International Journal of Environmental Health Research最新文献

This study aimed to assess the antioxidant capacity, the insecticidal, feeding deterrence, repellent effects against Tribolium confusum of the essential oil (EO) and the organic extracts (ME) of Origanum vulgare. The chemical composition of the EO revealed the presence thirty-nine components dominated by carvacrol (81%). With respect to the EO, the ME acted as a potent free radical scavenger with IC50 values of 0.127 and 0.058 mg/mL, respectively. The EO exhibited the most significant toxicity compared to the ME with a mortality of 62 and 20% at 0.08 µL/insect after 24h whereas the EO expressed the highest repellency compared to the ME with a PR of 70 and 38% after 24h. As for feeding deterrence, both samples influenced all nutritional indexes. The findings found in this work might help in the promotion of oregano as natural antioxidant, antifeedant, repellent and insecticide as an alternative to conventional harmful ones.

Mounting epidemiology studies have reported the potential associations between ambient air pollution exposure and colorectal cancer (CRC). However, the genetic association between ambient air pollution and CRC remains unclear. Using the Genome-wide association study (GWAS) data from UK biobank, we explored the genetic association of CRC (5,657 cases and 372,016 controls) with four ambient air pollutants (PM_2.5, PM₁₀, NO₂, NO_x; n = 423,796 to 456,380) under the framework of Mendelian randomization (MR). Our results revealed a significant association between long-term NO₂ exposure (per 10 µg/m³) and increased CRC risk, with an odds ratio (OR) of 1.02 (95% confidence interval [CI]: 1.00-1.03), while no statistical association was found between CRC risk and the other air pollutants. Sensitivity analysis confirmed the robustness of the results. It is imperative to consider the impact of air pollution, particularly NO₂, in mitigating the risk of CRC.

Parents´ perceptions can influence their children´s mode of commuting to school. In this sense, the purposes of this study were to compare parental barriers towards active commuting to school (ACS) between Ecuadorian and Spanish children, and to analyze the associations between those barriers and the children's mode of commuting. Descriptive and comparative analyses were performed using Chi-square and T-student test. Associations were analyzed by several logistic regression models. Results showed that road safety is the main barrier for ACS, and that all the barriers are perceived as higher by Ecuadorian parents (p<0.001). It was also found that Ecuadorian children were less likely to be active when parents perceive greater total barriers (OR=0.15, CI=0.06, 0.40). Public policies should focus on reducing the parental barriers in order to increase ACS, specifically those related to road safety.

The widely believed Helicobacter pylori infection has never explained the birth-cohort phenomenon of peptic ulcers. Although numerous studies have observed that environmental factors are associated with peptic ulcers, their role in the disease has yet to be identified. A new etiological theory proposed that environmental factors cause peptic ulcers via inducing psychological stress. Starting from this etiology, an integration of the mortality rates caused by social and natural environmental factors reproduced a representative fluctuation curve in the birth-cohort phenomenon, where a causal role of environmental factors in peptic ulcers was hidden. The reproduced fluctuation curve revealed that multiple environmental factors caused the birth-cohort phenomenon by Superposition Mechanism, and the causal role of each individual environmental factor surfaced if the fluctuation curves in the birth-cohort phenomenon were properly differentiated. A full understanding of the birth-cohort phenomenon highlights the importance of environmental management in improving clinical outcomes, and suggests that the Superposition Mechanism is an indispensable methodological concept for life science and medicine.

The generation of faecal sludge (FS) in capitals and urban settings of African countries outpaces the available storage, emptying, transportation and treatment technologies. The low technology-based treatment systems for handling FS are preferable and widely adopted in the African context due to their less associated investment and operation costs. The waste stabilization ponds and constructed wetlands were principally developed as wastewater treatment systems however they are widely adopted for treating FS in urban settings of Africa. Less information is known about the efficiency of these systems in lowering FS pollutant concentrations to meet the design specifications and the allowable discharge limits. This paper reviewed the technical efficacy of waste stabilization ponds and the constructed wetlands in treating FS by evaluating the actual treatment efficiency data against the design efficiencies and the maximum allowable discharge limits. The review results revealed that these technologies are user-friendly although they fail to lower the solids concentrations to meet the design and maximum allowable discharge limits. This failure imposes extra costs on operation and maintenance due to the fast filling of solids in the systems hence leading to short-circuiting issues. So, studies on the adequate dewatering technologies of FS before entering the systems are needed.

This work aimed to evaluate the effect of different extraction solvents on the polyphenolic content, antioxidant and antibacterial activity of Pistacia lentiscus stems. The results obtained show that the extraction yield depends strongly on the polarity of the solvent and the extraction method. The ethanolic extract had the highest yield in both extraction methods investigated, namely Soxhlet (R = 9.89%) and cold maceration (R = 9.20%). The free radical scavenging activity of the extracts showed that the ethanolic extract had the highest antioxidant activity in both extraction methods with an IC₅₀ = 0.023 mg/mL (cold maceration) and an IC₅₀ = 0.034 mg/ml (Soxhlet). The HPLC analysis of the extracts indicates that gallic acid and catechin are the major phenolic compounds. The FTIR results showed that the shift of the stretching is responsible for O-H and C-H bonding. The GC-MS analysis revealed the presence of stearic acid and palmitic acid methyl ester as main compounds. The bacterial analysis of the extracts showed that the aqueous extract represents the most active one against Staphylococcus aureus and Pseudomonas aeruginosa; on the other hand, no antifungal activity was appreciated. Overall, the results indicate that the investigated extracts might be considered valuable sources of bioactive compounds.

This study investigates the PM2.5 bound metals using yearlong measurements at a regionally representative suburban site in the Northwest Indo-Gangetic Plain (NWIGP). The order of the measured annual average concentrations of PM2.5 bound metals is Fe > Zn > Ba > Sn > Pb > Cd > Ni > Mn > Cr > Li. Lithium bound to airborne PM2.5 has been reported for the first time in NWIGP. Ni (72.4 ng m-3) and Cd (36.9 ng m-3) have exceeded the acceptable limits set by NAAQS, India. Estimated the hazard quotient (HQ > 1) of Mn and hazard index (HI > 1) of measured metals exceeded the threshold limits indicating the potential non-carcinogenic health risk due to inhalation exposure of PM2.5 bound trace metals. Further, excessive lifetime cancer risk due to inhalation exposure to Cd, Ni and Cr was estimated and found to exceed the threshold limit set by the USEPA for adults and children.

Risk perception and use of personal protective equipment (PPE) in pesticide use were studied in 109 farmers of northern Greece. Farmers differed in the levels of pesticide risk perception, with 26.6% showing very low and low levels, 34.9% showing moderate levels, and 38.5% showing high and very high levels. Pesticide risk perception was positively correlated with education and large cultivated area, but negatively with age and non-farming as a main profession. Most farmers (82.6%) showed adequate use of PPE (mostly face mask and gloves). The use of PPE was positively correlated with education and risk perception, but negatively with age and non-farming as a main profession. Farmers with high levels of risk perception used 1.3 and 2.6 times more PPE items than those with moderate and low levels of risk perception, respectively. High education was a positive predictor, whereas main profession other than farming was a negative predictor of PPE use.

Previous studies on temperature and infectious diseases primarily focused on individual disease types, yielding inconsistent conclusions. This study collected monthly data on notifiable infectious disease cases and meteorological variables across 7 provinces in China from 2011 to 2019. A distributed lag nonlinear model was used to evaluate the association between ambient temperature and infectious diseases within each province, and random meta-analysis was applied to evaluate the pooled effect. Extreme hot temperature (the 97.5th percentile) was positively associated with the risk of respiratory infectious diseases with the relative risk (RR) of 1.45 (95%CI: 1.01-2.08). Conversely, extreme cold temperature (the 2.5th percentile) was negatively associated with intestinal infectious diseases and zoonotic diseases and vector-borne diseases, reporting RRs of 0.43 (95%CI: 0.30-0.60) and 0.46 (95%CI: 0.38-0.57), respectively. This study described the nonlinear association between ambient temperature and infectious diseases with different transmission routes, informing comprehensive prevention and control strategies for temperature-related infectious diseases.

The main aim of this study is to quantitatively evaluate the differences, in terms of exposure to PM (particulate matter), between WFO (working-from-office) and WFH (working-from-home) conditions. Two measurement surveys were performed: a long-term and a short-term campaign, focused on the monitoring of personal exposure to size-fractionated PM in these different working conditions. Results of the long-term campaign show that the WFH subject is exposed to higher (up to 4 times) PM concentration, compared to the WFO subject. Specific activities performed by the subjects impacted their exposure concentrations, even if the most relevant contribution to total exposure was made by desk work. Results of the short-term campaign indicate that the subjects can be divided into two groups: subjects most exposed during the WFH mode (HE_H - Higher_Exposure_Home) and subjects most exposed during the WFO mode (HE_O - Higher_Exposure_Office). HE_H group is exposed to levels of pollutants up to 4 times higher in the domestic than in the office environment, during the moment of desk work. The HE_O group is exposed to higher (double) concentration levels during desk work during the WFO day. Considering the possible growing trend towards remote work it is important to evaluate these "new domestic offices" comprehensively.