Literature supports the education levels of an individual is important for language performance. Cognitive reserve within individuals can be explained on the basis of years of education, occupational achievements, reading habits and lifestyle of an individual. This retrospective study is a preliminary attempt to determine relationship between premorbid educational level and initial aphasia severity. For this purpose, thirty-two Malayalam speaking individuals with aphasia with a maximum post stroke period of three months having three levels of educational qualifications, below and above tenth grade and under graduates were selected. Detailed speech and language assessment were carried out using formal assessment tool. The severity of language impairment was determined by calculating Aphasia quotient. One way ANOVA was used to determine statistical significance. Although, subjects had similarities in pattern of Cerebrovascular accidents severity of aphasia varies. The subjects with lower Aphasia Quotient are present in all groups, illustrating that there is less corelation between the subjects' educational attainment and the severity of their communication problems. Key words: Aphasia, Formal education, Aphasia Quotient
{"title":"Effect of Formal Education on Initial Severity of Aphasia - A Retrospective Analysis","authors":"Rahul Kumminimana, Anuradha S, Hamza Mullath","doi":"10.52403/ijhsr.20240613","DOIUrl":"https://doi.org/10.52403/ijhsr.20240613","url":null,"abstract":"Literature supports the education levels of an individual is important for language performance. Cognitive reserve within individuals can be explained on the basis of years of education, occupational achievements, reading habits and lifestyle of an individual. This retrospective study is a preliminary attempt to determine relationship between premorbid educational level and initial aphasia severity. For this purpose, thirty-two Malayalam speaking individuals with aphasia with a maximum post stroke period of three months having three levels of educational qualifications, below and above tenth grade and under graduates were selected. Detailed speech and language assessment were carried out using formal assessment tool. The severity of language impairment was determined by calculating Aphasia quotient. One way ANOVA was used to determine statistical significance. Although, subjects had similarities in pattern of Cerebrovascular accidents severity of aphasia varies. The subjects with lower Aphasia Quotient are present in all groups, illustrating that there is less corelation between the subjects' educational attainment and the severity of their communication problems.\u0000\u0000Key words: Aphasia, Formal education, Aphasia Quotient","PeriodicalId":14119,"journal":{"name":"International Journal of Health Sciences and Research","volume":" 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141368599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dr. C. Sugumari, Dr. G. Manjula, Dr. A. Seetha, Dr. A. Selva Prabhu, M. Ranjith, G. Gayathri
Aim: To determine the incidence of Dengue in Madurai city during 2021 & 2022 by Dengue IgM ELISA and to analyse the epidemiological trend of Dengue infection including age, gender and seasonal variation. Methods: Serum samples from the suspected patients were screened using IgM antibody ELISA. Results: Maximum number of DENV cases occurred between October to March ranging from 43.3% in 2021 to 31.1% in 2022, with the peak in 2021 in February (19.7%) and in 2022 peak incidence was in January (18.1%). Dengue seropositivity was high in males than that of females. Though there is a slight difference, this is not statistically significant. Dengue positivity rate was the highest in Children less than 10 years and 11 – 20 years in 2021 and 11 – 20 & 21 – 30 years in 2022. In 2021 and 2022 more number of cases was found in Zone 4 followed by Zone 2. Zone 4 seems to be having more number of cases in both years. Conclusion: This study is another evidence which revealed that the incidence of dengue cases is spatially distributed in entire Madurai Corporation area and also the active circulation of DENV in several parts of the Tamil Nadu. The state health department needs to direct their efforts not only to control the spread but also on the future preparedness to prevent outbreaks. Key words: Dengue, IgM ELISA, Epidemiological and Madurai Corporation
{"title":"Epidemiological Scenario of Dengue Infection Over Two Years During 2021-2022, in Madurai Corporation","authors":"Dr. C. Sugumari, Dr. G. Manjula, Dr. A. Seetha, Dr. A. Selva Prabhu, M. Ranjith, G. Gayathri","doi":"10.52403/ijhsr.20240619","DOIUrl":"https://doi.org/10.52403/ijhsr.20240619","url":null,"abstract":"Aim: To determine the incidence of Dengue in Madurai city during 2021 & 2022 by Dengue IgM ELISA and to analyse the epidemiological trend of Dengue infection including age, gender and seasonal variation.\u0000Methods: Serum samples from the suspected patients were screened using IgM antibody ELISA.\u0000Results: Maximum number of DENV cases occurred between October to March ranging from 43.3% in 2021 to 31.1% in 2022, with the peak in 2021 in February (19.7%) and in 2022 peak incidence was in January (18.1%). Dengue seropositivity was high in males than that of females. Though there is a slight difference, this is not statistically significant. Dengue positivity rate was the highest in Children less than 10 years and 11 – 20 years in 2021 and 11 – 20 & 21 – 30 years in 2022. In 2021 and 2022 more number of cases was found in Zone 4 followed by Zone 2. Zone 4 seems to be having more number of cases in both years.\u0000Conclusion: This study is another evidence which revealed that the incidence of dengue cases is spatially distributed in entire Madurai Corporation area and also the active circulation of DENV in several parts of the Tamil Nadu. The state health department needs to direct their efforts not only to control the spread but also on the future preparedness to prevent outbreaks.\u0000\u0000Key words: Dengue, IgM ELISA, Epidemiological and Madurai Corporation","PeriodicalId":14119,"journal":{"name":"International Journal of Health Sciences and Research","volume":" 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141370804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Non ST elevated acute coronary syndrome (NSTE-ACS) is common and comprises of around one third of total patient of acute coronary syndrome (ACS). Evaluation and management is difficult due to complex pathophysiology involved. Traditionally echocardiography helps to assess these patients non-invasively before they are taken to cardiac catheterization laboratory. Speckle tracking echocardiography (STE) is an evolving modality by which more accurate assessment of left ventricular (LV) function can be done. STE also helps in identification of culprit artery responsible for the cardiac event. In our study we tried to correlate angiographic finding with global and regional strain echocardiography of LV in patients with NSTE-ACS. Total 50 patients were included in this cross- sectional study and we found that poor global longitudinal strain (GLS) of LV was associated with critical, multivessel coronary artery disease (MVCAD) with or without involvement of Left main coronary artery (LMCA) Key words: NSTE-ACS, LV, Regional strain, global strain, STE
{"title":"Evaluation of Global and Regional Strain and Angiographic Correlation in Patients with Non-ST Elevation Acute Coronary Syndrome (NSTE-ACS)","authors":"Sandipta Ray, Subir Sen, Sebabrata Jana","doi":"10.52403/ijhsr.20240610","DOIUrl":"https://doi.org/10.52403/ijhsr.20240610","url":null,"abstract":"Non ST elevated acute coronary syndrome (NSTE-ACS) is common and comprises of around one third of total patient of acute coronary syndrome (ACS). Evaluation and management is difficult due to complex pathophysiology involved.\u0000Traditionally echocardiography helps to assess these patients non-invasively before they are taken to cardiac catheterization laboratory.\u0000Speckle tracking echocardiography (STE) is an evolving modality by which more accurate assessment of left ventricular (LV) function can be done. STE also helps in identification of culprit artery responsible for the cardiac event.\u0000In our study we tried to correlate angiographic finding with global and regional strain echocardiography of LV in patients with NSTE-ACS.\u0000Total 50 patients were included in this cross- sectional study and we found that poor global longitudinal strain (GLS) of LV was associated with critical, multivessel coronary artery disease (MVCAD) with or without involvement of Left main coronary artery (LMCA)\u0000\u0000Key words: NSTE-ACS, LV, Regional strain, global strain, STE","PeriodicalId":14119,"journal":{"name":"International Journal of Health Sciences and Research","volume":" 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141368181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Various occupational hazards are seen in the workers working in different industries. In the industrial area, the workers might have effect on their health due to extended hours of working and exposure to various substances emitted from different industries in the environment. So, to assess lung function Peak Expiratory Flow Rate is measured. Materials and Method: A cross sectional study was carried on 120 male industrial workers between the age group of 21-50 years. The aim of the study was explained and informed consent was taken. Peak Expiratory Flow Rate was measured by using Wrights peak flow meter. The use of instrument was demonstrated to all participants. The data was analysed using descriptive statistics in Microsoft Excel 2021. Result: The highest of the three readings obtained was considered as peak flow rate, using statistical method mean was calculated. The mean of Peak Expiratory Flow Rate was 381.0 L/min. With years of exposure, the results show slight difference in peak flow rate. The industrial workers were using protective equipments while working. Conclusion: This study can be used to take earliest preventive measures in workers to avoid respiratory conditions. Monitoring of Peak Expiratory Flow Rate at regular intervals can be planned to detect respiratory pathophysiology in workers. Key words: industrial workers, Wrights peak flow meter, peak expiratory flow rate.
{"title":"Assessment of Peak Expiratory Flow Rate in Industrial Workers of MIDC, Lote","authors":"Naima Khot, S. Phadke","doi":"10.52403/ijhsr.20240608","DOIUrl":"https://doi.org/10.52403/ijhsr.20240608","url":null,"abstract":"Background: Various occupational hazards are seen in the workers working in different industries. In the industrial area, the workers might have effect on their health due to extended hours of working and exposure to various substances emitted from different industries in the environment. So, to assess lung function Peak Expiratory Flow Rate is measured.\u0000Materials and Method: A cross sectional study was carried on 120 male industrial workers between the age group of 21-50 years. The aim of the study was explained and informed consent was taken. Peak Expiratory Flow Rate was measured by using Wrights peak flow meter. The use of instrument was demonstrated to all participants. The data was analysed using descriptive statistics in Microsoft Excel 2021.\u0000Result: The highest of the three readings obtained was considered as peak flow rate, using statistical method mean was calculated. The mean of Peak Expiratory Flow Rate was 381.0 L/min. With years of exposure, the results show slight difference in peak flow rate. The industrial workers were using protective equipments while working.\u0000Conclusion: This study can be used to take earliest preventive measures in workers to avoid respiratory conditions. Monitoring of Peak Expiratory Flow Rate at regular intervals can be planned to detect respiratory pathophysiology in workers.\u0000\u0000Key words: industrial workers, Wrights peak flow meter, peak expiratory flow rate.","PeriodicalId":14119,"journal":{"name":"International Journal of Health Sciences and Research","volume":" 39","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141370145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karra Geetha, T. Chandana, R. Sakshi, C. S. Chandu, T. Ramarao
Pharmacogenomics, the study of how genetic variations influence drug response, has emerged as a cornerstone of personalized medicine, revolutionizing clinical practice across various medical specialties. This comprehensive review explores the applications, challenges, and prospects of pharmacogenomics in healthcare, with a particular focus on oncology. The integration of pharmacogenomic data into clinical decision-making processes enables healthcare providers to tailor drug therapy to individual patients based on their genetic makeup, thereby optimizing treatment outcomes while minimizing adverse effects. In oncology, pharmacogenomic testing plays a pivotal role in individualizing cancer therapy, predicting chemotherapy response, and selecting targeted therapies based on patients' genetic profiles. However, the widespread implementation of pharmacogenomics faces several challenges, including the need for robust evidence supporting its clinical utility, standardization of testing methodologies, and integration of genetic data into electronic health records. Despite these challenges, ongoing research efforts continue to advance our understanding of the genetic determinants of drug response, paving the way for personalized medicine to become an integral part of routine clinical practice. By addressing these challenges and leveraging technological advancements, pharmacogenomics holds the promise of enhancing patient care, improving treatment outcomes, and ultimately transforming the delivery of healthcare. Key words: Pharmacogenomics, personalized medicine, drug response, oncology, genetic variations, clinical practice
{"title":"Pharmacogenomics in Healthcare: Applications, Challenges, and Future Directions with a Focus on Oncology","authors":"Karra Geetha, T. Chandana, R. Sakshi, C. S. Chandu, T. Ramarao","doi":"10.52403/ijhsr.20240618","DOIUrl":"https://doi.org/10.52403/ijhsr.20240618","url":null,"abstract":"Pharmacogenomics, the study of how genetic variations influence drug response, has emerged as a cornerstone of personalized medicine, revolutionizing clinical practice across various medical specialties. This comprehensive review explores the applications, challenges, and prospects of pharmacogenomics in healthcare, with a particular focus on oncology. The integration of pharmacogenomic data into clinical decision-making processes enables healthcare providers to tailor drug therapy to individual patients based on their genetic makeup, thereby optimizing treatment outcomes while minimizing adverse effects. In oncology, pharmacogenomic testing plays a pivotal role in individualizing cancer therapy, predicting chemotherapy response, and selecting targeted therapies based on patients' genetic profiles.\u0000However, the widespread implementation of pharmacogenomics faces several challenges, including the need for robust evidence supporting its clinical utility, standardization of testing methodologies, and integration of genetic data into electronic health records. Despite these challenges, ongoing research efforts continue to advance our understanding of the genetic determinants of drug response, paving the way for personalized medicine to become an integral part of routine clinical practice. By addressing these challenges and leveraging technological advancements, pharmacogenomics holds the promise of enhancing patient care, improving treatment outcomes, and ultimately transforming the delivery of healthcare.\u0000\u0000Key words: Pharmacogenomics, personalized medicine, drug response, oncology, genetic variations, clinical practice","PeriodicalId":14119,"journal":{"name":"International Journal of Health Sciences and Research","volume":" 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141370075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Non-communicable diseases are among the leading cause of morbidity and mortality in India Objective: The present study aimed at identifying the prevalence of Diabetes mellitus, hypertension and their associated risk factors. Methods: Descriptive survey design was used and 145 adults were selected by using non-probability purposive sampling technique. Random blood sugar and blood pressure were measured. Risk factors such as Smoking, alcohol intake, unhealthy dietary habits, physical inactivity and BMI were assessed. Results: 16% of subject’s blood sugar was above normal. Blood pressure was high among 41% of subjects. 10%, 9% of subjects reported smoking, alcohol intake respectively. BMI was high among 43% of subjects. A significant portion of study subjects had unhealthy dietary habits and physical inactivity. 46.3% subjects had more than two risk factors. Conclusion: The current study reveals a high prevalence of DM, HTN and several risk factors among the study subjects, which calls for immediate action to curb this epidemic. Key words: Non communicable diseases (NCDs), Diabetes mellitus, Hypertension, Risk factors
{"title":"Estimates of Diabetes Mellitus and Hypertension and Associated Risk Factors","authors":"Jeyanthi Shanmugam K, C. P","doi":"10.52403/ijhsr.20240611","DOIUrl":"https://doi.org/10.52403/ijhsr.20240611","url":null,"abstract":"Background: Non-communicable diseases are among the leading cause of morbidity and mortality in India\u0000Objective: The present study aimed at identifying the prevalence of Diabetes mellitus, hypertension and their associated risk factors.\u0000Methods: Descriptive survey design was used and 145 adults were selected by using non-probability purposive sampling technique. Random blood sugar and blood pressure were measured. Risk factors such as Smoking, alcohol intake, unhealthy dietary habits, physical inactivity and BMI were assessed.\u0000Results: 16% of subject’s blood sugar was above normal. Blood pressure was high among 41% of subjects. 10%, 9% of subjects reported smoking, alcohol intake respectively. BMI was high among 43% of subjects. A significant portion of study subjects had unhealthy dietary habits and physical inactivity. 46.3% subjects had more than two risk factors.\u0000Conclusion: The current study reveals a high prevalence of DM, HTN and several risk factors among the study subjects, which calls for immediate action to curb this epidemic.\u0000\u0000Key words: Non communicable diseases (NCDs), Diabetes mellitus, Hypertension, Risk factors","PeriodicalId":14119,"journal":{"name":"International Journal of Health Sciences and Research","volume":" 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141368285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: To study the prevalence of De Quervain’s Tenosynovitis in cobblers. Objective: To assess De Quervain’s Tenosynovitis using the Finkelstein’s test in cobblers. Methodology: 350 subjects were selected according to the inclusion and exclusion criteria. A written informed consent was taken from the subjects, and were explained about the procedure. The Finkelstein test was performed in the dominant hand of the subject. A positive test indicated by a sharp shooting pain over the abductor pollicis longus and extensor pollicis brevis tendons at the wrist contributing to the painful entrapment of these two tendons. The data was collected and further evaluated statistically. Statistics & Results: Total 350 Cobblers were included in the study out of which 35% of total population assessed had De Quervain’s Tenosynovitis. When assessed within this positive result, 84% showed symptoms perceiving in right hand, and 16% in their left hand particularly based on the hand of dominance of the cobblers. Conclusions: The study concludes that the prevalence of De Quervain’s Tenosynovitis is fairly high in cobblers due to their self-limiting working pattern and requires ergonomic interventions and awareness about postural correction to prevent further musculoskeletal problems. Key words: De Quervain’s Tenosynovitis, Cobblers, Finkelstein Test, Work Related Musculoskeletal Dis-orders, Wrist Tendonitis.
{"title":"Prevalence of De Quervain’s Tenosynovitis in\u0000Cobblers","authors":"Zeel S. Gupta, Priyanka Gokhale","doi":"10.52403/ijhsr.20240606","DOIUrl":"https://doi.org/10.52403/ijhsr.20240606","url":null,"abstract":"Aim: To study the prevalence of De Quervain’s Tenosynovitis in cobblers.\u0000Objective: To assess De Quervain’s Tenosynovitis using the Finkelstein’s test in cobblers.\u0000Methodology: 350 subjects were selected according to the inclusion and exclusion criteria. A written informed consent was taken from the subjects, and were explained about the procedure. The Finkelstein test was performed in the dominant hand of the subject. A positive test indicated by a sharp shooting pain over the abductor pollicis longus and extensor pollicis brevis tendons at the wrist contributing to the painful entrapment of these two tendons. The data was collected and further evaluated statistically.\u0000Statistics & Results: Total 350 Cobblers were included in the study out of which 35% of total population assessed had De Quervain’s Tenosynovitis. When assessed within this positive result, 84% showed symptoms perceiving in right hand, and 16% in their left hand particularly based on the hand of dominance of the cobblers.\u0000Conclusions: The study concludes that the prevalence of De Quervain’s Tenosynovitis is fairly high in cobblers due to their self-limiting working pattern and requires ergonomic interventions and awareness about postural correction to prevent further musculoskeletal problems.\u0000\u0000Key words: De Quervain’s Tenosynovitis, Cobblers, Finkelstein Test, Work Related Musculoskeletal Dis-orders, Wrist Tendonitis.","PeriodicalId":14119,"journal":{"name":"International Journal of Health Sciences and Research","volume":" 37","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141368050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}