International journal of oral surgery最新文献

The effect of resection of the apical part of the root before replantation upon periodontal and pulpal healing was studied in 7 green Vervet monkeys (Cercopithecus aethiops) using teeth with incomplete and complete root formation. Maxillary central incisors, mandibular lateral incisors and first and second mandibular molars were used in this experiment. On one side, the tooth was extracted and replanted with an intact root while the contralateral tooth had 2 mm of the apex resected for the purpose of facilitating pulpal repair and eliminating resorption in the resorption-prone region of the root. The replanted teeth were examined histologically 8 weeks after replantation. The histometric analysis revealed no significant difference in periodontal healing between teeth with or without apical resection. With regard to pulpal healing, apical resection was found to lead to significantly less vital pulp tissue in teeth with immature root formation. A similar, but not significant difference was found for mature teeth. Based on these findings, it could not be recommended that apices be resected prior to replantation in order to improve pulpal repair.

Human fibroblast interferon (HuIFN-β) was topically administered to 20 premalignant lesions histopathologically showing epithelial dysplasia such as leukoplakia and lichen planus which arose in the oral mucosa. HuIFN-β was prepared in the water-soluble gel form containing 2% carboxymethylcellose, 45% glycelin, 0.1 M citrate buffer (pH 4.5) and 0.2% SDS as stabilizing agents. This preparation was found to be effective for herpetic gingivostomatitis and zostal lesions arising along the intercostal nerve. Thus, the HuIFN-β preparation (10⁴ to 5 × 10³ IU) was applied to the oral mucosal lesion for 1 h twice a week. The lesion with topical administration of HulFN-β was covered tightly with the mucosal bandage which was coated with carboxymethylcellulose, glycelin and CaCl₂ on vinyl acetate matrix. The 14 oral lesions with erosion or ulcer formation accompanied by severe pain by touch, had complete remission after approximately 10 successive applications of this preparation. Although subjective symptoms such as irritation pain in the other 6 patients with severe hyperkeratotic lesion subsided, white coatings and streaks could not be completely removed by this therapy. No other side-effects excluding slight pain and reddish swelling which occurred intermittently during HuIFN-β administration were observed.

Radicular cysts arising from deciduous teeth are rare. 28 such cases have been recorded in the literature since 1898. In this study, we present 23 personally-observed cases of radicular cysts arising from deciduous teeth. The patients' ages ranged from 4 to 12 years with one exceptional case aged 19 years, The M:F ratio was 1.6:1. The mandible was affected more frequently than the maxilla and the deciduous molars were the teeth most commonly involved. 2 of the cysts presented multi-locular radiolucency; in 9 cases, buccal expansion was noticed and in 8 cases, permanent buds were displaced. Caries was the most common etiologic factor in the formation of the cysts. Histologically, cysts in varying stages of development were lined by proliferating non-keratinized stratified squamous epithelium.

A case of multiple myeloma detected by the first symptom of severe postextraction bleeding was presented. Although laboratory data showed severe anemia, rouleaux formation of erythrocytes, abnormal hemostatic parameters, elevated erythrocyte sedimentation rate and hyper-globulinemia, no involvement of bones such as the jaws, skull, ribs or sternum was demonstrated roentgenologically. Final diagnosis obtained by Immunoelectrophoresis was Ig A · K type myeloma. During a therapeutic period with melphalan and predonine, bleeding from the extracted wound was repeated. 2 months after the onset of the first symptoms, the patient died of systemic bleeding. Autopsy findings revealed many hemorrhagic sites in the lungs, stomach, kidney and bladder and the existence of plasma cell-like tumor cells in the bone marrow of lumber vertebra and sternum.

The diagnosis of actinomycosis is not always straightforward. It has been described as a masquerader, and 2 cases are presented which exemplify this. Their mode of presentation and natural history are contrasted.

The authors, with their experience in the field of dépistage of maxillofacial cancer, propose the establishment of a health education program for prevention and early diagnosis.

The lining of odontogenic cysts seldom gives rise to the development of a carcinoma. In a review of the literature by Gardner in 1975, 25 cases were accepted as such. In the present paper, 5 new cases are reported. These cases were encountered during a 14-year-period in which 292 oral carcinomas were registered, emphasizing the rarity of carcinomas arising from odontogenic cysts.

Experience with 31 mandibular fractures treated by intraoral open reduction techniques is reviewed and the techniques described. A 12.9% complication rate was experienced, no complication causing significant morbidity. Indications for intraoral open reduction are reviewed and the literature is discussed. The intraoral open reduction technique is a satisfactory treatment method for selected cases of fractures of the mandible.

The ultrastructure of 10 lepromatous lesions in the face and the palatal mucosa after different duration and length of treatment was studied. Biopsies taken from patients who showed erythema nodosum leprosum (ENL) revealed different ultrastructural characteristics from those taken from ‘burnt out’ and non-medicated cases. Multiple secondary lysosomes were rarely seen in non-ENL cases. The presence of Mycobacterium leprae and an increased lysosomal activity in ENL reactive cases is interpreted as a reaction to the lysis of the cytoplasmic matrix of M. leprae; however, drug-specific (diaminodiphenylsulphone) reactions must also be considered.