Pub Date : 2023-06-30DOI: 10.7897/2277-4343.140375
A. As, C. Das
Introduction: Bell’s palsy is the most common type of unilateral facial paralysis (60%-75%). The etiopathogenesis of Bell’s palsy is uncertain. The clinical features include acute onset of unilateral facial paralysis, poor eyelid closure, posterior auricular pain, numbness of cheeks, and deviation of the angle of the mouth towards the unaffected side. Bell’s palsy can be understood as Ardita in Ayurveda. Acharya Sushruta has included bala as a susceptible group while describing the vishesha nidanas of Ardita. Aims and Ideas: To study the effect of a framed Ayurvedic treatment protocol in managing chronic residual Bell’s palsy in children. Methods: The present case was a chronic right-sided residual Bell’s palsy with a history of 12 years and was approached through the line of management of Ardita mentioned in Bruhattrayees and Yogamrutam for 12 days. The treatment was started with takra dhara to give mrdu rookshana. Takra dhara mukha abhyanga and ksheera dhoomam were administered, followed by marsha nasyam. Two specific treatments mentioned in Yogamrutam was adopted in this case, i.e., panasa patra swedam and navaneeta shiro talam. The treatment was ended with shashtika shala pinda swedana to mukha. Results and Discussions: The facial asymmetry was reduced by 60% at the end of the treatment. Watering of the right was subsided entirely, and there was complete effortless closure of the right year after treatment. Pain, twitching and numbness on the right half of the face were utterly absent. The House and Brackmann grade was reduced from Grade III to Grade II after 12 days of treatment.
{"title":"AYURVEDIC APPROACH TO TREAT CHRONIC RESIDUAL BELL’S PALSY IN CHILDREN: A CASE REPORT","authors":"A. As, C. Das","doi":"10.7897/2277-4343.140375","DOIUrl":"https://doi.org/10.7897/2277-4343.140375","url":null,"abstract":"Introduction: Bell’s palsy is the most common type of unilateral facial paralysis (60%-75%). The etiopathogenesis of Bell’s palsy is uncertain. The clinical features include acute onset of unilateral facial paralysis, poor eyelid closure, posterior auricular pain, numbness of cheeks, and deviation of the angle of the mouth towards the unaffected side. Bell’s palsy can be understood as Ardita in Ayurveda. Acharya Sushruta has included bala as a susceptible group while describing the vishesha nidanas of Ardita. Aims and Ideas: To study the effect of a framed Ayurvedic treatment protocol in managing chronic residual Bell’s palsy in children. Methods: The present case was a chronic right-sided residual Bell’s palsy with a history of 12 years and was approached through the line of management of Ardita mentioned in Bruhattrayees and Yogamrutam for 12 days. The treatment was started with takra dhara to give mrdu rookshana. Takra dhara mukha abhyanga and ksheera dhoomam were administered, followed by marsha nasyam. Two specific treatments mentioned in Yogamrutam was adopted in this case, i.e., panasa patra swedam and navaneeta shiro talam. The treatment was ended with shashtika shala pinda swedana to mukha. Results and Discussions: The facial asymmetry was reduced by 60% at the end of the treatment. Watering of the right was subsided entirely, and there was complete effortless closure of the right year after treatment. Pain, twitching and numbness on the right half of the face were utterly absent. The House and Brackmann grade was reduced from Grade III to Grade II after 12 days of treatment.","PeriodicalId":14253,"journal":{"name":"International journal of research in ayurveda and pharmacy","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87553783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-30DOI: 10.7897/2277-4343.140398
Shiwali Sharma, U. Sharma, Shuchi Mitra, K. Sharma
If used wisely, science is a boon to humanity and, if misused, can be hazardous. Ayurveda is one of the primordial systems of medical science that has elaborated the causes and methods of drug-induced consequences and preventive measures. Every system has some flaws, which need to be noted and rectified no matter how excellent the system is. In rasoushadhis (herbomineral formulations) preparation, specific techniques like shodhana, jarana and marana etc., have been developed to prepare more bio-assimilable forms of rasaushadha dravya. The indications, dose, vehicle, period of drug administration, interval or duration of treatment, diagnosis of the disease, nature or prakriti of the patient, pathya-apathya (favourable-unfavourable regimen) etc., are significant factors that the physician should always consider before they recommend these rasoushadhis to the patients. This review compiles the standard procedures which are adopted during the preparation of rasoushadhis like Shodhana, and Marana, the utility of rasoushadhis in Ashtanga Ayurveda, skin diseases, lifestyle disorders etc. and the rational use of rasoushadhis to understand and highlight the importance and uniqueness of rasoushadhis.
{"title":"IMPORTANCE OF RASOUSHADHIS IN AYURVEDA: A REVIEW","authors":"Shiwali Sharma, U. Sharma, Shuchi Mitra, K. Sharma","doi":"10.7897/2277-4343.140398","DOIUrl":"https://doi.org/10.7897/2277-4343.140398","url":null,"abstract":"If used wisely, science is a boon to humanity and, if misused, can be hazardous. Ayurveda is one of the primordial systems of medical science that has elaborated the causes and methods of drug-induced consequences and preventive measures. Every system has some flaws, which need to be noted and rectified no matter how excellent the system is. In rasoushadhis (herbomineral formulations) preparation, specific techniques like shodhana, jarana and marana etc., have been developed to prepare more bio-assimilable forms of rasaushadha dravya. The indications, dose, vehicle, period of drug administration, interval or duration of treatment, diagnosis of the disease, nature or prakriti of the patient, pathya-apathya (favourable-unfavourable regimen) etc., are significant factors that the physician should always consider before they recommend these rasoushadhis to the patients. This review compiles the standard procedures which are adopted during the preparation of rasoushadhis like Shodhana, and Marana, the utility of rasoushadhis in Ashtanga Ayurveda, skin diseases, lifestyle disorders etc. and the rational use of rasoushadhis to understand and highlight the importance and uniqueness of rasoushadhis.","PeriodicalId":14253,"journal":{"name":"International journal of research in ayurveda and pharmacy","volume":"21 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91547065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-30DOI: 10.7897/2277-4343.140370
Jyoti N. Shinde, Vaishnavi H. Hande, Sandesh Khobragade
Aim: To evaluate the effect of local application of Utsadaniya lepa (Application of herbal paste to a wound-producing granulation) in wound bed preparation. Materials and methods: A surgically created deep wound was managed with the local application of lepa of Utsadaniya dravyas (drugs) mixed with goghruta (ghee). Jalaukavacharana (leech therapy) and vrana dhavana (washing) with Triphala kwatha were also administered as adjuvant medication. Observation: Utsadaniya lepa has an important role in enhancing the process of granulation formation in shuddha vrana. Result: Post debridement deep wound on the dorsum of the right foot was treated successfully with Utsadaniya lepa to achieve wound bed preparation for further surgical intervention, i.e., split skin grafting. Conclusion: Utsadaniya lepa effectively reduces the wound's depth by accelerating the process of granulation formation.
{"title":"EFFECT OF UTSADANIYA LEPA IN WOUND BED PREPARATION: A CASE REPORT","authors":"Jyoti N. Shinde, Vaishnavi H. Hande, Sandesh Khobragade","doi":"10.7897/2277-4343.140370","DOIUrl":"https://doi.org/10.7897/2277-4343.140370","url":null,"abstract":"Aim: To evaluate the effect of local application of Utsadaniya lepa (Application of herbal paste to a wound-producing granulation) in wound bed preparation. Materials and methods: A surgically created deep wound was managed with the local application of lepa of Utsadaniya dravyas (drugs) mixed with goghruta (ghee). Jalaukavacharana (leech therapy) and vrana dhavana (washing) with Triphala kwatha were also administered as adjuvant medication. Observation: Utsadaniya lepa has an important role in enhancing the process of granulation formation in shuddha vrana. Result: Post debridement deep wound on the dorsum of the right foot was treated successfully with Utsadaniya lepa to achieve wound bed preparation for further surgical intervention, i.e., split skin grafting. Conclusion: Utsadaniya lepa effectively reduces the wound's depth by accelerating the process of granulation formation.","PeriodicalId":14253,"journal":{"name":"International journal of research in ayurveda and pharmacy","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90445025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-30DOI: 10.7897/2277-4343.140384
G. Dhivya, H. Kumari, H. Sofia, T. Kantham, R. Kumari
Background: Peenisam (sinusitis) is a widespread condition, and patients are visiting Ayothidass Pandithar Hospital, National Institute of Siddha, to manage this condition. The signs and symptoms of peenisam (sinusitis) are mentioned in Siddha literature Yugi vaithya chinthamani, such as lacrimation, nasal block, headache, rhinorrhea, cough, absence of taste, may be correlated with maxillary sinusitis in biomedicine. Objectives: To evaluate the clinical effectiveness of Siddha formulations Sombu theeneer (internal) and Peenisathirku thailam (external) in the management of sinusitis by using Adelaide Disease Severity Score (ADSS) and to observe changes in clinical lab parameters, total count, differential count, erythrocyte sedimentation rate, absolute eosinophil count and serum immunoglobulin E pre and post-treatment. Methods: An open Non-Randomised clinical trial with a sample size of 10 patients diagnosed with Peenisam within the age limit of 18-60 years. The approval was obtained from Institutional Ethical Committee for conducting this clinical study with the IEC No: (25/11/2021; NIS/IEC/2021/MP-3). It was registered prospectively in the Clinical Trail Registry of India (CTRI Reg No: CTRI/2022/01/051045). The trial drug Sombu theeneer (internal) 30 ml BD with water after food and Peenisathirku thailam (external) were given for 48 days and two months follow up without the trial drug. Results: Biostatistical reports of ADSS scores and lab investigations before and after treatment were statistically analysed using paired t-tests. There was a significant reduction in both the ADSS.
{"title":"PILOT STUDY ON EFFECTIVENESS OF SIDDHA MEDICINES SOMBU THEENEER (INTERNAL) AND PEENISATHIRKU THAILAM (EXTERNAL) IN THE MANAGEMENT OF PEENISAM (SINUSITIS)","authors":"G. Dhivya, H. Kumari, H. Sofia, T. Kantham, R. Kumari","doi":"10.7897/2277-4343.140384","DOIUrl":"https://doi.org/10.7897/2277-4343.140384","url":null,"abstract":"Background: Peenisam (sinusitis) is a widespread condition, and patients are visiting Ayothidass Pandithar Hospital, National Institute of Siddha, to manage this condition. The signs and symptoms of peenisam (sinusitis) are mentioned in Siddha literature Yugi vaithya chinthamani, such as lacrimation, nasal block, headache, rhinorrhea, cough, absence of taste, may be correlated with maxillary sinusitis in biomedicine. Objectives: To evaluate the clinical effectiveness of Siddha formulations Sombu theeneer (internal) and Peenisathirku thailam (external) in the management of sinusitis by using Adelaide Disease Severity Score (ADSS) and to observe changes in clinical lab parameters, total count, differential count, erythrocyte sedimentation rate, absolute eosinophil count and serum immunoglobulin E pre and post-treatment. Methods: An open Non-Randomised clinical trial with a sample size of 10 patients diagnosed with Peenisam within the age limit of 18-60 years. The approval was obtained from Institutional Ethical Committee for conducting this clinical study with the IEC No: (25/11/2021; NIS/IEC/2021/MP-3). It was registered prospectively in the Clinical Trail Registry of India (CTRI Reg No: CTRI/2022/01/051045). The trial drug Sombu theeneer (internal) 30 ml BD with water after food and Peenisathirku thailam (external) were given for 48 days and two months follow up without the trial drug. Results: Biostatistical reports of ADSS scores and lab investigations before and after treatment were statistically analysed using paired t-tests. There was a significant reduction in both the ADSS.","PeriodicalId":14253,"journal":{"name":"International journal of research in ayurveda and pharmacy","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84510569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-30DOI: 10.7897/2277-4343.140389
O. Surekha, A. Swaroopa, P. Babu
The main fundamental concept of Ayurveda is to preserve the health of a healthy person and cure the disease of an unhealthy person, i.e., prevention and cure. Acharya Charaka has enumerated various rasayana at the very beginning of chikitsa sthana, which explains the role of prevention that comes prior to cure in Ayurveda. In autoimmunity and their diseases, where the cause is unknown, a person's immune system reacts to self-proteins causing various inflammations, fevers, etc., destroying body tissues and changes in organ functioning, leading to more significant morbidities over time. While treating these conditions, the primary objective of a physician should be relieving the patient’s symptoms and correcting the imbalance created in his immune system without further compromising it. Here comes Ayurveda, the ancient holistic science of life, where acharyas have provided various formulations, purificatory mechanisms, and rejuvenator elixirs in treating such exasperating diseases with the concept called “Ama” by correcting the agni the Élan vital of life. The imperfectly digested anna rasa due to impaired agni is known as ama. The present article lists all possible treatments for treating sama conditions with special reference to autoimmune diseases.
{"title":"TREATMENT MODALITIES IN TREATING AMA CONDITIONS WITH SPECIAL REFERENCE TO AUTOIMMUNE DISEASES: A REVIEW","authors":"O. Surekha, A. Swaroopa, P. Babu","doi":"10.7897/2277-4343.140389","DOIUrl":"https://doi.org/10.7897/2277-4343.140389","url":null,"abstract":"The main fundamental concept of Ayurveda is to preserve the health of a healthy person and cure the disease of an unhealthy person, i.e., prevention and cure. Acharya Charaka has enumerated various rasayana at the very beginning of chikitsa sthana, which explains the role of prevention that comes prior to cure in Ayurveda. In autoimmunity and their diseases, where the cause is unknown, a person's immune system reacts to self-proteins causing various inflammations, fevers, etc., destroying body tissues and changes in organ functioning, leading to more significant morbidities over time. While treating these conditions, the primary objective of a physician should be relieving the patient’s symptoms and correcting the imbalance created in his immune system without further compromising it. Here comes Ayurveda, the ancient holistic science of life, where acharyas have provided various formulations, purificatory mechanisms, and rejuvenator elixirs in treating such exasperating diseases with the concept called “Ama” by correcting the agni the Élan vital of life. The imperfectly digested anna rasa due to impaired agni is known as ama. The present article lists all possible treatments for treating sama conditions with special reference to autoimmune diseases.","PeriodicalId":14253,"journal":{"name":"International journal of research in ayurveda and pharmacy","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87970949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hridroga is the most critical ailment described in Ayurveda. Vataja (cardiovascular disorder) is a form of Hridroga that can be distinguished by pathological symptoms described in Ayurveda. It manifests as ruja in urah pradesha (chest discomfort) and other signs and symptoms such as alpanidrata, shvasavrodha, darah, hrutdrava, stambha, stabadha, akasmat deenata, shoka, bhaya, shabdasehsnuta, shunyata, vepathu, and vestana. Ayurveda has a deficit in assessing disease symptoms using standard parameters. In order to diagnose a disease, it is necessary to do an assessment. Vataj Hridroga symptoms include hritshunya bhava, hrit-shosha, bheda and stambha, and moha-murccha. It is primarily due to Vata vitiation. Shaman chikitsa is the most effective treatment for Vataj Hridroga. Classical literature on Vataj Hridroga and Haritakyadi ghritapaan from Charaka Samhita was studied as a source of information. The drugs used to make Haritakyadi ghrita from Bhavaprakasa Nighantu. The literature mentions observations on nidana, samprapti, Vataj Hridroga's rupa, Haritakyadi ghritapaan, and drugs.
{"title":"AYURVEDIC DRUGS IN MANAGEMENT AND UPAKARMA OF VATAJA HRIDROGA: A REVIEW","authors":"Sanjana Yadav, Sejal Mhatre, Shrutika Dongre, Vaibhav Maheshwari, Reshma Pore","doi":"10.7897/2277-4343.140394","DOIUrl":"https://doi.org/10.7897/2277-4343.140394","url":null,"abstract":"Hridroga is the most critical ailment described in Ayurveda. Vataja (cardiovascular disorder) is a form of Hridroga that can be distinguished by pathological symptoms described in Ayurveda. It manifests as ruja in urah pradesha (chest discomfort) and other signs and symptoms such as alpanidrata, shvasavrodha, darah, hrutdrava, stambha, stabadha, akasmat deenata, shoka, bhaya, shabdasehsnuta, shunyata, vepathu, and vestana. Ayurveda has a deficit in assessing disease symptoms using standard parameters. In order to diagnose a disease, it is necessary to do an assessment. Vataj Hridroga symptoms include hritshunya bhava, hrit-shosha, bheda and stambha, and moha-murccha. It is primarily due to Vata vitiation. Shaman chikitsa is the most effective treatment for Vataj Hridroga. Classical literature on Vataj Hridroga and Haritakyadi ghritapaan from Charaka Samhita was studied as a source of information. The drugs used to make Haritakyadi ghrita from Bhavaprakasa Nighantu. The literature mentions observations on nidana, samprapti, Vataj Hridroga's rupa, Haritakyadi ghritapaan, and drugs.","PeriodicalId":14253,"journal":{"name":"International journal of research in ayurveda and pharmacy","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86900091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-30DOI: 10.7897/2277-4343.140371
B. Gadve, Kiran D. Wagh
Introduction: Warts, also known as Verrucae, is a common dermatological condition caused by Human Papilloma Virus (HPV). A wart is generally a small, rough growth typically on human hands or feet but often in other locations that can resemble a cauliflower or a solid blister. According to Ayurveda, this ailment can be compared with Charmakeela, one of the kshudrarogas. Case presentation: A 65-year-old male patient visited OPD complaining of pedunculated growth over the left thigh region, occasionally feeling itching and discomfort at the growth site. Routine blood and urine examination were done and found within normal range. Diagnosis and management: Based on clinical features, the case was diagnosed as a wart (Charmakeela) and suggested for a Ksharasutra ligation procedure on an OPD basis. Treatment aims to destruct hyperkeratotic overgrown skin and to avoid recurrence. Outcome: There was marked improvement in the wart after Ksharasutra ligation; gradually, the wart detached from its base, leaving a minimal scar. Discussion: Satisfactory results were obtained. This case highlights that Ksharasutra ligation is a very effective and invasive procedure and one of the potential treatments for managing warts.
{"title":"USE OF APAMARGA KSHARSUTRA IN THE MANAGEMENT OF WART (CHARMAKEELA): A CASE STUDY","authors":"B. Gadve, Kiran D. Wagh","doi":"10.7897/2277-4343.140371","DOIUrl":"https://doi.org/10.7897/2277-4343.140371","url":null,"abstract":"Introduction: Warts, also known as Verrucae, is a common dermatological condition caused by Human Papilloma Virus (HPV). A wart is generally a small, rough growth typically on human hands or feet but often in other locations that can resemble a cauliflower or a solid blister. According to Ayurveda, this ailment can be compared with Charmakeela, one of the kshudrarogas. Case presentation: A 65-year-old male patient visited OPD complaining of pedunculated growth over the left thigh region, occasionally feeling itching and discomfort at the growth site. Routine blood and urine examination were done and found within normal range. Diagnosis and management: Based on clinical features, the case was diagnosed as a wart (Charmakeela) and suggested for a Ksharasutra ligation procedure on an OPD basis. Treatment aims to destruct hyperkeratotic overgrown skin and to avoid recurrence. Outcome: There was marked improvement in the wart after Ksharasutra ligation; gradually, the wart detached from its base, leaving a minimal scar. Discussion: Satisfactory results were obtained. This case highlights that Ksharasutra ligation is a very effective and invasive procedure and one of the potential treatments for managing warts.","PeriodicalId":14253,"journal":{"name":"International journal of research in ayurveda and pharmacy","volume":"44 4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83161852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-30DOI: 10.7897/2277-4343.140383
A. Shrirao, M. M. Rahman, PD Mahure, N. Kochar, A. Chandewar
The use of herbal remedies in India has a long history for various medical conditions. High serum total cholesterol, low-density lipoprotein (LDL) concentrations, and a decline in high-density lipoprotein are the main risk factors for coronary heart disease. It has been observed that Butea monosperma L. flower extract and Madhuca longifolia bark extract have been used traditionally to treat hyperglycaemia and related hyperlipidaemia. The evolution of atherosclerotic plaques and coronary artery disease are known to be accelerated by hyperlipidaemia. In the current study, hyperlipidaemic rats were used as a model to examine the potential antihyperlipidemic effects of a hydroalcoholic extract of Butea monosperma L. flowers (HA-BM) and Madhuca longifolia bark (HA-ML). Triton WR 1339 (400 mg/kg) was administered intraperitoneally (i.p.) once to rats to cause hyperlipidaemia, which resulted in rats with persistently high serum levels of triglycerides and cholesterol. The combined dose of HA-BM (200, 400 and 600 mg/kg/day) and HA-ML (250, 500 and 750 mg/kg/day) at a ratio of 1:1 was given to normal and hyperlipidaemic rats. Serum and liver tissue were analysed for lipid profile, and the activity was compared to the cholesterol-lowering drug, atorvastatin (10 mg/kg). From the above study, it could be concluded that a combined dose of an extract of Butea monosperma L. and Madhuca longifolia not only resulted in a significant reduction in cholesterol, triglyceride, LDL, VLDL level but also increased the HDL level, which is good for health.
{"title":"EVALUATION OF COMBINED EFFECT ON ANTIHYPERLIPIDAEMIC ACTIVITY OF MADHUCA LONGIFOLIA AND BUTEA MONOSPERMA L. IN TRITON WR-1339 INDUCED HYPERLIPIDAEMIC RATS","authors":"A. Shrirao, M. M. Rahman, PD Mahure, N. Kochar, A. Chandewar","doi":"10.7897/2277-4343.140383","DOIUrl":"https://doi.org/10.7897/2277-4343.140383","url":null,"abstract":"The use of herbal remedies in India has a long history for various medical conditions. High serum total cholesterol, low-density lipoprotein (LDL) concentrations, and a decline in high-density lipoprotein are the main risk factors for coronary heart disease. It has been observed that Butea monosperma L. flower extract and Madhuca longifolia bark extract have been used traditionally to treat hyperglycaemia and related hyperlipidaemia. The evolution of atherosclerotic plaques and coronary artery disease are known to be accelerated by hyperlipidaemia. In the current study, hyperlipidaemic rats were used as a model to examine the potential antihyperlipidemic effects of a hydroalcoholic extract of Butea monosperma L. flowers (HA-BM) and Madhuca longifolia bark (HA-ML). Triton WR 1339 (400 mg/kg) was administered intraperitoneally (i.p.) once to rats to cause hyperlipidaemia, which resulted in rats with persistently high serum levels of triglycerides and cholesterol. The combined dose of HA-BM (200, 400 and 600 mg/kg/day) and HA-ML (250, 500 and 750 mg/kg/day) at a ratio of 1:1 was given to normal and hyperlipidaemic rats. Serum and liver tissue were analysed for lipid profile, and the activity was compared to the cholesterol-lowering drug, atorvastatin (10 mg/kg). From the above study, it could be concluded that a combined dose of an extract of Butea monosperma L. and Madhuca longifolia not only resulted in a significant reduction in cholesterol, triglyceride, LDL, VLDL level but also increased the HDL level, which is good for health.","PeriodicalId":14253,"journal":{"name":"International journal of research in ayurveda and pharmacy","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73675217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-30DOI: 10.7897/2277-4343.140391
Suwarna D Vyas, Deepak M Vyas, Pragati P Waghmare, . .
Now a day, Ayurveda is gaining wide popularity in the field of cosmetology. Many cosmetic products are prepared and used on the Ayurvedic concepts. Twacha is matruj bhava. The foetus gets varna in the sixth month of intrauterine life. The word "varna" means lustre of the body. Varna is not just colour but includes all the parameters of healthy and radiant skin. Twacha varna varies among different individuals. In Ayurveda twacha varna occurs as per prakriti. According to current medical science, skin colour depends on the amount of melanin and other factors. So here is an attempt to enlist all the factors responsible for varnotpatti.
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Pub Date : 2023-06-30DOI: 10.7897/2277-4343.140390
S. Padma Rani, U. Sharma, Sanjay Singh, K. Sharma
Hair is a valuable anatomical structure of the body, having cosmetological and sociological importance in drafting the beauty and personality of an individual. Greying of hair represents the sign of ageing known as Palitya in Ayurveda. But when hair starts greying before the usual age of onset, known as premature greying of hair. Premature hair greying is called Akalaja Palitya, which occurs due to various factors resulting in the vitiation of Pitta dosha. Due to mankind’s hectic, sedentary and busy schedule, the current scenario is witnessing several challenges, and premature greying of hair is one among them. Premature hair greying has multifactorial aetiology, including oxidative stress, nutritional deficiency, smoking, and dysfunctional thyroid hormones, but the exact aetiology is still unknown. Acharyas have mentioned various rasayana for preventing and treating premature hair greying, i.e., Akalaja Palitya. Rasayana therapy aims primarily to promote the strength and vitality of the body. It also helps maintain the integrity of sapta dhatus (fundamental structural component) by improving digestive power resulting in the sound production of successive dhatus and their malas. Dhatryadi rasayana is a polyherbal formulation consisting of three ingredients, i.e., Dhatri (Emblica officinalis Gaertn.), Bhringraj (Eclipta alba Hassk.) and Tila (Sesamum indicum Linn.). All three plants have the keshya property. Emblica officinalis Gaertn. and Sesamum indicum Linn. both act as a 5α-reductase inhibitor. Eclipta alba Hassk. stimulates the proliferation of follicular keratinocytes by downregulating the TGF-β1 (Transforming Growth Factor Beta 1) expression. Furthermore, all ingredients of Dhatryadi rasayana have antioxidant properties and contribute to essential nutritional supplements required for proper hair development and growth.
头发是一种有价值的身体解剖结构，在塑造一个人的美丽和个性方面具有美容和社会学的重要性。头发变白代表着衰老的迹象，在阿育吠陀中被称为白头病。但是当头发在正常年龄之前开始变白时，被称为头发过早变白。过早的头发变白被称为Akalaja Palitya，这是由于各种因素导致皮塔多莎的破坏而发生的。由于人类忙碌、久坐和繁忙的日程安排，目前的情况见证了几个挑战，过早变白就是其中之一。头发过早变白有多因素的病因，包括氧化应激、营养缺乏、吸烟和甲状腺激素功能失调，但确切的病因尚不清楚。阿查里亚们已经提到了各种预防和治疗过早头发变白的拉萨那，即阿卡拉雅帕利提亚。拉萨那疗法的主要目的是促进身体的力量和活力。它还通过提高消化能力，从而使连续的鱼丸和鱼丸产生良好的效果，帮助维持鱼丸(基本结构成分)的完整性。Dhatryadi rasayana是一种多草药配方，由三种成分组成，即Dhatri (Emblica officinalis Gaertn.)， Bhringraj (Eclipta alba Hassk.)和Tila (Sesamum indicum Linn.)。这三种植物都有keshya属性。政府官员们都很高兴。芝麻和芝麻。两者都是5α-还原酶抑制剂。Eclipta alba hask。通过下调TGF-β1(转化生长因子β1)的表达刺激滤泡角质形成细胞的增殖。此外，梵天的所有成分都具有抗氧化特性，并有助于头发正常发育和生长所需的必要营养补充。
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