Pub Date : 2022-12-30DOI: 10.53771/ijlsra.2022.3.2.0134
R. Arul Prakasam, K. Sivakumar
The impact of anthropogenic activity of mattresses washing on the quality of two lotic water bodies of Cuddalore SIPCOT industries outlet water bodies two different stations were analysed. The industrial waste water currents battered along the Freshwater ecosystem near SIPCOT industries. Hence an attempt was made to record outlet water bodies two different stations were analysed. The water samples were collected during summer (April-June, 2021) and winter seasons (Oct-Dec 2021) and analysed for various physicochemical parameters. Decrease in dissolved oxygen concentrations along with tremendous increase in electrical conductivity in both the water bodies, was observed due to mattresses washing by using detergents. Heavy metals like lead, cadmium and nickel were absent throughout. The values of iron was increased while manganese was traced out after this activity. This proved that water quality was found to be hampered in both the stations. A total of 65 species of phytoplankton belonging to different taxonimic groups were identified. Among these, 25 species belong to Bacillariophyceae, 20 species to Chlorophyceae, 15 species to Cyanophyceae and 5 species to Euglenophyceae. The numerical superiority of phytoplankton reveals that Nitzschia sps. (6.66 x 103 units/1) is dominant in SIPCOT industries water outlet. The maximum value of Simpson index (SR) or species richness (0.55) was recorded in Cuddalore SIPCOT industry. The high value of species evenness index (J) was also recorded (0.69) in Cuddalore SIPCOT industry. The maximum value of Shannon’s overall index (H¢) of species diversity (1.38) was recorded in industrial outlet. Microcystis aeruginosa, Anabaena, Oscillatoria, Merismopedia, Aphanizomenon, Chlorella, Cosmarium, Scenedesmus, Closteridium, Navicula and Nitzschia were observed in two stations. These are pollution indicator species used for monitoring the environment.
{"title":"Influence of mattresses washing on the water quality and phytoplankton diversity in selected industrial outlets of Tamil Nadu","authors":"R. Arul Prakasam, K. Sivakumar","doi":"10.53771/ijlsra.2022.3.2.0134","DOIUrl":"https://doi.org/10.53771/ijlsra.2022.3.2.0134","url":null,"abstract":"The impact of anthropogenic activity of mattresses washing on the quality of two lotic water bodies of Cuddalore SIPCOT industries outlet water bodies two different stations were analysed. The industrial waste water currents battered along the Freshwater ecosystem near SIPCOT industries. Hence an attempt was made to record outlet water bodies two different stations were analysed. The water samples were collected during summer (April-June, 2021) and winter seasons (Oct-Dec 2021) and analysed for various physicochemical parameters. Decrease in dissolved oxygen concentrations along with tremendous increase in electrical conductivity in both the water bodies, was observed due to mattresses washing by using detergents. Heavy metals like lead, cadmium and nickel were absent throughout. The values of iron was increased while manganese was traced out after this activity. This proved that water quality was found to be hampered in both the stations. A total of 65 species of phytoplankton belonging to different taxonimic groups were identified. Among these, 25 species belong to Bacillariophyceae, 20 species to Chlorophyceae, 15 species to Cyanophyceae and 5 species to Euglenophyceae. The numerical superiority of phytoplankton reveals that Nitzschia sps. (6.66 x 103 units/1) is dominant in SIPCOT industries water outlet. The maximum value of Simpson index (SR) or species richness (0.55) was recorded in Cuddalore SIPCOT industry. The high value of species evenness index (J) was also recorded (0.69) in Cuddalore SIPCOT industry. The maximum value of Shannon’s overall index (H¢) of species diversity (1.38) was recorded in industrial outlet. Microcystis aeruginosa, Anabaena, Oscillatoria, Merismopedia, Aphanizomenon, Chlorella, Cosmarium, Scenedesmus, Closteridium, Navicula and Nitzschia were observed in two stations. These are pollution indicator species used for monitoring the environment.","PeriodicalId":14144,"journal":{"name":"International Journal of Life Science Research Archive","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75237759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The purpose of this study was to determine the prevalence of tobacco use and examine the differences in smoking-related knowledge, attitudes, and behaviors among university students in Morocco. A questionnaire was administered randomly to a representative sample of 810 students. The age range of the participants was 18 and 38 years and the mean age was 21 years. Participants were asked to complete self-administered questionnaires about sociodemographic characteristics, smoking-related family and university environments, smoking-related knowledge and attitudes, and smoking behaviors. A total of 800 students (98.77%) completed and returned the questionnaire. The prevalence of tobacco consumption was 17%. Smoking prevalence was higher for males and those aged between 18 and 20 25 years. Specialty and education were significantly associated with cigarette smoking behavior. The high prevalence of smoking among the student’s means that prevention measures are essential; this requires increasing self-esteem and evaluating intervention programs implemented before smoking the first cigarette.
{"title":"Smoking prevalence and associated factors among university students: Smoking-Related family behaviors, knowledge, attitudes and socioeconomic status","authors":"Aboufatima Rachida, Laadraoui Jawad, Moubtakir Soad, Sokar Zahra, Chait Abderrahman","doi":"10.53771/ijlsra.2022.3.2.0138","DOIUrl":"https://doi.org/10.53771/ijlsra.2022.3.2.0138","url":null,"abstract":"The purpose of this study was to determine the prevalence of tobacco use and examine the differences in smoking-related knowledge, attitudes, and behaviors among university students in Morocco. A questionnaire was administered randomly to a representative sample of 810 students. The age range of the participants was 18 and 38 years and the mean age was 21 years. Participants were asked to complete self-administered questionnaires about sociodemographic characteristics, smoking-related family and university environments, smoking-related knowledge and attitudes, and smoking behaviors. A total of 800 students (98.77%) completed and returned the questionnaire. The prevalence of tobacco consumption was 17%. Smoking prevalence was higher for males and those aged between 18 and 20 25 years. Specialty and education were significantly associated with cigarette smoking behavior. The high prevalence of smoking among the student’s means that prevention measures are essential; this requires increasing self-esteem and evaluating intervention programs implemented before smoking the first cigarette.","PeriodicalId":14144,"journal":{"name":"International Journal of Life Science Research Archive","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85086140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-30DOI: 10.53771/ijlsra.2022.3.2.0140
Rabi Housseini Malam Laminou, Saliou Ndiaye, Aliou Guissé, Diallo Djibril, Alioune Badara Dieye, Papa Saliou Sarr
This study was conducted in West-Central Senegal (Thies region) during two cropping seasons (2018 and 2019) to evaluate the effect of different doses of chemical fertilizer on soil chemical properties and the productivity of maize. Four treatments consisted of T0 (absolute control), RD (Recommended dose= 200 kg ha-1 NPK and 150 kg ha-1 urea), M1 (microdose 1= 41.66 kg ha-1 NPK and 41.66 kg ha-1 urea i.e. 0.5 g hill-1 NPK and 0.5 g urea), M2 (microdose 2= 83.33 kg ha-1 NPK and 41.66 kg ha-1 urea i.e. 1g hill-1 NPK and 0.5 g urea) and four maize varieties Gwana and Soror (composite varieties), Pan12 and Pan53 (hybrid varieties) were arranged in a split plot design with four replications. On average height of ear insertion was significantly increased with fertilizer microdosing. In 2018, microdose M1 achieved 89% and 26% of the grain yields recorded from T0 and RD, respectively. In line with grain yields, the amounts of soil elements exported in 2018 were higher in microdose in comparaison with RD and T0. A progressive decrease in soil pH and potassium is observed. Soil nitrogen decreased in 2018 but it increased in 2019, while an opposite trend was observed for soil phosphorus. The microdose technique was economically profitable with value-to-cost ratio of 9 and 4.47 for M1 and M2, respectively. It is concluded that the positive effect of fertilizer micro-dosing in improving maiz production depend on year, and on the better exploitation of soil nutrients.
本研究于2018年和2019年两个种植季在塞内加尔中西部(Thies地区)进行，旨在评估不同剂量化肥对土壤化学性质和玉米生产力的影响。四个治疗由T0(绝对控制),RD(推荐剂量= 200公斤是氮磷钾和150公斤农业尿素),M1(微剂量1 = 41.66公斤是氮磷钾和41.66公斤农业尿素即0.5 g hill-1氮磷钾和0.5 g尿素),M2(微剂量2 = 83.33公斤是农业尿素即氮磷钾和41.66公斤。1 g hill-1氮磷钾和0.5 g尿素)和四个玉米品种Gwana和Soror品种(组合),Pan12和Pan53(混合品种)被安排在一个分裂阴谋设计有四个复制。微量施肥显著提高了穗部平均高度。2018年，微剂量M1分别实现了T0和RD记录的粮食产量的89%和26%。与粮食产量一致，2018年出口土壤元素的微剂量量高于RD和T0。观察到土壤pH值和钾的逐渐下降。土壤氮在2018年呈下降趋势，但在2019年呈上升趋势，而土壤磷呈相反趋势。微剂量技术具有经济效益，M1和M2的价值成本比分别为9和4.47。结果表明，微量施肥对玉米增产的积极作用取决于年份，取决于土壤养分的更好利用。
{"title":"Effect of microdose chemical fertilization method on soil chemical properties and productivity of maize (Zea mays L.) in West-Central Senegal","authors":"Rabi Housseini Malam Laminou, Saliou Ndiaye, Aliou Guissé, Diallo Djibril, Alioune Badara Dieye, Papa Saliou Sarr","doi":"10.53771/ijlsra.2022.3.2.0140","DOIUrl":"https://doi.org/10.53771/ijlsra.2022.3.2.0140","url":null,"abstract":"This study was conducted in West-Central Senegal (Thies region) during two cropping seasons (2018 and 2019) to evaluate the effect of different doses of chemical fertilizer on soil chemical properties and the productivity of maize. Four treatments consisted of T0 (absolute control), RD (Recommended dose= 200 kg ha-1 NPK and 150 kg ha-1 urea), M1 (microdose 1= 41.66 kg ha-1 NPK and 41.66 kg ha-1 urea i.e. 0.5 g hill-1 NPK and 0.5 g urea), M2 (microdose 2= 83.33 kg ha-1 NPK and 41.66 kg ha-1 urea i.e. 1g hill-1 NPK and 0.5 g urea) and four maize varieties Gwana and Soror (composite varieties), Pan12 and Pan53 (hybrid varieties) were arranged in a split plot design with four replications. On average height of ear insertion was significantly increased with fertilizer microdosing. In 2018, microdose M1 achieved 89% and 26% of the grain yields recorded from T0 and RD, respectively. In line with grain yields, the amounts of soil elements exported in 2018 were higher in microdose in comparaison with RD and T0. A progressive decrease in soil pH and potassium is observed. Soil nitrogen decreased in 2018 but it increased in 2019, while an opposite trend was observed for soil phosphorus. The microdose technique was economically profitable with value-to-cost ratio of 9 and 4.47 for M1 and M2, respectively. It is concluded that the positive effect of fertilizer micro-dosing in improving maiz production depend on year, and on the better exploitation of soil nutrients.","PeriodicalId":14144,"journal":{"name":"International Journal of Life Science Research Archive","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91553008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-30DOI: 10.53771/ijlsra.2022.3.2.0151
Muyingo Ali, Mukadasi Buyinza
The fisheries of Lake Victoria have undergone a dramatic transformation during the last two decades. From being a locally based fishery with little intervention and capital investment from outside, the present fishery is dominated by national and international capital penetrating the industry. It is the explosion in the growth of Nile perch and the strong demand developed for this fish in the global markets, which have transformed the fisheries of Lake Victoria. This study evaluated the effect of social demographics of the fishing community and the unsustainable extraction and fish handling at Rukondo Village in Buikwe District. The specific objectives of the study were; to document the social-demographics of the fishing community; examine the fish handling and processing methods; and estimate the effect and damage on fish during extraction and handling methods. The study used descriptive longitudinal approach, both qualitative and quantitative methods of data collection was used to collect data from a sample of 2 fishery zones with 50 household per local private sector approximately to 70 households with in the area. Questionnaires were administered to the selected fishermen and fish traders who were selected using purposive and stratified simple random sampling. The information obtained was coded and entered in a database utilising the software package; the data were then converted into SPSS V.8.0 system files for processing and preliminary analysis. The study shows that tilapia and Nile perch are the common fish species traded in the study area. Some fishers who resort to bad fishing methods do it for their survival since they are poor, unemployed and cannot afford the legal gears, which are too expensive for them. The lack of a comprehensive law on fishing is also making it possible for illegal nets and poison to be used. The policy recommendation is that the government should focus on establishment and new extraction and handling techniques in fish farming which will help the majority of the fishermen involved in fishing out of the poverty cycle due to high profit margins accruing from fish farming. The loses and damage should be better integrated into the Fisheries Resource Co-management institutions on the Lake Victoria so as to provide technical advice and affordable solutions to fishermen in order to improve on the fish extraction and handling techniques.
{"title":"The social-demographics and effects of unsustainable extraction and fish handling in Rukundo village, Buikwe District, Central Uganda","authors":"Muyingo Ali, Mukadasi Buyinza","doi":"10.53771/ijlsra.2022.3.2.0151","DOIUrl":"https://doi.org/10.53771/ijlsra.2022.3.2.0151","url":null,"abstract":"The fisheries of Lake Victoria have undergone a dramatic transformation during the last two decades. From being a locally based fishery with little intervention and capital investment from outside, the present fishery is dominated by national and international capital penetrating the industry. It is the explosion in the growth of Nile perch and the strong demand developed for this fish in the global markets, which have transformed the fisheries of Lake Victoria. This study evaluated the effect of social demographics of the fishing community and the unsustainable extraction and fish handling at Rukondo Village in Buikwe District. The specific objectives of the study were; to document the social-demographics of the fishing community; examine the fish handling and processing methods; and estimate the effect and damage on fish during extraction and handling methods. The study used descriptive longitudinal approach, both qualitative and quantitative methods of data collection was used to collect data from a sample of 2 fishery zones with 50 household per local private sector approximately to 70 households with in the area. Questionnaires were administered to the selected fishermen and fish traders who were selected using purposive and stratified simple random sampling. The information obtained was coded and entered in a database utilising the software package; the data were then converted into SPSS V.8.0 system files for processing and preliminary analysis. The study shows that tilapia and Nile perch are the common fish species traded in the study area. Some fishers who resort to bad fishing methods do it for their survival since they are poor, unemployed and cannot afford the legal gears, which are too expensive for them. The lack of a comprehensive law on fishing is also making it possible for illegal nets and poison to be used. The policy recommendation is that the government should focus on establishment and new extraction and handling techniques in fish farming which will help the majority of the fishermen involved in fishing out of the poverty cycle due to high profit margins accruing from fish farming. The loses and damage should be better integrated into the Fisheries Resource Co-management institutions on the Lake Victoria so as to provide technical advice and affordable solutions to fishermen in order to improve on the fish extraction and handling techniques.","PeriodicalId":14144,"journal":{"name":"International Journal of Life Science Research Archive","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74569349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-30DOI: 10.53771/ijlsra.2022.3.2.0141
Amira H Mahmoud, Abdelwahab E Younes
Objective: This study has been conducted to determine Patterns of infections and antimicrobial susceptibility in elderly patients admitted to long term care at a tertiary care hospital in Saudi Arabia, Eastern province to guide rationale for antibiotic use and prevent resistance. Materials & Methods: A total of 100 specimens were collected from100 elderly patients ≥ 60years, both males and females admitted to long term care in a tertiary hospital in Dammam city, Eastern province, Saudi Arabia during the year 2022. Collected specimens included forty urine samples , forty sputum samples and twenty swabs from infected pressure ulcers .All collected specimens were sent for bacterial culture and sensitivity, bacterial species were determined by conventional methods and disk diffusion was used to determine the antimicrobial susceptibility pattern of the bacteria isolates after 48 hours incubation. Results: Out of the 100 cultured specimens, 118 pathogens were detected in the whole sample where Gram-negative bacteria: primarily, Klebsiella pneumoniae (32.2%) followed by pseudomonas aeruginosa (20.3%) then Acinetobacter bumannii (14.4%) represented the most prevalent pathogens. High percentage of multidrug resistant pathogens (MDR) was detected mostly among Acinetobacter 60% followed by pseudomonas 35% then E-coli 33%. Antibiotic sensitivity was variable among different pathogens, gram negative pathogens sensitivity was generally high mainly to amino glycosides and carbapenems groups.
{"title":"Patterns of infections and antimicrobial susceptibility in elderly patients: Long term care based study","authors":"Amira H Mahmoud, Abdelwahab E Younes","doi":"10.53771/ijlsra.2022.3.2.0141","DOIUrl":"https://doi.org/10.53771/ijlsra.2022.3.2.0141","url":null,"abstract":"Objective: This study has been conducted to determine Patterns of infections and antimicrobial susceptibility in elderly patients admitted to long term care at a tertiary care hospital in Saudi Arabia, Eastern province to guide rationale for antibiotic use and prevent resistance. Materials & Methods: A total of 100 specimens were collected from100 elderly patients ≥ 60years, both males and females admitted to long term care in a tertiary hospital in Dammam city, Eastern province, Saudi Arabia during the year 2022. Collected specimens included forty urine samples , forty sputum samples and twenty swabs from infected pressure ulcers .All collected specimens were sent for bacterial culture and sensitivity, bacterial species were determined by conventional methods and disk diffusion was used to determine the antimicrobial susceptibility pattern of the bacteria isolates after 48 hours incubation. Results: Out of the 100 cultured specimens, 118 pathogens were detected in the whole sample where Gram-negative bacteria: primarily, Klebsiella pneumoniae (32.2%) followed by pseudomonas aeruginosa (20.3%) then Acinetobacter bumannii (14.4%) represented the most prevalent pathogens. High percentage of multidrug resistant pathogens (MDR) was detected mostly among Acinetobacter 60% followed by pseudomonas 35% then E-coli 33%. Antibiotic sensitivity was variable among different pathogens, gram negative pathogens sensitivity was generally high mainly to amino glycosides and carbapenems groups.","PeriodicalId":14144,"journal":{"name":"International Journal of Life Science Research Archive","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83506187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-30DOI: 10.53771/ijlsra.2022.3.2.0146
Ohad Avny, Dorith Shaham, Odelia Ben Harush, Meni Koslowsky, Yehudah Fraenkel
Balint training was originally developed as a means for improving the doctor-patient relationship. In recent years Balint groups have become part of medical students' training during their clinical clerkships. The purpose of the study was to explore whether gender and age differences affect medical students' perceptions of Balint training. A total of 72 students in the fourth year at the Hebrew University Medical School completed a questionnaire on their perception of the importance of Balint training. A significant difference by gender was found but not for age. As the percentage of female medical students is expected to increase over the next few years, the inclusion of Balint training in schools that have not yet included it in their curriculum would be appropriate.
{"title":"Balint training in medical school: Differences in perception by age and gender","authors":"Ohad Avny, Dorith Shaham, Odelia Ben Harush, Meni Koslowsky, Yehudah Fraenkel","doi":"10.53771/ijlsra.2022.3.2.0146","DOIUrl":"https://doi.org/10.53771/ijlsra.2022.3.2.0146","url":null,"abstract":"Balint training was originally developed as a means for improving the doctor-patient relationship. In recent years Balint groups have become part of medical students' training during their clinical clerkships. The purpose of the study was to explore whether gender and age differences affect medical students' perceptions of Balint training. A total of 72 students in the fourth year at the Hebrew University Medical School completed a questionnaire on their perception of the importance of Balint training. A significant difference by gender was found but not for age. As the percentage of female medical students is expected to increase over the next few years, the inclusion of Balint training in schools that have not yet included it in their curriculum would be appropriate.","PeriodicalId":14144,"journal":{"name":"International Journal of Life Science Research Archive","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91445570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-30DOI: 10.53771/ijlsra.2022.3.2.0135
R. Xavier Arulappa, M. Jerubin Welsingh, M. Lavanya, T. Sterlin, M. Viji, P. Karuppasamy
The aim of the present work was to develop and validate a simple UV Spectroscopic method for the determination of Nimesulide, which is the inhibitor of prostaglandin synthesis from arachidonic acid and platelet aggregation. It has the ability to exert analgesic and anti-inflammatory actions through various mechanisms (ie, COX independent pathways) and also it inhibits the release of tumour necrosis factor (TNFα) and interleukins, and stops the release of histamine from mast cells and reduce the synthesis of platelet activating factor (PAF) from the basophil cells. The UV visible Spectrophotometric analysis was performed using systronics UV-Spectrophotometer 2704 X visible double beam by using solvent KOH. Detection was performed at a wavelength of 395nm. Method validation was carried out according to ICH Q2R1 guidelines by taking the parameters such as accuracy, linearity, precision, ruggedness, and robustness, LOD and LOQ. The UV spectrophotometric was found linear in the range 5- 25µg/ml. The method was rugged and robust with % relative standard deviation less than 2. The extraction recoveries was found to be higher than 99.19% in all experimental conditions. Based upon the performance characteristics, the proposed method was found accurate, precise, rapid and suitable for the determination of nimesulide for routine analysis. The aim of the present work was to develop and validate a simple UV Spectroscopic method for the determination of Nimesulide, which is the inhibitor of prostaglandin synthesis from arachidonic acid and platelet aggregation. It has the ability to exert analgesic and anti-inflammatory actions through various mechanisms (ie, COX independent pathways) and also it inhibits the release of tumour necrosis factor (TNFα) and interleukins, and stops the release of histamine from mast cells and reduce the synthesis of platelet activating factor (PAF) from the basophil cells. The UV visible Spectrophotometric analysis was performed using systronics UV-Spectrophotometer 2704 X visible double beam by using solvent KOH. Detection was performed at a wavelength of 395nm. Method validation was carried out according to ICH Q2R1 guidelines by taking the parameters such as accuracy, linearity, precision, ruggedness, and robustness, LOD and LOQ. The UV spectrophotometric was found linear in the range 5- 25µg/ml. The method was rugged and robust with % relative standard deviation less than 2. The extraction recoveries was found to be higher than 99.19% in all experimental conditions. Based upon the performance characteristics, the proposed method was found accurate, precise, rapid and suitable for the determination of nimesulide for routine analysis.
{"title":"Development and Validation of UV-Visible spectroscopic method for estimation of Nimesulide in bulk and its pharmaceutical formulation","authors":"R. Xavier Arulappa, M. Jerubin Welsingh, M. Lavanya, T. Sterlin, M. Viji, P. Karuppasamy","doi":"10.53771/ijlsra.2022.3.2.0135","DOIUrl":"https://doi.org/10.53771/ijlsra.2022.3.2.0135","url":null,"abstract":"The aim of the present work was to develop and validate a simple UV Spectroscopic method for the determination of Nimesulide, which is the inhibitor of prostaglandin synthesis from arachidonic acid and platelet aggregation. It has the ability to exert analgesic and anti-inflammatory actions through various mechanisms (ie, COX independent pathways) and also it inhibits the release of tumour necrosis factor (TNFα) and interleukins, and stops the release of histamine from mast cells and reduce the synthesis of platelet activating factor (PAF) from the basophil cells. The UV visible Spectrophotometric analysis was performed using systronics UV-Spectrophotometer 2704 X visible double beam by using solvent KOH. Detection was performed at a wavelength of 395nm. Method validation was carried out according to ICH Q2R1 guidelines by taking the parameters such as accuracy, linearity, precision, ruggedness, and robustness, LOD and LOQ. The UV spectrophotometric was found linear in the range 5- 25µg/ml. The method was rugged and robust with % relative standard deviation less than 2. The extraction recoveries was found to be higher than 99.19% in all experimental conditions. Based upon the performance characteristics, the proposed method was found accurate, precise, rapid and suitable for the determination of nimesulide for routine analysis. The aim of the present work was to develop and validate a simple UV Spectroscopic method for the determination of Nimesulide, which is the inhibitor of prostaglandin synthesis from arachidonic acid and platelet aggregation. It has the ability to exert analgesic and anti-inflammatory actions through various mechanisms (ie, COX independent pathways) and also it inhibits the release of tumour necrosis factor (TNFα) and interleukins, and stops the release of histamine from mast cells and reduce the synthesis of platelet activating factor (PAF) from the basophil cells. The UV visible Spectrophotometric analysis was performed using systronics UV-Spectrophotometer 2704 X visible double beam by using solvent KOH. Detection was performed at a wavelength of 395nm. Method validation was carried out according to ICH Q2R1 guidelines by taking the parameters such as accuracy, linearity, precision, ruggedness, and robustness, LOD and LOQ. The UV spectrophotometric was found linear in the range 5- 25µg/ml. The method was rugged and robust with % relative standard deviation less than 2. The extraction recoveries was found to be higher than 99.19% in all experimental conditions. Based upon the performance characteristics, the proposed method was found accurate, precise, rapid and suitable for the determination of nimesulide for routine analysis.","PeriodicalId":14144,"journal":{"name":"International Journal of Life Science Research Archive","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74541240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-30DOI: 10.53771/ijlsra.2022.3.2.0142
Neha Atkaan, Mrinalini, Seema Bukhari
Stem cells are cells that have the ability to differentiate into any cell type in the body. This makes them a powerful tool for treating a variety of diseases and injuries. There are two main types of stem cells: embryonic stem cells and adult stem cells. Embryonic stem cells are derived from embryos, while adult stem cells are found in adult tissues. Embryonic stem cells can differentiate into any cell type in the body, making them a powerful tool for treating various diseases and injuries. However, their use is limited by ethical concerns and the risk of rejection by the body. Following review article will discuss some new fields in which these stem cells and their modifications can be used.
{"title":"Stem cell in dentistry: Today and tomorrow","authors":"Neha Atkaan, Mrinalini, Seema Bukhari","doi":"10.53771/ijlsra.2022.3.2.0142","DOIUrl":"https://doi.org/10.53771/ijlsra.2022.3.2.0142","url":null,"abstract":"Stem cells are cells that have the ability to differentiate into any cell type in the body. This makes them a powerful tool for treating a variety of diseases and injuries. There are two main types of stem cells: embryonic stem cells and adult stem cells. Embryonic stem cells are derived from embryos, while adult stem cells are found in adult tissues. Embryonic stem cells can differentiate into any cell type in the body, making them a powerful tool for treating various diseases and injuries. However, their use is limited by ethical concerns and the risk of rejection by the body. Following review article will discuss some new fields in which these stem cells and their modifications can be used.","PeriodicalId":14144,"journal":{"name":"International Journal of Life Science Research Archive","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84184779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-30DOI: 10.53771/ijlsra.2022.3.2.0147
Alessandro Finzi, Pietro Battistini
In the paretic left hand of an eighty years old man only fingers flexion was voluntary possible and movement of extension, adduction or abduction needed mechanical help. After ten years, when fingers had progressively slightly more curled up, the subject discovered that voluntary movements of adduction and abduction became easily possible just by pressing the hand on a flat surface. Persistent voluntary hand motility was then partially obtained through specific self-trained exercise. The increase in the abduction angle was easily measured with a proctor and this is proposed as a simple clinical test to assess the improvement due to training. The case is analytically described.
{"title":"Partial persistent recovery of voluntary motility by auto-training in a clinical case of fingers paresis: A case report","authors":"Alessandro Finzi, Pietro Battistini","doi":"10.53771/ijlsra.2022.3.2.0147","DOIUrl":"https://doi.org/10.53771/ijlsra.2022.3.2.0147","url":null,"abstract":"In the paretic left hand of an eighty years old man only fingers flexion was voluntary possible and movement of extension, adduction or abduction needed mechanical help. After ten years, when fingers had progressively slightly more curled up, the subject discovered that voluntary movements of adduction and abduction became easily possible just by pressing the hand on a flat surface. Persistent voluntary hand motility was then partially obtained through specific self-trained exercise. The increase in the abduction angle was easily measured with a proctor and this is proposed as a simple clinical test to assess the improvement due to training. The case is analytically described.","PeriodicalId":14144,"journal":{"name":"International Journal of Life Science Research Archive","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82331824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-30DOI: 10.53771/ijlsra.2022.3.2.0149
Nurul Islam, Siddhartha Saha
NIH (National Institute of Health) catheter is a side hole angiographic catheter. The angiographic catheter can be used equally well in both sampling and pressure recordings beyond angiography. Side hole catheter like NIH angiographic catheter is not used routinely for crossing stenotic valve with a wire through it. In a resource limited set up with less availability of catheters, NIH catheter can be used beyond the convention- to cross a stenotic valve through a J tip wire in it. In our Institution we have used NIH catheter with a J tip wire in multiple times, for crossing the stenosed pulmonary valve while doing Balloon pulmonary valvuloplasty. The rest of the procedure is done as per standard protocol. Though NIH catheter is having only side holes, it can also be used to cross a stenosed valve in difficult situation or resource limited set up.
{"title":"Unconventional use of NIH angiographic catheter in resource limited setup: A brief experience","authors":"Nurul Islam, Siddhartha Saha","doi":"10.53771/ijlsra.2022.3.2.0149","DOIUrl":"https://doi.org/10.53771/ijlsra.2022.3.2.0149","url":null,"abstract":"NIH (National Institute of Health) catheter is a side hole angiographic catheter. The angiographic catheter can be used equally well in both sampling and pressure recordings beyond angiography. Side hole catheter like NIH angiographic catheter is not used routinely for crossing stenotic valve with a wire through it. In a resource limited set up with less availability of catheters, NIH catheter can be used beyond the convention- to cross a stenotic valve through a J tip wire in it. In our Institution we have used NIH catheter with a J tip wire in multiple times, for crossing the stenosed pulmonary valve while doing Balloon pulmonary valvuloplasty. The rest of the procedure is done as per standard protocol. Though NIH catheter is having only side holes, it can also be used to cross a stenosed valve in difficult situation or resource limited set up.","PeriodicalId":14144,"journal":{"name":"International Journal of Life Science Research Archive","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81197944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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