Fresh Aloe vera plant leaves were brought from botanical garden and sample was indentied and brought to the laboratory in the Department of Zoology, Patkar-Varde College, Goregaon (W), Mumbai. 50 grams of leaves were then grounded with 50ml of distilled water in sterilized pestle and mortar. The yield will be calculated based on weight of the extract compared to the weight of the pulp of the leaves. Forty eight (48) Sprague- dawley rats (average weight 150 - 250 g) of either sex were used for the experiment. The drugs ETH and PAS drug and Aloe vera juice were given to respective groups daily for 28 days. At the end of study various biochemical parameters were analyzed from serum such as, Bilirubin, ACP, ALP, SGOT (AST), SGPT (ALT), HDL Cholesterol, Total Cholesterol, and TGL. Liver tissues were analyzed for Histopathology. The data was statistically analyzed by one way analysis of variance (ANOVA). The value p< 0.05 considered as signicant. Administration ETH and PAS in Sprague-dawley rats showed hepatotoxicity in test groups which was conrmed by biochemical parameters and histoarchitecture examination of liver. The rats orally administered of Aloe vera juice in combination with the ETH and PAS or independently found to be effective in lowering the elevated levels of bilirubin, ACP, ALP, ALT, AST, HDL to approximate normal level in ETH and PAS treated rats and by elevating the level of TGL. From the histopathalogical study it was also found that ETH and PAS could induce hepatitis through increases in oxidative stress, liver injury, and liver histopathology. Aloe vera juice in acts as hepato-protective agent and recovered the liver to its normal architecture. Thus current research implies the functional potential of Aloe vera juice in hepatotoxicity induced rats.
从植物园采来新鲜的芦荟植物叶，将样本缩，然后带到孟买戈尔甘（西区）帕特卡尔-瓦尔德学院动物学系的实验室。然后将 50 克叶子用 50 毫升蒸馏水在消毒过的杵臼中研磨。产量将根据提取物的重量与叶肉的重量进行比较计算。实验中使用了 48 只 Sprague- dawley 大鼠（平均体重 150 - 250 克），雌雄不限。各组每天分别服用 ETH 和 PAS 药物以及芦荟汁，连续 28 天。研究结束时，分析血清中的各种生化指标，如胆红素、ACP、ALP、SGOT（谷草转氨酶）、SGPT（谷丙转氨酶）、高密度脂蛋白胆固醇、总胆固醇和TGL。数据通过单因素方差分析（ANOVA）进行统计分析。P<0.05为显著cant。在 Sprague-dawley 大鼠体内施用 ETH 和 PAS 后，试验组出现了肝毒性，生化指标和肝脏组织结构检查也证实了这一点rmed by biochemical parameters and histoarchitecture examination of liver.大鼠口服芦荟汁与 ETH 和 PAS 联合或单独服用，可有效降低 ETH 和 PAS 处理大鼠升高的胆红素、ACP、ALP、ALT、AST、HDL 水平，使其接近正常水平，并提高 TGL 水平。组织病理学研究还发现，ETH 和 PAS 可通过增加氧化应激、肝损伤和肝组织病理学而诱发肝炎。芦荟汁具有保护肝脏的作用，可使肝脏恢复正常结构。因此，目前的研究表明芦荟汁对肝毒性诱导的大鼠具有功能潜力。
{"title":"HEPATOPROTECTIVE ROLE OF ALOE VERA JUICE ON ANTITUBERCULOSIS DRUGS ETHIONAMIDE AND PARA AMINO SALICYLIC ACID INDUCED HEPATOTOXICITY IN SPRAGUE-DAWLEY RATS","authors":"Azal Shaikh, Zodape G.V","doi":"10.36106/ijar/2903119","DOIUrl":"https://doi.org/10.36106/ijar/2903119","url":null,"abstract":"Fresh Aloe vera plant leaves were brought from botanical garden and sample was indentied and brought to the\u0000laboratory in the Department of Zoology, Patkar-Varde College, Goregaon (W), Mumbai. 50 grams of leaves were then\u0000grounded with 50ml of distilled water in sterilized pestle and mortar. The yield will be calculated based on weight of the extract compared to the\u0000weight of the pulp of the leaves. Forty eight (48) Sprague- dawley rats (average weight 150 - 250 g) of either sex were used for the experiment.\u0000The drugs ETH and PAS drug and Aloe vera juice were given to respective groups daily for 28 days. At the end of study various biochemical\u0000parameters were analyzed from serum such as, Bilirubin, ACP, ALP, SGOT (AST), SGPT (ALT), HDL Cholesterol, Total Cholesterol, and TGL.\u0000Liver tissues were analyzed for Histopathology. The data was statistically analyzed by one way analysis of variance (ANOVA). The value p<\u00000.05 considered as signicant. Administration ETH and PAS in Sprague-dawley rats showed hepatotoxicity in test groups which was conrmed\u0000by biochemical parameters and histoarchitecture examination of liver. The rats orally administered of Aloe vera juice in combination with the\u0000ETH and PAS or independently found to be effective in lowering the elevated levels of bilirubin, ACP, ALP, ALT, AST, HDL to approximate\u0000normal level in ETH and PAS treated rats and by elevating the level of TGL. From the histopathalogical study it was also found that ETH and\u0000PAS could induce hepatitis through increases in oxidative stress, liver injury, and liver histopathology. Aloe vera juice in acts as hepato-protective\u0000agent and recovered the liver to its normal architecture. Thus current research implies the functional potential of Aloe vera juice in hepatotoxicity\u0000induced rats.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141053632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sebin John Thampan, Madhan Subramaniam, Antonious Maria Selvam, Priya Acka Thomas, Jackin Moses
Unprovoked pulmonary thromboembolism is a very difcult diagnosis owing to the fact that PTE should be suspected based on clinical presentation and conrmed with CT-pulmonary angiogram, but since unprovoked requires no identiable causes are the required criteria makes it even more difcult to start the treatment on early basis. Here is a case series of unprovoked PTE to make aware the prevalence of the same in the ER and to prompt necessary investigations and signs to diagnosis the condition.
{"title":"UNPROVOKED PULMONARY THROMBOEMBOLISM – CASE SERIES","authors":"Sebin John Thampan, Madhan Subramaniam, Antonious Maria Selvam, Priya Acka Thomas, Jackin Moses","doi":"10.36106/ijar/1400463","DOIUrl":"https://doi.org/10.36106/ijar/1400463","url":null,"abstract":"Unprovoked pulmonary thromboembolism is a very difcult diagnosis owing to the fact that PTE should be suspected\u0000based on clinical presentation and conrmed with CT-pulmonary angiogram, but since unprovoked requires no\u0000identiable causes are the required criteria makes it even more difcult to start the treatment on early basis. Here is a case series of unprovoked PTE\u0000to make aware the prevalence of the same in the ER and to prompt necessary investigations and signs to diagnosis the condition.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141057570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Young adulthood can be a tumultuous phase of life where individuals are confronted by complicated psychological, physical, and social transitions. One young adult studying at a women's college presents emotional regulation issues in the classroom. A brief assessment by the counsellor reveals a more critical case with symptoms of severe anxiety, suicidal ideations, and the underlying family trauma of the young adult. This paper illustrates the course of therapeutic treatment for this young adult to resolve the symptoms of anxiety, deep-rooted trauma, and suicidal thoughts. Through a case study approach, the outcomes of the evidence-based techniques utilised by the counsellor- Egan's Skilled Helper Model, Acceptance Commitment Therapy, and the Assessment and Management of Suicide Risk—are shown. This paper illustrates the importance of understanding and tailoring such evidence-based treatment techniques by mental health practitioners, especially for adolescents and young adults with suicide risk.
{"title":"CASE STUDY ON ADDRESSING SUICIDAL IDEATION IN A YOUNG COLLEGE STUDENT UTILIZING THE EGAN MODEL, ACCEPTANCE AND COMMITMENT THERAPY (ACT), AND ASSESSMENT AND MANAGEMENT OF SUICIDE RISK (AMSR)","authors":"Mary Shantha Joseph, K.R. Manjukashika","doi":"10.36106/ijar/5409097","DOIUrl":"https://doi.org/10.36106/ijar/5409097","url":null,"abstract":"Young adulthood can be a tumultuous phase of life where individuals are confronted by complicated psychological,\u0000physical, and social transitions. One young adult studying at a women's college presents emotional regulation issues in the\u0000classroom. A brief assessment by the counsellor reveals a more critical case with symptoms of severe anxiety, suicidal ideations, and the\u0000underlying family trauma of the young adult. This paper illustrates the course of therapeutic treatment for this young adult to resolve the symptoms\u0000of anxiety, deep-rooted trauma, and suicidal thoughts. Through a case study approach, the outcomes of the evidence-based techniques utilised by\u0000the counsellor- Egan's Skilled Helper Model, Acceptance Commitment Therapy, and the Assessment and Management of Suicide Risk—are\u0000shown. This paper illustrates the importance of understanding and tailoring such evidence-based treatment techniques by mental health\u0000practitioners, especially for adolescents and young adults with suicide risk.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141036182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Arthrogryposis Multiplex Congenita is a rare sporadic nonprogressive congenital disorder characterised by multiplejoint contractures and can incorporate muscle weakness and brosis.
{"title":"ARTHROGRYPOSIS MULTIPLES CONGENITA-A CASE REPORT.","authors":"S. I. Ahammad, Shaik Neha Amreen","doi":"10.36106/ijar/4700350","DOIUrl":"https://doi.org/10.36106/ijar/4700350","url":null,"abstract":"Arthrogryposis Multiplex Congenita is a rare sporadic nonprogressive\u0000congenital disorder characterised by multiplejoint contractures and\u0000can incorporate muscle weakness and brosis.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141033872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Osteomas, arising from osteoblasts, are slow-growing benign mesenchymal tumors. While they can appear in any bone, their rarity in the temporal bone and middle ear (0.1% to 1% of benign skull tumors) emphasizes their distinctiveness. Initially asymptomatic, osteomas may become symptomatic with increasing size, commonly causing pain. Their unique prevalence underscores the importance of vigilance, as early stages may lack noticeable symptoms. This insight into osteomas highlights the potential for evolving clinical manifestations, particularly pain, necessitating attention as these benign tumors progress. The Case series: We are describing a case series of 3 unique cases of painless post-aural swelling. Clinical evaluation and a high-resolution CT scan of the temporal bone aided in diagnosing the swelling. Surgical excision was done for all the patients. Post-surgery, histopathological examination conrmed the diagnosis by scrutinizing tissue characteristics, validating the nature of the swelling as an osteoma. This comprehensive approach highlights the importance of accurate diagnosis and subsequent surgical intervention in osteoma cases. Osteomas in Conclusion: the mastoid area of the temporal bone, often presenting as asymptomatic swelling causing cosmetic disgurement, can be effectively treated with total excision, yielding a good prognosis. Despite the lack of ear-related symptoms, vigilance for syndromic associations and extratemporal symptoms is essential. Timely diagnosis and management, especially in cases with potential complications like pain, are crucial. Given the
{"title":"TEMPORAL BONE OSTEOMA – A RARE BENIGN TUMOR : A CASE SERIES","authors":"Rushikesh Harkut, Roshni Mohanty, Ninad Gaikwad, Amruta Tantak","doi":"10.36106/ijar/9601365","DOIUrl":"https://doi.org/10.36106/ijar/9601365","url":null,"abstract":"Background: Osteomas, arising from osteoblasts, are slow-growing benign mesenchymal tumors. While they can\u0000appear in any bone, their rarity in the temporal bone and middle ear (0.1% to 1% of benign skull tumors) emphasizes their\u0000distinctiveness. Initially asymptomatic, osteomas may become symptomatic with increasing size, commonly causing pain. Their unique\u0000prevalence underscores the importance of vigilance, as early stages may lack noticeable symptoms. This insight into osteomas highlights the\u0000potential for evolving clinical manifestations, particularly pain, necessitating attention as these benign tumors progress. The Case series: We are\u0000describing a case series of 3 unique cases of painless post-aural swelling. Clinical evaluation and a high-resolution CT scan of the temporal bone\u0000aided in diagnosing the swelling. Surgical excision was done for all the patients. Post-surgery, histopathological examination conrmed the\u0000diagnosis by scrutinizing tissue characteristics, validating the nature of the swelling as an osteoma. This comprehensive approach highlights the\u0000importance of accurate diagnosis and subsequent surgical intervention in osteoma cases. Osteomas in Conclusion: the mastoid area of the\u0000temporal bone, often presenting as asymptomatic swelling causing cosmetic disgurement, can be effectively treated with total excision,\u0000yielding a good prognosis. Despite the lack of ear-related symptoms, vigilance for syndromic associations and extratemporal symptoms is\u0000essential. Timely diagnosis and management, especially in cases with potential complications like pain, are crucial. Given the","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141050311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aayushi R. Patel, Viral Patel, Harshkumar A. Patel
Context: The Digital Radiography & Magnetic Resonance Imaging scan is a Non-Invasive, Advanced Imaging Technique, which is a used in Clinical Radiology for the Assessment of Various Hip Joint Pathologies. Aims: To correlate the 3D DESS sequence with routine sequence & To evaluate accuracy of 3D DESS sequence in different hip joint pathologies. Settings And Design: Material And Methods: Prospective research study. A total of 60 patients (35 males, 15 females) were selected as a participant. Statistical Analysis: Results: The data were analyzed by using of STATA program 14.2 version. In our 60 patients Research study, There were 21 (42%) Cases of Avascular Necrosis (AVN), 7 (14%) Cases of arthritis, 3 (6%) and 1 (2%) cases were of femoral fracture and acetabular fracture, respectively our ndings showed that MEDIC, 3D-DESS and PDFS were signicantly better than (PD) & STIR sequences in the assessment of all the hip pain pathologies. The 3T MRI is a Modality of Choice for Various Hip Joint Pathologies Conclusion: and more Advantages than Digital Radiograph.
背景：数字射线和磁共振成像扫描是一种非侵入性的先进成像技术，在临床放射学中用于评估各种髋关节病变。目的：将 3D DESS 序列与常规序列进行关联，并评估 3D DESS 序列在不同髋关节病变中的准确性。设置与设计：材料和方法：前瞻性研究。统计分析：统计分析：结果：数据使用 STATA 程序 14.2 版进行分析。ndings showed that MEDIC, 3D-DESS and PDFS were signicantly better than (PD) & STIR sequences in the assessment of all the hip pain pathologies.3T核磁共振成像是治疗各种髋关节病变的首选方式 结论：与数字放射摄影相比，3T核磁共振成像更具优势。
{"title":"A STUDY OF 3T MRI SCAN AND PLAIN RADIOGRAPH IN THE EVALUATION OF PAINFUL HIP JOINT","authors":"Aayushi R. Patel, Viral Patel, Harshkumar A. Patel","doi":"10.36106/ijar/4600294","DOIUrl":"https://doi.org/10.36106/ijar/4600294","url":null,"abstract":"Context: The Digital Radiography & Magnetic Resonance Imaging scan is a Non-Invasive, Advanced Imaging\u0000Technique, which is a used in Clinical Radiology for the Assessment of Various Hip Joint Pathologies. Aims: To correlate\u0000the 3D DESS sequence with routine sequence & To evaluate accuracy of 3D DESS sequence in different hip joint pathologies. Settings And\u0000Design: Material And Methods: Prospective research study. A total of 60 patients (35 males, 15 females) were selected as a participant.\u0000Statistical Analysis: Results: The data were analyzed by using of STATA program 14.2 version. In our 60 patients Research study, There were 21\u0000(42%) Cases of Avascular Necrosis (AVN), 7 (14%) Cases of arthritis, 3 (6%) and 1 (2%) cases were of femoral fracture and acetabular fracture,\u0000respectively our ndings showed that MEDIC, 3D-DESS and PDFS were signicantly better than (PD) & STIR sequences in the assessment of\u0000all the hip pain pathologies. The 3T MRI is a Modality of Choice for Various Hip Joint Pathologies Conclusion: and more Advantages than Digital\u0000Radiograph.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141036910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thashwini Rajandran, Tan Xue Yi, Tan Sue Sian, Fatin Nurfariessa binti Jamal
The need to be able to be ahead of the forecast weather report can be a game changer. Thus, the utilization of a weather station in a farm could have an enormous impact. This study was conducted at Top Fruits Sdn. Bhd. durian farm located in Parit Sulong, Johor, Malaysia. This research spanned partially from January 2023 to December 2023 and involved the utilization of durian trees aged between 5 to 35 years old. The Davis Weather Station has been deployed in the farm to gather continuous weather data. Some notable ndings were found which suggest a direct correlation between an increase in the humidity and a subsequent decrease in the durian harvest yield. The study identied 26.03 °C as the optimum daily average temperature for fruit development, which is the lowest average temperature recorded during the observation period. A high daily average evapotranspiration value, up to 2.68 mm as observed in this publication, favors the durian yield. Pearson's correlation analysis revealed no signicant correlation between rainfall and yield, attributed to the use of sprinkler irrigation when rain was absent. It can be concluded that weather patterns signicantly impact fruit development.
{"title":"THE INFLUENCE OF WEATHER PATTERNS ON DURIAN YIELD IN MALAYSIA","authors":"Thashwini Rajandran, Tan Xue Yi, Tan Sue Sian, Fatin Nurfariessa binti Jamal","doi":"10.36106/ijar/5309823","DOIUrl":"https://doi.org/10.36106/ijar/5309823","url":null,"abstract":"The need to be able to be ahead of the forecast weather report can be a game changer. Thus, the utilization of a weather\u0000station in a farm could have an enormous impact. This study was conducted at Top Fruits Sdn. Bhd. durian farm located in\u0000Parit Sulong, Johor, Malaysia. This research spanned partially from January 2023 to December 2023 and involved the utilization of durian trees\u0000aged between 5 to 35 years old. The Davis Weather Station has been deployed in the farm to gather continuous weather data. Some notable\u0000ndings were found which suggest a direct correlation between an increase in the humidity and a subsequent decrease in the durian harvest yield.\u0000The study identied 26.03 °C as the optimum daily average temperature for fruit development, which is the lowest average temperature recorded\u0000during the observation period. A high daily average evapotranspiration value, up to 2.68 mm as observed in this publication, favors the durian\u0000yield. Pearson's correlation analysis revealed no signicant correlation between rainfall and yield, attributed to the use of sprinkler irrigation when\u0000rain was absent. It can be concluded that weather patterns signicantly impact fruit development.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141046825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alcohol dependence is a psychiatric disorder characterized by an inability to control or reduce alcohol consumption despite experiencing adverse consequences across various life domains. The cyclical pattern of relapse and recovery associated with this disorder perpetuates ongoing challenges for the wives of individuals with alcohol dependence. Repeatedly witnessing their husband's problematic drinking patterns often erodes their sense of hope, making it increasingly difcult for them to maintain emotional stability. Consequently, their frustration tolerance becomes diminished. Moreover, due to the chronic and recurrent nature of alcohol dependence, the wives' coping efforts frequently yield limited success, leading to a profound sense of helplessness. The present study aimed to compare frustration tolerance and helplessness levels in wives of individuals with alcohol dependence and wives of healthy controls. A sample of 100 wives of alcohol dependents was selected through purposive sampling and compared with 100 wives of healthy control subjects on the scales of frustration tolerance and helplessness. The results revealed that wives of alcohol dependents scored signicantly lower on frustration tolerance and higher on helplessness compared to wives of healthy controls.
{"title":"FRUSTRATION TOLERANCE AND HELPLESSNESS IN WIVES OF ALCOHOL DEPENDENTS AND HEALTHY CONTROLS: A COMPARATIVE STUDY","authors":"Pushpendra Kumar Sharma, Shiv Kumar Singh","doi":"10.36106/ijar/3009367","DOIUrl":"https://doi.org/10.36106/ijar/3009367","url":null,"abstract":"Alcohol dependence is a psychiatric disorder characterized by an inability to control or reduce alcohol consumption\u0000despite experiencing adverse consequences across various life domains. The cyclical pattern of relapse and recovery\u0000associated with this disorder perpetuates ongoing challenges for the wives of individuals with alcohol dependence. Repeatedly witnessing their\u0000husband's problematic drinking patterns often erodes their sense of hope, making it increasingly difcult for them to maintain emotional stability.\u0000Consequently, their frustration tolerance becomes diminished. Moreover, due to the chronic and recurrent nature of alcohol dependence, the\u0000wives' coping efforts frequently yield limited success, leading to a profound sense of helplessness. The present study aimed to compare frustration\u0000tolerance and helplessness levels in wives of individuals with alcohol dependence and wives of healthy controls. A sample of 100 wives of alcohol\u0000dependents was selected through purposive sampling and compared with 100 wives of healthy control subjects on the scales of frustration\u0000tolerance and helplessness. The results revealed that wives of alcohol dependents scored signicantly lower on frustration tolerance and higher on\u0000helplessness compared to wives of healthy controls.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141038554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acinetobacter baumannii is one of the most important bacteria in Hospital-acquired infections. Antibiotic resistance in this bacterium leads to many problems in treating patients. This prospective study was conducted on 80 isolates of Acinetobacter baumannii collected from clinical samples in the Microbiology Department, Smt. B. K. Shah Medical Institute and Research Center, Vadodara. The antibiotic resistance pattern was determined by the VITEK 2 automated machine. Out of 80 isolates, the highest rate of sensitivity was seen in Minocycline (50 %). The occurrence of infection was more common in males than females. Isolation of bacterium was more from pus samples than other samples. So the study was conducted to demonstrate the burden of micro-organisms in hospitals and their antibiotic sensitivity pattern.
鲍曼不动杆菌是医院感染中最重要的细菌之一。这种细菌的抗生素耐药性导致了许多治疗病人的问题。这项前瞻性研究针对从瓦多达拉 B. K. 沙阿夫人医学研究所和研究中心微生物部的临床样本中收集的 80 个鲍曼不动杆菌分离株进行。抗生素耐药性模式由 VITEK 2 自动机测定。在 80 个分离株中，米诺环素的敏感率最高（50%）。感染发生率男性高于女性。脓液样本的细菌分离率高于其他样本。因此，开展这项研究的目的是为了说明医院中微生物的负担及其抗生素敏感性模式。
{"title":"ANTIBIOTIC PROFILE OF ACINETOBACTER BAUMANNII IN TERTIARY CARE HOSPITAL, VADODARA, GUJARAT, INDIA","authors":"Bindiya J. Ghedia","doi":"10.36106/ijar/3601469","DOIUrl":"https://doi.org/10.36106/ijar/3601469","url":null,"abstract":"Acinetobacter baumannii is one of the most important bacteria in Hospital-acquired infections. Antibiotic resistance in\u0000this bacterium leads to many problems in treating patients. This prospective study was conducted on 80 isolates of\u0000Acinetobacter baumannii collected from clinical samples in the Microbiology Department, Smt. B. K. Shah Medical Institute and Research\u0000Center, Vadodara. The antibiotic resistance pattern was determined by the VITEK 2 automated machine. Out of 80 isolates, the highest rate of\u0000sensitivity was seen in Minocycline (50 %). The occurrence of infection was more common in males than females. Isolation of bacterium was\u0000more from pus samples than other samples. So the study was conducted to demonstrate the burden of micro-organisms in hospitals and their\u0000antibiotic sensitivity pattern.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141027568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: Enhanced Recovery After Surgery (ERAS) is one of the new concepts in the post operative care in which multidisciplinary approach has implemented for the speedy recovery of the patients. In the present study, ERAS protocol was followed in the C-section patient. In this observational study, 55 patients were recruited, and Materials & Methods: counselling was given to the patients about the ERAS protocol. In the preoperative wards, parameters such as hypertension, glucose, haemoglobin levels were checked. In Obese patient care has taken place for not gaining much weight during the pregnancy period. In the Intra operative ward care was taken in the following sections. Prophylactics antibiotics were given to the patient, in the surgical site antiseptic solution were used to clean the area, IV uids less than 3 litres were given to maintain the normothermia and euvolemia. Warm IVF were given to the patients to prevent hypothermia. To minimize the hypotension induced by spinal anaesthesis, antiemitics and vasopressin were given. After the surgery the patients were reviewed for early oral intake, bowel movements, blood glucose control for wound healing, early mobilisation, and ambulation within rst 8 hours, time for removal of urinary catheter and mother infant bonding. The study showed that more than 75% of the patients showed early mobilisation, ambulation and urinary catheter was removed within 6-12 hours for 76% of the patients. ERAS protocol increased the bonding between the mother and the infant (96%). Thus adapting ERAS protocol in OBG ward will provide improved recovery following surgery.
{"title":"IMPLEMENTATION OF ERAS PROTOCOLS FOLLOWING ELECTIVE CAESAREAN SECTION BY OBSTETRICEAN IN SOUTH INDIA","authors":"Thaarani T, Minthamin Sharon","doi":"10.36106/ijar/7001126","DOIUrl":"https://doi.org/10.36106/ijar/7001126","url":null,"abstract":"Objective: Enhanced Recovery After Surgery (ERAS) is one of the new concepts in the post operative care in which\u0000multidisciplinary approach has implemented for the speedy recovery of the patients. In the present study, ERAS protocol\u0000was followed in the C-section patient. In this observational study, 55 patients were recruited, and Materials & Methods: counselling was given\u0000to the patients about the ERAS protocol. In the preoperative wards, parameters such as hypertension, glucose, haemoglobin levels were checked.\u0000In Obese patient care has taken place for not gaining much weight during the pregnancy period. In the Intra operative ward care was taken in the\u0000following sections. Prophylactics antibiotics were given to the patient, in the surgical site antiseptic solution were used to clean the area, IV uids\u0000less than 3 litres were given to maintain the normothermia and euvolemia. Warm IVF were given to the patients to prevent hypothermia. To\u0000minimize the hypotension induced by spinal anaesthesis, antiemitics and vasopressin were given. After the surgery the patients were reviewed for\u0000early oral intake, bowel movements, blood glucose control for wound healing, early mobilisation, and ambulation within rst 8 hours, time for\u0000removal of urinary catheter and mother infant bonding. The study showed that more than 75% of the patients showed early mobilisation,\u0000ambulation and urinary catheter was removed within 6-12 hours for 76% of the patients. ERAS protocol increased the bonding between the\u0000mother and the infant (96%). Thus adapting ERAS protocol in OBG ward will provide improved recovery following surgery.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141052461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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