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BUPROPION INDUCED DELAYED ONSET URTICARIA: A CASE REPORT 安非他明诱发的迟发性荨麻疹:一份病例报告
Pub Date : 2024-04-01 DOI: 10.36106/ijar/6103235
Sriparna Bhattacharyya, Suresh Chakravarty
Bupropion is an oral antidepressant which acts by inhibiting the reuptake of dopamine and noradrenaline from synapse.Apart from treatment of depressive disorders, it is used off-label for smoking cessation, treatment of attention-decithyperactivity disorder and obesity. Bupropion is generally well-tolerated and has a favorable safety prole. Till date there have only been few casereports of allergic skin reactions associated with bupropion. Apart from being a rare adverse reaction, the unique feature of delayed onset ofallergic reaction may lead to underreporting of the phenomenon. Here we present a case report of a 30 years old male who presented withgeneralized urticaria after twenty-three days of bupropion initiation. This report serves to promote awareness among the clinicians about theassociation of delayed-onset allergic phenomenon with use of Bupropion.
安非他酮是一种口服抗抑郁药,通过抑制突触对多巴胺和去甲肾上腺素的再摄取而发挥作用。除了治疗抑郁障碍外,它还被用于标签外戒烟、治疗注意力,以及肥胖症。安非他酮一般耐受性良好,安全性le。迄今为止,只有少数与安非他酮相关的皮肤过敏反应病例报告。除了是一种罕见的不良反应外,过敏反应延迟发生的独特特征可能会导致对这一现象的报告不足。我们在此报告了一例 30 岁男性在服用安非他酮 23 天后出现全身性荨麻疹的病例。本报告旨在提高临床医生对使用安非他酮会导致迟发性过敏现象的认识。
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引用次数: 0
SOCIAL MEDIA AS A NEW MARKET 社交媒体成为新市场
Pub Date : 2024-04-01 DOI: 10.36106/ijar/7809982
Gargi Agarwal
Progressing digital technology and the immersion of articial intelligence along with the evolving social mediamarketing platforms have led to the enhancement of e-commerce. These techniques have aided businesses in developingstrategies to capture a big audience across geographical borders and also develop probable customers at a reasonable price. Furthermore, thesecurrent technologies promote and publicize the launch of new products, evolve inuential brand leadership strategies, assist in building brandloyalty, anticipate consumers' demands and behavior practices heighten special deals and augment sales by enhancing consumerparticipation.This research paper discusses the evolution of social media marketing platforms and the growth of digital marketing tools. Thestudy highlights the myriad social media marketing channels namely - Facebook, Twitter, Instagram, Pinterest, LinkedIn and YouTube; how theseplatforms operate utilizing their tools to enhance e-commerce and also illustrate a SWOT analysis on social media marketing platforms.Additionally, it analyzes digital marketing tools and online marketing strategies via websites, search engine optimization, email crusades andafliate marketing systems. The research paper concludes with the impact of the advancement of articial intelligence and social mediamarketing behavior on e-commerce.
数字技术的不断进步、艺术cial 智能的融入以及社交媒体营销平台的不断发展,促进了电子商务的发展。这些技术帮助企业制定战略,以合理的价格跨越地理边界抓住大量受众,并发展潜在客户。此外,这些当前的技术还能促进和宣传新产品的推出,发展,制定重要的品牌领导战略,帮助建立品牌忠诚度,预测消费者的需求和行为习惯,通过提高消费者的参与度来提高特别优惠和增加销售额。本研究论文讨论了社交媒体营销平台的发展和数字营销工具的增长。研究强调了无数的社交媒体营销渠道,即 Facebook、Twitter、Instagram、Pinterest、LinkedIn 和 YouTube;这些平台如何利用其工具来加强电子商务,并对社交媒体营销平台进行了 SWOT 分析。此外,研究还分析了数字营销工具和在线营销策略,包括网站、搜索引擎优化、电子邮件营销和其他liate 营销系统。研究论文最后总结了艺术cial 智能和社交媒体营销行为的进步对电子商务的影响。
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引用次数: 0
ENTREPRENEURIAL OPPORTUNITIES: INNOVATION THROUGH HAND STITCHES 创业机会:通过手工缝制实现创新
Pub Date : 2024-04-01 DOI: 10.36106/ijar/5109889
Rinku Agrawal, Madhu Sharan
Hand stitching, a craft that was practiced for constructing garments in ancient times has lost its demand due to the adventof machines. More and more people get engaged in the use of machines rendering hand-stitching obsolete, as it isstrenuous and time-consuming compared to machine stitching. The handcrafted garments do hold a good potential with the use of the righttechniques to assemble and embellish them. This research was taken up to examine the fundamental qualities of hand stitches and their use forcreative clothing seams, surface ornamentation, and decorative elements. Running stitches were explored at length for variation to be used forboth decoration as surface ornamentation and seam construction. The researcher also trained the women without formal education in threesessions so that they could convert the skill for economic independence. The results were so encouraging that self-help groups for women wereestablished where they learned the variety of basic hand stitches for ornamental purposes, which added to the value of the garments. Thereversible elements that can be worn on either side of the garment were designed. As the extension of the work, designs (motifs) were prepared bythe researcher and developed by the trainees, which were prepared to keep in mind the commercial market.
由于机器的出现,手工缝制这种古代用于缝制服装的工艺已经失去了它的需求。与机器缝制相比,手工缝制既费力又耗时,因此越来越多的人开始使用机器缝制,手工缝制也因此被淘汰。如果使用正确的技术进行组装和装饰,手工制作的服装确实具有很大的潜力。这项研究旨在考察手工缝线的基本特性及其在服装接缝、表面装饰和装饰元素方面的应用。研究人员深入探讨了行针在表面装饰和缝合结构中的应用。研究人员还对未受过正规教育的妇女进行了三期培训,使她们能够将这一技能转化为经济独立的能力。结果非常令人鼓舞,妇女们成立了自助小组,学习各种用于装饰的基本手工针法,从而提高了服装的价值。还设计了可穿在衣服两侧的可逆元素。作为工作的延伸,研究人员准备了一些设计(图案),由受训人员根据商业市场的需要进行开发。
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引用次数: 0
CHALLENGES FACED BY THE KITCHEN STAFFS DURING PANDEMICS IN TERTIARY CARE HOSPITAL OF JHARKHAND: A DISCRIPTIVE STUDY 恰尔肯德邦三级医院炊事人员在大流行病期间面临的挑战:一项描述性研究
Pub Date : 2024-04-01 DOI: 10.36106/ijar/5604861
Anju Prabha Kumari, Soma Oraon, Dilip Kumar Paswan
Introduction: Providing appropriate nutrition in the hospital settings is a challenging task due to diverse dietary need ofthe population. (i) to assess different dietary package in the kitchen (ii) to nd out the challeng Objectives: es due toincreasing patient load during pandemic. This was a record based cross sectional study conducted in Methodology: the Central kitchen ofst th Rajendra Institute of Medical Sciences (RIMS), Ranchi for a period of four weeks (1 August to 28 August,2020). Collected Data was entered inMicrosoft Excel Sheet and was analysed using SPSS software version 20. The mean (SD) population tha Result: t was served by the hospitalkitchen 838.86(75.60). The proportion of total patient with respect to total patient was 0.256. The main dietary difference for pandemic patientwas found in terms of high protein content, change in rice quality and use of butter to increase palatability. Due to limited human Conclusion:resource and increasing pandemic patient kitchen staffs were pressurized. The hospital administration must get prepared for unpredictableexponential load due to pandemic or any outbreak.
导言:由于人们的饮食需求各不相同,在医院环境中提供适当的营养是一项具有挑战性的任务。(i) 评估厨房中的不同饮食包 (ii) nd out the challeng Objectives: es due to increasing patient load during pandemic.这是一项基于记录的横断面研究。研究方法:在兰契拉金德拉医学科学研究所(RIMS)中央厨房进行为期四周(2020 年 8 月 1 日至 8 月 28 日)的研究。收集的数据输入 Microsoft Excel 表格,并使用 SPSS 软件版本 20 进行分析。结果:医院服务的平均(标清)人数为 838.86(75.60)人。病人总数占病人总数的比例为 0.256。大流行病患者的膳食差异主要体现在高蛋白含量、米饭质量的改变以及使用黄油增加适口性等方面。由于人力资源有限,加上大流行病患者不断增加,厨房工作人员的压力很大。医院管理部门必须做好准备,应对大流行或任何疫情造成的不可预测的指数级负荷。
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引用次数: 0
PREVALENCE OF HIV AND HEPATITIS VIRUS IN BLOOD DONORS INACHARYA SHRI CHANDRA COLLEGE OF MEDICAL SCIENCES AND HOSPITAL. 印度斯里-钱德拉医学院和医院献血者中艾滋病毒和肝炎的流行情况。
Pub Date : 2024-04-01 DOI: 10.36106/ijar/3903972
Sheeba Parvez, Gazala Shamin, Sana Parvez, Arvind Khajuria
AIM: The present study was undertaken with an aim to investigate the sero prevalence of HIV and hepatitis in blooddonors. Introduction: Blood transfusion constitutes of an important part of patient care, as up to 10% of hospitalizedpatients are transfused. But unsafe blood transfusion have the potential to transmit a diversity of infections to blood recipients. These infectionscould be due to viruses, bacteria, protozoans , and/or prions . Viral agents include human immunodeciency virus (HIV) , Hepatitis B virus (HBV)and Hepatitis C virus (HCV). Material And Methods: The present study was undertaken with an aim to investigate the sero-prevalence of HIVand hepatitis in blood donors. This is a cross sectional study of 200 blood donors in of Acharya shree Chandra college of medical sciences andhospital with age ranging from 18 to 49 years from time period October 2023 to March 2024. Result: Out of 200 donors, only 18 were positivefor hepatitis.( 13 male and 5 female). Also 8 out of 200 were positive for HIV ,out of which 8 were male and 1 was female. It is Conclusion:necessary to estimate the prevalence of infections in the donor community using more sensitive and specic tests than the early tests used.
目的:本研究旨在调查献血者的艾滋病毒和肝炎血清流行率。导言:输血是病人护理的重要组成部分,因为高达 10%的住院病人需要输血。但不安全的输血有可能将多种感染传染给受血者。这些感染可能由病毒、细菌、原生动物和/或朊病毒引起。病毒病原体包括人类免疫缺陷病毒(HIV)、乙型肝炎病毒(HBV)和丙型肝炎病毒(HCV)。材料和方法:本研究旨在调查献血者的艾滋病毒和肝炎血清阳性率。这是一项横断面研究,研究对象是 Acharya shree Chandra 医学院和医院的 200 名献血者,年龄在 18 至 49 岁之间,时间跨度为 2023 年 10 月至 2024 年 3 月。结果:在 200 名献血者中,只有 18 人(13 名男性和 5 名女性)的肝炎抗体呈阳性。此外,200 名捐献者中有 8 人艾滋病毒呈阳性,其中 8 人为男性,1 人为女性。结论:有必要使用比早期测试更灵敏、更具体的测试来估计捐献者群体中的感染率c。
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引用次数: 0
STUDY OF CLINICAL PROFILE OF CHILDREN WITH SICKLE CELL ANEMIA AND EVALUATION OF CARDIAC FUNCTION IN THEM USING 2D ECHOCARDIOGRAPHY 研究镰状细胞性贫血患儿的临床特征并使用 2d 超声心动图评估其心功能
Pub Date : 2024-04-01 DOI: 10.36106/ijar/2303450
Komirisetti Anjaneyulu, N. Madhavi, D. Manikyamba, V. V. Lakshmi
Introduction: Sickle-cell anemia (SCA), a severe form of sickle-cell disease, is a global hemoglobinopathy with asignicant on affected individuals. The disease is characterized by a single point mutation in the β-globin gene, leadingto the synthesis of unstable sickle haemoglobin (HbS). This results in HbS polymerization, oxidative stress, inammation, and endothelialactivation. Despite advancements in treatment strategies, mortality remains high in this population. Cardiac complications, althoughrecognized, are not well-explored. This study aims to investigate the clinical prole of children with SCA and assess cardiac function using 2Dechocardiography.Aims & Objectives:1.To assess clinical prole of children with sickle cell anemia2.Evaluation of cardiac function in them using 2D Echocardiography.Materials and Methods:This prospective observational study was conducted at a Government General Hospital, enrolling children aged 5 to 12 years with SCA.Detaileddemographic information, family history, and clinical data were collected. All enrolled children underwent investigations, including completeblood count (CBC) and 2D Echocardiography was performed by a cardiologist. Data was analysed with appropriate statistical methods. Results:The study included 100 children with SCA, with a mean age of 8.7 years. Clinical presentations revealed a prevalence of vascular occlusion(73%), splenomegaly (14%), infections (7%), and hepatomegaly (6%). Electrocardiographic parameters indicated sinus bradycardia (24%), leftatrial enlargement (19%) and diastolic dysfunction (84%). Mean values of echocardiographic parameters were also reported. Hydroxyureatherapy showed statically signicant improvement in haemoglobin levels, number of blood transfusions, hospital admissions and other clinicalparameters. This study provides valuable insights into the clinical prole especially cardiac abnor Conclusions: malities among children withSCA.All SCA childrens should be routinely screened for cardiac abnormalities and counselled appropriately. The clinical benits ofhydroxyurea therapy highlights the importance of early initiation of this drug in all childrens with SCA.
导言:镰状细胞性贫血(SCA)是镰状细胞病的一种严重形式,是一种全球性的血红蛋白病,对患者的cant。该病的特征是β-球蛋白基因发生单点突变,导致合成不稳定的镰状血红蛋白(HbS)。这导致 HbS 聚合、氧化应激、ammation 和内皮细胞活化。尽管治疗策略有所进步,但这一人群的死亡率仍然很高。心脏并发症虽然已被认识到,但尚未得到很好的研究。本研究旨在调查镰状细胞性贫血患儿的临床原le,并使用二维超声心动图评估心脏功能。Aims & Objectives:1.To assess clinical prole of children with sickle cell anemia2.Evaluation of cardiac function in them using 2D Echocardiography.材料与方法:本前瞻性观察研究在一家政府综合医院进行,共招募了5至12岁的镰状细胞性贫血患儿。收集了详细的人口学信息、家族史和临床数据。所有入组儿童均接受了包括全血细胞计数(CBC)在内的检查,并由心脏病专家进行了二维超声心动图检查。数据采用适当的统计方法进行分析。结果:该研究包括100名患有SCA的儿童,平均年龄为8.7岁。临床表现为血管闭塞(73%)、脾肿大(14%)、感染(7%)和肝肿大(6%)。心电图参数显示窦性心动过缓(24%)、左房扩大(19%)和舒张功能障碍(84%)。此外,还报告了超声心动图参数的平均值。羟基尿疗法在血红蛋白水平、输血次数、入院次数和其他临床参数方面都有显著的改善。这项研究为了解SCA患儿的临床,尤其是心脏异常提供了宝贵的见解。所有SCA患儿都应接受常规的心脏异常筛查,并给予适当的指导。羟基脲治疗的临床良,凸显了对所有SCA患儿尽早使用该药物的重要性。
{"title":"STUDY OF CLINICAL PROFILE OF CHILDREN WITH SICKLE CELL ANEMIA AND EVALUATION OF CARDIAC FUNCTION IN THEM USING 2D ECHOCARDIOGRAPHY","authors":"Komirisetti Anjaneyulu, N. Madhavi, D. Manikyamba, V. V. Lakshmi","doi":"10.36106/ijar/2303450","DOIUrl":"https://doi.org/10.36106/ijar/2303450","url":null,"abstract":"Introduction: Sickle-cell anemia (SCA), a severe form of sickle-cell disease, is a global hemoglobinopathy with a\u0000signicant on affected individuals. The disease is characterized by a single point mutation in the β-globin gene, leading\u0000to the synthesis of unstable sickle haemoglobin (HbS). This results in HbS polymerization, oxidative stress, inammation, and endothelial\u0000activation. Despite advancements in treatment strategies, mortality remains high in this population. Cardiac complications, although\u0000recognized, are not well-explored. This study aims to investigate the clinical prole of children with SCA and assess cardiac function using 2D\u0000echocardiography.\u0000Aims & Objectives:\u00001.To assess clinical prole of children with sickle cell anemia\u00002.Evaluation of cardiac function in them using 2D Echocardiography.\u0000Materials and Methods:\u0000This prospective observational study was conducted at a Government General Hospital, enrolling children aged 5 to 12 years with SCA.Detailed\u0000demographic information, family history, and clinical data were collected. All enrolled children underwent investigations, including complete\u0000blood count (CBC) and 2D Echocardiography was performed by a cardiologist. Data was analysed with appropriate statistical methods. Results:\u0000The study included 100 children with SCA, with a mean age of 8.7 years. Clinical presentations revealed a prevalence of vascular occlusion\u0000(73%), splenomegaly (14%), infections (7%), and hepatomegaly (6%). Electrocardiographic parameters indicated sinus bradycardia (24%), left\u0000atrial enlargement (19%) and diastolic dysfunction (84%). Mean values of echocardiographic parameters were also reported. Hydroxyurea\u0000therapy showed statically signicant improvement in haemoglobin levels, number of blood transfusions, hospital admissions and other clinical\u0000parameters. This study provides valuable insights into the clinical prole especially cardiac abnor Conclusions: malities among children with\u0000SCA.All SCA childrens should be routinely screened for cardiac abnormalities and counselled appropriately. The clinical benits of\u0000hydroxyurea therapy highlights the importance of early initiation of this drug in all childrens with SCA.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140794748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ANAESTHETIC MANAGEMENT OF A PATIENT WITH RHEUMATIC VALVULAR HEART DISEASE POSTED FOR FIXATION OF ACETABULUM FRACTURE 对一名因髋臼骨折固定而住院的风湿性瓣膜性心脏病患者的麻醉管理
Pub Date : 2024-04-01 DOI: 10.36106/ijar/6201529
Surhud Vijaysingh Patil, Vasanti Sasturkar (Kelkar)
Patients with rheumatic heart disease (RHD) undergoing non-cardiac surgeries present a challenge for anesthesiologists.This case report discusses the anesthetic management of a 56-year-old female with severe mitral stenosis, posted foracetabulum fracture xation. The patient's history revealed RHD with severe mitral stenosis, mild mitral regurgitation, and severe pulmonaryhypertension.Considering the risks associated with neuraxial anesthesia in mitral stenosis, general anesthesia (GA) with a Pericapsular Nerve Group (PENG)block was chosen. The patient was carefully premedicated, induced with appropriate drugs, and monitored intraoperatively. The PENG block,performed under ultrasound guidance, aimed to reduce hip pain without causing motor blockade.The patient remained hemodynamically stable throughout the surgery, and postoperatively, the combination of GA with PENG block providedeffective pain control, reducing the need for opioids. This approach contributed to an early recovery, emphasizing the importance of tailoredanesthesia strategies for valvular heart disease patients undergoing non-cardiac surgeries.
接受非心脏手术的风湿性心脏病(RHD)患者给麻醉医生带来了挑战。本病例报告讨论了对一名患有严重二尖瓣狭窄、髋臼骨折的56岁女性的麻醉管理xation。考虑到二尖瓣狭窄患者神经麻醉的相关风险,我们选择了全身麻醉(GA)和包膜神经组(PENG)阻滞。患者经过仔细的术前准备、适当的药物诱导和术中监测。在超声引导下进行的PENG阻滞旨在减轻髋部疼痛,同时不引起运动阻滞。患者在整个手术过程中血流动力学保持稳定,术后,GA与PENG阻滞的结合提供了有效的疼痛控制,减少了对阿片类药物的需求。这种方法有助于患者早日康复,强调了为接受非心脏手术的瓣膜性心脏病患者量身定制麻醉策略的重要性。
{"title":"ANAESTHETIC MANAGEMENT OF A PATIENT WITH RHEUMATIC VALVULAR HEART DISEASE POSTED FOR FIXATION OF ACETABULUM FRACTURE","authors":"Surhud Vijaysingh Patil, Vasanti Sasturkar (Kelkar)","doi":"10.36106/ijar/6201529","DOIUrl":"https://doi.org/10.36106/ijar/6201529","url":null,"abstract":"Patients with rheumatic heart disease (RHD) undergoing non-cardiac surgeries present a challenge for anesthesiologists.\u0000This case report discusses the anesthetic management of a 56-year-old female with severe mitral stenosis, posted for\u0000acetabulum fracture xation. The patient's history revealed RHD with severe mitral stenosis, mild mitral regurgitation, and severe pulmonary\u0000hypertension.\u0000Considering the risks associated with neuraxial anesthesia in mitral stenosis, general anesthesia (GA) with a Pericapsular Nerve Group (PENG)\u0000block was chosen. The patient was carefully premedicated, induced with appropriate drugs, and monitored intraoperatively. The PENG block,\u0000performed under ultrasound guidance, aimed to reduce hip pain without causing motor blockade.\u0000The patient remained hemodynamically stable throughout the surgery, and postoperatively, the combination of GA with PENG block provided\u0000effective pain control, reducing the need for opioids. This approach contributed to an early recovery, emphasizing the importance of tailored\u0000anesthesia strategies for valvular heart disease patients undergoing non-cardiac surgeries.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140783529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A DESCRIPTIVE STUDY TO ASSESS THE LEVEL OF SELF-ESTEEM AMONG B.Sc AND GNM 1ST YEAR NURSING STUDENTS OF NEMCARE INSTITUTE OF NURSING SCIENCES,NEMCARE FOUNDATION, MIRZA, KAMRUP ®, ASSAM. 对阿萨姆邦米尔扎卡姆鲁普护理学院护理学本科和硕士一年级学生自我评价水平的描述性研究。
Pub Date : 2024-04-01 DOI: 10.36106/ijar/2502485
Siddhartha Lodh, Priyanka Porh, Nurija Parbin, Sadhana Baishya
Background of the study: Self-esteem is the inner state of a person's abilities, capacities, capabilities & aptitude, to feelworthy, respected & valued. This should promote condence and necessary parameter of the development of one'spersonal & professional identity. To assess the level of self-esteem among 1st year nursing student Aim: Method: s. Using quantitative researchapproach and descriptive research design. 110 samples were collected through convenient sampling method. result show that majority of Result:nursing students i.e.102 (92.7%) have normal self-esteem level, 1 (0.91%) students have high self-esteem level, and 7 (6.36%) students have lowself-esteem level. There was signicant association of level of self-esteem with demographic variables i.e. age, caste, religion, type of family andadaptation of the course. The study concluded that majority of participants have normal self-esteem Conclusion: and there is signicantassociation between level of self-esteem and demographic variables i.e. age, caste, religion, type of family and adaptation of the course.
研究背景:自尊是一个人对自己的能力、才干、才干和才干感到值得、受尊重和受重视的内心状态。这应促进自信,是个人和职业身份发展的必要参数dence。采用定量研究方法和描述性研究设计。结果表明,大多数护理专业一年级学生,即 102 人(92.7%)的自尊水平正常,1 人(0.91%)的自尊水平较高,7 人(6.36%)的自尊水平较低。自尊水平与人口统计学变量(即年龄、种姓、宗教信仰、家庭类型和课程适应性)存在显著。研究得出结论,大多数参与者的自尊心正常 结论:自尊心水平与人口统计学变量(即年龄、种姓、宗教信仰、家庭类型和课程适应性)之间存在显著。
{"title":"A DESCRIPTIVE STUDY TO ASSESS THE LEVEL OF SELF-ESTEEM AMONG B.Sc AND GNM 1ST YEAR NURSING STUDENTS OF NEMCARE INSTITUTE OF NURSING SCIENCES,NEMCARE FOUNDATION, MIRZA, KAMRUP ®, ASSAM.","authors":"Siddhartha Lodh, Priyanka Porh, Nurija Parbin, Sadhana Baishya","doi":"10.36106/ijar/2502485","DOIUrl":"https://doi.org/10.36106/ijar/2502485","url":null,"abstract":"Background of the study: Self-esteem is the inner state of a person's abilities, capacities, capabilities & aptitude, to feel\u0000worthy, respected & valued. This should promote condence and necessary parameter of the development of one's\u0000personal & professional identity. To assess the level of self-esteem among 1st year nursing student Aim: Method: s. Using quantitative research\u0000approach and descriptive research design. 110 samples were collected through convenient sampling method. result show that majority of Result:\u0000nursing students i.e.102 (92.7%) have normal self-esteem level, 1 (0.91%) students have high self-esteem level, and 7 (6.36%) students have low\u0000self-esteem level. There was signicant association of level of self-esteem with demographic variables i.e. age, caste, religion, type of family and\u0000adaptation of the course. The study concluded that majority of participants have normal self-esteem Conclusion: and there is signicant\u0000association between level of self-esteem and demographic variables i.e. age, caste, religion, type of family and adaptation of the course.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140795918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CORRELATION OF PROPHYLACTIC AND THERAPEUTIC DOSE OF LMW HEPARIN WITH RESPECT TO OUTCOME IN CRITICALLY ILL PATIENTS OF COVID-19. Covid-19危重病人肝素的预防和治疗剂量与预后的相关性。
Pub Date : 2024-04-01 DOI: 10.36106/ijar/6003165
Rameshwar Alane, Venkatesh Khadke, Saleem Tamboli, P. Jadhav, Rahul Parsode
Introduction- Recently, a novel coronavirus (2019-nCoV), ofcially known as severe acute respiratory syndromecoronavirus 2 (SARS-CoV-2), caused a severe pandemic infection worldwide with considerable morbidity andmortality. A relatively high mortality of severe coronavirus disease 2019 (COVID-19) is worrying, and the application of heparin in COVID-19has been recommended by some expert consensus because of the risk of disseminated intravascular coagulation and venous thromboembolism.However, its efcacy remains to be validated.We aim to Correlate the association between prophylactic and therapeutic dosages of lowmolecular weight heparin (LMWH) on mortality and other morbidity outcomes in critically ill patients of COVID-19 . Consecutive Methodspatients admitted to Dr. S. C.GMC Medical college and hospital Nanded with laboratory-conrmed COVID-19 were included in thisretrospective observational study. The diagnosis of COVID-19 was established according to World Health Organization interim guidance andconrmed by RNA detection of the SARS-CoV-2 in the microbiology laboratory of the hospital. Outcomes between COVID-19 patients treatedwith standard prophylactic LMWH enoxaparin dosage (subcutaneous enoxaparin 40–60 mg daily) or Therapeutic LMWH enoxaparin dosage(subcutaneous enoxaparin 40–60 mg twice daily) for 7 days were correlated. Out of 100 patients 50 re Results - ccived P-LMWH & 50 reccivedT-LMWH among that 12 % patients expired in prophylactic group & 22% in therapeutic group. It was observed that the levels of D-dimerbefore & after of P-LMWH group were (D-dimer: 2.63±1.77, 0.63±1.19) and those of T-LMWH group were(D-dimer: 3.14 ± 2.15, 1.07 ±1.56 ).the length of hospital stay was (11 ± 2.21) days in the P-LMWH group and (11 ± 3.99 ) Days in the T-LMWH group. Simillarly the saturationlevel of oxygen ware (SPO2 98% ) in P-LMWH group & (SPO2 97%) in T-LMWH group. 26% patients shows adverse effects to P-LMWHgroup & 32% patients to T-LMWH group. Study demonstrates that if you start earlier prophylactic LMW Conclusion- heparin to critically illpatients of covid 19 with raised D-dimer level the level of d-dimer will not further increased and comes down to normal value. Simillarly patientsrecover earlier and reduces hospital stay of patients with improvement in oxygen saturation.
导言--最近,一种新型冠状病毒(2019-nCoV),cially known as severe acute respiratory syndromecoronavirus 2 (SARS-CoV-2),在全球范围内引起了严重的大流行感染,造成了相当高的发病率和死亡率。2019 年严重冠状病毒病(COVID-19)相对较高的死亡率令人担忧,由于存在播散性血管内凝血和静脉血栓栓塞的风险,一些专家一致建议在 COVID-19 中应用肝素。我们的目的是研究低分子量肝素(LMWH)的预防和治疗剂量与 COVID-19 重症患者死亡率和其他发病率之间的关系。S.C.GMC医学院和南德医院收治的化验结果为COVID-19的连续患者被纳入这项回顾性观察研究。COVID-19的诊断是根据世界卫生组织的临时指南确定的,并通过医院微生物实验室检测到的SARS-CoV-2的RNA进行conrmed。对使用标准预防性 LMWH 依诺肝素剂量(皮下注射依诺肝素,每天 40-60 毫克)或治疗性 LMWH 依诺肝素剂量(皮下注射依诺肝素,每天两次,每次 40-60 毫克)治疗 7 天的 COVID-19 患者的疗效进行了比较。在 100 名患者中,50 人接受了 P-LMWH 治疗,50 人接受了 T-LMWH 治疗,其中 12% 的患者在预防组死亡,22% 的患者在治疗组死亡。据观察,P-LMWH 组前后的 D-二聚体水平分别为(D-二聚体:2.63±1.77,0.63±1.19),T-LMWH 组的 D-二聚体水平分别为(D-二聚体:3.14±2.15,1.07±1.56),P-LMWH 组的住院时间为(11±2.21)天,T-LMWH 组为(11±3.99)天。同样,P-LMWH 组的血氧饱和度为(SPO2 98%),T-LMWH 组为(SPO2 97%)。P-LMWH组有26%的患者出现不良反应,T-LMWH组有32%的患者出现不良反应。研究表明,如果对 D-二聚体水平升高的 covid 19 重症患者及早使用预防性 LMW 结论-肝素,D-二聚体水平就不会进一步升高,并会降至正常值。同样,患者也能更早康复,缩短住院时间,改善血氧饱和度。
{"title":"CORRELATION OF PROPHYLACTIC AND THERAPEUTIC DOSE OF LMW HEPARIN WITH RESPECT TO OUTCOME IN CRITICALLY ILL PATIENTS OF COVID-19.","authors":"Rameshwar Alane, Venkatesh Khadke, Saleem Tamboli, P. Jadhav, Rahul Parsode","doi":"10.36106/ijar/6003165","DOIUrl":"https://doi.org/10.36106/ijar/6003165","url":null,"abstract":"Introduction- Recently, a novel coronavirus (2019-nCoV), ofcially known as severe acute respiratory syndrome\u0000coronavirus 2 (SARS-CoV-2), caused a severe pandemic infection worldwide with considerable morbidity and\u0000mortality. A relatively high mortality of severe coronavirus disease 2019 (COVID-19) is worrying, and the application of heparin in COVID-19\u0000has been recommended by some expert consensus because of the risk of disseminated intravascular coagulation and venous thromboembolism.\u0000However, its efcacy remains to be validated.We aim to Correlate the association between prophylactic and therapeutic dosages of low\u0000molecular weight heparin (LMWH) on mortality and other morbidity outcomes in critically ill patients of COVID-19 . Consecutive Methodspatients admitted to Dr. S. C.GMC Medical college and hospital Nanded with laboratory-conrmed COVID-19 were included in this\u0000retrospective observational study. The diagnosis of COVID-19 was established according to World Health Organization interim guidance and\u0000conrmed by RNA detection of the SARS-CoV-2 in the microbiology laboratory of the hospital. Outcomes between COVID-19 patients treated\u0000with standard prophylactic LMWH enoxaparin dosage (subcutaneous enoxaparin 40–60 mg daily) or Therapeutic LMWH enoxaparin dosage\u0000(subcutaneous enoxaparin 40–60 mg twice daily) for 7 days were correlated. Out of 100 patients 50 re Results - ccived P-LMWH & 50 reccived\u0000T-LMWH among that 12 % patients expired in prophylactic group & 22% in therapeutic group. It was observed that the levels of D-dimer\u0000before & after of P-LMWH group were (D-dimer: 2.63±1.77, 0.63±1.19) and those of T-LMWH group were(D-dimer: 3.14 ± 2.15, 1.07 ±1.56 ).\u0000the length of hospital stay was (11 ± 2.21) days in the P-LMWH group and (11 ± 3.99 ) Days in the T-LMWH group. Simillarly the saturation\u0000level of oxygen ware (SPO2 98% ) in P-LMWH group & (SPO2 97%) in T-LMWH group. 26% patients shows adverse effects to P-LMWH\u0000group & 32% patients to T-LMWH group. Study demonstrates that if you start earlier prophylactic LMW Conclusion- heparin to critically ill\u0000patients of covid 19 with raised D-dimer level the level of d-dimer will not further increased and comes down to normal value. Simillarly patients\u0000recover earlier and reduces hospital stay of patients with improvement in oxygen saturation.","PeriodicalId":13502,"journal":{"name":"Indian journal of applied research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140796938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IMPACT OF PANDEMIC ON SLEEP DISTURBANCE AMONG ADOLESCENTS AND YOUNG ADULTS 大流行病对青少年睡眠障碍的影响
Pub Date : 2024-04-01 DOI: 10.36106/ijar/2401363
V. S. Devi, S. A. Begum, A. S. Rani, G. M. Latha
The COVID19 pandemic has led to signicant changes in daily routines and lifestyle worldwide and mental health issueshave emerged consequently. The aim to assess the presence of sleep disturbances before and after the pandemic in theadolescents and young adults age groups in the general population. Methods: Survey data were collected by using snowball sampling method inthe general populations. Participants included 234 in total, in those 100 subjects were adolescents(13-24years) and 130 subjects were belongingto age group of 25-44years. Cross sectional study was proceeded and the prevalence rate of various components of sleep pattern was assessedusing the Pittsburgh sleeping quality index questionaries. Interpretation: Although, the quality of sleep doesn't show variation amongadolescent, but the other domains of sleep pattern are changed aggressively. The % sleep latency was increased which indicates poor sleeppattern. Sleeping duration are also greatly decreased, which leads to fall in the efciency of the sleep. Moderate sleep disturbances were greatlyaffected. Overall good sleeper prevalence rate was drastically falls among adolescents after the pandemic period. The sleep quality and sleeplatency among young adults of bad sleepers was improved after the pandemic. while the other components of the PSQI of sleep was drasticallyaffected. The duration of sleep was greatly affected. The efciency among good sleepers was highly affected. The prevalence rate was doubledon severe sleep disturbance in young adults. Mild daytime dysfunction persistently high in both periods. Overall moderate severely sleepdisturbers rate was increased. Lifestyle changes and sleep disturbances have been occurring in hand Conclusion: and hand, it's needed toevaluate the psychological aetiology of sleep disorders because sleeping is the most important indicator of mental wellbeing and treat the patientsaccordingly to prevent the mental illness among adolescents and young adults.
COVID19大流行导致全球范围内的日常生活方式和生活方式发生了重大,心理健康问题也随之出现。本研究旨在评估大流行前后普通人群中青少年和年轻成年人年龄组的睡眠障碍情况。调查方法采用滚雪球式抽样方法在普通人群中收集调查数据。参与者共 234 人,其中 100 人为青少年(13-24 岁),130 人为 25-44 岁年龄组。调查采用横断面研究方法,并通过匹兹堡睡眠质量指数问卷评估了睡眠模式各组成部分的患病率。解读:虽然青少年的睡眠质量没有变化,但睡眠模式的其他方面却发生了积极变化。睡眠潜伏期百分比增加,表明睡眠模式不佳。睡眠持续时间也大大缩短,导致睡眠ciency 下降。中度睡眠障碍受到很大影响。大流行过后,青少年的总体良好睡眠率急剧下降。大流行后,不良睡眠者中的青壮年的睡眠质量和睡眠时长有所改善,但睡眠 PSQI 的其他组成部分则受到严重影响。睡眠持续时间受到很大影响。睡眠质量好的人的睡眠效率(efciency)受到很大影响。青壮年中严重睡眠障碍的发生率增加了一倍。轻度日间功能障碍在这两个时期都居高不下。总体而言,中度严重睡眠障碍者的比例有所上升。结论:生活方式的改变与睡眠障碍同时发生,需要评估睡眠障碍的心理病因,因为睡眠是精神健康的最重要指标,并根据患者的情况进行治疗,以预防青少年和青壮年的精神疾病。
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Indian journal of applied research
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