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Incidence of Diabetes Mellitus Type II and Pre-Diabetes among Hand Nerves Entrapment Neuropathy Patients: Epidemiological Study 手神经卡压性神经病患者糖尿病II型和糖尿病前期的发病率:流行病学研究
Pub Date : 2021-01-01 DOI: 10.35248/2329-9096.21.9.604
Naglaa A. Hussein, M. Bartels, Mark G. Thomas, David Z. Prince
Objective: Measure the incidence of Diabetes Mellitus (DM)/pre-diabetes among patients with hand nerves entrapment syndromes. Design: Prospective cross sectional. Settings: Outpatient. Participants: 412 patients presented with unilateral or bilateral hand numbness suspecting Carpal Tunnel Syndrome (CTS). Exclusion criteria: Cervical spine or hand trauma history, nerve injury history. Interventions: Each patient was subjected to the following; demographic data including occupation, body mass index, detailed medical history including DM history. Neck exam including Spurling test. Full neurological exam. Main outcome measures: Upper extremities Nerve conduction studies and electromyography of segment pointing muscles. Laboratory testing including glycosylated hemoglobin (HgA1c), liver and kidney functions. Cervical spine MRI if possible. Results: Mean age 59.4 ± 11.123. All patients were right-handed, Male 37.1%, female 62.9%, Mean body mass index (BMI) 32.2 ± 8.2. majority were manual workers (55.1%). HgA1c <5.5 has the fewest patients (7.3%), highest number of patients with HgA1c 5.5-6.0. significant relation between HgA1c categories and sensory CTS p=0.001 and sensory motor CTS p=0.001. No significant relation between HgA1c categories and demyelinating pathology p=0.123 but significant with demyelinating axonal pathology p=0.017. Significant relation between HgA1c and Guyon canal syndrome p=0.001 and polyneuropathy p=0.001. No significance between HgA1c and cervical radiculopathy p=0321. Conclusions: High incidence of DM and pre-diabetes among patients with hand nerve entrapment: CTS, Guyon syndrome together with polyneuropathy. EN may be the earliest neurophysiological abnormalities in DM, particularly in the upper limbs, even in the absence of a generalized polyneuropathy, or it may be superimposed on a generalized diabetic neuropathy. Due to the metabolic alterations consequent to abnormal glucose metabolism, the peripheral nerves show both functional impairment and structural changes, even in the preclinical stage, making them more prone to entrapment in anatomically constrained channels.
目的:了解手神经卡压综合征患者糖尿病(DM)/糖尿病前期的发病率。设计:前瞻性横断面。设置:门诊。参与者:412例单侧或双侧手部麻木怀疑腕管综合征(CTS)的患者。排除标准:颈椎或手部外伤史,神经损伤史。干预措施:每位患者接受以下治疗;人口统计资料,包括职业、身体质量指数、详细病史,包括糖尿病史。颈部检查包括斯普林试验。全面的神经学检查。主要观察指标:上肢神经传导及节段指向肌肌电图。实验室检查包括糖化血红蛋白(HgA1c)、肝肾功能。如果可能的话,颈椎MRI。结果:平均年龄59.4±11.123岁。所有患者均为右撇子,男性37.1%,女性62.9%,平均体重指数(BMI) 32.2±8.2。体力劳动者居多(55.1%)。HgA1c <5.5的患者最少(7.3%),HgA1c 5.5 ~ 6.0的患者最多。HgA1c分类与感觉CTS和感觉运动CTS有显著相关性p=0.001。HgA1c分型与脱髓鞘病理无显著相关性(p=0.123),与脱髓鞘轴突病理有显著相关性(p=0.017)。HgA1c与Guyon管综合征p=0.001、多神经病变p=0.001有显著相关性。HgA1c与颈神经根病无显著关系p=0321。结论:手神经卡压患者中糖尿病和糖尿病前期的发生率较高:CTS、Guyon综合征合并多神经病变。EN可能是DM中最早的神经生理异常,特别是在上肢,即使没有全身性多神经病变,也可能叠加在全身性糖尿病神经病变上。由于糖代谢异常引起的代谢改变,即使在临床前阶段,周围神经也表现出功能损伤和结构改变,使它们更容易被困在解剖受限的通道中。
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引用次数: 0
Sustaining Good Mental Health in the Face of Health and Political Crisis 面对健康和政治危机,保持良好的精神健康
Pub Date : 2021-01-01 DOI: 10.35248/2329-9096.21.9.595
A. Weinberg
Good mental health should be free to all. However, the many factors that contribute to our daily and longer-term psychological well-being are rarely constant and where we need support finances are often a consideration, whether our own or those of the health services on offer. Furthermore, access to positive experiences of mental health is governed by a host of everyday and dispositional variables, over which we have limited control. This is certainly true of the workplace as elsewhere and the last decade has seen unprecedented progress in developing national strategies around the world to support mental health at work. However, in times of change and uncertainty, risks to psychological well-being increase and so this has proved during the waves of fear and loss during the COVID-19 pandemic, further fuelled by anxieties accompanying economic and political tensions and highlighted through inequalities, poverty and protest. This commentary considers the role of appropriate guidance for workplaces in relation to the mental health of employees, taking the UK as a case study example in times of economic and political challenge (e.g. Brexit) as well as the health emergency shared by all.
良好的心理健康应该对所有人免费。然而,促进我们日常和长期心理健康的许多因素很少是恒定的,我们需要财政支持的地方往往是一个考虑因素,无论是我们自己的还是所提供的保健服务。此外,获得积极的心理健康体验是由许多日常和性格变量决定的,我们对这些变量的控制有限。与其他地方一样,工作场所也是如此。过去十年,世界各地在制定支持工作场所精神卫生的国家战略方面取得了前所未有的进展。然而,在变化和不确定的时期,心理健康面临的风险会增加,在2019冠状病毒病大流行期间的恐惧和损失浪潮中就证明了这一点,伴随着经济和政治紧张局势的焦虑进一步加剧了这一点,并通过不平等、贫困和抗议凸显出来。本评论考虑了工作场所在员工心理健康方面的适当指导作用,以英国为例,在经济和政治挑战时期(例如英国脱欧)以及所有人共同面临的卫生紧急情况。
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引用次数: 0
Current Problems of Diagnostics and Treatment of Purulent-Inflammatory Diseases and Sepsis in Medical Practice 脓性炎性疾病和脓毒症在医疗实践中的诊断与治疗现状
Pub Date : 2021-01-01 DOI: 10.4236/IJCM.2021.123011
L. Ostapiuk, A. Voloshinovskii, V. Savchyn, Nataliia Tuziyk, Taras Маlui
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引用次数: 3
Outcome Measures for Motor impairments in Pediatric Attention Deficit Hyperactivity Disorder: A Scoping Review 儿童注意缺陷多动障碍中运动障碍的结果测量:范围综述
Pub Date : 2021-01-01 DOI: 10.35248/2329-9096.21.9.583
Rucha Gadgil, Arwa Kotwal, Isha S. Akulwar
Background: Attention-deficit hyperactivity disorder is identified as a neurobehavioral disorder characterizing inattention, hyperactivity, impulsivity and functional impairment. Motor impairments are rarely part of assessments and typically not treated in ADHD. The outcome measures used for motor impairments lack consensus, limiting a uniform approach to rehabilitation. Therefore, a review of the literature to underline and verify outcome measures for motor impairments in ADHD in the pediatric population is needed. Methodology: A scoping review was conducted following the PRISMA-Sr guidelines to assess and categorize outcome measures used for motor impairments in the pediatric ADHD population. Pubmed Central, Embase, and the Cochrane Library were searched for publications between 2009-2019 that reported on Motor impairments in pediatric ADHD and mentioned related outcome measures. The data are presented using a ‘narrative review’ or descriptive analysis of the contextual or process-oriented data and simple quantitative analysis using descriptive statistics. Results: 22 studies were included: 4 randomized controlled trials, 11 observational studies, and 7 experimental studies. The outcome measures found in the studies showed a divided application with no uniformity in their use as a prognostic or diagnostic measure. Conclusion: This review highlights the lack of uniformity in the outcome measures used for motor impairments in pediatric ADHD.
背景:注意缺陷多动障碍是一种以注意力不集中、多动、冲动和功能障碍为特征的神经行为障碍。运动障碍很少是评估的一部分,通常不治疗多动症。用于运动障碍的结果测量缺乏共识,限制了统一的康复方法。因此,需要对文献进行回顾,以强调和验证小儿ADHD人群中运动障碍的结果测量。方法:根据PRISMA-Sr指南进行范围审查,以评估和分类用于儿童ADHD人群运动障碍的结果测量。Pubmed Central、Embase和Cochrane图书馆检索了2009-2019年期间报告儿童ADHD运动障碍并提到相关结果测量的出版物。数据使用“叙述性回顾”或对上下文或面向过程的数据进行描述性分析,并使用描述性统计进行简单的定量分析。结果:共纳入22项研究:随机对照研究4项,观察性研究11项,实验性研究7项。在研究中发现的结果测量显示,作为预后或诊断测量,它们的应用是分散的,没有一致性。结论:这篇综述强调了小儿多动症运动障碍的结果测量缺乏一致性。
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引用次数: 0
Safe Physiotherapy Practice During Covid-19 Pandemic-A Compilation of Guidelines and Recommendation from Different Organisation Covid-19大流行期间的安全物理治疗实践-不同组织的指南和建议汇编
Pub Date : 2021-01-01 DOI: 10.35248/2329-9096.21.S6.007
P. Bastola
Corona virus disease 2019 (COVID-19) has spread quickly around the world, and WHO categorized it as a pandemic in March, 2020. In India more than one million people have been infected with corona virus disease till date. In this situation, the entire healthcare system and healthcare staff need to respond in a very short time to an exponential growth of the number of COVID-19 patients. The SARS-CoV-2 virus is transmitted from person to person by large droplets from infected person by coughing, sneezing or rhino-rhea. An approximate distance of 2 meters is needed to protect from these droplets. SARS-CoV-2 similar to the other corona virus family which remains on the surface of objects for variable periods of time (at least 24 hours on hard surfaces and up to 8 hours on soft surfaces). Healthy people may get infected with this virus through touching the mouth, nose, or eyes with a contaminated hand. Infected droplets which were created during a sneeze or cough persist in the air for about 3 hours. It also reaffirms Standard Precautions as the foundation for preventing transmission of infectious agents during patient care in all healthcare settings by compiling different guidelines/ recommendation of various organizations and institutions published recently.
2019冠状病毒病(COVID-19)在全球迅速传播,世卫组织于2020年3月将其归类为大流行。迄今为止,印度已有100多万人感染了冠状病毒病。在这种情况下,整个医疗保健系统和医护人员需要在很短的时间内应对COVID-19患者数量的指数级增长。SARS-CoV-2病毒通过感染者的咳嗽、打喷嚏或鼻漏等大飞沫在人与人之间传播。需要大约2米的距离来保护这些液滴。SARS-CoV-2与其他冠状病毒家族相似,可在物体表面停留不同的时间(在坚硬表面上至少24小时,在柔软表面上长达8小时)。健康人可能通过用被污染的手接触口、鼻或眼睛而感染这种病毒。打喷嚏或咳嗽时产生的受感染飞沫在空气中持续约3小时。它还重申《标准预防措施》是在所有卫生保健环境中通过汇编最近出版的各种组织和机构的不同指南/建议来预防患者护理期间传染原的基础。
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引用次数: 0
Design and Performance of BIT Lexochair, a Robotic Leg-Exoskeleton Assistive Wheelchair 机器人腿部外骨骼辅助轮椅BIT Lexochair的设计与性能研究
Pub Date : 2021-01-01 DOI: 10.35248/2329-9096.21.9.581
Gao Huang, M. Ceccarelli, Weimin Zhang, Qiang Huang
The BIT LExoChair wheelchair for motion assistance was designed as a solution with a modular design for user’s locomotion mobility with the aim of assisting autonomy, exercising, and rehabilitation, with activities in design, experimental validation, and implementation that are summarized in the main listed references [1-11], as referring to the patent files [1,2]. This mini-review is based on illustration from the references papers as summary of the work and results in developing the BIT LExoChair wheelchair towards practical market availability in a near-future.
BIT LExoChair运动辅助轮椅被设计为一种模块化设计的解决方案,旨在帮助用户的运动能力,运动和康复,其设计,实验验证和实施的活动在主要列出的参考文献[1-11]中进行了总结,参考了专利文件[1,2]。这篇小型综述是基于参考文献中的插图,总结了在不久的将来将BIT LExoChair轮椅推向实际市场的工作和结果。
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引用次数: 1
Is There Any Relationship between Frequency of Shoulder Impingement Steroid Injection and Diabetes Mellitus 肩关节撞击类固醇注射频率与糖尿病有关系吗
Pub Date : 2021-01-01 DOI: 10.35248/2329-9096.21.S5.004
Naglaa A. Hussein, M. Bartels, Mark Thomas
Objective: Determine the relationship between frequency of steroid injections, duration between injections and diabetic status among shoulder impingement patients. Design: Retrospective. Setting: Outpatient. Participants: Charts of 412 patients presented with unilateral or bilateral shoulder pain diagnosed shoulder impingement syndrome and treated with steroid injections over a period of 01/2019-12/2020. Exclusion criteria: Those having manifestations suggesting of cervical radiculopathy, neuromuscular diseases, or shoulder trauma history. Interventions: Reviewing and collecting patient charts data; demographic data including occupation, body mass index, detailed medical history including DM history. Shoulder exam including impingement provocative tests; Hawkins test, Neer’s sign. Neck exam including Spurling test. Full neurological exam. Main outcome measures: Number of steroid injections received and duration between each injection over past 2 years. Laboratory results: Glycosylated hemoglobin (HgA1c), liver and kidney functions. MRI shoulder results if available. Results: Mean age 59.4 ± 11.123. All patients were right-handed, Male 37.1%, female 62.9%, Mean body mass index (BMI) 32.2 ± 8.2. Majority were manual workers (55.1%). significant relationship between shoulder impingement and sex and BMI. HgA1c <5.5 has the fewest patients (7.3%), highest number of patients with HgA1c 5.5-6.0. significant incidence of shoulder impingement with rising category of HgA1c with highest among HgA1c >7 (p=0.0001) with significant bilateral disease. Significant incidence of shoulder impingement (unilateral or bilateral among diabetics (HgA1c>6) compared to non- diabetics (p=0.011). Mean number of injections among diabetics 1.1756 ± 1.17283, non-diabetics 0.6391 ± 0.89051 (p=0.0001). No significant relation between DM and duration between injections (p=0.129). Conclusion: Steroid injection has proven efficacy in diabetic shoulder impingement patients. No studies discussed effect of DM on frequency of steroid injection. This study showed that presence of DM among shoulder impingement patients significantly increases the frequency of steroid injection but not affecting duration between injections.
目的:探讨肩撞击患者类固醇注射频率、注射时间与糖尿病状态的关系。设计:回顾性。设置:门诊。参与者:在2019年1月1日至2020年12月期间,412名诊断为肩撞击综合征并接受类固醇注射治疗的单侧或双侧肩痛患者的图表。排除标准:有颈椎神经根病、神经肌肉疾病或肩部创伤史的患者。干预措施:审查和收集患者病历数据;人口统计资料,包括职业、身体质量指数、详细病史,包括糖尿病史。肩部检查,包括撞击刺激试验;霍金斯测试,诺氏征兆。颈部检查包括斯普林试验。全面的神经学检查。主要观察指标:过去2年内接受类固醇注射的次数和每次注射的持续时间。实验室结果:糖化血红蛋白(HgA1c)、肝肾功能。肩关节MRI结果(如有)。结果:平均年龄59.4±11.123岁。所有患者均为右撇子,男性37.1%,女性62.9%,平均体重指数(BMI) 32.2±8.2。体力劳动者居多(55.1%)。肩关节撞击与性别和BMI有显著关系。HgA1c为7 (p=0.0001),双侧病变显著。与非糖尿病患者相比,糖尿病患者(HgA1c>6)肩关节撞击(单侧或双侧)的发生率显著(p=0.011)。糖尿病患者平均注射次数为1.1756±1.17283次,非糖尿病患者平均注射次数为0.6391±0.89051次(p=0.0001)。DM与注射时间无显著相关性(p=0.129)。结论:类固醇注射治疗糖尿病性肩关节撞击有较好的疗效。没有研究讨论DM对类固醇注射频率的影响。本研究表明,肩关节撞击患者中糖尿病的存在显著增加了类固醇注射的频率,但不影响注射间隔时间。
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引用次数: 0
Cerebral Palsy Life Expectancy: Discrepancies between Literature and Community Data 脑瘫预期寿命:文献与社区数据的差异
Pub Date : 2021-01-01 DOI: 10.35248/2329-9096.21.9.606
Craig H Lichtblau
Cerebral palsy patients and their families need to predict patients’ length of survival for emotional, medical, and financial planning reasons. Providing these estimations is wrought with challenges, some of which are specific to the significant variations in survival that are observed amongst this group of patients. The statistical models that are used to assess life expectancy are plagued by mathematical limitations, faulty assumptions, and the exclusion of factors that are critical to prognosis. In this commentary, we provide evidence that the medical community generally underestimates life expectancy in cerebral palsy. With medical innovations extending lives, some of the literature on life expectancy is outdated, but old data does not explain the extent of the discrepancies we see between what we observe in our communities and what is espoused in the literature. Herein, we offer potential explanations for these discrepancies and call on the medical community to improve predictions of survival in cerebral palsy patients so that they can get the care they need. The harms and dangers of biased life expectancy data cannot be overstated, and cerebral palsy patients are consistently living longer than the current literature would suggest. We demonstrate here why life expectancy models underestimate cerebral palsy survival in the community.
脑瘫患者和他们的家人需要预测患者的生存时间的情绪,医疗和财务规划的原因。提供这些估计是充满挑战的,其中一些是特定于在这组患者中观察到的生存的显着变化。用于评估预期寿命的统计模型受到数学限制、错误假设和排除对预后至关重要的因素的困扰。在这篇评论中,我们提供的证据表明,医学界普遍低估了脑瘫患者的预期寿命。随着医疗创新延长寿命,一些关于预期寿命的文献已经过时,但旧数据并不能解释我们在社区中观察到的情况与文献中所支持的情况之间的差异程度。在此,我们为这些差异提供了可能的解释,并呼吁医学界提高脑瘫患者的生存预测,以便他们能够得到他们需要的护理。有偏见的预期寿命数据的危害和危险不能被夸大,脑瘫患者的寿命一直比目前文献所显示的要长。我们在这里证明了为什么预期寿命模型低估了社区中脑瘫的存活率。
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引用次数: 0
Pain Mechanisms in Spinal Nerve Root Entrapment 脊神经根压迫的疼痛机制
Pub Date : 2021-01-01 DOI: 10.35248/2329-9096.21.9.584
Naglaa A. Hussein
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引用次数: 0
Incidence of Diabetes Mellitus Type II and Pre-Diabetes among Shoulder Impingement Syndrome Patients and Related Modifying Factors: Epidemiological Study 肩撞击综合征患者糖尿病II型及前驱糖尿病发病率及相关影响因素的流行病学研究
Pub Date : 2021-01-01 DOI: 10.35248/2329-9096.21.9.605
Naglaa A. Hussein, M. Bartels, Mark G. Thomas, David Z. Prince
Objective: Measure the incidence of Diabetes Mellitus (DM) among patients with shoulder impingement syndrome and the factors that can modify that disease. Design: Prospective. Settings: Outpatient. Participants: 412 patients presented with unilateral or bilateral shoulder pain suspecting shoulder impingement neuromuscular diseases, or syndrome. Exclusion criteria: Those having manifestations suggesting of cervical radiculopathy, shoulder trauma history. Interventions: Each patient was subjected to the following; demographic data including occupation, body mass index, detailed medical history including DM history. Shoulder exam including impingement provocative tests; Hawkin test, Neer’s sign. Neck exam including Spurling test. Full neurological exam. Main outcome measures: Laboratory testing including glycosylated hemoglobin (HgA1c), liver and kidney functions. Shoulder MRI if possible. Results: Mean age 59.4 ± 11.123. All patients were right-handed, Male 37.1%, female 62.9%, Mean body mass index (BMI) 32.2 ± 8.2. Majority were manual workers (55.1%). No significant relationship between shoulder impingement sex but significant with BMI and age. HgA1c <5.5 has the fewest patients (7.3%), highest number of patients with HgA1c 5.5-6.0. significant incidence of shoulder impingement with rising category of HgA1c with highest among Hga1c >7 (p=0.0001) with significant bilateral disease. Significant incidence of shoulder impingement (unilateral or bilateral among diabetics (HgA1c >6) compared to non- diabetics (p=0.011). Conclusions: High incidence of DM /prediabetes among shoulder impingement patients. Level of HgA1c significantly proportionate to incidence and laterality. This suggests that it is part of musculoskeletal complication of DM. that can evidently occur with prediabetes status. Body mass index and age significantly affected the incidence but not the sex.
目的:了解肩关节撞击综合征患者糖尿病(DM)的发病率及其影响因素。设计:前瞻性。设置:门诊。参与者:412名患者提出单侧或双侧肩痛怀疑肩撞击神经肌肉疾病,或综合征。排除标准:有颈椎神经根病、肩部外伤史者。干预措施:每位患者接受以下治疗;人口统计资料,包括职业、身体质量指数、详细病史,包括糖尿病史。肩部检查,包括撞击刺激试验;霍金检验,诺氏征。颈部检查包括斯普林试验。全面的神经学检查。主要观察指标:实验室检测包括糖化血红蛋白(HgA1c)、肝肾功能。如果可能的话。结果:平均年龄59.4±11.123岁。所有患者均为右撇子,男性37.1%,女性62.9%,平均体重指数(BMI) 32.2±8.2。体力劳动者居多(55.1%)。肩关节撞击与性别无显著关系,但与BMI和年龄有显著关系。HgA1c为7 (p=0.0001),双侧病变显著。与非糖尿病患者相比,糖尿病患者(HgA1c >6)肩关节撞击(单侧或双侧)的发生率显著(p=0.011)。结论:肩关节撞击患者中糖尿病/前驱糖尿病的发生率较高。HgA1c水平与发病率和侧边度成显著比例。这表明它是糖尿病前期明显发生的肌肉骨骼并发症的一部分。体重指数和年龄对发病率有显著影响,而性别对发病率无显著影响。
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引用次数: 1
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International Journal of Physical Medicine and Rehabilitation
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