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Sandwich Nanolayers Deposited on Curvedly Double-Polished Optical Fiber for Surface Plasmon Resonance Sensor of Simultaneous Dual-Parameter Detection 弯曲双抛光光纤夹层纳米层用于表面等离子体共振传感器双参数同步检测
IF 2.4 4区 工程技术 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2026-02-03 DOI: 10.1109/JPHOT.2026.3660069
Mengmeng Wang;Yongru Li;Siying Li;Mingyue Li;Xian Li;Xing Guo;Zewei Luo;Yixiang Duan
Cross-sensitivity reduces the reliability of ambient temperature (T) and refractive index (RI) detection during the process of photothermal therapy (PTT). Current dual-parameter sensors focus on RI and T measurement in spatially separated regions, limiting the advancement of PTT. To tackle this issue, we proposed a curvedly double-polished optical fiber surface plasmon resonance (SPR) sensor based on sandwich nanolayers of gold film–gold nanoparticle (AuNPs)–polydimethylsiloxane (PDMS), which successfully achieved simultaneous dual-parameter detection of refractive index (RI) and temperature (T) within a single spatial region. Fiber bending and polishing techniques deepen the effective penetration distance of the evanescent field, strengthening the coupling between light and electrons in metal layer. The sandwich nanolayers modulate the SPR location in response to the fluctuations of ambient RI and T. Simultaneous detection was achieved by monitoring dual SPR signals. Two typical curvedly double-polished structures, namely side-polished and front-polished, exhibited similar sensitivity but distinctive confinement loss. Key factors including polishing depth, bending radius, Au film, and PDMS thickness for sensing performance were explored. Under optimal conditions, the proposed side-polished and front-polished fiber SPR sensor achieved sensitivities of 1502 nm/RIU and 1.86 nm/°C, 1382 nm/RIU and 1.88 nm/°C, respectively. With a simple structure and high integrability, it provides a viable solution for in vivo cyto-sensing and therapeutic applications.
交叉灵敏度降低了光热治疗(PTT)过程中环境温度(T)和折射率(RI)检测的可靠性。目前的双参数传感器主要集中在空间分离区域的RI和T测量,限制了PTT的发展。为了解决这一问题,我们提出了一种基于金膜-金纳米颗粒(AuNPs) -聚二甲基硅氧烷(PDMS)夹层的弯曲双抛光光纤表面等离子体共振(SPR)传感器,该传感器成功地实现了在单个空间区域内同时检测折射率(RI)和温度(T)的双参数检测。光纤弯曲和抛光技术加深了倏逝场的有效穿透距离,加强了金属层中光与电子之间的耦合。夹层纳米层根据环境中RI和t的波动调节SPR的位置,通过监测双SPR信号实现同步检测。两种典型的弯曲双抛光结构,即侧面抛光和正面抛光,具有相似的灵敏度,但约束损失不同。探讨了影响传感性能的关键因素包括抛光深度、弯曲半径、Au膜和PDMS厚度。在最优条件下,侧面抛光和正面抛光的光纤SPR传感器的灵敏度分别为1502 nm/RIU和1.86 nm/°C, 1382 nm/RIU和1.88 nm/°C。它结构简单,可集成性高,为体内细胞传感和治疗应用提供了可行的解决方案。
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引用次数: 0
The Improved Quasi-Fermi-Level Separation of InGaAs Well-Cluster Composite Nanostructure for Ultra-Wide Tunable Lasers 用于超宽可调谐激光器的InGaAs井簇复合纳米结构的改进准费米能级分离
IF 2.4 4区 工程技术 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2026-01-30 DOI: 10.1109/JPHOT.2026.3659485
Ru Wang;Zeng Jin;Yihan Zhang;Xinyang Qi;Zixuan Chen;Yujia Liu;Kehan Li;Qingnan Yu;Wei Wang;Sungang Huang
The development and application of tunable lasers have been constrained by a limited tuning range, primarily due to the small quasi-Fermi-level separation (ΔEf) and low carrier band-filling levels. This study demonstrates an InGaAs/GaAs well-cluster composite (WCC) nanostructure, developed based on the indium-rich cluster effect. The ΔEf and gain curves were obtained and analyzed by collecting photoluminescence (PL) spectra emitted from two 500-µm-long multisection regions under varying carrier concentrations (9.0 × 1017–9.6 × 1017 cm−3) and working temperatures (280–330 K). Compared to traditional InGaAs/GaAs quantum well structures under identical working conditions, the ΔEf and gain bandwidth of the WCC structure were observed to be 1.08 and 5.3 times higher. This enhancement is attributed to the formation mechanism of the WCC structure, which contributes to a broader ΔEf and expanded spectral characteristics. This configuration highlights the significant application potential of the WCC nanostructure in advancing tunable laser technology.
可调谐激光器的发展和应用一直受到有限的调谐范围的限制,主要是由于准费米能级的小分离(ΔEf)和低载流子带填充能级。本研究展示了一种基于富铟簇效应的InGaAs/GaAs井簇复合材料(WCC)纳米结构。在不同载流子浓度(9.0 × 1017 ~ 9.6 × 1017 cm−3)和工作温度(280 ~ 330 K)下,收集两个500µm长多截面区域的光致发光(PL)光谱,得到ΔEf和增益曲线并进行分析。在相同的工作条件下,与传统的InGaAs/GaAs量子阱结构相比,WCC结构的ΔEf和增益带宽分别提高了1.08倍和5.3倍。这种增强归因于WCC结构的形成机制,它有助于更广泛的ΔEf和扩展的光谱特征。这种结构突出了WCC纳米结构在推进可调谐激光技术方面的重要应用潜力。
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引用次数: 0
Statistical Distributions and Correlations of Modal Dispersion in All Mode-Coupling Regimes 所有模态耦合状态下模态色散的统计分布和相关性
IF 2.4 4区 工程技术 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2026-01-28 DOI: 10.1109/JPHOT.2026.3658708
Fengtao Sun;Xinran Zhu;Xiaoxiao Liu;Minghua Cao;Hefu Li;Xia Zhang;Zhenshan Yang
While most prior studies on the statistical properties of modal dispersion (MD) in multiple-mode fibers have been primarily focused on the strong mode-coupling regime, in this paper we investigate the statistics of 1st- and 2nd-order MD across the full range of weak-, intermediate- and strong-coupling regimes. By simulating and analyzing a randomly-perturbed 6-mode fiber, we show that, under proper normalization of the MD quantities, the probability density functions (PDFs) would change significantly with the fiber length $L$ in the weak coupling regime, while eventually get steady – i.e., no longer change as $L$ further increases – in the strong coupling regime, and the random mode-coupling affects the 2nd-order MD on a considerably larger fiber length scale than that for the 1st-order MD. Furthermore, by calculating the joint bi-variate PDFs, the correlations among the 1st- and 2nd-order MD quantities are analyzed, which reveals that the correlation between the group-delay difference and the frequency variation of the principal modes is much stronger than the correlation between the group-delay difference and its frequency derivative.
以往对多模光纤中模态色散(MD)统计特性的研究主要集中在强模耦合区域,而本文研究了一阶和二阶模态色散在弱、中、强耦合区域的统计特性。通过对随机摄动6模光纤的模拟和分析,我们发现,在对MD量进行适当的归一化处理后,在弱耦合状态下,概率密度函数(pdf)会随着光纤长度$L$发生显著变化,而在强耦合状态下,概率密度函数最终趋于稳定,即随着$L$的进一步增加不再发生变化。随机模耦合在更大的光纤长度尺度上对二阶模量的影响明显大于对一阶模量的影响。此外,通过计算联合双变量PDFs,分析了一阶和二阶模量之间的相关性,发现群延迟差与主模频率变化的相关性远大于群延迟差与其频率导数的相关性。
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引用次数: 0
Non-Invasive Label-Free Optical Biosensor for Accurate Peptide Detection Using Refractive Index Measurement and Machine Learning 利用折射率测量和机器学习进行精确肽检测的无创无标签光学生物传感器
IF 2.4 4区 工程技术 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2026-01-28 DOI: 10.1109/JPHOT.2026.3657765
Trupti Kamani;Shobhit K. Patel;Abdullah Baz;Om Prakash Kumar
Peptide diagnostics serve an important role for initial disease recognition, pharmaceutical evaluation, and environmental monitoring. Conventional methods for diagnosis typically involve labelling concepts that reduce sensitivity, increase test complexities, and limitations in real-time analysis. In the proposed work, we have introduced Corner-Triangle, Floral Geometry Refractive Index Biosensor (CTFGRIB) for monitoring peptide concentrations by names, Glycylleucine (Gly-Leu), Triglycine (Tri), Glycine (Gly), Glycytyrosine (Gly-Tyr), Diglycine (Dig), and Glycylaspartate (Gly-Asp) with a combination of machine learning evaluation. A periodical arrangement of corner-triangle patterns surrounded by a floral layout, as a distinctive geometry, provides a number of synergistic benefits that directly boost biosensing capabilities. The parametric assessments involve outstanding performance parameters with the favourable values of sensitivity being 1023.25 nm/RIU, and favourable values of detection limit are 0.0733 RIU for the Gly-Leu peptide cell. The favourable quality factor value of 24.0368, and the figure of merit value of 10.9508 RIU-1 have been achieved for the Gly-Leu peptide cell. The favourable transmittance rate of 33.6%, 33.3%, 33.0%, 33.0%, 32.9%, and 32.9% have been observed for Gly-Leu, Tri, Gly, Gly-Tyr, Dig, and Gly-Asp, respectively. The optimised R-squared value of 0.997604 and the MSE value of 9.607930 × 10-05 have been achieved from the machine learning method.
多肽诊断在疾病初始识别、药物评价和环境监测中发挥着重要作用。传统的诊断方法通常涉及标签概念,降低了灵敏度,增加了测试的复杂性,并限制了实时分析。在提议的工作中,我们引入了角三角形,花卉几何折射率生物传感器(CTFGRIB),用于通过名称监测肽浓度,甘氨酸(Gly- leu),甘氨酸(Tri),甘氨酸(Gly),甘氨酸(Gly),甘氨酸(Gly- tyr),二甘氨酸(Dig)和甘氨酸(Gly- asp)结合机器学习评估。由花卉布局包围的角三角形图案的周期性排列,作为一种独特的几何形状,提供了许多协同效益,直接提高了生物传感能力。参数评价包括突出的性能参数,灵敏度的有利值为1023.25 nm/RIU,检测限的有利值为0.0733 RIU。Gly-Leu肽细胞的有利品质因子值为24.0368,优值为10.9508 RIU-1。Gly- leu、Tri、Gly、Gly- tyr、Dig和Gly- asp的有利透过率分别为33.6%、33.3%、33.0%、33.0%、32.9%和32.9%。通过机器学习方法得到了优化后的r平方值0.997604和MSE值9.607930 × 10-05。
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引用次数: 0
Photonic Nanojet-Enabled Mode Matching for Ultralow-Loss Hybrid Fiber Interconnects 超低损耗混合光纤互连的光子纳米射流模式匹配
IF 2.4 4区 工程技术 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2026-01-28 DOI: 10.1109/JPHOT.2026.3658357
Muhammad Hanif Ahmed Khan Khushik;Shahzadi Bano;Guanliang Yu;Mian Muhammad Kamal;Jamal N.A. Hassan;Tianjun Ma
Coupling light into high-index-core hybrid optical fibers (HOFs) typically results in losses >2 dB. We exploit a photonic nanojet-like effect in a tapered subwavelength core to force fundamental mode expansion into the cladding, effectively solving the mismatch problem. For a 0.30 μm core, this strategy achieves a remarkable coupling loss of 0.31–0.32 dB and reduces Fresnel reflections to negligible levels (<0.1%) by ensuring near-perfect effective index matching with standard fiber. This powerful approach provides a generalized and practical framework for integrating diverse HOF platforms into conventional photonic infrastructure.
将光耦合到高折射率芯混合光纤(HOFs)中通常会导致损耗bbb20 dB。我们在锥形亚波长核心中利用光子纳米射流效应迫使基模扩展到包层中,有效地解决了失配问题。对于0.30 μm芯,该策略实现了0.31-0.32 dB的显著耦合损耗,并通过确保与标准光纤近乎完美的有效折射率匹配,将菲涅耳反射降低到可忽略不计的水平(<0.1%)。这种强大的方法为将各种HOF平台集成到传统光子基础设施中提供了一个通用的实用框架。
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引用次数: 0
Size-Change Behavior of Free-Form Microstructures During Ultrafast Laser Direct Writing Within Pure-Protein Precursors 纯蛋白前驱体内超快激光直写过程中自由形态微结构的尺寸变化行为
IF 2.4 4区 工程技术 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2026-01-26 DOI: 10.1109/JPHOT.2026.3658073
Daniela Serien;Aiko Narazaki
Ultrafast laser direct writing (LDW) is a versatile 3D microfabrication technology with a high spatial resolution, reduced heat accumulation, and a diverse range of applications usually tied to the applied precursor material. When using a protein precursor, it is possible to fabricate proteinaceous microstructures with the native protein function retained for use in cell cultures, lab-on-a-chip, and soft robotics. It is common to fabricate such proteinaceous microstructures by adhering them to glass. However, when we perform so-called free-form fabrication, without any substrate adhesion, we observe size changes during the fabrication process. This study quantified the in-precursor size changes to increase predictability. We also evaluated a potential mechanism for these changes by examining the role of protein hydration shells. These findings are expected to contribute to the fabrication of desired designs and promote the use of this technology.
超快激光直接写入(LDW)是一种多功能的3D微加工技术,具有高空间分辨率,减少热量积累,以及通常与应用前驱体材料相关的各种应用范围。当使用蛋白质前体时,可以制造具有保留天然蛋白质功能的蛋白质微结构,用于细胞培养,芯片实验室和软机器人。通过将这种蛋白质微观结构粘附在玻璃上来制造它们是很常见的。然而,当我们进行所谓的自由形式制造时,没有任何衬底粘附,我们观察到在制造过程中尺寸的变化。本研究量化了前体大小的变化,以增加可预测性。我们还通过检查蛋白质水合壳的作用来评估这些变化的潜在机制。预计这些发现将有助于制造所需的设计并促进该技术的使用。
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引用次数: 0
A Security-Enhanced NOMA Scheme Based on Dynamically Concealed Key- Accompanying Transmission 一种基于动态隐藏密钥伴随传输的安全增强NOMA方案
IF 2.4 4区 工程技术 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2026-01-22 DOI: 10.1109/JPHOT.2026.3656488
Ziming Liu;Lilong Zhao;Xiang Yao;Yaya Mao;Xiumin Song;Tingting Sun
This paper proposes a security-enhanced NOMA scheme based on dynamically concealed key-accompanying transmission. To improve security, in this paper, the 3D-LHemon model is utilized to encrypt the bit stream, symbols and subcarriers of high-power quadrature phase shift keying (QPSK) signals. The key is placed in a low-power binary phase shift keying (BPSK) signal, which is transmitted in parallel and superimposed with the high-power QPSK signal. Meanwhile, the phase points of the constellation diagram of the low-power signal are subjected to chaotic perturbation through Sinusoidal mapping. At the receiver, successive interference cancellation (SIC) decodes the high-power and low-power signals sequentially. Experimental results demonstrate the transmission of a 56 Gb/s orthogonal frequency division multiplexing (OFDM) signal over a 2-km 7-core optical fiber. Furthermore, the proposed scheme achieves an expansive key space of up to 10^87, effectively ensuring robust physical layer security. In contrast to existing chaos-based physical layer encryption for Non-Orthogonal Multiple Access (NOMA), this method applies chaotic encryption to high-power and low-power signals independently. This dual-layer approach significantly enhances system security without increasing computational overhead. Consequently, this scheme is capable of supporting a larger user base and holds promising potential for application in future optical networks.
提出了一种基于动态隐藏密钥伴随传输的安全增强的NOMA方案。为了提高安全性,本文采用3D-LHemon模型对大功率正交相移键控(QPSK)信号的比特流、符号和子载波进行加密。密钥被置于低功率二进制相移键控(BPSK)信号中,该信号与大功率QPSK信号并行叠加传输。同时,通过正弦映射对低功率信号星座图的相位点进行混沌摄动。在接收端,连续干扰消除(SIC)对高功率和低功率信号进行顺序解码。实验结果表明,在2 km的7芯光纤上传输56 Gb/s的正交频分复用(OFDM)信号。此外,该方案实现了高达10^87的扩展密钥空间,有效地保证了健壮的物理层安全性。与现有的基于混沌的非正交多址(NOMA)物理层加密相比,该方法分别对高功率和低功率信号进行混沌加密。这种双层方法在不增加计算开销的情况下显著提高了系统安全性。因此,该方案能够支持更大的用户群,并在未来的光网络中具有很大的应用潜力。
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引用次数: 0
Numerical Analysis of Localized Electric Field Enhancement in Apertureless Near Field Optical Microscopy 无孔径近场光学显微镜局部电场增强的数值分析
IF 2.4 4区 工程技术 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2026-01-21 DOI: 10.1109/JPHOT.2026.3656404
Ayushman Ramola;Amit Kumar Shakya;Yarden Mazor;Nezah Balal;Arik Bergman
In this work, we investigate the effects of two distinct physical mechanisms, the antenna effect and plasmon resonance, on electric field enhancement in representative geometrical structures and at the apex of a sharp tip. The three-dimensional (3D) apertureless surface near-field optical microscopy (a-SNOM) configuration is numerically investigated using a finite element method (FEM). Our results show good agreement with analytical predictions and prior numerical benchmarks. Accounting for both antenna effects and plasmon resonances is crucial for accurate modeling of local field amplification in nanostructured probes. Through a systematic parametric numerical study, we show that field enhancement is strongly influenced by illumination conditions, polarization angle, and tip geometry. Finally, these results clarify how intrinsic material properties, extrinsic geometric features, and optical excitation govern field enhancement in nanostructures.
在这项工作中,我们研究了两种不同的物理机制,天线效应和等离子体共振,对代表性几何结构和尖端尖端的电场增强的影响。采用有限元法对三维(3D)无孔表面近场光学显微镜(a- snom)结构进行了数值研究。我们的结果与分析预测和先前的数值基准很好地吻合。考虑天线效应和等离子体共振对于纳米结构探针中局部场放大的精确建模至关重要。通过系统的参数数值研究,我们发现光场增强受光照条件、偏振角和尖端几何形状的强烈影响。最后,这些结果阐明了材料的内在特性、外在几何特征和光激发如何影响纳米结构中的场增强。
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引用次数: 0
Design and Experimental Validation of a Line-Laser Autofocusing System With Extended Working Range 扩展工作范围线激光自动聚焦系统的设计与实验验证
IF 2.4 4区 工程技术 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2026-01-21 DOI: 10.1109/JPHOT.2026.3656585
Xiaoxiao Wei;Jintao Chen;Miao Fan;Hao Zhang;Yunfeng Nie
Autofocus (AF) technology plays a critical role in applications such as microscopic measurement, 3D visual scanning, and semiconductor defect inspection. Conventional photoelectric sensor-based AF systems in microscopy face challenges in simultaneously achieving high precision and a large operational range, primarily due to distortions introduced by objective lenses. To address this limitation, this paper presents a conjugate line-laser-based autofocus method. The proposed approach employs a semicircular light-blocking diaphragm to generate a line-semi-ellipse laser spot on the sample surface. Combined with a laser spot image feature extraction algorithm and mathematical modeling, the system achieves an autofocus range of 500 μm with a positioning accuracy within ±1/5 of the depth of field (DOF) when using a 20× objective lens. The developed AF system offers a simple, robust, and efficient solution for high-speed, high-precision microscopic autofocusing, enabling extended range without compromising accuracy.
自动对焦(AF)技术在显微测量、三维视觉扫描和半导体缺陷检测等应用中起着至关重要的作用。传统的基于光电传感器的自动对焦系统在显微镜中面临着同时实现高精度和大操作范围的挑战,主要是由于物镜引入的畸变。为了解决这一问题,本文提出了一种基于共轭线激光的自动对焦方法。该方法采用半圆形挡光膜在样品表面产生直线半椭圆激光光斑。结合激光光斑图像特征提取算法和数学建模,该系统在使用20倍物镜时实现了500 μm的自动对焦范围,定位精度在景深(DOF)的±1/5以内。开发的自动对焦系统为高速、高精度显微自动对焦提供了简单、强大和高效的解决方案,在不影响精度的情况下实现了更大的范围。
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引用次数: 0
Real-Time Brillouin Microscopy for Linewidth Imaging of Protein Condensates in Living Cells 实时布里渊显微镜用于活细胞中蛋白质凝聚物的线宽成像
IF 2.4 4区 工程技术 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2026-01-20 DOI: 10.1109/JPHOT.2026.3655716
C. Bartoli;N. D’Abbondanza;F. Gala;C. Marzaro;E. Pontecorvo;G. Ruocco;G. Zanini;L. Zhang;M. G. Garone;V. de Turris;A. Giuliani;G. di Timoteo;I. Bozzoni;A. Rosa;C. Testi
We propose a label-free, high-resolution approach to investigate pathological protein aggregation and aberrant phase behavior in living cells. Intracellular protein aggregates associated with neurodegenerative diseases are increasingly recognized for their impact on cellular mechanics and pathophysiology. Proteins involved in these disorders tend to misfold and form insoluble inclusions, via aberrant liquid–to-solid phase transitions within stress granules and other biomolecular condensates. Despite their importance, probing the viscoelastic properties of these heterogeneous assemblies in living cells remains challenging due to their small size and rapid molecular turnover. Building on our previous study on Brillouin frequency shifts, here we employ a stabilized Brillouin microscope to quantify the full width at half maximum of the Brillouin peak, revealing viscosity-related mechanical signatures of pathological condensates. Combined with FRAP, our analysis shows that ALS-related proteins form condensates with broader linewidths than physiological stress granules, indicating increased viscosity and a more solid-like state. These findings demonstrate that Brillouin linewidth imaging can distinguish liquid-like from solid-like condensates in situ and uncover dissipative mechanical alterations relevant to neurodegenerative disease mechanisms.
我们提出了一种无标记、高分辨率的方法来研究活细胞中的病理蛋白质聚集和异常相行为。与神经退行性疾病相关的细胞内蛋白聚集体因其对细胞力学和病理生理学的影响而日益被认识。在应力颗粒和其他生物分子凝聚物中,通过异常的液相到固相转变,参与这些疾病的蛋白质倾向于错误折叠并形成不溶性包裹体。尽管它们很重要,但由于它们的小尺寸和快速的分子周转,探测活细胞中这些异质组件的粘弹性特性仍然具有挑战性。在我们之前对布里渊频移的研究的基础上,我们在这里使用了一个稳定的布里渊显微镜来量化布里渊峰半最大值处的全宽度,揭示了病理凝析物与粘度相关的力学特征。结合FRAP,我们的分析表明,als相关蛋白形成的凝聚物比生理应激颗粒具有更宽的线宽,表明粘度增加,更像固体状态。这些发现表明,布里渊线宽成像可以原位区分液体状和固体状凝聚体,并揭示与神经退行性疾病机制相关的耗散力学改变。
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引用次数: 0
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IEEE Photonics Journal
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