Pub Date : 2018-01-09DOI: 10.18311/IJMDS/2018/18909
Radhika Mittal, Rakesh Kumar
Background: Stress is a state of mental or emotional strain or tension resulting from adverse or demanding circumstances. Stress level in all aspects of life is growing at an exponential rate but stress level in students, especially MBBS students is alarming. Objective: To find out the level of stress and relieving methods used by medical students before examination. Material and Methods: Observational, Cross sectional study was conducted on 600 medical students using questionnaire. Responses of the students were recorded on Likert’s scale just after the examination. Data was tabulated and analyzed statistically. Results: The mean age of 600 medical students were 20.1±0.9. 143(23.8%) students always felt stressed, 161(26.8%) often, 211(35.2%) sometimes, 37(6.2%) rarely and 48(8%) never felt stressed before examination. 252(42%) reported that this level of stress did not affect their performance in examination while decrease in performance was reported by 198(33%). 150(25%) said that their performance was improved during examination due to stress. 145(24.2%) felt no anxiety during examination, 432(72%) felt healthy anxiety and 23(3.8%) felt unhealthy anxiety level. Conclusion: Majority of the medical students experiences some level of anxiety during exams and used various coping mechanisms to deal with stress. Although some degree of stress is accepted as a normal part of medical training and can be a motivator for some individuals, not all students find the stress manageable.
{"title":"Exam Stress in MBBS Students and the Methods Used for its Alleviation","authors":"Radhika Mittal, Rakesh Kumar","doi":"10.18311/IJMDS/2018/18909","DOIUrl":"https://doi.org/10.18311/IJMDS/2018/18909","url":null,"abstract":"Background: Stress is a state of mental or emotional strain or tension resulting from adverse or demanding circumstances. Stress level in all aspects of life is growing at an exponential rate but stress level in students, especially MBBS students is alarming. Objective: To find out the level of stress and relieving methods used by medical students before examination. Material and Methods: Observational, Cross sectional study was conducted on 600 medical students using questionnaire. Responses of the students were recorded on Likert’s scale just after the examination. Data was tabulated and analyzed statistically. Results: The mean age of 600 medical students were 20.1±0.9. 143(23.8%) students always felt stressed, 161(26.8%) often, 211(35.2%) sometimes, 37(6.2%) rarely and 48(8%) never felt stressed before examination. 252(42%) reported that this level of stress did not affect their performance in examination while decrease in performance was reported by 198(33%). 150(25%) said that their performance was improved during examination due to stress. 145(24.2%) felt no anxiety during examination, 432(72%) felt healthy anxiety and 23(3.8%) felt unhealthy anxiety level. Conclusion: Majority of the medical students experiences some level of anxiety during exams and used various coping mechanisms to deal with stress. Although some degree of stress is accepted as a normal part of medical training and can be a motivator for some individuals, not all students find the stress manageable.","PeriodicalId":14010,"journal":{"name":"International Journal of Medical and Dental Sciences","volume":"268 1","pages":"1604-1608"},"PeriodicalIF":0.0,"publicationDate":"2018-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79819512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-09DOI: 10.18311/IJMDS/2018/18906
Jatinder Singh, Vaneeta Bhardwar, Anchal Kumra
Background: Exclusive breastfeeding (EBF) is the best nutrition for children during the first six months of life. However EBF remains a challenge. Objective: The aim of the study was to assess Knowledge, Attitude and Practice towards EBF among lactating mothers. Methods: A community based cross-sectional study was conducted among 350 mothers using a structured interviewer-administered questionnaire using 'recall since birth' method. Systematic random sampling was used to select the study participants and descriptive statistics were conducted. Results: Out of 350 lactating women, maximum women belonged to the age group of 26 to 30 years (31.4%). Maximum of them were from nuclear family (71.7%). 320 lactating mother (91.4%) of study participants had information about EBF. Conclusion: The majority of mothers knew about EBF and had a positive attitude towards EBF but did not know the recommended duration or that EBF is sufficient for six months. Breastfeeding counselling and health education on nutrition to the mother by health workers should be promoted.
{"title":"Knowledge, Attitude and Practice Towards Exclusive Breastfeeding Among Lactating Mothers: Descriptive Cross Sectional Study","authors":"Jatinder Singh, Vaneeta Bhardwar, Anchal Kumra","doi":"10.18311/IJMDS/2018/18906","DOIUrl":"https://doi.org/10.18311/IJMDS/2018/18906","url":null,"abstract":"Background: Exclusive breastfeeding (EBF) is the best nutrition for children during the first six months of life. However EBF remains a challenge. Objective: The aim of the study was to assess Knowledge, Attitude and Practice towards EBF among lactating mothers. Methods: A community based cross-sectional study was conducted among 350 mothers using a structured interviewer-administered questionnaire using 'recall since birth' method. Systematic random sampling was used to select the study participants and descriptive statistics were conducted. Results: Out of 350 lactating women, maximum women belonged to the age group of 26 to 30 years (31.4%). Maximum of them were from nuclear family (71.7%). 320 lactating mother (91.4%) of study participants had information about EBF. Conclusion: The majority of mothers knew about EBF and had a positive attitude towards EBF but did not know the recommended duration or that EBF is sufficient for six months. Breastfeeding counselling and health education on nutrition to the mother by health workers should be promoted.","PeriodicalId":14010,"journal":{"name":"International Journal of Medical and Dental Sciences","volume":"23 1","pages":"1586-1593"},"PeriodicalIF":0.0,"publicationDate":"2018-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74711218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-09DOI: 10.18311/ijmds/2018/18903
Vijay A G Kumar, Supratik Das
{"title":"Need of Beta 3 Agonist in Today's World as Oral Hypoglycaemic and Antiobesity","authors":"Vijay A G Kumar, Supratik Das","doi":"10.18311/ijmds/2018/18903","DOIUrl":"https://doi.org/10.18311/ijmds/2018/18903","url":null,"abstract":"","PeriodicalId":14010,"journal":{"name":"International Journal of Medical and Dental Sciences","volume":"52 1","pages":"1574-1575"},"PeriodicalIF":0.0,"publicationDate":"2018-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80349364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-09DOI: 10.18311/IJMDS/2018/18912
Baljit Jassal, Rakesh Kumar, J. K. Bajaj
Background: Premenstrual syndrome is a multifactorial psychoneurendocrine disorder. Etiology of PMS is still not demarcated & research continues in this area. Role of corelates age, parity, marital, educational & occupational status of PMS is being explored in various regions. Objective: To study sociodemographic correlates of psychological symptoms of premenstrual syndrome in woman of reproductive age group. Material and Methods: Prospective observational study was carried on 247 females in the reproductive age group. The participants were given the list of 18 preliminary symptoms and asked to encircle the symptoms they suffer during later part of the menstrual cycle in any of the last 3 cycles. In participants reporting ≥3 symptoms, the psychological symptoms were analysed and their association was observed with various sociodemographic parameters (age, location- rural/urban, marital status, parity, education, occupation). Results: 155(62.57%) reported 3 or more symptoms during later part of the menstrual cycle in the last 3 cycles. 149(96.1%) females reported at least one psychological symptom. These women showed following demographic correlates. 74.5% of females belonged to 18-26 years age group. 75.8% were unmarried. 81% had no child. 87.2% were from urban area. 71.1% were senior secondary. 96% females had mental work occupation. Conclusion: On retrospective screening there was 62.57% prevalence but on prospective follow up with PMTS & daily diary prevalence was found to be only 4.05%. Most common psychological symptom reported was irritability & there was significant association of irritability with educational status, type of work & parity. Mood swings were significantly more in females doing mental work.
{"title":"Sociodemographic Correlates of Psychological Symptoms of Premenstrual Syndrome","authors":"Baljit Jassal, Rakesh Kumar, J. K. Bajaj","doi":"10.18311/IJMDS/2018/18912","DOIUrl":"https://doi.org/10.18311/IJMDS/2018/18912","url":null,"abstract":"Background: Premenstrual syndrome is a multifactorial psychoneurendocrine disorder. Etiology of PMS is still not demarcated & research continues in this area. Role of corelates age, parity, marital, educational & occupational status of PMS is being explored in various regions. Objective: To study sociodemographic correlates of psychological symptoms of premenstrual syndrome in woman of reproductive age group. Material and Methods: Prospective observational study was carried on 247 females in the reproductive age group. The participants were given the list of 18 preliminary symptoms and asked to encircle the symptoms they suffer during later part of the menstrual cycle in any of the last 3 cycles. In participants reporting ≥3 symptoms, the psychological symptoms were analysed and their association was observed with various sociodemographic parameters (age, location- rural/urban, marital status, parity, education, occupation). Results: 155(62.57%) reported 3 or more symptoms during later part of the menstrual cycle in the last 3 cycles. 149(96.1%) females reported at least one psychological symptom. These women showed following demographic correlates. 74.5% of females belonged to 18-26 years age group. 75.8% were unmarried. 81% had no child. 87.2% were from urban area. 71.1% were senior secondary. 96% females had mental work occupation. Conclusion: On retrospective screening there was 62.57% prevalence but on prospective follow up with PMTS & daily diary prevalence was found to be only 4.05%. Most common psychological symptom reported was irritability & there was significant association of irritability with educational status, type of work & parity. Mood swings were significantly more in females doing mental work.","PeriodicalId":14010,"journal":{"name":"International Journal of Medical and Dental Sciences","volume":"16 1","pages":"1621-1627"},"PeriodicalIF":0.0,"publicationDate":"2018-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82882660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-01DOI: 10.19056/IJMDSJSSMES/2017/V6I2/149921
Mridusmita Mukherjee, K. Shekhawat
Root perforations are one of the many consequences of compromised endodontic procedure. It not only poses a significant problem in treatment outcome but also greatly affects the prognosis if not repaired in time. If it occurs, it allows microbial invasion and inflammation in the non-invated area of operation. So, choice of restorative material should be such that it closes the pathway of communication between the root canal system and its associated tissues. It should possess all the good qualities of an ideal orthograde or retrograde filling material. The following note describes a case report of a young boy with failed root canal treatment performed earlier with its steps of management.
{"title":"Perforation Repair Using Biodentine:A Nobel Approach","authors":"Mridusmita Mukherjee, K. Shekhawat","doi":"10.19056/IJMDSJSSMES/2017/V6I2/149921","DOIUrl":"https://doi.org/10.19056/IJMDSJSSMES/2017/V6I2/149921","url":null,"abstract":"Root perforations are one of the many consequences of compromised endodontic procedure. It not only poses a significant problem in treatment outcome but also greatly affects the prognosis if not repaired in time. If it occurs, it allows microbial invasion and inflammation in the non-invated area of operation. So, choice of restorative material should be such that it closes the pathway of communication between the root canal system and its associated tissues. It should possess all the good qualities of an ideal orthograde or retrograde filling material. The following note describes a case report of a young boy with failed root canal treatment performed earlier with its steps of management.","PeriodicalId":14010,"journal":{"name":"International Journal of Medical and Dental Sciences","volume":"17 1","pages":"1558-1560"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79107802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-01DOI: 10.19056/IJMDSJSSMES/2017/V6I2/149900
M. Rapotra, Anshu Sharma, M. Sharma
Background: Superficial palmar arch (SPA) is an important arterial anastomotic arcade which is the dominant vascular supply to the majority of the palmar muscles. Objectives: Keeping the importance of these variations in mind this study was designed to find out the pattern of superficial palmar arterial arches. Materials and Methods: A total of 40 adults upper limbs of unknown sex were observed for the variations in the pattern of superficial palmar arches on right and left side and were compared with the previous data. Results: A complete superficial palmar arch was encountered in 72.5% (n=29/40) of specimens and an incomplete SPA was observed in 27.5% (n=11/40) of specimens. Conclusion: Knowledge of the variations in the arterial supply of hand is essential in advent of microvascular surgery for revascularisation, replantation and composite tissue transfers.
{"title":"Pattern of Variations in Superficial Palmar Arch and its Clinical Importance","authors":"M. Rapotra, Anshu Sharma, M. Sharma","doi":"10.19056/IJMDSJSSMES/2017/V6I2/149900","DOIUrl":"https://doi.org/10.19056/IJMDSJSSMES/2017/V6I2/149900","url":null,"abstract":"Background: Superficial palmar arch (SPA) is an important arterial anastomotic arcade which is the dominant vascular supply to the majority of the palmar muscles. Objectives: Keeping the importance of these variations in mind this study was designed to find out the pattern of superficial palmar arterial arches. Materials and Methods: A total of 40 adults upper limbs of unknown sex were observed for the variations in the pattern of superficial palmar arches on right and left side and were compared with the previous data. Results: A complete superficial palmar arch was encountered in 72.5% (n=29/40) of specimens and an incomplete SPA was observed in 27.5% (n=11/40) of specimens. Conclusion: Knowledge of the variations in the arterial supply of hand is essential in advent of microvascular surgery for revascularisation, replantation and composite tissue transfers.","PeriodicalId":14010,"journal":{"name":"International Journal of Medical and Dental Sciences","volume":"7 1","pages":"1483-1487"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90475954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-01DOI: 10.19056/IJMDSJSSMES/2017/V6I2/149919
Nabil Khzam, R. Mansouri, A. Poli, Mahmoud M. Bakr
Fibrous epulis or peripheral ossifying fibroma is a reactive non-neoplastic condition that affects the gingiva as a result of chronic irritation. A case of a 44 year old female is presented in this study with a gingival swelling related to the maxillary central incisors. The Patient reported a history of trauma ten years ago and a recent root canal treatment of tooth 21, followed by referral to a specialist with a misdiagnosis for a combined periodontic-endodontic lesion affecting the maxillary central incisors. Excisional biopsy of the lesion revealed a diagnosis of ulcerated fibrous epulis with osseous metaplasia also known as peripheral ossifying fibroma. Periodontal debridement was performed to eliminate supra and subgingival plaque and calculus as well as gingival inflammation that could have been the source of irritation. The clinical and histopathological pictures and the surgical procedures associated with management of the periodontal disease are described. The etiological factor behind the development of the gingival reactive lesion remains unknown and could be the history of trauma, the chronic irritation induced by the plaque and calculus associated with the periodontal disease or a combination of both. We endeavour to follow up the case in order to report any recurrence.
{"title":"Fibrous Epulis Misdiagnosed for Combined Periodontic-Endodontic Lesion","authors":"Nabil Khzam, R. Mansouri, A. Poli, Mahmoud M. Bakr","doi":"10.19056/IJMDSJSSMES/2017/V6I2/149919","DOIUrl":"https://doi.org/10.19056/IJMDSJSSMES/2017/V6I2/149919","url":null,"abstract":"Fibrous epulis or peripheral ossifying fibroma is a reactive non-neoplastic condition that affects the gingiva as a result of chronic irritation. A case of a 44 year old female is presented in this study with a gingival swelling related to the maxillary central incisors. The Patient reported a history of trauma ten years ago and a recent root canal treatment of tooth 21, followed by referral to a specialist with a misdiagnosis for a combined periodontic-endodontic lesion affecting the maxillary central incisors. Excisional biopsy of the lesion revealed a diagnosis of ulcerated fibrous epulis with osseous metaplasia also known as peripheral ossifying fibroma. Periodontal debridement was performed to eliminate supra and subgingival plaque and calculus as well as gingival inflammation that could have been the source of irritation. The clinical and histopathological pictures and the surgical procedures associated with management of the periodontal disease are described. The etiological factor behind the development of the gingival reactive lesion remains unknown and could be the history of trauma, the chronic irritation induced by the plaque and calculus associated with the periodontal disease or a combination of both. We endeavour to follow up the case in order to report any recurrence.","PeriodicalId":14010,"journal":{"name":"International Journal of Medical and Dental Sciences","volume":"96 1","pages":"1546-1552"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73933337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-01DOI: 10.19056/IJMDSJSSMES/2017/V6I2/149912
Dakshata Dinesh Sankhe
Background: Root canal preparations done using many rotary endodontic instruments results in formation of root dentin defects because of the stress induced by the instruments within the root canal during cleaning and shaping, thereby worsening the long term prognosis of the root canal treated teeth. Many rotary instruments are been globally studied for the purpose of generating a correct instrument for root canal preparation. Objective: This study was done to evaluate the effect of HyFlex EDM, which is a new rotary system on root dentin during root canal preparation. Materials and methods: Fourteen single rooted premolars were selected and divided into two groups, Group 1-Protaper Universal and Group 2-HyFlex EDM. All the specimens were decoronated. Roots of each specimen were sectioned at 3mm, 6mm and 9mm and were then viewed under stereomicroscope for dentinal defects. t-test was done for the statistical analysis and level of significance was set at p=0.05. Results: Protaper Universal showed highest percentage of defect than HyFlex EDM. Conclusion: HyFlex EDM showed lowest percentage of defects in root dentin. Thus, HyFlex EDM is more efficient in root canal preparation than that of Protaper Universal thereby preventing dentinal defects or microcracks leading to root fractures.
{"title":"Evaluation of Effect of Hyflex EDM on Root Dentin during Root Canal Preparation-A Stereomicroscopic Study","authors":"Dakshata Dinesh Sankhe","doi":"10.19056/IJMDSJSSMES/2017/V6I2/149912","DOIUrl":"https://doi.org/10.19056/IJMDSJSSMES/2017/V6I2/149912","url":null,"abstract":"Background: Root canal preparations done using many rotary endodontic instruments results in formation of root dentin defects because of the stress induced by the instruments within the root canal during cleaning and shaping, thereby worsening the long term prognosis of the root canal treated teeth. Many rotary instruments are been globally studied for the purpose of generating a correct instrument for root canal preparation. Objective: This study was done to evaluate the effect of HyFlex EDM, which is a new rotary system on root dentin during root canal preparation. Materials and methods: Fourteen single rooted premolars were selected and divided into two groups, Group 1-Protaper Universal and Group 2-HyFlex EDM. All the specimens were decoronated. Roots of each specimen were sectioned at 3mm, 6mm and 9mm and were then viewed under stereomicroscope for dentinal defects. t-test was done for the statistical analysis and level of significance was set at p=0.05. Results: Protaper Universal showed highest percentage of defect than HyFlex EDM. Conclusion: HyFlex EDM showed lowest percentage of defects in root dentin. Thus, HyFlex EDM is more efficient in root canal preparation than that of Protaper Universal thereby preventing dentinal defects or microcracks leading to root fractures.","PeriodicalId":14010,"journal":{"name":"International Journal of Medical and Dental Sciences","volume":"24 1","pages":"1525-1528"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79261105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-01DOI: 10.19056/IJMDSJSSMES/2017/V6I2/149897
M. Priyadharshini, R. Narmadha, S. Dhanalakshmi, R. Natarajan, S. Subitha, C. Suganthi, Padmavathy
Background: Gastric carcinomas have various pathological features. Based on patterns of growth and invasiveness, however, they fall into two types: diffuse type and intestinal type. These two types of carcinoma appear to be different in their histogenetic origins. Objectives: To analyse various types of gastric cancer reported in last five years. To compare the features of intestinal and diffuse type gastric carcinoma including gross appearance, staging, grading of tumor. Materials and Methods: This was a retrospective study of 324 gastric cancer which were surgically resected and received over 5 years. The tumors were divided into groups according to their gross and microscopic patterns. Gross appearance was classified based on Borrmann classification. Microscopic features evaluated include tumor cell type, extent of invasion, degree of maturation, formation of glandular structures, nodal metastasis. Results: Totally 320 cases of gastric cancer were received of which 218(68%) were male, 102(32%) were female. Gastric cancers are rare below the age of 30 years. Comparing the type of gastric cancer intestinal type were 269(84%), diffuse type were 24(7.5%) and other type of gastric cancer including GIST, lymphoma, mucinous adenocarcinoma were 27(8.5%). Younger patients have higher stage of lymph node metastasis in diffuse type, but not for the intestinal type. Conclusion: Gastric cancer more common in male (M:F= 2:1) and most frequently seen in 5th decade. Intestinal type constitutes the most common type of gastric tumor. Gross appearance of diffuse type was predominantly infiltrative (79%).
{"title":"Pathobiological Characteristics of Intestinal and Diffuse-Type of Gastric Carcinoma-Retrospective Study of Gastric Cancers","authors":"M. Priyadharshini, R. Narmadha, S. Dhanalakshmi, R. Natarajan, S. Subitha, C. Suganthi, Padmavathy","doi":"10.19056/IJMDSJSSMES/2017/V6I2/149897","DOIUrl":"https://doi.org/10.19056/IJMDSJSSMES/2017/V6I2/149897","url":null,"abstract":"Background: Gastric carcinomas have various pathological features. Based on patterns of growth and invasiveness, however, they fall into two types: diffuse type and intestinal type. These two types of carcinoma appear to be different in their histogenetic origins. Objectives: To analyse various types of gastric cancer reported in last five years. To compare the features of intestinal and diffuse type gastric carcinoma including gross appearance, staging, grading of tumor. Materials and Methods: This was a retrospective study of 324 gastric cancer which were surgically resected and received over 5 years. The tumors were divided into groups according to their gross and microscopic patterns. Gross appearance was classified based on Borrmann classification. Microscopic features evaluated include tumor cell type, extent of invasion, degree of maturation, formation of glandular structures, nodal metastasis. Results: Totally 320 cases of gastric cancer were received of which 218(68%) were male, 102(32%) were female. Gastric cancers are rare below the age of 30 years. Comparing the type of gastric cancer intestinal type were 269(84%), diffuse type were 24(7.5%) and other type of gastric cancer including GIST, lymphoma, mucinous adenocarcinoma were 27(8.5%). Younger patients have higher stage of lymph node metastasis in diffuse type, but not for the intestinal type. Conclusion: Gastric cancer more common in male (M:F= 2:1) and most frequently seen in 5th decade. Intestinal type constitutes the most common type of gastric tumor. Gross appearance of diffuse type was predominantly infiltrative (79%).","PeriodicalId":14010,"journal":{"name":"International Journal of Medical and Dental Sciences","volume":"49 1","pages":"1462-1467"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89788704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-01DOI: 10.19056/IJMDSJSSMES/2017/V6I2/149923
Rakesh Kumar, Baljit Jassal, A. Sehgal
Rheumatoid arthritis is a debilitating disease that has significant impact on quality of life. Biological and non biological DMARDs improved the outcome in RA patients. New agents are still required in inadequate responders or intolerant patients. FDA has recently approved a new drug Sarilumab, a monoclonal antibody for the treatment of moderate to severe form of RA which acts by binding to Interleukin receptor 6 and interrupts the resultant cytokine-mediated inflammatory signaling.
{"title":"Sarilumab:A New Arsenal for Rheumatoid Arthritis","authors":"Rakesh Kumar, Baljit Jassal, A. Sehgal","doi":"10.19056/IJMDSJSSMES/2017/V6I2/149923","DOIUrl":"https://doi.org/10.19056/IJMDSJSSMES/2017/V6I2/149923","url":null,"abstract":"Rheumatoid arthritis is a debilitating disease that has significant impact on quality of life. Biological and non biological DMARDs improved the outcome in RA patients. New agents are still required in inadequate responders or intolerant patients. FDA has recently approved a new drug Sarilumab, a monoclonal antibody for the treatment of moderate to severe form of RA which acts by binding to Interleukin receptor 6 and interrupts the resultant cytokine-mediated inflammatory signaling.","PeriodicalId":14010,"journal":{"name":"International Journal of Medical and Dental Sciences","volume":"15 1","pages":"1571-1573"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73598661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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