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Red blood cell indices and red blood cell morphology in the haematological evaluation of patients: Study from a tribal based hospital in rural India 红血球指数和红血球形态学在病人血液学评估中的应用:来自印度农村部落医院的研究
Pub Date : 2021-01-01 DOI: 10.5455/ijmsph.2021.06047202101082021
M. Sarkar, Anuradha Sinha, A. Majumdar, Anindya Adhikari, Goutam Dey
so as to avoid hazards of transfusion. Background: Anaemia causes impaired oxygen delivery to tissues. The first investigation done in anaemia is blood for haemoglobin%(Hb%). It can be reported within minutes using automated analyser. Peripheral blood smear (PBS) examination for assessment of red cell morphology is advised to evaluate the effect of anaemia on patient’s health. Now-a-days, automated analysers are supplied in remote hospital set-up also. But analyser results must be justified with blood smear examination findings. Objectives: General: To find out the spectrum of Hb concentration among indoor patients; Specific: To find out whether analyser derived red cell indices correspond with red cell morphology on PBS. Materials and Methods: Observational, cross-sectional, descriptive study conducted in the pathology department of a tribal based hospital. After institutional ethics committee permission the study was conducted for 1 year duration among indoor patients selecting the first complete haemogram report after admission. Hb values were categorised into 4 sub-groups (≥12 g/dl, 10–<12 g/dl, 7–<10 g/dl, <7 g/dl). Red cell indices were derived from analyser. Blood smear stained by Leishman-Giemsa was examined under light microscope. Data was analysed at the end of the study using Microsoft Excel software 2010. Results: Among 478 total cases 39.53% were male, 60.46% female (Male:Female ratio 1:1.53). 50% of total population had Hb% ≥12 g/dl which constituted 69.84% of the male and 37.02% of the female cases. Females were more in number to have abnormal red cell morphology (23.53%) compared to male (19.05%). Red cell index abnormality was almost equal in male (58.20%) and female (59.52%). More male patients had red cell morphology abnormality (54.38%) than female (34.62%) at Hb level <12g/dl. Conclusion: Red cell morphology must accompany all cases of haemogram reporting.
从而避免输血的危害。背景:贫血导致组织供氧受损。在贫血中做的第一个调查是血红蛋白%(Hb%)。使用自动分析仪可以在几分钟内报告。建议外周血涂片(PBS)检查红细胞形态,以评估贫血对患者健康的影响。如今,远程医院也提供自动分析仪。但分析结果必须与血液涂片检查结果相一致。目的:一般:了解室内患者Hb浓度谱;特异性:检测分析仪得出的红细胞指标是否与PBS上的红细胞形态相符。材料和方法:观察性、横断面、描述性研究在一家部落医院的病理科进行。经机构伦理委员会许可,在住院患者中选择入院后第一份完整的血图报告进行为期1年的研究。Hb值分为4个亚组(≥12g /dl, 10 - < 12g /dl, 7 - < 10g /dl, < 7g /dl)。红细胞指数由分析仪得出。光镜下检查利什曼-吉姆沙染色血涂片。在研究结束时,使用Microsoft Excel软件2010对数据进行分析。结果:478例患者中男性占39.53%,女性占60.46%(男女比例为1:1.53)。50%的人群Hb%≥12 g/dl,其中男性占69.84%,女性占37.02%。女性(23.53%)红细胞形态异常多于男性(19.05%)。红细胞指数异常在男性(58.20%)和女性(59.52%)中几乎相等。Hb <12g/dl时,男性患者红细胞形态异常(54.38%)多于女性患者(34.62%)。结论:所有病例的血象报告必须附有红细胞形态学。
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引用次数: 0
Impact of climatic parameters on coronavirus disease 2019 pandemic progression in India: Analysis and prediction 气候参数对2019年印度冠状病毒病大流行进展的影响:分析与预测
Pub Date : 2021-01-01 DOI: 10.5455/IJMSPH.2021.07121202001052021
N. Deyal, V. Tiwari, N. Bisht
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引用次数: 0
Knowledge, attitude, and drug resistance preventive behaviors of high school students in Bangkok 曼谷地区高中生的知识、态度与耐药预防行为
Pub Date : 2021-01-01 DOI: 10.5455/jmsph.2021.09102202111102021
Chanadee Hirunpath
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引用次数: 0
Knowledge, understanding, attitude, and preventive behavior toward COVID-19: A study among high school students in Loei Pittayakom, Thailand 对COVID-19的知识、理解、态度和预防行为:泰国Loei Pittayakom高中学生的研究
Pub Date : 2021-01-01 DOI: 10.5455/ijmsph.2021.08078202127102021
Phitsiree Phengmeesri
Background: COVID-19 pandemic has affected humanity in several aspects of life. Not only create health problems, but also economic and social problems. To cope with this pandemic, we need to know and understand how to have the COVID-19 preventive behavior. Hence, this study will be focusing on factors that influence people to have COVID-19 preventive behavior. Objectives: The aim of this study is to assess knowledge, attitude, and COVID-19 preventive behavior of high school students. Materials and Methods: The study was conducted using a questionnaire. A total of 325 students participated. Knowledge, attitude without presence of rules, and attitude with presence of rules toward COVID-19 preventive behavior were assessed. Independent t-test and analysis of variance were used to analyze differences between outcomes and socio-demographic. COVID-19 preventive behavior was analyzed by a generalized linear model. Results: Students revealed a good level of COVID-19 related knowledge, correctly answering 4.48 (standard deviation [SD] = 0.70) questions in a total of 5, good levels of attitude both without and with the presence of rules, average score was 11.05 (SD = 1.16) of four questions and 15.86 (SD = 2.07) of six questions, respectively, and a good level of COVID-19 preventive behavior, the average scores at 44.28 (SD = 6.68), in a total of 11 questions. Conclusion: This study revealed a good level of knowledge, attitude both without and with the presence of rules and COVID-19 preventive behavior among high school students at Loei Pittayakom School, Thailand. Mainly, the factor that may influence them to get a high score in all four sections is staying active with news and the latest information presented on the internet. In addition, the study demonstrated that there was a relationship between attitude with the presence of rules and COVID-19 preventive behavior. Therefore, having regulations can lead to having preventive behavior.
背景:2019冠状病毒病大流行对人类生活的几个方面产生了影响。不仅造成健康问题,还造成经济和社会问题。为了应对这场大流行,我们需要了解和了解如何采取COVID-19预防行为。因此,这项研究将重点关注影响人们采取COVID-19预防行为的因素。目的:本研究的目的是评估高中生的COVID-19预防知识、态度和行为。材料与方法:采用问卷调查法进行研究。共有325名学生参与。评估对COVID-19预防行为的知识、不存在规则的态度和存在规则的态度。采用独立t检验和方差分析分析结果与社会人口学差异。采用广义线性模型分析COVID-19预防行为。结果:学生对新冠肺炎相关知识水平较好,共5道题中正确率为4.48题(标准差[SD] = 0.70);对有无规则的态度水平较好,4道题中平均分为11.05分(SD = 1.16), 6道题中平均分为15.86分(SD = 2.07);对新冠肺炎预防行为水平较好,共11道题中平均分为44.28分(SD = 6.68)。结论:本研究揭示了泰国Loei Pittayakom学校的高中生在没有和有规则的情况下的良好知识水平、态度和COVID-19预防行为。主要,可能影响他们在所有四个部分获得高分的因素是保持活跃的新闻和最新的信息呈现在互联网上。此外,该研究还表明,态度与规则的存在与COVID-19预防行为之间存在关系。因此,制定规章制度可以导致预防行为。
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引用次数: 0
A study on coverage of isoniazid chemoprophylaxis among the household contacts of smear positive pulmonary tuberculosis cases aged <6 years under Revised National Tuberculosis Control Programme 修订国家结核病控制规划对6岁以下涂阳肺结核家庭接触者异烟肼化学预防覆盖率的研究
Pub Date : 2021-01-01 DOI: 10.5455/IJMSPH.2021.01011202103062021
Babu Dilip, S Anurupa, Satish Ghatage, Swathi S Aithal
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引用次数: 0
Knowledge, attitudes, and preventive behaviors toward coronavirus disease-19: A study among high school students in Bangkok 对冠状病毒疾病的知识、态度和预防行为19:曼谷高中生的一项研究
Pub Date : 2021-01-01 DOI: 10.5455/IJMSPH.2021.04033202126042021
Tawan Petpaiboon
Background: Breaking the chain of infection is the process that is controlled by the infection control and contact tracing to inhibit infections of pathogens in more people which can be done by stopping the cycle of chain of infection. To prevent coronavirus disease (COVID)-19 from further spreading, breaking the chain of infection is required. In addition, in the chain of infection, the last key point is the factors that affect the behavior in disease transmission prevention of COVID-19. Research has shown that good knowledge and a positive attitude have contributed to a behavior that would prevent this disease. One of the most important actions that need to be taken to break the chain of infection is to set a healthy behavior in each individual. Objectives: The purpose of this study was to assess knowledge, attitudes, and behaviors about COVID-19 among high school students in Bangkok. Materials and Methods: The study was conducted using a questionnaire. A total of 177 students participated. COVID-19-related knowledge, attitudes toward COVID-19, and preventive behaviors were assessed. Differences between outcomes and sociodemographic were analyzed through independent t-test and the ANOVA. Preventive behaviors were analyzed by a generalized linear model.
背景:阻断感染链是指通过感染控制和接触者追踪控制的过程,通过阻断感染链循环来抑制病原体在更多人中的感染。为了防止冠状病毒病(COVID -19)进一步传播,需要打破感染链。此外,在感染链中,最后一个关键点是影响COVID-19疾病传播预防行为的因素。研究表明,良好的知识和积极的态度有助于预防这种疾病的行为。打破感染链需要采取的最重要的行动之一是在每个人身上树立健康的行为习惯。目的:本研究的目的是评估曼谷高中学生对COVID-19的知识、态度和行为。材料与方法:采用问卷调查法进行研究。共有177名学生参加。对新冠肺炎相关知识、态度和预防行为进行评估。通过独立t检验和方差分析分析结果与社会人口学的差异。采用广义线性模型分析预防行为。
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引用次数: 4
Noncommunicable disease risk profile of urban women in Indore city, India 印度印多尔市城市妇女的非传染性疾病风险概况
Pub Date : 2021-01-01 DOI: 10.4103/JNCD.JNCD_91_20
D. Bachani, Amanda Stevens, K. Anand, R. Amarchand
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引用次数: 0
A study of serum magnesium level in type 2 diabetes mellitus and its association with glycemic control and its complications 2型糖尿病患者血清镁水平与血糖控制及其并发症的关系
Pub Date : 2021-01-01 DOI: 10.4103/JNCD.JNCD_53_20
Arti Muley, Kalpesh Moradiya
Context: Diabetes is a major public health problem with increasing morbidity due to complications. There have been reports regarding the association of serum magnesium (S. Mg) with diabetic complications but they are few and inconclusive. Aims: The aim was to find the status of S. Mg in patients of type 2 diabetes mellitus (type 2 DM) and study association of S. Mg with glycemic control and diabetic complications. Settings and Design: This was a cross-sectional observational study carried out in a tertiary care hospital in rural area. Subjects and Methods: All patients of type 2 DM were included. Detailed history was taken and all were subjected to routine investigations and S. Mg level. Patients were also screened for complications of diabetes. Statistical Analysis Used: Data were analyzed for any association between S. Mg levels and diabetic control (hemoglobin A1c [HbA1c]) and also for the correlation with diabetic retinopathy and nephropathy. Results: Mean S. Mg was significantly less in patients having uncontrolled diabetes (HbA1c ≥7%) as compared to those with HbA1c Conclusions: Hypomagnesemia is associated with uncontrolled HbA1c and diabetic complications. Routine monitoring and correction of S. Mg levels in type 2 diabetes patients may help in better control of HbA1c and delaying progression to retinopathy and nephropathy.
背景:糖尿病是一个主要的公共卫生问题,由于并发症,发病率不断上升。有关于血清镁(S. Mg)与糖尿病并发症的关系的报道,但它们很少且不确定。目的:了解2型糖尿病(2型糖尿病)患者中s - Mg的状况,并研究s - Mg与血糖控制和糖尿病并发症的关系。背景和设计:本研究是在农村地区一家三级医院进行的横断面观察性研究。对象和方法:纳入所有2型糖尿病患者。详细记录病史,并进行常规调查和S. Mg水平检查。患者还接受了糖尿病并发症的筛查。统计学分析使用:分析s - Mg水平与糖尿病控制(血红蛋白A1c [HbA1c])之间的关系以及与糖尿病视网膜病变和肾病的关系。结论:低镁血症与未控制的HbA1c和糖尿病并发症相关。2型糖尿病患者常规监测和纠正s - Mg水平可能有助于更好地控制HbA1c,延缓视网膜病变和肾病的进展。
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引用次数: 1
Newborn screening by enzyme immunoassay using dry blood spot for diagnosis of metabolic disorders 干血点酶免疫法筛查新生儿代谢性疾病的研究
Pub Date : 2021-01-01 DOI: 10.5455/ijmsph.2021.04032202119062021
Fahima H, D. S, Chindhiha S, S. Vincy, Chandrasekar M, S. K.
Background: Newborn screening (NBS) is the test used to diagnosis the metabolic and other disorders within 72 h of birth. The early identification of the disorder helps in early treatment which prevents neonates from life-threatening health problem, mental retardation, and serious lifelong disabilities. Objectives: Universal NBS using heel-prick dried blood spot (DBS) samples has become an integral part of public health system in developed countries. There are about 99.9% of newborns that are screened every year in western countries. Whereas, in India the less 1% of newborns are screened due to the ignorance and not knowing the importance of NBS. Very few states in India had started the program in government. Awareness among the professionals and public about the NBS has to be created and extended. Materials and Methods: The Newborn DBS samples were received from Government Vellore Medical College Hospital, Government Hospitals at Tirupattur, Gudiyatham and 104 primary health centers. Samples should be collected within 72 h from the newborn. Screening of human thyroid-stimulating hormones, 17-OHP, glucose-6-phosphate dehydrogenase, Galactose, and IRT are done using the Enzyme Immunoassay (EIA) method using their respective conjugate, Conjugate Diluent, Substrate solution TMB Chromogen, washing solution 10 ×, 1 × 50 ml Stopping solution and measured using micro plate photometer. Point of care testing (POCT) requires only 1 drop (10 μL) of blood from the pricked heel of the baby, and it can be performed 5–10 min at bedside. Results: NBS is done using the EIA method which reports between 8 and 12 days. Comparing point of care (POCT) with EIA, the results of POCT are compatible and satisfactory and it completes in 5 days. Conclusion: The proper implementation of “point of care” testing will help to identify the positive cases early and prevents the baby from permanent disability.
背景:新生儿筛查(NBS)是用于诊断出生72小时内代谢和其他疾病的检查。这种疾病的早期识别有助于早期治疗,从而防止新生儿出现危及生命的健康问题、智力迟钝和严重的终身残疾。目的:采用足跟刺干血斑(DBS)样本进行全民血检已成为发达国家公共卫生系统的重要组成部分。在西方国家,每年约有99.9%的新生儿接受筛查。然而,在印度,由于无知和不知道国家统计局的重要性,只有不到1%的新生儿接受了筛查。印度很少有邦在政府中启动了这个项目。专业人士和公众对国家统计局的认识必须建立和扩大。材料与方法:新生儿DBS样本来自政府Vellore医学院医院、Tirupattur、Gudiyatham的政府医院和104个初级卫生中心。应在72小时内从新生儿身上采集样本。人促甲状腺激素、17-OHP、葡萄糖-6-磷酸脱氢酶、半乳糖和IRT的筛选采用酶免疫分析法(EIA),分别使用它们各自的偶联物、偶联稀释剂、底物溶液TMB显色剂、洗涤液10 ×、停止液1 × 50 ml进行筛选,并用微板光度计进行测定。POCT (Point of care testing)只需从婴儿刺破的足跟处滴1滴(10 μL)血,可在床边进行5 ~ 10分钟。结果:国家统计局采用EIA方法,报告时间为8 - 12天。点疗(POCT)与环评(EIA)比较,结果一致,满意,在5天内完成。结论:正确实施“护理点”检测有助于早期发现阳性病例,防止婴儿终身残疾。
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引用次数: 0
Knowledge, attitude, and drug resistance preventive behavior among Thai people:A cross-sectional online study in Thailand 泰国人的知识、态度和耐药预防行为:泰国的一项横断面在线研究
Pub Date : 2021-01-01 DOI: 10.5455/ijmsph.2021.08081202113082021
Sujimon Mungkalarungsi, Kanokorn Tangjonrach, Damisa Chaemnapa, Pumin Wimuttigosol, Nattanicha Buttamee, Jirapat Anakewat, Sittha Phadungyan, Cindy Shainwald, Navaporn Apichaidejudom, Sadhu Wongsaroj
Background: Many Thai people have misconceptions about antibiotics, such as an understanding that antibiotics are an anti-inflammatory drug. It has led to the misconception that the use of this drug will make existing disease heals faster because the drug is going to treat or cure inflammation. Many people do not know that bacteria can develop itself to resist antibiotics, therefore, they misunderstand that antibiotics can relieve pain, reduce fever which can lead to misuse of antibiotics. Drug resistance related knowledge and antibiotic misuse affect the development of drug-resistant strains. There are more than 38,000 deaths each year in Thailand which cost economical loss which accounted for 0.6% of gross domestic product. Objectives: The purpose of this study was to assess drug resistance related knowledge, attitude toward drug resistance prevention, and drug resistance preventive behaviors among Thai people. Materials and Methods: An online cross-sectional survey was conducted among 1123 Thai people who could access the internet. Drug resistance related knowledge, attitude, and behavior toward drug resistance prevention was assessed. Differences between outcomes and sociodemographic were analyzed through independent t-test, ANOVA.A generalized linear model was calculated to determine the predictive variables of preventive behaviors. Results: Participants revealed moderate knowledge about drug resistance, correctly answering 9.86 (SD = 1.65) questions in a total of 15 and favorable attitudes toward preventive behaviors (M = 24.78, SD = 3.25). Participants reported on average 45.92 (SD = 7.25) of 12 behaviors in terms of always engaging in prevention, which was considered to be moderate. Females presented a higher level of knowledge, more positive attitude, and engaged in more preventive behaviors than males. Age, educational attainment, level of income, and knowledge about drug resistance had a negative correlation with preventive behavior toward drug resistance (r = –0.109**, r = –0.081**, r = –0.197**, and –0.111**, P< 0.01). Having a positive attitude toward preventive behavior of drug resistance predicted the adoption of those preventive behaviors (Exp (β) = 0.83, 95% CI: 0.046–0.325, P < 0.01). Conclusion: Participants had a moderate level of knowledge on drug resistance, favorable attitude toward drug resistance prevention, and moderate level of preventive behaviors. Participants who had a busy lifestyle were more likely to compromise preventive behavior toward drug resistance, mostly in the 30–50 age group, even though their level of attitude toward prevention was at a good level. From the study, it is clear that prioritizing public knowledge on drug resistance is strongly and urgently advised to heighten attitudes toward drug resistance prevention to improve drug preventive behavior. More importantly, long-term systematic interventions and solutions should be considered, such as integrating, improving, and stressing the ed
背景:很多泰国人对抗生素存在误解,比如认为抗生素是一种消炎药。这导致了一种误解,认为使用这种药物会使现有的疾病愈合得更快,因为这种药物会治疗或治愈炎症。许多人不知道细菌本身可以产生抗药性,因此,他们误解抗生素可以缓解疼痛,退烧,这可能导致滥用抗生素。耐药相关知识和抗生素滥用影响耐药菌株的发展。泰国每年有超过38,000人死亡,造成的经济损失占国内生产总值的0.6%。目的:了解泰国人群耐药相关知识、耐药预防态度及耐药预防行为。材料与方法:对1123名能上网的泰国人进行在线横断面调查。评估耐药相关知识、耐药预防态度和行为。结果与社会人口学差异通过独立t检验、方差分析进行分析。计算广义线性模型,确定预防行为的预测变量。结果:受访人员对耐药知识的了解程度一般,正确回答问题9.86个(SD = 1.65),对耐药预防行为态度良好(M = 24.78, SD = 3.25)。参与者报告的12种行为中,平均有45.92 (SD = 7.25)的人总是参与预防,被认为是中度的。女性的知识水平、积极态度和预防行为均高于男性。年龄、文化程度、收入水平、耐药知识与耐药预防行为呈负相关(r = - 0.109**、r = - 0.081**、r = - 0.197**、- 0.111**,P< 0.01)。对耐药预防行为持积极态度能预测耐药预防行为的采取(Exp (β) = 0.83, 95% CI: 0.046 ~ 0.325, P < 0.01)。结论:受访人员耐药知识水平中等,对耐药预防态度良好,预防行为水平中等。生活忙碌的参与者更有可能在耐药性预防行为上妥协,主要集中在30 - 50岁年龄组,尽管他们对预防的态度水平处于良好水平。从这项研究中可以清楚地看出,强烈而迫切地建议优先考虑公众对耐药性的认识,以提高对耐药性预防的态度,以改善药物预防行为。更重要的是,应考虑长期系统的干预措施和解决方案,如整合、改进和强调对耐药性问题的教育。
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引用次数: 0
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International Journal of Medical Science and Public Health
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