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Dry eye disease - are we underselling it? An epidemic in the offing and future management trends 干眼症——我们是否在低价出售?即将发生的流行病和未来的管理趋势
Pub Date : 2021-01-01 DOI: 10.33545/26638266.2021.v3.i1a.60
Sinchana Adyanthaya, B. Abhilash
Dry eye definition and management has seen a complete overhaul over the past two decades. With increasing life style changes the incidence of DED has exponentially increased and it’s not relevant only to the developed world anymore. The earlier thought demography of patients susceptible for dry eye has also changed considerably. In India the prevalence of dry eye ranges from 18.4% to 40.8%. This increasing incidence of DED has provided a sling shot for many pharmaceutical industry leaders to come up with novel innovative treatment methodologies for holistic management of dry eye disease. In our brief communication we look at the history of dry eye diagnosis and management and future treatment options available for treating clinicians to tackle the epidemic of DED.
在过去的二十年里,干眼的定义和管理经历了彻底的改革。随着生活方式的改变,DED的发病率呈指数增长,它不再仅仅与发达国家有关。以前认为易患干眼症的患者的人口统计学也发生了很大的变化。在印度,干眼症的患病率从18.4%到40.8%不等。干眼症的发病率不断上升,这为许多制药行业的领导者提供了一个新的创新治疗方法,以全面管理干眼症。在我们的简短交流中,我们看看干眼诊断和管理的历史,以及治疗临床医生应对DED流行的未来治疗方案。
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引用次数: 1
Evaluation of change in intraocular pressure and macular thickness after Nd: YAG laser posterior capsulotomy Nd: YAG激光后囊切开术后眼压及黄斑厚度变化的评价
Pub Date : 2021-01-01 DOI: 10.33545/26638266.2021.V3.I1B.76
Munavvar Ansari, Farhat Abrar
Purpose: To evaluate the changes in intraocular pressure and macular thickness after Nd: Yag laser posterior capsulotomy. Methodology: This prospective study included 91 eyes of 78 patients who were diagnosed as posterior capsule opacification (PCO), following uncomplicated cataract surgery. All the patients were examined preoperatively and 1 hour post-procedure, 1 week and 4 weeks after Nd: YAG capsulotomy. IOP and macular thickness of all the patients was measured by Goldmann applanation tonometry and optical coherence tomography (OCT), respectively before performing the procedure and at subsequent visits. Patients were divided into two groups based on energy used (Group I ≤50 mJ, Group II >50 mJ). None of the patients received prophylactic antiglaucoma medications either before or after the procedure. Results: There were 42 males and 36 female patients included in the study. Mean age of the patients was 53.87 ± 10.24 years (45-80 years). Mean total energy levels were 38.64±13.92 mJ in Group I and 85.76±22.10 mJ in Group II. In Group I, IOP did not increase at 1 hour postoperatively (P=0.063) and was within normal limits at 1 week and 4 weeks. In Group II, IOP increased at 1 hour postoperatively (P
目的:评价Nd: Yag激光后囊膜切开术后眼压和黄斑厚度的变化。方法:本前瞻性研究包括78例诊断为后囊膜混浊(PCO)的患者,共91眼,均行无并发症白内障手术。所有患者术前、术后1小时、Nd: YAG囊切除术后1周和4周进行检查。所有患者术前及随访时分别采用Goldmann眼压测量仪和光学相干断层扫描(OCT)测量眼压和黄斑厚度。根据能量消耗情况将患者分为两组(I组≤50 mJ, II组>50 mJ)。所有患者在手术前后均未接受预防性抗青光眼药物治疗。结果:男性42例,女性36例。患者平均年龄为53.87±10.24岁(45 ~ 80岁)。组平均总能量水平为38.64±13.92 mJ,组平均总能量水平为85.76±22.10 mJ。I组术后1小时IOP未升高(P=0.063),术后1周和4周IOP均在正常范围内。II组术后1小时IOP升高(P
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引用次数: 0
Study of knowledge, practice about eye donation among medical and paramedical students in eye OPD 眼科专业医、准医学生眼部捐赠知识与实践的研究
Pub Date : 2021-01-01 DOI: 10.33545/26638266.2021.v3.i2b.151
Dr. Kedar Nemivant, Dr. Shaikh Najamoddin
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引用次数: 0
Radiation retinopathy masquerading diabetic retinopathy 放射性视网膜病变伪装成糖尿病视网膜病变
Pub Date : 2021-01-01 DOI: 10.33545/26638266.2021.v3.i1b.68
J. ShahVinit, Y. C. V. G. Reddy, S. Ka, S. Adeel, Nair Shobita
Background: Radiation retinopathy (RR) can occur years after irradiation as a chronic and progressive retinal micro-angiopathy. The presentations of RR are similar to other retinal vaso-occlusive disorders like diabetic retinopathy, hypertensive retinopathy. The patient was referred to us as a case of diabetic retinopathy who had received intravitreal injections for macular edema without any improvement. A thorough evaluation revealed it to be a case of Radiation retinopathy. RR treatment includes laser photocoagulation, intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections, intravitreal steroid injections, and surgery. Case presentation: We report a case of a 47-year-old diabetic male patient in whom RR developed following 30Gy of radiation therapy for Ethmoidal sinus carcinoma masquerading as Diabetic retinopathy. FFA was showing extensive ischemia of the retina, and OCT showing Macular edema. He received Pan retinal photocoagulation in both eyes followed by multiple intravitreal Anti-VEGF injections on a PRN basis and underwent Pars plana vitrectomy in the right eye for non-resolving vitreous hemorrhage. Conclusion: The patient's vision improved only after treating the retinal ischemia with photocoagulation and later treating the macular edema. This report emphasizes the importance of differentiating this disease entity from other vaso-occlusive retinopathy by eliciting a detailed patient history and planning further management accordingly.
背景:放射性视网膜病变(RR)可在照射后数年发生,是一种慢性进行性视网膜微血管病变。RR的表现与其他视网膜血管闭塞性疾病如糖尿病视网膜病变、高血压视网膜病变相似。该患者作为糖尿病视网膜病变的病例被提交给我们,他接受了黄斑水肿的玻璃体内注射,没有任何改善。经全面检查,诊断为放射性视网膜病变。RR治疗包括激光光凝、玻璃体内抗血管内皮生长因子(anti-VEGF)注射、玻璃体内类固醇注射和手术。病例介绍:我们报告一例47岁的男性糖尿病患者,在接受30Gy的筛窦癌放疗后出现RR,并伪装成糖尿病视网膜病变。FFA显示视网膜大面积缺血,OCT显示黄斑水肿。双眼接受视网膜光凝治疗,并在PRN基础上进行多次玻璃体内抗vegf注射,右眼因玻璃体出血不溶解行玻璃体切除。结论:光凝治疗视网膜缺血后再治疗黄斑水肿,患者视力才有改善。本报告强调通过详细的患者病史和相应的进一步治疗计划来区分这种疾病与其他血管闭塞性视网膜病变的重要性。
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引用次数: 0
Serum cortisol and serum testosterone levels in idiopathic central serous chorioretinopathy 特发性中枢性浆液性脉络膜视网膜病变的血清皮质醇和血清睾酮水平
Pub Date : 2021-01-01 DOI: 10.33545/26638266.2021.v3.i1b.82
Arman Dawar, Farhat Abrar, C. Jain
Aim: To analyse the serum cortisol and serum testosterone levels in idiopathic central serous chorioretinopathy. Material and methods: The prospective interventional study was conducted in the central laboratory associated with the Department of Ophthalmology, Subharti Medical College, Meerut. A study was conducted in 30 cases of CSR. The patients were divided into two groups i.e. Group A (15 patients with unilateral sudden painless loss of vision of less than one month of duration serving as cases and Group B (15 patients with no signs and symptoms serving as control). Evaluation of Macular thickness was done using OPTOVUE RTvue 100 OCT procedure. After pupil dilation, the patient is seated at the machine, asked to fixate at the internal fixation point and scan is obtained. The macular thickness map was taken to measure the thickness of macula. Fundus Fluorescein Angiography (FFA) was done, if required. Patients of both the groups underwent investigations such as dilated fundus examination, serum cortisol and serum testosterone levels. Results: Mean serum cortisol (μg/dL) among the case group was higher as compared to the control group with statistically significant difference as p
目的:分析特发性中枢性浆液性脉络膜视网膜病变患者血清皮质醇和睾酮水平。材料和方法:前瞻性介入研究在密鲁特Subharti医学院眼科中心实验室进行。对30例CSR进行了研究。将患者分为两组,A组(15例单侧突发性无痛性视力丧失患者,持续时间小于1个月)为病例,B组(15例无症状体征患者为对照组)。使用OPTOVUE RTvue 100 OCT程序评估黄斑厚度。瞳孔扩张后,患者坐在机器前,被要求固定在内固定点上并扫描。采用黄斑厚度图测量黄斑厚度。如有需要,行眼底荧光素血管造影(FFA)。两组患者均接受了眼底扩张检查、血清皮质醇和血清睾酮水平等调查。结果:病例组平均血清皮质醇(μg/dL)高于对照组,差异有统计学意义(p
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引用次数: 0
A case control study of estimation of vitamin D3 levels in patients with lenticular opacity aged between 18-50 years in a tertiary institute in India 在印度一所高等教育机构对18-50岁透镜状混浊患者的维生素D3水平进行了病例对照研究
Pub Date : 2021-01-01 DOI: 10.33545/26638266.2021.V3.I1B.74
Adyanthaya Sinchana, B. Abhilash
Background & Objectives: Ocular diseases like cataract, diabetic retinopathy, glaucoma and ARMD are some of the ocular associations observed in patients with deficient Vitamin D levels. Although earlier studies have addressed the issue of metabolic factors leading to cataract in infants, studies on adults is lacking. In our current study we intend to assess and analyse the serum vitamin D3 levels in patients with early cataractous changes aged
背景与目的:白内障、糖尿病视网膜病变、青光眼和ARMD等眼部疾病是维生素D缺乏患者的眼部相关疾病。虽然早期的研究已经解决了代谢因素导致婴儿白内障的问题,但缺乏对成人的研究。在我们目前的研究中,我们打算评估和分析老年早期白内障患者的血清维生素D3水平
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引用次数: 0
Assessment of clinical profile of patients with uveitis 葡萄膜炎患者的临床特征评估
Pub Date : 2020-07-01 DOI: 10.33545/26638266.2020.V2.I2B.46
R. Sood, R. Sood
Background: The present study was conducted to assess clinical profile of patients with uveitis. Materials & Methods: 62 cases of uveitis underwent Visual acuity by Snellen’s chart, refraction, intraocular pressure by applanation tonometry, slit lamp biomicroscopic examination and a detailed fundus examination. Results: Clinical types were acute in 36, chronic in 18 and recurrent in 8 cases. The difference was significant ( P< 0.05). The common etiology was lens induced in 14, herpetic infection in 24, tuberculosis in 8, blunt trauma in 10 and Behcets disease in 4 cases. The difference was significant ( P< 0.05). Conclusion: Maximum cases were observed in males and common etiology was lens induced and herpetic infection.
背景:本研究旨在评估葡萄膜炎患者的临床特征。材料与方法:对62例葡萄膜炎患者行斯伦氏视力表视力检查、屈光检查、眼压压检查、裂隙灯生物显微镜检查及眼底详细检查。结果:临床分型为急性36例,慢性18例,复发8例。差异有统计学意义(P< 0.05)。常见病因为晶状体所致14例,疱疹感染24例,结核8例,钝性创伤10例,贝塞特病4例。差异有统计学意义(P< 0.05)。结论:以男性为主,常见病因为晶状体感染和疱疹性感染。
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引用次数: 0
Study to find the indications and adverse reactions in patients receiving intravitreal injections at ophthalmology unit, RVM hospital, Telangana state, India 印度特伦甘纳邦RVM医院眼科部门玻璃体内注射患者的适应证和不良反应研究
Pub Date : 2020-07-01 DOI: 10.33545/26638266.2020.v2.i2a.38
Venkataswamy, Manoj Patruni, Chinthala Narsaiah
Introduction: Intravitreal injection of air was first used by Ohm in 1911 for repairing retinal detachments. Intravitreal pharmacotherapy is likely to increase as more and more agents are being developed and tested for a variety of retinal diseases. Methodology: A hospital based prospective randomised interventional study conducted on patients attending ophthalmology department of RVM Hospital from May 2019 to March 2020, where intravitreal injections of Triamcinolone acetonide (4mg/0.1 ml), Bevacizumab (1.25mg/0.05ml), Ranibizumab (0.5mg/0.05ml), Ganciclovir (2mg/0.1ml) were injected for various vitreoretinal diseases. Results: The common age group was 46-60 years in this study and the age group of 16-30 were limited in this study. Age-related macular degeneration (AMD) was 148, retinal vein occlusion (RVO) 169, Proliferative Diabetic Retinopathy (PDR) 114 were main indications for intravitreal injection therapy and the least being Coats disease 3, and idiopathic polypoidal choroidal vasculopathy (IPCV) 3. Bevacizumab is the drug which was used excessively in this study as intravitreal injection (57.45%) followed by Ranibizumab (19.66%) and the least being Ganciclovir (10.33%). Conclusion: Intravitreal injection is a safe and efficient technique. The risk of serious vision threatening complications is very low.
简介:1911年欧姆首次使用玻璃体内注射空气来修复视网膜脱离。随着越来越多的药物被开发和测试用于各种视网膜疾病,玻璃体内药物治疗可能会增加。方法:以2019年5月至2020年3月在RVM医院眼科就诊的患者为研究对象,采用基于医院的前瞻性随机介入研究方法,采用玻璃体腔注射曲安奈德(4mg/0.1 ml)、贝伐单抗(1.25mg/0.05ml)、雷尼单抗(0.5mg/0.05ml)、更昔洛韦(2mg/0.1ml)治疗各种玻璃体视网膜疾病。结果:本研究以46 ~ 60岁为常见年龄组,16 ~ 30岁为有限年龄组。年龄相关性黄斑变性(AMD) 148例,视网膜静脉阻塞(RVO) 169例,增殖性糖尿病视网膜病变(PDR) 114例是玻璃体内注射治疗的主要适应症,最少的是Coats病3例,特发性息肉样脉络膜血管病变(IPCV) 3例。贝伐单抗是本研究中玻璃体内注射使用最多的药物(57.45%),其次是雷尼单抗(19.66%),更昔洛韦最少(10.33%)。结论:玻璃体内注射是一种安全、有效的方法。严重视力威胁并发症的风险非常低。
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引用次数: 0
Observational study on ocular manifestations in type 2 diabetes patients attending the ophthalmology department, at RVM hospital, South India 印度南部RVM医院眼科2型糖尿病患者眼部表现的观察性研究
Pub Date : 2020-07-01 DOI: 10.33545/26638266.2020.v2.i2a.37
Venkataswamy, Manoj Patruni, Chinthala Narsaiah
Introduction: India is infamously known as the Diabetes capital of the world. The national wide prevalence of diabetes in India now is 9%. By 2030, India will have 100 million people with type 2 Diabetes. Methodology: Cross sectional observational study, Study was conducted in ophthalmology department at RVM Hospital, Siddipet District, and Telangana State. The study was conducted in April 2018 to December 2019.The Sample Size is 300. Results: 188(63%) were males and 112(37%) are females. Among both sexes, age groups between 51 to 60 years had maximum number of patients (34%).33 patients had some lid lesions, out of which 12 had stye followed by 10 had Xanthelasma Conjunctival lesions found were pterygium 13(4.33%) and conjunctivitis 6(2%).6 patients had corneal ulceration (2%), 3 had reduced corneal sensation (1.0%) while 1 patient had perforation (0.33%). 11.5% people are affected by mild NPDR within 5 years, which increases significantly to 26.6% in 10 years. Conclusion: Thus both prevalence and severity of retinopathy correlates with HbA1C levels in this study group. The most common type of cataract found was cortical type (39.13%) followed by senile posterior cortical cataract (32.60%). In general, the visual prognosis following cataract surgery in diabetic patients is favourable. The prevalence of Primary open angle glaucoma was 2.33% and 2.0% had neo-vascular glaucoma. Diabetes predisposes to infection in different body parts, and ocular structures are not an exception.
导读:印度是臭名昭著的世界糖尿病之都。目前印度全国糖尿病患病率为9%。到2030年,印度将有1亿人患有2型糖尿病。方法:横断面观察研究,研究在泰伦加纳邦Siddipet区RVM医院眼科进行。该研究于2018年4月至2019年12月进行。样本量是300。结果:男性188例(63%),女性112例(37%)。在两性中,51至60岁年龄组的患者人数最多(34%)。结膜病变中,翼状胬肉13例(4.33%),结膜炎6例(2%)。角膜溃疡6例(2%),角膜感觉减退3例(1.0%),穿孔1例(0.33%)。11.5%的人在5年内受到轻度NPDR的影响,10年内显着增加到26.6%。结论:在本研究组中,视网膜病变的患病率和严重程度与HbA1C水平相关。最常见的白内障类型为皮质型(39.13%),其次为老年性后皮质型(32.60%)。一般来说,糖尿病患者白内障手术后视力预后良好。原发性开角型青光眼患病率为2.33%,新血管性青光眼患病率为2.0%。糖尿病容易在身体的不同部位感染,眼部结构也不例外。
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引用次数: 0
Variation in central corneal thickness in diabetes: A comparative prospective study at a tertiary care hospital 糖尿病患者角膜中央厚度的变化:一家三级医院的比较前瞻性研究
Pub Date : 2020-07-01 DOI: 10.33545/26638266.2020.V2.I2B.50
J. Jacob, I. Isaac, Janie Salor, N. Rajendran
Diabetes being the greatest challenge of the century and the fact that it affects almost all of the tissues and organs in the body warrants research into the effects of diabetes on every structure. This study was designed with the aim of finding out any association between diabetes and central corneal thickness and to evaluate the effect of diabetes treatment on central corneal thickness. and non-diabetic A comparative prospective study was conducted to evaluate the effect of on CCT. A total of 84 subjects were studied which included 42 diabetics. After thorough systemic and ocular CCT was measured using ultrasound pachymeter. The study was initiated after obtaining ethical clearance from the ethical clearance committee. The collected data was analysed using SPSS software version 20.0. to bring to light the effects of diabetes on corneal thickness, which in turn might affect even the management of glaucoma. We evaluated a group of diabetics and compared them with matched controls. After conducting this study we arrived at a conclusion that central corneal thickness is increased in diabetics and that control of diabetes doesn’t have a significant effect on central corneal thickness.
糖尿病是本世纪最大的挑战,它影响人体几乎所有的组织和器官,这一事实值得研究糖尿病对每个结构的影响。本研究旨在探讨糖尿病与角膜中央厚度之间的关系,并评价糖尿病治疗对角膜中央厚度的影响。进行了一项比较前瞻性研究,以评估对CCT的影响。共有84名受试者被研究,其中包括42名糖尿病患者。超声测厚仪测量全身及眼部CCT。该研究是在获得伦理审查委员会的伦理许可后开始的。采用SPSS 20.0软件对收集的数据进行分析。揭示糖尿病对角膜厚度的影响,进而影响青光眼的治疗。我们对一组糖尿病患者进行了评估,并与对照组进行了比较。在进行这项研究后,我们得出结论,糖尿病患者角膜中央厚度增加,糖尿病的控制对角膜中央厚度没有显著影响。
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引用次数: 0
期刊
International Journal of Medical Ophthalmology
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