Pub Date : 2024-08-06DOI: 10.1080/09603123.2024.2386113
Vega Burgueño Mj, Torres Montoya Eh, Zazueta-Moreno Jm, Barron-Cabrera Em, Osuna-Martínez U, Urías-García Ej, Salinas-Garza Td, Ochoa-Acosta DA, Vergara-Jiménez Mj
Sucrose intake is a potential risk factor for non-alcoholic fatty liver disease (NAFLD). Individual characteristics such as sex, play arole in the biological variation of the disease, potentially related to genetic regulation. This research evaluated sex differences in biochemical, histopathological, and gene expression responses associated with NAFLD in C57bl/6N mice on a high sucrose diet. Female and male mice were assigned to control or high sucrose diets (50% sucrose solution) for 20 weeks. After sacrifice, blood and hepatic tissue were collected for analysis. Female mice revealed moderate-to-high NAFLD, whereas male mice showed mild-to-moderate NAFLD. Sex-specific variations were observed in Cd36 gene expression, an upregulation in females compared with the male group, and Adipor1 gene expression showed significant downregulation in the female group in response to high sucrose diet compared with the control group. These findings highlight the importance of considering gender disparities in the treatment and management of NAFLD.
{"title":"Sex-specific differences in NAFLD development: effect of a high-sucrose diet on biochemical, histological, and genetic markers in C57bl/6N mice.","authors":"Vega Burgueño Mj, Torres Montoya Eh, Zazueta-Moreno Jm, Barron-Cabrera Em, Osuna-Martínez U, Urías-García Ej, Salinas-Garza Td, Ochoa-Acosta DA, Vergara-Jiménez Mj","doi":"10.1080/09603123.2024.2386113","DOIUrl":"https://doi.org/10.1080/09603123.2024.2386113","url":null,"abstract":"<p><p>Sucrose intake is a potential risk factor for non-alcoholic fatty liver disease (NAFLD). Individual characteristics such as sex, play arole in the biological variation of the disease, potentially related to genetic regulation. This research evaluated sex differences in biochemical, histopathological, and gene expression responses associated with NAFLD in C57bl/6N mice on a high sucrose diet. Female and male mice were assigned to control or high sucrose diets (50% sucrose solution) for 20 weeks. After sacrifice, blood and hepatic tissue were collected for analysis. Female mice revealed moderate-to-high NAFLD, whereas male mice showed mild-to-moderate NAFLD. Sex-specific variations were observed in <i>Cd36</i> gene expression, an upregulation in females compared with the male group, and <i>Adipor1</i> gene expression showed significant downregulation in the female group in response to high sucrose diet compared with the control group. These findings highlight the importance of considering gender disparities in the treatment and management of NAFLD.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141897401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-04DOI: 10.1080/09603123.2024.2387153
Mohammad Ali Zazouli, Atefeh Zahedi, Susana Rodriguez, Yalda Hashempour
The Microbial Desalination Cell (MDC) stands out as an innovative and a sustainable technology for both renewable energy generation and water treatment. The choice of electron acceptor significantly influences the efficiency of electricity flow. This study focuses on exploring the MDC performance under different conditions, including variations in cathode electron acceptors, initial pH levels, and hydraulic retention time (HRT). The investigation assesses simultaneous reduction of TDS and power generation from Caspian Sea water, a prominent saline water source in northern Iran, in both open-circuit (OC) and closed-circuit (CC) modes. The findings reveal that sodium hypochlorite, potassium permanganate, and potassium bromate as catholyte achieved TDS reduction rates of 84%, 77%, and 72%, respectively, under CC conditions at pH 5. Furthermore, it was observed that increasing HRT and pH levels lead to a decrease in desalination efficiency and power generation. Notably, the study highlights that the maximum power density was attained using permanganate, hypochlorite, and bromate as catholyte in both OC and CC configurations. By showcasing the adaptability of MDC performance with different cathode electron acceptors under varying conditions, this research offers valuable insights for optimizing MDC efficiency when treating real saline water sources.
{"title":"Effect of electron acceptors on electricity production and desalination of caspian sea water using microbial desalination cells.","authors":"Mohammad Ali Zazouli, Atefeh Zahedi, Susana Rodriguez, Yalda Hashempour","doi":"10.1080/09603123.2024.2387153","DOIUrl":"https://doi.org/10.1080/09603123.2024.2387153","url":null,"abstract":"<p><p>The Microbial Desalination Cell (MDC) stands out as an innovative and a sustainable technology for both renewable energy generation and water treatment. The choice of electron acceptor significantly influences the efficiency of electricity flow. This study focuses on exploring the MDC performance under different conditions, including variations in cathode electron acceptors, initial pH levels, and hydraulic retention time (HRT). The investigation assesses simultaneous reduction of TDS and power generation from Caspian Sea water, a prominent saline water source in northern Iran, in both open-circuit (OC) and closed-circuit (CC) modes. The findings reveal that sodium hypochlorite, potassium permanganate, and potassium bromate as catholyte achieved TDS reduction rates of 84%, 77%, and 72%, respectively, under CC conditions at pH 5. Furthermore, it was observed that increasing HRT and pH levels lead to a decrease in desalination efficiency and power generation. Notably, the study highlights that the maximum power density was attained using permanganate, hypochlorite, and bromate as catholyte in both OC and CC configurations. By showcasing the adaptability of MDC performance with different cathode electron acceptors under varying conditions, this research offers valuable insights for optimizing MDC efficiency when treating real saline water sources.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141889155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01Epub Date: 2023-11-06DOI: 10.1080/09603123.2023.2277338
Ivan Nelinho Pérez-Maldonado, Carlos Gabriel De la Trinidad-Chacón, Amairani Lizbeth Perez-Lopez, Anette Aylin Perez-Lopez
Emerging scientific studies have supported the hypothesis that exposure to environmental chemicals increases the incidence of diverse human metabolic disorders. Therefore, this study aimed to evaluate the association between fluoride exposure and metabolic syndrome (MetS) prevalence in people from the Central Region of Mexico. This research included 575 adult individuals. Urinary fluoride concentrations were determined using a potentiometric method. Anthropometric measurements and blood pressure were also acquired. Serum fasting glucose and lipid levels were quantified. For the MetS screening, we used the International Diabetes Federation (IDF) and National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria. The mean urinary fluoride levels were 3.50 ± 2.50 mg/L. The prevalence of MetS was approximately 27 and 25% according to NCEP ATP III and IDF criteria, respectively. A multivariate logistic regression analysis showed significant associations (p < 0.05) between urinary fluoride concentrations and MetS occurrence using NCEP ATP III criteria (OR = 1.60; 95% CI 1.05-2.10) and IDF criteria (OR = 1.35; 95% CI 0.95-1.45). These findings emphasize the need to discover the underlying mechanisms that fluoride exposure has on MetS pathogenesis.
新兴的科学研究支持了这样一种假设,即暴露于环境化学物质会增加多种人类代谢紊乱的发生率。因此,本研究旨在评估墨西哥中部地区人群中氟暴露与代谢综合征(MetS)患病率之间的关系。这项研究包括575名成年个体。尿氟浓度采用电位法测定。还获得了人体测量和血压。测定血清空腹血糖和血脂水平。对于MetS筛查,我们使用了国际糖尿病联合会(IDF)和国家胆固醇教育计划成人治疗小组III(NCEP ATP III)标准。平均尿氟水平为3.50 ± 2.50 mg/L。根据NCEP ATP III和IDF标准,MetS的患病率分别约为27%和25%。多变量逻辑回归分析显示出显著的相关性(p
{"title":"Association between urinary fluoride concentrations and the prevalence of metabolic syndrome in adult individuals from the Central Region of Mexico.","authors":"Ivan Nelinho Pérez-Maldonado, Carlos Gabriel De la Trinidad-Chacón, Amairani Lizbeth Perez-Lopez, Anette Aylin Perez-Lopez","doi":"10.1080/09603123.2023.2277338","DOIUrl":"10.1080/09603123.2023.2277338","url":null,"abstract":"<p><p>Emerging scientific studies have supported the hypothesis that exposure to environmental chemicals increases the incidence of diverse human metabolic disorders. Therefore, this study aimed to evaluate the association between fluoride exposure and metabolic syndrome (MetS) prevalence in people from the Central Region of Mexico. This research included 575 adult individuals. Urinary fluoride concentrations were determined using a potentiometric method. Anthropometric measurements and blood pressure were also acquired. Serum fasting glucose and lipid levels were quantified. For the MetS screening, we used the International Diabetes Federation (IDF) and National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria. The mean urinary fluoride levels were 3.50 ± 2.50 mg/L. The prevalence of MetS was approximately 27 and 25% according to NCEP ATP III and IDF criteria, respectively. A multivariate logistic regression analysis showed significant associations (<i>p</i> < 0.05) between urinary fluoride concentrations and MetS occurrence using NCEP ATP III criteria (OR = 1.60; 95% CI 1.05-2.10) and IDF criteria (OR = 1.35; 95% CI 0.95-1.45). These findings emphasize the need to discover the underlying mechanisms that fluoride exposure has on MetS pathogenesis.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71481291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01Epub Date: 2023-11-17DOI: 10.1080/09603123.2023.2283048
Yi Zhang, Pai Zheng, Jiaqi Shi, Ying Ma, Zhangjian Chen, Tiancheng Wang, Guang Jia
The association between short-term ambient air pollution (AAP) exposure and blood lipids is inconsistent across populations. This study aimed to investigate the modifying effects of fasting blood glucose (FBG) levels on the associations between short-term AAP exposure and blood lipids in 110,637 male participants from Beijing, China. The results showed that FBG modified the association between short-term AAP exposure and blood lipids, especially low-density lipoprotein cholesterol (LDL-C). In the hyperglycemia group, a 10-μg/m3 increase in particles with diameters ≤ 2.5 μm (PM2.5), particles with diameters ≤ 10 μm (PM10), sulfur dioxide (SO2), nitrogen dioxide (NO2), or a 1-mg/m3 increase in carbon monoxide (CO) was associated with a 0.454%, 0.305%, 1.507%, 0.872%, or 3.961% increase in LDL-C, respectively. In the nonhyperglycemic group, short-term increases in air pollutants were even associated with small decreases in LDL-C. The findings demonstrate that lipids in hyperglycemic individuals are more vulnerable to short-term AAP exposure than those in normal populations.
{"title":"The modification effect of fasting blood glucose level on the associations between short-term ambient air pollution and blood lipids.","authors":"Yi Zhang, Pai Zheng, Jiaqi Shi, Ying Ma, Zhangjian Chen, Tiancheng Wang, Guang Jia","doi":"10.1080/09603123.2023.2283048","DOIUrl":"10.1080/09603123.2023.2283048","url":null,"abstract":"<p><p>The association between short-term ambient air pollution (AAP) exposure and blood lipids is inconsistent across populations. This study aimed to investigate the modifying effects of fasting blood glucose (FBG) levels on the associations between short-term AAP exposure and blood lipids in 110,637 male participants from Beijing, China. The results showed that FBG modified the association between short-term AAP exposure and blood lipids, especially low-density lipoprotein cholesterol (LDL-C). In the hyperglycemia group, a 10-μg/m<sup>3</sup> increase in particles with diameters ≤ 2.5 μm (PM<sub>2.5</sub>), particles with diameters ≤ 10 μm (PM<sub>10</sub>), sulfur dioxide (SO<sub>2</sub>), nitrogen dioxide (NO<sub>2</sub>), or a 1-mg/m<sup>3</sup> increase in carbon monoxide (CO) was associated with a 0.454%, 0.305%, 1.507%, 0.872%, or 3.961% increase in LDL-C, respectively. In the nonhyperglycemic group, short-term increases in air pollutants were even associated with small decreases in LDL-C. The findings demonstrate that lipids in hyperglycemic individuals are more vulnerable to short-term AAP exposure than those in normal populations.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136397362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The present study was conducted to investigate the heavy metal pollution status of the agricultural soils in Ramhormoz Plain, Khuzestan province, Iran. A total of 54 samples from the depths (0-20 cm) of the soil were collected from the selected areas in (March) 2021. According to the obtained results, the concentrations of As, Cd, Cr, Cu, Hg, Mn, Ni, Pb, Zn, Al in soil samples were 1.3, 0.68, 60, 10.6, 0.01, 218, 23, 3.65, 14 and 0.58 mg/kg, respectively, in which As showed significant soil contamination and Cu, Hg, Mn, Ni, Pb, Zn and Al moderate contamination according to the calculation of contamination factor (CF). PCA analysis revealed that both anthropogenic and natural sources of pollution like agricultural and transport activities contributed to the enrichment of study area. Investigation of ecological risk indicated that Ramhormoz Plain was categorized as a high risk area.
{"title":"Determination of geochemical baselines and evaluation of potentially toxic elements in agricultural soils of Ramhormoz Plain, Iran.","authors":"Sudabeh Porfadakari, Sahand Jorfi, Maryam Ravanbakhash, Nastaran Talepour, Razieh Karimian","doi":"10.1080/09603123.2023.2283060","DOIUrl":"10.1080/09603123.2023.2283060","url":null,"abstract":"<p><p>The present study was conducted to investigate the heavy metal pollution status of the agricultural soils in Ramhormoz Plain, Khuzestan province, Iran. A total of 54 samples from the depths (0-20 cm) of the soil were collected from the selected areas in (March) 2021. According to the obtained results, the concentrations of As, Cd, Cr, Cu, Hg, Mn, Ni, Pb, Zn, Al in soil samples were 1.3, 0.68, 60, 10.6, 0.01, 218, 23, 3.65, 14 and 0.58 mg/kg, respectively, in which As showed significant soil contamination and Cu, Hg, Mn, Ni, Pb, Zn and Al moderate contamination according to the calculation of contamination factor (CF). PCA analysis revealed that both anthropogenic and natural sources of pollution like agricultural and transport activities contributed to the enrichment of study area. Investigation of ecological risk indicated that Ramhormoz Plain was categorized as a high risk area.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138440686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01Epub Date: 2024-01-03DOI: 10.1080/09603123.2023.2293063
Nafiseh Nasirzadeh, Mohammad Reza Monazam Esmaielpour, Farideh Golbabaei
{"title":"The role of submicron zinc oxide particle size in improving UV protection by textiles.","authors":"Nafiseh Nasirzadeh, Mohammad Reza Monazam Esmaielpour, Farideh Golbabaei","doi":"10.1080/09603123.2023.2293063","DOIUrl":"10.1080/09603123.2023.2293063","url":null,"abstract":"","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139080530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01Epub Date: 2023-11-15DOI: 10.1080/09603123.2023.2280661
Abiola Olawale Ilori, Naven Chetty
According to reports, exposure to high concentrations of naturally occurring radioactive substances like Uranium-238, Thorium-232, and Potassium-40 poses serious health concerns. This review study aims to report the concentrations of radionuclides in various South African soil and their equivalent risk assessments, which have been sparingly reported. For South Africa, most radionuclide concentrations above the permissible limits of 33, 45, and 420 Bq.kg-1 for 238U, 232Th, and 40K, respectively, have been found in some soil samples taken near industrialization activities, including mining and oil exploration and production. Thus, the amount of radionuclides is a good indicator of the kind of soil, the local geology, and the mineral make-up of the parent rocks. The increases in radiation exposure to people and the environment have been reported to cause various radiological health hazards. Thus, this review study can be used as a data source to track probable radioactive contamination from soils found in South Africa.
{"title":"A review of the occurrence of naturally occurring radioactive materials and radiological risk assessment in South African soils.","authors":"Abiola Olawale Ilori, Naven Chetty","doi":"10.1080/09603123.2023.2280661","DOIUrl":"10.1080/09603123.2023.2280661","url":null,"abstract":"<p><p>According to reports, exposure to high concentrations of naturally occurring radioactive substances like Uranium-238, Thorium-232, and Potassium-40 poses serious health concerns. This review study aims to report the concentrations of radionuclides in various South African soil and their equivalent risk assessments, which have been sparingly reported. For South Africa, most radionuclide concentrations above the permissible limits of 33, 45, and 420 Bq.kg<sup>-1</sup> for <sup>238</sup>U, <sup>232</sup>Th, and <sup>40</sup>K, respectively, have been found in some soil samples taken near industrialization activities, including mining and oil exploration and production. Thus, the amount of radionuclides is a good indicator of the kind of soil, the local geology, and the mineral make-up of the parent rocks. The increases in radiation exposure to people and the environment have been reported to cause various radiological health hazards. Thus, this review study can be used as a data source to track probable radioactive contamination from soils found in South Africa.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134648877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01Epub Date: 2023-11-26DOI: 10.1080/09603123.2023.2286007
Anan S Jarab, Walid Al-Qerem, Haya Y Alajlouni, Karem H Alzoubi, Shrouq Abu Heshmeh, Tareq L Mukattash, Abdallah Y Naser, Yazid N Al Hamarneh
Drug-Food Interaction (DFI) can potentially lead to treatment ineffectiveness and adverse health outcomes. This study investigated knowledge and attitude towards DFI and the associated factors. A validated questionnaire was distributed to 2040 participants across Jordan. The participants had moderate knowledge and attitudes regarding DFIs. Regression results revealed that male gender, lower education level, not working in the healthcare sector, and utilizing non-scientific sources of information about DFIs were associated with lower knowledge about DFI. Furthermore, male gender, being unmarried, having a low or moderate education level, not working in the healthcare sector, not having a family member with chronic disease, and having low knowledge of DFI were significantly associated with negative attitudes towards DFIs. Future health education programs should emphasize using reliable scientific sources to enhance awareness about DFIs'. Additionally, healthcare professionals should counsel patients on avoiding DFIs and provide guidance accordingly.
{"title":"Public knowledge and attitude towards drug-food interactions: implications for improved public health safety.","authors":"Anan S Jarab, Walid Al-Qerem, Haya Y Alajlouni, Karem H Alzoubi, Shrouq Abu Heshmeh, Tareq L Mukattash, Abdallah Y Naser, Yazid N Al Hamarneh","doi":"10.1080/09603123.2023.2286007","DOIUrl":"10.1080/09603123.2023.2286007","url":null,"abstract":"<p><p>Drug-Food Interaction (DFI) can potentially lead to treatment ineffectiveness and adverse health outcomes. This study investigated knowledge and attitude towards DFI and the associated factors. A validated questionnaire was distributed to 2040 participants across Jordan. The participants had moderate knowledge and attitudes regarding DFIs. Regression results revealed that male gender, lower education level, not working in the healthcare sector, and utilizing non-scientific sources of information about DFIs were associated with lower knowledge about DFI. Furthermore, male gender, being unmarried, having a low or moderate education level, not working in the healthcare sector, not having a family member with chronic disease, and having low knowledge of DFI were significantly associated with negative attitudes towards DFIs. Future health education programs should emphasize using reliable scientific sources to enhance awareness about DFIs'. Additionally, healthcare professionals should counsel patients on avoiding DFIs and provide guidance accordingly.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138440687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01Epub Date: 2023-12-01DOI: 10.1080/09603123.2023.2289047
Marie-Médiatrice Kikongo Ntabugi, Bahati J Manegabe, John B Dewar, Christian Sekomo Birame
Infection with multidrug resistant bacteria is a significant public health concern. Bacteria culture of water samples (n=120) collected in San Cristobal River, Philippines, showed that half (n=60) were positive for Salmonella spp. Screening of all isolates (n=179) for susceptibility to antibiotics showed that most (76.4%; n=113) were positive for class 1 integrons, of which one isolate was also positive for the class 2 integron. The presence of class 1 integrons was associated with resistance to antibiotics (p<0.05). Sequencing of class 1 integron variable regions (VRs) differeciated 11 gene cassettes: dfrA1 or dfrA17; aadA1 or aadA2; blaCTX-M-2 or bla-OXA-1; SmdAB; CmlA1 and aaC 3-Id. However, sequencing of class 2 integron VR differenciated estX, sat2, and aadA1. These results provide insights into evolutionary changes within bacterial multidrug resistant cassettes, more accurately to estimate heath risk associated with the river water. .
{"title":"Class 1 and 2 integrons and antibiotic resistance profile in <i>Salmonella</i> spp. from San Cristobal River, Laguna, Philippines.","authors":"Marie-Médiatrice Kikongo Ntabugi, Bahati J Manegabe, John B Dewar, Christian Sekomo Birame","doi":"10.1080/09603123.2023.2289047","DOIUrl":"10.1080/09603123.2023.2289047","url":null,"abstract":"<p><p>Infection with multidrug resistant bacteria is a significant public health concern. Bacteria culture of water samples (n=120) collected in San Cristobal River, Philippines, showed that half (n=60) were positive for Salmonella spp. Screening of all isolates (n=179) for susceptibility to antibiotics showed that most (76.4%; n=113) were positive for class 1 integrons, of which one isolate was also positive for the class 2 integron. The presence of class 1 integrons was associated with resistance to antibiotics (p<0.05). Sequencing of class 1 integron variable regions (VRs) differeciated 11 gene cassettes: dfrA1 or dfrA17; aadA1 or aadA2; blaCTX-M-2 or bla-OXA-1; SmdAB; CmlA1 and aaC 3-Id. However, sequencing of class 2 integron VR differenciated estX, sat2, and aadA1. These results provide insights into evolutionary changes within bacterial multidrug resistant cassettes, more accurately to estimate heath risk associated with the river water. .</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138459808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study delved into the incorporation of wild nettle (Urtica dioica L.) leaves powder with virgin olive oil, exploring its potential to enhance nutritional value and health benefits. The antioxidant, antibacterial, and mineral-enrichment attributes of the resultant nettle-infused olive oil were investigated. Phenolic composition analysis revealed that an optimal maceration time of 30-40 minutes leads to maximal phenolic and flavonoid contents (57.66 mg GAE/100 g and 67.18 mg QE/100 g, respectively). The infused oil demonstrated superior radical scavenging activity (DPPH and ABTS assays) compared to virgin olive oil. Notably, nettle infusion significantly elevates zinc (10.12 mg/kg) and iron (13.85 mg/kg) contents. Antibacterial assays exhibited enhanced inhibition diameters and lower MIC and MBC values for nettle-infused oil against various bacterial strains. The study's findings underscore the potential of nettle infusion to enhance the nutritional and functional attributes of olive oil, holding promise for novel culinary and health applications.
{"title":"Exploring the synergistic potential of wild nettle and olive oil: bioactive compounds, antioxidant capacity, and antibacterial properties.","authors":"Hedia Manai-Djebali, Walid Yeddes, Majdi Hammami, Salma Nait-Mohamed, Emna Habachi, Kamel Msaada, Nabil Ben Youssef","doi":"10.1080/09603123.2023.2287589","DOIUrl":"10.1080/09603123.2023.2287589","url":null,"abstract":"<p><p>This study delved into the incorporation of wild nettle (<i>Urtica dioica</i> L.) leaves powder with virgin olive oil, exploring its potential to enhance nutritional value and health benefits. The antioxidant, antibacterial, and mineral-enrichment attributes of the resultant nettle-infused olive oil were investigated. Phenolic composition analysis revealed that an optimal maceration time of 30-40 minutes leads to maximal phenolic and flavonoid contents (57.66 mg GAE/100 g and 67.18 mg QE/100 g, respectively). The infused oil demonstrated superior radical scavenging activity (DPPH and ABTS assays) compared to virgin olive oil. Notably, nettle infusion significantly elevates zinc (10.12 mg/kg) and iron (13.85 mg/kg) contents. Antibacterial assays exhibited enhanced inhibition diameters and lower MIC and MBC values for nettle-infused oil against various bacterial strains. The study's findings underscore the potential of nettle infusion to enhance the nutritional and functional attributes of olive oil, holding promise for novel culinary and health applications.</p>","PeriodicalId":14039,"journal":{"name":"International Journal of Environmental Health Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138477547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}