Green exercise, defined as physical activity in natural settings, shows promise for enhancing exercise participation and improving health. This systematic review aimed to assess the effectiveness of green exercise in people with chronic conditions. Seven electronic databases were searched and of the 7801 screened articles, 14 trials met the inclusion criteria. Green exercise was a safe and well-tolerated intervention, with low drop-out levels. It was found to positively affect participants' quality of life in three studies and mental health in four studies. Compared to non-exercise groups, green exercise significantly improved physical and mental health in patients with breast cancer, COPD, cardiovascular disease risk, chronic low back pain, obesity, and diabetes. However, it had no impact on the physical health of stroke patients or the cognitive performance of those with ADHD. Green exercise appears to be a safe intervention that can improve various chronic health issues.
{"title":"The effects of green exercise on the mental and physical health of people with chronic conditions: a systematic review.","authors":"Aristi Tsokani, Vasiliki Stefanouli, Nele Adriaenssens, Athanasios Kotsakis, Eleni Kapreli, Nikolaos Strimpakos","doi":"10.1080/09603123.2024.2391991","DOIUrl":"https://doi.org/10.1080/09603123.2024.2391991","url":null,"abstract":"<p><p>Green exercise, defined as physical activity in natural settings, shows promise for enhancing exercise participation and improving health. This systematic review aimed to assess the effectiveness of green exercise in people with chronic conditions. Seven electronic databases were searched and of the 7801 screened articles, 14 trials met the inclusion criteria. Green exercise was a safe and well-tolerated intervention, with low drop-out levels. It was found to positively affect participants' quality of life in three studies and mental health in four studies. Compared to non-exercise groups, green exercise significantly improved physical and mental health in patients with breast cancer, COPD, cardiovascular disease risk, chronic low back pain, obesity, and diabetes. However, it had no impact on the physical health of stroke patients or the cognitive performance of those with ADHD. Green exercise appears to be a safe intervention that can improve various chronic health issues.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142017370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-20DOI: 10.1080/09603123.2024.2393431
Yoon Young Choi, Kyeong Hee Lee
We investigated the association between ambient air pollutant exposure and periodontal health using data from 17,271 adults in the Korea National Health and Nutrition Examination Survey (2012-2015). Participants' periodontal status was categorized based on their community periodontal index (CPI) scores. Using multiple logistic regression models, we examined the relationship between air pollutant levels and poor periodontal status at various lag periods. After adjusting for potential confounders, PM10 exposure was associated with a poor periodontal status (short-term: 0-1 and 0-2 lag days; medium-term: 0-1 and 0-2 lag months). SO2 exposure showed similar associations (short-term, 0-2 to 0-7 lag days; medium-term, 0-4 to 0-6 lag months). Only increased medium-term O3 exposure (0-2 to 0-6 lag months) was associated with a poor periodontal status. NO2 exposure was inversely associated with poor periodontal status for both short- and medium-term durations.
{"title":"Short- and medium-term exposure to ambient air pollution and periodontal status.","authors":"Yoon Young Choi, Kyeong Hee Lee","doi":"10.1080/09603123.2024.2393431","DOIUrl":"https://doi.org/10.1080/09603123.2024.2393431","url":null,"abstract":"<p><p>We investigated the association between ambient air pollutant exposure and periodontal health using data from 17,271 adults in the Korea National Health and Nutrition Examination Survey (2012-2015). Participants' periodontal status was categorized based on their community periodontal index (CPI) scores. Using multiple logistic regression models, we examined the relationship between air pollutant levels and poor periodontal status at various lag periods. After adjusting for potential confounders, PM<sub>10</sub> exposure was associated with a poor periodontal status (short-term: 0-1 and 0-2 lag days; medium-term: 0-1 and 0-2 lag months). SO<sub>2</sub> exposure showed similar associations (short-term, 0-2 to 0-7 lag days; medium-term, 0-4 to 0-6 lag months). Only increased medium-term O<sub>3</sub> exposure (0-2 to 0-6 lag months) was associated with a poor periodontal status. NO<sub>2</sub> exposure was inversely associated with poor periodontal status for both short- and medium-term durations.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142008701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-20DOI: 10.1080/09603123.2024.2392947
{"title":"Correction.","authors":"","doi":"10.1080/09603123.2024.2392947","DOIUrl":"https://doi.org/10.1080/09603123.2024.2392947","url":null,"abstract":"","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142004135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-19DOI: 10.1080/09603123.2024.2391465
Habibeh Mashayekhi-Sardoo, Samaneh Sepahi, Adel Ghorani-Azam, Hedyeh Askarpour, Thomas P Johnston, Amirhossein Sahebkar
Microplastics and nanoplastics (MNPs) are present in urban dust and the aquatic environments of industrialized cities. MNPs in the human body accumulate in the lymphoid follicles, Peyer's patches of the gastrointestinal tract, and pulmonary vascular endothelial cells, which slowly result in toxicity. Since previous studies introduced curcumin as a natural protective agent against environmental toxins, we reviewed preclinical studies that had used curcumin to protect organs or cells from toxicity secondary to exposure to MNPs. It was found that exposure to MNPs resulted in osteolysis, immunotoxicity, thyroid disturbances, nephrotoxicity, neurotoxicity, hepatotoxicity, pulmonary toxicity, gastrointestinal toxicity, cardiovascular toxicity, and especially endocrine, and reproductive toxicity. Nevertheless, except for one study reviewed, curcumin restored all oxidative and histopathological damages induced by MNPs to normal due to curcumin's inherent antioxidant, antiapoptotic, anti-inflammatory, and anti-proliferative properties.
{"title":"Protective effect of curcumin against microplastic and nanoplastics toxicity.","authors":"Habibeh Mashayekhi-Sardoo, Samaneh Sepahi, Adel Ghorani-Azam, Hedyeh Askarpour, Thomas P Johnston, Amirhossein Sahebkar","doi":"10.1080/09603123.2024.2391465","DOIUrl":"https://doi.org/10.1080/09603123.2024.2391465","url":null,"abstract":"<p><p>Microplastics and nanoplastics (MNPs) are present in urban dust and the aquatic environments of industrialized cities. MNPs in the human body accumulate in the lymphoid follicles, Peyer's patches of the gastrointestinal tract, and pulmonary vascular endothelial cells, which slowly result in toxicity. Since previous studies introduced curcumin as a natural protective agent against environmental toxins, we reviewed preclinical studies that had used curcumin to protect organs or cells from toxicity secondary to exposure to MNPs. It was found that exposure to MNPs resulted in osteolysis, immunotoxicity, thyroid disturbances, nephrotoxicity, neurotoxicity, hepatotoxicity, pulmonary toxicity, gastrointestinal toxicity, cardiovascular toxicity, and especially endocrine, and reproductive toxicity. Nevertheless, except for one study reviewed, curcumin restored all oxidative and histopathological damages induced by MNPs to normal due to curcumin's inherent antioxidant, antiapoptotic, anti-inflammatory, and anti-proliferative properties.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142004136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Given the increasing occurrence of invasive fungal infections and the limited efficacy of modern antifungal medications, it is crucial to disseminate information regarding the potential sources of nosocomial mycoses through the One Health approach. This study investigated the presence and antifungal susceptibility of fungi in biofilm and water samples obtained from the drinking water distribution system (DWDS) of hospitals. The positivity rate for fungi in biofilm and water samples was 41% and 9%, respectively, with Aspergillus species, a significant causative agent of nosocomial mycoses, being the predominant fungi identified. Analysis of antifungal susceptibility test revelead a comparable resistance profile between some isolated species from the DWDS and those reported for certain clinical samples. While further research is required to determine the specific contribution of waterborne fungi to nosocomial fungal infections, our results emphasize the importance of controlling biofilm formation within DWDSs, particularly in high-risk hospital wards.
{"title":"Fungal presence and health implications in hospital water systems.","authors":"Soudabeh Ghodsi, Mahnaz Nikaeen, Shima Aboutalebian, Hossein Mirhendi","doi":"10.1080/09603123.2024.2391470","DOIUrl":"https://doi.org/10.1080/09603123.2024.2391470","url":null,"abstract":"<p><p>Given the increasing occurrence of invasive fungal infections and the limited efficacy of modern antifungal medications, it is crucial to disseminate information regarding the potential sources of nosocomial mycoses through the One Health approach. This study investigated the presence and antifungal susceptibility of fungi in biofilm and water samples obtained from the drinking water distribution system (DWDS) of hospitals. The positivity rate for fungi in biofilm and water samples was 41% and 9%, respectively, with <i>Aspergillus</i> species, a significant causative agent of nosocomial mycoses, being the predominant fungi identified. Analysis of antifungal susceptibility test revelead a comparable resistance profile between some isolated species from the DWDS and those reported for certain clinical samples. While further research is required to determine the specific contribution of waterborne fungi to nosocomial fungal infections, our results emphasize the importance of controlling biofilm formation within DWDSs, particularly in high-risk hospital wards.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141987922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-16DOI: 10.1080/09603123.2024.2382905
Leila Motaghi, Nabiollah Mansouri, Farideh Atabi, Mohammad Hassan Vahidnia
Long-term exposure to Volatile Organic Compounds (VOCs) is a health risk for citizens. In this study, the cumulative health risk of exposure to VOCs in Tehran was assessed by investigating the concentration of these pollutants in ambient air in a five-year period. Health risk assessment was calculated by the quantitative method and the carcinogenic risk level was determined using the lifetime carcinogenic risk (LCR) method. The average concentration of benzene, toluene, ortho-xylene, and ethylbenzene was 1.4-1.8, 4.8-5.4, 5-6.5, and 3.6-4 ppb, respectively. Although HQ was not greater than 1, but it was very close in the case of benzene, ortho-xylene, meta-xylene, and para-xylene. Benzene and ethylbenzene had the largest effect in the assessed health risk. So the long-term exposure of Tehran citizens to VOCs has serious health consequences for them, which could be different according to the exposure time and spatial variations.
{"title":"Investigation of the spatial variation of ambient air VOCs and their effects on the health risk caused by long-term exposure in urban area.","authors":"Leila Motaghi, Nabiollah Mansouri, Farideh Atabi, Mohammad Hassan Vahidnia","doi":"10.1080/09603123.2024.2382905","DOIUrl":"https://doi.org/10.1080/09603123.2024.2382905","url":null,"abstract":"<p><p>Long-term exposure to Volatile Organic Compounds (VOCs) is a health risk for citizens. In this study, the cumulative health risk of exposure to VOCs in Tehran was assessed by investigating the concentration of these pollutants in ambient air in a five-year period. Health risk assessment was calculated by the quantitative method and the carcinogenic risk level was determined using the lifetime carcinogenic risk (LCR) method. The average concentration of benzene, toluene, ortho-xylene, and ethylbenzene was 1.4-1.8, 4.8-5.4, 5-6.5, and 3.6-4 ppb, respectively. Although HQ was not greater than 1, but it was very close in the case of benzene, ortho-xylene, meta-xylene, and para-xylene. Benzene and ethylbenzene had the largest effect in the assessed health risk. So the long-term exposure of Tehran citizens to VOCs has serious health consequences for them, which could be different according to the exposure time and spatial variations.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141987923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Air pollutants are associated with potentially toxic metals (PTMs) and natural and/or artificial radionuclides, which can pose a major threat to human and environmental health. Pollens can be utilized as a bioindicator to determine the level of air pollution in urban areas. In this study, the concentrations of PTMs and natural radionuclides in 35 airborne pollen samples of 22 species belonging to Pinaceae, Cupressaceae, Araucariaceae, Betulaceae, Salicaceae, and Oleaceae families grown in different urban areas in Turkey were determined using an energy-dispersive X-ray fluorescence spectrometry. For the first time, non-carcinogenic and radiologic health risk assessments for adults were done, estimating hazard index (HI) and annual effective dose (AED), respectively. The concentrations of Fe, Mn, Zn, Ti, Sr, Cu, Ni, Co, Cr, V and Pb analyzed in airborne pollen samples varied from 52.1 to 3078.0, 26.1 to 159.6, 15.6 to 199.7, 9.1 to 282.2, 1.0 to 128.4, 5.0 to 40.1, 5.4 to 23.6, 40K (595.8), 232Th (5.2) and 238U (11.8), respectively. All HI and AED values revealed a very low non-carcinogenic and radiological health risk due to exposure to all PTMs and radionuclides in the pollen samples studied.
{"title":"Determination of potentially toxic metals and natural radionuclides in airborne pollens produced different urban environments in Turkey and health risk assessment.","authors":"Şeref Turhan, Talip Çeter, Ergin Murat Altuner, Serhat Karabıcak, Selin Çeter, Oktay Bıyıklıoğlu, Şeymanur Aktaş, Aslı Kurnaz","doi":"10.1080/09603123.2024.2391460","DOIUrl":"https://doi.org/10.1080/09603123.2024.2391460","url":null,"abstract":"<p><p>Air pollutants are associated with potentially toxic metals (PTMs) and natural and/or artificial radionuclides, which can pose a major threat to human and environmental health. Pollens can be utilized as a bioindicator to determine the level of air pollution in urban areas. In this study, the concentrations of PTMs and natural radionuclides in 35 airborne pollen samples of 22 species belonging to Pinaceae, Cupressaceae, Araucariaceae, Betulaceae, Salicaceae, and Oleaceae families grown in different urban areas in Turkey were determined using an energy-dispersive X-ray fluorescence spectrometry. For the first time, non-carcinogenic and radiologic health risk assessments for adults were done, estimating hazard index (HI) and annual effective dose (AED), respectively. The concentrations of Fe, Mn, Zn, Ti, Sr, Cu, Ni, Co, Cr, V and Pb analyzed in airborne pollen samples varied from 52.1 to 3078.0, 26.1 to 159.6, 15.6 to 199.7, 9.1 to 282.2, 1.0 to 128.4, 5.0 to 40.1, 5.4 to 23.6, <LD to 11.3, 1.6 to 26.6, <LD to 11.1 and <LD to 5.7 mg/kg, respectively. The average concentrations of K (2%), Th (1.3 mg/kg) and U (1.0 mg/kg) were converted into the activity concentrations (in Bq/kg) of <sup>40</sup>K (595.8), <sup>232</sup>Th (5.2) and <sup>238</sup>U (11.8), respectively. All HI and AED values revealed a very low non-carcinogenic and radiological health risk due to exposure to all PTMs and radionuclides in the pollen samples studied.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141971095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-13DOI: 10.1080/09603123.2024.2390479
Norin Binta Salsabila, Juliana Jalaludin, Nur Faseeha Suhaimi, Wan Nurdiyana Wan Mansor, Arif Sumantri
The study examines the relationship between air quality, meteorological factors, and COVID-19 cases in Cheras, Kuala Lumpur, and Kelapa Gading, North Jakarta. Analyzing data from 2020 and 2021, the research found notable correlations: COVID-19 cases in Cheras were positively associated with relative humidity (RH) and carbon monoxide (CO) but negatively with ozone (O₃) and RH in different years. In Kelapa Gading, COVID-19 cases were positively correlated with pollutants like sulfur dioxide (SO₂) and CO, while ambient temperature (AT) showed a negative correlation. The enforcement of social restrictions notably reduced air pollution, affecting COVID-19 spread. Predictive models for PM2.5 levels using robust regression techniques showed strong performance in Kuala Lumpur (R² > 0.9) but exhibited overfitting tendencies in Jakarta, suggesting the need for a longer study period for more accurate results.
{"title":"Predictions of PM<sub>2.5</sub> using air pollutants and meteorological factors with COVID-19 cases in Malaysia and Indonesia: a comparative study using feature selection and robust regression.","authors":"Norin Binta Salsabila, Juliana Jalaludin, Nur Faseeha Suhaimi, Wan Nurdiyana Wan Mansor, Arif Sumantri","doi":"10.1080/09603123.2024.2390479","DOIUrl":"https://doi.org/10.1080/09603123.2024.2390479","url":null,"abstract":"<p><p>The study examines the relationship between air quality, meteorological factors, and COVID-19 cases in Cheras, Kuala Lumpur, and Kelapa Gading, North Jakarta. Analyzing data from 2020 and 2021, the research found notable correlations: COVID-19 cases in Cheras were positively associated with relative humidity (RH) and carbon monoxide (CO) but negatively with ozone (O₃) and RH in different years. In Kelapa Gading, COVID-19 cases were positively correlated with pollutants like sulfur dioxide (SO₂) and CO, while ambient temperature (AT) showed a negative correlation. The enforcement of social restrictions notably reduced air pollution, affecting COVID-19 spread. Predictive models for PM<sub>2.5</sub> levels using robust regression techniques showed strong performance in Kuala Lumpur (R² > 0.9) but exhibited overfitting tendencies in Jakarta, suggesting the need for a longer study period for more accurate results.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141971097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-12DOI: 10.1080/09603123.2024.2390474
Byung-Keun Kim, Hwan-Cheol Kim, Dong-Wook Lee, Young-Hee Nam, Da Woon Sim, Youngsoo Lee, Ji-Su Shim, Min-Suk Yang, Min-Hye Kim, So Ri Kim, Sang-Heon Kim, Young-Il Koh, Heung-Woo Park
This study aimed to determine the effects of indoor environment (IE) and outdoor air pollutants (OAPs) in residential areas on acute exacerbation (AE) in patients with severe asthma. A total of 115 participants were recruited. To characterize IE, we used structured questionnaires and estimated OAP concentrations using a land-use regression model. Participants who were exposed to passive smoking and lived in houses where the kitchen and living room were not separated showed a significantly higher rate of AE (p = 0.014 and 0.0016, respectively). The mean concentration of PM2.5 in residential areas during the last 3 years was significantly higher in participants with AE than that in those without AE (19.8 ± 3.1 vs. 21.0 ± 2.5 µg/m3, p = 0.033). Moreover, the serum level of 8-hydroxy-2'-deoxyguanosine significantly increased in participants with AE compared to those without AE (56.9 ± 30.0 vs. 94.7 ± 44.5 ng/mL, p = 0.0047) suggesting enhanced oxidative stress in those with AE.
{"title":"Effects of indoor environments and outdoor air pollutants in residential areas on acute exacerbation in patients with severe asthma.","authors":"Byung-Keun Kim, Hwan-Cheol Kim, Dong-Wook Lee, Young-Hee Nam, Da Woon Sim, Youngsoo Lee, Ji-Su Shim, Min-Suk Yang, Min-Hye Kim, So Ri Kim, Sang-Heon Kim, Young-Il Koh, Heung-Woo Park","doi":"10.1080/09603123.2024.2390474","DOIUrl":"https://doi.org/10.1080/09603123.2024.2390474","url":null,"abstract":"<p><p>This study aimed to determine the effects of indoor environment (IE) and outdoor air pollutants (OAPs) in residential areas on acute exacerbation (AE) in patients with severe asthma. A total of 115 participants were recruited. To characterize IE, we used structured questionnaires and estimated OAP concentrations using a land-use regression model. Participants who were exposed to passive smoking and lived in houses where the kitchen and living room were not separated showed a significantly higher rate of AE (<i>p</i> = 0.014 and 0.0016, respectively). The mean concentration of PM<sub>2.5</sub> in residential areas during the last 3 years was significantly higher in participants with AE than that in those without AE (19.8 ± 3.1 <i>vs</i>. 21.0 ± 2.5 µg/m<sup>3</sup>, <i>p</i> = 0.033). Moreover, the serum level of 8-hydroxy-2'-deoxyguanosine significantly increased in participants with AE compared to those without AE (56.9 ± 30.0 <i>vs</i>. 94.7 ± 44.5 ng/mL, <i>p</i> = 0.0047) suggesting enhanced oxidative stress in those with AE.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141971096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-07DOI: 10.1080/09603123.2024.2384963
Edoardo Miotto, Anna Maria Tartaglione, Ivano Iavarone, Laura Ricceri, Amerigo Zona, Alessandra Ceccarini, Sabrina Rossi, Lucia Fazzo
Mismanagement of hazardous waste (HW) causes severe threats to ecosystems and human health. We conducted a systematic literature review and evaluated the evidence regarding the association between residential exposure to HW and childhood neurobehavioral effects. We consulted international agencies websites and conducted a search on MEDLINE and EMBASE databases by applying a "Population-Exposure-Comparator-Outcome" question. The evidence evaluation, based on the quality of the studies and their concordance, was graded in sufficient/limited/inadequate. Documents from international agencies were not found. Of the seventy-five studies screened, nine met the eligibility criteria. Studies agree on the association between residential exposure to HW sites and negative neurodevelopmental effects. The evidence of the association was attributed limited to cognitive and behavioral outcomes, and inadequate to Autism Spectrum Disorder. The evidence was evaluated sufficient for HW sites releasing lead and cognitive disorders. Residential exposure to unsafe HW sites may contribute to childhood neurobehavioral alterations. It is urgent to implement environmental remediation of contaminated sites and counteracting illegal and unsafe HW management practices.
{"title":"Neurodevelopmental outcomes in children living near hazardous waste sites: a systematic review.","authors":"Edoardo Miotto, Anna Maria Tartaglione, Ivano Iavarone, Laura Ricceri, Amerigo Zona, Alessandra Ceccarini, Sabrina Rossi, Lucia Fazzo","doi":"10.1080/09603123.2024.2384963","DOIUrl":"10.1080/09603123.2024.2384963","url":null,"abstract":"<p><p>Mismanagement of hazardous waste (HW) causes severe threats to ecosystems and human health. We conducted a systematic literature review and evaluated the evidence regarding the association between residential exposure to HW and childhood neurobehavioral effects. We consulted international agencies websites and conducted a search on MEDLINE and EMBASE databases by applying a \"Population-Exposure-Comparator-Outcome\" question. The evidence evaluation, based on the quality of the studies and their concordance, was graded in sufficient/limited/inadequate. Documents from international agencies were not found. Of the seventy-five studies screened, nine met the eligibility criteria. Studies agree on the association between residential exposure to HW sites and negative neurodevelopmental effects. The evidence of the association was attributed limited to cognitive and behavioral outcomes, and inadequate to Autism Spectrum Disorder. The evidence was evaluated sufficient for HW sites releasing lead and cognitive disorders. Residential exposure to unsafe HW sites may contribute to childhood neurobehavioral alterations. It is urgent to implement environmental remediation of contaminated sites and counteracting illegal and unsafe HW management practices.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141897400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}