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Gender-based linguistic differences in letters of recommendation for rhinology fellowship over time: A dual-institutional follow-up study using natural language processing and deep learning 鼻科学奖学金推荐信中的性别语言差异:使用自然语言处理和深度学习的双机构跟踪研究。
IF 7.2 2区 医学 Q1 OTORHINOLARYNGOLOGY Pub Date : 2024-07-16 DOI: 10.1002/alr.23411
Vikram Vasan BA, Christopher P. Cheng AB, Shaun Edalati BS, Shreya Mandloi BS, David K. Lerner MD, Anthony Del Signore MD, Madeleine Schaberg MD, Satish Govindaraj MD, Mindy Rabinowitz MD, Gurston Nyquist MD, Alfred Marc Iloreta MD

Key points

  • This follow-up dual-institutional and longitudinal study further evaluated for underlying gender biases in LORs for rhinology fellowship.
  • Explicit and implicit linguistic gender bias was found, heavily favoring male applicants
要点:这项后续的双机构纵向研究进一步评估了鼻科学研究金申请者的LOR中是否存在潜在的性别偏见。研究发现,显性和隐性语言性别偏见严重偏向男性申请人。
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引用次数: 0
There is no sinus without “us”: A randomized controlled study assessing the efficacy of shared decision-making in the surgical management of chronic rhinosinusitis 没有 "我们 "就没有鼻窦:一项随机对照研究,评估共同决策在慢性鼻窦炎手术治疗中的疗效。
IF 7.2 2区 医学 Q1 OTORHINOLARYNGOLOGY Pub Date : 2024-07-16 DOI: 10.1002/alr.23407
Vivienne Li BA, Andrew Yousef MD, Divya Prajapati MD, Michael Oca BS, Leslie Gomez FNP, Adam S. DeConde MD, Carol H. Yan MD

Key points

  • CRS patients exhibit little decision conflict in their choice of pursuing surgery.
  • Standard counseling alone appears to suffice once patients express an interest in surgery.
  • Decision aids may increase patient knowledge and improve postoperative care understanding.
要点:CRS患者在选择手术时很少出现决策冲突。一旦患者表示对手术感兴趣,仅靠标准咨询似乎就足够了。决策辅助工具可增加患者对手术的了解,并提高对术后护理的理解。
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引用次数: 0
A methodological pipeline for the preclinical evaluation of novel topical agents for the treatment of CRS 用于治疗 CRS 的新型外用制剂临床前评估的方法流水线。
IF 7.2 2区 医学 Q1 OTORHINOLARYNGOLOGY Pub Date : 2024-07-16 DOI: 10.1002/alr.23418
Samuel J. M. Hale MB, ChB, BMedSc(Hons), Christian A. Lux PhD, James E. Willoughby, Arne Koefoed BSc, David Broderick PhD, Kristi Biswas PhD, Raymond Kim MB, ChB, PhD, Brett Wagner Mackenzie PhD, Richard G. Douglas MD

Key points

  • Novel topical therapeutics require extensive pre-clinical testing to assess efficacy and safety.
  • Antibiofilm or immunosuppressant agents can utilize ex vivo models to measure ciliotoxicity.
  • Agents that are found to be effective and non-toxic ex vivo warrant further investigation in vivo.
要点:新型局部治疗药物需要进行广泛的临床前测试,以评估疗效和安全性。抗生物膜或免疫抑制剂可利用体外模型来衡量纤毛毒性。在体外发现有效且无毒的制剂应在体内进行进一步研究。
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引用次数: 0
V-Y advancement flap for the repair of localized cutaneous defects following nasal closure in severe hereditary hemorrhagic telangiectasia. V-Y 推进皮瓣用于修复重度遗传性出血性毛细血管扩张症鼻腔闭合后的局部皮肤缺损。
IF 7.2 2区 医学 Q1 OTORHINOLARYNGOLOGY Pub Date : 2024-07-16 DOI: 10.1002/alr.23415
Guled M Jama, Simon Gane
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引用次数: 0
American Rhinologic Society Expert Practice Statement: Indications and Recommendations for Septoplasty in Children 美国鼻科学会专家实践声明:儿童鼻中隔成形术的适应症和建议。
IF 7.2 2区 医学 Q1 OTORHINOLARYNGOLOGY Pub Date : 2024-07-12 DOI: 10.1002/alr.23397
Austin S. Rose MD, MBA, Chadi A. Makary MD, Zachary M. Soler MD, Adam J. Kimple MD, PhD, Aaron N. Pearlman MD, Uma S. Ramaswamy MD, Michael Setzen MD, David A. Gudis MD

The goal of this American Rhinologic Society Expert Practice Statement (EPS) is to provide recommendations and guidance through evidence-based consensus statements regarding pediatric septoplasty. This EPS was developed following the previously published methodology and approval process. The topics of interest included appropriate indications, safety and efficacy, timing, relevant quality of life instruments, and surgical techniques. Following a modified Delphi approach, six statements were developed, five of which reached consensus and one that did not. These statements and accompanying evidence are summarized along with an assessment of future needs.

本《美国鼻科学会专家实践声明》(EPS)旨在通过基于证据的共识声明,为小儿鼻中隔成形术提供建议和指导。本 EPS 是按照之前公布的方法和审批程序制定的。关注的主题包括适当的适应症、安全性和有效性、时机、相关的生活质量工具以及手术技术。经过改良的德尔菲法(Delphi approach),共制定了六项声明,其中五项达成共识,一项未达成共识。本报告对这些声明和相关证据进行了总结,并对未来需求进行了评估。
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引用次数: 0
Multi-institutional validation of an AI-based sinus CT analytic platform with olfactory assessments 基于人工智能的鼻窦 CT 分析平台与嗅觉评估的多机构验证。
IF 7.2 2区 医学 Q1 OTORHINOLARYNGOLOGY Pub Date : 2024-07-12 DOI: 10.1002/alr.23410
Conner J. Massey MD, Stephen M. Humphries PhD, Jess C. Mace MPH, Timothy L. Smith MD, MPH, Zachary M. Soler MD, MSc, Vijay R. Ramakrishnan MD

Key points

  • AI-based CT sinus analysis may have advantages over visual based systems, for example, Lund–Mackay score.

  • Here, we show multi-institutional validation of an AI algorithm using novel OMC classification.

  • Significant, robust correlations are seen between algorithm outputs and clinical outcomes.

要点:与基于视觉的系统(如 Lund-Mackay 评分)相比,基于人工智能的 CT 窦分析可能更具优势。在此,我们展示了使用新型 OMC 分类的人工智能算法的多机构验证。算法输出与临床结果之间存在显著、稳健的相关性。
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引用次数: 0
American Rhinologic Society expert practice statement part 2: Postoperative precautions and management principles following endoscopic skull base surgery 美国鼻科学会专家实践声明第 2 部分:内窥镜颅底手术后的术后注意事项和管理原则。
IF 7.2 2区 医学 Q1 OTORHINOLARYNGOLOGY Pub Date : 2024-07-12 DOI: 10.1002/alr.23406
Jennifer E. Douglas MD, Nithin D. Adappa MD, Garret Choby MD, Corinna G. Levine MD, MPH, Mindy R. Rabinowitz MD, Raj Sindwani MD, Eric W. Wang MD, Bradford A. Woodworth MD, Edward C. Kuan MD, MBA

The goal of this American Rhinologic Society expert practice statement (EPS) is to summarize the best available evidence regarding postoperative precautions for patients following endoscopic skull base surgery for intradural pathology. These topics include the administration of postoperative nasal hygiene; patient mobilization and activity level; the resumption of continuous positive airway pressure in patients with obstructive sleep apnea; and the timing and capacity with which a patient may be subjected to barotrauma, such as air travel postoperatively. This EPS was developed following the recommended methodology and approval process as previously outlined. Given the diverse practices and limited agreement on the accepted principles regarding postoperative precautions for patients following skull base surgery, this EPS seeks to summarize the existing literature and provide clinically relevant guidance to bring clarity to these differing practice patterns. Following a modified Delphi approach, four statements were developed, all of which reached consensus. Because of the paucity of literature on these topics, these statements represent a summation of the limited literature and the experts’ opinions. These statements and the accompanying evidence are summarized below, along with an assessment of future needs.

本美国鼻科学会专家实践声明(EPS)旨在总结有关硬膜内病变内窥镜颅底手术患者术后预防措施的最佳可用证据。这些主题包括术后鼻腔卫生的管理;患者的活动和活动量;阻塞性睡眠呼吸暂停患者恢复持续气道正压的情况;以及患者可能遭受气压创伤(如术后乘飞机旅行)的时间和能力。本 EPS 是按照之前概述的推荐方法和审批流程制定的。鉴于颅底手术后患者术后预防措施的实践多种多样,且公认原则的一致性有限,本 EPS 试图总结现有文献并提供临床相关指导,以澄清这些不同的实践模式。经过改良的德尔菲法(Delphi approach),共制定了四项声明,所有声明均已达成共识。由于有关这些主题的文献很少,这些声明是对有限文献和专家意见的总结。下文概述了这些声明和相关证据,以及对未来需求的评估。
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引用次数: 0
Chitosan-based crosslinking for controlled topical drug release in rhinosinusitis 基于壳聚糖的交联技术用于鼻炎的局部控释药物。
IF 7.2 2区 医学 Q1 OTORHINOLARYNGOLOGY Pub Date : 2024-07-11 DOI: 10.1002/alr.23413
Do-Yeon Cho MD, Dong Jin Lim PhD, Olivia J. Kelly, Daniel Skinner BS, Shaoyan Zhang PhD, Martin P. Jones BS, Jessica Grayson MD, Bradford A. Woodworth MD

Key points

  • Chitosan is a promising drug delivery vector for therapeutics owing to its biocompatibility.
  • Once crosslinked with chitosan, prolonged drug release was noted regardless of hydrophilicity.
  • Hydrophilic drugs may require different strategies to obtain a sustained release profile.
要点:壳聚糖具有生物相容性,是一种很有前景的药物输送载体。与壳聚糖交联后,无论亲水性如何,药物释放时间都会延长。亲水性药物可能需要不同的策略才能获得持续释放特性。
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引用次数: 0
Letter to the editor regarding “An eosinophil peroxidase activity assay predicts acute exacerbations in post-operative chronic rhinosinusitis” 致编辑的信,内容涉及 "嗜酸性粒细胞过氧化物酶活性测定可预测术后慢性鼻炎急性加重"。
IF 7.2 2区 医学 Q1 OTORHINOLARYNGOLOGY Pub Date : 2024-07-10 DOI: 10.1002/alr.23408
Sanjeev Yadav MBBS, MS, DNB
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引用次数: 0
30° anteriorly tilted CT for visualizing the drainage pathway of the frontal sinus 用于观察额窦引流路径的 30° 前倾 CT。
IF 7.2 2区 医学 Q1 OTORHINOLARYNGOLOGY Pub Date : 2024-07-10 DOI: 10.1002/alr.23404
Tomotaka Hemmi MD, PhD, Kazuhiro Nomura MD, PhD, Mitsuru Sugawara MD, PhD, Ryoukichi Ikeda MD, PhD

Key points

  • The optimal tilt for anteriorly tilted coronal CT was examined.
  • A 30° anteriorly tilted coronal CT best visualized the frontal sinus drainage pathway.
要点研究了前倾冠状 CT 的最佳倾斜度。前倾 30° 的冠状 CT 最能显示额窦引流路径。
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International Forum of Allergy & Rhinology
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