Recently, a male patient, presented to multiple medical specialties that eventually led to development of diarrhea and weight loss followed by eventual review by a gastroenterologist and a specific diagnosis of Whipple’s disease, a systemic disorder first described more than a century ago, but only recently recognized to be caused by Tropheryma whipplei . In this report, an updated review of this apparently very rare clinical disorder was done, including studies permitting a specific diagnosis of this disorder along with exclusion of other intestinal mucosal disorders that may potentially mimic Whipple’s disease.
{"title":"Whipple’s Disease and Its Intestinal Mucosal Mimics","authors":"Hugh James Freeman, James Gray","doi":"10.12691/ijcd-11-1-7","DOIUrl":"https://doi.org/10.12691/ijcd-11-1-7","url":null,"abstract":"Recently, a male patient, presented to multiple medical specialties that eventually led to development of diarrhea and weight loss followed by eventual review by a gastroenterologist and a specific diagnosis of Whipple’s disease, a systemic disorder first described more than a century ago, but only recently recognized to be caused by Tropheryma whipplei . In this report, an updated review of this apparently very rare clinical disorder was done, including studies permitting a specific diagnosis of this disorder along with exclusion of other intestinal mucosal disorders that may potentially mimic Whipple’s disease.","PeriodicalId":13927,"journal":{"name":"International Journal of Celiac Disease","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79960415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Characteristic of Coeliac Disease in Adult Sudanese Patients and Gender Difference at Ibn Sena Specialized Hospital, Khartoum State, Sudan","authors":"Dalia Alemam, Wamda Alemam, Hala Abu El Hassan","doi":"10.12691/ijcd-11-1-3","DOIUrl":"https://doi.org/10.12691/ijcd-11-1-3","url":null,"abstract":"","PeriodicalId":13927,"journal":{"name":"International Journal of Celiac Disease","volume":"65 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91124408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Adenocarcinoma in the Small Intestine in Celiac Disease over more than 30-years","authors":"Hugh J. Freeman","doi":"10.12691/ijcd-11-1-4","DOIUrl":"https://doi.org/10.12691/ijcd-11-1-4","url":null,"abstract":"","PeriodicalId":13927,"journal":{"name":"International Journal of Celiac Disease","volume":"97 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73241090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
With an average of 1/200 affected people around the world, celiac disease still lacks a cure. Here a concept of a viral therapy with certain design degrees of freedom is suggested to the scientific community with the hope that a well experienced and equipped research team is able to endeavour such project. Also, safety concerns of the viral therapy about escape mutations and trophism are covered. These ideas can be extended to any autoimmune disease with an etiological alteration of the memory T-cells, paving the way to safer alternatives to the immunological reboot.
{"title":"Celivir: A Viral Therapy for the Autoimmune Celiac Disease","authors":"Jose Crespo-Barrios","doi":"10.12691/ijcd-11-1-8","DOIUrl":"https://doi.org/10.12691/ijcd-11-1-8","url":null,"abstract":"With an average of 1/200 affected people around the world, celiac disease still lacks a cure. Here a concept of a viral therapy with certain design degrees of freedom is suggested to the scientific community with the hope that a well experienced and equipped research team is able to endeavour such project. Also, safety concerns of the viral therapy about escape mutations and trophism are covered. These ideas can be extended to any autoimmune disease with an etiological alteration of the memory T-cells, paving the way to safer alternatives to the immunological reboot.","PeriodicalId":13927,"journal":{"name":"International Journal of Celiac Disease","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73400344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gluten free diet is the only proven treatment for celiac disease. This study aims to investigate the dietary challenges of adults with celiac disease. A web-based survey was completed by adult patients diagnosed with CD across Saudi Arabia. The survey included questions exploring demographics, the challenges in their diet as well as questions about their behaviour of eating out. Most of the participants were females and more than half are living in Riyadh. Furthermore, 65.7% were diagnosed by bowel biopsy and 72.3% were diagnosed for more than 1 year, 95.8% are following a gluten-free diet but 51.8% are not under a nutritional program 57.1% are not following up with a dietitian. Furthermore, 96.4% of participants considered restaurants are problems in providing gluten-free food and 86.1% are avoiding restaurants. This study concluded that adults with celiac disease are following GFD without follow -up with health care providers (HCPs), this can lead to increase many complications of this disease. Moreover, increasing the awareness about CD and GFD is important among patients, HCPs and society including, families and friends and people dealing with food business.
{"title":"Dietary Challenges in Adults with Celiac Disease in Saudi Arabia","authors":"Sehad N. Alarifi, Maha H. Alhussain","doi":"10.12691/ijcd-11-1-2","DOIUrl":"https://doi.org/10.12691/ijcd-11-1-2","url":null,"abstract":"Gluten free diet is the only proven treatment for celiac disease. This study aims to investigate the dietary challenges of adults with celiac disease. A web-based survey was completed by adult patients diagnosed with CD across Saudi Arabia. The survey included questions exploring demographics, the challenges in their diet as well as questions about their behaviour of eating out. Most of the participants were females and more than half are living in Riyadh. Furthermore, 65.7% were diagnosed by bowel biopsy and 72.3% were diagnosed for more than 1 year, 95.8% are following a gluten-free diet but 51.8% are not under a nutritional program 57.1% are not following up with a dietitian. Furthermore, 96.4% of participants considered restaurants are problems in providing gluten-free food and 86.1% are avoiding restaurants. This study concluded that adults with celiac disease are following GFD without follow -up with health care providers (HCPs), this can lead to increase many complications of this disease. Moreover, increasing the awareness about CD and GFD is important among patients, HCPs and society including, families and friends and people dealing with food business.","PeriodicalId":13927,"journal":{"name":"International Journal of Celiac Disease","volume":"341 2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78131209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aaron Lerner, J. Freire de Carvalho, Thiago Ferreira da Silva, Carina Benzvi, Maria Fernanda Leal dos Santos Ribeiro, Moti Haimi
A relationship between autism and autoimmunity is well known and various autoimmune diseases were associated with the autistic spectrum. Relapsing polychondritis is a rare autoimmune disease manifested mainly in adults. Following is the first case presentation of a girl presented with relapsing polychondritis who was on the autistic spectrum. Several mechanisms can be envisioned to connect those two diseases
{"title":"Relapsing Polychondritis in a Child with Autism: Rare within Rare 1st Case Described","authors":"Aaron Lerner, J. Freire de Carvalho, Thiago Ferreira da Silva, Carina Benzvi, Maria Fernanda Leal dos Santos Ribeiro, Moti Haimi","doi":"10.12691/ijcd-11-1-6","DOIUrl":"https://doi.org/10.12691/ijcd-11-1-6","url":null,"abstract":"A relationship between autism and autoimmunity is well known and various autoimmune diseases were associated with the autistic spectrum. Relapsing polychondritis is a rare autoimmune disease manifested mainly in adults. Following is the first case presentation of a girl presented with relapsing polychondritis who was on the autistic spectrum. Several mechanisms can be envisioned to connect those two diseases","PeriodicalId":13927,"journal":{"name":"International Journal of Celiac Disease","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90541268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gluten Exposure Can Trigger a Silent Autoimmune Disorder in Celiac Disease: Five Case Reports","authors":"Farahnaz Safaei, Amir Sadeghi, Pardis Ketabi Moghadam, Peyman Taheri, Mehran Taheri","doi":"10.12691/ijcd-11-1-5","DOIUrl":"https://doi.org/10.12691/ijcd-11-1-5","url":null,"abstract":"","PeriodicalId":13927,"journal":{"name":"International Journal of Celiac Disease","volume":"357 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76507109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aaron Lerner, J. Freire de Carvalho, Maria Fernanda Leal dos Santos Ribeiro, Carina Benzvi
{"title":"Kefir and Kombucha for Rheumatic Disease: A Systematic Review","authors":"Aaron Lerner, J. Freire de Carvalho, Maria Fernanda Leal dos Santos Ribeiro, Carina Benzvi","doi":"10.12691/ijcd-11-1-1","DOIUrl":"https://doi.org/10.12691/ijcd-11-1-1","url":null,"abstract":"","PeriodicalId":13927,"journal":{"name":"International Journal of Celiac Disease","volume":"82 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89648398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sur M Lucia, Floca Emanuela, Lupan Iulia, Sur Genel, Samaşca Gabriel
{"title":"Clinical Scenario for Medical Students in Adult Multiple Autoimmune Diseases","authors":"Sur M Lucia, Floca Emanuela, Lupan Iulia, Sur Genel, Samaşca Gabriel","doi":"10.12691/ijcd-10-1-8","DOIUrl":"https://doi.org/10.12691/ijcd-10-1-8","url":null,"abstract":"","PeriodicalId":13927,"journal":{"name":"International Journal of Celiac Disease","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74523489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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