain a rational working posture in school.
{"title":"Influence of ergonomic parameters of schoolchildren’s workplaces on the functional state of the nervous system in adolescents","authors":"A. V. Ablyaeva, Lilia M. Fatkhutdinova","doi":"10.47470/0016-9900-2023-102-12-1327-1333","DOIUrl":"https://doi.org/10.47470/0016-9900-2023-102-12-1327-1333","url":null,"abstract":"Introduction. Modern learning environment is a source of potential risk for the development of neurological problems among schoolchildren. The aim of this study is to analyze the influence of ergonomic factors of workplaces on the functional state of the nervous system in older adolescents in the modern educational environment. Materials and methods. The ergonomic assessment of workplaces in the school at the individual workplace was given; the study of subjective complaints from the nervous system in adolescents and related factors during the questionnaire survey of schoolchildren and parents. Indicators of the functional state of the nervous system in adolescents were evaluated using the method of M.P. Moroz. Results. Headache complaints are highly prevalent among adolescents. In the course of the study, we found that staying in an irrational working posture increases the likelihood of headaches among adolescents. In addition, the irrationality of the working posture and the mismatch of the size of educational furniture with the anthropometric data of adolescents, statistically significantly affect the on the change in the indicators of the functional state of the nervous system in adolescents. Limitations. Limitations of the study include the fact that the study included groups of 15–16-year adolescents. The study is also limited by the fact that it was cross-sectional in nature. Studies investigating the influence of school ergonomic factors on the state of the nervous system of schoolchildren in dynamics may be promising. Conclusion. To prevent damage to the nervous system, it is important to observe ergonomic principles, teach adolescents to maintain a rational working posture in school.","PeriodicalId":13009,"journal":{"name":"Hygiene and sanitation","volume":"67 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139151827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-28DOI: 10.47470/0016-9900-2023-102-12-1286-1291
E. A. Preobrazhenskaya, A. Sukhova, I. Yatsyna
Introduction. Predicting occupational hearing loss is a promising direction in the health protection of industrial workers. The purpose of the study is to develop and test a methodology for assessing the probability of hearing loss caused by noise, taking into account quantitative criteria for assessing the degree of hearing loss adopted in the Russian Federation. Materials and methods. The assessment of the probability of hearing loss caused by noise is carried out in accordance with GOST R ISO 1999–2017 and includes the determination of age, noise, and general hearing loss. To quantify the degree of hearing loss, a combination of audiometric frequencies of 500, 1000, 2000, 4000 Hz is used in accordance with the classification of the degree of hearing loss caused by noise. The probability of occupational hearing loss caused by noise (%) is determined by plotting the distribution of probabilistic hearing thresholds due to age and noise for the corresponding percentiles (10, 50, 90%). Results. The developed methodology complements and specifies the requirements of GOST R ISO 1999-2017 with respect to the combination of audiometric frequencies, according to which the probability of hearing loss caused by noise is assessed. The boundary thresholds of audibility, the excess of which indicates the presence of a certain degree of hearing loss. Based on the developed methodology, the probabilistic thresholds of audibility at noise exposure of 85, 90, 95, 100 dBA are calculated. The probability of occuptional hearing loss is determined depending on age, work experience, and noise exposure. Limitations. The limitations of the study are determined by the features of the model for assessing hearing loss due to noise exposure according to GOST ISO 1999–2017 and the criteria for assessing the degree of hearing loss in noise workers at audiometric frequencies of 500, 1000, 2000, 4000 Hz. Conclusion. The developed algorithm will make it possible to determine the probability of hearing loss caused by noise, predict the timing of the development of occupational hearing loss depending on the intensity and duration of noise exposure, the age of the employee, and develop risk-oriented preventive programs.
导言。预测职业性听力损失是保护产业工人健康的一个有前途的方向。 本研究的目的是根据俄罗斯联邦采用的听力损失程度量化评估标准,制定并测试评估噪声导致听力损失概率的方法。 材料和方法。噪声导致听力损失概率的评估按照 GOST R ISO 1999-2017 标准进行,包括年龄、噪声和一般听力损失的测定。为了量化听力损失程度,根据噪声导致听力损失程度的分类,使用了 500、1000、2000 和 4000 Hz 的测听频率组合。通过绘制相应百分位数(10%、50%、90%)的年龄和噪声导致的听阈概率分布图,确定噪声导致职业性听力损失的概率(%)。 结果。所开发的方法补充并明确了 GOST R ISO 1999-2017 中有关测听频率组合的要求,根据这些频率组合来评估噪声导致听力损失的概率。可听度的边界阈值,超过该阈值表明存在一定程度的听力损失。根据开发的方法,计算出噪音暴露在 85、90、95 和 100 dBA 时的可听度概率阈值。职业性听力损失的概率取决于年龄、工作经验和噪声暴露。 局限性。该研究的局限性取决于根据 GOST ISO 1999-2017 评估噪声暴露所致听力损失模型的特点,以及在听力测定频率为 500、1000、2000 和 4000 Hz 时评估噪声工人听力损失程度的标准。 结论通过所开发的算法,可以确定噪声导致听力损失的概率,根据噪声暴露的强度和持续时间、员工年龄预测职业性听力损失的发展时间,并制定以风险为导向的预防计划。
{"title":"Methodology for assessing the probability of hearing loss caused by noise","authors":"E. A. Preobrazhenskaya, A. Sukhova, I. Yatsyna","doi":"10.47470/0016-9900-2023-102-12-1286-1291","DOIUrl":"https://doi.org/10.47470/0016-9900-2023-102-12-1286-1291","url":null,"abstract":"Introduction. Predicting occupational hearing loss is a promising direction in the health protection of industrial workers. The purpose of the study is to develop and test a methodology for assessing the probability of hearing loss caused by noise, taking into account quantitative criteria for assessing the degree of hearing loss adopted in the Russian Federation. Materials and methods. The assessment of the probability of hearing loss caused by noise is carried out in accordance with GOST R ISO 1999–2017 and includes the determination of age, noise, and general hearing loss. To quantify the degree of hearing loss, a combination of audiometric frequencies of 500, 1000, 2000, 4000 Hz is used in accordance with the classification of the degree of hearing loss caused by noise. The probability of occupational hearing loss caused by noise (%) is determined by plotting the distribution of probabilistic hearing thresholds due to age and noise for the corresponding percentiles (10, 50, 90%). Results. The developed methodology complements and specifies the requirements of GOST R ISO 1999-2017 with respect to the combination of audiometric frequencies, according to which the probability of hearing loss caused by noise is assessed. The boundary thresholds of audibility, the excess of which indicates the presence of a certain degree of hearing loss. Based on the developed methodology, the probabilistic thresholds of audibility at noise exposure of 85, 90, 95, 100 dBA are calculated. The probability of occuptional hearing loss is determined depending on age, work experience, and noise exposure. Limitations. The limitations of the study are determined by the features of the model for assessing hearing loss due to noise exposure according to GOST ISO 1999–2017 and the criteria for assessing the degree of hearing loss in noise workers at audiometric frequencies of 500, 1000, 2000, 4000 Hz. Conclusion. The developed algorithm will make it possible to determine the probability of hearing loss caused by noise, predict the timing of the development of occupational hearing loss depending on the intensity and duration of noise exposure, the age of the employee, and develop risk-oriented preventive programs.","PeriodicalId":13009,"journal":{"name":"Hygiene and sanitation","volume":"304 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139152365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-28DOI: 10.47470/0016-9900-2023-102-12-1375-1380
N. V. Efimova, Marina V. Kuzmina, Elena V. Bobkova
Introduction. Ambient air pollution determines high levels of risk to public health, causing excess mortality. The purpose of the study is to analyze the dependence of the seasonal dynamics of pollutants and mortality from major non-infectious diseases in the population of the industrial center of Eastern Siberia. Materials and methods. Air pollution in Bratsk was assessed based on data from monitoring systems for 2017–2022, taking into account one-time, average monthly and annual concentrations. Hazard indices and mortality rates (MR) from major causes were calculated. The annual trend in indicators are assessed using seasonality indices (SI). Results. Features of the seasonal dynamics of pollutants were revealed: maximum fluctuations in SI are characteristic of benzo(a)pyrene (22% in the warm season, 214% in the cold season), formaldehyde (219 and 65%, respectively). The SI for mortality had significant fluctuations throughout the year and varied across age groups and disease classes. Changes in seasonality have been noted during the COVID-19 pandemic. Average monthly MR in the older group is associated with concentrations of PM2.5, formaldehyde, NO2. Limitations of the study are related to the limited data on monitoring pollutants, inevitable errors in conditional division into seasons, and the impossibility of accurately determining the cause of death during a pandemic. Conclusion. The use of average monthly data on MR values and pollutant concentrations confirms the dependence of population mortality on air pollution when studying this phenomenon in medium-sized cities with high levels of hazard indices.
{"title":"Assessment of the annual trend of chemical aerogenic risk to health and mortality of the population at an industrial center","authors":"N. V. Efimova, Marina V. Kuzmina, Elena V. Bobkova","doi":"10.47470/0016-9900-2023-102-12-1375-1380","DOIUrl":"https://doi.org/10.47470/0016-9900-2023-102-12-1375-1380","url":null,"abstract":"Introduction. Ambient air pollution determines high levels of risk to public health, causing excess mortality. The purpose of the study is to analyze the dependence of the seasonal dynamics of pollutants and mortality from major non-infectious diseases in the population of the industrial center of Eastern Siberia. Materials and methods. Air pollution in Bratsk was assessed based on data from monitoring systems for 2017–2022, taking into account one-time, average monthly and annual concentrations. Hazard indices and mortality rates (MR) from major causes were calculated. The annual trend in indicators are assessed using seasonality indices (SI). Results. Features of the seasonal dynamics of pollutants were revealed: maximum fluctuations in SI are characteristic of benzo(a)pyrene (22% in the warm season, 214% in the cold season), formaldehyde (219 and 65%, respectively). The SI for mortality had significant fluctuations throughout the year and varied across age groups and disease classes. Changes in seasonality have been noted during the COVID-19 pandemic. Average monthly MR in the older group is associated with concentrations of PM2.5, formaldehyde, NO2. Limitations of the study are related to the limited data on monitoring pollutants, inevitable errors in conditional division into seasons, and the impossibility of accurately determining the cause of death during a pandemic. Conclusion. The use of average monthly data on MR values and pollutant concentrations confirms the dependence of population mortality on air pollution when studying this phenomenon in medium-sized cities with high levels of hazard indices.","PeriodicalId":13009,"journal":{"name":"Hygiene and sanitation","volume":"16 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139150061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-28DOI: 10.47470/0016-9900-2023-102-12-1309-1314
V. A. Shirokov, N. Terekhov, A. V. Potaturko
Introduction. The pain in the lower back (BCC) has a wide distribution among the working people’s age and is a frequent cause of temporary disability. The identification of risk factors for the back pain is necessary to address expert issues and developing measures for prevention of incidence. Materials and methods. There were studied prevalence odds ratio (OR) for the development of the low back pain (LBP) in two thousand nine hundred fifteen working patients with different indicators of hardness of the labour process and levels of physical activity (PA). Results. According to the special assessment of the working conditions, the harmful (3rd) class of hardness of the labour process in comparison with the 1st and 2nd classes (optimal and permissible) increased the LBP prevalence from 31.6 to 37.1% with OR = 1.27 at 95% Ci (1.03–1.43), p <0.05. No reliable differences were obtained under comparing classes separately with the 1st class. According to the International questionnaire of physical activity, the LBP prevalence under an intensive PA is 29.3% with OR = 1.5 at 95% CI (1.6–2.11), at a low PA – 37.2% with OR = 2.15 at 95% Ci (1.07–4.3). The smallest LBP prevalence was revealed in a moderate PA mode throughout the day (21.6%). Limitations. The present study has a limitation associated with the inconsistency of cards for special assessment of working conditions and the International questionnaire cards. Conclusion. Data were obtained about the absence of reliable differences in the distribution and odds ratio for the development of LBP between workers by classes of hardness of the labour process. Workers with moderate and low PA have reliably low LBP prevalence.
简介下背部疼痛(BCC)在工作年龄段的人群中分布广泛,是导致暂时性残疾的常见原因。 要解决专家提出的问题并制定预防发病的措施,就必须确定腰痛的危险因素。 材料和方法。研究了 2 915 名劳动患者腰背痛(LBP)发病率的几率比(OR),这些患者的劳动强度和体力活动(PA)水平有不同的指标。 结果。根据对工作条件的特殊评估,与第一级和第二级(最佳和允许)相比,有害(第三级)的劳动过程硬度使腰背痛的发病率从 31.6% 上升到 37.1%,OR = 1.27,95% Ci (1.03-1.43),P <0.05。将各班级与第一班级分别进行比较,未发现可靠的差异。根据国际体力活动调查问卷,高强度体力活动的枸杞痛患病率为 29.3%,OR = 1.5,95% Ci (1.6-2.11);低强度体力活动的患病率为 37.2%,OR = 2.15,95% Ci (1.07-4.3)。全天中度活动量模式的枸杞痛发生率最小(21.6%)。 局限性。本研究的局限性在于工作条件特别评估卡与国际问卷卡不一致。 结论。本研究获得的数据表明,不同劳动强度的工人患腰椎间盘突出症的分布和几率没有可靠的差异。中度和低度劳动强度工人的枸杞多糖症发病率较低。
{"title":"The role of physical overstrain and hypodynamia in the development of the low back pain","authors":"V. A. Shirokov, N. Terekhov, A. V. Potaturko","doi":"10.47470/0016-9900-2023-102-12-1309-1314","DOIUrl":"https://doi.org/10.47470/0016-9900-2023-102-12-1309-1314","url":null,"abstract":"Introduction. The pain in the lower back (BCC) has a wide distribution among the working people’s age and is a frequent cause of temporary disability. The identification of risk factors for the back pain is necessary to address expert issues and developing measures for prevention of incidence. Materials and methods. There were studied prevalence odds ratio (OR) for the development of the low back pain (LBP) in two thousand nine hundred fifteen working patients with different indicators of hardness of the labour process and levels of physical activity (PA). Results. According to the special assessment of the working conditions, the harmful (3rd) class of hardness of the labour process in comparison with the 1st and 2nd classes (optimal and permissible) increased the LBP prevalence from 31.6 to 37.1% with OR = 1.27 at 95% Ci (1.03–1.43), p <0.05. No reliable differences were obtained under comparing classes separately with the 1st class. According to the International questionnaire of physical activity, the LBP prevalence under an intensive PA is 29.3% with OR = 1.5 at 95% CI (1.6–2.11), at a low PA – 37.2% with OR = 2.15 at 95% Ci (1.07–4.3). The smallest LBP prevalence was revealed in a moderate PA mode throughout the day (21.6%). Limitations. The present study has a limitation associated with the inconsistency of cards for special assessment of working conditions and the International questionnaire cards. Conclusion. Data were obtained about the absence of reliable differences in the distribution and odds ratio for the development of LBP between workers by classes of hardness of the labour process. Workers with moderate and low PA have reliably low LBP prevalence.","PeriodicalId":13009,"journal":{"name":"Hygiene and sanitation","volume":"3 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139150717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-28DOI: 10.47470/0016-9900-2023-102-12-1381-1388
Nina V. Zaytseva, T. Nurislamova, T. D. Karnazhitskaya, Mariya O. Starchikova
Introduction. The polycyclic aromatic hydrocarbons (PAH) refer to the group of priority environmental pollutants that enter the human body by inhalation, orally, through the skin, causing a long-term impact on metabolic processes, chronic and oncological diseases. To assess the impact of polycyclic aromatic hydrocarbons on the health of the population, it is actual to evaluate their content in human biological media. The purpose of the study is to develop and apply a methodology for determining the polycyclic aromatic hydrocarbons (naphthalene, 2-methylnaphthalene, anthracene, the 9-methylanthracene, pyrene and benz (a) pyrene) in the blood by a method of highly efficient liquid chromatography with fluoremetric detection (HPLC-FDD) for social and hygienic monitoring problems. Materials and methods. The object of research was biological media (blood samples). Studies on the development of the technique were carried out on the Shimadzu liquid chromatograph with a fluoremetric detector RF-20A. The approximation of the technique was carried out within the framework of deeper studies of children health in residents in territories with various exposure levels. Results. The conditions for sample production and parameters of the chromatographic analysis of blood PAH by the HPLC / FDD method were established. The degree of extraction of PAH from the blood by the method of liquid extraction was 77-100%. The analysis of blood PAH showed average group concentrations to be reliably higher (p <0.05) in the biological media in children living in the zone of influence of emissions of industrial enterprises. Priority compounds detected in the blood of the students are pyrene, naphthalene, 2-methylnaphthalene, Limitations are due to the period of selection of biological media of the different age groups in the territories of the Russian Federation with various levels of exposure. The expansion of the list of the populations can become a direction of further research on assessing the impact of polycyclic aromatic hydrocarbons on human health. Conclusion. The developed methodology can be used in hygienic studies for assessing the risk of conditions of exposure to polycyclic aromatic hydrocarbons for health of residents in the territories with different anthropogenic loads.
{"title":"Quantitative determination of polycyclic aromatic hydrocarbons in the blood by high-performance liquid chromatography with fluorimetric detection for the tasks of socio-hygienic monitoring","authors":"Nina V. Zaytseva, T. Nurislamova, T. D. Karnazhitskaya, Mariya O. Starchikova","doi":"10.47470/0016-9900-2023-102-12-1381-1388","DOIUrl":"https://doi.org/10.47470/0016-9900-2023-102-12-1381-1388","url":null,"abstract":"Introduction. The polycyclic aromatic hydrocarbons (PAH) refer to the group of priority environmental pollutants that enter the human body by inhalation, orally, through the skin, causing a long-term impact on metabolic processes, chronic and oncological diseases. To assess the impact of polycyclic aromatic hydrocarbons on the health of the population, it is actual to evaluate their content in human biological media. The purpose of the study is to develop and apply a methodology for determining the polycyclic aromatic hydrocarbons (naphthalene, 2-methylnaphthalene, anthracene, the 9-methylanthracene, pyrene and benz (a) pyrene) in the blood by a method of highly efficient liquid chromatography with fluoremetric detection (HPLC-FDD) for social and hygienic monitoring problems. Materials and methods. The object of research was biological media (blood samples). Studies on the development of the technique were carried out on the Shimadzu liquid chromatograph with a fluoremetric detector RF-20A. The approximation of the technique was carried out within the framework of deeper studies of children health in residents in territories with various exposure levels. Results. The conditions for sample production and parameters of the chromatographic analysis of blood PAH by the HPLC / FDD method were established. The degree of extraction of PAH from the blood by the method of liquid extraction was 77-100%. The analysis of blood PAH showed average group concentrations to be reliably higher (p <0.05) in the biological media in children living in the zone of influence of emissions of industrial enterprises. Priority compounds detected in the blood of the students are pyrene, naphthalene, 2-methylnaphthalene, Limitations are due to the period of selection of biological media of the different age groups in the territories of the Russian Federation with various levels of exposure. The expansion of the list of the populations can become a direction of further research on assessing the impact of polycyclic aromatic hydrocarbons on human health. Conclusion. The developed methodology can be used in hygienic studies for assessing the risk of conditions of exposure to polycyclic aromatic hydrocarbons for health of residents in the territories with different anthropogenic loads.","PeriodicalId":13009,"journal":{"name":"Hygiene and sanitation","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139151621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-28DOI: 10.47470/0016-9900-2023-102-12-1354-1360
O.G. Bogdanova
Introduction. In recent decades, the prevalence of nutritionally-dependent diseases has acquired the effect of globalization, which in general causes an increase in deaths from chronic non-communicable diseases and the emergence of socio-economic damage. The aim of the study is to assess the socio-economic damage caused by non-communicable nutritionally-dependent diseases among the population of the Republic of Buryatia. Materials and methods. The mortality rates of the population of the Republic of Buryatia due to non-communicable nutritionally-dependent diseases over 2011–2020 have been studied. Based on the principle of potential demography, social and economic damage due to premature mortality from these causes is calculated. Results. It was shown that share of the mortality from alimentary-dependent pathology in the Republic of Buryatia accounted for20.80% (20.54; 21.05) of all the mortality of the able-bodied population. Social losses annually averaged 52586.80 (50314.48; 54859.12) of non-lived person-years to the end of working age. Associated probable economic losses in the aggregate for the specified period from 33779.65 to 56299.42 million rubles. Conclusion. The analysis carried out in this work showed not only the significance of demographic losses from non-communicable nutritionally-dependent diseases, but also the significance of socio-economic damage. Together, this serves as objective evidence of the justified need for financial obligations to protect and promote the health of the population of the Republic of Buryatia to reduce the prevalence of risk factors through the prism of increasing awareness of a healthy lifestyle, including the principles of optimal nutrition. Limitations. The results of this study are due only to direct socio-economic losses, excluding indirect losses, which requires further research.
{"title":"Socio-economic damage caused by nutritionally-dependent diseases of the population","authors":"O.G. Bogdanova","doi":"10.47470/0016-9900-2023-102-12-1354-1360","DOIUrl":"https://doi.org/10.47470/0016-9900-2023-102-12-1354-1360","url":null,"abstract":"Introduction. In recent decades, the prevalence of nutritionally-dependent diseases has acquired the effect of globalization, which in general causes an increase in deaths from chronic non-communicable diseases and the emergence of socio-economic damage. The aim of the study is to assess the socio-economic damage caused by non-communicable nutritionally-dependent diseases among the population of the Republic of Buryatia. Materials and methods. The mortality rates of the population of the Republic of Buryatia due to non-communicable nutritionally-dependent diseases over 2011–2020 have been studied. Based on the principle of potential demography, social and economic damage due to premature mortality from these causes is calculated. Results. It was shown that share of the mortality from alimentary-dependent pathology in the Republic of Buryatia accounted for20.80% (20.54; 21.05) of all the mortality of the able-bodied population. Social losses annually averaged 52586.80 (50314.48; 54859.12) of non-lived person-years to the end of working age. Associated probable economic losses in the aggregate for the specified period from 33779.65 to 56299.42 million rubles. Conclusion. The analysis carried out in this work showed not only the significance of demographic losses from non-communicable nutritionally-dependent diseases, but also the significance of socio-economic damage. Together, this serves as objective evidence of the justified need for financial obligations to protect and promote the health of the population of the Republic of Buryatia to reduce the prevalence of risk factors through the prism of increasing awareness of a healthy lifestyle, including the principles of optimal nutrition. Limitations. The results of this study are due only to direct socio-economic losses, excluding indirect losses, which requires further research.","PeriodicalId":13009,"journal":{"name":"Hygiene and sanitation","volume":"42 36","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139151175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-28DOI: 10.47470/0016-9900-2023-102-12-1292-1296
E. Bakhtereva, E.L. Leiderman, T.A. Riabkova
Introduction. Early detection of functional changes in the nervous system makes it possible to clarify the etiopathogenetic effect of a whole set of adverse industrial factors, form a group at risk of occupational diseases, and develop preventive programs for given the main structural targets. The purpose of the study was to identify characteristics of functional disorders of the peripheral nervous systems in metallurgists exposed to occupational hazards. Materials and methods. We examined two cohorts of workers: a control cohort of forty men unexposed to occupational risk factors and a case cohort of 60 male employees of a metallurgical plant situated in the Sverdlovsk Region. The cohorts were matched by age (mean: 38.8±7.6 years) and work experience (5.1±4.7 years). The mean duration of exposure to occupational hazards was 7.1±6.0 years. We included 38 cases in the program of in-depth neurophysiological examination that consisted of assessment of neurological status, electroneuromyography (ENMG). Results. 73.9 % of the cases had no complaints. Functional disorders of peripheral nerves were diagnosed as distal polyneuropathy of the upper and lower extremities (47.4 %), median neuropathy (42.1 %), ulnar neuropathy (23.7 %), and radiculopathies (9.6 %). Noteworthy is the presence of additional damages of the median nerve at the carpal tunnel in 55.6 % of the cases having signs of distal polyneuropathy. Conclusions. A comprehensive neurophysiological examination, not required by the current order for periodic medical examinations, helps to identify dysfunctions of the nervous system at their early stages. It is necessary to form high-risk groups of patients to monitor the development of work-related nervous diseases.
{"title":"Functional disorders of the peripheral nervous system in metallurgical workers","authors":"E. Bakhtereva, E.L. Leiderman, T.A. Riabkova","doi":"10.47470/0016-9900-2023-102-12-1292-1296","DOIUrl":"https://doi.org/10.47470/0016-9900-2023-102-12-1292-1296","url":null,"abstract":"Introduction. Early detection of functional changes in the nervous system makes it possible to clarify the etiopathogenetic effect of a whole set of adverse industrial factors, form a group at risk of occupational diseases, and develop preventive programs for given the main structural targets. The purpose of the study was to identify characteristics of functional disorders of the peripheral nervous systems in metallurgists exposed to occupational hazards. Materials and methods. We examined two cohorts of workers: a control cohort of forty men unexposed to occupational risk factors and a case cohort of 60 male employees of a metallurgical plant situated in the Sverdlovsk Region. The cohorts were matched by age (mean: 38.8±7.6 years) and work experience (5.1±4.7 years). The mean duration of exposure to occupational hazards was 7.1±6.0 years. We included 38 cases in the program of in-depth neurophysiological examination that consisted of assessment of neurological status, electroneuromyography (ENMG). Results. 73.9 % of the cases had no complaints. Functional disorders of peripheral nerves were diagnosed as distal polyneuropathy of the upper and lower extremities (47.4 %), median neuropathy (42.1 %), ulnar neuropathy (23.7 %), and radiculopathies (9.6 %). Noteworthy is the presence of additional damages of the median nerve at the carpal tunnel in 55.6 % of the cases having signs of distal polyneuropathy. Conclusions. A comprehensive neurophysiological examination, not required by the current order for periodic medical examinations, helps to identify dysfunctions of the nervous system at their early stages. It is necessary to form high-risk groups of patients to monitor the development of work-related nervous diseases.","PeriodicalId":13009,"journal":{"name":"Hygiene and sanitation","volume":"59 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139150707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-28DOI: 10.47470/0016-9900-2023-102-12-1361-1366
Anastasiya A. Tsareva, Olga V. Egorova, Yuliya V. Demidova, N. A. Ilyushina
Introduction. Titanium dioxide in the Russian Federation is approved for use in the food industry, in the production of medicines and hygiene products. The food additive E171 is a mixture of micro- and nanoparticles of TiO2. In 2010, IARC classified TiO2 in nanoform as a probably carcinogenic to humans (Group 2B). In vitro and in vivo studies of the genotoxicity of titanium dioxide revealed contradictory results, indicating both the presence and absence of TiO2 mutagenicity. The aim of the work is to evaluate the mutagenicity of the food additive E171 in the Ames test using standard and modified protocols. Materials and methods. The ability of food additive E171 (China) to induce reverse gene mutations in 5 strains of Salmonella typhimurium was studied under standard and modified conditions (cultivation of bacteria in the presence of methylated b-cyclodextrin (MCD) and/or pre-incubation for 1 hour in potassium phosphate buffer, pH 5.5 containing 10 mM NaCl and/or 3M MCD). Results. A sample of food additive E171 based on rutile titanium dioxide does not induce gene mutations in S. typhimurium in standard experiments. Modification of the Ames test protocol (decrease of the incubation mixture pH, addition of 10 mM NaCl) revealed statistically significant dose-dependent effects in TA100, TA98, and TA97 strains under metabolic incubation conditions. However, the fold increase of the number of revertants in the experimental plates compared to the negative control was < 2. Limitations. The research is limited to the mutagenicity assessment of food additive E171 (titanium dioxide) in the Ames test. Conclusion. The evaluation of the mutagenicity of titanium dioxide in other in vitro and in vivo tests taking into account the size and shape of the particles, is necessary to resolve the issue of its genetic safety as a food dye. A full range of studies will be performed on other samples of titanium dioxide presented in the market of the Russian Federation.
{"title":"Studying the ability of the food additive E171 (titanium dioxide) to induce gene mutations in bacteria","authors":"Anastasiya A. Tsareva, Olga V. Egorova, Yuliya V. Demidova, N. A. Ilyushina","doi":"10.47470/0016-9900-2023-102-12-1361-1366","DOIUrl":"https://doi.org/10.47470/0016-9900-2023-102-12-1361-1366","url":null,"abstract":"Introduction. Titanium dioxide in the Russian Federation is approved for use in the food industry, in the production of medicines and hygiene products. The food additive E171 is a mixture of micro- and nanoparticles of TiO2. In 2010, IARC classified TiO2 in nanoform as a probably carcinogenic to humans (Group 2B). In vitro and in vivo studies of the genotoxicity of titanium dioxide revealed contradictory results, indicating both the presence and absence of TiO2 mutagenicity. The aim of the work is to evaluate the mutagenicity of the food additive E171 in the Ames test using standard and modified protocols. Materials and methods. The ability of food additive E171 (China) to induce reverse gene mutations in 5 strains of Salmonella typhimurium was studied under standard and modified conditions (cultivation of bacteria in the presence of methylated b-cyclodextrin (MCD) and/or pre-incubation for 1 hour in potassium phosphate buffer, pH 5.5 containing 10 mM NaCl and/or 3M MCD). Results. A sample of food additive E171 based on rutile titanium dioxide does not induce gene mutations in S. typhimurium in standard experiments. Modification of the Ames test protocol (decrease of the incubation mixture pH, addition of 10 mM NaCl) revealed statistically significant dose-dependent effects in TA100, TA98, and TA97 strains under metabolic incubation conditions. However, the fold increase of the number of revertants in the experimental plates compared to the negative control was < 2. Limitations. The research is limited to the mutagenicity assessment of food additive E171 (titanium dioxide) in the Ames test. Conclusion. The evaluation of the mutagenicity of titanium dioxide in other in vitro and in vivo tests taking into account the size and shape of the particles, is necessary to resolve the issue of its genetic safety as a food dye. A full range of studies will be performed on other samples of titanium dioxide presented in the market of the Russian Federation.","PeriodicalId":13009,"journal":{"name":"Hygiene and sanitation","volume":"302 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139152423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-28DOI: 10.47470/0016-9900-2023-102-12-1303-1308
E. Katamanova, D. V. Rusanova, Polina V. Kazakova
Introduction. Elimination of the consequences of emergency situations (ES) involves increased physical and psychological stress, as well as the direct aggressive impact of chemical and physical factors. Currently, the problem of environmental hazard is environmental pollution from the activities of «Usolyekhimprom», where on an area of 610 hectares there are tens of thousands of tons of harmful substances, including metallic mercury. On the territory of this enterprise, employees of the Federal Environmental Operator and the Ministry of Emergency Situations are currently engaged in eliminating environmental pollution. Over the past two years, a number of measures have been taken at the industrial site of «Usoliekhimprom» to dismantle buildings and demercurize. For 2023–2024 reconstruction, dismantling and disposal of the destroyed buildings of the enterprise are planned, in this regard, the liquidators may be affected by an even wider range of adverse factors. Employees of the East-Siberian Institute of Medical and Ecological Research conduct dynamic monitoring of the liquidators. The purpose of the study was to evaluate the neurophysiological and psychological indicators in liquidators in eliminating environmental pollution associated with the production of chemical products to prevent the occurrence of occupational pathology. Materials and methods. Forty males were examined. Electroneuromyographic examination (ENMG) was performed with testing of the sensory and motor components of the nerves of the upper extremities, electroencephalography (EEG), and psychological testing. Results. According to data of obtained ENMG parameters in the group of liquidators, a subthreshold decrease in the speed of impulse conduction in the area of the elbow joint was established during stimulation of the motor and sensory components of the ulnar nerve (up to 50 m/s). Analysis of interhemispheric coherence in the α-range in the group of liquidators revealed an increase in coherence in the right temporal leads (0.6 (0.4–0.7) G) compared with the standard values (0.35 (0.3–0.4) D) and weakening of coherent connections in the left frontal leads (0.35 (0.17–0.4) D). Changes in the mnestic sphere and the quality of life of the subjects were not revealed. Limitations. The limitation of the study was the lack of data on testing the motor and sensory components of the lower extremities during an electroneuromyographic examination and the lack of registration of evoked potentials during electroencephalography. Conclusion. The changes detected by ENMG indicate the manifestations of polyneuropathy at the preclinical stage. The analysis of interhemispheric coherence in the α-band revealed an increase in coherence in the right temporal leads and a weakening of coherent connections in the left frontal leads. The results of the medical and psychological study did not reveal any changes on the part of the mnestic sphere and the quality of life in the group of liquidators.
{"title":"Neurophysiological and psychological indicators of liquidators of chemical pollution of the environment","authors":"E. Katamanova, D. V. Rusanova, Polina V. Kazakova","doi":"10.47470/0016-9900-2023-102-12-1303-1308","DOIUrl":"https://doi.org/10.47470/0016-9900-2023-102-12-1303-1308","url":null,"abstract":"Introduction. Elimination of the consequences of emergency situations (ES) involves increased physical and psychological stress, as well as the direct aggressive impact of chemical and physical factors. Currently, the problem of environmental hazard is environmental pollution from the activities of «Usolyekhimprom», where on an area of 610 hectares there are tens of thousands of tons of harmful substances, including metallic mercury. On the territory of this enterprise, employees of the Federal Environmental Operator and the Ministry of Emergency Situations are currently engaged in eliminating environmental pollution. Over the past two years, a number of measures have been taken at the industrial site of «Usoliekhimprom» to dismantle buildings and demercurize. For 2023–2024 reconstruction, dismantling and disposal of the destroyed buildings of the enterprise are planned, in this regard, the liquidators may be affected by an even wider range of adverse factors. Employees of the East-Siberian Institute of Medical and Ecological Research conduct dynamic monitoring of the liquidators. The purpose of the study was to evaluate the neurophysiological and psychological indicators in liquidators in eliminating environmental pollution associated with the production of chemical products to prevent the occurrence of occupational pathology. Materials and methods. Forty males were examined. Electroneuromyographic examination (ENMG) was performed with testing of the sensory and motor components of the nerves of the upper extremities, electroencephalography (EEG), and psychological testing. Results. According to data of obtained ENMG parameters in the group of liquidators, a subthreshold decrease in the speed of impulse conduction in the area of the elbow joint was established during stimulation of the motor and sensory components of the ulnar nerve (up to 50 m/s). Analysis of interhemispheric coherence in the α-range in the group of liquidators revealed an increase in coherence in the right temporal leads (0.6 (0.4–0.7) G) compared with the standard values (0.35 (0.3–0.4) D) and weakening of coherent connections in the left frontal leads (0.35 (0.17–0.4) D). Changes in the mnestic sphere and the quality of life of the subjects were not revealed. Limitations. The limitation of the study was the lack of data on testing the motor and sensory components of the lower extremities during an electroneuromyographic examination and the lack of registration of evoked potentials during electroencephalography. Conclusion. The changes detected by ENMG indicate the manifestations of polyneuropathy at the preclinical stage. The analysis of interhemispheric coherence in the α-band revealed an increase in coherence in the right temporal leads and a weakening of coherent connections in the left frontal leads. The results of the medical and psychological study did not reveal any changes on the part of the mnestic sphere and the quality of life in the group of liquidators.","PeriodicalId":13009,"journal":{"name":"Hygiene and sanitation","volume":"53 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139152015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}