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A cross-sectional study on the compliance to antihypertensive drugs in a rural area 农村地区降压药依从性的横断面研究
Pub Date : 2020-01-01 DOI: 10.5455/ijmsph.2020.06098202025072020
S. Pandian, M Vijaykarthikeyan, R. Umadevi
Background: The burden of the non-communicable diseases (NCDs) is increasing over the years. Worldwide, the leading cause of morbidity and mortality has been due to NCDs. Although NCDs are multifactorial, hypertension plays a major role as a risk factor. Lack of treatment adherence can lead to negative health consequences. Objectives: The objectives of the study were as follows: (1) To assess patients’ compliance to antihypertensive drugs; (2) to evaluate association between treatment compliance and sociodemographic determinants; and (3) to find out the factors responsible for non-adherence. Materials and Methods: This study was carried among 350 hypertensive patients in the rural field practice area of a medical college using simple random sampling method. The study population consists of hypertensive patients belonging to 20–60 years of age. A pretested structured questionnaire containing Morisky’s scale was used to assess patient’s adherence. Data analysis was done using SPSS (Version 22). Results: Nearly 53.7% of the study participants were female. The prevalence of treatment compliance was estimated to be 24.6%. Statistically significant association was observed between age, education, and socioeconomic status with adherence to hypertensive medications (P < 0.05). Many reasons were identified for non-adherence and they include cost of treatment (21.4 %), side effects (27.5%), alternative treatment (16%), lack of knowledge (32.8%), and multiple drugs (25%). Conclusion: The prevalence of 23.6% of patient’s being adherent to hypertensive medications was observed among the study population. It is necessary to strengthen treatment adherence by various health education campaigns and implementing various health programs.
背景:近年来,非传染性疾病(NCDs)的负担不断增加。在世界范围内,发病率和死亡率的主要原因是非传染性疾病。虽然非传染性疾病是多因素的,但高血压作为一个危险因素起着主要作用。缺乏治疗依从性可导致负面的健康后果。目的:本研究的目的如下:(1)评估患者对降压药物的依从性;(2)评估治疗依从性与社会人口统计学决定因素之间的关系;(3)找出导致不依从的因素。材料与方法:采用简单随机抽样的方法对某医学院农村实习区350例高血压患者进行研究。研究人群为20 - 60岁的高血压患者。采用预先测试的结构化问卷(包含Morisky量表)来评估患者的依从性。使用SPSS (Version 22)进行数据分析。结果:近53.7%的研究参与者为女性。治疗依从率估计为24.6%。年龄、受教育程度和社会经济地位与高血压药物依从性有统计学意义(P < 0.05)。不坚持治疗的原因有很多,包括治疗费用(21.4%)、副作用(27.5%)、替代治疗(16%)、缺乏相关知识(32.8%)和多种药物(25%)。结论:研究人群高血压药物依从率为23.6%。有必要通过各种健康教育活动和实施各种健康方案来加强治疗依从性。
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引用次数: 0
A descriptive study to assess the awareness of communication and social mobilization activities for tuberculosis control among households in rural area of Shivamogga, Karnataka 一项描述性研究,旨在评估卡纳塔克邦Shivamogga农村地区家庭对结核病控制的沟通和社会动员活动的认识
Pub Date : 2020-01-01 DOI: 10.5455/ijmsph.2020.0823708112019
C. Nandini, K. Nagendra
Background: Advocacy, communication, and social mobilization addresses four key challenges such as improving case detection and treatment adherence, reducing stigma and discrimination, empowering tuberculosis (TB) patients, and mobilizing the resources and political commitment required to combat TB. A multipronged approach included activities to disseminate information through information, education, and communication materials, and simultaneously initiating community-based activities by actively involving and sensitizing communities on TB. Objectives: The objectives of this study were as follows: (1) To assess the awareness of communication and social mobilization activities among households in rural field practice area of Shimoga Institute of Medical Sciences, Shivamogga and (2) to know the preferred sources of communication and social mobilization activities among households in rural field practice area of Shimoga Institute of Medical Sciences, Shivamogga. Materials and Methods: A cross-sectional community-based study was conducted among households in rural field practice area of Shimoga Institute of Medical Sciences, Shivamogga. After taking approval from the Institutional Ethical Committee, data were collected by doing house-to-house visits until all the houses in that particular village were covered. After taking informed consent, every household willing to be a part of the study was subjected to personal interviews using a semi-structured and pre-tested questionnaire, which was initially developed in English, and all the questions were translated into local language Kannada for the target population. Statistical analysis was done using SPSS software. Results: Of 100 households covered, females (74%) were more compared to males (26%), and among media information sources of TB; unaware (43%), television (TV) (26%), posters in health center (5%), and among community information source of TB; and unaware (34%), health-care provider (36%), and peers (11%). Most of them preferred TV and health-care providers as the priority to disseminate health education. Conclusion: The awareness of communication and social mobilization activities is very poor among rural people, which requires effective use of media information sources such as TV, radio, and digital innovations to convey the information with high priority to community participation in all social mobilization activities.
背景:宣传、沟通和社会动员可解决四项关键挑战,如改善病例发现和治疗依从性、减少污名和歧视、增强结核病患者权能、调动防治结核病所需的资源和政治承诺。多管齐下的方法包括通过信息、教育和宣传材料传播信息,同时通过积极让社区参与并提高社区对结核病的认识,开展以社区为基础的活动。目的:本研究的目的是:(1)了解下野村医学研究所农村实地实习区家庭对沟通和社会动员活动的认知情况;(2)了解下野村医学研究所农村实地实习区家庭对沟通和社会动员活动的偏好来源。材料与方法:采用基于社区的横断面研究方法,对下野町医学研究所农村田间实习区住户进行调查。在获得机构伦理委员会的批准后,通过挨家挨户的访问收集数据,直到该特定村庄的所有房屋都被覆盖。在获得知情同意后,每个愿意成为研究一部分的家庭都接受了半结构化和预测试问卷的个人访谈,该问卷最初是用英语开发的,所有问题都被翻译成目标人群的当地语言卡纳达语。采用SPSS软件进行统计分析。结果:在所覆盖的100个家庭中,女性(74%)多于男性(26%),并且在结核病的媒体信息来源中;不知情(43%)、电视(TV)(26%)、卫生中心海报(5%)和社区结核病信息源;不知情(34%)、医疗保健提供者(36%)和同伴(11%)。他们中的大多数人首选电视和保健提供者作为传播健康教育的重点。结论:农村人群对传播和社会动员活动的意识很差,需要有效利用电视、广播、数字创新等媒体信息来源,将信息传递出去,并将社区参与到所有社会动员活动中。
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引用次数: 0
Assessment of well-being and coping abilities among medical and paramedical trainees, in a Government Medical College, West Uttar Pradesh, India 在印度西北方邦一所政府医学院对医疗和辅助医疗受训人员的福祉和应对能力进行评估
Pub Date : 2020-01-01 DOI: 10.5455/ijmsph.2020.02024202008022020
R. Kumar, Anita Maurya, D. Singh, P. Dudeja
Background: High levels of stress and psychological morbidity occur in health-care professional students. Objective: The objective of this study was to estimate psychological well-being, perceived stress level, and coping abilities among medical and paramedical students. Materials and Methods: A cross-sectional analytical study carried out in a tertiary care hospital, West Uttar Pradesh, India. The total study period was from September 2019 to November 2019 with a sample of 145 medical students aged 17–25 years and 81 paramedical students aged 19–33 years. Ethical clearance was obtained from the College Ethical Committee. We used self-administered, three different types of validated tools for data collection. Data were analyzed using SPSS Version 20. Results: The median age of paramedical and medical trainees was 22 and 21 years, respectively. Family history of mental illness was 21% and 5.5%, respectively. On general health questionnaire-12 scale, 9% of paramedical trainees reported evidence of distress and 91% of severe problem and psychological distress while 19% of medical trainees having evidence of distress and 81% of severe problem and psychological distress. On perceived stress scale-10 (PSS-10) scale, 15% of paramedical trainees reported average level, 27% moderate level, and 55% high level of perceived stress while 2% of medical trainees having average, 19% moderate level, and 79% high level of perceived stress, respectively. The difference in mean score on PSS-10 and Brief COPE scale between paramedics and medical trainees group was found statistically significant (P < 0.05). Conclusion: We concluded the higher level of severe problem and psychological distress in the paramedical and high level of perceived stress in medical trainees. Paramedical trainees practice a better coping mechanism than medical trainees.
背景:高水平的压力和心理疾病发生在卫生保健专业的学生中。目的:本研究的目的是评估医学生和准医学生的心理健康状况、感知压力水平和应对能力。材料和方法:在印度西北方邦的一家三级保健医院进行的横断面分析研究。总研究期为2019年9月至2019年11月,样本为145名17 - 25岁的医学生和81名19 - 33岁的医学生。获得了学院伦理委员会的伦理许可。我们使用自我管理的,三种不同类型的验证工具来收集数据。数据分析使用SPSS Version 20。结果:辅助医师和医学研修生的中位年龄分别为22岁和21岁。精神疾病家族史分别为21%和5.5%。在一般健康问卷-12量表上,9%的辅助医务学员报告有痛苦的证据,91%的人报告有严重问题和心理困扰,而19%的医务学员报告有痛苦的证据,81%的人报告有严重问题和心理困扰。在压力感知量表-10 (PSS-10)中,15%的辅助医疗学员的压力感知水平为平均水平,27%为中等水平,55%为高水平,2%的医疗学员的压力感知水平为平均水平,19%为中等水平,79%为高水平。护理人员组与实习医师组在PSS-10和Brief COPE量表上的平均得分差异有统计学意义(P < 0.05)。结论:医务辅助人员的严重问题和心理困扰水平较高,医学实习生的感知压力水平较高。辅助医疗培训生的应对机制优于医学培训生。
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引用次数: 3
The association between the duration of using ocular prosthesis and upper and lower conjunctival fornix depth 眼假体使用时间与上、下结膜穹窿深度的关系
Pub Date : 2020-01-01 DOI: 10.5455/ijmsph.2020.08133202018082020
Tari Adrian, R. R. Lubis, A. Arma
Background: Ocular prosthesis is needed to replace the content of eyeball lost due to several factors. Adequate retention of ocular prosthesis requires an adequate upper and lower conjunctival fornix depth. Objectives: The objectives of the study were to evaluate the association between the duration of using ocular prosthesis and upper and lower conjunctival fornix depth. Materials and Methods: A case–control study was conducted in 30 anophthalmic socket patients aged 22–77 that using ocular prosthesis more than 6 months. The contralateral eye with healthy socket was chosen as a control group. Upper and lower conjunctival fornix depth were measure using fornicometer. We design a fornix depth measurer for objective measurement of upper and lower conjunctival fornix depth. Results: From 30 anophthalmic socket patients, males were about 14 times more often than female, with the average age that was 51. The mean upper conjunctival fornix depth in males was 10.8 ± 0.6 and lower conjunctival fornix depth was 6.2 ± 0.8. The mean upper conjunctival fornix depth in females was 10.80± 0.6 and lower conjunctival fornix depth was 5.5 ± 0.7. There is medium relationship between upper conjunctival fornix depth and the duration of using prosthesis (cc = −0.435; P = 0.016) and there is high relationship between lower conjunctival fornix depth and the duration of using prosthesis (cc = −0.551; P = 0.002). Conclusions: There was a significant association between the duration of using ocular prosthesis and upper and lower conjunctival fornix depth.
背景:由于多种因素导致眼球内容物丢失,需要人工眼。眼假体的充分保留需要足够的上、下结膜穹窿深度。目的:本研究的目的是评估眼假体使用时间与上、下结膜穹窿深度之间的关系。材料与方法:对30例22 ~ 77岁无眼窝且使用人工眼6个月以上的患者进行病例对照研究。选取正常眼窝的对侧眼作为对照组。采用穹窿计测量上、下结膜穹窿深度。我们设计了一种穹窿深度测量仪,用于客观测量上、下结膜穹窿深度。结果:30例眼窝无闭患者中,男性约为女性的14倍,平均年龄51岁。男性结膜上穹窿平均深度为10.8±0.6,下结膜穹窿平均深度为6.2±0.8。女性上结膜穹窿平均深度为10.80±0.6,下结膜穹窿平均深度为5.5±0.7。上结膜穹窿深度与假体使用时间呈中等相关性(cc =−0.435;P = 0.016),下结膜穹窿深度与假体使用时间高度相关(cc =−0.551;P = 0.002)。结论:眼假体使用时间与上、下结膜穹窿深度有显著相关性。
{"title":"The association between the duration of using ocular prosthesis and upper and lower conjunctival fornix depth","authors":"Tari Adrian, R. R. Lubis, A. Arma","doi":"10.5455/ijmsph.2020.08133202018082020","DOIUrl":"https://doi.org/10.5455/ijmsph.2020.08133202018082020","url":null,"abstract":"Background: Ocular prosthesis is needed to replace the content of eyeball lost due to several factors. Adequate retention of ocular prosthesis requires an adequate upper and lower conjunctival fornix depth. Objectives: The objectives of the study were to evaluate the association between the duration of using ocular prosthesis and upper and lower conjunctival fornix depth. Materials and Methods: A case–control study was conducted in 30 anophthalmic socket patients aged 22–77 that using ocular prosthesis more than 6 months. The contralateral eye with healthy socket was chosen as a control group. Upper and lower conjunctival fornix depth were measure using fornicometer. We design a fornix depth measurer for objective measurement of upper and lower conjunctival fornix depth. Results: From 30 anophthalmic socket patients, males were about 14 times more often than female, with the average age that was 51. The mean upper conjunctival fornix depth in males was 10.8 ± 0.6 and lower conjunctival fornix depth was 6.2 ± 0.8. The mean upper conjunctival fornix depth in females was 10.80± 0.6 and lower conjunctival fornix depth was 5.5 ± 0.7. There is medium relationship between upper conjunctival fornix depth and the duration of using prosthesis (cc = −0.435; P = 0.016) and there is high relationship between lower conjunctival fornix depth and the duration of using prosthesis (cc = −0.551; P = 0.002). Conclusions: There was a significant association between the duration of using ocular prosthesis and upper and lower conjunctival fornix depth.","PeriodicalId":14153,"journal":{"name":"International Journal of Medical Science and Public Health","volume":"49 1","pages":"444-448"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91067083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Visual impairment and blindness among elderly in rural area of North Karnataka - A cross-sectional study 北卡纳塔克邦农村地区老年人视力障碍和失明的横断面研究
Pub Date : 2020-01-01 DOI: 10.5455/ijmsph.2020.06101202003072020
Preet P. Khona, G. Sujatha
Background: Loss of sight of a person should not remain just a statistic but a personal tragedy, not only for the individual concerned but for all of us who claim to be concerned. With the introduction of universal eye health: A global action plan 2014–2019, dealing with a reduction in avoidable blindness across the world, this study would help in enlightening the present scenario in this region. Objective: The objective of the study was to know the prevalence of visual impairment and blindness among elderly in a rural area. Materials and Methods: All individuals aged 60 years and above residing in the area covered under Vantamuri Primary Health Centre (PHC), Belagavi, were selected for the study. A sample size of 620 was calculated and obtained by population proportionate sampling from five subcenters under Vantamuri PHC. Sociodemographic data were collected from the study subject with the help of pre-designed and pre-tested questionnaire and detailed ocular examination was carried out. Ethical clearance was obtained from the Institutional Ethics Committee. Results: The prevalence of visual impairment and blindness in our study was 28.07% and 2.90%, respectively. Female constituted more than half (61.11%) of blind individuals, whereas male (51.39%) dominated visual impairment. Cataract was the most common cause of visual impairment and blindness. Conclusion: Blindness was more common among elderly female compared to male. Cataract being the most common cause for visual impairment, it can be prevented by more coverage and better health care services in the rural area.
背景:一个人的失明不应该仅仅是一个统计数字,而应该是一个个人的悲剧,不仅对于相关的个人,而且对于我们所有声称关心的人。随着《全民眼睛健康:2014 - 2019年全球行动计划》的推出,这项研究将有助于启发该地区目前的情况。该计划旨在减少世界各地可避免失明的人数。目的:了解农村老年人视力障碍和失明的流行情况。材料和方法:所有居住在Belagavi Vantamuri初级保健中心(PHC)覆盖地区的60岁及以上的个人都被选为研究对象。通过从万塔穆里初级保健中心的五个亚中心按人口比例抽样,计算和获得了620个样本量。通过预先设计和预先测试的问卷收集研究对象的社会人口学数据,并进行详细的眼部检查。获得了机构伦理委员会的伦理许可。结果:本研究中视力障碍和失明的患病率分别为28.07%和2.90%。女性占盲人总数的一半以上(61.11%),男性占51.39%。白内障是视力受损和失明的最常见原因。结论:老年女性失明发生率高于老年男性。白内障是造成视力损害的最常见原因,在农村地区扩大覆盖面和提供更好的保健服务可以预防白内障。
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引用次数: 0
Part-time work among nursing students of Sohag University, Egypt 埃及Sohag大学护理专业学生兼职工作
Pub Date : 2020-01-01 DOI: 10.5455/ijmsph.2020.0203115022020
R. Ali, Eman Roshdy
Background: The last years spectacle an increase in the number of full-time nursing students joining in paid work, and the number of working hours during the study that may affect students health, the causes for the increasing numbers of full-time students in paid work are usually approved to be driven from increasing the expenses related to study and the fluctuations in the funding system. Objective: The objective of the study was to evaluate the prevalence, magnitude, and nature of part-time work among undergraduate nursing students of Faculty of Nursing and students of Nursing Institute at Sohag University. Materials and Methods: This is a cross-sectional study that was performed through the academic year 2018–2019. Results: The prevalence of part-time work among the studied nursing students was 41.3%, the associated factors which found to be significant in contributing for working among students are being male (P < 0.001; adjusted odds ratio [AOR] 3.1; 95% [CI: 2.19–4.7]), and father having basic education only (P = 0.02; AOR 2.3; 95% [CI: 1.39–2.7]) was independently associated with students’ employment. About 56.9% of the participants work for financial support and 32.4% work to gain experience; exposure to physical hazards and biological hazards was the utmost common health hazards reported by working nursing students, musculoskeletal complaints were the most recurrent occupational health effects (80%). Conclusion: Working among nursing students becomes a common phenomenon that has a positive and negative impact, it leads to gaining clinical experience among students through working but at the same time, they are at a risk of exposure to physical, biological, and mechanical hazards.
背景:近年来,全日制护生从事带薪工作的人数有所增加,而学习期间的工作时数可能会影响学生的健康,全日制护生从事带薪工作的人数增加的原因通常被认为是与学习费用增加和资助制度的波动有关。目的:本研究的目的是评估苏海大学护理学院和护理学院护理本科生兼职工作的发生率、程度和性质。材料和方法:这是一项横断面研究,在2018 - 2019学年进行。结果:护生从事兼职工作的比例为41.3%,对学生从事兼职工作有显著影响的相关因素为男性(P < 0.001;调整优势比[AOR] 3.1;95% [CI: 2.19—4.7]),父亲仅受过基础教育(P = 0.02;优势比2.3;95% [CI: 1.39—2.7])与学生就业独立相关。约56.9%的人工作是为了经济支持,32.4%的人工作是为了积累经验;接触物理危害和生物危害是在职护理学生报告的最常见的健康危害,肌肉骨骼疾病是最常见的职业健康影响(80%)。结论:护生打工已成为一种普遍现象,既有积极的影响,也有消极的影响,学生通过打工获得临床经验的同时,也面临着接触物理、生物和机械危害的风险。
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引用次数: 0
Atypical cause of fever in advanced pregnancy 妊娠晚期发热的不典型原因
Pub Date : 2020-01-01 DOI: 10.5455/ijmsph.2020.1030821112019
Suman Panda, B. Satyanarayan, H. Sinha, S. Trivedi, S. K. Prasad
Although miliary tuberculosis (TB) is uncommon in pregnancy, it is difficult to diagnose when present and is often associated with a maternal history of intravenous drug abuse, malignancy, alcoholism, or human immunodeficiency virus (HIV) infection. TB in pregnancy can present with non-pulmonary symptoms, making the diagnosis and treatment challenging. We report a case of military TB in a lady with advanced pregnancy who presented with fever and cough without any history of exposure to TB patient. There was no history of alcoholism, intravenous drug abuse, or any other risk factors. Sputum for acid-fast bacilli stains and HIV screening were negative. The patient was started on anti-TB treatment after blood investigations ruled out other causes of fever and chest radiograph was suggestive of miliary TB. Confirming the diagnosis of miliary TB is an arduous process requiring a high index of suspicion. During pregnancy, histopathologic examination of tissue biopsy and GeneXpert may facilitate making an early diagnosis of extrapulmonary TB.
虽然军旅性肺结核(TB)在妊娠中并不常见,但当出现时很难诊断,并且通常与母体静脉药物滥用、恶性肿瘤、酒精中毒或人类免疫缺陷病毒(HIV)感染史有关。妊娠期结核病可出现非肺部症状,使诊断和治疗具有挑战性。我们报告一例军队结核在一位女士与晚期妊娠谁提出发烧和咳嗽没有任何历史暴露于结核病患者。没有酗酒史,静脉注射药物滥用史,或任何其他危险因素。痰液抗酸杆菌染色及HIV筛查均为阴性。在血液检查排除其他发热原因后,患者开始接受抗结核治疗,胸片显示为军旅性结核。确认军队结核病的诊断是一个艰巨的过程,需要高度怀疑。在怀孕期间,组织活检和GeneXpert的组织病理学检查可能有助于早期诊断肺外结核。
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引用次数: 0
Pattern of care and epidemiology of brain metastasis over past 10 years: A retrospective study from tertiary cancer center 近10年来脑转移的护理模式和流行病学:来自三级肿瘤中心的回顾性研究
Pub Date : 2020-01-01 DOI: 10.5455/ijmsph.2020.1131621112019
S. Dutta, Anjan Bera, S. Mandal, Debojyoti Manna, Aparajita Sadhya, Linkon Biswas, J. Saha
Background: In adults most common intracranial malignant lesion is brain metastasis, far outnumbering primary brain tumor. The most common primary site is lung cancer (18–64%), followed by breast (25–21%), malignant melanoma (4–16%), and colorectal cancer (2–12%). It is hypothesized that the incidence of brain metastasis might be increasing, as a result of increasing survival from recent advance in cancer treatment, more frequent brain screening for specific primary malignancy that known to have a higher prediction for brain metastasis and greater availability and use of magnetic resonance imaging (MRI) of brain. In clinical oncology, understanding brain metastasis is important, because it has profound effect on length of survival, quality of life, and in one-third to one-half of affected patients, they represent the direct cause of death despite current improvement in therapeutic approach. Epidemiological data of brain metastasis are lacking in India. Objectives: Aims of our retrospective analysis are to study epidemiology and pattern of care of brain metastasis over last one decade in Nil Ratan Sircar Medical College and Hospital, Kolkata. Materials and Methods: Between 2006 and December 2017, a total of 710 patients of brain metastasis treated in our department with palliative intent were analyzed retrospectively. New-onset neurological symptoms in a known case of cancer we always presumed that, symptoms were due to brain metastasis until proven otherwise. Hence, all patients presenting with acute neurological signs and symptoms underwent through clinical examination, contrast-enhanced (CE) computed tomography brain, and/or CEMRI of brain. Epidemiology, pattern of care, and outcome in the form of overall survival (OS) and disease-free survival were determined. Results: Fifty-seven percent patients were male. The median age was 62 years at the time of diagnosis. Lung carcinoma was most common primary site seen in 52% patients, followed by carcinoma breast second most common primary site, seen in 32% patients. Headache (73%) and motor weakness were most common presenting symptoms. Supratentorial location most common site, out of which parietal region is most common. The only small number of patients was offered best supportive care alone whereas majority of the patients were considered fit for palliative therapy. Treatment consisted of metastasectomy when possible and palliative whole-brain radiotherapy (WBRT) alone or followed by systemic therapy. Optimal supportive care in addition to chemotherapy or radiotherapy is given to all patients. A total of 254 patients were given blood product, erythropoietin, granulocyte-colony-stimulating factor following chemotherapy. Hospitalization required in 71% patients and tumor-related problem was most common cause (46%). Remaining patients were hospitalized for delivery WBRT or CCT. The median OS is 9 months. Patients with younger age and breast primary associated with better prognosis than lung p
背景:在成人中最常见的颅内恶性病变是脑转移,远远超过原发脑肿瘤。最常见的原发部位是肺癌(18 - 64%),其次是乳腺癌(25 - 21%)、恶性黑色素瘤(4 - 16%)和结直肠癌(2 - 12%)。据推测,脑转移的发生率可能正在增加,因为癌症治疗的最新进展提高了生存率,对特定原发性恶性肿瘤进行更频繁的脑筛查,已知对脑转移有更高的预测,以及更广泛的脑磁共振成像(MRI)的使用。在临床肿瘤学中,了解脑转移是很重要的,因为它对生存时间和生活质量有着深远的影响,尽管目前的治疗方法有所改善,但在三分之一到一半的受影响患者中,脑转移是导致死亡的直接原因。印度缺乏脑转移的流行病学资料。目的:回顾性分析加尔各答尼尔拉坦锡尔卡医学院和医院近十年来脑转移的流行病学和护理模式。材料与方法:回顾性分析2006年至2017年12月我科以姑息治疗为目的收治的710例脑转移患者。在一个已知的癌症病例中出现了新发的神经系统症状,我们一直认为这些症状是由于脑转移引起的,直到事实证明并非如此。因此,所有出现急性神经系统体征和症状的患者均通过临床检查、脑ct增强(CE)和/或脑CEMRI。确定流行病学、护理模式以及总生存期(OS)和无病生存期的结果。结果:57%的患者为男性。确诊时的中位年龄为62岁。肺癌是最常见的原发部位,占52%,其次是乳腺癌,占32%。头痛(73%)和运动无力是最常见的症状。幕上部位是最常见的部位,其中顶叶区域最常见。只有少数患者获得了最好的支持性治疗,而大多数患者被认为适合姑息治疗。治疗包括在可能的情况下进行转移切除术和姑息性全脑放疗(WBRT)或随后进行全身治疗。除化疗或放疗外,对所有患者给予最佳的支持治疗。254例患者化疗后给予血制品、促红细胞生成素、粒细胞集落刺激因子。71%的患者需要住院治疗,肿瘤相关问题是最常见的原因(46%)。其余患者住院分娩WBRT或CCT。中位生存期为9个月。年龄较小且乳房原发的患者预后较肺部原发患者好。结论:男性肺癌和女性乳腺癌是脑转移最常见的病因。由于姑息治疗的进步,脑转移患者的预后得到改善,脑转移患者受益于姑息放疗和化疗,并且可以方便地在门诊进行姑息治疗。
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引用次数: 1
Role of polymerase chain reaction of ascitic fluid and its correlation with adenosine deaminase levels in the diagnosis of abdominal tuberculosis 腹水聚合酶链反应及其与腺苷脱氨酶水平的相关性在腹部结核诊断中的作用
Pub Date : 2020-01-01 DOI: 10.5455/ijmsph.2020.12343201930062020
B. Singh, Kirti Singh, R. Khanna, R. Meena
Background: It is still difficult to diagnose tuberculosis as a source of abdominal pain. Due to the lack of non-invasive diagnostic testing, the diagnosis remains a problem. Determining the role of polymerase chain reaction (PCR) in ascitic fluid in the diagnosis of abdominal tuberculosis, we can conclude whether it is sensitive/specific or not and further its use in the diagnosis of abdominal tuberculosis. Objective: The objective of the study was to determine the role of PCR in ascitic fluid in the diagnosis of abdominal tuberculosis and also to correlate the ADA levels of ascitic fluid with the PCR report. Materials and Methods: This prospective comparative study includes 41 clinically suspected abdominal tuberculosis patients (age range 15–65 years) over a period of 2 years. A detailed history, clinical evaluation, and relevant investigations, including radiology, were done in all patients. Bacteriological or histological approaches had to support the diagnosis of abdominal tuberculosis, and PCR was also tested for Mycobacterium tuberculosis in ascitic fluid. Results: The mean age of patients was 31.71±12.32 years with male:female ratio was 1.4:1. PCR was positive in 24 (58.8%) cases. A receiver operating characteristic curve showed that a cutoff value of 35.3 IU/L (AUC 0.998, P < 0.001) for the ADA level produced the best results as a diagnostic test for abdominal tuberculosis, yielding the following parameter values: Sensitivity 100%, specificity 94.1%, positive predictive value 96%, negative predictive value 100%, and diagnostic accuracy 97.56%. ADA values were significantly elevated during abdominal tuberculosis, indicating that ADA can still be a valuable diagnostic tool. Conclusion: Our findings indicate that ascitic fluid PCR is a safe tool for diagnosing it and should be tried at least before surgical intervention.
背景:诊断结核是否为腹痛的原因仍然很困难。由于缺乏无创诊断测试,诊断仍然是一个问题。测定腹水聚合酶链反应(PCR)在诊断腹水结核中的作用,可以判断其是否敏感/特异性,并进一步应用于腹水结核的诊断。目的:本研究的目的是确定腹水PCR在腹结核诊断中的作用,并将腹水ADA水平与PCR报告联系起来。材料与方法:本前瞻性比较研究纳入41例临床疑似腹部结核患者(年龄15 ~ 65岁),为期2年。对所有患者进行详细的病史、临床评估和相关调查,包括影像学检查。细菌学或组织学方法必须支持腹部结核的诊断,PCR也用于腹水结核分枝杆菌的检测。结果:患者平均年龄为31.71±12.32岁,男女比例为1.4:1。PCR阳性24例(58.8%)。受试者工作特征曲线显示,ADA水平的临界值为35.3 IU/L (AUC 0.998, P < 0.001),作为腹结核的诊断指标效果最佳,其参数值为:敏感性100%,特异性94.1%,阳性预测值96%,阴性预测值100%,诊断准确率97.56%。腹结核期间ADA值显著升高,表明ADA仍可作为一种有价值的诊断工具。结论:腹水PCR是一种安全的诊断手段,至少应在手术前尝试。
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引用次数: 0
Assessment of knowledge and practice towards COVID-19 amid inhabitants of Karnataka 卡纳塔克邦居民COVID-19知识和实践评估
Pub Date : 2020-01-01 DOI: 10.5455/ijmsph.2020.05058202062042020
S ArpithaV, P. Patil, N. Pradeep
Background: COVID-19 outbreak has been declared as pandemic by WHO on March 11, 2020. Globally more than 16 lakh cases have been reported, affecting nearly 195 nations till April 12th 2020. Health authorities have initiated measures to create awareness and to control the spread. Objectives: To assess the Knowledge and practices of general public towards COVID-19. Materials and Methods: A cross sectional study was carried out among general public residing in Karnataka. Online questioner was prepared and circulated in social media and responses were collected during March 2020. Data was analysed using SPSS 23.0, descriptive statistics were calculated. Knowledge scores and practices with socio-demographic profile were done using Independent t test, one-way ANOVA and Chi-square test. Results: A total of 1048 responses were received. Majority were males (61.3%), married (57.4%), of age 20–40 years (79.4%) and held a bachelor degree (53.1%). The mean knowledge score for COVID 19 was 11.7 ± 2.07. There was a statistically significant difference of knowledge score among various socio-demographic variable like age (P = 0.009), gender (P = 0.001), educational status (P = 0.00) and marital status (P = 0.00). Majority of the study participants preferred consulting a doctor 964 (91.84%) when they have symptoms like fever and cough. 68 (6.4%) of the study participants had been to crowded places in recent times. 974 (92.9%) and 843 (80.5%) update their knowledge and prefer wearing mask outside the home respectively. Conclusion: More than three-fourth of the participants had adequate knowledge and around 90% of the participants had satisfactory practices towards COVID-19.
背景:2020年3月11日,世卫组织宣布新冠肺炎疫情为大流行。截至2020年4月12日,全球已报告了160多万例病例,影响了近195个国家。卫生当局已采取措施提高认识并控制传播。目的:了解公众对COVID-19的知识和做法。材料与方法:对居住在卡纳塔克邦的普通民众进行了横断面研究。在2020年3月期间,准备了在线问题并在社交媒体上传播,并收集了回复。数据分析采用SPSS 23.0,进行描述性统计。知识得分和实践与社会人口学概况采用独立t检验、单因素方差分析和卡方检验。结果:共收到1048份回复。大多数为男性(61.3%),已婚(57.4%),年龄20 - 40岁(79.4%),本科学历(53.1%)。新冠肺炎知识平均得分为11.7±2.07分。年龄(P = 0.009)、性别(P = 0.001)、学历(P = 0.00)、婚姻状况(P = 0.00)等社会人口学变量的知识得分差异有统计学意义。大多数研究参与者(91.84%)在出现发烧和咳嗽等症状时更倾向于咨询医生。68名(6.4%)研究参与者最近去过拥挤的地方。974名(92.9%)和843名(80.5%)受访者表示会更新知识,并喜欢在户外佩戴口罩。结论:超过四分之三的参与者对COVID-19有足够的知识,约90%的参与者对COVID-19有满意的做法。
{"title":"Assessment of knowledge and practice towards COVID-19 amid inhabitants of Karnataka","authors":"S ArpithaV, P. Patil, N. Pradeep","doi":"10.5455/ijmsph.2020.05058202062042020","DOIUrl":"https://doi.org/10.5455/ijmsph.2020.05058202062042020","url":null,"abstract":"Background: COVID-19 outbreak has been declared as pandemic by WHO on March 11, 2020. Globally more than 16 lakh cases have been reported, affecting nearly 195 nations till April 12th 2020. Health authorities have initiated measures to create awareness and to control the spread. Objectives: To assess the Knowledge and practices of general public towards COVID-19. Materials and Methods: A cross sectional study was carried out among general public residing in Karnataka. Online questioner was prepared and circulated in social media and responses were collected during March 2020. Data was analysed using SPSS 23.0, descriptive statistics were calculated. Knowledge scores and practices with socio-demographic profile were done using Independent t test, one-way ANOVA and Chi-square test. Results: A total of 1048 responses were received. Majority were males (61.3%), married (57.4%), of age 20–40 years (79.4%) and held a bachelor degree (53.1%). The mean knowledge score for COVID 19 was 11.7 ± 2.07. There was a statistically significant difference of knowledge score among various socio-demographic variable like age (P = 0.009), gender (P = 0.001), educational status (P = 0.00) and marital status (P = 0.00). Majority of the study participants preferred consulting a doctor 964 (91.84%) when they have symptoms like fever and cough. 68 (6.4%) of the study participants had been to crowded places in recent times. 974 (92.9%) and 843 (80.5%) update their knowledge and prefer wearing mask outside the home respectively. Conclusion: More than three-fourth of the participants had adequate knowledge and around 90% of the participants had satisfactory practices towards COVID-19.","PeriodicalId":14153,"journal":{"name":"International Journal of Medical Science and Public Health","volume":"7 1","pages":"300-304"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84969452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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International Journal of Medical Science and Public Health
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