Pub Date : 2023-11-30DOI: 10.26418/indonesian.v6i3.71213
Ari Widiyantoro, Harlia Harlia, Annisa Dyah Astari Putri
Pandan wangi (Pandanus amaryllifolius Roxb.) contains flavonoids, terpenoids, steroids, saponins, alkaloids and tannins which can be used as antifeedant compounds. This study aims to determine the antifeedant activity and to identify of secondary metabolites from pandan roots extract against Epilachna sparsa. The antifeedant activity test was carried out on the methanol extract and the partition yeild fraction. The research was carried out by maceration of pandan root which had been mashed into powder with methanol solution to obtain a methanol extract of 86.51 g. The extract was then separated by partitioning to obtain methanol fraction, ethyl acetate fraction, dichloromethane fraction and n-hexane fraction. The methanol extract and fraction from partition results were then tested for antifeedant activity against Epilachna sparsa. The results showed that at a concentration of 6% the methanol extract had an antifeedant activity of 59.37 ± 2.11 % against Epilachna sparsa. The fractions resulting from the partition included methanol, ethyl acetate, dichloromethane and n-hexane fractions at a concentration of 6% respectively showing antifeedant activity of 81.25 ± 3.56 %; 75.00 ± 2.99 %; 37.50 ± 3.77 % and 21.18 ±1.23 %. Based on the antifeedant activity test results, the methanol fraction showed the best activity. Furthermore, the methanol fraction was separated and purified by chromatographic techniques. The isolate obtained was 53.11 mg in the form of white needle crystals and had a melting point of 135-138oC. The isolate based on the phytochemical test showed positive for flavonoid
{"title":"METABOLIT SEKUNDER DARI FRAKSI AKTIF AKAR PANDAN (Pandanus amaryllifolius roxb.) YANG BERSIFAT ANTIFEEDANT TERHADAP Epilachna sparsa (SECONDARY METABOLITES OF THE ACTIVE FRACTION OF PANDAN ROOT (Pandanus amaryllifolius roxb.) AS ANTIFEEDANT AGAINST Epilachna sparsa)","authors":"Ari Widiyantoro, Harlia Harlia, Annisa Dyah Astari Putri","doi":"10.26418/indonesian.v6i3.71213","DOIUrl":"https://doi.org/10.26418/indonesian.v6i3.71213","url":null,"abstract":"Pandan wangi (Pandanus amaryllifolius Roxb.) contains flavonoids, terpenoids, steroids, saponins, alkaloids and tannins which can be used as antifeedant compounds. This study aims to determine the antifeedant activity and to identify of secondary metabolites from pandan roots extract against Epilachna sparsa. The antifeedant activity test was carried out on the methanol extract and the partition yeild fraction. The research was carried out by maceration of pandan root which had been mashed into powder with methanol solution to obtain a methanol extract of 86.51 g. The extract was then separated by partitioning to obtain methanol fraction, ethyl acetate fraction, dichloromethane fraction and n-hexane fraction. The methanol extract and fraction from partition results were then tested for antifeedant activity against Epilachna sparsa. The results showed that at a concentration of 6% the methanol extract had an antifeedant activity of 59.37 ± 2.11 % against Epilachna sparsa. The fractions resulting from the partition included methanol, ethyl acetate, dichloromethane and n-hexane fractions at a concentration of 6% respectively showing antifeedant activity of 81.25 ± 3.56 %; 75.00 ± 2.99 %; 37.50 ± 3.77 % and 21.18 ±1.23 %. Based on the antifeedant activity test results, the methanol fraction showed the best activity. Furthermore, the methanol fraction was separated and purified by chromatographic techniques. The isolate obtained was 53.11 mg in the form of white needle crystals and had a melting point of 135-138oC. The isolate based on the phytochemical test showed positive for flavonoid","PeriodicalId":13554,"journal":{"name":"Indonesian Journal of Pure and Applied Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139199852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-01DOI: 10.26418/indonesian.v6i3.65513
Chaleb Paul Maanari, Sanusi Gugule, Feti Fatimah, Aisyiah Restutiningsih Putri Utami, Mustapa Mustapa, Stefan Marco Rumengan, Miftahul Jannah, Jakub Saddam Akbar, Djois Sugiaty Rintjap
Research has been carried out on the effect of potassium hydroxide catalyst concentration on the yield of coconut oil (Cocos nucifera) transesterification and continued to characterize the reaction results. The concentration of potassium hydroxide used was 1, 2, and 3% by weight of coconut oil with ethanol as the reactant. The data processing used was the one-way analysis of variation and its characterization from a physicochemical perspective, followed by the analysis of gas chromatography-mass spectroscopy (GCSM) and infrared spectrophotometry. Based on the data processing results, potassium hydroxide concentrations of 1, 2, and 3% did not affect the yield of the transesterification reaction of coconut oil, and the results were 74.5264%, 71.9330%, and 69.0420%. The characterization results show that the physicochemical properties of the reaction products, such as acid number, density, and viscosity, comply with the Indonesian National Standard (SNI) for biodiesel. The results of the GCMS analysis showed that nine peaks were dominated by ethyl laurate.
{"title":"EFFECT OF POTASSIUM HYDROXIDE CONCENTRATION AS A CATALYST ON THE YIELD OF COCONUT OIL (Cocos nucifera) TRANSESTERIFICATION","authors":"Chaleb Paul Maanari, Sanusi Gugule, Feti Fatimah, Aisyiah Restutiningsih Putri Utami, Mustapa Mustapa, Stefan Marco Rumengan, Miftahul Jannah, Jakub Saddam Akbar, Djois Sugiaty Rintjap","doi":"10.26418/indonesian.v6i3.65513","DOIUrl":"https://doi.org/10.26418/indonesian.v6i3.65513","url":null,"abstract":"Research has been carried out on the effect of potassium hydroxide catalyst concentration on the yield of coconut oil (Cocos nucifera) transesterification and continued to characterize the reaction results. The concentration of potassium hydroxide used was 1, 2, and 3% by weight of coconut oil with ethanol as the reactant. The data processing used was the one-way analysis of variation and its characterization from a physicochemical perspective, followed by the analysis of gas chromatography-mass spectroscopy (GCSM) and infrared spectrophotometry. Based on the data processing results, potassium hydroxide concentrations of 1, 2, and 3% did not affect the yield of the transesterification reaction of coconut oil, and the results were 74.5264%, 71.9330%, and 69.0420%. The characterization results show that the physicochemical properties of the reaction products, such as acid number, density, and viscosity, comply with the Indonesian National Standard (SNI) for biodiesel. The results of the GCMS analysis showed that nine peaks were dominated by ethyl laurate.","PeriodicalId":13554,"journal":{"name":"Indonesian Journal of Pure and Applied Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135410334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-01DOI: 10.26418/indonesian.v6i3.67697
Charlena Charlena, Yessie Widya Sari, Wulan Islamia
Dental caries can cause porous cavities and even broken teeth, necessitating natural teeth extraction and replacement with implants. Fluorapatite, a dental implant material, can be synthesized from snail shells containing 98% calcium carbonate. This study aims to identify the characteristics of fluorapatite and determine the effect of variations in sintering temperature on the synthesis of fluorapatite made from snail shells using the sol-gel method. Variations of sintering temperature used are 700, 900, and 1100 °C. The results showed that fluorapatite synthesized with the sintering temperature of 900 °C demonstrates the highest crystallinity, according to the diffractogram results, there is an 83% presence of the apatite phase at an angle of 31.8126°, with a crystal size of 79 nm and a particle size of 0.5 µm. Fourier-transform infrared spectroscopy analysis on the sample showed the presence of OH, OH−F, and PO43− functional groups. The sample showed a spongy surface morphology with hexagonal-shaped flowers—a Ca/P molarity ratio 1.67
{"title":"VARIATION OF SINTERING TEMPERATURE IN THE SYNTHESIS OF FLUORAPATITE FROM SNAIL SHELLS (Achatina fulica) USING THE SOL-GEL METHOD","authors":"Charlena Charlena, Yessie Widya Sari, Wulan Islamia","doi":"10.26418/indonesian.v6i3.67697","DOIUrl":"https://doi.org/10.26418/indonesian.v6i3.67697","url":null,"abstract":"Dental caries can cause porous cavities and even broken teeth, necessitating natural teeth extraction and replacement with implants. Fluorapatite, a dental implant material, can be synthesized from snail shells containing 98% calcium carbonate. This study aims to identify the characteristics of fluorapatite and determine the effect of variations in sintering temperature on the synthesis of fluorapatite made from snail shells using the sol-gel method. Variations of sintering temperature used are 700, 900, and 1100 °C. The results showed that fluorapatite synthesized with the sintering temperature of 900 °C demonstrates the highest crystallinity, according to the diffractogram results, there is an 83% presence of the apatite phase at an angle of 31.8126°, with a crystal size of 79 nm and a particle size of 0.5 µm. Fourier-transform infrared spectroscopy analysis on the sample showed the presence of OH, OH−F, and PO43− functional groups. The sample showed a spongy surface morphology with hexagonal-shaped flowers—a Ca/P molarity ratio 1.67","PeriodicalId":13554,"journal":{"name":"Indonesian Journal of Pure and Applied Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135412363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-31DOI: 10.26418/indonesian.v6i3.66363
Teguh Pambudi, Hilman Imadul Umam
The synthesis of magnetite-modified natural zeolite has been carried out using two techniques, namely coprecipitation and physical mixing. The characteristics (crystallinity, pore characteristics, and recovery capabilities) of the resulting composites are compared. In addition, the effect of the Fe3O4 fraction (25.0% w/w, 33.3% w/w, and 50.0% w/w) on the composite characteristics was also evaluated. The results showed that the natural zeolite/Fe3O4 prepared using the coprecipitation technique showed better distribution of Fe3O4 than the physical mixing technique. It was observed that the natural zeolite's XRD peak intensity decreased as the Fe3O4 content increased. In accordance with the N2 adsorption-desorption isotherm, the pore spaces of the natural zeolite have been found to be filled by suspended Fe3O4 particles. Therefore, both natural zeolite/Fe3O4 prepared by coprecipitation and physical mixing had smaller pore diameters than washed natural zeolite. Then, in terms of recovery ability, natural zeolite/Fe3O4 prepared using the coprecipitation technique has greater recovery ability than natural zeolite/Fe3O4 prepared by physical mixing, with an increase in the Fe3O4 percentage typically enhancing the composite's recovery ability.
{"title":"SYNTHESIS OF MAGNETITE-MODIFIED NATURAL ZEOLITE USING COPRECIPITATION AND PHYSICAL MIXING TECHNIQUES","authors":"Teguh Pambudi, Hilman Imadul Umam","doi":"10.26418/indonesian.v6i3.66363","DOIUrl":"https://doi.org/10.26418/indonesian.v6i3.66363","url":null,"abstract":"The synthesis of magnetite-modified natural zeolite has been carried out using two techniques, namely coprecipitation and physical mixing. The characteristics (crystallinity, pore characteristics, and recovery capabilities) of the resulting composites are compared. In addition, the effect of the Fe3O4 fraction (25.0% w/w, 33.3% w/w, and 50.0% w/w) on the composite characteristics was also evaluated. The results showed that the natural zeolite/Fe3O4 prepared using the coprecipitation technique showed better distribution of Fe3O4 than the physical mixing technique. It was observed that the natural zeolite's XRD peak intensity decreased as the Fe3O4 content increased. In accordance with the N2 adsorption-desorption isotherm, the pore spaces of the natural zeolite have been found to be filled by suspended Fe3O4 particles. Therefore, both natural zeolite/Fe3O4 prepared by coprecipitation and physical mixing had smaller pore diameters than washed natural zeolite. Then, in terms of recovery ability, natural zeolite/Fe3O4 prepared using the coprecipitation technique has greater recovery ability than natural zeolite/Fe3O4 prepared by physical mixing, with an increase in the Fe3O4 percentage typically enhancing the composite's recovery ability.","PeriodicalId":13554,"journal":{"name":"Indonesian Journal of Pure and Applied Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135869247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tabernaemontana macrocarpa Jack is one of the plants from the Tabernaemontana genus in the Apocynaceae family. Some compounds from the genus Tabernaemontana have shown interesting biological activities. Unfortunately, information about secondary metabolites and the bioactivity of T. macrocarpa Jack is limited. This study was conducted to determine the total phenolics and flavonoids contents of seeds flesh and fruit of T. montana together with their antioxidant activity. The seeds flesh and fruit of T. macrocarpa were extracted by maceration using methanol. Phytochemical tests showed that methanol extracts of seeds flesh and fruit contain alkaloids, flavonoids, and polyphenols. Total phenols and flavonoids were determined quantitatively by spectrometry and it showed that the seeds flesh contained more polyphenolics and flavonoids than the fruit. The results of the antioxidant activity showed that the seeds flesh and fruit extracts did not have antioxidant activity since their IC50 values were > 500 mg/L.
{"title":"PENETAPAN KADAR FLAVONOID, FENOLIK DAN AKTIVITAS ANTIOKSIDAN EKSTRAK BUAH Tabernaemontana Macrocarpa JACK ASAL KALIMANTAN BARAT (DETERMINATION OF FLAVONOID, PHENOLIC, AND ANTIOXIDANT ACTIVITY OF Tabernaemontana Macrocarpa JACK FRUIT EXTRACT FROM WEST KALIMANTAN)","authors":"Andi Hairil Alimuddin, Rudiyansyah Rudiyansyah, Masriani Masriani","doi":"10.26418/indonesian.v6i3.63749","DOIUrl":"https://doi.org/10.26418/indonesian.v6i3.63749","url":null,"abstract":"Tabernaemontana macrocarpa Jack is one of the plants from the Tabernaemontana genus in the Apocynaceae family. Some compounds from the genus Tabernaemontana have shown interesting biological activities. Unfortunately, information about secondary metabolites and the bioactivity of T. macrocarpa Jack is limited. This study was conducted to determine the total phenolics and flavonoids contents of seeds flesh and fruit of T. montana together with their antioxidant activity. The seeds flesh and fruit of T. macrocarpa were extracted by maceration using methanol. Phytochemical tests showed that methanol extracts of seeds flesh and fruit contain alkaloids, flavonoids, and polyphenols. Total phenols and flavonoids were determined quantitatively by spectrometry and it showed that the seeds flesh contained more polyphenolics and flavonoids than the fruit. The results of the antioxidant activity showed that the seeds flesh and fruit extracts did not have antioxidant activity since their IC50 values were > 500 mg/L.","PeriodicalId":13554,"journal":{"name":"Indonesian Journal of Pure and Applied Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135869252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-31DOI: 10.26418/indonesian.v6i3.67301
Khoirotun Nafillah, Chairil Anwar
Curcumin is the main component of turmeric with various biological activities, one of which is antidiabetic. However, curcumin has low bioavailability and fast metabolism, so repeated doses are required if used as a medicine. Curcumin analogs have better bioavailability than curcumin. This study aims to synthesize curcumin analog from 4-methoxybenzaldehyde and monoketone (cyclohexanone and cyclopentanone), and their synergism effect using iodine method. The compounds A and B have been synthesized using Claisen-Schmidt condensation from benzaldehyde derivatives using KOH 8% and ethanol as solvent. The results showed that the curcumin analogs A and B were yellow solids with yields of 31,13% and 31,87%, respectively. The structure of products was characterized by FTIR, DI-MS, 1H- and 13C-NMR, showed that curcumin analogs A is 2,6-bis(4-methoxybenzylidene)cyclohexanone and curcumin analogs B is 2,6-bis(4-methoxybenzylidene)cyclopentanone. α-amylase inhibition assay of curcumin analogs A and B were performed by formation of amylum-iodine complex with UV-vis spectrophotometer at wavelength of 600 nm, showed that 33,03% and 91,5% at concentration 1 mM. Synergy studies with ferulic acid indicated that compound A 99,23% at a concentration ratio (1:8) and B 99,14% (1:4). This indicates a synergy between curcumin analogs and ferulic acid as an inhibitor of the α-amylase.
{"title":"KARAKTERISASI DAN STUDI SINERGI ANALOG KURKUMIN DARI SENYAWA 4-METOKSIBENZALDEHIDA SEBAGAI ANTIDIABETES DENGAN METODE IODIN (CHARACTERIZATION AND SYNERGY STUDY OF CURCUMIN ANALOGS FROM 4-METHOXYBENZALDEHYDE COMPOUND AS AN ANTIDIABETIC USING IODINE METHOD)","authors":"Khoirotun Nafillah, Chairil Anwar","doi":"10.26418/indonesian.v6i3.67301","DOIUrl":"https://doi.org/10.26418/indonesian.v6i3.67301","url":null,"abstract":"Curcumin is the main component of turmeric with various biological activities, one of which is antidiabetic. However, curcumin has low bioavailability and fast metabolism, so repeated doses are required if used as a medicine. Curcumin analogs have better bioavailability than curcumin. This study aims to synthesize curcumin analog from 4-methoxybenzaldehyde and monoketone (cyclohexanone and cyclopentanone), and their synergism effect using iodine method. The compounds A and B have been synthesized using Claisen-Schmidt condensation from benzaldehyde derivatives using KOH 8% and ethanol as solvent. The results showed that the curcumin analogs A and B were yellow solids with yields of 31,13% and 31,87%, respectively. The structure of products was characterized by FTIR, DI-MS, 1H- and 13C-NMR, showed that curcumin analogs A is 2,6-bis(4-methoxybenzylidene)cyclohexanone and curcumin analogs B is 2,6-bis(4-methoxybenzylidene)cyclopentanone. α-amylase inhibition assay of curcumin analogs A and B were performed by formation of amylum-iodine complex with UV-vis spectrophotometer at wavelength of 600 nm, showed that 33,03% and 91,5% at concentration 1 mM. Synergy studies with ferulic acid indicated that compound A 99,23% at a concentration ratio (1:8) and B 99,14% (1:4). This indicates a synergy between curcumin analogs and ferulic acid as an inhibitor of the α-amylase.","PeriodicalId":13554,"journal":{"name":"Indonesian Journal of Pure and Applied Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135869853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-30DOI: 10.26418/indonesian.v6i3.69965
Muhamad Agus Wibowo, Ninda Kumala Sari, Puji Ardiningsih, Afghani Jayuska
Rhizophora apiculata is a plant that is widely found in mangrove forests in Sukadana subdistrict, and has the potential to inhibit of Escherichia coli. This research aims to determine the activity of R. apiculata which grows in the Sukadana mangrove forest in inhibiting E. coli. The leaves of R. apiculata were macerated with methanol solvent, partitioned into three fractions (n-hexane fraction, dichloromethane fraction, and methanol fraction), and tested for phytochemical screening. The results of phytochemical screening of R. apiculata leaves were positive for flavonoids, alkaloids, phenolics, terpenoids, tannins, and saponins. The potential of R. apiculata leaf samples in inhibiting bacterial growth was measured by the size of the clear zone in the antibacterial test with the agar well diffusion method that uses variations in concentration, namely 250 mg/mL, 125 mg/mL, and 62.5 mg/mL. Based on the research results, it is known that R. apiculata leaves can inhibit the growth of the test bacteria with a minimum inhibitory concentration for methanol extract of 250 mg/mL. The methanol and dichloromethane fractions had minimum inhibitory concentrations of 125 mg/mL and 250 mg/mL respectively, while the n-hexane fraction did not inhibit at all test concentrations. So it can be concluded that the leaves of R. apiculata have the potential as an alternative for antibacterial active compounds
{"title":"DAYA HAMBAT EKSTRAK DAUN MANGROVE (Rhizophora apiculata) ASAL PESISIR SUKADANA TERHADAP BAKTERI Escherichia coli (INHIBITION THE LEAF EXTRACT OF Rhizophora apiculata FROM THE SUKADANA COAST AGAINST Escherichia coli)","authors":"Muhamad Agus Wibowo, Ninda Kumala Sari, Puji Ardiningsih, Afghani Jayuska","doi":"10.26418/indonesian.v6i3.69965","DOIUrl":"https://doi.org/10.26418/indonesian.v6i3.69965","url":null,"abstract":"Rhizophora apiculata is a plant that is widely found in mangrove forests in Sukadana subdistrict, and has the potential to inhibit of Escherichia coli. This research aims to determine the activity of R. apiculata which grows in the Sukadana mangrove forest in inhibiting E. coli. The leaves of R. apiculata were macerated with methanol solvent, partitioned into three fractions (n-hexane fraction, dichloromethane fraction, and methanol fraction), and tested for phytochemical screening. The results of phytochemical screening of R. apiculata leaves were positive for flavonoids, alkaloids, phenolics, terpenoids, tannins, and saponins. The potential of R. apiculata leaf samples in inhibiting bacterial growth was measured by the size of the clear zone in the antibacterial test with the agar well diffusion method that uses variations in concentration, namely 250 mg/mL, 125 mg/mL, and 62.5 mg/mL. Based on the research results, it is known that R. apiculata leaves can inhibit the growth of the test bacteria with a minimum inhibitory concentration for methanol extract of 250 mg/mL. The methanol and dichloromethane fractions had minimum inhibitory concentrations of 125 mg/mL and 250 mg/mL respectively, while the n-hexane fraction did not inhibit at all test concentrations. So it can be concluded that the leaves of R. apiculata have the potential as an alternative for antibacterial active compounds","PeriodicalId":13554,"journal":{"name":"Indonesian Journal of Pure and Applied Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136069196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-31DOI: 10.26418/indonesian.v6i2.62858
Illen Stevani, T. A. Zaharah, I. H. Silalahi
Cement is one of the building blocks of concrete. However, it releases about one ton of carbon dioxide (CO2) gas for every ton of cement produced. Therefore, it is necessary to replace cement in the manufacture of concrete. It is known that a mixture of fly ash and calcium carbide waste has a chemical composition that resembles cement containing silica, alumina, and calcium oxide compounds so that it has the potential to replace cement in making self-compacting concrete. This research was conducted by utilising fly ash waste and carbide waste as additional materials to replace the use of cement by 35% in self compacting concrete. The composition of the waste used in the concrete mix in this study consisted of 25% fly ash waste and 10% calcium carbide waste. Analysis of the elemental composition of self-compacting concrete containing fly ash and calcium carbide waste was obtained from XRF data, the compressive strength of self-compacting concrete samples was tested, their resistance in acid and salt media was studied through the results of compressive strength test analysis, then compared with self-compacting concrete containing 100% cement. The XRF results showed that the elemental composition of the mixture of fly ash, calcium carbide waste, and cement was similar to that of cement alone, but the CaO and SiO2 content of the mixture was still higher than that of cement alone. Based on the compressive strength test analysis results, it was found that the compressive strength values of the self-compacting concrete samples were lower than the compressive strength values of the control of self-compacting concrete samples (cement only). Self-compacting concrete samples soaked in acid and salt media for 28 days showed a decrease in compressive strength, both in self compacting concrete containing a mixture of fly ash, calcium carbide waste, and cement, and concrete containing only cement. The compressive strength values of the fly ash and calcium carbide waste on self-compacting concrete samples in this study were at the range of 28 MPa to 29 MPa, still within the SNI 2847-2019 quality standard, which is the normal concrete quality standard with a compressive force of 15-30 MPa, even though they have been exposed to acid or salt. This allows efforts in replacing cement in self compacting concrete by adding the composition of fly ash waste and calcium carbide waste.
{"title":"KAJIAN KETAHANAN BETON DENGAN TAMBAHAN CAMPURAN FLY ASH DAN LIMBAH KARBIT DALAM MEDIA ASAM DAN GARAM (DURABILITY STUDY OF SELF COMPACTING CONCRETE WITH ADDED A MIXTURE OF FLY ASH AND CALCIUM CARBIDE WASTE IN ACID AND SALT MEDIUM)","authors":"Illen Stevani, T. A. Zaharah, I. H. Silalahi","doi":"10.26418/indonesian.v6i2.62858","DOIUrl":"https://doi.org/10.26418/indonesian.v6i2.62858","url":null,"abstract":"Cement is one of the building blocks of concrete. However, it releases about one ton of carbon dioxide (CO2) gas for every ton of cement produced. Therefore, it is necessary to replace cement in the manufacture of concrete. It is known that a mixture of fly ash and calcium carbide waste has a chemical composition that resembles cement containing silica, alumina, and calcium oxide compounds so that it has the potential to replace cement in making self-compacting concrete. This research was conducted by utilising fly ash waste and carbide waste as additional materials to replace the use of cement by 35% in self compacting concrete. The composition of the waste used in the concrete mix in this study consisted of 25% fly ash waste and 10% calcium carbide waste. Analysis of the elemental composition of self-compacting concrete containing fly ash and calcium carbide waste was obtained from XRF data, the compressive strength of self-compacting concrete samples was tested, their resistance in acid and salt media was studied through the results of compressive strength test analysis, then compared with self-compacting concrete containing 100% cement. The XRF results showed that the elemental composition of the mixture of fly ash, calcium carbide waste, and cement was similar to that of cement alone, but the CaO and SiO2 content of the mixture was still higher than that of cement alone. Based on the compressive strength test analysis results, it was found that the compressive strength values of the self-compacting concrete samples were lower than the compressive strength values of the control of self-compacting concrete samples (cement only). Self-compacting concrete samples soaked in acid and salt media for 28 days showed a decrease in compressive strength, both in self compacting concrete containing a mixture of fly ash, calcium carbide waste, and cement, and concrete containing only cement. The compressive strength values of the fly ash and calcium carbide waste on self-compacting concrete samples in this study were at the range of 28 MPa to 29 MPa, still within the SNI 2847-2019 quality standard, which is the normal concrete quality standard with a compressive force of 15-30 MPa, even though they have been exposed to acid or salt. This allows efforts in replacing cement in self compacting concrete by adding the composition of fly ash waste and calcium carbide waste.","PeriodicalId":13554,"journal":{"name":"Indonesian Journal of Pure and Applied Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88324264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-31DOI: 10.26418/indonesian.v6i2.62269
Khairunnisa Asyari, A. Jayuska, M. A. Wibowo, P. Ardiningsih
Agarwood buaya (Aetoxylon sympetalum) is a Kalimantan endemic plant whose utilization has not been optimal. This plant has potential as an anti-termite, one of which is sapwood. This study aims to determine the content of secondary metabolites from the results of phytochemical screening, components of agarwood buaya sapwood based on GC-MS analysis fraction n-hexane and anti-termite activity against subterranean termites (Coptotermes sp.). Research that has been done is divided into four steps, maceration and fractionation, phytochemical screening, GC-MS analysis, and testing the activity of termites using a forced feeding test method. Crude methanol extract from 1 kg of dried agarwood buaya sapwood was 240.787 g (24.0787%), consisting of 0.8339% n-hexane fraction, 86.3663% chloroform fraction, and 0.7571% methanol fraction. The results of phytochemical screening on agarwood buaya sapwood extract showed that it contained flavonoid, terpenoid, steroid, and phenolic compounds. Identification of the components of agarwood buaya sapwood fraction n-hexane through GC-MS yielded compounds a4-chloro-6-methoxy-2-methylquinolin-8-amine (10.33%), stigmasterol among other (5.94%), n-hexa-decanoic acid (3.2%), 6-octa-decenoic acid (2.99%), and 1,2-Benzene-diol, 3,5-bis(1,1-dimethyl-ethyl) (2.01%). Termite activity test was carried out for 3 days with variations in the concentration of 0% (negative control), 0.1%, 0.2%, 0.3%, 0.4% (w/v), and 0.25% (v/v) (fibronil as positive control). The results of anti-termite testing show the most active fraction was the methanol fraction (LC50 0.146%) followed by the chloroform fraction (LC50 0.167%), methanol crude extract (LC50 0.192%), and the n-hexane fraction (LC50 0.208%).
{"title":"AKTIVITAS ANTIRAYAP DARI EKSTRAK METANOL GUBAL KAYU GAHARU BUAYA (Aetoxylon sympetalum) TERHADAP RAYAP TANAH (Coptotermes sp.) (ANTITERMITE ACTIVITY OF METHANOL EXTRACT AGARWOOD BUAYA (Aetoxylon sympetalum) ON SUBTERRANEAN TERMITES (Coptotermes sp.))","authors":"Khairunnisa Asyari, A. Jayuska, M. A. Wibowo, P. Ardiningsih","doi":"10.26418/indonesian.v6i2.62269","DOIUrl":"https://doi.org/10.26418/indonesian.v6i2.62269","url":null,"abstract":"Agarwood buaya (Aetoxylon sympetalum) is a Kalimantan endemic plant whose utilization has not been optimal. This plant has potential as an anti-termite, one of which is sapwood. This study aims to determine the content of secondary metabolites from the results of phytochemical screening, components of agarwood buaya sapwood based on GC-MS analysis fraction n-hexane and anti-termite activity against subterranean termites (Coptotermes sp.). Research that has been done is divided into four steps, maceration and fractionation, phytochemical screening, GC-MS analysis, and testing the activity of termites using a forced feeding test method. Crude methanol extract from 1 kg of dried agarwood buaya sapwood was 240.787 g (24.0787%), consisting of 0.8339% n-hexane fraction, 86.3663% chloroform fraction, and 0.7571% methanol fraction. The results of phytochemical screening on agarwood buaya sapwood extract showed that it contained flavonoid, terpenoid, steroid, and phenolic compounds. Identification of the components of agarwood buaya sapwood fraction n-hexane through GC-MS yielded compounds a4-chloro-6-methoxy-2-methylquinolin-8-amine (10.33%), stigmasterol among other (5.94%), n-hexa-decanoic acid (3.2%), 6-octa-decenoic acid (2.99%), and 1,2-Benzene-diol, 3,5-bis(1,1-dimethyl-ethyl) (2.01%). Termite activity test was carried out for 3 days with variations in the concentration of 0% (negative control), 0.1%, 0.2%, 0.3%, 0.4% (w/v), and 0.25% (v/v) (fibronil as positive control). The results of anti-termite testing show the most active fraction was the methanol fraction (LC50 0.146%) followed by the chloroform fraction (LC50 0.167%), methanol crude extract (LC50 0.192%), and the n-hexane fraction (LC50 0.208%).","PeriodicalId":13554,"journal":{"name":"Indonesian Journal of Pure and Applied Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81624361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-31DOI: 10.26418/indonesian.v6i2.65149
Diana Natasya, Marsella Oktavioni, Yusnaidar Yusnaidar, I. L. Tarigan
Miana plants (Coleus) are plants with compound interest types. Miana leaves have various bioactive compounds and are widely used to treat various diseases such as fever, colds, coughs, headaches, asthma, constipation, and skin diseases. There are several types of miana plants, such as Coleus scutellarioides (L.) Benth., Coleus aromaticus Benth., Coleus atropurpureus (L.) Benth. and Coleus blumei benth. This review aims to review the content of bioactive compounds and chemical constituents of the plant and its potential as a drug candidate. The method applied to the review articles is in the form of literature studies from national and international journals. Based on the data used, the n-hexane extract of miana leaves found 11 chemical compounds. Then based on the phytochemical screening of miana plants, several bioactive compounds were produced such as sterols, terpenoids, alkaloids, phenols, flavonoids, amino acids, glycosides, lactones, catechols, and tannins. The function of the Coleus aromaticus plant is as an antioxidant, antiepileptic, antiurolytic, anticancer, antidiabetic, anthelmintic, antiviral, antiprotozoal activity, the inhibitory activity of microorganisms, against digestive diseases, respiratory disorders, and against cardiovascular disorders
{"title":"REVIEW SENYAWA BIOAKTIF DAN KONSTITUEN KIMIA DARI TANAMAN COLEUS SEBAGAI KANDIDAT OBAT (REVIEW OF BIOACTIVE COMPOUNDS AND CHEMICAL CONSTITUENTS FROM COLEUS PLANTS AS DRUG CANDIDATES)","authors":"Diana Natasya, Marsella Oktavioni, Yusnaidar Yusnaidar, I. L. Tarigan","doi":"10.26418/indonesian.v6i2.65149","DOIUrl":"https://doi.org/10.26418/indonesian.v6i2.65149","url":null,"abstract":"Miana plants (Coleus) are plants with compound interest types. Miana leaves have various bioactive compounds and are widely used to treat various diseases such as fever, colds, coughs, headaches, asthma, constipation, and skin diseases. There are several types of miana plants, such as Coleus scutellarioides (L.) Benth., Coleus aromaticus Benth., Coleus atropurpureus (L.) Benth. and Coleus blumei benth. This review aims to review the content of bioactive compounds and chemical constituents of the plant and its potential as a drug candidate. The method applied to the review articles is in the form of literature studies from national and international journals. Based on the data used, the n-hexane extract of miana leaves found 11 chemical compounds. Then based on the phytochemical screening of miana plants, several bioactive compounds were produced such as sterols, terpenoids, alkaloids, phenols, flavonoids, amino acids, glycosides, lactones, catechols, and tannins. The function of the Coleus aromaticus plant is as an antioxidant, antiepileptic, antiurolytic, anticancer, antidiabetic, anthelmintic, antiviral, antiprotozoal activity, the inhibitory activity of microorganisms, against digestive diseases, respiratory disorders, and against cardiovascular disorders","PeriodicalId":13554,"journal":{"name":"Indonesian Journal of Pure and Applied Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74415963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：