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Chronic obstructive pulmonary disease attributable to air pollution in the South Asian countries: global burden of disease study 1990 - 2019. 南亚国家空气污染导致的慢性阻塞性肺病:1990-2019 年全球疾病负担研究。
IF 2.2 4区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2024-10-06 DOI: 10.1080/09603123.2024.2412141
Dipak Rana, Bishwajit Ghose

This study investigates the burden of COPD attributable to air pollution in South Asia using data from the Global Burden of Disease Study from 1990 to 2019. Method Data for this study were obtained from the Global Burden of Disease Study 2019. The burden was measured in terms of death, disability-adjusted life years (DALYs), and Years of life lost (YLLs). Results Since 1990, several countries in South Asia registered substantial declines in mortality rates attributed to COPD, ranging from -37.47% in Pakistan to -66.25% in Bangladesh. Similar trends were observed for DALYs and YLLs as well, which have potentially contributed to a considerable decrease in mortality rates at the regional level (-43.13%) compared to a 32.59% decline in Low SDI and 56.87% decline globally. Conclusion Despite significant declines since 1990, the burden of COPD attributable to air pollution reductions in the South Asian region's rates remains alarmingly high.

本研究利用 1990 年至 2019 年《全球疾病负担研究》的数据,调查了南亚因空气污染造成的慢性阻塞性肺病负担。方法 本研究的数据来自《2019 年全球疾病负担研究》。负担以死亡、残疾调整寿命年数(DALYs)和生命损失年数(YLLs)来衡量。结果 自 1990 年以来,南亚一些国家的慢性阻塞性肺病死亡率大幅下降,从巴基斯坦的-37.47% 到孟加拉国的-66.25% 不等。在残疾调整寿命年数和年均寿命年数方面也观察到类似的趋势,这有可能导致该地区的死亡率大幅下降(-43.13%),而低SDI下降了32.59%,全球下降了56.87%。结论 尽管自 1990 年以来慢性阻塞性肺病的发病率大幅下降,但南亚地区因空气污染导致的慢性阻塞性肺病发病率仍然高得惊人。
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引用次数: 0
Association between outdoor artificial light at night and low birth weight in California. 加利福尼亚州夜间室外人造光与出生体重不足之间的关系。
IF 2.2 4区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2024-10-06 DOI: 10.1080/09603123.2024.2412137
Kwadwo Boakye, Ayodeji Iyanda, Emmanuel Asante, Joseph Oppong

Artificial light at night (ALAN) is a growing environmental issue associated with adverse health consequences, but the association with low birth weight remains unknown. We aim to explore associations between outdoor ALAN and low birth weight across 7,808 census tracts in California. We use data from the California Communities Environmental Health Screening Tool (CalEnviroScreen) at the census tract level. VIIRS Nighttime Day/Night Band Composites Version 1 dataset within the Google Earth Engine platform was used to assess outdoor ALAN. Multivariable linear regression was used to analyze the data. Our findings showed that an interquartile range increase in outdoor ALAN resulted in an increase of 0.42% (95% CI: 0.37, 0.46) in low birth weight rate on average, after adjusting for all potential covariates. The results demonstrate a significant association between outdoor ALAN and low birth weight. These associations remained consistent in sensitivity analyses.

夜间人造光(ALAN)是一个与不良健康后果相关的日益严重的环境问题,但它与低出生体重之间的关系仍然未知。我们旨在探讨加利福尼亚州 7,808 个人口普查区中室外 ALAN 与出生体重不足之间的关系。我们使用的数据来自加州社区环境健康筛查工具(CalEnviroScreen)的普查区级数据。谷歌地球引擎平台中的 VIIRS 夜间昼/夜波段复合版本 1 数据集用于评估室外 ALAN。采用多变量线性回归分析数据。我们的研究结果表明,在对所有潜在的协变量进行调整后,室外 ALAN 在四分位数范围内的增加导致低出生体重率平均增加 0.42%(95% CI:0.37,0.46)。结果表明,室外 ALAN 与低出生体重之间存在明显关联。这些关联在敏感性分析中保持一致。
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引用次数: 0
Evaluating metal levels and potential health risks of nail polish brands on the Ghanaian market. 评估加纳市场上指甲油品牌的金属含量和潜在健康风险。
IF 2.2 4区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2024-10-04 DOI: 10.1080/09603123.2024.2410457
Maame Tabitha Kuukua Osiban-Fordjour, Caroline Rosemyya Kwawu, Marian Asantewah Nkansah

Research has shown possible existence of heavy metals in cosmetic products, as they are known to impact colour. Assessments have been carried out on selected brands of nail polishes on Ghanaian markets in the Ashanti Region, for levels of six metals, i.e., lead (Pb), cadmium (Cd), aluminium (Al), chromium (Cr), manganese (Mn), and copper (Cu). A total of twenty (20) nail polish samples were analysed using the Atomic Absorption Spectrophotometer model nova 400P. The highest concentrations determined were Al (77.50 mg/L), Cu (2.126 mg/L), and Cr (25.66 mg/L). The levels of Pb, Cd, and Mn were all below detection limit. All samples analysed were below the WHO permissible limits, making them safe for use. Health risks associated with intake of these metals via dermal route, inhalation, and ingestion are evaluated, Hazard Quotient (HQ) and Hazard Index (HI) are below unity, suggesting no potential health risks associated with their use.

研究表明,化妆品中可能含有重金属,因为众所周知,重金属会影响颜色。我们对加纳阿散蒂地区市场上某些品牌的指甲油进行了六种金属含量的评估,即铅(Pb)、镉(Cd)、铝(Al)、铬(Cr)、锰(Mn)和铜(Cu)。使用 nova 400P 型原子吸收分光光度计对二十(20)份指甲油样本进行了分析。测定的最高浓度为铝(77.50 毫克/升)、铜(2.126 毫克/升)和铬(25.66 毫克/升)。铅、镉和锰的含量均低于检测限。分析的所有样本均低于世界卫生组织允许的限值,因此可以安全使用。经评估,通过皮肤途径、吸入和摄入这些金属对健康造成的风险、危害商数(HQ)和危害指数(HI)均低于统一值,表明使用这些金属不会对健康造成潜在风险。
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引用次数: 0
Phytochemical analysis and in vitro biological activity assessment of extracts from Micromeria myrtifolia. 小叶紫檀提取物的植物化学分析和体外生物活性评估
IF 2.2 4区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2024-10-03 DOI: 10.1080/09603123.2024.2409829
Taskın T, Oksuz M, Rayaman E, Ermanoglu M, Taskın D, Acar A G, Kılıç Ö, Çalışkan Salihi E, Yılmaz Nur B, Elçioğlu Hk

In this study, the antioxidant capacity, the effect on anti-acetylcholinesterase and anti-urease enzyme inhibition, and kidney stone-reducing effects of different extracts from M.myrtifolia. In addition, the phytochemical content of the bioactive methanol extract was analyzed by HPLC-DAD. The methanol extract showed strong DPPH (IC50:0.036 mg/mL) radical scavenging, Cu (II) ion (6.535 mmTroloxE) and Fe3+ (6.476 FeSO4) ion reducing antioxidant activity compared to other extracts. The methanol extract contained the highest amount of phenolic (400 mgGAE) and flavonoid (2.519 QuE) compounds. Moreover, the methanol extract had significant anticholinesterase (78.935%), anti-urease (71.014%) and calcium oxalate anti-crystallization (18.22%, 37.427%) activities. The findings show that all extracts exhibited varying amounts of antibacterial activity against Staphylococcus aureus. The bioactive methanol extract contained rosmarinic acid (31.35 µg), quercetin (12.99 µg) and chlorogenic acid (3.55 µg). The analyzed compounds are thought to contribute significantly to the pharmacological effect of the methanol extract.

本研究对M.myrtifolia不同提取物的抗氧化能力、抗乙酰胆碱酯酶和抗尿酸酶抑制作用以及肾结石还原作用进行了研究。此外,还采用 HPLC-DAD 分析了具有生物活性的甲醇提取物的植物化学成分含量。与其他提取物相比,甲醇提取物具有很强的清除 DPPH(IC50:0.036 mg/mL)自由基、Cu (II) 离子(6.535 mmTroloxE)和 Fe3+ (6.476 FeSO4)离子还原的抗氧化活性。甲醇提取物中的酚类化合物(400 mgGAE)和黄酮类化合物(2.519 QuE)含量最高。此外,甲醇提取物还具有显著的抗胆碱酯酶(78.935%)、抗尿酸盐酶(71.014%)和草酸钙抗结晶(18.22%、37.427%)活性。研究结果表明,所有提取物都对金黄色葡萄球菌具有不同程度的抗菌活性。具有生物活性的甲醇提取物中含有迷迭香酸(31.35 µg)、槲皮素(12.99 µg)和绿原酸(3.55 µg)。所分析的化合物被认为对甲醇提取物的药理作用有重大贡献。
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引用次数: 0
Exploring natural herbs: their role in treating male infertility, enhancing sexual desire and addressing urological disorders. 探索天然草药:它们在治疗男性不育、提高性欲和解决泌尿系统疾病方面的作用。
IF 2.2 4区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2024-10-03 DOI: 10.1080/09603123.2024.2408417
Abir Nasir, Erdal Yabalak

Infertility affects 8-12% of couples globally, with male factors contributing to around 40% of cases. Common male infertility issues include erectile dysfunction (ED) and low sperm count or quality, which account for over 90% of cases. These problems often result from anatomical, hormonal, or genetic abnormalities. This review focuses on natural aphrodisiac herbs commonly used to address ED, providing detailed information on their botanical characteristics, metabolic pathways, recommended dosages, phytochemical properties, side effects, origins, and traditional uses. It also reviews recent studies on medicinal herbs that boost sexual desire and treat urological conditions. By compiling reliable findings from the past decade, the study aims to serve as a comprehensive resource for individuals dealing with sexual health issues. Through careful evaluation of each herb, it offers insights into their effectiveness and limitations, emphasizing the potential of natural treatments as complementary alternatives to conventional therapies for male infertility and related conditions.

全球有 8-12% 的夫妇患有不育症,其中约 40% 的病例与男性因素有关。常见的男性不育问题包括勃起功能障碍(ED)和精子数量或质量低下,这两种情况占 90% 以上。这些问题通常是由解剖学、荷尔蒙或遗传异常造成的。本综述重点介绍常用于治疗 ED 的天然壮阳草药,详细介绍其植物特性、代谢途径、推荐剂量、植物化学特性、副作用、起源和传统用途。该书还回顾了有关提高性欲和治疗泌尿系统疾病的药草的最新研究。通过汇编过去十年的可靠研究结果,该研究旨在为个人处理性健康问题提供全面的资源。通过对每种草药的仔细评估,该书深入探讨了它们的有效性和局限性,强调了自然疗法作为常规疗法的补充替代品治疗男性不育症和相关疾病的潜力。
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引用次数: 0
Modifying effects of green space on the relationships between air pollution and ischemic cerebrovascular event recurrence in Tianjin, China. 绿地对中国天津市空气污染与缺血性脑血管事件复发之间关系的调节作用。
IF 2.2 4区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2024-10-01 Epub Date: 2024-02-15 DOI: 10.1080/09603123.2024.2314636
Zhiying Sun, Lu Chen, Zhonghui Liu, Lihong Feng, Yushan Cui, Xianwei Zhang, Yan Wu, Jingwei Zhang

This study aimed to explore how air pollution and green space influence ICE recurrence and whether they might interact with each other. A case-cross design was used in this study, which was carried out in Tianjin, China. A total of 8306 patients with recurrent ICE were collected from 2019 to 2020. The maximum effects of PM2.5, PM10, SO2, NO2, CO were 1.012 (95%CI: 1.004, 1.019), 1.010 (95%CI: 1.004, 1.016), 1.035 (95%CI: 0.982, 1.091), 1.067 (95%CI: 1.043, 1.091) and 1.012 (95%CI: 1.004, 1.021)  , respectively, and the risk was higher in males and in the 50-60 age group. In the stratification of greening, it was found that air pollution except O3 had the highest risk of ICE recurrence for those with lower green space. Our study found that air pollution (except O3) can increase the risk of ICE recurrence, and this risk can be reduced by increasing green space.

本研究旨在探讨空气污染和绿地如何影响 ICE 复发,以及二者是否会相互影响。本研究采用病例交叉设计,在中国天津进行。从2019年到2020年,共收集了8306名复发性ICE患者。PM2.5、PM10、SO2、NO2、CO的最大效应分别为1.012(95%CI:1.004,1.019)、1.010(95%CI:1.004,1.016)、1.035(95%CI:0.982,1.091)、1.男性和 50-60 岁年龄组的风险更高。在绿化分层中发现,除 O3 外,空气污染对绿化面积较小的人群来说,ICE 复发风险最高。我们的研究发现,空气污染(O3 除外)会增加 ICE 复发风险,而增加绿化面积可降低这一风险。
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引用次数: 0
Release and health outcomes of exposure to chalk particles in classrooms: a systematic literature review. 教室中粉笔颗粒的释放和健康影响:系统文献综述。
IF 2.2 4区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2024-10-01 Epub Date: 2024-02-04 DOI: 10.1080/09603123.2024.2311228
Setlamorago Jackson Mbazima, Raeesa Moolla, Jitcy Saji Joseph

This systematic review explores the release and health outcomes of exposure to chalk particles in classrooms. A literature search was conducted on Scopus, Google Scholar, and the Web of Science. Chalk particles contribute significantly to poor indoor air quality in classrooms. Higher concentrations of PM2.5 chalk particles were found in the front row (14.25 µg/m3) and near the chalkboard (19.07 µg/m3). Inhalation and dermal are significant exposure routes; hence, teachers and learners are at risk of developing respiratory and skin disorders. Inhalation of chalk particles correlates with reduced lung function in teachers and learners. The release and size of chalk particles depend on the activities, type of chalk sticks, and texture of the chalkboards. Wiping the chalkboard releases more chalk particles of smaller size (3.85-9.3 µm) than writing (10.57-92.91 µm). A shift from chalk sticks and chalkboards in classrooms is necessary to mitigate the associated health risks.

本系统综述探讨了教室中粉笔颗粒的释放和健康影响。我们在 Scopus、Google Scholar 和 Web of Science 上进行了文献检索。粉笔颗粒是造成教室室内空气质量差的重要原因。前排(14.25 微克/立方米)和黑板附近(19.07 微克/立方米)的粉笔颗粒 PM2.5 浓度较高。吸入和皮肤接触是重要的接触途径;因此,教师和学生都有患呼吸道疾病和皮肤疾病的风险。吸入粉笔微粒会导致教师和学生肺功能下降。粉笔颗粒的释放量和大小取决于活动、粉笔棒的类型和黑板的质地。擦黑板释放的粉笔颗粒(3.85-9.3 微米)比写字释放的粉笔颗粒(10.57-92.91 微米)要小。为了减少相关的健康风险,有必要改变教室中的粉笔棒和黑板。
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引用次数: 0
The contribution of decentralized water systems on water quality in Maniema province, DRC. 分散式供水系统对刚果民主共和国马涅马省水质的影响。
IF 2.2 4区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2024-10-01 Epub Date: 2024-02-08 DOI: 10.1080/09603123.2024.2312545
Renata Campos Nogueira, Marc-Antoine Menneguerre, Mami Daba Fam Thior, Timothée Miala, Antoine Mesu, Fabian Prod'homme

Decentralized water systems (DWS) distribute water in remote African areas. Throughout an intervention in Maniema, Congo, the influence of a DWS performing chlorination in the community's water quality was measured. Additionally, a socio-economic and WASH practices survey was conducted in the communities. Free residual chlorine (FRC) and microbiological contamination were measured; at the borehole, treatment site, distribution points, and households's water containers. In Big Five, water was collected from unimproved sources before DWS construction. Despite that, only 16,6% of households used efficient water treatment methods, resulting in 73% of water stored unsafe for consumption. After construction, household water quality drastically improved, regardless of FRC fluctuations; 93% of samples were classified as low health risk (safe). The renovation guaranteed continuous supply through electro-chlorinators in RVA, where chlorination was intermittent. Water from DWS with adequate chlorine levels prevented microbiological contamination in households for 12 hours. Although economically attractive, the system's sustainability will require future evaluation.

分散式供水系统(DWS)为非洲偏远地区供水。在刚果马涅马开展的一项干预活动中,我们测量了进行氯化处理的分散式供水系统对社区水质的影响。此外,还在社区开展了社会经济和讲卫生运动调查。测量了井眼、处理点、配水点和住户水容器中的游离余氯(FRC)和微生物污染情况。在大五区,在建造供水系统之前,人们从未经改善的水源取水。尽管如此,只有 16.6% 的家庭采用了有效的水处理方法,导致 73% 的储水不能安全饮用。供水系统建成后,家庭水质大幅改善,不受水质监测中心波动的影响;93% 的水样被归类为健康风险低(安全)。翻新工程保证了在 RVA 地区通过电解氯器持续供水,而在 RVA 地区,加氯是间歇性的。含氯量充足的 DWS 供水可在 12 小时内防止住户受到微生物污染。尽管该系统在经济上很有吸引力,但其可持续性还需要今后进行评估。
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引用次数: 0
Health benefits to vulnerable populations by meeting particle-level guidelines inside schools with different ventilation conditions. 在通风条件不同的学校内达到微粒含量标准,为弱势群体带来健康益处。
IF 2.2 4区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2024-10-01 Epub Date: 2024-02-15 DOI: 10.1080/09603123.2024.2305223
Shubham Rathi, Anubha Goel, Supreme Jain, Rushyendranath Sreeramoju

We conducted simultaneous real-time measurements for particles on the premises of four schools, two of which were naturally ventilated (NV) and two mechanically ventilated (MV) in Kanpur, India. Health to school children from reduced particle levels inside classrooms simulated to the lowest acceptable levels (ISHRAE Class C: PM10 ≤ 100 µg/m3 & PM2.5 ≤ 25 µg/m3) using air filters were examined. Lung deposition of particles was used as a proxy for health impacts and calculated using the MPPD model. The particle levels in all classrooms were above the baseline, with NV classrooms having higher particle masses than MV classrooms: 72.16% for PM1, 74.66% for PM2.5, and 85.17% for PM10. Our calculation reveals a whooping reduction in particles deposited in the lungs (1512% for PM10 and 1485% for PM2.5) in the case of the NV classrooms. Results highlight unhealthy air inside classrooms and suggest urgent interventions, such as simple filtration techniques, to achieve acceptable levels of particles inside schools.

我们在印度坎普尔的四所学校的校舍内同时进行了颗粒物实时测量,其中两所为自然通风(NV)学校,两所为机械通风(MV)学校。通过使用空气过滤器将教室内的颗粒物水平模拟到可接受的最低水平(ISHRAE C 级:PM10 ≤ 100 µg/m3 和 PM2.5 ≤ 25 µg/m3),对学童的健康状况进行了检测。颗粒物的肺沉积被用作健康影响的替代物,并使用 MPPD 模型进行计算。所有教室的颗粒物水平都高于基线,其中 NV 教室的颗粒物质量高于 MV 教室:PM1 为 72.16%,PM2.5 为 74.66%,PM10 为 85.17%。我们的计算显示,在 NV 教室,沉积在肺部的颗粒物大幅减少(PM10 减少了 1512%,PM2.5 减少了 1485%)。结果凸显了教室内不健康的空气,并建议采取紧急干预措施,如简单的过滤技术,以达到学校内可接受的颗粒物水平。
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引用次数: 0
Impact of air pollution from different sources on sperm DNA methylation. 不同来源的空气污染对精子 DNA 甲基化的影响
IF 2.2 4区 医学 Q3 ENVIRONMENTAL SCIENCES Pub Date : 2024-10-01 Epub Date: 2024-01-28 DOI: 10.1080/09603123.2024.2310152
Miluse Vozdova, Svatava Kubickova, Vera Kopecka, Alfredo Pauciullo, Jiri Rubes

Environmental exposure is associated with increased incidence of respiratory and cardiovascular diseases and reduced fertility. Exposure to air pollution can influence gene expression through epigenetic mechanisms. In this study, we analysed gene-specific CpG methylation in spermatozoa of city policemen occupationally exposed to air pollution in two Czech cities differing by sources and composition of the air pollution. In Prague, the pollution is mainly formed by NO2 from heavy traffic. Ostrava is a hotspot of industrial air pollution with high concentrations of particular matter (PM) and benzo[a]pyrene (B[a]P). We performed genome-wide methylation sequencing using the SureSelectXT Human Methyl-Seq system (Agilent Technologies) and next-generation sequencing to reveal differentially methylated CpG sites and regions. We identified differential methylation in the region chr5:662169 - 663376 annotated to genes CEP72 and TPPP. The region was then analysed in sperm DNA from 117 policemen using targeted methylation sequencing, which proved its hypermethylation in sperm of Ostrava policemen.

暴露于环境中与呼吸道和心血管疾病发病率的增加以及生育率的降低有关。暴露于空气污染可通过表观遗传机制影响基因表达。在这项研究中,我们分析了在捷克两个空气污染来源和成分不同的城市中,职业暴露于空气污染的城市警察精子中特异基因的 CpG 甲基化。在布拉格,污染主要由交通繁忙造成的二氧化氮形成。俄斯特拉发是工业空气污染的热点地区,特殊物质(PM)和苯并[a]芘(B[a]P)浓度较高。我们使用 SureSelectXT Human Methyl-Seq 系统(安捷伦科技公司)和新一代测序技术进行了全基因组甲基化测序,以揭示不同的甲基化 CpG 位点和区域。我们在注释为基因 CEP72 和 TPPP 的 chr5:662169 - 663376 区域发现了不同的甲基化。随后,我们使用靶向甲基化测序技术对 117 名警察的精子 DNA 中的该区域进行了分析,结果证明在俄斯特拉发警察的精子中该区域存在高甲基化。
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引用次数: 0
期刊
International Journal of Environmental Health Research
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