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Was It a Case of “Flatbush Diabetes” with Severe Hypertriglyceridemia? 这是一起“Flatbush糖尿病”合并严重高甘油三酯血症的病例吗?
IF 0.2 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-06-01 DOI: 10.1055/s-0042-1756686
Mouza Mohammed Al-Nuaimi, M. Ismail, A. Elhouni
We present a case of a morbidly obese 27 years male patient who was admitted with sudden onset abdominal pain and crashed into diabetic ketoacidosis as new-onset diabetes and discuss the possible etiology of this combined picture of acute pancreatitis and severe hypertriglyceridemia. Flatbush diabetes was, meanwhile, thought of due to his morbid obesity that in turn raised our suspicion of acute insulin-requiring type 2 diabetes mellitus versus T1 diabetes mellitus. Ketosis-prone diabetes or Flatbush diabetes is a syndrome in which diabetes commences with ketoacidosis in patients who are glutamic acid decarboxylase and antiislet cell antibody negative and have no known precipitating causes. They are usually middle-aged, overweight, or mildly obese, and in many reports, they are likely to be male with a family history of type 2 diabetes mellitus; they present with new-onset severe hyperglycemia and ketosis or frank diabetic ketoacidosis. After intensive initial insulin therapy, many patients become insulin-independent and can be well controlled on diet plus oral medications or, more rarely, diet alone.
我们报告了一个27岁的病态肥胖男性患者,他因突然腹痛而入院,并作为新发糖尿病而陷入糖尿病酮症酸中毒,并讨论了这种急性胰腺炎和严重高甘油三酯血症合并的可能病因。与此同时,Flatbush糖尿病被认为是由于他的病态肥胖,这反过来又引起了我们对急性需要胰岛素的2型糖尿病与T1型糖尿病的怀疑。酮症易感性糖尿病或Flatbush糖尿病是一种综合征,在谷氨酸脱羧酶和抗胰岛细胞抗体阴性且无已知沉淀原因的患者中,糖尿病以酮症酸中毒开始。他们通常是中年人,超重或轻度肥胖,在许多报告中,他们可能是男性,有2型糖尿病家族史;他们表现为新发的严重高血糖和酮症或糖尿病酮症酸中毒。经过最初的胰岛素强化治疗后,许多患者成为胰岛素独立型患者,可以很好地控制饮食加口服药物,或者更罕见的是单独饮食。
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引用次数: 0
Ramadan Fasting in Health and Disease in 2021: A Narrative Review 2021年斋月在健康和疾病方面的斋戒:述评
IF 0.2 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-06-01 DOI: 10.1055/s-0042-1757473
Reem Hassan-Beck, Khadija Hafidh, Amal Badi, K. Dougman, M. Karmo, R. Mir, S. Beshyah
Abstract Introduction:  The literature on the health aspects of Ramadan fasting (RF) is widely spread in many journals. Materials and Methods:  This is a narrative review of data obtained from the PubMed database (National Library of Medicine, Bethesda, Maryland, United States). We used the search term “Ramadan fasting,” and relevant records were examined. The publications are narrated thematically. Results:  The publications spanned fundamental, clinical, professional, cultural, and advocacy facets. The publications crossed conventional disciplinary lines and geographical locations and appeared in journals with different access systems. The contents are presented under the themes that emerged depending on the retrieved literature. This year basic coverage included changes in physiology and nutrition during Ramadan. However, the clinical issues included a wide range of topics. These included the impact of RF on nonalcoholic fatty liver disease and adjustments needed in endocrine replacement therapy for hypothyroidism and adrenal insufficiency. Coverage also included chronic kidney disease. The impact on maternal health, fetal well-being, and long-term effects of RF exposures were addressed in several studies. Studies in cardiovascular medicine focused on blood pressure and cardiovascular risk factors. Sports medicine and athletes' well-being received somewhat prominent coverage. The impact on renal function, particularly in patients with chronic kidney disease, was investigated by a few authors. Several groups addressed the eyes' structure and function, neurological conditions, especially headache disorders, and hematological and oncological conditions. Finally, the impact of RF on several aspects of mental health and well-being was addressed by various groups. Conclusions:  Health aspects of RF received a sustained academic interest with a broad spectrum in 2021. This narration provides an overview of the year's scholarly health-related literature on various aspects of health and disease. It should help researchers and clinicians catch up quickly with the health concerns during Ramadan.
摘要简介: 关于斋月禁食健康方面的文献在许多期刊上广泛传播。材料和方法: 这是从PubMed数据库(美国马里兰州贝塞斯达国家医学图书馆)获得的数据的叙述性综述。我们使用了搜索词“斋月禁食”,并检查了相关记录。出版物按主题叙述。结果: 这些出版物涵盖了基础、临床、专业、文化和宣传方面。这些出版物跨越了传统的学科界限和地理位置,出现在具有不同访问系统的期刊上。根据检索到的文献,在出现的主题下呈现内容。今年的基本覆盖范围包括斋月期间生理和营养的变化。然而,临床问题包括广泛的主题。其中包括RF对非酒精性脂肪肝的影响,以及甲状腺功能减退和肾上腺功能不全的内分泌替代治疗所需的调整。覆盖范围还包括慢性肾脏疾病。几项研究讨论了射频暴露对产妇健康、胎儿健康和长期影响的影响。心血管医学的研究重点是血压和心血管危险因素。运动医学和运动员的健康状况得到了一些突出的报道。一些作者研究了对肾功能的影响,特别是对慢性肾脏疾病患者的影响。几个小组讨论了眼睛的结构和功能、神经系统疾病,尤其是头痛疾病,以及血液学和肿瘤学疾病。最后,各个小组讨论了RF对心理健康和幸福感的几个方面的影响。结论: 2021年,射频的健康方面受到了广泛的学术关注。这篇叙述概述了今年关于健康和疾病各个方面的学术健康相关文献。它应该有助于研究人员和临床医生在斋月期间迅速了解健康问题。
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引用次数: 0
Erratum: Ramadan Fasting in Health and Disease in 2021: A Narrative Review 勘误:2021年斋月在健康和疾病方面的斋戒:叙述性回顾
IF 0.2 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-06-01 DOI: 10.1055/s-0042-1758814
Reem Hassan-Beck, Khadija Hafidh, Amal Badi, K. Dougman, M. Karmo, R. Mir, S. Beshyah
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引用次数: 0
Cancer Survivorship, Diabetes, and Pain Control 癌症生存率、糖尿病和疼痛控制
IF 0.2 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-06-01 DOI: 10.1055/s-0042-1756683
E. Elkhammas, S. Beshyah
1Division of Transplantation, Department of Surgery, The Ohio State University, Columbus, Ohio, United States 2Department of Medicine, Dubai Medical College for Girls, Dubai, United Arab Emirates 3Department of Endocrinology, Yas Clinic Khalifa City, Abu Dhabi, United Arab Emirates 4Department of Medicine, College of Medicine and Health Sciences, Khalifa University, Abu Dhabi, United Arab Emirates
1美国俄亥俄州哥伦布市俄亥俄州立大学外科移植科2迪拜女子医学院医学部3阿拉伯联合酋长国阿布扎比市哈利法市亚斯诊所内分泌科4阿布扎比哈利法大学医学与健康科学学院医学部,阿拉伯联合酋长国
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引用次数: 0
Neurological Complications Associated with Hemodialysis 与血液透析相关的神经系统并发症
IF 0.2 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-06-01 DOI: 10.1055/s-0042-1756685
J. Rissardo, A. Caprara
Dear Editor, We read the article entitled “Common Complications of Hemodialysis: A Clinical Review” on the esteemed “Ibnosina Journal of Medicine and Biomedical Sciences” with great interest. Habas et al reviewed the hemodialysis complications that frequently affect chronic kidney disease patients. They observed that cardiovascular system disorders and infections related to dialysis are the main causes of death in patients undergoing hemodialysis. Habas et al stated that renal transplantation should be offered to individuals at the early stages of end-stage renal disease to prevent the “legacy effects” of delayed treatment.1 Herein, we would like to discuss recent articles published about neurological complications associated with hemodialysis. Themost commonneurologicalmanifestations that can be caused or worsened by dialysis are cognitive decline, central pontine myelinolysis, headache, neuropathy, stroke, myopathy, sleep disorders, restless legs syndrome, Wernicke’s encephalopathy, and autonomic dysfunction (►Fig. 1).1–5 Cephalgia occurs in more than 70% of dialytic individuals. So, it can significantly affect the quality of life of patients with end-stage renal disease. Aoun et al assessed the incidence of headache and hypotension between patients drinking regular or decaffeinated coffee during dialysis. A total of 139 patients completed the trial, in which headache was diagnosed in 35% of patients. Apparently, caffeine intake did not prevent headache episode occurrence in these individuals. It is noteworthy that in a subgroup analysis, headaches tended to be more frequent in nonhypertensive patients with the highest potassium dialysate.2 Cheng et al systematically reviewed the literature of qualitative studies that report patient experience and perspectives on sleep in dialysis. They found that the most critical point related to sleep disruption is the unrelenting demands of treatment and the high symptom burden of renal failure. So, sleep problems are probably not directly associated with dialysis. Instead, they are related to the psychological stress surrounding this procedure. However, those with severe sleep symptoms should be referred to sleep specialists to review for further investigation and management.3 “Is cognition removed during dialysis?” It is a relevant question that has increased the discussion about dialysisinduced dementia in the last decades. In themiddle of 1970s, it was observed that aluminum phosphate contamination was associated with cognitive decline so water purification techniques were developed. Cognitive impairment is independently associated with kidney disease and increases in prevalence with declining kidney function. Crowe et al revealed that this clinical feature is related to advanced vascular aging, mood disorders, sleep dysregulation, and the effect of dialysis itself. Therefore, it is believed that the recurrent intradialytic decline in cerebral blood flow could predispose to cerebral ischemic injuries le
尊敬的编辑,我们怀着极大的兴趣阅读了《Ibnosina Journal of Medicine and Biomedical Sciences》上题为“血液透析的常见并发症:A Clinical Review”的文章。Habas等人回顾了经常影响慢性肾脏疾病患者的血液透析并发症。他们观察到,与透析相关的心血管系统疾病和感染是血液透析患者死亡的主要原因。Habas等人指出,应在终末期肾病的早期阶段提供肾移植,以防止延迟治疗的“遗留效应”在此,我们想讨论最近发表的关于血液透析相关神经系统并发症的文章。可由透析引起或加重的最常见神经系统表现为认知能力下降、脑桥中央髓鞘溶解、头痛、神经病变、中风、肌病、睡眠障碍、不宁腿综合征、韦尼克脑病和自主神经功能障碍。1) 1 - 5头痛症发生在超过70%的透析患者中。因此,它可以显著影响终末期肾脏疾病患者的生活质量。Aoun等人评估了透析期间饮用普通咖啡或不含咖啡因咖啡的患者之间头痛和低血压的发生率。共有139名患者完成了试验,其中35%的患者被诊断为头痛。显然,咖啡因的摄入并不能预防这些人的头痛发作。值得注意的是,在亚组分析中,头痛在透析钾最高的非高血压患者中更常见Cheng等人系统地回顾了定性研究的文献,这些文献报道了透析患者的经验和对睡眠的看法。他们发现,与睡眠中断有关的最关键的一点是持续不断的治疗要求和肾衰竭的高症状负担。因此,睡眠问题可能与透析没有直接关系。相反,它们与手术过程中的心理压力有关。然而,那些有严重睡眠症状的人应该转到睡眠专家那里进行进一步的调查和治疗“在透析过程中认知会消失吗?”这是一个相关的问题,在过去的几十年里,透析性痴呆的讨论越来越多。在20世纪70年代中期,人们观察到磷酸铝污染与认知能力下降有关,因此开发了水净化技术。认知障碍与肾脏疾病独立相关,并随着肾功能下降而增加。Crowe等人发现这一临床特征与血管晚期老化、情绪障碍、睡眠失调以及透析本身的影响有关。因此,我们认为复发性脑血流量下降可能导致脑缺血损伤,从而导致血管性痴呆Donaldson等报道了3例透析相关的非动脉性缺血性视神经病变,并复习了相关文献。这种灾难性的后果可能继发于分析性低血压。大多数受影响的个体为中年男性,双侧受累约占60%。值得一提的是,预防血栓性低血压及其急性处理仍然是避免并发症发生的最重要建议
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引用次数: 0
Ibnosina journal of medicine and biomedical sciences 2018 and beyond 伊布诺西那医学与生物医学杂志2018及以后
IF 0.2 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2022-03-01 DOI: 10.4103/IJMBS.IJMBS_84_17
E. Elkhammas, S. Beshyah
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引用次数: 0
Pharmacy practice in COVID-19 from a Middle Eastern and African perspective: A narrative review 中东和非洲视角下的2019冠状病毒病药房实践述评
IF 0.2 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-10-01 DOI: 10.4103/ijmbs.ijmbs_58_21
Haider Al-Saffar, Rasha Aljazzar, Amina Al-Saffar
The coronavirus disease 2019 (COVID-19) had a worldwide impact on all aspects of life and primarily on clinical practice involving all health-care professionals. Pharmacists are at the forefront of all clinical facilities in hospitals and the community. We aimed to provide a narrative overview of the global literature on the impact of COVID-19 changing roles and pharmacists' contribution to the overall clinical care during the COVID-19 pandemic. We conducted a narrative, nonsystematic review of the international literature from a single major medical online database, PubMed, between February 1, 2020, and June 30, 2021. The relevant articles were narrated in a concise thematic account. During the COVID-19 pandemic, pharmacists had to serve their responsibilities alongside other activities while the entire world was fighting an invisible virus. However, it was much more complicated than before because the novel coronavirus is intractable. There was no vaccine or established therapeutic guidelines when it manifested suddenly. As part of an interdisciplinary team, community pharmacists may carry out their responsibilities and play an essential role in disease control and management. However, they may need to be appropriately prepared, trained, and equipped to deal with pandemic and postpandemic situations.
2019年冠状病毒病(COVID-19)对全球生活的各个方面产生了影响,主要影响到所有卫生保健专业人员的临床实践。药剂师在医院和社区的所有临床设施中处于最前沿。我们的目的是对全球关于COVID-19角色变化的影响以及药剂师在COVID-19大流行期间对整体临床护理的贡献的文献进行概述。我们对2020年2月1日至2021年6月30日期间来自单一主要医学在线数据库PubMed的国际文献进行了叙述性非系统综述。有关的文章以简明扼要的专题叙述。在新冠肺炎大流行期间,全世界都在与一种看不见的病毒作斗争,药剂师不得不与其他活动一起履行职责。然而,由于新型冠状病毒难以治疗,情况比以前复杂得多。当它突然出现时,没有疫苗或既定的治疗指南。作为一个跨学科团队的一部分,社区药剂师可以履行他们的职责,在疾病控制和管理中发挥重要作用。然而,他们可能需要得到适当的准备、培训和装备,以应对大流行和大流行后的情况。
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引用次数: 1
The prevalence of short stature among school children and adolescents in Tripoli, Libya in 2009-2010 2009-2010年,利比亚的黎波里学童和青少年身材矮小的普遍程度
IF 0.2 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-10-01 DOI: 10.4103/ijmbs.ijmbs_61_21
Mabruka Ramadan, Rowida M Khashebi, F. Rajab
Background: Short stature has an impact on children's physical and mental health. Data on the prevalence of short stature in Libyan children are limited. Objectives: We aimed to ascertain the prevalence of short stature among school children in Tripoli, Libya. Patients and Methods: In this cross-sectional study, we included 419 school children (235 boys and184 girls) selected from different primary and preparatory schools in the City of Tripoli. The study was conducted between April 2009 and October 2010. Trained pediatricians took their anthropometric measurements (i.e., height and weight). The WHO-2007 Z-score charts and UK-WHO growth charts were used to calculate the prevalence of short stature (defined as standard deviation score of height <2 in same gender and age). Results: The overall prevalence of short stature using WHO-2007 Z-score and UK-WHO growth charts were 5.0% and 5.7%, respectively. (4.3% was moderate and 0.7% was severe). Boys and girls had no significant difference in the prevalence of short stature using 2007 WHO reference data (5.5% vs. 4.3%; P = 0.656). Similarly, there was no difference between the prevalence of short stature between boys and girls when applying UK-WHO growth charts (6.8% vs. 4.3%; P = 0.3). There is a statistically significant relationship between the prevalence of short stature (increase) and students' increasing age. Conclusions: Short stature is not an uncommon problem in children; they need early assessment because intervention time is crucial in this condition.
背景:身材矮小会影响儿童的身心健康。关于利比亚儿童身材矮小患病率的数据有限。目标:我们旨在确定利比亚的黎波里学童中身材矮小的普遍性。患者和方法:在这项横断面研究中,我们纳入了419名学童(235名男孩和184名女孩),他们来自的黎波里市不同的小学和预备学校。该研究于2009年4月至2010年10月期间进行。经过培训的儿科医生进行了人体测量(即身高和体重)。使用WHO-2007 Z评分图和UK-WHO生长图来计算身材矮小的患病率(定义为在相同性别和年龄中身高<2的标准差分数)。结果:使用WHO-2007 Z评分和UK-WHO增长图,身材矮小的总体患病率分别为5.0%和5.7%。(4.3%为中度,0.7%为重度)。使用2007年世界卫生组织参考数据,男孩和女孩身材矮小的患病率没有显著差异(5.5%对4.3%;P=0.656),应用UK-WHO增长图时,男孩和女孩的身材矮小患病率之间没有差异(6.8%对4.3%;P=0.3)。身材矮小(增长)的患病率与学生年龄的增长之间存在统计学显著关系。结论:身材矮小在儿童中并不罕见;他们需要早期评估,因为在这种情况下,干预时间至关重要。
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引用次数: 0
Motives for participation in physical activity among libyan adults 利比亚成年人参加体育活动的动机
IF 0.2 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-10-01 DOI: 10.4103/ijmbs.ijmbs_39_21
S. Elmahgoub, Hassan Mohamed, A. Hmmier, A. Eltaguri
Objectives: The study aimed to determine motives for physical activity (PA) participation in Libyan adults and compare motives related to sex and places of participation (indoor vs. outdoor). Participants and Methods: A cross-sectional questionnaire-based study was conducted. The questionnaire was adapted from the Exercise Motivation Inventory version 2. Six hundred Libyan adults (300 males and 300 females) were involved in this study. Results: In general, positive health, activation, and avoiding ill-health (4.83 ± 0.89, 4.20 ± 0.93, 4.09 ± 1.00, mean ± standard deviation [SD]) were the most common motives for PA participation, respectively, while competition, affiliation, health pressure, and social status (2.73 ± 1.29, 2.69 ± 1.21, 2.59 ± 1.29, 2.50 ± 1.24, mean ± SD) were the least motivational factors, respectively. In males, enjoyment, social status, affiliation, competition, health pressure, strength, and endurance were significantly higher (P= 0.017, 0.000, 0.010, 0.000, 0.007, 0.024). In contrast, activation, positive health, weight control, appearance, and fitness were significantly higher in females (P= 0.002, 0.001, 0.000, 0.000, 0.005). In addition, health pressure, avoiding ill-health, and positive health motives were similar in adults practicing PA indoor and outdoor. In contrast, other motives tended to be significantly higher in indoor activities. Conclusions: Motives for PA participation differ across participants' sex and places of participation among Libyan adults. It is crucial to understand the motives for PA participation to capitalize on the positive motives to increase their participation and enhance the positive effects of increased PA in the community.
目的:该研究旨在确定利比亚成年人参与体育活动的动机,并比较与性别和参与场所(室内和室外)相关的动机。参与者和方法:进行了一项基于横断面问卷的研究。该问卷改编自运动动机调查表第2版。600名利比亚成年人(300名男性和300名女性)参与了这项研究。结果:总体而言,积极的健康、积极的活动和避免健康不良(4.83±0.89、4.20±0.93、4.09±1.00,平均值±标准差[SD])分别是参与PA的最常见动机,而竞争、从属关系、健康压力和社会地位(2.73±1.29、2.69±1.21、2.59±1.29和2.50±1.24,均数±SD)是最少的动机因素,分别地在男性中,快乐、社会地位、从属关系、竞争、健康压力、力量和耐力显著更高(P=0.017、0.000、0.010、0.000和0.007、0.024)。相比之下,女性的活跃度、积极健康、体重控制、外表和健身显著更高,在室内和室外进行PA的成年人中,积极的健康动机是相似的。相比之下,在室内活动中,其他动机往往明显更高。结论:利比亚成年人参与PA的动机因参与者的性别和参与地点而异。了解PA参与的动机至关重要,以利用积极的动机来增加他们的参与,并增强增加PA在社区中的积极影响。
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引用次数: 0
One-year analysis of trends of COVID-19 in Libya: Cases, deaths, and laboratory testing 利比亚新冠肺炎趋势一年分析:病例、死亡和实验室检测
IF 0.2 Q3 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-10-01 DOI: 10.4103/ijmbs.ijmbs_73_21
R. Elmehdawi, Sara Glessa, Amal Elfakhri, A. Elhaddad, Ahmed Elhassi
Introduction: The coronavirus disease 2019 (COVID-19) epidemic in Libya started at the end of March 2020. Since then, the number of daily reported cases has progressively increased. Objectives: This study aims to analyze the trends and dynamics of the epidemic in Libya. Materials and Methods: The study analyzed the data reported daily by the Libyan national center of disease control. Results: The total number of tests performed per thousand people was 121.08 test/1000 people, which is a modest rate compared with countries categorized in the same income group. The overall positivity rate of all performed tests over 1 year was 18.1%. During most of the weeks, the positivity rate was far higher than the 5% rate indicating that the epidemic was out of control most of the year. The level of community transmission was moderate to substantial during most of the year, reflecting the weakness in applying the public health control measures. The calculated 1-year instant case-fatality rate of COVID-19 in Libya was 1.89%, comparable to that in other upper-middle-income countries. Conclusions: The number of performed tests in Libya during the 1st year of the COVID-19 epidemic is inadequate and must be at least doubled to increase the chances of diagnosing more potential cases. Based on the current positivity rate, the epidemic appears to be out of control since July 2021. This should urge the authorities to impose further enforcement of the standard public health measures.
简介:2019冠状病毒病(新冠肺炎)在利比亚的流行始于2020年3月底。自那时以来,每日报告的病例数量逐渐增加。目的:本研究旨在分析利比亚疫情的趋势和动态。材料和方法:该研究分析了利比亚国家疾病控制中心每天报告的数据。结果:每千人进行的检测总数为每千人121.08次,与同一收入组的国家相比,这是一个适中的比率。一年内所有检测的总体阳性率为18.1%。在大多数周内,阳性率远高于5%,这表明疫情在一年中的大部分时间都处于失控状态。在一年的大部分时间里,社区传播水平为中度至重度,反映出公共卫生控制措施的实施不力。经计算,利比亚新冠肺炎的1年即时病死率为1.89%,与其他中高收入国家相当。结论:新冠肺炎疫情第一年期间,利比亚进行的检测数量不足,必须至少增加一倍,以增加诊断更多潜在病例的机会。根据目前的阳性率,自2021年7月以来,疫情似乎已经失控。这应敦促当局进一步执行标准公共卫生措施。
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引用次数: 0
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Ibnosina Journal of Medicine and Biomedical Sciences
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