Pub Date : 2022-07-15DOI: 10.18231/j.ijmr.2022.024
S. Kar, Snigdha Singh, Pragyan Parimita, A. Mishra, P. Panda
Needle stick injuries are preventable causes of fearsome diseases like Hepatitis B and HIV. In spite of this knowledge, the health care providers are quite negligent, and the institutional support too is compromised due to the increased demand for services. The current study is a dipstick audit of the knowledge and practices on NSI (prevention and management) among exposed health care workers, with specific reference to HIV infection in a private health facility in Bhubaneswar city, using an unorthodox tool of Focus Group Discussions among the participants.: The exercise was a part of the academic activity of health promotion on World AIDS Day 2021. Health care workers such as doctors, paramedical staff & utility staff voluntarily participated in the FGD session. Total 3 FGDs were conducted at 3 different places inside the hospital premises. Three moderators were selected previously and after discussing the theme of World AIDS Day, they guided the FGDs with similar probing questionnaires. The sessions were recorded with the help of a recorder and also noted down along with Sociograms. The data gave a real picture of how even premier institutions are complacent regarding the problem. Only 27% knew about the SOPs, and in none of the stations,SOPs were displayed or a register was maintained regarding NSI in their work area. None of the participants were aware of Post Exposure Prophylaxis for the same. This indeed highlighted an ignored aspect of quality health care. The data was an eye-opener in a tertiary care center and from time to time there should be refresher training or sessions to increase the level of awareness.
{"title":"Awareness regarding prevention and management of needle stick injury among the health care providers in a tertiary care Hospital, Bhubaneswar, Odisha- A qualitative data exploration","authors":"S. Kar, Snigdha Singh, Pragyan Parimita, A. Mishra, P. Panda","doi":"10.18231/j.ijmr.2022.024","DOIUrl":"https://doi.org/10.18231/j.ijmr.2022.024","url":null,"abstract":"Needle stick injuries are preventable causes of fearsome diseases like Hepatitis B and HIV. In spite of this knowledge, the health care providers are quite negligent, and the institutional support too is compromised due to the increased demand for services. The current study is a dipstick audit of the knowledge and practices on NSI (prevention and management) among exposed health care workers, with specific reference to HIV infection in a private health facility in Bhubaneswar city, using an unorthodox tool of Focus Group Discussions among the participants.: The exercise was a part of the academic activity of health promotion on World AIDS Day 2021. Health care workers such as doctors, paramedical staff & utility staff voluntarily participated in the FGD session. Total 3 FGDs were conducted at 3 different places inside the hospital premises. Three moderators were selected previously and after discussing the theme of World AIDS Day, they guided the FGDs with similar probing questionnaires. The sessions were recorded with the help of a recorder and also noted down along with Sociograms. The data gave a real picture of how even premier institutions are complacent regarding the problem. Only 27% knew about the SOPs, and in none of the stations,SOPs were displayed or a register was maintained regarding NSI in their work area. None of the participants were aware of Post Exposure Prophylaxis for the same. This indeed highlighted an ignored aspect of quality health care. The data was an eye-opener in a tertiary care center and from time to time there should be refresher training or sessions to increase the level of awareness.","PeriodicalId":13428,"journal":{"name":"Indian Journal of Microbiology Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81424063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-15DOI: 10.18231/j.ijmr.2022.026
Ranadive Ananth Govindaraju, Gayathri Parivallal, A. Nagalingam, Sumitha Devarajan
Waste water treatment system plays a vital role in controlling pollution of natural water bodies like lake, pond, river etc., by Municipal and Industrial effluents. Different industrial effluents play its own role in contaminating the water bodies which in turn creates huge impact for aquatic and terrestrial life. From past studies we understood that, all the sewage treatment systems have a secondary treatment step which are mainly driven by Bacterial oxidation or in other terms can be pronounced as Biological augmentation, Biological calcification etc., In environmental engineering term this bacterial growth will be pronounced as MLSS (Mixed Liquor Suspended Solids) and MLVSS (Mixed Liquor Volatile Suspended Solids). MLVSS will be an inclusive part of the MLSS and also can be sorted as live bacterial cells which can really does the oxidation process in the secondary treatment step of Sewage treatment plant. Hence, this study was performed to evaluate the percentage or concentration of MLVSS available in the total value of MLSS. For this study aeration tank water samples were collected from 6 different STP capacities from 6 different areas. All the samples were tested for MLSS and MLVSS concentration with the available standard method of drying. Drying with 105° C in oven gives the value of MLSS and drying with 550° C in furnace gives the value of MLVSS. With all the tested samples the concentration of MLVSS from the total MLSS was evaluated and standardized.
{"title":"MLVSS / MLSS ratio’s standard value obtained from different aeration tank samples of different capacity sewage treatment plant - A case study","authors":"Ranadive Ananth Govindaraju, Gayathri Parivallal, A. Nagalingam, Sumitha Devarajan","doi":"10.18231/j.ijmr.2022.026","DOIUrl":"https://doi.org/10.18231/j.ijmr.2022.026","url":null,"abstract":"Waste water treatment system plays a vital role in controlling pollution of natural water bodies like lake, pond, river etc., by Municipal and Industrial effluents. Different industrial effluents play its own role in contaminating the water bodies which in turn creates huge impact for aquatic and terrestrial life. From past studies we understood that, all the sewage treatment systems have a secondary treatment step which are mainly driven by Bacterial oxidation or in other terms can be pronounced as Biological augmentation, Biological calcification etc., In environmental engineering term this bacterial growth will be pronounced as MLSS (Mixed Liquor Suspended Solids) and MLVSS (Mixed Liquor Volatile Suspended Solids). MLVSS will be an inclusive part of the MLSS and also can be sorted as live bacterial cells which can really does the oxidation process in the secondary treatment step of Sewage treatment plant. Hence, this study was performed to evaluate the percentage or concentration of MLVSS available in the total value of MLSS. For this study aeration tank water samples were collected from 6 different STP capacities from 6 different areas. All the samples were tested for MLSS and MLVSS concentration with the available standard method of drying. Drying with 105° C in oven gives the value of MLSS and drying with 550° C in furnace gives the value of MLVSS. With all the tested samples the concentration of MLVSS from the total MLSS was evaluated and standardized.","PeriodicalId":13428,"journal":{"name":"Indian Journal of Microbiology Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89648921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-15DOI: 10.18231/j.ijmr.2022.019
Mitra Molaee Parvarei, A. Mortazavian
Cancer is a cellular disorder caused by changes in the mechanisms that control cell growth and differentiation. Breast cancer is the second most common cancer in women following lung cancer. Today, due to the side effects of treatment methods, many efforts have been made to discover natural compounds with a selective power in limiting cancers. This study was performed to investigate the cytotoxicity effects of paraprobiotic yogurt on breast and rectal cancer cell lines (MDA-Md, SKBR3, and SW 480). After culturing and amplifying the cancer cell line to determine the effect of supernatant toxicity, these cells were exposed to different doses of paraprobiotic supernatant, which was performed after 72 hours of MTT assay. According to the results, after adding different dilutions of paraprobiotic yogurt supernatant, YB-B could significantly inhibit the cell viability in three categories of cancer cells (MDA-Md, SKBR3, and SW 480) and had the greatest impact on SKBR3 (p≤0.05). The effects of cytotoxicity increased with elevating the concentration of the extract with the highest percentage of growth inhibition being related to the concentrations of 1/4, 1/3, and 1/2 (p = 0.05 and p = 0.01), respectively. Thus, the use of paraprobiotic yogurt supernatant as an effective substance in the treatment of cancer is recommended. Accordingly, future research could explore its substances to be potentially used in the treatment of cancer.
{"title":"Cytotoxic effect of paraprobiotic yogurts on cancer cell lines","authors":"Mitra Molaee Parvarei, A. Mortazavian","doi":"10.18231/j.ijmr.2022.019","DOIUrl":"https://doi.org/10.18231/j.ijmr.2022.019","url":null,"abstract":"Cancer is a cellular disorder caused by changes in the mechanisms that control cell growth and differentiation. Breast cancer is the second most common cancer in women following lung cancer. Today, due to the side effects of treatment methods, many efforts have been made to discover natural compounds with a selective power in limiting cancers. This study was performed to investigate the cytotoxicity effects of paraprobiotic yogurt on breast and rectal cancer cell lines (MDA-Md, SKBR3, and SW 480). After culturing and amplifying the cancer cell line to determine the effect of supernatant toxicity, these cells were exposed to different doses of paraprobiotic supernatant, which was performed after 72 hours of MTT assay. According to the results, after adding different dilutions of paraprobiotic yogurt supernatant, YB-B could significantly inhibit the cell viability in three categories of cancer cells (MDA-Md, SKBR3, and SW 480) and had the greatest impact on SKBR3 (p≤0.05). The effects of cytotoxicity increased with elevating the concentration of the extract with the highest percentage of growth inhibition being related to the concentrations of 1/4, 1/3, and 1/2 (p = 0.05 and p = 0.01), respectively. Thus, the use of paraprobiotic yogurt supernatant as an effective substance in the treatment of cancer is recommended. Accordingly, future research could explore its substances to be potentially used in the treatment of cancer.","PeriodicalId":13428,"journal":{"name":"Indian Journal of Microbiology Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90581141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-15DOI: 10.18231/j.ijmr.2022.027
Ranadive Ananth Govindaraju, Gayathri Parivallal, A. Nagalingam, Sumitha Devarajan
Sewage treatment system considered to be an inevitable step to handle the burgeoning water scarcity in the recent years. In this study a 1 MLD (Million Litres per Day) sewage treatment plant was selected and evaluated its performance efficiency for a period of 8 Weeks (02.10.2021 to 20.11.2021). The adapted treatment technology was Moving bed Bioreactor (MBBR) which is an attached biological growth method. This technology totally driven by MBBR Carrier media, which provides an enormous surface area for the microbial attachment. The treatment system has the following units such as Bar screen chamber, Grit Chamber, Oil & Grease Chamber, Equalization Tank, Anoxic Tank, MBBR Tank, Settling Tank, Filter Feed Tank, Pressure Sand Filter (PSF), Activated Carbon Filter (ACF), Chlorine dosing and Treated Water Tank. Water samples were collected from different treatment units for 10 days and analysed for the major water quality parameters such as Biochemical oxygen demand (BOD), Chemical oxygen demand (COD), Total Kjeldhals Nitrogen (TKN) and Total suspended solids (TSS). The analysis showed that all treated water parameters meet the State Pollution board standards. Also the results were very much useful to prepare a Standard Operating Procedure (SOP) which helps in hindrance free Operation and Maintenance of the system.
{"title":"Performance evaluation of 1 MLD MBBR type sewage treatment plant","authors":"Ranadive Ananth Govindaraju, Gayathri Parivallal, A. Nagalingam, Sumitha Devarajan","doi":"10.18231/j.ijmr.2022.027","DOIUrl":"https://doi.org/10.18231/j.ijmr.2022.027","url":null,"abstract":"Sewage treatment system considered to be an inevitable step to handle the burgeoning water scarcity in the recent years. In this study a 1 MLD (Million Litres per Day) sewage treatment plant was selected and evaluated its performance efficiency for a period of 8 Weeks (02.10.2021 to 20.11.2021). The adapted treatment technology was Moving bed Bioreactor (MBBR) which is an attached biological growth method. This technology totally driven by MBBR Carrier media, which provides an enormous surface area for the microbial attachment. The treatment system has the following units such as Bar screen chamber, Grit Chamber, Oil & Grease Chamber, Equalization Tank, Anoxic Tank, MBBR Tank, Settling Tank, Filter Feed Tank, Pressure Sand Filter (PSF), Activated Carbon Filter (ACF), Chlorine dosing and Treated Water Tank. Water samples were collected from different treatment units for 10 days and analysed for the major water quality parameters such as Biochemical oxygen demand (BOD), Chemical oxygen demand (COD), Total Kjeldhals Nitrogen (TKN) and Total suspended solids (TSS). The analysis showed that all treated water parameters meet the State Pollution board standards. Also the results were very much useful to prepare a Standard Operating Procedure (SOP) which helps in hindrance free Operation and Maintenance of the system.","PeriodicalId":13428,"journal":{"name":"Indian Journal of Microbiology Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90987023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-15DOI: 10.18231/j.ijmr.2022.015
B. Trivedi
(L.) is a popularly employed for medicinal plant for the treatment of various affilictions. The plant restrains glucoside, ellagic acid, isoquercetin, kaempferol, anthocyanins and myricetin as its primarily active constituents. These active constituents isoquercetin, kaempferol tituents impart multiple pharmacological activities to the plant which includes antidiabetic, antioxidant, antibacterial and antifungal activity. The present review confers precise information on phytochemical constituents, traditional uses and pharmacological actions of (L.).
{"title":"A review: Phytochemical and pharmacological analysis of medicinal plant","authors":"B. Trivedi","doi":"10.18231/j.ijmr.2022.015","DOIUrl":"https://doi.org/10.18231/j.ijmr.2022.015","url":null,"abstract":"(L.) is a popularly employed for medicinal plant for the treatment of various affilictions. The plant restrains glucoside, ellagic acid, isoquercetin, kaempferol, anthocyanins and myricetin as its primarily active constituents. These active constituents isoquercetin, kaempferol tituents impart multiple pharmacological activities to the plant which includes antidiabetic, antioxidant, antibacterial and antifungal activity. The present review confers precise information on phytochemical constituents, traditional uses and pharmacological actions of (L.).","PeriodicalId":13428,"journal":{"name":"Indian Journal of Microbiology Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80219036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-15DOI: 10.18231/j.ijmr.2022.020
Parul Sharma, Gopal Chauhan
Coronavirus has caused many outbreaks in the past. Two major outbreaks reported are SARS-CoV in China in the year 2003 and MERS-CoV in 2012 in the Middle East. The present outbreak of SARS-CoV-2 originated from a seafood market in Wuhan city of China in December 2019 with most common manifestation of atypical pneumonia. WHO declared it as a pandemic on 11th March 2020. Many newer strains of the virus have been identified so far and multiple diagnostic and therapeutic interventions have been tried to contain the spread. This virus is mutating very fast and causing huge loss of human lives and economy. Keeping in view the limited knowledge of the disease, it becomes necessary to take all protective measures to overcome the current pandemic and to prepare strategies to mitigate the future challenges.
{"title":"Two years of COVID-19: Challenges, opportunities and the way forward","authors":"Parul Sharma, Gopal Chauhan","doi":"10.18231/j.ijmr.2022.020","DOIUrl":"https://doi.org/10.18231/j.ijmr.2022.020","url":null,"abstract":"Coronavirus has caused many outbreaks in the past. Two major outbreaks reported are SARS-CoV in China in the year 2003 and MERS-CoV in 2012 in the Middle East. The present outbreak of SARS-CoV-2 originated from a seafood market in Wuhan city of China in December 2019 with most common manifestation of atypical pneumonia. WHO declared it as a pandemic on 11th March 2020. Many newer strains of the virus have been identified so far and multiple diagnostic and therapeutic interventions have been tried to contain the spread. This virus is mutating very fast and causing huge loss of human lives and economy. Keeping in view the limited knowledge of the disease, it becomes necessary to take all protective measures to overcome the current pandemic and to prepare strategies to mitigate the future challenges.","PeriodicalId":13428,"journal":{"name":"Indian Journal of Microbiology Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87425579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-15DOI: 10.18231/j.ijmr.2022.021
Kamaljeet, Naveen R. Saxena, Mohit Thalquotra
Although, bacteria have been considered as most common cause of healthcare associated infections (HCAI), however recent years have witnessed increased isolation of fungal pathogens. species, Mucorales, spp., spp. and spp. are predominant fungal pathogens isolated from cases of HCAI. As compared to bacterial nosocomial infections, fungal infections are generally difficult to diagnose and treat. Nosocomial mycoses are associated with high mortality and morbidity. The present study was conducted in the tertiary care academic hospital with an aim to identify filamentous fungal pathogen isolated from HCAI and study its antifungal susceptibility profile. Filamentous fungi isolated from cases of HCAI from intensive care unit (MICU) were included. They were identified by standard mycological techniques and antifungal susceptibility profile was studied. Out of 50 fungal pathogens, spp. were isolated from 21 (42%) cases, whereas 29 (58%) isolates were filamentous fungi. spp. (51.7%) were predominant among filamentous fungal pathogen. (27.6%) was the predominant isolate. Use of broad-spectrum antibiotics followed by neutropenia and presence of indwelling medical devices were common risk factors associated with HCAI due to filamentous fungi. Amphotericin B resistance was observed in 6.9% of isolates whereas 33.3% were resistant to fluconazole. Invasive fungal infection (IFI) though less common is associated with increased morbidity and mortality in patients admitted to ICU. Neutropenia and use of broad spectrum antibiotics are important risk factors for IFI. is the most common filamentous fungus cause of IFI. More emphasis should be given on rapid diagnosis, prompt treatment and strict compliance with infection prevention and control practices.
{"title":"Identification and antifungal susceptibility profile of filamentous fungi isolated from cases of healthcare associated infections","authors":"Kamaljeet, Naveen R. Saxena, Mohit Thalquotra","doi":"10.18231/j.ijmr.2022.021","DOIUrl":"https://doi.org/10.18231/j.ijmr.2022.021","url":null,"abstract":"Although, bacteria have been considered as most common cause of healthcare associated infections (HCAI), however recent years have witnessed increased isolation of fungal pathogens. species, Mucorales, spp., spp. and spp. are predominant fungal pathogens isolated from cases of HCAI. As compared to bacterial nosocomial infections, fungal infections are generally difficult to diagnose and treat. Nosocomial mycoses are associated with high mortality and morbidity. The present study was conducted in the tertiary care academic hospital with an aim to identify filamentous fungal pathogen isolated from HCAI and study its antifungal susceptibility profile. Filamentous fungi isolated from cases of HCAI from intensive care unit (MICU) were included. They were identified by standard mycological techniques and antifungal susceptibility profile was studied. Out of 50 fungal pathogens, spp. were isolated from 21 (42%) cases, whereas 29 (58%) isolates were filamentous fungi. spp. (51.7%) were predominant among filamentous fungal pathogen. (27.6%) was the predominant isolate. Use of broad-spectrum antibiotics followed by neutropenia and presence of indwelling medical devices were common risk factors associated with HCAI due to filamentous fungi. Amphotericin B resistance was observed in 6.9% of isolates whereas 33.3% were resistant to fluconazole. Invasive fungal infection (IFI) though less common is associated with increased morbidity and mortality in patients admitted to ICU. Neutropenia and use of broad spectrum antibiotics are important risk factors for IFI. is the most common filamentous fungus cause of IFI. More emphasis should be given on rapid diagnosis, prompt treatment and strict compliance with infection prevention and control practices.","PeriodicalId":13428,"journal":{"name":"Indian Journal of Microbiology Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87171418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-15DOI: 10.18231/j.ijmr.2022.022
Anjana J C, Fahima Majeed
Herbs are making a comeback, and the herbal renaissance is taking place all over the world. Medicinal plants continue to play an essential role in developing and emerging countries. Considering the chemical and therapeutic elements obtained in natural form from plants and plant extracts, they play an essential role in modern medicine. The present study aims to evaluate the phytochemicals, antimicrobial and anti-inflammatory activity of the aqueous extract of . The phytochemical examination revealed the presence of alkaloids, steroids, coumarins, and glycosides in the root's aqueous extract. The antimicrobial activity against the Gram-negative organisms (that cause urinary and secondary infections) was performed. The aqueous extract showed maximum activity against sp with a zone of inhibition of 28 mm and an almost similar zone size was measured against antibiotics Ciprofloxacin. The anti-inflammatory tests were also performed and the extract exhibited an appreciable presence of anti-inflammatory metabolites. The test extracts inhibited protein (albumin) denaturation in a concentration-dependent manner, according to the current data. Secondary metabolites comprise a vast number of functional moieties that interact to create a broad range of biological functions. Many modern drugs are based on plants and plant-based compounds, and they are currently being used to treat various ailments.
{"title":"In vitro evaluation of biological activities of aqueous extract of S","authors":"Anjana J C, Fahima Majeed","doi":"10.18231/j.ijmr.2022.022","DOIUrl":"https://doi.org/10.18231/j.ijmr.2022.022","url":null,"abstract":"Herbs are making a comeback, and the herbal renaissance is taking place all over the world. Medicinal plants continue to play an essential role in developing and emerging countries. Considering the chemical and therapeutic elements obtained in natural form from plants and plant extracts, they play an essential role in modern medicine. The present study aims to evaluate the phytochemicals, antimicrobial and anti-inflammatory activity of the aqueous extract of . The phytochemical examination revealed the presence of alkaloids, steroids, coumarins, and glycosides in the root's aqueous extract. The antimicrobial activity against the Gram-negative organisms (that cause urinary and secondary infections) was performed. The aqueous extract showed maximum activity against sp with a zone of inhibition of 28 mm and an almost similar zone size was measured against antibiotics Ciprofloxacin. The anti-inflammatory tests were also performed and the extract exhibited an appreciable presence of anti-inflammatory metabolites. The test extracts inhibited protein (albumin) denaturation in a concentration-dependent manner, according to the current data. Secondary metabolites comprise a vast number of functional moieties that interact to create a broad range of biological functions. Many modern drugs are based on plants and plant-based compounds, and they are currently being used to treat various ailments.","PeriodicalId":13428,"journal":{"name":"Indian Journal of Microbiology Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91351189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-15DOI: 10.18231/j.ijmr.2022.014
P. Patel
{"title":"A review of microbiology practice in tertiary care teaching hospital","authors":"P. Patel","doi":"10.18231/j.ijmr.2022.014","DOIUrl":"https://doi.org/10.18231/j.ijmr.2022.014","url":null,"abstract":"","PeriodicalId":13428,"journal":{"name":"Indian Journal of Microbiology Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91520532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-15DOI: 10.18231/j.ijmr.2022.023
Kaina Bhonsle, A. Vyas, H. Vyas, Abhiraj Ramchandani, K. Hemwani
: Urinary tract infection is one of the most common infectious disease found in all population and has become a major health problem. The urinary tract infection also affects pediatric population especially in the age group of 0-5 years. The aim of this study to find out prevalence of UTI in children, its occurrence in different gender and seasons along with identification of causative agent of UTI in children in Ujjain. The study was carried out in SRL laboratory Ujjain center and total 881 suspected patients urine sample were collected and tested by conventional methods for prevalence of significant bacteriuria. It was seen that 550 samples were positive and out of these, positive case 111 belonged to children of 0-5 years of age. Thus, 20.18% positive cases were of children. The percentage of UTI in female children was high (54.0%) while in male children it was low (45.9%) and high number of cases were recorded in rainy season (39.6%), followed by summer and winter seasons which were (34.2%) and (26.1%) respectively. The six major uropathogens present in urine sample were isolated and identified and among them four were gram negative in which . , . , . , . were gram negative while and . and . were gram positive UTI causing bacteria in children. In our study frequency of . was highest (60.3%) while . was present in very low frequency (3.6%) so the prevention of UTI in children should be done by proper care of children by mothers.
{"title":"Prevalence, identification and frequency of uropathogens causing urinary tract infection in children in Ujjain (M.P.)","authors":"Kaina Bhonsle, A. Vyas, H. Vyas, Abhiraj Ramchandani, K. Hemwani","doi":"10.18231/j.ijmr.2022.023","DOIUrl":"https://doi.org/10.18231/j.ijmr.2022.023","url":null,"abstract":": Urinary tract infection is one of the most common infectious disease found in all population and has become a major health problem. The urinary tract infection also affects pediatric population especially in the age group of 0-5 years. The aim of this study to find out prevalence of UTI in children, its occurrence in different gender and seasons along with identification of causative agent of UTI in children in Ujjain. The study was carried out in SRL laboratory Ujjain center and total 881 suspected patients urine sample were collected and tested by conventional methods for prevalence of significant bacteriuria. It was seen that 550 samples were positive and out of these, positive case 111 belonged to children of 0-5 years of age. Thus, 20.18% positive cases were of children. The percentage of UTI in female children was high (54.0%) while in male children it was low (45.9%) and high number of cases were recorded in rainy season (39.6%), followed by summer and winter seasons which were (34.2%) and (26.1%) respectively. The six major uropathogens present in urine sample were isolated and identified and among them four were gram negative in which . , . , . , . were gram negative while and . and . were gram positive UTI causing bacteria in children. In our study frequency of . was highest (60.3%) while . was present in very low frequency (3.6%) so the prevention of UTI in children should be done by proper care of children by mothers.","PeriodicalId":13428,"journal":{"name":"Indian Journal of Microbiology Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80234858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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