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Tubogram, A Useful Investigation for Evaluation of Patients Post Cholecystostomy Drain for Acute Cholecystitis, Single Centre Experience 输卵管造影,评价急性胆囊炎胆囊造瘘术后引流的有用调查,单中心经验
Pub Date : 2023-01-02 DOI: 10.59657/2837-8172.brs.23.006
Badreldin Mohamed, George Simmons, Khalid M. Bhatti, S. Taha, Abdalla Hassan, Muhammad Chauhan, S. Babikir, M. Mohamed, D. Mirghani, R. Canelo
Background: Laparoscopic cholecystectomy (LC) is the gold standard treatment for cholecystitis. However, for co-morbid or unstable patients, a less invasive approach can be adopted such as cholecystostomy drain (CD) insertion. CD can be a bridging operation or can be used as a definitive treatment if patient unsuitable for surgery. Methods: Retrospective study of patients who had Tubogram at Cumberland Infirmary, post CD for non-malignant cause between January 2019 and January 2022, comparing their outcome with the patients who did not undergo tubogram investigation. Patient data list collected from information department, Cumberland Infirmary. Results: Cholecystostomy drain placed for 58 patients; 21 patient (36.21%) had tubogram. Of the 58,44 patients (75.86%) had one CD; only 10 patients (22.73%) of them had tubogram. 14 patients had more than one CD (11 patient of them had tubogram). 66.67% patients had tubogram at 3-4 weeks following CD insertion. Outcome of tubogram patients was 47.62% (n=10) had Laparoscopic Cholecystectomy (LC) 6 weeks after cholecystostomy drain removal and 28.57% (n=6) had Endoscopic retrograde cholangiography then Laparoscopic Cholecystectomy. Non-tubogram patients’ group had more visits to same day emergency clinic comparing to tubogram patients’ group. Conclusion: Tubogram is a useful, cheap, non-invasive test linked with lower recurrence rate of cholecystitis symptoms after removal of CD; it is also associated with earlier CD removal. We recommend that tubogram should be a routine investigation for all patients three to four weeks post CD insertion.
背景:腹腔镜胆囊切除术(LC)是治疗胆囊炎的金标准。然而,对于合并症或不稳定的患者,可以采用侵入性较小的方法,如胆囊造口引流管(CD)插入。CD可以作为一种桥接手术,如果患者不适合手术,也可以作为一种明确的治疗方法。方法:回顾性研究2019年1月至2022年1月在坎伯兰医院(Cumberland hospital)接受非恶性原因CD后输卵管造影检查的患者,将其结果与未接受输卵管造影检查的患者进行比较。从坎伯兰医院信息部收集的患者数据列表。结果:胆囊造口引流58例;输卵管造影21例(36.21%)。58例患者中,44例(75.86%)有1例CD;其中仅有10例(22.73%)行输卵管造影。14例有1个以上CD(其中11例有输卵管造影)。66.67%的患者在CD插入后3-4周行输卵管造影。输卵管造影患者中,47.62% (n=10)在胆囊造瘘6周后行腹腔镜胆囊切除术(LC), 28.57% (n=6)行内镜逆行胆管造影后行腹腔镜胆囊切除术。非输卵管造影组当日急诊就诊次数高于输卵管造影组。结论:输卵管造影是一种实用、廉价、无创的检查方法,胆囊切除术后胆囊炎症状复发率较低;它也与早期的乳糜泻清除有关。我们建议所有患者在CD插入后3 - 4周进行输卵管造影检查。
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引用次数: 0
Bladder Paraganglioma: Report of Two Cases and A Literature Review 膀胱副神经节瘤2例报告并文献复习
Pub Date : 2023-01-02 DOI: 10.59657/2837-8172.brs.23.004
A. Slaoui, Babty Mouftah, A. Slaoui, Y. Himmi, Amine El Affari, O. Zineddine, Taha Yassine Abboudech, Z. Bernoussi, T. Karmouni, K. El khader, Aziz Baydada, A. Kharbach, A. Koutani, Ahmen Ibn Attya Andaloussi
Objective: We report two incidental cases of bladder paraganglioma and a review of the literature published to date. Methods: Medline was searched for the last 10 years for the terms "paraganglioma" and "urinary" and "bladder". Results: Bladder paraganglioma (BP) is extremely rare. It represents 10% of all paragangliomas and concerns less than 0.06% of bladder tumors. Often discovered by chance, it can nevertheless be symptomatic, particularly during micturition. The most common symptoms are hematuria, hypertension and headache. About 14% of these tumors are malignant and radio-chemically resistant. Surgery is therefore the cornerstone of treatment. We recommend, cystoscopy, partial cystectomy and regular follow-up based on regular cystoscopy and imaging. Their rarity explains why, at present, there are no recommendations for treatment and monitoring. However, their risk of malignancy recurrence and metastasis requires regular and long-term follow-up. Conclusions: Bladder paragangliomas are rare tumors. Treatment should be based on partial cystectomy and their follow-up should be regular.
目的:我们报告两例膀胱副神经节瘤的偶发病例,并回顾迄今为止发表的文献。方法:在Medline检索近10年的“副神经节瘤”、“泌尿系统”和“膀胱”等术语。结果:膀胱副神经节瘤(BP)极为罕见。它占所有副神经节瘤的10%,占膀胱肿瘤的不到0.06%。它通常是偶然发现的,但也可能是有症状的,特别是在排尿时。最常见的症状是血尿、高血压和头痛。这些肿瘤中约有14%是恶性的,具有放射化学抗性。因此,手术是治疗的基石。我们建议患者行膀胱镜检查、部分膀胱切除术,并在常规膀胱镜检查和影像学检查的基础上定期随访。它们的罕见性解释了为什么目前没有关于治疗和监测的建议。然而,他们的恶性复发和转移的风险需要定期和长期的随访。结论:膀胱副神经节瘤是一种罕见的肿瘤。治疗应以部分膀胱切除术为基础,并定期随访。
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引用次数: 0
Acute Pulmonary Embolism with Multiple Septic Emboli and Pulmonary Infarcts in an IV Drug Abuser with Right-Sided Endocarditis: A Case Report
Pub Date : 2023-01-02 DOI: 10.59657/2837-8172.brs.23.007
Anup Regmi, Nirmal Prasad Neupane, Aishath Naura, Kritisha Rajlawot
This case report describes the imaging findings of septic pulmonary embolism (SPE) in a 30-year-old male with a history of intravenous drug abuse for one year. The patient initially presented with high grade fever, shortness of breath, and cough in the emergency department of our institution. The patient was evaluated by chest X-ray, blood cultures, echocardiography, and CT pulmonary angiography which confirmed the diagnosis of SPE, and the causative organism was confirmed to be Staphylococcus aureus. In this case report, we discuss the Chest X-ray findings, and characteristic CT imaging findings of SPE and describe the role of different imaging modalities in the timely diagnosis and management of this highly fatal condition.
本病例报告描述了一名30岁男性静脉注射药物滥用史一年的脓毒性肺栓塞(SPE)的影像学表现。患者最初在我院急诊科表现为高热、呼吸急促和咳嗽。经胸片、血培养、超声心动图、CT肺血管造影检查,确诊为SPE,病原菌为金黄色葡萄球菌。在本病例报告中,我们讨论了SPE的胸部x线表现和特征性CT成像表现,并描述了不同的成像方式在及时诊断和治疗这种高度致命疾病中的作用。
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引用次数: 0
Placenta Percreta with Bladder Invasion: Case Report 完全性胎盘伴膀胱侵犯1例
Pub Date : 2023-01-02 DOI: 10.59657/2837-8172.brs.23.003
Mariam Mahtate, A. Slaoui, Soukaina Cherradi, N. Zeraidi, A. Lakhdar, A. Kharbach, Aziz Baydada
Background: Placenta previa with bladder invasion is an uncommon and serious pathology, involving the maternal prognosis. However, as the rate of cesareans has increased, the disease has become more common. Case presentation: We present the case of placenta previa percreta in 34 weeks of amenorrhea, gravida 2 para 1, with a history of a single caesarean section 5 years prior. Initially admitted for threat of premature delivery, we found a totally covering placenta previa with accretization sign and suspicion of bladder invasion. Abdomino pelvic MRI confirmed the diagnosis of placenta previa percreta. During monitoring, the patient presented an acute fetal distress requiring an emergency fetal extraction. She underwent a caesarean section for fetal rescue followed by a total hysterectomy requiring the removing of the anterior part of the bladder. Conclusion: With a rising rate of cesarean sections, the risk of placenta accreta spectrum is increasing as well. Obstetricians and clinicians should be vigilant in prenatal diagnosis, especially if the risk factors are present. Multidisciplinary approach for preoperative, intraoperative and postoperative management can significantly improve maternal and fetal prognosis.
背景:前置胎盘合并膀胱侵犯是一种罕见且严重的病理,影响母体预后。然而,随着剖宫产率的增加,这种疾病变得越来越普遍。病例介绍:我们报告一例完全性前置胎盘的病例在34周闭经,妊娠2第1段,与单一剖宫产史5年前。最初因早产的威胁而入院,我们发现一个完全覆盖的前置胎盘,有增生征象和膀胱侵犯的怀疑。腹盆腔MRI证实为percrevia前置胎盘。在监测期间,患者出现急性胎儿窘迫,需要紧急取出胎儿。她接受了剖腹产抢救胎儿,随后进行了全子宫切除术,切除了膀胱前部。结论:随着剖宫产率的上升,增胎性胎盘谱的风险也在增加。产科医生和临床医生应警惕产前诊断,特别是如果危险因素存在。术前、术中、术后多学科综合管理可显著改善母婴预后。
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引用次数: 0
Clinical Presentation and Management of Primary Mycotic Aortic Aneurysms: A Single Center Experience and Review of the Literature 原发性真菌性主动脉瘤的临床表现和治疗:单中心经验和文献回顾
Pub Date : 2023-01-02 DOI: 10.59657/2837-8172.brs.23.005
Badreldin Mohamed, S. Taha, L. Navaro, M. Cusso, T. Barakat, S. Babikir, D. Taran, C. Marson, T. Ojimba, D. Mirghani, S. Naqvi, R. Eifell
Background: Primary mycotic aortic aneurysm (PMAA) is a localized dilation of the aortic wall caused by direct spread of bacteria via the bloodstream to the aortic wall and subsequent development of an aneurysm. The term mycotic aortic aneurysm was first used to describe a patient with four aortic aneurysms which have a mushroom-like appearance, and the term has since been used. Aim: To conduct a literature review and to report a series of cases of infra-renal mycotic aortic aneurysms, their presentation and subsequent outcome and management. Methods: Information was gathered retrospectively from medical records for patients who were over the age of 18 and who had presented with PMAAs at Cumberland infirmary o from April 2016 to July 2022. Results: A total of six patients were assessed in our study, mean age was 57-88 years. Presenting complains were: Back pain (n=2), abdominal pain (n=1), fever (n=4), collapsed (n=2), confusion (n=1) and other clinical presentations were leg pain, feeling unwell and malaise each reported in one patient each. Potential risk factors for PMAA identified were malignancy (n=2), diabetes mellitus (n=2), chronic kidney disease (n=2), immunosuppressive medication (n=2) and alcohol misuse (n=1). Potential sources of infection were retroperitoneal inflammation (n=1), pyelonephritis (n=1), retroperitoneal /psoas infection (n=2), duodenitis (n=1), systemic sepsis (n=1). Management can be surgical intervention such as Endovascular aortic repair (EVAR) (n=2), or axillo-bifemoral bypass (n=2) all of them had post-operative antibiotics or only antibiotics (n=3), however two patients of them died. Conclusion: PMAAs are rare but they have high risk of morbidity and mortality. The diagnosis is challenging but CT A-abdomen and pelvis remains valuable for diagnosis. Surgery, either bypass or EVAR with antibiotics, is a cornerstone for management, however other alternatives can be considered.
背景:原发性真菌性主动脉瘤(PMAA)是一种由细菌通过血流直接传播到主动脉壁并随后发展成动脉瘤引起的局部主动脉壁扩张。霉菌性主动脉瘤一词最初用于描述有四个呈蘑菇样外观的主动脉瘤的患者,并且该术语已被使用。目的:对肾下真菌性主动脉瘤的临床表现、预后及治疗进行文献回顾和报道。方法:回顾性收集2016年4月至2022年7月在Cumberland医院就诊的18岁以上PMAAs患者的病历资料。结果:本研究共纳入6例患者,平均年龄57 ~ 88岁。主诉为:背部疼痛(n=2)、腹痛(n=1)、发热(n=4)、虚脱(n=2)、精神错乱(n=1),其他临床表现为腿部疼痛、感觉不适和不适,各有1例。PMAA的潜在危险因素为恶性肿瘤(n=2)、糖尿病(n=2)、慢性肾病(n=2)、免疫抑制药物(n=2)和酒精滥用(n=1)。潜在感染源为腹膜后炎症(n=1)、肾盂肾炎(n=1)、腹膜后/腰肌感染(n=2)、十二指肠炎(n=1)、全身性败血症(n=1)。治疗可采取手术干预,如血管内主动脉修复术(EVAR) (n=2)或腋双侧搭桥术(n=2),所有患者术后均使用抗生素或仅使用抗生素(n=3),但其中2例死亡。结论:PMAAs虽少见,但有较高的发病率和死亡率。诊断是具有挑战性的,但CT a -腹部和骨盆仍然是有价值的诊断。手术,无论是搭桥手术还是使用抗生素的EVAR,都是治疗的基础,但也可以考虑其他选择。
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引用次数: 0
Epilepsy and dementia, a bidirectional relationship? 癫痫和痴呆是双向关系吗?
Pub Date : 2023-01-01 DOI: 10.5455/ijmrcr.172-1652269967
Roukya Benkhadra, Sophie Dupont
Introduction: Epilepsy is one of the most common brain conditions, which affects over 70 million people worldwide, with a higher risk for people over the age of 70. In the other hand, dementia prevalence is up to 7% of individuals above the age of 65 years, and concerns 55 million people worldwide. Several studies were conducted to pursue causal relationship or bidirectional connection between those two pathologies and one of the latest systemic reviews gathering a numerous studies about this subject was published in 2017. By reviewing the most relevant articles in the literature we aimed to clarify the interconnection between epilepsy and dementia: coincidence due to the highest incidence in the elderly, or bidirectional relationship? We also focused our research on the newest studies about the possible impact of anti-epileptic drugs to improve dementia and vice versa. Methods: Due to the large numbers of articles about epilepsy and dementia, we collected twenty-three studies and reviews from 2014 to 2021 that focused on the relationship between those two pathologies, also some latest publications, especially epidemiological ones, concerning epilepsy and dementia. Results: Dementia is a heterogeneous syndrome that can be caused by numerous neurological and medical conditions. Epilepsy is more frequent in the elderly and is significantly higher in elderly patients with dementia than in elderly patients without dementia, whatever the type of dementia (AD, Lewy Body dementia, FTD,…). Numerous studies show that the high incidence of both diseases is not a coincidence of ageing and shared risk factors (i.e cerebrovascular events) and that the two diseases share common pathophysiological mechanisms. In the future, antiseizure approaches would complement and potentially enhance other strategies for treating AD, including that targeting disease protein aggregation.
癫痫是最常见的脑部疾病之一,全世界有7000多万人受其影响,70岁以上人群的风险更高。另一方面,65岁以上人群中痴呆症患病率高达7%,全球有5500万人患有痴呆症。研究人员进行了几项研究,以寻求这两种疾病之间的因果关系或双向联系,其中一项最新的系统综述收集了有关该主题的众多研究,于2017年发表。通过回顾文献中最相关的文章,我们旨在澄清癫痫和痴呆之间的联系:由于老年人发病率最高而巧合,还是双向关系?我们还将研究重点放在抗癫痫药物对改善痴呆的可能影响的最新研究上,反之亦然。方法:由于有关癫痫和痴呆的文献比较多,我们收集了2014 - 2021年关于癫痫和痴呆关系的23篇研究和综述,以及一些有关癫痫和痴呆的最新文献,特别是流行病学文献。结果:痴呆是一种异质性综合征,可由许多神经和医学条件引起。癫痫在老年人中更常见,老年痴呆患者的发病率明显高于无痴呆的老年患者,无论是哪种类型的痴呆(阿尔茨海默氏症、路易体痴呆、FTD等)。大量研究表明,这两种疾病的高发病率并非衰老和共同危险因素(即脑血管事件)的巧合,这两种疾病具有共同的病理生理机制。在未来,抗癫痫方法将补充并潜在地增强治疗AD的其他策略,包括靶向疾病蛋白质聚集的策略。
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引用次数: 0
USING THE MODIFIED CLAVIEN GARDING SYSTEM TO CLASSIFY COMPLICATIONS OF BIPOLAR TURP 应用改良的克拉文分级系统对双相障碍并发症进行分类
Pub Date : 2023-01-01 DOI: 10.5455/ijmrcr.172-1664801097
Anurag Dubey, Shivendra Tiwari, P. Patel, Avinash P. S. Thakur
introduction: TURP is considered gold standard treatment for BPH. TURP was first introduced in 1929 by Maximilian Stern. Complications in TURP are less but not absolute. Modified Clavien Dindo Grading System is well-established classification for post-operative complications. Objective of this study is to assess complications of BIPOLAR TURP by using the modified Clavien grading system. Objective: To assess the evaluation of complications after bipolar transurethral resection of prostate using the Modified Clavien grading system. Materials And Methods: 110 BIPOLAR TURP performed between April 2019 and March 2021 at Meenakshi mission hospital Madurai Tamilnadu India were reviewed retrospectively. All patients with various complications were graded using Modified Clavien grading system in 5 grades. Results: 110 cases were enrolled in our study out of them 21 (19.9%) patients developed complications there was no mortality. Out of 21; 11 (52.4%) grade I, 5 (23.8%) grade II, 2 (9.5%) grade IIIa, 1 ( 4.8%) grade IIIb, 1 (4.8%) in each grade IVa and IVb. Conclusion: Modified Clavien Grading System is an easy and feasible classification system for postoperative complications. In spite of various shortcomings, it is very useful to grade end-urological procedure BIPOLAR TURP short-term complications.
TURP被认为是治疗前列腺增生的金标准。TURP于1929年由Maximilian Stern首次提出。TURP的并发症较少,但不是绝对的。改良Clavien Dindo分级系统是一种完善的术后并发症分级系统。本研究的目的是使用改良的Clavien分级系统来评估双相TURP的并发症。目的:探讨应用改良Clavien分级系统评价双极经尿道前列腺切除术术后并发症的价值。材料与方法:回顾性分析2019年4月至2021年3月在印度泰米尔纳德邦Meenakshi教会医院实施的110例双极TURP。所有患者的各种并发症采用改良Clavien分级系统分为5级。结果:110例患者入组,其中21例(19.9%)出现并发症,无死亡。21人中;I级11人(52.4%),II级5人(23.8%),IIIa级2人(9.5%),IIIb级1人(4.8%),IVa和IVb级各1人(4.8%)。结论:改良Clavien分级系统是一种简便可行的术后并发症分级系统。尽管有各种各样的缺点,它是非常有用的分级终末泌尿外科手术双极TURP短期并发症。
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引用次数: 0
Recent Trends And Seroprevalence Of Transfusion Transmitted Diseases Among Blood Donors In Western India 印度西部献血者输血传播疾病的最新趋势和血清流行率
Pub Date : 2023-01-01 DOI: 10.5455/ijmrcr.172-1662094058
D. Jose, D. Kale, Deepesh Chhablani, No author No author, D. Ingale, Dr.Chandrashekar Gore, D. Kumar
Abstract Introduction: Assessments of Transfusion Transmitted Diseases (TTDs) are essential for evaluating the safety of blood transfusion as well as monitoring the efficacy of current screening procedures. It also helps in formulating lifelong planning to upgrade our public health and to stop the spread of TTDs in general public. Materials and Methods: Our objective was to find out the recent trends and seroprevalence of TTDs in voluntary blood donors at a tertiary care hospital in western part of India. A total 4117 donors are included in our study from January to December 2019. The blood samples were tested for Human Immunodeficiency Virus I and II, Hepatitis B and C virus, Syphilis and Malaria. Results: Out of 4117 donors, a total of 39 (0.95 %) donors were positive for Transfusion Transmitted Diseases, out of which 23 (0.56%), 7(0.17%) and 9 (0.22%) donors were positive for HBV, HIV and HCV respectively. Conclusion: The most substantial part of every blood donation is finding out accurate blood donors who are at very low risk for Transfusion Transmitted Diseases and is achieved through efficient counseling and inclusion of more sophisticated techniques for screening to reduce the transmission during the window period. Key words : Transfusion Transmitted Diseases, blood donors, seroprevalence, Window period
摘要简介:输血传播疾病(TTDs)的评估是评价输血安全性和监测现行筛查程序有效性的必要条件。它还有助于制定终身规划,以提高我们的公共卫生水平,并阻止TTDs在公众中传播。材料和方法:我们的目的是了解印度西部一家三级医院自愿献血者中TTDs的最新趋势和血清患病率。2019年1月至12月,共有4117名捐赠者参与了我们的研究。对血样进行了人类免疫缺陷病毒I型和II型、乙型和丙型肝炎病毒、梅毒和疟疾的检测。结果:4117名献血者输血传播疾病阳性39人(0.95%),其中HBV阳性23人(0.56%),HIV阳性7人(0.17%),HCV阳性9人(0.22%)。结论:每次献血最重要的部分是找到输血传播疾病风险极低的准确献血者,并通过有效的咨询和更复杂的筛查技术来实现,以减少窗口期的传播。关键词:输血传播疾病,献血者,血清阳性率,窗口期
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引用次数: 0
Evaluating the efficacy of combination therapy of Pregabalin plus Nortriptyline in the management of PHN patients: A randomized controlled study 评估普瑞巴林联合去甲替林治疗PHN患者的疗效:一项随机对照研究
Pub Date : 2023-01-01 DOI: 10.5455/ijmrcr.172-1669175453
Swati Das, A. Saxena, G. Chilkoti, Anshul Singh, Sargam Goel
Background: Post Herpetic Neuralgia (PHN) is chronic neuropathic pain. It is a complication of herpes zoster and negatively impacts the patient’s quality of life and physical, occupational, social and psychosocial abilities due to unceasing pain. As pain management remains the cornerstone in treating such patients, this study was undertaken to determine the efficacy of fixed-dose combination therapy of Pregabalin plus Nortriptyline in PHN. Methods: The study, which was a follow-up, randomised, single-blind, controlled study, included a total of 40 patients who had chronic pain for at least 12 weeks with a Numeric rating scale (NRS) score of 5/10 or above. Group A (n=20) received pregabalin 75 mg plus nortriptyline 10 mg, and group B (n=20) received pregabalin 75 mg for a total of 12 weeks. Pain intensity and severity (using NRS and Global Perceived Effect), pain interference with sleep (using Numeric Rating Scale-Sleep (NRS-Sleep) and Pain Detect Questionnaire (PDQ)), pain quality (using Neuropathic Pain Symptom Inventory (NPSI)), and quality of life (QoL) (using Short Form-12 (SF-12) questionnaire) at the end of the first, second, fourth, eighth and twelfth week were measured. Results: Significant (p <0.05) decline in Numeric rating scale (NRS) scores, NRS sleep and NPSI scores in group A along with significant (p <0.05) improvement in PDQ, GPE and QoL scores, when compared to group B. Conclusion: The combination of pregabalin plus nortriptyline therapy has better patient outcomes in PHN as compared to pregabalin monotherapy.
背景:疱疹后神经痛是一种慢性神经性疼痛。它是带状疱疹的一种并发症,由于持续的疼痛,对患者的生活质量和身体、职业、社会和心理社会能力产生负面影响。由于疼痛管理仍然是治疗此类患者的基础,本研究旨在确定普瑞巴林加去甲替林固定剂量联合治疗PHN的疗效。方法:该研究是一项随访、随机、单盲、对照研究,共纳入40例慢性疼痛至少12周,数值评定量表(NRS)评分为5/10或以上的患者。A组(n=20)给予普瑞巴林75 mg +去甲替林10 mg, B组(n=20)给予普瑞巴林75 mg,疗程共12周。在第一、第二、第四、第八和第十二周结束时测量疼痛强度和严重程度(使用NRS和Global Perceived Effect)、疼痛干扰睡眠(使用数字评定量表-睡眠(NRS- sleep)和疼痛检测问卷(PDQ))、疼痛质量(使用神经性疼痛症状量表(NPSI))和生活质量(使用SF-12短表问卷)。结果:与b组相比,A组的数值评定量表(NRS)评分、NRS睡眠评分和NPSI评分均显著(p <0.05)下降,PDQ、GPE和QoL评分均显著(p <0.05)改善。结论:普瑞巴林联合去甲替林治疗PHN患者的预后优于普瑞巴林单药治疗。
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引用次数: 0
DOUBLE EDGED SWORD- MUCORMYCOIS IN COVID 19 PATIENTS 双刃剑——covid - 19患者中的毛霉菌
Pub Date : 2023-01-01 DOI: 10.5455/ijmrcr.172-1671011456
Prathyusha Thummalagunta, Pragna Kakera, Lokabhinay Naidu
INTRODUCTION : There is an increasing risk of mucormycosis in the post Covid patients , especially in the second wave of the pandemic, there has been a tremendous rise of mucormycosis in covid 19 cases, therby increasing the mortality and morbidity. There are many risk factors contributing to mucor among which diabetes mellitus is seen as an independant and most common risk factor. AIMS AND OBJECTIVES : To study the clinical manifestations, treatment ,mortality and mortality of mucormycosis in covid 19 . MATERIALS AND METHODS : This is an observational study carried out between April 2021 to june 2021. This study observes the clinical manifestations and CT findings ,treatment and outcomes in 25 patients of mucormycosis. OBSERVATION : This study included a total 25 patients of which 21(84%) are male and 4(16%) are female. The age of the patients varied between 25 -60 years with 49 years being the mean age group. Out of 25 members ,20 have diabetes, 1 has hypertension, 3 have hypothyroidism, 6 are smokers, 2 have coronary artery disease and are alcoholics. 24 underwent FESS & debridement and were treated with Amphotericin B and posaconazole. And 23 out of 25 used steroids. 2 of the 25 members died of severe mucor out of which 1 died before surgery and 1 after surgery CONCLUSION : In this study it has been observed that the early diagnosis and treatment of mucormycosis with better control of diabetes leads to improvement of mortality and morbidity in these patients.
摘要:新冠肺炎后患者发生毛霉菌病的风险不断增加,特别是在第二波大流行中,新冠肺炎患者的毛霉菌病发病率大幅上升,从而增加了死亡率和发病率。引起毛霉的危险因素很多,其中糖尿病被认为是一个独立的、最常见的危险因素。目的和目的:研究2019冠状病毒病毛霉病的临床表现、治疗、死亡率和死亡率。材料和方法:这是一项观察性研究,于2021年4月至2021年6月进行。本文对25例毛霉病的临床表现、CT表现、治疗及预后进行了观察。观察:本研究共纳入25例患者,其中男性21例(84%),女性4例(16%)。患者年龄在25 -60岁之间,平均年龄49岁。在25名成员中,20人患有糖尿病,1人患有高血压,3人患有甲状腺功能减退症,6人吸烟,2人患有冠状动脉疾病和酗酒。24例行FESS和清创,并用两性霉素B和泊沙康唑治疗。25人中有23人使用类固醇。25例患者中2例死于严重毛霉病,其中1例死于术前,1例死于术后。结论:本研究发现,对毛霉病进行早期诊断和治疗,并对糖尿病进行较好的控制,可降低毛霉病患者的死亡率和发病率。
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引用次数: 0
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International Journal of Medical Reviews and Case Reports
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