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Three-Dimensional Analysis of Occlusal Plane Changes After Clear Aligner Therapy: A Retrospective Study. 清除矫正器治疗后咬合平面变化的三维分析:一项回顾性研究。
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-29 eCollection Date: 2025-01-01 DOI: 10.1155/ijod/8893287
Domenico Ciavarella, Carlotta Fanelli, Mauro Lorusso, Carmela Suriano, Beatrice Iachini, Michele Laurenziello, Laura Guida, Lucio Lo Russo, Nicola Sgaramella, Rosa Esposito, Michele Tepedino

Objective: The purpose of the present study was to evaluate: (i) occlusal plane (OP) changes after clear aligner therapy (CAT) and (ii) whether such changes correlate with the patient's facial divergence.

Materials and methods: Three-dimensional models of 118 patients (49 males and 59 females; mean ± standard deviation age 22.3 ± 3.4 years) treated with clear aligners were analysed retrospectively. Using CAD-CAM software, it was possible to define three planes: the reference palatine plane (PP), the OP and the reference vertical maxillary plane. The PP and OP meet mesially, identifying an angle (α) in the sagittal view. The intersection of the occlusal and vertical maxillary planes creates two angles in the frontal view: an angle (β) for the right side and an angle (γ) for the left side. Using Autodesk Fusion 360, the angles were investigated before treatment (T0) and after treatment (T1) to calculate the change for each angle Δ(T1-T0). Subsequently, lateral cephalograms were analysed and five measurements were made.

Results: One-way analysis of variance (ANOVA), showed a significant difference between hyperdivergent and hypodivergent patients for Δα and Δβ. The post hoc Tukey test showed the following differences: Δα was 3.81° greater in hyperdivergent patients compared with hypodivergent patients, and Δβ was 1.69° greater in hyperdivergent patients compared with hypodivergent patients.

Conclusion: Treatment with aligners did not lead to a clinically significant change in the OP. However, when dividing the sample into groups based on craniofacial divergence, OP orientation change differed significantly between the three groups.

Clinical significance: According to the present study, aligners may be a useful therapeutic option for hyperdivergent patients and a less favourable option for hypodivergent patients and patients with occlusal asymmetries, both structural and functional, who may need particular treatment approaches and diagnostic evaluations.

目的:本研究的目的是评估:(i)清除对准器治疗(CAT)后咬合平面(OP)的变化以及(ii)这种变化是否与患者面部散度相关。材料与方法:回顾性分析118例患者(男49例,女59例,平均±标准差年龄22.3±3.4岁)三维模型。使用CAD-CAM软件,可以定义三个平面:参考腭平面(PP), OP和参考上颌垂直平面。PP和OP在矢状面相接,形成一个角度(α)。咬合面和垂直上颌面相交在正面视图中产生两个角度:右侧的角度(β)和左侧的角度(γ)。使用Autodesk Fusion 360检查治疗前(T0)和治疗后(T1)的角度,计算每个角度的变化Δ(T1-T0)。随后,对侧位脑电图进行了分析,并进行了五次测量。结果:单因素方差分析(ANOVA)显示Δα和Δβ的高发散和低发散患者之间存在显著差异。事后Tukey检验显示以下差异:超发散患者Δα比低发散患者大3.81°,超发散患者Δβ比低发散患者大1.69°。结论:矫形器治疗并未导致OP发生临床意义上的改变,但根据颅面散度分组时,三组间OP取向变化差异显著。临床意义:根据目前的研究,矫正器可能是一种有用的治疗选择,对于高发散患者和低发散患者和有结构和功能不对称的患者,可能需要特殊的治疗方法和诊断评估。
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引用次数: 0
The Health and Lives of Dental Professionals in the Brazilian Public Health System During the COVID-19 Pandemic: An Observational Study in the City of Manaus, Amazonas. 2019冠状病毒病大流行期间巴西公共卫生系统牙科专业人员的健康和生活:亚马逊州马瑙斯市的一项观察性研究
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-28 eCollection Date: 2025-01-01 DOI: 10.1155/ijod/1549178
Priscilla Farias Naiff, Shirley Maria de Araújo Passos, Tania França

Objective: To investigate the implications of the COVID-19 pandemic on the lives of dentists in the municipal health network of Manaus.

Methods: A cross-sectional, descriptive, and exploratory study with a quantitative and qualitative approach. Between April and July 2022, an online questionnaire with closed and open questions was applied to dentists. The study included 81 professionals. The collected data were stored in a Microsoft Excel 2007 spreadsheet, generated by Google forms. For categorical data, absolute and relative frequencies were obtained. Content analysis, aided by Atlas ti software, Version 22, was used for textual analysis.

Results: The COVID-19 pandemic represented a constant source of stress and fear for dentists, negatively affecting their mental health.

Conclusions: In view of the above, the Unified Health System (SUS) needs to implement effective measures to protect and promote the mental health of its workers, such as offering specialized psychological support, promoting awareness campaigns on mental health risks, and creating support groups for professionals.

目的:了解2019冠状病毒病大流行对马瑙斯市卫生网络牙医生活的影响。方法:采用定量和定性方法进行横断面、描述性和探索性研究。在2022年4月至7月期间,对牙医进行了一份包含封闭式和开放式问题的在线问卷调查。这项研究包括81名专业人士。收集的数据存储在Microsoft Excel 2007电子表格中,由谷歌表单生成。对于分类数据,获得绝对频率和相对频率。文本分析采用内容分析,由Atlas ti软件辅助,版本22。结果:COVID-19大流行是牙医压力和恐惧的持续来源,对他们的心理健康产生了负面影响。结论:综上所述,统一卫生系统(SUS)需要实施有效的措施来保护和促进其工作人员的心理健康,如提供专门的心理支持,开展心理健康风险的宣传活动,并为专业人员建立支持小组。
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引用次数: 0
Comparative Evaluation of Locally Applied Chlorhexidine 1% Gel and Citrus sinensis Peel Extract Gel as an Adjunct to Nonsurgical Periodontal Therapy in Localized Periodontitis Treatment: A Clinico-Microbiological Study. 局部应用1%氯己定凝胶与柑橘皮提取物凝胶非手术牙周治疗辅助治疗局部牙周炎的比较评价:临床微生物学研究。
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-28 eCollection Date: 2025-01-01 DOI: 10.1155/ijod/2038398
Ishika Sarkar, Pritish Chandra Pal, Swet Nisha, Debika Karmakar, S R Savan, Dhanraj Budhai, Amjad Abu Hasna

Background: Periodontal disease is polymicrobial in nature and to control the infection we need to target the inflammatory component. Nonsurgical periodontal therapy is used for mechanical debridement. Use of agents along with nonsurgical periodontal therapy is gaining momentum. Locally delivered agents like antibiotics and herbal products are used in nonsurgical and surgical periodontal therapy. Phytotherapy offers antioxidant, antimicrobial action and has less chances of drug resistance.

Objective: This study design compared locally delivered chlorhexidine (CHX) 1% gel and Citrus sinensis peel extract (CSPE) gel in the management localized periodontitis as an adjuvant treatment to scaling and root planing (SRP).

Material and method: Forty-six subjects diagnosed with Grade II/III localized periodontitis were randomly assigned into two groups. After thorough SRP, CSPE gel placement was done in the test group and 1% CHX gel in the control group. Clinical parameters measured were probing pocket depth (PPD), clinical attachment level (CAL) and microbiological analysis (bacterial culture from pocket sample) was done prior to SRP and at 60 days.

Results: Both the 1% CHX and CSPE gel provide comparable outcome (p ≥ 0.05) in improvement of PPD, CAL and bacterial colony count. Statistically significant results were obtained in terms of PPD; p = 0.044 (test group) and p = 0037 (control group). CAL showed statistically significant results in test group with p = 0.044. Inter group and Intra group comparison of plaque index showed no statistical difference. Colony forming units (CFU) between the two groups (p = 0.001) was found statistically significant.

Conclusion: Locally delivered herbal CSPE gel can be an effective, economical,and antibacterial gel as an adjunctive treatment of periodontitis.

背景:牙周病本质上是多微生物的,为了控制感染,我们需要针对炎症成分。非手术牙周治疗用于机械清创。与非手术牙周治疗一起使用药物的势头正在增强。局部提供的药物如抗生素和草药产品用于非手术和手术牙周治疗。植物疗法具有抗氧化、抗菌作用,耐药几率较小。目的:本研究设计比较1%氯己定凝胶(CHX)和柑桔皮提取物凝胶(CSPE)在局部牙周炎治疗中的辅助治疗效果。材料与方法:将46例诊断为II/III级局限性牙周炎的患者随机分为两组。经彻底SRP后,实验组放置CSPE凝胶,对照组放置1% CHX凝胶。临床参数测量为探针口袋深度(PPD)、临床附着水平(CAL)和微生物分析(口袋样本细菌培养)在SRP前和60天完成。结果:1% CHX和CSPE凝胶在改善PPD、CAL和细菌菌落计数方面具有可比性(p≥0.05)。在PPD方面取得了具有统计学意义的结果;P = 0.044(试验组),P = 0037(对照组)。试验组CAL结果有统计学意义,p = 0.044。组间、组内斑块指数比较,差异无统计学意义。两组间菌落形成单位(CFU)差异有统计学意义(p = 0.001)。结论:局部给药的中药CSPE凝胶是一种有效、经济、抗菌的辅助治疗牙周炎的凝胶。
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引用次数: 0
Efficacy of Periodontal Surgery on Subgingival Periodontopathogen Levels in Periodontitis Patients: A Randomized Clinical Trial. 牙周手术对牙周炎患者龈下牙周病原水平的影响:一项随机临床试验。
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-26 eCollection Date: 2025-01-01 DOI: 10.1155/ijod/4419048
Cansu Bayram, Ece Açıkgöz-Alparslan

Objectives: This study evaluates the changes in subgingival periodontopathogens following access flap surgery (AFS) in Stage III Grade B periodontitis patients.

Materials and methods: This randomized clinical split-mouth study included 20 systemically healthy periodontitis patients. Participants' right and left quadrants were randomly assigned to the control (nonsurgery) or test (AFS) group. Quantities of subgingival periodontopathogens (Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia) and periodontal measurements (gingival index [GI], plaque index [PI], bleeding on probing [BOP], probing depth [PD], and clinical attachment level [CAL]) were evaluated before and 4 weeks after surgery. Quantitative polymerase chain reaction was utilized for detecting and quantifying periodontopathogens.

Results: A significant reduction in periodontopathogens was observed in the test group, while levels increased in the control group (p  < 0.05). A significant difference was noted between the groups in changes in the quantities of periodontopathogens (p  < 0.05). The reduction in periodontal parameters was significantly greater in the test group 1-month post-AFS (p  < 0.05). Positive correlations were observed between decreases in P. gingivalis levels and reductions in T. denticola and T. forsythia (p  < 0.05).

Conclusions: AFS effectively reduces subgingival periodontopathogens and enhances periodontal health in the early healing phase. It demonstrates significant benefits for patients with advanced periodontitis and deep residual pockets.

Clinical relevance: AFS is an effective treatment option for managing deep residual pockets, as it promotes periodontal health and significantly reduces bacterial burden during the critical early healing phase. These results are particularly valuable for clinicians aiming to prevent disease progression, thereby enhancing patient care and treatment outcomes. Trial Registration: ClinicalTrials.gov identifier: NCT06684288.

目的:本研究评估III期B级牙周炎患者行通道皮瓣手术(AFS)后龈下牙周病原的变化。材料和方法:本随机临床裂口研究纳入了20例全身健康的牙周炎患者。参与者的左右象限被随机分配到对照组(非手术)或试验组(AFS)。术前和术后4周评估龈下牙周病原(牙龈卟啉单胞菌、牙密螺旋体和连缀Tannerella forsythia)数量和牙周测量(牙龈指数[GI]、菌斑指数[PI]、探诊出血[BOP]、探诊深度[PD]、临床附着水平[CAL])。采用定量聚合酶链反应对牙周病病原菌进行检测和定量。结果:实验组牙周病菌明显减少,对照组牙周病菌明显增多(p < 0.05)。两组牙周病致病菌数量变化差异有统计学意义(p < 0.05)。afs后1个月,试验组牙周参数下降幅度更大(p < 0.05)。牙龈假单胞菌水平的下降与齿形假单胞菌和连翘假单胞菌的下降呈显著正相关(p < 0.05)。结论:AFS能有效减少牙龈下的牙周病致病菌,促进牙周健康。它对晚期牙周炎和深层残余口袋的患者有显著的益处。临床意义:AFS是一种有效的治疗方案,用于管理深层残留口袋,因为它可以促进牙周健康,并在关键的早期愈合阶段显著减少细菌负担。这些结果对旨在预防疾病进展的临床医生特别有价值,从而提高患者的护理和治疗效果。试验注册:ClinicalTrials.gov标识符:NCT06684288。
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引用次数: 0
Lingual Concavities in Posterior Mandible: Retrospective Morphometric Analysis in Relation to Gender and Tooth Loss. 后下颌舌凹:与性别和牙齿缺失相关的回顾性形态计量学分析。
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-22 eCollection Date: 2025-01-01 DOI: 10.1155/ijod/5209739
Khulood Ali Al-Taezi, Wei Chen, Lin Liu, Zhankun Cai, Belal O M Muhaisen, Chunbo Tang

Objectives: To analyze the posterior mandible bone ridge shape in relation to gender and tooth loss. Focusing on the accompanied changes and variations in lingual concavities.

Methods: 406 cone-beam computed tomography (CBCT) images with dentulous and edentulous 1st and/or 2nd molars (206 females and 200 males, aged ≥20) were examined. Mandibular morphology was classified into U type (undercut), P type (parallel), and C type (convex). The study examined the ridge morphology and dimensions. Lingual concavities angle, area, and the concavity position were measured/reported.

Results: U type bone shape was the most common bone shape 64.1%, then P type was 24.8%, while C type was 11.2 %. U ridge was more frequent in 2nd molar compared to the 1st molar regions (p = 0.04), while C type was statistically related to long extraction time (p = 0.001). Many bone ridge measurements were higher in males (p < 0.05). Other significant differences in measurements were found at 36, 37, 46, and 47 dentate and missing sites (p < 0.05). Lingual concavities were larger in males (p < 0.001) and relatively larger at 2nd molar dentulous ridges; 37 (p = 0.02). Also, they were more statistically frequent at the level of mandibular canal (MC) or above (p = 0.0001).

Conclusion: The U type ridge was the most common in the studied population, occurring more often in the second molars region. Bone ridge and lingual concavities dimensions were varied by gender, tooth loss, and specific tooth. Lingual concavities were significantly related to MC level.

目的:分析后下颌骨脊形态与性别、牙缺失的关系。重点关注舌凹的变化和变化。方法:对406张无牙和无牙第一和/或第二磨牙的锥形束计算机断层扫描(CBCT)图像进行检查,其中女性206张,男性200张,年龄≥20岁。下颌形态分为U型(下凹)、P型(平行)和C型(凸)。该研究检查了脊的形态和尺寸。测量/报告舌凹的角度、面积和凹陷位置。结果:U型骨型占64.1%,P型占24.8%,C型占11.2%。第二磨牙U型牙嵴较第一磨牙多见(p = 0.04),而C型牙嵴与拔牙时间较长有统计学意义(p = 0.001)。许多骨脊测量值在男性中较高(p < 0.05)。在36、37、46和47个齿状和缺失位点的测量结果也存在显著差异(p < 0.05)。男性舌凹较大(p < 0.001),第2磨牙齿脊相对较大;37 (p = 0.02)。在下颌管(MC)及以上水平(p = 0.0001)发生率更高。结论:U型牙脊在研究人群中最为常见,多见于第二磨牙区。骨脊和舌凹的大小因性别、牙齿脱落和特定牙齿而异。舌凹与MC水平显著相关。
{"title":"Lingual Concavities in Posterior Mandible: Retrospective Morphometric Analysis in Relation to Gender and Tooth Loss.","authors":"Khulood Ali Al-Taezi, Wei Chen, Lin Liu, Zhankun Cai, Belal O M Muhaisen, Chunbo Tang","doi":"10.1155/ijod/5209739","DOIUrl":"10.1155/ijod/5209739","url":null,"abstract":"<p><strong>Objectives: </strong>To analyze the posterior mandible bone ridge shape in relation to gender and tooth loss. Focusing on the accompanied changes and variations in lingual concavities.</p><p><strong>Methods: </strong>406 cone-beam computed tomography (CBCT) images with dentulous and edentulous 1st and/or 2nd molars (206 females and 200 males, aged ≥20) were examined. Mandibular morphology was classified into U type (undercut), P type (parallel), and C type (convex). The study examined the ridge morphology and dimensions. Lingual concavities angle, area, and the concavity position were measured/reported.</p><p><strong>Results: </strong>U type bone shape was the most common bone shape 64.1%, then P type was 24.8%, while C type was 11.2 %. U ridge was more frequent in 2nd molar compared to the 1st molar regions (<i>p</i> = 0.04), while C type was statistically related to long extraction time (<i>p</i> = 0.001). Many bone ridge measurements were higher in males (<i>p</i> < 0.05). Other significant differences in measurements were found at 36, 37, 46, and 47 dentate and missing sites (<i>p</i> < 0.05). Lingual concavities were larger in males (<i>p</i> < 0.001) and relatively larger at 2nd molar dentulous ridges; 37 (<i>p</i> = 0.02). Also, they were more statistically frequent at the level of mandibular canal (MC) or above (<i>p</i> = 0.0001).</p><p><strong>Conclusion: </strong>The U type ridge was the most common in the studied population, occurring more often in the second molars region. Bone ridge and lingual concavities dimensions were varied by gender, tooth loss, and specific tooth. Lingual concavities were significantly related to MC level.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2025 ","pages":"5209739"},"PeriodicalIF":2.2,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12752905/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145877894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Shear Bond Strength of Silane-Containing Universal Adhesives in Repairing Aged 3D-Printed Provisional Restorations With Flowable Composite: An In Vitro Study. 含硅烷通用胶粘剂在可流动复合材料修复老化3d打印临时修复体中的剪切结合强度:体外研究
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-22 eCollection Date: 2025-01-01 DOI: 10.1155/ijod/5245327
Wisarut Prawatvatchara, Awutsadaporn Katheng, Paweena Kongkon, Santisuk Sombun, Piangkwan Saiprasert, Nawaporn Jittapiromsak

Background: The repairability of provisional restorative materials affects the duration of the provisional treatment phase. This study evaluated the effects of various silane (Si)-containing universal adhesives on the shear bond strength (SBS) of aged three-dimensional (3D)-printed provisional restorative materials.

Methods: Seventy SBS specimens (20 mm diameter × 15 mm height) and 10 specimens for energy-dispersive X-ray (EDX) analysis (5 mm diameter × 3 mm height) were fabricated. All SBS specimens underwent thermocycling in artificial saliva at 5- 55 °C, with 60 s dwell time, using a thermocycler (SD Mechatronik, Germany). The SBS specimens were randomly divided into seven groups (n = 10 per group) on the basis of the repair method: C group (control), S group (Single Bond 2), SU group (Scotchbond Universal), SUP group (Scotchbond Universal Plus), CUQ group (CLEARFIL TRI-S BOND Universal Quick), GPB group (G-Premio Bond), and Si + S group (Silane Ultradent + Single Bond 2). The SBS test was performed using a universal testing machine (Instron, ElectroPulsTM E1000, England). Failure modes were analyzed for all debonding surfaces. Data was analyzed using one-way analysis of variance (ANOVA) and Tukey's HSD test (p < 0.05).

Results: The highest SBS was observed in the Si + S group (21.06 ± 1.47 MPa), followed by SUP (19.43 ± 1.45 MPa), CUQ (16.14 ± 1.54 MPa), SU (15.71 ± 1.40 MPa), GPB (12.93 ± 1.56 MPa), S (12.59 ± 1.64 MPa), and C (8.20 ± 1.49 MPa). However, no significant difference in the SBS was observed between the Si + S and SUP groups. Additionally, there was no significant difference in SBS between S and GPB. Failure mode analysis revealed a correlation between the type of failure pattern and the SBS results.

Conclusion: The SUP group, a silane-containing universal adhesive, demonstrated high SBS comparable with the separate application of Si, suggesting it as a viable alternative in provisional material repair.

背景:临时修复材料的可修复性影响临时治疗阶段的持续时间。本研究评估了不同含硅烷(Si)的通用胶粘剂对老化三维(3D)打印临时修复材料剪切结合强度(SBS)的影响。方法:制作SBS标本70份(直径20 mm ×高15 mm)和能量色散x射线(EDX)分析标本10份(直径5 mm ×高3 mm)。所有SBS标本使用热循环器(SD Mechatronik,德国)在5- 55°C的人工唾液中进行热循环,停留时间为60 s。根据修复方法将SBS试件随机分为7组,每组10只:C组(对照)、S组(Single Bond 2)、SU组(Scotchbond Universal)、SUP组(Scotchbond Universal Plus)、CUQ组(CLEARFIL TRI-S Bond Universal Quick)、GPB组(G-Premio Bond)、Si + S组(硅烷超聚物+ Single Bond 2)。SBS测试使用通用试验机(Instron, ElectroPulsTM E1000, England)进行。分析了所有剥离表面的失效模式。数据分析采用单因素方差分析(ANOVA)和Tukey’s HSD检验(p < 0.05)。结果:Si + S组的SBS最高(21.06±1.47 MPa),其次为SUP(19.43±1.45 MPa)、CUQ(16.14±1.54 MPa)、SU(15.71±1.40 MPa)、GPB(12.93±1.56 MPa)、S(12.59±1.64 MPa)、C(8.20±1.49 MPa)。然而,在Si + S组和SUP组之间没有观察到SBS的显著差异。此外,SBS在S和GPB之间没有显著差异。失效模式分析揭示了失效模式类型与SBS结果之间的相关性。结论:SUP组是一种含硅烷的通用胶粘剂,具有与单独应用Si相当的高SBS,提示其作为临时材料修复的可行选择。
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引用次数: 0
Evaluation of Morphology and Location of Greater Palatine Foramen (GPF) in Different Sagittal Facial Types: A CBCT Study in an Iranian Adult Population. 不同矢状面型腭大孔(GPF)形态和位置的评估:伊朗成年人群的CBCT研究。
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-22 eCollection Date: 2025-01-01 DOI: 10.1155/ijod/6654674
Fatemeh Akbarizadeh, Shabnam Ajami, Kiarash Fereidouni, Mohsen Khaksari

Aim: The greater palatine foramen (GPF) transmits the greater palatine neurovascular bundle, and its position and shape directly affect palatal anesthesia, palatal surgery, and graft harvesting. This study aimed to evaluate variations in the location and morphology of the GPF across different sagittal maxillary growth patterns in an Iranian adult sample.

Methods: Sixty cone beam computed tomography (CBCT) scans were analyzed (20 per Sella-Nasion-A (SNA) angle: deficient, normal, excessive). GPF shape, location relative to the molar teeth, its position with respect to adjacent structures (including distances to the alveolar ridge, mid-palatal suture, contralateral GPF, and incisive foramen [IF]), and the angle between the mid-palatal suture, IF midpoint, and GPF midpoint were assessed and compared among the three sagittal maxillary growth patterns.

Results: The GPF-IF distance differed significantly between sagittal groups (right: p = 0.004; left: p = 0.005), being shorter in the deficient maxillary group. The distribution of the GPF position relative to the molar teeth also differed significantly between groups (both sides: p  < 0.001). Other morphometric parameters showed no significant differences (Table 1).

Conclusion: In this Iranian adult sample sagittal maxillary growth pattern is associated with variations in GPF-IF distance and its anteroposterior position relative to molars; these should be considered during palatal anesthesia and surgical planning. Further clinical correlation is warranted.

目的:腭大孔(GPF)传递腭大神经血管束,其位置和形态直接影响腭麻醉、腭手术和移植收获。本研究旨在评估伊朗成人样本中不同矢状面上颌生长模式GPF的位置和形态变化。方法:对60例锥形束ct (CBCT)扫描结果进行分析(SNA角度:不足、正常、过度各20例)。评估和比较三种矢状上颌生长模式中GPF的形状、相对于磨牙的位置、相对于邻近结构的位置(包括到牙槽嵴的距离、中腭缝线、对侧GPF和锐孔[IF]),以及中腭缝线、IF中点和GPF中点之间的角度。结果:矢状面组间GPF-IF距离差异显著(右:p = 0.004;左:p = 0.005),上颌缺牙组GPF-IF距离较短。GPF相对于磨牙位置的分布在两组之间也有显著差异(两边p < 0.001)。其他形态计量参数无显著差异(表1)。结论:在这个伊朗成人样本中,上颌矢状面生长模式与GPF-IF距离及其相对于磨牙的前后位置的变化有关;在腭麻醉和手术计划时应考虑这些因素。进一步的临床相关性是必要的。
{"title":"Evaluation of Morphology and Location of Greater Palatine Foramen (GPF) in Different Sagittal Facial Types: A CBCT Study in an Iranian Adult Population.","authors":"Fatemeh Akbarizadeh, Shabnam Ajami, Kiarash Fereidouni, Mohsen Khaksari","doi":"10.1155/ijod/6654674","DOIUrl":"10.1155/ijod/6654674","url":null,"abstract":"<p><strong>Aim: </strong>The greater palatine foramen (GPF) transmits the greater palatine neurovascular bundle, and its position and shape directly affect palatal anesthesia, palatal surgery, and graft harvesting. This study aimed to evaluate variations in the location and morphology of the GPF across different sagittal maxillary growth patterns in an Iranian adult sample.</p><p><strong>Methods: </strong>Sixty cone beam computed tomography (CBCT) scans were analyzed (20 per Sella-Nasion-A (SNA) angle: deficient, normal, excessive). GPF shape, location relative to the molar teeth, its position with respect to adjacent structures (including distances to the alveolar ridge, mid-palatal suture, contralateral GPF, and incisive foramen [IF]), and the angle between the mid-palatal suture, IF midpoint, and GPF midpoint were assessed and compared among the three sagittal maxillary growth patterns.</p><p><strong>Results: </strong>The GPF-IF distance differed significantly between sagittal groups (right: <i>p</i> = 0.004; left: <i>p</i> = 0.005), being shorter in the deficient maxillary group. The distribution of the GPF position relative to the molar teeth also differed significantly between groups (both sides: <i>p</i>  < 0.001). Other morphometric parameters showed no significant differences (Table 1).</p><p><strong>Conclusion: </strong>In this Iranian adult sample sagittal maxillary growth pattern is associated with variations in GPF-IF distance and its anteroposterior position relative to molars; these should be considered during palatal anesthesia and surgical planning. Further clinical correlation is warranted.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2025 ","pages":"6654674"},"PeriodicalIF":2.2,"publicationDate":"2025-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12752903/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145878336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plant and Fungal Polysaccharides in Periodontitis Treatment: Diverse Mechanisms and Therapeutic Roles. 植物和真菌多糖在牙周炎治疗中的作用:不同的机制和治疗作用。
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-18 eCollection Date: 2025-01-01 DOI: 10.1155/ijod/7284794
Fan Wu, Shangyan Li, Jiawen Chen, Yuqin Shen, Amjad Abu Hasna

Background: Periodontitis is a chronic immune-mediated inflammatory disease characterized by the progressive degradation of periodontal tissues. Conventional therapies, including anti-inflammatory agents and antibiotics, are limited by systemic adverse effects and increased microbial resistance, highlighting the need for safer, multi-targeted treatments.

Objective: This review systematically evaluates the therapeutic potential of plant- and fungal-derived polysaccharides in periodontitis treatment. It focuses on their multifaceted biological activities, including anti-inflammatory, antioxidant, antimicrobial, and osteo-regenerative effects, and elucidates key molecular mechanisms, such as nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), mitogen-activated protein kinase (MAPK), Wnt/β-catenin, and BMP-2/Smad signaling pathways. Additionally, it identifies current research gaps and proposes strategies to facilitate the translational development of polysaccharide-based therapies.

Materials and methods: A systematic literature search was performed across PubMed, Scopus, Web of Science, and Google Scholar databases using a combination of Medical Subject Heading (MeSH) terms and keywords, including "periodontitis," "plant polysaccharides," "fungal polysaccharides," "inflammatory factors," and "bone regeneration." A total of 104 studies were included after screening for relevance to the therapeutic roles and molecular mechanisms of plant- and fungal-derived polysaccharides in periodontitis. The dataset encompassed both in vitro and in vivo investigations, and narrative synthesis was employed to integrate findings owing to the substantial heterogeneity in study designs, endpoints, and methodological approaches.

Conclusion: Plant- and fungal-derived polysaccharides have substantial potential as adjunct or alternative therapies for the treatment of periodontitis. Their multifunctional activities, including modulation of inflammation, inhibition of pathogenic biofilms, and promotion of periodontal tissue regeneration, are mediated through complex multi-pathway interactions. Clinical translation remains limited by structural heterogeneity, a lack of standardized preparation protocols, and insufficient in vivo validation. Future research should prioritize elucidating structure-activity relationships, optimizing extraction and formulation methods, and conducting well-designed clinical trials. Integrating evidence from 104 studies, this review underscores the anti-inflammatory, antimicrobial, and osteo-regenerative effects of these polysaccharides and emphasizes their importance in future clinical applications.

背景:牙周炎是一种慢性免疫介导的炎症性疾病,其特征是牙周组织的进行性退化。包括抗炎药和抗生素在内的常规疗法受到全身不良反应和微生物耐药性增加的限制,因此需要更安全的多靶点治疗。目的:系统评价植物源性多糖和真菌源性多糖在牙周炎治疗中的治疗潜力。它侧重于其多方面的生物活性,包括抗炎、抗氧化、抗菌和骨再生作用,并阐明了关键的分子机制,如活化B细胞的核因子κB轻链增强子(NF-κB)、丝裂原活化蛋白激酶(MAPK)、Wnt/β-catenin和BMP-2/Smad信号通路。此外,它还确定了当前的研究差距,并提出了促进基于多糖的疗法的转化开发的策略。材料和方法:在PubMed、Scopus、Web of Science和谷歌Scholar数据库中进行了系统的文献检索,使用医学主题标题(MeSH)术语和关键词,包括“牙周炎”、“植物多糖”、“真菌多糖”、“炎症因子”和“骨再生”。筛选后共纳入104项研究,以了解植物和真菌来源的多糖在牙周炎中的治疗作用和分子机制。该数据集包括体外和体内研究,由于研究设计、终点和方法方法存在很大的异质性,因此采用叙事综合来整合研究结果。结论:植物和真菌来源的多糖作为治疗牙周炎的辅助或替代疗法具有很大的潜力。它们的多种功能,包括调节炎症、抑制致病生物膜和促进牙周组织再生,是通过复杂的多途径相互作用介导的。临床翻译仍然受到结构异质性、缺乏标准化制备方案和体内验证不足的限制。未来的研究应重点阐明构效关系,优化提取和配方方法,并进行精心设计的临床试验。综合104项研究的证据,本综述强调了这些多糖的抗炎、抗菌和骨再生作用,并强调了它们在未来临床应用中的重要性。
{"title":"Plant and Fungal Polysaccharides in Periodontitis Treatment: Diverse Mechanisms and Therapeutic Roles.","authors":"Fan Wu, Shangyan Li, Jiawen Chen, Yuqin Shen, Amjad Abu Hasna","doi":"10.1155/ijod/7284794","DOIUrl":"10.1155/ijod/7284794","url":null,"abstract":"<p><strong>Background: </strong>Periodontitis is a chronic immune-mediated inflammatory disease characterized by the progressive degradation of periodontal tissues. Conventional therapies, including anti-inflammatory agents and antibiotics, are limited by systemic adverse effects and increased microbial resistance, highlighting the need for safer, multi-targeted treatments.</p><p><strong>Objective: </strong>This review systematically evaluates the therapeutic potential of plant- and fungal-derived polysaccharides in periodontitis treatment. It focuses on their multifaceted biological activities, including anti-inflammatory, antioxidant, antimicrobial, and osteo-regenerative effects, and elucidates key molecular mechanisms, such as nuclear factor kappa-light-chain-enhancer of activated B cells (NF-<i>κ</i>B), mitogen-activated protein kinase (MAPK), Wnt/<i>β</i>-catenin, and BMP-2/Smad signaling pathways. Additionally, it identifies current research gaps and proposes strategies to facilitate the translational development of polysaccharide-based therapies.</p><p><strong>Materials and methods: </strong>A systematic literature search was performed across PubMed, Scopus, Web of Science, and Google Scholar databases using a combination of Medical Subject Heading (MeSH) terms and keywords, including \"periodontitis,\" \"plant polysaccharides,\" \"fungal polysaccharides,\" \"inflammatory factors,\" and \"bone regeneration.\" A total of 104 studies were included after screening for relevance to the therapeutic roles and molecular mechanisms of plant- and fungal-derived polysaccharides in periodontitis. The dataset encompassed both in vitro and in vivo investigations, and narrative synthesis was employed to integrate findings owing to the substantial heterogeneity in study designs, endpoints, and methodological approaches.</p><p><strong>Conclusion: </strong>Plant- and fungal-derived polysaccharides have substantial potential as adjunct or alternative therapies for the treatment of periodontitis. Their multifunctional activities, including modulation of inflammation, inhibition of pathogenic biofilms, and promotion of periodontal tissue regeneration, are mediated through complex multi-pathway interactions. Clinical translation remains limited by structural heterogeneity, a lack of standardized preparation protocols, and insufficient in vivo validation. Future research should prioritize elucidating structure-activity relationships, optimizing extraction and formulation methods, and conducting well-designed clinical trials. Integrating evidence from 104 studies, this review underscores the anti-inflammatory, antimicrobial, and osteo-regenerative effects of these polysaccharides and emphasizes their importance in future clinical applications.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2025 ","pages":"7284794"},"PeriodicalIF":2.2,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12752907/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145878307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation of Bond Strength and Dentinal Tubule Penetration Evaluation of Four Different Endodontic Sealers: AH Plus, MTA Fillapex, Endoseal MTA, and Endoseal TCS (Maruchi): An In Vitro Study. 四种不同的牙髓密封剂:AH +、MTA Fillapex、Endoseal MTA和Endoseal TCS的结合强度与牙本质小管渗透评估的相关性(Maruchi):一项体外研究。
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-17 eCollection Date: 2025-01-01 DOI: 10.1155/ijod/9972346
Arezoo Mirzaei Sadeghloo, Seyedali Seyedmajidi, Akam Saeidi, Elham Mahmoudi

Background: The sealer's penetration into dentinal tubules creates a physical barrier that entombs any remaining bacteria and increases the surface contact with the root canal walls. This study aimed to evaluate the dentinal tubule penetration and push-out bond strength of four sealers and to assess the correlation between penetration depth and bond strength.

Methods: In this in vitro study, 40 human single-rooted anterior teeth were divided into four groups based on the sealer type and obturated using the single cone technique. Three slices of 1 ± 0.1 mm thickness were then prepared from each tooth at three regions-coronal, middle, and apical thirds-perpendicular to the longitudinal axis of the root. The depth and percentage of sealer penetration into the dentinal tubules were measured using confocal laser scanning microscopy (CLSM) on the prepared slices. To assess the bond strength of the sealers to dentin walls, a push-out bond strength test was performed using a universal testing machine. Data were analyzed using SPSS software through ANOVA, Tukey post hoc and Pearson's correlation tests. A p-value of <0.05 was considered statistically significant.

Results: Statistically significant differences were observed in the extent and percentage of penetration, and the push-out bond strength of the studied sealers (p  < 0.001 for all). Additionally, a significant correlation was found between bond strength and penetration percentage for AH Plus (p = 0.046 and r = 0.366), between bond strength and both penetration extent (p = 0.013 and r = 0.448) and penetration percentage (p = 0.001 and r = 0.572) for Endoseal MTA, and between bond strength and penetration extent for Endoseal TCS (p = 0.001 and r = 0.57).

Conclusion: Calcium silicate-based sealers (Endoseal MTA and Endoseal TCS) achieved the greatest penetration, whereas AH Plus demonstrated the highest bond strength. The positive correlations observed suggest that dentinal tubule penetration may contribute to stronger bonding for specific sealers.

背景:封口剂渗透到牙本质小管中会形成一个物理屏障,将任何残留的细菌埋藏起来,并增加与根管壁的表面接触。本研究旨在评估四种牙本质小管的渗透和推出结合强度,并评估渗透深度和结合强度之间的相关性。方法:将40颗人单根前牙按封闭器类型分为4组,采用单锥体技术进行封闭。然后在垂直于根的纵轴的三个区域(冠状、中、尖三分之一)分别制备3片厚度为1±0.1 mm的切片。用激光共聚焦扫描显微镜(CLSM)对制备好的牙本质小管片进行深度和百分比的测量。为了评估密封剂与牙本质壁的结合强度,使用万能试验机进行了推出结合强度试验。数据采用SPSS软件进行方差分析、Tukey事后检验和Pearson相关检验。结果的p值:在所研究的密封剂的渗透程度和百分比以及推出粘结强度方面观察到统计学上显著的差异(p < 0.001)。此外,AH Plus的结合强度与穿透率(p = 0.046, r = 0.366)、Endoseal MTA的结合强度与穿透度(p = 0.013, r = 0.448)和穿透率(p = 0.001, r = 0.572)、Endoseal TCS的结合强度与穿透度(p = 0.001, r = 0.57)之间存在显著相关性。结论:硅酸钙基密封剂(Endoseal MTA和Endoseal TCS)具有最大的穿透性,而AH Plus具有最高的结合强度。观察到的正相关性表明,牙本质小管的渗透可能有助于增强特定封口剂的结合。
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引用次数: 0
Knowledge on First Aid Management of Traumatic Dental Injuries Among Primary School Teachers of Dharan, Nepal. 尼泊尔达兰小学教师创伤性牙损伤的急救管理知识。
IF 2.2 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-17 eCollection Date: 2025-01-01 DOI: 10.1155/ijod/6614216
Ashish Shrestha, Tarakant Bhagat, Santosh Kumari Agrawal, Ashma Ojha

Introduction: Majority of the traumatic dental injuries (TDIs) occur at schools. School teachers are the immediate person to come in contact after dental injuries, so it is necessary for them to have knowledge about the first aid management of the injured tooth.

Objective: To determine the knowledge of first aid management of TDIs among primary school teachers of Dharan, Nepal.

Methods: A cross-sectional questionnaire based study was conducted among primary school teachers of Dharan city. A self-administered questionnaire was distributed among 110 school teachers equally from both public (n = 55) and private (n = 55) schools. Descriptive statistics, chi-square test, and logistic regression analysis were used to report the data. The level of significance was set at p  < 0.05.

Results: The mean age of the school teachers participating in the study was 36.38 ± 10.98 years. Majority of them (73.6%) were females. Only few school teachers (23.6%) were informed or trained about dental trauma. The primary source of information was through the internet (57.7%). More than two-third of the school teachers had poor knowledge (85.5%) on first-aid management of TDIs. A statistically significant difference was observed in the primary management of avulsed tooth between teachers of public and private schools (p = 0.007).

Conclusion: The findings of this study concluded that primary school teachers of Dharan city had poor knowledge on first-aid management of TDIs which reflects a need to improve their knowledge on the same.

简介:大多数创伤性牙齿损伤(TDIs)发生在学校。学校教师是牙齿受伤后第一个接触的人,因此他们有必要了解受伤牙齿的急救管理知识。目的:了解尼泊尔达兰地区小学教师对tdi的急救管理知识。方法:采用横断面问卷法对达兰市小学教师进行调查。一份自我管理的问卷在110名公立(n = 55)和私立(n = 55)学校教师中平均分发。采用描述性统计、卡方检验和logistic回归分析对数据进行报道。p < 0.05为显著性水平。结果:参与研究的学校教师平均年龄为36.38±10.98岁。其中以女性居多(73.6%)。只有少数学校教师(23.6%)被告知或接受过有关牙外伤的培训。主要信息来源为互联网(57.7%)。超过三分之二(85.5%)的学校教师对tdi急救管理知识贫乏。公立学校教师与私立学校教师对撕脱牙的初级处理差异有统计学意义(p = 0.007)。结论:达兰市小学教师对tdi急救管理的知识水平较低,需要进一步提高tdi急救管理知识。
{"title":"Knowledge on First Aid Management of Traumatic Dental Injuries Among Primary School Teachers of Dharan, Nepal.","authors":"Ashish Shrestha, Tarakant Bhagat, Santosh Kumari Agrawal, Ashma Ojha","doi":"10.1155/ijod/6614216","DOIUrl":"10.1155/ijod/6614216","url":null,"abstract":"<p><strong>Introduction: </strong>Majority of the traumatic dental injuries (TDIs) occur at schools. School teachers are the immediate person to come in contact after dental injuries, so it is necessary for them to have knowledge about the first aid management of the injured tooth.</p><p><strong>Objective: </strong>To determine the knowledge of first aid management of TDIs among primary school teachers of Dharan, Nepal.</p><p><strong>Methods: </strong>A cross-sectional questionnaire based study was conducted among primary school teachers of Dharan city. A self-administered questionnaire was distributed among 110 school teachers equally from both public (<i>n</i> = 55) and private (<i>n</i> = 55) schools. Descriptive statistics, chi-square test, and logistic regression analysis were used to report the data. The level of significance was set at <i>p</i>  < 0.05.</p><p><strong>Results: </strong>The mean age of the school teachers participating in the study was 36.38 ± 10.98 years. Majority of them (73.6%) were females. Only few school teachers (23.6%) were informed or trained about dental trauma. The primary source of information was through the internet (57.7%). More than two-third of the school teachers had poor knowledge (85.5%) on first-aid management of TDIs. A statistically significant difference was observed in the primary management of avulsed tooth between teachers of public and private schools (<i>p</i> = 0.007).</p><p><strong>Conclusion: </strong>The findings of this study concluded that primary school teachers of Dharan city had poor knowledge on first-aid management of TDIs which reflects a need to improve their knowledge on the same.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2025 ","pages":"6614216"},"PeriodicalIF":2.2,"publicationDate":"2025-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12752895/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145877652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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International Journal of Dentistry
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