Pub Date : 2022-01-01DOI: 10.56042/ijnpr.v12i4.29108
A. Kaur, A. Shukla, R. Shukla
Ehretia acuminata is native to Southeast Asia, America, and Africa. It is commonly used as fodder and in quite a variety of medicinal applications. E. acuminata is widely used in India, but there are few reports in the literature of studies on its biological properties. In this study, the antidiabetic and anti-inflammatory activities of plant E. acuminata was evaluated. The antidiabetic activity of the different extracts was measured by α -amylase and α -glycosidase inhibition method. The anti-inflammatory activity was evaluated by the egg albumin of hen. Petroleum ether, chloroform, ethyl acetate, ethanol and water extracts of bark of E. acuminata was evaluated for in-vitro anti-inflammatory and antidiabetic activity. Ethyl acetate and ethanol extract showed significant anti-inflammatory effects (IC 50 170 and 172 µg/mL respectively). Chloroform is the only extract that showed significant inhibition against the antidiabetic effect (IC 50 42-45 µg/mL). The findings suggest that the bark of E. acuminata contains potential antidiabetic and anti-inflammatory compounds, which could be tested as drug candidates against diabetic and inflammation-related pathological processes in medicinal chemistry studies. flavone derivative ovalifolia
{"title":"In vitro antidiabetic and anti-inflammatory activities of the bark of Ehretia acuminata R.Br.","authors":"A. Kaur, A. Shukla, R. Shukla","doi":"10.56042/ijnpr.v12i4.29108","DOIUrl":"https://doi.org/10.56042/ijnpr.v12i4.29108","url":null,"abstract":"Ehretia acuminata is native to Southeast Asia, America, and Africa. It is commonly used as fodder and in quite a variety of medicinal applications. E. acuminata is widely used in India, but there are few reports in the literature of studies on its biological properties. In this study, the antidiabetic and anti-inflammatory activities of plant E. acuminata was evaluated. The antidiabetic activity of the different extracts was measured by α -amylase and α -glycosidase inhibition method. The anti-inflammatory activity was evaluated by the egg albumin of hen. Petroleum ether, chloroform, ethyl acetate, ethanol and water extracts of bark of E. acuminata was evaluated for in-vitro anti-inflammatory and antidiabetic activity. Ethyl acetate and ethanol extract showed significant anti-inflammatory effects (IC 50 170 and 172 µg/mL respectively). Chloroform is the only extract that showed significant inhibition against the antidiabetic effect (IC 50 42-45 µg/mL). The findings suggest that the bark of E. acuminata contains potential antidiabetic and anti-inflammatory compounds, which could be tested as drug candidates against diabetic and inflammation-related pathological processes in medicinal chemistry studies. flavone derivative ovalifolia","PeriodicalId":13297,"journal":{"name":"Indian Journal of Natural Products and Resources","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70703868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.56042/ijnpr.v13i3.38114
{"title":"Isolation and identification of thermo stable multi catalytic Bacillus licheniformis strain V7 from Ganeshpuri hot spring","authors":"","doi":"10.56042/ijnpr.v13i3.38114","DOIUrl":"https://doi.org/10.56042/ijnpr.v13i3.38114","url":null,"abstract":"","PeriodicalId":13297,"journal":{"name":"Indian Journal of Natural Products and Resources","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70704135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.56042/ijnpr.v13i2.37958
{"title":"Ananas comosus peel waste, a novel substrate of therapeutic potential: Evidences and prospects","authors":"","doi":"10.56042/ijnpr.v13i2.37958","DOIUrl":"https://doi.org/10.56042/ijnpr.v13i2.37958","url":null,"abstract":"","PeriodicalId":13297,"journal":{"name":"Indian Journal of Natural Products and Resources","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70704194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.56042/ijnpr.v13i3.50452
{"title":"Fodder plants and foraging behaviour of Asian elephants in Srivilliputhur Elephant Reserve, Tamil Nadu, India","authors":"","doi":"10.56042/ijnpr.v13i3.50452","DOIUrl":"https://doi.org/10.56042/ijnpr.v13i3.50452","url":null,"abstract":"","PeriodicalId":13297,"journal":{"name":"Indian Journal of Natural Products and Resources","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70704213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.56042/ijnpr.v13i3.51382
{"title":"A comparative study on quality characteristics of cookies incorporated with roasted chicory powder and inulin as sugar replacers","authors":"","doi":"10.56042/ijnpr.v13i3.51382","DOIUrl":"https://doi.org/10.56042/ijnpr.v13i3.51382","url":null,"abstract":"","PeriodicalId":13297,"journal":{"name":"Indian Journal of Natural Products and Resources","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70704231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.56042/ijnpr.v13i1.42546
Manish, Brindha Durairaj
The study aimed to investigate bioactive phytochemicals and antioxidant activity of Elaeocarpus tectorius (Lour.) Poir leaf extract. The antioxidant properties were evaluated by four antioxidant methods, 2,2-diphenyl-1-picryl-hydrazyl-hydrate assay, hydroxyl radical (HO%) scavenging assay, superoxide anion (O2%) radical scavenging assay, and nitric oxide (NO%) scavenging assay. The free radical scavenging activity of hydroethanolic extract of E. tectorius was found to be high for DPPH, nitric oxide, superoxide, and hydrogen peroxide (H 2 O 2 ) radicals in a concentration-dependent manner. The content of total phenols, flavonoids, and tannins was also high in the hydroethanolic extract. The antioxidant capacity and total phenolic content were shown to be significantly related, indicating that phenolic chemicals are the primary contributors to plants' antioxidant capabilities. Based on the findings, it can be concluded that the hydroethanolic leaf extract of E. tectorius could serve as a potential source of antioxidants and can be explored as a therapeutic agent in free radical-induced diseases.
{"title":"In vitro antioxidant activity of Elaeocarpus tectorius (Lour.) Poir – an Indian medicinal plant","authors":"Manish, Brindha Durairaj","doi":"10.56042/ijnpr.v13i1.42546","DOIUrl":"https://doi.org/10.56042/ijnpr.v13i1.42546","url":null,"abstract":"The study aimed to investigate bioactive phytochemicals and antioxidant activity of Elaeocarpus tectorius (Lour.) Poir leaf extract. The antioxidant properties were evaluated by four antioxidant methods, 2,2-diphenyl-1-picryl-hydrazyl-hydrate assay, hydroxyl radical (HO%) scavenging assay, superoxide anion (O2%) radical scavenging assay, and nitric oxide (NO%) scavenging assay. The free radical scavenging activity of hydroethanolic extract of E. tectorius was found to be high for DPPH, nitric oxide, superoxide, and hydrogen peroxide (H 2 O 2 ) radicals in a concentration-dependent manner. The content of total phenols, flavonoids, and tannins was also high in the hydroethanolic extract. The antioxidant capacity and total phenolic content were shown to be significantly related, indicating that phenolic chemicals are the primary contributors to plants' antioxidant capabilities. Based on the findings, it can be concluded that the hydroethanolic leaf extract of E. tectorius could serve as a potential source of antioxidants and can be explored as a therapeutic agent in free radical-induced diseases.","PeriodicalId":13297,"journal":{"name":"Indian Journal of Natural Products and Resources","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70704393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.56042/ijnpr.v13i2.43786
{"title":"Phytochemical screening and antifungal activity in vitro of Trichilia hirta L. fruit extracts against clinical isolates of Candida spp.","authors":"","doi":"10.56042/ijnpr.v13i2.43786","DOIUrl":"https://doi.org/10.56042/ijnpr.v13i2.43786","url":null,"abstract":"","PeriodicalId":13297,"journal":{"name":"Indian Journal of Natural Products and Resources","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70704413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.56042/ijnpr.v13i2.47499
{"title":"Antioxidant and antimicrobial potential of Canavalia gladiata (Jacq.) DC. leaves and seeds: GC-MS based metabolic profiling","authors":"","doi":"10.56042/ijnpr.v13i2.47499","DOIUrl":"https://doi.org/10.56042/ijnpr.v13i2.47499","url":null,"abstract":"","PeriodicalId":13297,"journal":{"name":"Indian Journal of Natural Products and Resources","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70704422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.56042/ijnpr.v13i4.48344
{"title":"Anti-diabetic potential of fruit extracts of Flacourtia indica (Burm. F.) Merr-An in-vitro study","authors":"","doi":"10.56042/ijnpr.v13i4.48344","DOIUrl":"https://doi.org/10.56042/ijnpr.v13i4.48344","url":null,"abstract":"","PeriodicalId":13297,"journal":{"name":"Indian Journal of Natural Products and Resources","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70704653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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