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A study of retinal changes in diabetes mellitus in association with glycosylated haemoglobin, haemoglobin and duration of diabetes mellitus in tertiary care teaching hospital 三级教学医院糖尿病视网膜病变与糖化血红蛋白、血红蛋白及糖尿病病程的关系
Pub Date : 2021-01-01 DOI: 10.33545/26638266.2021.V3.I1B.88
Anusha N Sangapur, Ravi N Sangapur, Varsha Huralikoppi
Introduction: Prevalence of diabetic retinopathy in India is 21.27%. Diabetic retinopathy was detected in 1.78% of the diabetic patients screened. Diabetic retinopathy is a major, potentially preventable, long term, microvascular complication of diabetes mellitus and a leading cause of visual disability and blindness in working-age population, which is the hallmark of generalized microangiopathy.Materials and Methods: This is Cross Sectional Study Conducted Among Out Patients attending Ophthalmology OPD and Inpatients of tertiary care teaching hospital. Patients were enrolled for the study after obtaining written informed consent. Total 214 patients were screened in this study. Staging of Diabetic Retinopathy was done using Modified Arlie House classification. Result: Amongst the total number of diabetic retinopathy patients, 138 (64.5%) patients were males and 76 (35.5%) patients were females. Out of the total number of females in the study 77.6% had diabetic retinopathy and amongst males 73.1% had diabetic retinopathy and severity of DR is more in males (10.9% versus 7.9%). There was no statistical significance seen with gender and diabetic retinopathy (chi square x2 =1.819, p=0.611). Retinopathy was seen in 74.8% of the subjects in study. Among them 37.9% were shown mild changes of DR and whereas 9.8% were having severe or very severe retinopathy. Median duration of diabetes is 2 years. Among them 15.9% were having diabetes for more than 10 years and 11.7% had from less than 1 year duration. Maximum number of people (35.5%) were having the duration of 1 - 5year.A positive co-orelation was observed between glycosylated haemoglobin and haemoglobin with severity of diabetic retinopathy. Conclusion: Glycosylated Hemoglobin levels was significantly correlated to severity of diabetic retinopathy. Haemoglobin level have been significantly correlated to severity of diabetic retinopathy. Glucose control and anemia are identified to be important modifiable risk factors in diabetes mellitus patients. The presence of these risk factors should warn the ophthalmologists about the need to monitor the retina. Low haemoglobin level, which is common in patients from developing countries like India, needs to be detected and treated, thereby reducing the risk for developing DR.
印度糖尿病视网膜病变的患病率为21.27%。筛查的糖尿病患者中有1.78%检出糖尿病视网膜病变。糖尿病视网膜病变是糖尿病的主要、可预防的长期微血管并发症,也是导致工作年龄人群视力残疾和失明的主要原因,是全身性微血管病变的标志。材料与方法:本研究为横断面研究,对象为眼科门诊患者与三级教学医院住院患者。患者在获得书面知情同意后被纳入研究。本研究共筛选了214例患者。采用改良Arlie House分类法对糖尿病视网膜病变进行分期。结果:糖尿病视网膜病变患者中,男性138例(64.5%),女性76例(35.5%)。在研究的女性中77.6%患有糖尿病视网膜病变,男性中73.1%患有糖尿病视网膜病变,男性DR的严重程度更高(10.9%对7.9%)。性别与糖尿病视网膜病变差异无统计学意义(χ 2 =1.819, p=0.611)。74.8%的受试者出现视网膜病变。37.9%的患者表现为轻度病变,9.8%的患者表现为重度或极重度视网膜病变。糖尿病的中位病程为2年。其中15.9%的患者糖尿病病程在10年以上,11.7%的患者糖尿病病程在1年以下。最多的人(35.5%)的期限为1 - 5年。糖化血红蛋白和血红蛋白与糖尿病视网膜病变的严重程度呈正相关。结论:糖化血红蛋白水平与糖尿病视网膜病变严重程度显著相关。血红蛋白水平与糖尿病视网膜病变的严重程度显著相关。血糖控制和贫血是糖尿病患者重要的可改变的危险因素。这些危险因素的存在应该提醒眼科医生注意监测视网膜的必要性。血红蛋白水平低在印度等发展中国家的患者中很常见,需要进行检测和治疗,从而降低发生耐多药症的风险。
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引用次数: 0
Effect of single intravitreal triamcinolone acetonide injection on intraocular pressure and retinal nerve fibre layer thickness 单次玻璃体内注射曲安奈德对眼压及视网膜神经纤维层厚度的影响
Pub Date : 2021-01-01 DOI: 10.33545/26638266.2021.v3.i1a.80
Shazia Arrin, Simi Zaka-ur-rab
Purpose: To investigate the intraocular pressure (IOP) changes following intravitreal triamcinolone acetonide (IVTA) injection for inflammatory, proliferative and edematous diseases of posterior segment of eye. Design: Prospective longitudinal interventional study. Methods: The prospective longitudinal study included 30 with posterior uveitis (n=12), retinal vascular occlusive diseases (n=10), Eales’ disease (n=6), pseudophakic cystoid macular edema (n=1) and idiopathic cystoid macular edema (n=1). 4 mg of IVTA injection IOP increased significantly from baseline IOP of 14.27±3.53 mm Hg to mean IOP of 16.54± 4.29, 18.54± 5.50, 19.00± 5.98, 18.82± 5.00 and 22.50±0.71 mm Hg at 2, 4, 6, 8 and 12 weeks follow up respectively. In study group IOP elevation of ≥6 mm Hg from baseline was seen in 17 out of 30 eyes (64.71% males and 35.29%females). The majority of patients belonged to younger age group. An IOP elevation was seen in 58.82% and 88.24% eyes upto 4 and 6 weeks follow up respectively. In 15 out of 17 eyes, IOP was controlled with topical anti-glaucoma medications while 2 eyes required filtering glaucoma surgery. Conclusions: After 4 mg of IVTA injection 57.67% of eyes developed IOP elevation ≥6 mm Hg from baseline. In 88.24% eyes raised IOP was controlled with topical anti-glaucoma medications. There was no statistically significant change observed in retinal nerve fibre layer thickness upto 12 weeks follow up, despite elevated IOP. Besides glaucoma no other complication was observed upto 12 weeks of follow up.
目的:探讨曲安奈德(IVTA)治疗眼后段炎症性、增生性和水肿性疾病后玻璃体内注射曲安奈德后眼压(IOP)的变化。设计:前瞻性纵向介入研究。方法:前瞻性纵向研究包括30例后葡萄膜炎(n=12)、视网膜血管闭塞性疾病(n=10)、Eales病(n=6)、假性晶状体囊样黄斑水肿(n=1)和特发性囊样黄斑水肿(n=1)。在随访2、4、6、8、12周时,IVTA注射4 mg的IOP分别从基线的14.27±3.53 mm Hg升高至16.54±4.29、18.54±5.50、19.00±5.98、18.82±5.00和22.50±0.71 mm Hg。在研究组中,30只眼中有17只眼眼压比基线升高≥6 mm Hg(64.71%为男性,35.29%为女性)。患者以低龄组居多。随访4周和6周时,眼压升高分别为58.82%和88.24%。在17只眼睛中,有15只眼睛的眼压通过局部抗青光眼药物控制,而2只眼睛需要进行滤过性青光眼手术。结论:注射4 mg IVTA后,有57.67%的眼眼压较基线升高≥6 mm Hg。88.24%的眼压升高者使用局部抗青光眼药物控制眼压。尽管IOP升高,但随访12周后,视网膜神经纤维层厚度无统计学意义变化。随访12周,除青光眼外未见其他并发症。
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引用次数: 0
Pattern of uveitis: A study at regional eye hospital 地区眼科医院的葡萄膜炎类型研究
Pub Date : 2021-01-01 DOI: 10.33545/26638266.2021.v3.i1a.91
D. Archana
Aim & Objectives: To study the pattern of uveitis and common causes of uveitis in our region. Methodology: In the present study, 100 patients with uveitis, attending Regional Eye Hospital, Warangal were included. The average age of presentation these patients was around 40 years with no significant gender preponderance. All patients underwent a through systemic and ocular examination. A tailored laboratory investigation was done in each case to facilitate diagnosis. Results: Most common type of uveitis in our study was anterior uveitis which was chronic and noninfectious in nature. Diagnosis was made with respect to the type and etiology of uveitis. Etiology remained undetermined in majority of cases. Most common cause in present study was Tuberculosis and Rheumatoid arthritis. Most common complications were macular oedema and raised intraocular pressure. Majority of patients responded well to treatment. Conclusion: The most common specific etiology was tuberculosis; however most of the cases were idiopathic. There was no significant sex predisposition seen.
目的:了解本地区葡萄膜炎的发病特点及常见原因。方法:本研究纳入100例在瓦朗加尔地区眼科医院就诊的葡萄膜炎患者。这些患者的平均发病年龄在40岁左右,无明显的性别优势。所有患者均接受了全面的全身和眼部检查。为便于诊断,对每个病例进行了量身定制的实验室调查。结果:本研究中最常见的葡萄膜炎类型为前葡萄膜炎,为慢性非感染性。根据葡萄膜炎的类型和病因进行诊断。大多数病例的病因仍未确定。本研究中最常见的病因是结核和类风湿关节炎。最常见的并发症是黄斑水肿和眼压升高。大多数病人对治疗反应良好。结论:最常见的特异性病因为结核;然而大多数病例是特发性的。没有明显的性别倾向。
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引用次数: 0
Analysis of the AC/A ratio in myopia patients in relation to spectacles and soft contact lenses 近视患者配戴眼镜与软性隐形眼镜的AC/A比值分析
Pub Date : 2021-01-01 DOI: 10.33545/26638266.2021.v3.i1b.133
D. Pandurangaiah, Dr. GM Pradeep Kumar
Purpose: To compare accommodative convergence over accommodation (AC/A) ratio when Myopic patient changes from Spectacles to Contact lenses. Methods: A prospective, cross-sectional study group of 50 subjects and Myopic error from -0.75DS to - 6.00DS. The AC/A ratio was measured by two methods; the heterophoria method and the gradient method. Gradient method was measured by plus and minus Lenses technique. Heterophoria in near and distance was measured to calculate heterophoria method. Wilcoxon Signed Ranks Test was used to compare between two methods p value < 0.05. Result s : The mean AC/A ratio in Gradient method when using Soft Contact Lenses in comparison to Spectacles was: with+3(2.21, 2.24), and with-3(1.51,150) respectively. Although the AC/A ratio was less in amount with +3D lens in near and more in distance with -3D lens as compared to Spectacles, there were no significant differences found between the two (P:0.285 and P:0.317 respectively). The means of AC/A ratio as calculated by Heterophoria method was increased with soft contact lenses (5.97) as compared to spectacles (5.96) with no significant difference p: 0.317 Conclusion: No significant difference has been found for myope when changing from spectacles to contact lenses.
目的:比较近视患者配戴眼镜与隐形眼镜时的调节收敛与调节(AC/A)比。方法:采用前瞻性、横断面研究,50名受试者,近视误差在-0.75 ~ - 6.00DS之间。采用两种方法测量AC/A比值;暗差法和梯度法。梯度法采用正负透镜法测量。测量近处和远处的暗差,计算暗差法。两种方法间比较采用Wilcoxon sign rank检验,p值< 0.05。结果:与普通眼镜相比,梯度法使用软性隐形眼镜时的平均AC/A比分别为+3(2.21,2.24)和-3(1.51,150)。虽然与Spectacles相比,+3D镜头近处的AC/A比较少,而-3D镜头远处的AC/A比较多,但两者之间无显著差异(P分别为0.285和0.317)。软质隐形眼镜的AC/A比值平均值(5.97)高于普通眼镜(5.96),p值为0.317,差异无统计学意义。
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引用次数: 0
Microbiological profile and antimicrobial sensitivity pattern of culture positive bacterial keratitis: A prospective observational study 培养阳性细菌性角膜炎的微生物学特征和抗菌药物敏感性模式:一项前瞻性观察研究
Pub Date : 2021-01-01 DOI: 10.33545/26638266.2021.v3.i1b.70
A. Satish, M. DeborahPurushottam, A. Acharya
Background: Microbial keratitis is suppurative infection of cornea considered as emergency and potential threat to vision. Prompt diagnosis and treatment of microbial keratitis is required to prevent complication and blindness. So present study has been designed to determine bacteriological profile and sensitivity pattern of culture positive bacterial keratitis, risk factor associated it and treatment outcome.Material and Method: After enrolment of patients a detailed relevant history of patients regarding to mode of injury and predisposing factor were recorded and detailed clinical examination was done. Visual acuity of all patients was tested. Slit lamp biomicroscopy was performed and Corneal ulcer was examined properly. Under local anaesthesia with 4% lignocaine corneal scrap was taken from edge and base of ulcer. Sample was sent for gram stain, 10% KOH wet mount preparation, blood agar and Sabouraud's dextrose agar.Result: In present study out of 600 specimen 460(76.66%) patients were culture positive out of them 47.33% were fungal and remaining were bacterial(29.33%). Regarding bacteriological profile of culture positive corneal ulcer, we have observed that gram positive bacteria were common than gram negative. Among all staphylococcus aureus was common organism 54(30.68%).Discussion and Conclusion: From present study we can conclude that bacterial corneal ulcer is less common than funga ulcer. Regarding bacteriological profile of culture positive corneal ulcer, we have observed that gram positive bacteria were common than gram negative. Among all staphylococcus aureus was common organism followed by pseudomonas. Regarding sensitivity of common organism isolated staphylococcus was 100% sensitive to vancomycin and azithromycin, sensitivity to fluoroquinolones were from 60 % to 80 %. More than 80% pseudomonas was sensitive to fluoroquinolones and aminoglycosides. 77.27% patients were recovered at final follow up.
背景:微生物性角膜炎是一种角膜化脓性感染,被认为是一种紧急情况,对视力有潜在威胁。为了防止并发症和致盲,需要及时诊断和治疗微生物角膜炎。因此,本研究旨在确定培养阳性细菌性角膜炎的细菌学特征、敏感性模式、相关危险因素和治疗效果。材料与方法:患者入组后详细记录患者损伤方式及诱发因素的相关病史,并进行详细的临床检查。对所有患者进行视力检查。进行裂隙灯生物显微镜检查,并对角膜溃疡进行检查。在4%利多卡因局部麻醉下,从溃疡边缘和底部取角膜屑。样品送去革兰氏染色、10% KOH湿片制备、血琼脂和沙伯劳德葡萄糖琼脂。结果:本组600例标本中培养阳性460例(76.66%),其中真菌检出47.33%,细菌检出29.33%。关于培养阳性角膜溃疡的细菌学特征,我们观察到革兰氏阳性细菌比革兰氏阴性细菌多。金黄色葡萄球菌中常见菌54株(30.68%)。讨论与结论:从目前的研究结果来看,细菌性角膜溃疡的发病率低于真菌性角膜溃疡。关于培养阳性角膜溃疡的细菌学特征,我们观察到革兰氏阳性细菌比革兰氏阴性细菌多。其中以金黄色葡萄球菌最为常见,其次为假单胞菌。葡萄球菌对万古霉素和阿奇霉素的敏感性为100%,对氟喹诺酮类药物的敏感性为60% ~ 80%。80%以上假单胞菌对氟喹诺酮类药物和氨基糖苷类药物敏感。77.27%的患者在最后随访时恢复。
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引用次数: 0
Clinical profile of patients with anterior uveitis 前葡萄膜炎患者的临床分析
Pub Date : 2021-01-01 DOI: 10.33545/26638266.2021.V3.I1A.62
S. Km, N. Vijay
The anterior uveitis can be categorized as iritis, anterior cyclitis and iridocyclitis. It often causes a painful red eye. Patients with anterior uveitis complain of redness, photophobia, tearing and blurred vision. Acute anterior uveitis causes mild vision loss but still contributes significantly to the total burden. It causes vision loss both directly through inflammation and via complications such as macular edema, glaucoma, cataract, and others. A prospective clinical study was conducted. The material for this study included, 50 patients between age 20 and 80 years, attending outpatient department, Department of Ophthalmology with signs and symptoms of anterior uveitis. In the present study it was observed that most common presentation was acute anterior uveitis, accounting for 76%, then chronic 18% and only 6% of the patients had recurrent anterior uveitis. In the present study 45 (90%) patients had non granulomatous inflammation and in 5 (10%) patients it was granulomatous inflammation. Thus nongranulomatous inflammation was more common than granulomatous inflammation.
葡萄膜前炎可分为虹膜炎、前睫状体炎和虹膜睫状体炎。它通常会引起痛苦的红眼。前葡萄膜炎患者主诉为发红、畏光、流泪和视力模糊。急性前葡萄膜炎引起轻度视力丧失,但仍对总负担有显著贡献。它直接通过炎症和黄斑水肿、青光眼、白内障等并发症导致视力下降。进行前瞻性临床研究。本研究的材料包括50例年龄在20 ~ 80岁之间,就诊于眼科门诊的前葡萄膜炎症状和体征的患者。在本研究中,我们观察到最常见的表现是急性葡萄膜炎,占76%,其次是慢性18%,只有6%的患者复发性葡萄膜炎。在本研究中,45例(90%)患者有非肉芽肿性炎症,5例(10%)患者有肉芽肿性炎症。因此非肉芽肿性炎症比肉芽肿性炎症更常见。
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引用次数: 0
Evaluation of outcomes of cataract surgery in diabetic and non-diabetic patients 糖尿病与非糖尿病患者白内障手术的疗效评价
Pub Date : 2021-01-01 DOI: 10.33545/26638266.2021.v3.i1b.66
Apurva H. Suthar, Kaushal A. Modi
Background and Aim: Poor visual outcome after cataract surgery in diabetics associated with the severity of pre-existing retinopathy and diabetic maculopathy prior to the surgery. Higher incidence of diabetes in developing countries such as India necessitates an assessment of the outcome of cataract surgery in diabetic patients. Hence this study is planned to asses and compare outcome of cataract surgery in diabetics. Material and Methods: The present study was done to compare outcome of cataract surgery in 70 diabetics as compared to 70 non-diabetics attending department of Ophthalmology of tertiary care institute of Gujarat for the duration of one and half year. A prospective study was done Age, sex, surgical technique, follow up, pre- and postoperative best corrected visual acuity (BCVA) and post-op complications were evaluated. Results: The mean age group of patients in diabetic group was 55.7±6.5 and 58.3±6.4 in non-diabetic group. Out of 70 patients in the diabetic group, 42 had good glycaemic control (FBS:70-100mg/dl). Remaining 28 patients had high blood sugar levels (>100mg). Hypertension though the most frequent co-morbid disease in both the groups, it’s more frequent amongst diabetics as seen in this study, that is 26 compared with 16 of the nondiabetic patients. On comparing the pre-operative and post-operative visual acuity in both the groups the p value in diabetics as compared to in the Non-diabetic group was statistically significant. (p≤0.05) Conclusion: Pre-operative diabetic retinopathy status is a major determinant of post-operative visual recovery. Monitoring postoperative progression of diabetic retinopathy severity after uneventful intraocular lens implantation may enhance visual outcome. There is a higher incidence of post-operative complications among diabetics, which can be managed conservatively.
背景和目的:糖尿病患者白内障手术后视力差与术前已有视网膜病变和糖尿病黄斑病变的严重程度有关。印度等发展中国家的糖尿病发病率较高,因此有必要对糖尿病患者白内障手术的结果进行评估。因此,本研究计划评估和比较糖尿病患者白内障手术的结果。材料和方法:本研究比较了70名糖尿病患者和70名非糖尿病患者在古吉拉特邦三级保健研究所眼科接受白内障手术的结果,为期一年半。观察年龄、性别、手术方式、随访情况、术前、术后最佳矫正视力(BCVA)及术后并发症。结果:糖尿病组患者平均年龄为55.7±6.5岁,非糖尿病组患者平均年龄为58.3±6.4岁。在70例糖尿病患者中,42例血糖控制良好(FBS:70-100mg/dl)。其余28例患者血糖水平较高(>100mg)。高血压虽然是两组中最常见的合并症,但在糖尿病患者中更常见正如在这项研究中所看到的,有26人患高血压而非糖尿病患者只有16人患高血压。两组术前、术后视力比较,糖尿病组与非糖尿病组比较,p值有统计学意义。(p≤0.05)结论:术前糖尿病视网膜病变状态是影响术后视力恢复的重要因素。监测术后进展的糖尿病视网膜病变严重程度后,顺利人工晶状体植入术可提高视力的结果。糖尿病患者术后并发症发生率较高,可采取保守治疗。
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引用次数: 0
Assessment of binocular vision in kids with hearing loss 听力损失儿童双眼视力的评估
Pub Date : 2021-01-01 DOI: 10.33545/26638266.2021.v3.i1b.134
Dr. GM Pradeep Kumar, D. Pandurangaiah
Background: Hearing is the ability to perceive sound. A person is said to have hearing loss when he/she is not able to hear as well as someone with a normal hearing threshold of 25 dB or better in both ears. Binocular function plays an important role as it helps to coordinate both eyes. Methodology: A prospective study was conducted with 103 subjects. After taking permission authority and Hearing impairment school, consent was taken from participants. The comprehensive evaluation included demographic data, history of hearing impairment, refraction. Then binocular vision assessment (sensory, motor, accommodative, vergence tests) was done. Results: 103 children with a mean age of 14.36±3.07years were included in the study. 54% had a severe hearing impairment and 46% of children had a profound hearing impairment. 9.7% refractive error among hearing-impaired children. Myopia is 4%. Hyperopia is 1% and Astigmatism is 5%. NSBVA was found around 49% among HI children. Convergence excesses 20.4%, Convergence insufficiency 3.9%, Divergence excess 1%, Divergence Insufficiency 3.9%. Accommodative insufficiency 5.8% and Accommodative excess 13.6%. Conclusion: Non-strabismus binocular vision anomalies among profound and severe hearing-impaired subjects. So, it is important to consider binocular evaluation among hearing-impaired subjects.
背景:听觉是感知声音的能力。如果一个人的听力低于双耳正常听力阈值为25分贝或更高的人,那么他/她就被称为听力损失。双眼功能起着重要的作用,因为它有助于协调两只眼睛。方法:对103名受试者进行前瞻性研究。在获得许可机构和听力障碍学校后,获得参与者的同意。综合评估包括人口统计资料、听力障碍史、屈光。然后进行双眼视觉评估(感觉、运动、调节、收敛测试)。结果:103例患儿入组,平均年龄14.36±3.07岁。54%的儿童患有重度听力障碍,46%的儿童患有重度听力障碍。9.7%的听障儿童屈光不正。近视是4%。远视为1%,散光为5%。在HI儿童中发现NSBVA约占49%。收敛过度20.4%,收敛不足3.9%,发散过度1%,发散不足3.9%。调节不足5.8%,调节过剩13.6%。结论:重度和重度听障者非斜视双眼视力异常。因此,在听力受损的受试者中考虑双眼评价是很重要的。
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引用次数: 0
A study on management of anterior uveitis at a tertiary care hospital 某三级医院前葡萄膜炎的处理研究
Pub Date : 2021-01-01 DOI: 10.33545/26638266.2021.v3.i1b.63
S. Km, N. Vijay
A careful and detailed medical history is one of the keys to correct diagnosis in a patient with uveitis. It also provides information that may contribute to the choice of treatment indicated. The history-taking process should follow a structured approach and should include personal general information, chief complaint, past ocular and medical history, family history, review of systemic complaints and miscellaneous details on injury, surgery, migration and specific history on exposure to risk factors. A standard clinical proforma was filled in all cases, which included salient feature in history, visual acuity using Snellens visual acuity chart, clinical findings, laboratory investigations, and the final aetiology. All patients were examined under slit lamp. Details on disease severity, laterality, chronicity, ocular signs and associated systemic conditions were noted. In the present study all the 50 patients (100%) were treated with topical steroids and cycloplegics-mydriatics. Periocular steroid was given in 9 patients (18%) of which one had bilateral chronic anterior uveitis and received injections to both the eyes. Systemic steroids were used in 18 patients (36%), which included 6 patients of phacolytic uveitis, 5 herpetic uveitis patients, 3 patients of TB, 2 idiopathic and one each in leprosy and psoriatic patient. 13 patients (26%) received antiglaucoma therapy.
仔细详细的病史是正确诊断葡萄膜炎的关键之一。它还提供了可能有助于选择所指出的治疗的信息。病史采集过程应遵循有组织的方法,并应包括个人一般信息、主诉、既往眼病和病史、家族史、对全身疾患的审查以及有关损伤、手术、迁移和接触危险因素的具体历史的各种细节。所有病例均填写标准的临床表格,包括病史、Snellens视度表视力、临床表现、实验室检查和最终病因。所有患者均在裂隙灯下检查。详细记录疾病的严重程度、侧边性、慢性、眼部体征和相关的全身状况。在本研究中,所有50例患者(100%)均采用局部类固醇治疗和单眼麻痹-心肌病。9例患者(18%)接受眼周类固醇治疗,其中1例患有双侧慢性前葡萄膜炎,双眼均接受注射。全身性类固醇治疗18例(36%),其中溶解性葡萄膜炎6例,疱疹性葡萄膜炎5例,结核3例,特发性2例,麻风病和银屑病各1例。13例(26%)患者接受了抗青光眼治疗。
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引用次数: 0
Choroidal thickness in patients with different refractive status measured by spectral-domain optical coherence tomography 光谱域光学相干断层扫描测量不同折射状态患者脉络膜厚度
Pub Date : 2021-01-01 DOI: 10.33545/26638266.2021.v3.i1b.69
Farhat Abrar, Juhi Garg, Shashwat Singh, Kainat Chaudhary
Aim: To evaluate the choroidal thickness in patients with different refractive status measured by spectral-domain optical coherence tomography. Material and methods: This cross-sectional observational study consisted of 60 subjects, who visited the out-patient department of Ophthalmology, Chattrapati Shivaji Subharti Hospital, Meerut, India and were randomly selected over a period of 1 year. Subjects were classified into three groups based on refractive error: those with a +1 diopter or greater refractive power were assigned to the hyperopia group; those with a diopter lower than +1 and greater than –1 were assigned to the emmetropia group; and those with a –1 diopter or lower diopter were assigned to the myopia group. All patients underwent a clinical history taking and a complete ophthalmic examination. OCT scanning was performed using Optovue RTvue 100 which utilises spectral domain (SD)-OCT. The choroid was visualized by enhanced depth imaging (EDI) technique. Choroidal scans were obtained for all the eyes using enhanced depth imaging (EDI) using spectral-domain optical coherence tomography (SD-OCT). Data was recorded in excel sheet and subjected to statistical analysis. Results: Compared to emmetropic participants, myopic subjects had significantly thinner choroid in all the regions. Choroid of hyperopic subjects was significantly thicker than that of emmetropic subjects in most regions. Linear correlation testing revealed a close correlation between refractive error and choroidal thickness in all of the regions. Conclusion: High myopes have significantly thinner choroids than the emmetropic controls at all the retinal points studied, with the thinnest choroid at 1.5 mm nasal to the fovea.
目的:评价光谱域光学相干断层扫描对不同折射状态患者脉络膜厚度的影响。材料与方法:本横断面观察性研究随机选取60名在印度密鲁特Chattrapati Shivaji Subharti医院眼科门诊就诊的患者,时间为1年。根据屈光不正将受试者分为三组:屈光不正+1或以上的受试者被分为远视组;视屈光度< +1 > -1者为远视组;屈光度为-1或更低的人被分配到近视组。所有患者均接受了临床病史和完整的眼科检查。使用Optovue RTvue 100进行OCT扫描,该仪器利用光谱域(SD)-OCT。增强深度成像(EDI)技术显示脉络膜。使用光谱域光学相干断层扫描(SD-OCT)增强深度成像(EDI)获得所有眼睛的脉络膜扫描。数据以excel表格记录,并进行统计分析。结果:与非远视者相比,近视眼受试者在所有区域的脉络膜都明显变薄。远视受试者的脉络膜在大多数地区明显厚于正视受试者。线性相关测试显示,所有区域的屈光不正与脉络膜厚度密切相关。结论:高度近视眼视网膜各点的脉络膜均明显薄于正视对照,其中距中央窝1.5 mm处的脉络膜最薄。
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International Journal of Medical Ophthalmology
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