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Immune-nutritional indices in female Nigerian breast cancer patients with different tumour characteristics 不同肿瘤特征尼日利亚女性乳腺癌患者的免疫营养指标
Pub Date : 2023-11-03 DOI: 10.51152/jbarbiomed.v9i1.225
Mutiu Jimoh, Ganiyu Arinola
Breast cancer presents varied and complex clinicopathological features which make its management individualistic, prolonged and expensive, thus the need to differentiate each type of breast cancer using cheap and easy to perform investigations. This study evaluated the differentiation potential of extensive immune-nutritional indices which combined serum C-reactive protein (CRP), haemoglobin, albumin levels, blood lymphocyte and platelet counts in breast cancer patients of different status. The aim of this study was to investigate whether pre-treatment Onodera’s prognostic nutritional index (OPNI), CRP-Albumin-Lymphocyte (CALLY) index and the Haemoglobin, Albumin, Lymphocyte and Platelet (HALP) scores differ with breast cancer characteristics. We enrolled a total of 135 consecutive newly diagnosed breast cancer patients who were not on any treatment from Radiation Oncology Department, University College Hospital, Ibadan, Nigeria. Lymphocyte count, platelet count and haemoglobin levels were determined using auto-analyser while serum CRP and albumin levels were measured using ELISA. Immune-nutritional indices (OPNI, CALLY and HALP) were calculated. Haemoglobin concentration, serum albumin level, OPNI, CALLY and HALP were significantly decreased while serum CRP was significantly raised in breast cancer patients compared with control. Mean values of OPNI, CALLY and HALP were significantly decreased in late stage breast cancer patients compared with early stage breast cancer patients, while only CALLY was significantly decreased in poorly differentiated and metastatic breast cancer patients compared with well differentiated and non-metastatic breast cancer patients respectively. This study confirmed the presence of malnutrition and inflammation in breast cancer patients, especially late-stage, poorly differentiated and metastatic groups. This calls for monitoring of liver functions in all cases of breast cancer.
乳腺癌表现出多样而复杂的临床病理特征,这使得其治疗具有个体化、长期和昂贵的特点,因此需要使用廉价和易于进行的检查来区分每种类型的乳腺癌。本研究评价了不同状态乳腺癌患者血清c反应蛋白(CRP)、血红蛋白、白蛋白水平、淋巴细胞和血小板计数等广泛免疫营养指标的分化潜力。本研究的目的是探讨治疗前小野村的预后营养指数(OPNI)、crp -白蛋白淋巴细胞(CALLY)指数和血红蛋白、白蛋白、淋巴细胞和血小板(HALP)评分是否因乳腺癌特征而异。我们共招募了135名连续新诊断的乳腺癌患者,这些患者未接受尼日利亚伊巴丹大学学院医院放射肿瘤科的任何治疗。采用自动分析仪测定淋巴细胞计数、血小板计数和血红蛋白水平,ELISA法测定血清CRP和白蛋白水平。计算免疫营养指数(OPNI、CALLY、HALP)。与对照组相比,乳腺癌患者血红蛋白浓度、血清白蛋白水平、OPNI、CALLY、HALP显著降低,血清CRP显著升高。与早期乳腺癌患者相比,晚期乳腺癌患者的OPNI、CALLY和HALP的平均值显著降低,而低分化和转移性乳腺癌患者的CALLY分别与分化良好和非转移性乳腺癌患者相比显著降低。这项研究证实了乳腺癌患者存在营养不良和炎症,尤其是晚期、低分化和转移性乳腺癌患者。这就要求监测所有乳腺癌患者的肝功能。
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引用次数: 0
Performance in tuna and other fishery resources use in southwestern Côte d’Ivoire: a case study stating implications for fishers´ settlement and employment generated by the marine artisanal fishing sector 在Cô´科特迪瓦西南部使用金枪鱼和其他渔业资源的绩效:一个案例研究,说明海洋手工捕鱼部门对fishers´´定居和就业的影响
Pub Date : 2022-08-27 DOI: 10.14419/ijbas.v11i2.32078
Laurent Bahou, Benié AbouaAtsé Boua, Célestin Rose Danielle, Tidiani Koné
Gathered facts about the marine artisanal fishery located at Sassandra, southwestern Côte d’Ivoire are provided, talking about commercial species that are targeted by that fishery, addressing the types of jobs generated and stating the prominent role of women, especially that of fishers´ wives, in post-harvesting tasks and related activities. Therefore, interviews were carried out in February, March and July 2021, within the fishers´ community, at dockside and marketplaces. The results indicated that the fishing sector generated a large number of professionals (250 respondents, of whom 76 men and 174 women) who were associated with fifteen types of jobs listed among managers appointed by the Government and privately employed professionals. In addition, socio-economic characteristics that were focused on indicated that the highest percentage of active persons (38.4%) was recorded within the age bracket of 35-45. More than half of respondents had no schooling. Tunas and other species landed, depending on fishing seasons, made up a large part of the fish consumed. Daily fish-consumption varied depending on household numbers, with consumption between 1.0 and 1.5 Kg/d or 2.0 and 2.5 Kg/d being the commonest. This study really shows that the local fishery is of vital importance to the whole community.   
本文提供了收集到的关于位于Cô´科特迪瓦西南部Sassandra的海洋手工渔业的事实,讨论了该渔业所针对的商业物种,解决了所产生的工作类型,并说明了妇女,特别是fishers´´妻子在捕捞后任务和相关活动中的突出作用。因此,我们于2021年2月、3月和7月在fishersÂ社区、码头和市场进行了访谈。结果表明,渔业部门培养了大量的专业人员(250名答复者,其中76名男子和174名妇女),他们从事政府任命的管理人员和私人雇用的专业人员所列的15种工作。此外,重点关注的社会经济特征表明,35-45岁年龄组的活跃人口比例最高(38.4%)。超过一半的受访者没有上过学。金枪鱼和其他鱼类的上岸,取决于捕鱼季节,占鱼类消费的很大一部分。每日鱼类食用量因住户人数而异,最常见的食用量为每日1.0至1.5公斤或每日2.0至2.5公斤。这项研究确实表明,当地渔业对整个社区至关重要。  Â
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引用次数: 0
Modeling of dielectric permittivity in the aggregation of erythrocyte molecules: application to deoxy-hemoglobin S 红细胞分子聚集过程中介电常数的建模:脱氧血红蛋白S的应用
Pub Date : 2022-08-27 DOI: 10.14419/ijbas.v11i2.31965
Olawolé W. Akadry, Adébayo L. Essoun, A. Adomou, S. Massou
In this paper, study of the impact of a new treatment approach in the aggregation kinetics of deoxy-hemoglobin S molecules is developed. New approach exploring mathematical model of dielectric permittivity of Davidson-Cole and takes into account several relaxation times of the dielectrics substances like blood. Results are such that, (i) only a fine analysis of intrinsic energy dissipation curves allow sufficient precision to be obtained to describe chronic hemolytic anemia due to sickle cell anemia based on the frequency of relaxation, (ii) hematocrit calculation by the formula allowed to show the uniqueness of the relaxation time of deoxy-hemoglobin S, (iii) hematocrit levels are low and the dispersion coefficient is the parameter most influential in the aggregation of hemoglobin S. From the analysis of all these results, it appears that, the mathematical model of Davidson-Cole is a good model interpretation and knowledge of sickle cell disease. The interest of this work is the understanding of the molecular mechanism that can help develop new treatment approaches capable of preventing or limiting the risk of complications of red blood cell diseases.  
本文研究了一种新的处理方法对脱氧血红蛋白S分子聚集动力学的影响。提出了一种探索戴维森-科尔介电常数数学模型的新方法,并考虑了血液等介电物质的几种弛豫时间。结果表明,(i)只有对固有能量耗散曲线进行精细分析,才能获得足够的精度来描述基于松弛频率的镰状细胞性贫血引起的慢性溶血性贫血;(ii)用公式计算红细胞压积,以显示缺氧血红蛋白S松弛时间的唯一性。(iii)红细胞压积水平低,弥散系数是影响血红蛋白s聚集的最重要的参数。从这些结果的分析来看,Davidson-Cole的数学模型是一个很好的模型解释和对镰状细胞病的认识。这项工作的兴趣是了解分子机制,可以帮助开发新的治疗方法,能够预防或限制红细胞疾病并发症的风险。一个一个
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引用次数: 0
Study and design of a coconut stripper 椰子脱粒机的研究与设计
Pub Date : 2022-07-17 DOI: 10.14419/ijbas.v11i2.32071
Edmond Claude Vodounnou, Guy Clarence Semassou, Roger H. Ahouansou
The predominance of the primary sector is noticeable in the economy of most African countries, particularly in Benin. Thus, to make this sector a vector of wealth and development, it is imperative to think about the development of technologies to improve the efficiency of processing and product quality. The mechanization of this sector is therefore necessary to make it more competitive. In Benin we have a lot of products which are made with the coconut. This sector has been relegated to a non-priority plan, whereas the coconut palm is a plant with a very considerable value like the oil palm, of which all the derived products are usable. It seems necessary to pass to the revival of this sector to help to stabilize the incomes of the small producers and traders in particular and to improve the commercial balance of the country in general. The maximization of the output of this sector directs towards the formula of Lavoisier: "nothing is lost, nothing is created, everything is transformed". The application of this formula allows us to transform the by-products of the said product. Currently, the de-shearing of the coconut is done manually with a cutter or with a pointed object. This way of making is too painful for producers who have large exploitations of coconut trees. In order to make this sector more profitable, our end-of-training work focuses on the study and design of a coconut de-sheathing machine intended to accompany coconut producers by reducing their pains and increasing their productivity in order to enhance the transformation of the said product.  
在大多数非洲国家,特别是贝宁的经济中,初级部门的主导地位是显而易见的。因此,为了使这一部门成为财富和发展的载体,必须考虑发展技术,以提高加工效率和产品质量。因此,为了使这个部门更具竞争力,机械化是必要的。在贝宁,我们有很多用椰子做的产品。该部门已被降级为非优先计划,而椰子树是一种像油棕一样具有非常可观价值的植物,其所有衍生产品都是可用的。似乎有必要恢复这一部门,以帮助稳定特别是小生产者和贸易商的收入,并改善该国的一般商业平衡。这个部门的产出最大化指向拉瓦锡的公式:“没有什么损失,没有什么创造,一切都在改变”。应用这个公式,我们可以变换上述产物的副产物。目前,椰子的去剪切是用刀具或尖物体手动完成的。这种制作方式对拥有大量椰子树的生产者来说太痛苦了。为了使这一行业更有利可图,我们的培训结束后的工作重点是研究和设计一种椰子脱皮机,旨在帮助椰子生产者减少他们的痛苦,提高他们的生产力,以促进上述产品的转型。一个一个
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引用次数: 0
Behavior of the epidemic due to the covid-19 virus in Mexico. Development of an algorithm 由于covid-19病毒在墨西哥的流行行为。算法的开发
Pub Date : 2022-05-15 DOI: 10.14419/ijbas.v11i1.32013
Yael A. Almaguer-Salinas, D. Ladino-Luna, Ricardo T. Paez-Hernández
In the present paper, an algorithm was developed to represent the behavior of the current SARS-CoV-2 virus epidemic in Mexico, known as COVID-19, to obtain a likely scenario for the coming months and provoke a healthy discussion about the problem. The data reported by government entities is considered first by analyzing a simple model, via the construction of a polynomial, and then building an exponential type function, from the so-called logistic function. A numerical comparison is made with the officially provided data, and the graphs obtained from the solutions found are shown, including a brief explanation on how to interpret them appropriately. Finally, the possible scenario for the following months of the development of the epidemic in Mexico is discussed.  
在本文中,开发了一种算法来表示墨西哥当前的SARS-CoV-2病毒流行(称为COVID-19)的行为,以获得未来几个月的可能情景,并引发有关该问题的健康讨论。政府实体报告的数据首先通过分析一个简单的模型来考虑,通过构造一个多项式,然后从所谓的逻辑函数中构建一个指数型函数。与官方提供的数据进行了数值比较,并显示了从所找到的解中得到的图形,包括如何正确解释它们的简要说明。最后,讨论了今后几个月墨西哥疫情发展的可能情况。一个一个
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引用次数: 0
Principal centrality measures: a comprehensive approach to the Spanish stocks market 主要中心性措施:西班牙股市的综合方法
Pub Date : 2022-04-16 DOI: 10.14419/ijbas.v11i1.31992
Amauri Gutierrez
In social network analysis, for determining the relevance or significance of a node in the network, several node centrality measures are often used such as degree centrality, betwenness centrality, closeness centrality, eigenvector, subgraph and page rank centrality. In this paper we apply a principal components analysis over the traditional centrality measures for obtaining an overall single metric that combines the best attributes of the traditional centrality measures and permits to detect relevant nodes in the network. Concretely, a detailed study of the Spanish stocks market will be used for demonstrating the advantages of this approach.
在社会网络分析中,为了确定网络中一个节点的相关性或重要性,通常使用几个节点中心性度量,如度中心性、间中心性、接近中心性、特征向量、子图和页面排名中心性。在本文中,我们对传统的中心性度量应用主成分分析来获得一个整体的单一度量,该度量结合了传统中心性度量的最佳属性,并允许检测网络中的相关节点。具体而言,将通过对西班牙股票市场的详细研究来证明这种方法的优势。
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引用次数: 0
Soliton-like solutions of nonlinear scalar and electromagnetic field equations in gravitational theory 引力理论中非线性标量和电磁场方程的类孤子解
Pub Date : 2022-04-04 DOI: 10.14419/ijbas.v11i1.31994
YAMADJAKO Arnaud Edouard, A. Adomou, A. Houngan
In this work, exact analytical static spherical symmetric solutions to the nonlinear interacting electromagnetic and massless scalar field equations have been determined taking into account the proper gravitational field of elementary particles. The obtained results prove that all solutions of the Einstein equation and those of the interacting fields are regular with localized energy density. All non-zero components of the 4-vector potential are solutions to the inverted Painlevé-Gambier XI equation. Moreover, the total energy of interacting fields is limited and the total charge of elementary particles is finite. These solutions obtained are soliton-like and can be used as a model to describe the internal structure of elementary particles.
在考虑基本粒子固有引力场的情况下,确定了非线性相互作用电磁和无质量标量场方程的精确解析静态球对称解。所得结果证明了爱因斯坦方程的所有解和相互作用场的解都具有局域能量密度的正则性。此外,相互作用场的总能量是有限的,基本粒子的总电荷是有限的。这些解是类孤子解,可以作为描述基本粒子内部结构的模型。
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引用次数: 0
Exact static spherical symmetric soliton-like solutions to the scalar and electromagnetic nonlinear induction field equations in general relativity 广义相对论中标量和电磁非线性感应场方程的精确静态球对称类孤子解
Pub Date : 2021-12-16 DOI: 10.14419/ijbas.v10i2.31747
A. Adomou, YAMADJAKO Arnaud Edouard, Y. Kpomahou, J. Edou, S. Massou
In this paper, we have obtained exact static spherical symmetric soliton-like solutions to the electromagnetic and scalar nonlinear induction field equations taking into account the own gravitational field of the elementary. The results show that the metric tensor functions are regular with localized energy density. Moreover, the total energy of the nonlinear induction fields is bounded and the total charge of elementary particles has a finite value. The importance of the own gravitational field of elementary particles and the role of the nonlinearity of fields in the determination of these solutions have been proved.
本文给出了考虑初等引力场的电磁和标量非线性感应场方程的精确静态球对称类孤子解。结果表明,度量张量函数具有局域化能量密度的正则性。此外,非线性感应场的总能量是有界的,基本粒子的总电荷是有限的。证明了基本粒子自身引力场的重要性和引力场的非线性在确定这些解中的作用。
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引用次数: 1
Assessing the impacts of inter-annual rainfall variability on cash crops’ yield in Ondo state, Nigeria 评估尼日利亚Ondo州年际降雨量变化对经济作物产量的影响
Pub Date : 2021-11-19 DOI: 10.14419/ijbas.v10i2.31749
Omosuyi Oluwayemisi Bukola, Akinfisoye Emmanuel Oluwadunsin, Funmilayo Olukemi Abimbola
The agriculture sector is of great importance to the development of any nation in Africa; hence, it is determined by the operating climatic mechanisms of such nation, especially rainfall. This study was carried out to assess the inter-annual rainfall variability impacts on cash crop yield in Ondo state for a period of twenty years (2000-2019). The study employed mainly secondary data which was analyzed using inferential statistics. Trend analysis was used to determine the pattern of rainfall and cash crops’ yield for the period under review. Also it was revealed that there were fluctuations in the trend of rainfall and the yield of cash crops. The correlation analysis showed a significant relationship between rainfall and cash crops yield; but an inverse relationship with rubber yield specifically. On the other hand the regression analysis showed little impact of rainfall variability on cash crop yield. However, it was recommended that in this era of dwindling economy due to over reliance on crude oil in Nigeria, the government through National Orientation Agency and Non-governmental Organizations should keep persuading and enlightening Nigerians to venture into agriculture to save the country’s economy and reduce poverty.  
农业部门对非洲任何国家的发展都非常重要;因此,它是由这个国家的运行气候机制决定的,特别是降雨。本研究旨在评估为期20年(2000-2019年)的Ondo州年际降雨变率对经济作物产量的影响。本研究主要采用二手资料,采用推理统计方法进行分析。趋势分析用于确定本报告所述期间的降雨模式和经济作物€™产量。降雨趋势和经济作物产量也存在波动。相关分析表明,降雨量与经济作物产量呈显著相关;但与橡胶产量呈反比关系。另一方面,回归分析显示降雨变率对经济作物产量的影响不大。然而,有人建议,在尼日利亚由于过度依赖原油而导致经济萎缩的时代,政府应该通过国家定向机构和非政府组织继续说服和启发尼日利亚人冒险进入农业,以拯救国家的经济并减少贫困。一个一个
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引用次数: 0
Numerical analysis of stochastic processes in the aggregation erythrocyte molecules : Application to deoxy-hemoglobin S 红细胞分子聚集随机过程的数值分析:在脱氧血红蛋白中的应用
Pub Date : 2021-11-19 DOI: 10.14419/ijbas.v10i2.31755
Olawolé O. Akadry, Adébayo L. Essoun, A. Noumon, S. Massou
Previously, by analytical method, some authors have shown that the harmonic noise is more indicated in the aggregation of deoxy-hemoglobin S. The problem that still arises is the relationship between the energy spectra and the microscopic properties of dielectric substances. The numerical approach of the correlation function’s Fourier transform of different random processes have permit to obtain the frequency distribution spectra of energy and the fluctuations of the amplitudes. The results have shown that (i) only a fine analysis of the curves can permit obtain sufficient precision on the noise indicated in the aggregation of deoxy-hemoglobin S, (ii) in the presence of harmonic noise, the frequency distribution of energy and fluctuations of the amplitudes are low compared to white and colored noise, (iii) method exploiting the frequency distribution of energy and the fluctuations of the amplitudes justify well that the harmonic noise is the best indicated in the aggregation of the deoxy-hemoglobin S.  
在此之前,一些作者已经用解析的方法证明了在脱氧血红蛋白s的聚集过程中谐波噪声更明显,但仍存在的问题是介电物质的能谱与微观性质之间的关系。不同随机过程的相关函数的傅里叶变换的数值方法可以得到能量的频率分布谱和振幅的波动。结果表明:(1)只有对曲线进行精细分析,才能对脱氧血红蛋白S聚集所显示的噪声获得足够的精度;(2)与白噪声和有色噪声相比,谐波噪声存在时,能量的频率分布和振幅的波动较低。(三)利用能量的频率分布和振幅波动的方法很好地证明,谐波噪声在脱氧血红蛋白的聚集中表现得最好S. Â
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引用次数: 0
期刊
International Journal of Sciences: Basic and Applied Research
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