Hpb最新文献

英文中文

Comment on: “Preoperative risk score (PreopScore) to predict overall survival after resection for hepatocellular carcinoma” 评论"预测肝细胞癌切除术后总生存率的术前风险评分（PreopScore）"。

IF 2.7 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Hpb

Pub Date : 2024-08-01 DOI: 10.1016/j.hpb.2024.05.003

引用次数: 0

Building the next generation of HPB surgeons: E-AHPBA Early Career Group, Online Academy, Mentorship Program, and Fellowships 培养下一代 HPB 外科医生：E-AHPBA早期职业小组、在线学院、导师计划和奖学金

IF 2.7 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Hpb

Pub Date : 2024-08-01 DOI: 10.1016/j.hpb.2024.05.007

引用次数: 0

European validation of the classification for the anticipated difficulty of liver transplantation 肝脏移植预期难度分类的欧洲验证

IF 2.7 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Hpb

Pub Date : 2024-08-01 DOI: 10.1016/j.hpb.2024.05.004

Background

Appropriate risk stratification for the difficulty of liver transplantation (LT) is essential to guide the selection and acceptance of grafts and avoid morbidity and mortality.

Methods

Based on 987 LTs collected from 5 centers, perioperative outcomes were analyzed across the 3 difficulty levels. Each LT was retrospectively scored from 0 to 10. Scores of 0–2, 3–5 and 6–10 were then translated into respective difficulty levels: low, moderate and high. Complications were reported according to the comprehensive complication index (CCI).

Results

The difficulty level of LT in 524 (53%), 323 (32%), and 140 (14%) patients was classified as low, moderate and high, respectively. The values of major intraoperative outcomes, such as cold ischemia time (p = 0.04) and operative time (p < 0.0001) increased gradually with statistically significant values among difficulty levels. There was a corresponding increase in CCI (p = 0.04), severe complication rates (p = 0.05) and length of ICU (p = 0.01) and hospital (p = 0.004) stays across the different difficulty levels.

Conclusion

The LT difficulty classification has been validated.

背景对肝移植（LT）难度进行适当的风险分层对于指导移植物的选择和接受以及避免发病率和死亡率至关重要。方法根据从 5 个中心收集的 987 例 LT，对 3 个难度级别的围手术期结果进行分析。每例LT均从0至10分进行回顾性评分。然后将 0-2、3-5 和 6-10 分分别转换成低、中和高难度级别。结果524例（53%）、323例（32%）和140例（14%）患者的LT难度分别为低、中和高。术中主要结果的数值，如冷缺血时间（p = 0.04）和手术时间（p < 0.0001）逐渐增加，不同难度的数值有统计学意义。不同难度级别的 CCI（p = 0.04）、严重并发症发生率（p = 0.05）以及重症监护室（p = 0.01）和住院（p = 0.004）时间也相应增加。

{"title":"European validation of the classification for the anticipated difficulty of liver transplantation","authors":"","doi":"10.1016/j.hpb.2024.05.004","DOIUrl":"10.1016/j.hpb.2024.05.004","url":null,"abstract":"<div><h3>Background</h3><p>Appropriate risk stratification<span> for the difficulty of liver transplantation (LT) is essential to guide the selection and acceptance of grafts and avoid morbidity and mortality.</span></p></div><div><h3>Methods</h3><p>Based on 987 LTs collected from 5 centers, perioperative outcomes were analyzed across the 3 difficulty levels. Each LT was retrospectively scored from 0 to 10. Scores of 0–2, 3–5 and 6–10 were then translated into respective difficulty levels: low, moderate and high. Complications were reported according to the comprehensive complication index (CCI).</p></div><div><h3>Results</h3><p>The difficulty level of LT in 524 (53%), 323 (32%), and 140 (14%) patients was classified as low, moderate and high, respectively. The values of major intraoperative outcomes, such as cold ischemia<span> time (p = 0.04) and operative time (p < 0.0001) increased gradually with statistically significant values among difficulty levels. There was a corresponding increase in CCI (p = 0.04), severe complication rates (p = 0.05) and length of ICU (p = 0.01) and hospital (p = 0.004) stays across the different difficulty levels.</span></p></div><div><h3>Conclusion</h3><p>The LT difficulty classification has been validated.</p></div>","PeriodicalId":13229,"journal":{"name":"Hpb","volume":"26 8","pages":"Pages 1033-1039"},"PeriodicalIF":2.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141051504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vein-guided anatomical resection of liver segment III along the left hepatic vein: a feasible procedure? 静脉引导下沿左肝静脉解剖切除肝 III 段：可行的手术方法？

IF 2.7 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Hpb

Pub Date : 2024-08-01 DOI: 10.1016/j.hpb.2024.05.002

引用次数: 0

Textbook oncologic outcomes among patients undergoing laparoscopic, robotic and open surgery for intrahepatic and perihilar cholangiocarcinoma 接受腹腔镜、机器人和开腹手术治疗肝内和肝周胆管癌的患者的教科书式肿瘤学结果

IF 2.7 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Hpb

Pub Date : 2024-08-01 DOI: 10.1016/j.hpb.2024.05.010

Background

Textbook oncologic outcome (TOO) serves as a composite, oncologic metric for surgical quality of care. We sought to evaluate variations in TOO among patients undergoing laparoscopic, robotic, and open surgery for intrahepatic (iCCA) and perihilar (pCCA) cholangiocarcinoma.

Methods

Patients who underwent liver resection for iCCA and pCCA between 2010 and 2018 were identified from the National Cancer Database. Entropy balancing was performed for covariate balancing and multivariable regression was used to evaluate the association between surgical approach and TOO.

Results

Among 5434 patients who underwent hepatic resection between 2010 and 2018, 3888 (71.6%) had iCCA, and 1546 (28.4%) had pCCA. TOO was achieved in 11.7% (n = 454), and 18.8% (n = 291) of patients with iCCA and pCCA, respectively. There was a difference in achievement of TOO relative to operative approach among patients with iCCA (robotic: 6.2% vs. laparoscopic: 8.1% vs. open: 12.5%; p = 0.002). After entropy balancing, patients with iCCA undergoing laparoscopic surgery had 32% reduced odds of achieving TOO (Ref: open surgery; laparoscopic, OR 0.68, 95%CI 0.49–0.93; p = 0.016; robotic, OR 0.69, 95%CI 0.34–1.39; p = 0.298).

Conclusions

Usage of composite oncologic measures such as TOO may allow for a holistic assessment of different approaches to hepatic resection among patients with CCA.

背景教科书肿瘤学结果（TOO）是衡量外科护理质量的综合肿瘤学指标。我们试图评估接受腹腔镜、机器人和开腹手术治疗肝内（iCCA）和肝周（pCCA）胆管癌的患者在TOO方面的差异。方法从国家癌症数据库中识别出2010年至2018年间接受肝切除术治疗iCCA和pCCA的患者。结果在 2010 年至 2018 年间接受肝切除术的 5434 例患者中，3888 例（71.6%）为 iCCA，1546 例（28.4%）为 pCCA。iCCA和pCCA患者中分别有11.7%（n = 454）和18.8%（n = 291）达到TOO。在iCCA患者中，实现TOO的手术方式存在差异（机器人：6.2% vs. 腹腔镜：8.1% vs. 开腹：12.5%；P = 0.002）。经过熵平衡后，接受腹腔镜手术的iCCA患者达到TOO的几率降低了32%（参考：开腹手术；腹腔镜，OR 0.68，95%CI 0.49-0.93；p = 0.016；机器人，OR 0.69，95%CI 0.34-1.39；p = 0.298）。

{"title":"Textbook oncologic outcomes among patients undergoing laparoscopic, robotic and open surgery for intrahepatic and perihilar cholangiocarcinoma","authors":"","doi":"10.1016/j.hpb.2024.05.010","DOIUrl":"10.1016/j.hpb.2024.05.010","url":null,"abstract":"<div><h3>Background</h3><p>Textbook oncologic outcome (TOO) serves as a composite, oncologic metric for surgical quality of care. We sought to evaluate variations in TOO among patients undergoing laparoscopic, robotic, and open surgery for intrahepatic (iCCA) and perihilar (pCCA) cholangiocarcinoma.</p></div><div><h3>Methods</h3><p>Patients who underwent liver resection for iCCA and pCCA between 2010 and 2018 were identified from the National Cancer Database. Entropy balancing was performed for covariate balancing and multivariable regression was used to evaluate the association between surgical approach and TOO.</p></div><div><h3>Results</h3><p>Among 5434 patients who underwent hepatic resection between 2010 and 2018, 3888 (71.6%) had iCCA, and 1546 (28.4%) had pCCA. TOO was achieved in 11.7% (n = 454), and 18.8% (n = 291) of patients with iCCA and pCCA, respectively. There was a difference in achievement of TOO relative to operative approach among patients with iCCA (robotic: 6.2% vs. laparoscopic: 8.1% vs. open: 12.5%; p = 0.002). After entropy balancing, patients with iCCA undergoing laparoscopic surgery had 32% reduced odds of achieving TOO (Ref: open surgery; laparoscopic, OR 0.68, 95%CI 0.49–0.93; p = 0.016; robotic, OR 0.69, 95%CI 0.34–1.39; p = 0.298).</p></div><div><h3>Conclusions</h3><p>Usage of composite oncologic measures such as TOO may allow for a holistic assessment of different approaches to hepatic resection among patients with CCA.</p></div>","PeriodicalId":13229,"journal":{"name":"Hpb","volume":"26 8","pages":"Pages 1051-1061"},"PeriodicalIF":2.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141135588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Highlights in this issue 本期亮点

IF 2.7 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Hpb

Pub Date : 2024-08-01 DOI: 10.1016/S1365-182X(24)02193-2

引用次数: 0

Improved outcomes of liver resection for hepatitis C-related hepatocellular carcinoma after the introduction of direct-acting antiviral therapy 引入直接作用抗病毒疗法后，丙型肝炎相关肝细胞癌肝脏切除术的疗效得到改善

IF 2.7 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Hpb

Pub Date : 2024-08-01 DOI: 10.1016/j.hpb.2024.04.014

Background

Assess impact of direct-acting antivirals introduction on outcomes after liver resection for hepatocellular carcinoma.

Methods

391 patients (1991–2021) treated with resection for hepatocellular carcinoma on Hepatitis C background were divided according to receiving Hepatitis C treatment, treatment type, achievement of sustained virological response (SVR), time of resection pre- (Era 1, 1991–2011) and post-direct acting antivirals introduction (Era 2, 2012–2021). Survival was estimated with Kaplan–Meier curves, Cox regression analysis performed to identify survival predictors.

Results

Majority of patients had single lesion (67.8%), diameter >2 cm in 60.6%, no evidence of macroscopic vascular invasion on imaging. Pathology showed vascular invasion in 69.6% of patients, 76.5% microvascular. Recurrence developed in 247 patients (63.2%). 194 patients (49.6%) achieved SVR. Overall survival at 1-, 3-, 5-years was 94.6%, 85.7%, 78.8% for patients who achieved SVR, 80.1%, 48.1%, 29.9% in those who did not (p < 0.001). 220 patients (56.3%) were in Era 1, 171 (43.7%) in Era 2. Survival at 1-, 3-, 5-years was 76.1%, 49%, 36% in Era 1, 94.5%, 82.5%, 70.3% in Era 2 (p < 0.001). SVR was an independent predictor of survival on multiple Cox Regression analysis.

Conclusion

While many aspects of HCC management have evolved, SVR following direct-acting antivirals independently improves HCC resection outcomes.

背景评估直接作用抗病毒药物的引入对肝细胞癌肝脏切除术后预后的影响。方法将391例（1991-2021年）丙肝背景肝细胞癌切除术患者按照接受丙肝治疗、治疗类型、获得持续病毒学应答（SVR）、切除术前（时代1，1991-2011年）和引入直接作用抗病毒药物后（时代2，2012-2021年）的时间进行分类。结果大多数患者为单发病灶（67.8%），60.6%的患者直径为2厘米，影像学检查未发现大血管侵犯。病理结果显示，69.6%的患者有血管侵犯，76.5%为微血管侵犯。247名患者（63.2%）出现复发。194名患者（49.6%）获得了SVR。获得 SVR 的患者 1、3、5 年的总生存率分别为 94.6%、85.7%、78.8%，未获得 SVR 的患者分别为 80.1%、48.1%、29.9%（p <0.001）。220名患者（56.3%）属于第一代，171名（43.7%）属于第二代。1、3、5 年生存率分别为：第一代 76.1%、49%、36%，第二代 94.5%、82.5%、70.3%（p <0.001）。结论虽然 HCC 治疗的许多方面都在不断发展，但使用直接作用抗病毒药物后 SVR 可独立改善 HCC 的切除效果。

{"title":"Improved outcomes of liver resection for hepatitis C-related hepatocellular carcinoma after the introduction of direct-acting antiviral therapy","authors":"","doi":"10.1016/j.hpb.2024.04.014","DOIUrl":"10.1016/j.hpb.2024.04.014","url":null,"abstract":"<div><h3>Background</h3><p><span>Assess impact of direct-acting antivirals introduction on outcomes after liver resection for </span>hepatocellular carcinoma.</p></div><div><h3>Methods</h3><p>391 patients (1991–2021) treated with resection for hepatocellular carcinoma on Hepatitis C background were divided according to receiving Hepatitis C treatment<span>, treatment type, achievement of sustained virological response (SVR), time of resection pre- (Era 1, 1991–2011) and post-direct acting antivirals introduction (Era 2, 2012–2021). Survival was estimated with Kaplan–Meier curves, Cox regression analysis performed to identify survival predictors.</span></p></div><div><h3>Results</h3><p>Majority of patients had single lesion (67.8%), diameter >2 cm in 60.6%, no evidence of macroscopic vascular invasion on imaging. Pathology showed vascular invasion in 69.6% of patients, 76.5% microvascular. Recurrence developed in 247 patients (63.2%). 194 patients (49.6%) achieved SVR. Overall survival at 1-, 3-, 5-years was 94.6%, 85.7%, 78.8% for patients who achieved SVR, 80.1%, 48.1%, 29.9% in those who did not (p < 0.001). 220 patients (56.3%) were in Era 1, 171 (43.7%) in Era 2. Survival at 1-, 3-, 5-years was 76.1%, 49%, 36% in Era 1, 94.5%, 82.5%, 70.3% in Era 2 (p < 0.001). SVR was an independent predictor of survival on multiple Cox Regression analysis.</p></div><div><h3>Conclusion</h3><p>While many aspects of HCC management have evolved, SVR following direct-acting antivirals independently improves HCC resection outcomes.</p></div>","PeriodicalId":13229,"journal":{"name":"Hpb","volume":"26 8","pages":"Pages 1007-1021"},"PeriodicalIF":2.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140882208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Healthcare cost expenditure for robotic versus laparoscopic liver resection: a bottom-up economic evaluation 机器人肝切除术与腹腔镜肝切除术的医疗成本支出：自下而上的经济评估

IF 2.7 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Hpb

Pub Date : 2024-08-01 DOI: 10.1016/j.hpb.2024.05.017

Background

Minimally invasive liver surgery (MILS) is increasingly performed via the robot-assisted approach but may be associated with increased costs. This study is a post-hoc comparison of healthcare cost expenditure for robotic liver resection (RLR) and laparoscopic liver resection (LLR) in a high-volume center.

Methods

In-hospital and 30-day postoperative healthcare costs were calculated per patient in a retrospective series (October 2015–December 2022).

Results

Overall, 298 patients were included (143 RLR and 155 LLR). Benefits of RLR were lower conversion rate (2.8% vs 12.3%, p = 0.002), shorter operating time (167 min vs 198 min, p = 0.044), and less blood loss (50 mL vs 200 mL, p < 0.001). Total per-procedure costs of RLR (€10260) and LLR (€9931) were not significantly different (mean difference €329 [95% bootstrapped confidence interval (BCI) €-1179–€2120]). Lower costs with RLR due to shorter surgical and operating room time were offset by higher disposable instrumentation costs resulting in comparable intraoperative costs (€5559 vs €5247, mean difference €312 [95% BCI €-25–€648]). Postoperative costs were similar for RLR (€4701) and LLR (€4684), mean difference €17 [95% BCI €-1357–€1727]. When also considering purchase and maintenance costs, RLR resulted in higher total per-procedure costs.

Discussion

In a high-volume center, RLR can have similar per-procedure cost expenditure as LLR when disregarding capital investment.

微创肝脏手术（MILS）越来越多地通过机器人辅助方法进行，但可能会导致成本增加。本研究比较了一个高流量中心的机器人肝脏切除术（RLR）和腹腔镜肝脏切除术（LLR）的医疗成本支出。通过回顾性系列研究（2015 年 10 月至 2022 年 12 月）计算了每位患者的住院和术后 30 天的医疗成本。共纳入 298 例患者（143 例 RLR 和 155 例 LLR）。RLR的优点是转化率较低（2.8% vs 12.3%，p = 0.002），手术时间较短（167 分钟 vs 198 分钟，p = 0.044），失血较少（50 毫升 vs 200 毫升，p < 0.001）。RLR（10260 欧元）和 LLR（9931 欧元）的每次手术总费用没有显著差异（平均差异为 329 欧元[95% 引导置信区间 (BCI) 为 1179 欧元-2120 欧元]）。由于手术和手术室时间较短，RLR 的成本较低，但一次性器械成本较高，因此术中成本相当（5559 欧元 vs 5247 欧元，平均差异为 312 欧元 [95% BCI €-25-648]）。RLR（4701 欧元）和 LLR（4684 欧元）的术后成本相似，平均差异为 17 欧元[95% BCI 1357 欧元-1727 欧元]。如果同时考虑购买和维护成本，RLR 的每次手术总成本更高。在高产量中心，如果不考虑资本投资，RLR 的每例手术成本支出可能与 LLR 相似。

{"title":"Healthcare cost expenditure for robotic versus laparoscopic liver resection: a bottom-up economic evaluation","authors":"","doi":"10.1016/j.hpb.2024.05.017","DOIUrl":"10.1016/j.hpb.2024.05.017","url":null,"abstract":"<div><h3>Background</h3><p>Minimally invasive liver surgery (MILS) is increasingly performed via the robot-assisted approach but may be associated with increased costs. This study is a <em>post-hoc</em> comparison of healthcare cost expenditure for robotic liver resection (RLR) and laparoscopic liver resection (LLR) in a high-volume center.</p></div><div><h3>Methods</h3><p>In-hospital and 30-day postoperative healthcare costs were calculated per patient in a retrospective series (October 2015–December 2022).</p></div><div><h3>Results</h3><p>Overall, 298 patients were included (143 RLR and 155 LLR). Benefits of RLR were lower conversion rate (2.8% vs 12.3%, p = 0.002), shorter operating time (167 min vs 198 min, p = 0.044), and less blood loss (50 mL vs 200 mL, p < 0.001). Total per-procedure costs of RLR (€10260) and LLR (€9931) were not significantly different (mean difference €329 [95% bootstrapped confidence interval (BCI) €-1179–€2120]). Lower costs with RLR due to shorter surgical and operating room time were offset by higher disposable instrumentation costs resulting in comparable intraoperative costs (€5559 vs €5247, mean difference €312 [95% BCI €-25–€648]). Postoperative costs were similar for RLR (€4701) and LLR (€4684), mean difference €17 [95% BCI €-1357–€1727]. When also considering purchase and maintenance costs, RLR resulted in higher total per-procedure costs.</p></div><div><h3>Discussion</h3><p>In a high-volume center, RLR can have similar per-procedure cost expenditure as LLR when disregarding capital investment.</p></div>","PeriodicalId":13229,"journal":{"name":"Hpb","volume":"26 8","pages":"Pages 971-980"},"PeriodicalIF":2.7,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1365182X2401743X/pdfft?md5=f7026679ac5183323aba6ab310a4aae5&pid=1-s2.0-S1365182X2401743X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141254375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reproducibility and efficiency of liver volumetry using manual method and liver analysis software 使用手动方法和肝脏分析软件进行肝脏体积测量的重现性和效率

IF 2.7 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Hpb

Pub Date : 2024-07-01 DOI: 10.1016/j.hpb.2024.03.1157

Harufumi Maki, Yujiro Nishioka, Antony Haddad, Mateo Lendoire, Hop S. Tran Cao, Yun S. Chun, Ching-Wei D. Tzeng, Jean-Nicolas Vauthey, Timothy E. Newhook

Background

For liver volumetry, manual tracing on computed tomography (CT) images is time-consuming and operator dependent. To overcome these disadvantages, several three-dimensional simulation software programs have been developed; however, their efficacy has not fully been evaluated.

Methods

Three physicians performed liver volumetry on preoperative CT images on 30 patients who underwent formal right hepatectomy, using manual tracing volumetry and two simulation software programs, SYNAPSE and syngo.via. The future liver remnant (FLR) was calculated using each method of volumetry. The primary endpoint was reproducibility and secondary outcomes were calculation time and learning curve.

Results

The mean FLR was significantly lower for manual volumetry than for SYNAPSE or syngo.via; there was no significant difference in mean FLR between the two software-based methods. Reproducibility was lower for the manual method than for the software-based methods. Mean calculation time was shortest for SYNAPSE. For the two physicians unfamiliar with the software, no obvious learning curve was observed for using SYNAPSE, whereas learning curves were observed for using syngo.via.

Conclusions

Liver volumetry was more reproducible and faster with three-dimensional simulation software, especially SYNAPSE software, than with the conventional manual tracing method. Software can help even inexperienced physicians learn quickly how to perform liver volumetry.

背景对于肝脏体积测量，在计算机断层扫描（CT）图像上手动描记既费时又依赖于操作者。方法三位医生对 30 位接受正规右肝切除术的患者的术前 CT 图像进行了肝脏容积测量，分别使用了手动描记容积法和两个模拟软件程序 SYNAPSE 和 syngo.via。每种体积测量方法都计算了未来肝脏残余（FLR）。主要终点是再现性，次要结果是计算时间和学习曲线。结果手动容积测量法的平均FLR显著低于SYNAPSE或syngo.via；两种软件方法的平均FLR没有显著差异。手动方法的再现性低于软件方法。SYNAPSE 的平均计算时间最短。结论与传统的手动描记方法相比，使用三维模拟软件，尤其是 SYNAPSE 软件进行肝脏体积测量的可重复性更高，速度更快。软件可以帮助缺乏经验的医生快速学会如何进行肝脏体积测量。

{"title":"Reproducibility and efficiency of liver volumetry using manual method and liver analysis software","authors":"Harufumi Maki, Yujiro Nishioka, Antony Haddad, Mateo Lendoire, Hop S. Tran Cao, Yun S. Chun, Ching-Wei D. Tzeng, Jean-Nicolas Vauthey, Timothy E. Newhook","doi":"10.1016/j.hpb.2024.03.1157","DOIUrl":"10.1016/j.hpb.2024.03.1157","url":null,"abstract":"<div><h3>Background</h3><p>For liver volumetry, manual tracing on computed tomography (CT) images is time-consuming and operator dependent. To overcome these disadvantages, several three-dimensional simulation software programs have been developed; however, their efficacy has not fully been evaluated.</p></div><div><h3>Methods</h3><p>Three physicians performed liver volumetry on preoperative CT images on 30 patients who underwent formal right hepatectomy, using manual tracing volumetry and two simulation software programs, SYNAPSE and syngo.via. The future liver remnant (FLR) was calculated using each method of volumetry. The primary endpoint was reproducibility and secondary outcomes were calculation time and learning curve.</p></div><div><h3>Results</h3><p>The mean FLR was significantly lower for manual volumetry than for SYNAPSE or syngo.via; there was no significant difference in mean FLR between the two software-based methods. Reproducibility was lower for the manual method than for the software-based methods. Mean calculation time was shortest for SYNAPSE. For the two physicians unfamiliar with the software, no obvious learning curve was observed for using SYNAPSE, whereas learning curves were observed for using syngo.via.</p></div><div><h3>Conclusions</h3><p>Liver volumetry was more reproducible and faster with three-dimensional simulation software, especially SYNAPSE software, than with the conventional manual tracing method. Software can help even inexperienced physicians learn quickly how to perform liver volumetry.</p></div>","PeriodicalId":13229,"journal":{"name":"Hpb","volume":"26 7","pages":"Pages 911-918"},"PeriodicalIF":2.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140269885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letter to editor: “opioid analgesia and severity of acute pancreatitis: an international multicentre cohort study on pain management in acute pancreatitis” 致编辑的信："阿片类药物镇痛与急性胰腺炎的严重程度：一项关于急性胰腺炎疼痛治疗的国际多中心队列研究"

IF 2.7 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Hpb

Pub Date : 2024-07-01 DOI: 10.1016/j.hpb.2024.04.006

Shuang-Mei Dai, Tao Guo

引用次数: 0

首页上一页

类型

全部化学•材料生命科学医学物理工程技术环境•农林材料科学地球科学法学管理学化学环境科学与生态学计算机科学教育学经济学农林科学人文科学生物学数学物理与天体物理心理学综合性期刊其他工业工程理学历史学农学文学信息工程

数据库

全部 ACS Publications Elsevier ieeexplore Springer The Royal Society of Chemistry Wiley

期刊

Hpb

全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.

﹀