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Internet use among persons with common mental disorders: Comment 常见精神障碍患者使用互联网的情况:评论
Pub Date : 2024-02-16 DOI: 10.4103/ipj.ipj_318_23
H. Daungsupawong, V. Wiwanitkit
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引用次数: 0
A Study of the association of neurocognition with relapse and quality of life in patients of alcohol dependence 神经认知与酒精依赖症患者复发和生活质量的关系研究
Pub Date : 2024-02-16 DOI: 10.4103/ipj.ipj_158_23
Daisy Rure, Makhan Shakya, Akanksha Singhal, Akshat Varma, Nimisha Mishra, Umesh Pathak
Alcohol is a widely consumed substance associated with around 5.6% of all causes of death. Alcohol use disorder (AUD) is a chronic relapsing and remitting illness and has been known to be associated with impaired executive functions, processing speed, memory, attention, and fluency. It is also associated with impaired quality of life (QoL), which in turn can affect overall prognosis. To assess neurocognition in patients with alcohol dependence and correlate it with QoL and relapse. This study was a prospective, longitudinal study of sixty alcohol dependence patients from January 2020 to June 2021 after appropriate ethical approval. Participants were assessed for baseline alcohol dependence, neurocognition (focused, sustained and divided attention; processing speed; verbal and category fluency; working memory; response inhibition; verbal comprehension; verbal learning and memory; visuospatial construction; visual learning and memory) and QoL using Alcohol Use Disorders Identification Test (AUDIT), National Institute of Mental Health and Neurosciences (NIMHANS) battery for neurocognition and WHO-BREF (WHO-Quality of Life-short-form scale) World Health Organization-scale, respectively. A follow-up was conducted in three months to assess relapse in the patients. Statistical analysis was conducted by International Business Machines Statistical Package for the Social Sciences (IBM SPSS) v16. Mean age of the study participants was 41.3 ± 5.03 years, mean age of onset of alcohol use was 20.88 ± 4.27 years, mean duration of alcohol use of 16.6 ± 7.92 years, and average 14.55 ± 4.86 drinks per day. The mean AUDIT score of the study population was 25.21 ± 7.18. There was significant positive correlation between duration of use and CTT-2; 37 out of 57 participants relapsed to alcohol (three participants had died in follow-up) with mean 37.48 ± 23.27 days of relapse, mean 3.32 ± 1.2 drinking days per week, and mean 6 ± 1.2 drinks per drinking day. There was negative and positive correlation between neurocognition and relapse and between neurocognition and QoL. Alcohol use also resulted in impaired cognitive function of the study participants. There was also significant difference in score for neurocognition test between relapse and abstinent group. The significant correlation between neurocognition and QoL as well as neurocognition and relapse proves the deleterious effect of alcohol in every aspect of life.
酒精是一种广泛使用的物质,在所有死亡原因中约有 5.6% 与之相关。酒精使用障碍(AUD)是一种慢性复发和缓解性疾病,已知与执行功能、处理速度、记忆力、注意力和流畅性受损有关。它还与生活质量(QoL)受损有关,而这反过来又会影响整体预后。 目的:评估酒精依赖症患者的神经认知,并将其与生活质量和复发相关联。 本研究是一项前瞻性纵向研究,在获得适当的伦理批准后,于 2020 年 1 月至 2021 年 6 月对 60 名酒精依赖症患者进行了研究。研究人员分别使用酒精使用障碍鉴定测试(AUDIT)、美国国家精神卫生和神经科学研究所(NIMHANS)神经认知测试和世界卫生组织生活质量短式量表(WHO-BREF)对参与者进行了基线酒精依赖、神经认知(集中、持续和分散注意;处理速度;言语和类别流畅性;工作记忆;反应抑制;言语理解;言语学习和记忆;视觉空间构造;视觉学习和记忆)和生活质量评估。三个月后进行随访,以评估患者的复发情况。统计分析采用国际商业机器公司的社会科学统计软件包(IBM SPSS)v16。 研究参与者的平均年龄为(41.3 ± 5.03)岁,开始饮酒的平均年龄为(20.88 ± 4.27)岁,平均饮酒时间为(16.6 ± 7.92)年,平均每天饮酒量为(14.55 ± 4.86)杯。研究人群的平均 AUDIT 得分为 25.21 ± 7.18。酗酒时间与 CTT-2 呈明显正相关;57 名参与者中有 37 人复发(3 人在随访中死亡),平均复发天数为(37.48 ± 23.27)天,平均每周饮酒天数为(3.32 ± 1.2)天,平均每天饮酒天数为(6 ± 1.2)天。神经认知与复发之间以及神经认知与 QoL 之间存在负相关和正相关。 饮酒还导致研究参与者的认知功能受损。复发组和戒酒组的神经认知测试得分也存在明显差异。神经认知与 QoL 以及神经认知与复发之间的显着相关性证明了酒精对生活各个方面的有害影响。
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引用次数: 0
Camptocormia: A clinical enigma 凸眼症:临床之谜
Pub Date : 2024-02-16 DOI: 10.4103/ipj.ipj_297_23
T. Ali, Suprakash Chaudhury, Bhushan Chaudhari, D. Saldanha
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引用次数: 0
Hypoglycaemia in lithium toxicity: A rare clinical entity presenting with a diagnostic dilemma 锂中毒的低血糖症:罕见的临床表现与诊断难题
Pub Date : 2024-02-16 DOI: 10.4103/ipj.ipj_164_23
Shilpa Mandal, J. Prakash, Prateek Yadav, Mohit Agrawal
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引用次数: 0
Pagophagia: A case series 吞咽困难:病例系列
Pub Date : 2024-02-16 DOI: 10.4103/ipj.ipj_178_23
Santosh Kumar, Suchita Jain, Satish Kumar Sinha, Suprakash Chaudhury
Pica, in the form of ingestion of various non-food items like clay, chalks, etc., is commonly reported in Indian settings, but its other variant, pagophagia (ice eating), gets attention rarely. This case series is about three female patients who presented in psychiatry outpatient clinics with various mental health issues and ice eating habits. A diagnosis of iron deficiency anemia was common among all three cases, and they were managed with oral iron supplementation along with appropriate psychiatric treatments. Pagophagia is an important clinical presentation to be looked for in the changing Indian society.
在印度,以摄入粘土、粉笔等各种非食物形式出现的 "食冰症 "很常见,但它的另一种变体--"食冰症"(pagophagia)却很少受到关注。本系列病例涉及三名女性患者,她们因各种精神健康问题和食冰习惯来到精神科门诊就诊。这三个病例都被诊断为缺铁性贫血,她们在接受适当的精神治疗的同时,还接受了口服铁补充剂的治疗。在不断变化的印度社会中,食冰症是一个值得注意的重要临床表现。
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引用次数: 0
Eating behaviours, social media usage, and its association: A cross-sectional study in Indian medical undergraduates 饮食行为、社交媒体使用及其关联:印度医学本科生的横断面研究
Pub Date : 2024-02-16 DOI: 10.4103/ipj.ipj_298_23
N. Sawant, Shermeen Rajesh More, Shreyansh Dinesh Singh, Ansh Sanjay Agrawal, Ananya Chauhan
Despite increasing incidence, there is little data on abnormal eating behaviours or disorders in Indian youth, especially medical students. Additionally, little literature exists measuring the association of social media use with abnormal eating behaviours. To assess the prevalence of abnormal eating behaviours amongst medical students, social media usage, and any association of social media usage with eating behaviours. An online cross-sectional questionnaire-based study was conducted with 272 participants at a medical college, and two scales: the Three-Factor Eating Questionnaire-Revised 21items (TFEQ-R21) and the Scale of Effects of social media on Eating Behaviour (SESMEB) were used. 22% of the participants reported abnormal eating behaviours. A significant difference in the effect of social media on eating behaviour according to the year of study [f = 3.08, P = 0.02] was seen with the final years having the lowest and the first years having the highest SESMEB scores. Students using more than 4 social media platforms had a higher SESMEB score [t = -2.02, P < 0.04]. A positive correlation was seen between TFEQ domains such as uncontrolled eating [r = 0.38, P = 0.01], emotional eating [r = 0.30, P = 0.01], and TFEQ total score [r = 0.40, P = 0.01] with SESMEB scores. This study finds a significant correlation between increased social media usage and developing abnormal eating behaviours in medical students. It highlights the need for the creation of policies regulating social media use with eating behaviours in mind.
尽管印度年轻人,尤其是医科学生的异常饮食行为或失调的发生率越来越高,但有关这方面的数据却很少。此外,关于社交媒体的使用与异常饮食行为之间关系的文献也很少。 目的:评估医学生中异常饮食行为的发生率、社交媒体使用情况以及社交媒体使用与饮食行为之间的关联。 研究采用了两个量表:饮食三因素问卷-修订版 21 项(TFEQ-R21)和社交媒体对饮食行为的影响量表(SESMEB)。 22%的参与者报告了异常饮食行为。在社交媒体对饮食行为的影响方面,不同年级的学生有明显差异[f = 3.08, P = 0.02],最后一年的学生得分最低,而第一年的学生得分最高。使用 4 个以上社交媒体平台的学生的 SESMEB 分数较高 [t = -2.02,P < 0.04]。TFEQ的失控进食[r = 0.38, P = 0.01]、情绪化进食[r = 0.30, P = 0.01]和TFEQ总分[r = 0.40, P = 0.01]与SESMEB得分呈正相关。 本研究发现,医学生社交媒体使用量的增加与饮食行为异常之间存在明显的相关性。它强调了在制定社交媒体使用政策时考虑到饮食行为的必要性。
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引用次数: 0
Violence against women during pregnancy and its dimensions in COVID-19 pandemic: A systematic review and meta-analysis COVID-19大流行病中的孕期暴力侵害妇女行为及其影响因素:系统回顾和荟萃分析
Pub Date : 2024-02-16 DOI: 10.4103/ipj.ipj_167_23
S. Aghababaei, Zahra Masoumi, Reza Tahmasebi, E. Jenabi, Zahra Toosi, S. Ghelichkhani
This systematic review and meta-analysis investigated the prevalence of violence against pregnant women during COVID-19 pandemic based on the available evidence. Medline, Scopus, Web of Science, and Google Scholar were searched. All published observational articles from December 2019 to December 2022 were assessed by two independent authors using the “violence, pregnancy, COVID-19” keywords. The quality appraisal of primary studies conducted using the Newcastle - Ottawa Quality Assessment Scale checklist and 10 eligible articles were included in this review. After reviewing the articles, the prevalence of violence among pregnant women during the COVID-19 pandemic was estimated to be 23% [95% confidence interval (CI) =18 to 29%] using the random effect model. Of them, 59% (95% CI = 13 to 105%) was attributed to verbal-behavioral violence, 30% (95% CI = 17 to 42%) emotional violence, 14% (95% CI = 8 to 20%) sexual violence, and 11% physical violence (95% CI = 6 to 17%). The results indicated that the violence prevalence among pregnant women was not different during and before the start of the COVID-19 pandemic. However, the behavioral-verbal, emotional, physical, and sexual violence were the most common forms of violence.
本系统综述和荟萃分析以现有证据为基础,调查了 COVID-19 大流行期间针对孕妇的暴力行为的发生率。检索了 Medline、Scopus、Web of Science 和 Google Scholar。两位独立作者使用 "暴力、妊娠、COVID-19 "关键词对2019年12月至2022年12月期间发表的所有观察性文章进行了评估。采用纽卡斯尔-渥太华质量评估量表对主要研究进行了质量评估,10 篇符合条件的文章被纳入本综述。经审查,采用随机效应模型估计 COVID-19 大流行期间孕妇的暴力发生率为 23% [95% 置信区间 (CI) =18 至 29%]。其中,59%(95% CI = 13%至 105%)归因于语言行为暴力,30%(95% CI = 17%至 42%)归因于情感暴力,14%(95% CI = 8%至 20%)归因于性暴力,11%(95% CI = 6%至 17%)归因于身体暴力。结果表明,在 COVID-19 大流行期间和之前,孕妇的暴力发生率并无不同。然而,行为-语言暴力、情感暴力、身体暴力和性暴力是最常见的暴力形式。
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引用次数: 0
Pregabalin dependence - A rising concern 普瑞巴林依赖症--日益严重的问题
Pub Date : 2024-02-16 DOI: 10.4103/ipj.ipj_179_23
Seema Rani, M. S. Bhatia
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引用次数: 0
Association between impulsivity and depressive symptoms in recently detoxified patients with alcohol dependence 新近戒酒的酒精依赖症患者的冲动性与抑郁症状之间的关系
Pub Date : 2024-02-15 DOI: 10.4103/ipj.ipj_61_23
Diptadhi Mukherjee, Kangkan Pathak, J. Mahadevan, Gopal Agarwal, Santanu Nath, Anantprakash Siddharthkumar Saraf
Depression and impulsivity are etiologically linked to alcohol dependence (AD) and are known to affect course and outcomes. The relationship between impulsivity and depressive symptoms has been investigated only in a few studies of individuals with AD. This study aimed to explore the association between impulsivity and depressive symptoms in patients with AD. Our study was conducted in the inpatient setup of a tertiary care psychiatry institute. The study design is cross-sectional. The Barratt Impulsiveness Scale (BIS-11) and stop signal task (SST) were used to assess levels of global impulsivity and behavioral impulsivity, respectively, among 60 recently detoxified inpatients with AD. The Hamilton Depression Rating Scale (HAM-D) was used to measure depressive symptoms. The results were analyzed to examine the association of depressive symptoms with impulsivity. Pearson’s coefficient of correlation or Spearman’s rank correlation and linear regression analysis were performed to explore the association between quantitative variables. Patients with higher HAM-D scores were found to have significantly higher score on all three subscales of the BIS-11. The attention impulsivity subscale had the strongest correlations (r = 0.53, P < 0.001). Depressive symptoms were more strongly correlated with cognitive impulsivity (r = 0.54, P< 0.0001) compared with motor impulsivity and were not significantly associated with behavioral impulsivity. Adjusting for other variables, cognitive impulsivity was found to be the strongest predictor of the severity of depressive symptoms. The study showed a strong association between impulsivity and depressive symptoms in individuals with AD. This relationship may apply more to cognitive impulsivity, reflecting the role of impulsive decisions compared with impulsive actions.
抑郁和冲动在病因学上与酒精依赖症(AD)有关,并且已知会影响病程和结果。只有少数针对酒精依赖症患者的研究调查了冲动性与抑郁症状之间的关系。 本研究旨在探讨 AD 患者的冲动性与抑郁症状之间的关系。 我们的研究是在一家三级精神病院的住院病人中进行的。研究设计为横断面。研究使用巴拉特冲动量表(BIS-11)和停止信号任务(SST)分别评估 60 名刚戒毒的 AD 住院患者的总体冲动和行为冲动水平。汉密尔顿抑郁评定量表(HAM-D)用于测量抑郁症状。分析结果旨在研究抑郁症状与冲动性之间的关联。通过皮尔逊相关系数或斯皮尔曼秩相关和线性回归分析来探讨定量变量之间的关联。 结果发现,HAM-D 分数较高的患者在 BIS-11 的三个分量表上的得分都明显较高。注意力冲动分量表的相关性最强(r = 0.53,P < 0.001)。与运动冲动相比,抑郁症状与认知冲动的相关性更强(r = 0.54,P< 0.0001),而与行为冲动的相关性不明显。对其他变量进行调整后发现,认知冲动是抑郁症状严重程度的最强预测因子。 该研究表明,注意力缺失症患者的冲动性与抑郁症状之间存在密切联系。这种关系可能更适用于认知冲动,反映了冲动性决定与冲动性行动相比所起的作用。
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引用次数: 0
Impact of subjective sleep quality on objective measures of neurocognitive dysfunction in patients with major depressive disorder 主观睡眠质量对重度抑郁症患者神经认知功能障碍客观测量指标的影响
Pub Date : 2024-02-15 DOI: 10.4103/ipj.ipj_136_23
E. Berdzenishvili, M. Roinishvili, M. Okruashvili, Vaja Kenchadze, E. Chkonia
Sleep disturbances are prevalent in major depressive disorder (MDD). MDD and sleep disturbances are both linked to cognitive impairments. Studies exploring the mechanisms and impact of sleep disturbances on neurocognitive functioning in depressed patients are lacking and proper assessment and therapeutic interventions for sleep disturbances are not part of clinical management of MDD. We investigated the association between subjective sleep quality and neurocognitive dysfunction in patients with MDD. Patients with moderate MDD episode were matched and assigned to two groups with poor and good sleep quality. We used Pittsburgh Sleep Quality Index (PSQI) to assess sleep quality. To measure frontotemporally mediated cognitive functioning, following tests were administered: Wisconsin Card Sorting Test (WCST) and degraded continuous performance test (CPT-DS). Two-tailed independent samples t tests or Mann–Whitney U tests and Pearson’s correlation coefficient were performed for the statistical analysis of sleep latency, sleep duration, overall sleep quality, CPT d’ value, WCST correct answers, errors, and perseverative errors. Participants with MDD and poor sleep quality performed worse on cognitive tests compared to patients with MDD and good sleep quality. Scores of subjective sleep on PSQI positively correlated with WCST errors (r (60) =0.8883 P = .001) and negatively correlated with WCST correct answers (r (60) = -.869 P = .001) and measures of CPT-DS d’ value (r (60) = -.9355 P = .001). Poor sleep quality, notably sleep duration and sleep latency, worsens the neurocognitive impairments of MDD patients. As these impairments are found to be associated with treatment outcomes, sleep disturbances should be additionally assessed and treated in MDD episode.
睡眠障碍在重度抑郁症(MDD)中很常见。重度抑郁症和睡眠障碍都与认知障碍有关。目前还缺乏探讨睡眠障碍的机制及其对抑郁症患者神经认知功能影响的研究,而且对睡眠障碍的适当评估和治疗干预并不是重度抑郁症临床治疗的一部分。 我们研究了多发性抑郁症患者的主观睡眠质量与神经认知功能障碍之间的关系。 我们将中度 MDD 患者进行配对,并将其分为睡眠质量差和睡眠质量好两组。我们使用匹兹堡睡眠质量指数(PSQI)来评估睡眠质量。为了测量额颞叶介导的认知功能,我们进行了以下测试:威斯康星卡片分类测试(WCST)和降级连续表现测试(CPT-DS)。对睡眠潜伏期、睡眠时间、总体睡眠质量、CPT d'值、WCST正确答案、错误和持久性错误进行双尾独立样本t检验或曼-惠特尼U检验和皮尔逊相关系数统计分析。 与睡眠质量好的 MDD 患者相比,睡眠质量差的 MDD 患者在认知测试中的表现更差。PSQI 的主观睡眠评分与 WCST 错误呈正相关(r (60) =0.8883 P = .001),与 WCST 正确答案呈负相关(r (60) = -.869 P = .001),与 CPT-DS d' 值的测量呈负相关(r (60) = -.9355 P = .001)。 睡眠质量差,尤其是睡眠持续时间和睡眠潜伏期差,会加重 MDD 患者的神经认知障碍。由于这些损伤与治疗效果相关,因此在 MDD 患者中应额外评估和治疗睡眠障碍。
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引用次数: 0
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Industrial Psychiatry Journal
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