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Association Between Ultra-Processed Food Consumption and Cognitive Performance Among Adolescent Students From Underdeveloped Cities in Brazil: A Cross-Sectional Study. 巴西欠发达城市青少年学生超加工食品摄入量与认知能力之间的关系:一项横断面研究
IF 2.6 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-08 eCollection Date: 2024-01-01 DOI: 10.3389/ijph.2024.1607658
João Victor Laurindo Dos Santos, Ingrid Sofia Vieira de Melo, Clara Andrezza Crisóstomo Bezerra Costa, Layanne Cabral de Almeida, Dafiny Rodrigues Silva, Débora Cavalcante Ferro, Déborah Tenório Costa Paula, Mateus de Lima Macena, Nassib Bezerra Bueno

Objectives: The association between ultra-processed foods (UPF) consumption and cognitive performance needs to be better characterized in adolescents, especially in low-income settings, where the cost of human capital is high. This study investigated the association between cognitive performance and UPF in adolescents from the countryside of the Brazilian Northeast.

Methods: Adolescents (15-18 years old) from three public high schools were included. Food intake was assessed using three 24-hour dietary recalls. The classification of foods as UPF was determined according to the Nova classification. Cognitive performance was evaluated using the Non-Verbal General Intelligence Test.

Results: 116 adolescents were included, of which 50 (43.1%) showed low cognitive performance. The average energy intake was 1973.5 kcal, with 24.2% coming from UPF. Participants with low cognitive performance consumed 26.5% (95% CI: [22.2; 30.7]%) of daily energy intake from UPF compared to 22.5% ([18.8; 26.2]%) of those with medium-high cognitive performance (P = 0.17), without differences in energy and macronutrient intake.

Conclusion: Despite similar UPF consumption compared to the Brazilian average, no association was found between UPF consumption and cognitive performance in this low-income adolescent sample.

研究目的需要更好地了解青少年食用超加工食品(UPF)与认知能力之间的关系,尤其是在人力资本成本较高的低收入环境中。本研究调查了巴西东北部农村青少年的认知能力与超加工食品之间的关系:研究对象包括来自三所公立高中的青少年(15-18 岁)。食物摄入量通过三次 24 小时饮食回忆进行评估。根据诺瓦分类法确定食物的 UPF 分类。认知能力采用非言语综合智力测验进行评估:结果:共纳入 116 名青少年,其中 50 人(43.1%)认知能力低下。平均能量摄入量为 1973.5 千卡,其中 24.2% 来自 UPF。认知能力低的参与者每天摄入的能量中有26.5%(95% CI:[22.2;30.7]%)来自UPF,而认知能力中等偏上的参与者每天摄入的能量中有22.5%([18.8;26.2]%)来自UPF(P = 0.17),两者在能量和宏量营养素摄入方面没有差异:结论:尽管UPF摄入量与巴西的平均水平相近,但在这一低收入青少年样本中,UPF摄入量与认知能力之间没有关联。
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引用次数: 0
Beyond the Horizon: Switzerland's Quest for EU Research Framework Re-Integration. 超越地平线:瑞士对欧盟研究框架重新整合的探索。
IF 2.6 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-07 eCollection Date: 2024-01-01 DOI: 10.3389/ijph.2024.1607839
Hania Janta, Michael Käser
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引用次数: 0
Risk, Attributable Fraction and Attributable Number of Cause-Specific Heat-Related Emergency Hospital Admissions in Switzerland. 瑞士与高温有关的急诊入院人数的风险、可归因比例和可归因人数。
IF 2.6 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-07 eCollection Date: 2024-01-01 DOI: 10.3389/ijph.2024.1607349
Florian Schulte, Martin Röösli, Martina S Ragettli

Objectives: We assessed the relationship between heat and emergency hospital admissions (EHAs) in Switzerland using clinically relevant metrics.

Methods: Applying distributed lag non-linear models, we investigated temperature-admission associations between May and September 1998-2019 for various disease groups, by age class and gender. We estimated the relative risk (RR) for moderate (29°C) and extreme (34°C) daily maximum temperatures relative to disease-specific optimum temperature, and calculated attributable fractions (AFs) for hot days and the following week. We also calculated the total number of heat-related EHAs.

Results: We attributed 31,387 (95% confidence interval: 21,567-40,408) EHAs to above-optimal temperatures, 1.1% (0.7%-1.4%) of the total. Extreme temperatures increased the EHA risk for mental, infectious and neurological diseases. We observed particularly high AFs due to extreme heat for dehydration (85.9%, 95% CI: 82.4%-88.8%) and acute kidney injury (AKI, 56.1%, 95% CI: 45.3%-64.7%). While EHA risk generally increased with age, we also found high RRs for infectious diseases in children (0-15 years) and AKI in young adults (15-64 years).

Conclusion: Hot weather increases the EHA risk in Switzerland. Therefore a comprehensive clinical and public health response is needed.

目的:我们使用临床相关指标评估了瑞士高温与急诊入院率(EHA)之间的关系:我们使用临床相关指标评估了瑞士高温与急诊入院率(EHA)之间的关系:采用分布式滞后非线性模型,我们调查了 1998 年 5 月至 2019 年 9 月期间不同疾病组、不同年龄段和不同性别的气温与入院率之间的关系。我们估算了中度(29°C)和极端(34°C)日最高气温相对于疾病特定最适温度的相对风险(RR),并计算了高温日和随后一周的可归因分数(AF)。我们还计算了与高温相关的 EHA 总次数:我们将 31,387 例(95% 置信区间:21,567-40,408)EHA 归因于高于最佳温度,占总数的 1.1%(0.7%-1.4%)。极端气温增加了精神疾病、传染病和神经系统疾病的 EHA 风险。我们观察到,极端高温导致脱水(85.9%,95% CI:82.4%-88.8%)和急性肾损伤(AKI,56.1%,95% CI:45.3%-64.7%)的 AFs 特别高。虽然EHA风险一般随年龄增长而增加,但我们也发现儿童(0-15岁)感染传染病和年轻成人(15-64岁)急性肾损伤的RR较高:结论:炎热的天气增加了瑞士的 EHA 风险。因此,需要采取全面的临床和公共卫生应对措施。
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引用次数: 0
Association Between Disability and Suicide Mortality in the Spanish Community-Dwelling Adult Population. A Population-Based Follow-Up Study. 西班牙社区成年居民中残疾与自杀死亡率之间的关系。基于人口的跟踪研究。
IF 2.6 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-07 eCollection Date: 2024-01-01 DOI: 10.3389/ijph.2024.1607344
Roberto Pastor-Barriuso, Alicia Padrón-Monedero, Javier Almazán-Isla, Fernando J García López, Jesús de Pedro-Cuesta, Javier Damián

Objectives: To assess the association of disability with suicide mortality, separately for women and men by age group.

Methods: Information was obtained from a representative national sample of 161,809 community-dwelling adults (≥18 years). Participants contributed to follow-up time from baseline interview (2008) until suicide, death by other causes, or 2017. We calculated, by sex, standardized suicide mortality differences (SSMD), comparing persons with and without disabilities standardized to sociodemographic distribution of disability population.

Results: 29 women died by suicide during 800,754 person-years follow-up and 97 men during 735,709 person-years. Among women with disabilities, SSMD (95% Confidence interval) per 100,000 person-years at 5 years was 54.4 deaths (-17.2 to 126.1) [100.0 (-27.4 to 227.4) in women <65 years and -4.8 (-27.3 to 17.7) in women ≥65 years (P homogeneity = 0.11)]. Among men, SSMD increased by 122.2 deaths (4.1 to 240.3) [37.2 (-40.2 to 114.6) in men <65 years and 74.7 (-51.8 to 200.5) in men ≥65 years (P homogeneity = 0.62)].

Conclusion: Suicide risk was higher in women and men with disability. In women higher risk was only notable for those <65. Men presented similar effects in both age groups. Nevertheless, due to imprecision of estimates, results should be viewed cautiously.

目标:按年龄组分别评估残疾与自杀死亡率的关系:按年龄组分别评估女性和男性残疾与自杀死亡率的关系:从 161 809 名居住在社区的成年人(≥18 岁)的代表性全国样本中获取信息。参与者提供了从基线访谈(2008 年)到自杀、因其他原因死亡或 2017 年的随访时间。我们按性别计算了标准化自杀死亡率差异(SSMD),并根据残疾人口的社会人口分布情况对有残疾和无残疾者进行了标准化比较。在残疾女性中,5 年后每 10 万人年的 SSMD(95% 置信区间)为 54.4 例死亡(-17.2 至 126.1)[女性为 100.0 例(-27.4 至 227.4)]:残疾女性和男性的自杀风险较高。在女性中,只有下列人群的自杀风险较高
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引用次数: 0
Precision Epidemiology: A Computational Analysis of the Impact of Algorithmic Prediction on the Relationship Between Population Epidemiology and Clinical Epidemiology. 精准流行病学:算法预测对人群流行病学与临床流行病学之间关系影响的计算分析》(A Computational Analysis of the Impact of Algorithmic Prediction on the Relationship Between Population Epidemiology and Clinical Epidemiology)。
IF 2.6 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-01 eCollection Date: 2024-01-01 DOI: 10.3389/ijph.2024.1607396
Elena Esposito, Paola Angelini, Sebastian Schneider

Objectives: Precision Medicine (PM) uses advanced Machine Learning (ML) techniques and big data to develop personalized treatments, but healthcare still relies on traditional statistical procedures not targeted on individuals. This study investigates the impact of ML on epidemiology.

Methods: A quantitative analysis of the articles in PubMed for the years 2000-2019 was conducted to investigate the use of statistical methods and ML in epidemiology. Using structural topic modelling, two groups of topics were identified and analysed over time: topics closer to the clinical side of epidemiology and topics closer to the population side.

Results: The curve of the prevalence of topics associated with population epidemiology basically corresponds to the curve of the relative statistical methods, while the more dynamic curve of clinical epidemiology broadly reproduces the trend of algorithmic methods.

Conclusion: The findings suggest that a renewed separation between clinical epidemiology and population epidemiology is emerging, with clinical epidemiology taking more advantage of recent developments in algorithmic techniques and moving closer to bioinformatics, whereas population epidemiology seems to be slower in this innovation.

目标:精准医学(PM)利用先进的机器学习(ML)技术和大数据来开发个性化治疗方法,但医疗保健仍依赖于传统的统计程序,而不是针对个人。本研究调查了 ML 对流行病学的影响:对2000-2019年PubMed上的文章进行了定量分析,以调查统计方法和ML在流行病学中的应用。通过结构主题建模,确定了两组主题,并随时间推移进行了分析:更接近流行病学临床方面的主题和更接近人群方面的主题:结果:与人群流行病学相关的主题流行率曲线基本上与相对统计方法的曲线一致,而临床流行病学的动态曲线则大致再现了算法方法的趋势:研究结果表明,临床流行病学和人群流行病学之间正在重新分离,临床流行病学更多地利用算法技术的最新发展,并向生物信息学靠拢,而人群流行病学在这一创新方面似乎较为缓慢。
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引用次数: 0
Predictors of Overweight/Obesity Among Preschool Children in Arba Minch City, Southern Ethiopia: Does Consumption of Sweet Food Predispose to Overweight/Obesity? 埃塞俄比亚南部阿尔巴明奇市学龄前儿童超重/肥胖的预测因素:食用甜食会导致超重/肥胖吗?
IF 2.6 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-01 eCollection Date: 2024-01-01 DOI: 10.3389/ijph.2024.1607017
Simegn Wagaye Kefene, Tamirat Gezahegn Guyo, Darik Temesgen Assefa, Yilma Chisha, Muluken Bekele Sorrie

Objectives: Childhood overweight/obesity is a serious public health problem in the world today specially low-and-middle income countries like Ethiopia. This study aimed to assess the prevalence of overweight/obesity and associated factors among preschool children.

Methods: A community-based cross-sectional study was conducted among preschool children aged 3-5 years in Arba Minch city from April to June 2022. A multistage sampling method was used to select 577 study participants. Data were collected using a structured and pretested questionnaire. A binary logistic regression model was used for analysis. An adjusted odds ratio (AOR) with a 95% confidence interval (CI) was used to assess the strength of the association.

Results: The combined prevalence of overweight/obesity was 23.9% (95% CI: 20.5, 27.6). Age of 36-47 months, family size < five, watching TV/video for ≥2 h, and consuming sweet foods, were factors associated with being overweight/obese among preschool children.

Conclusion: Overweight/obesity was predicted by consuming sweet foods, long time TV/video watching, and large family size in the study area. Special attention should be given to child feeding practices and reducing sedentary lifestyles.

目的:儿童超重/肥胖症是当今世界一个严重的公共卫生问题,尤其是像埃塞俄比亚这样的中低收入国家。本研究旨在评估学龄前儿童超重/肥胖的发生率及相关因素:方法:2022 年 4 月至 6 月,在阿尔巴明奇市 3-5 岁学龄前儿童中开展了一项基于社区的横断面研究。采用多阶段抽样方法选出了 577 名研究参与者。数据收集采用结构化的预试问卷。采用二元逻辑回归模型进行分析。采用调整后的几率比(AOR)和 95% 的置信区间(CI)来评估相关性的强度:超重/肥胖的综合发生率为 23.9%(95% CI:20.5,27.6)。年龄为 36-47 个月、家庭人口<5 人、看电视/视频时间≥2 小时以及食用甜食是学龄前儿童超重/肥胖的相关因素:结论:在研究地区,食用甜食、长时间看电视/视频和家庭人口多都会导致儿童超重/肥胖。应特别关注儿童喂养方式和减少久坐不动的生活方式。
{"title":"Predictors of Overweight/Obesity Among Preschool Children in Arba Minch City, Southern Ethiopia: Does Consumption of Sweet Food Predispose to Overweight/Obesity?","authors":"Simegn Wagaye Kefene, Tamirat Gezahegn Guyo, Darik Temesgen Assefa, Yilma Chisha, Muluken Bekele Sorrie","doi":"10.3389/ijph.2024.1607017","DOIUrl":"https://doi.org/10.3389/ijph.2024.1607017","url":null,"abstract":"<p><strong>Objectives: </strong>Childhood overweight/obesity is a serious public health problem in the world today specially low-and-middle income countries like Ethiopia. This study aimed to assess the prevalence of overweight/obesity and associated factors among preschool children.</p><p><strong>Methods: </strong>A community-based cross-sectional study was conducted among preschool children aged 3-5 years in Arba Minch city from April to June 2022. A multistage sampling method was used to select 577 study participants. Data were collected using a structured and pretested questionnaire. A binary logistic regression model was used for analysis. An adjusted odds ratio (AOR) with a 95% confidence interval (CI) was used to assess the strength of the association.</p><p><strong>Results: </strong>The combined prevalence of overweight/obesity was 23.9% (95% CI: 20.5, 27.6). Age of 36-47 months, family size < five, watching TV/video for ≥2 h, and consuming sweet foods, were factors associated with being overweight/obese among preschool children.</p><p><strong>Conclusion: </strong>Overweight/obesity was predicted by consuming sweet foods, long time TV/video watching, and large family size in the study area. Special attention should be given to child feeding practices and reducing sedentary lifestyles.</p>","PeriodicalId":14322,"journal":{"name":"International Journal of Public Health","volume":"69 ","pages":"1607017"},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11473308/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142465471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of Unmet Healthcare Needs on the Perceived Health Status of Older Europeans During COVID-19. 在 COVID-19 期间,未满足的医疗保健需求对欧洲老年人感知健康状况的影响。
IF 2.6 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-30 eCollection Date: 2024-01-01 DOI: 10.3389/ijph.2024.1607336
Šime Smolić, Nikola Blaževski, Margareta Fabijančić

Objectives: To examine how unmet healthcare needs and the exposure to the pandemic impacted self-reported health (SRH) among individuals aged 50 and above.

Methods: We use data from two waves of the Survey of Health, Ageing and Retirement in Europe (SHARE) Corona Survey collected in 2020 and 2021 in 27 European countries and Israel (N = 42,854). Three dimensions of barriers to healthcare access were investigated: healthcare forgone, postponed, and denied. Mixed-effects logistic regression analysis was employed to explore SRH deterioration during the pandemic.

Results: Findings indicate that unmet healthcare needs decreased throughout the pandemic but significantly contributed to the worsening of SRH among older adults. Mild or severe exposure to the pandemic heightened the likelihood of reporting deteriorated SRH. Additionally, the pandemic disproportionately affected females, the oldest-old, and those living alone or facing economic vulnerability.

Conclusion: To mitigate the adverse effects on the health status of older adults, policymakers are strongly advised to prioritize addressing the healthcare needs of those who have been disproportionately affected by the pandemic.

目的研究未满足的医疗保健需求和大流行对 50 岁及以上人群自我健康报告(SRH)的影响:我们使用了 2020 年和 2021 年在 27 个欧洲国家和以色列收集的两次欧洲健康、老龄和退休调查(SHARE)Corona 调查的数据(N = 42854)。调查从三个方面探讨了获得医疗保健的障碍:放弃、推迟和拒绝医疗保健。采用混合效应逻辑回归分析来探讨大流行期间性健康和生殖健康状况的恶化:研究结果表明,在整个大流行期间,未得到满足的医疗保健需求有所减少,但在很大程度上导致了老年人性健康和生殖健康状况的恶化。轻度或严重的大流行会增加报告性健康和生殖健康状况恶化的可能性。此外,大流行对女性、最年长者、独居者或经济脆弱者的影响尤为严重:为减轻对老年人健康状况的不利影响,强烈建议政策制定者优先满足受大流行病影响过大的人群的医疗保健需求。
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引用次数: 0
Long-Term Exposure to Particulate Matter and Mortality: An Update of the WHO Global Air Quality Guidelines Systematic Review and Meta-Analysis. 长期暴露于微粒物质与死亡率:世界卫生组织全球空气质量指南的系统回顾和元分析更新》。
IF 2.6 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-27 eCollection Date: 2024-01-01 DOI: 10.3389/ijph.2024.1607683
Pablo Orellano, Maria-Iosifina Kasdagli, Román Pérez Velasco, Evangelia Samoli

Objectives: For the development of the 2021 global air quality guidelines, the World Health Organization (WHO) commissioned a series of systematic reviews and meta-analyses to assess the association between exposure to air pollution and all-cause and cause-specific mortality. One of these reviews, which we aim to update, focused on the effects of long-term exposure to PM2.5 and PM10 on all-cause and cause-specific mortality.

Methods: The protocol for this study was registered in PROSPERO (CRD42023425327). We searched the PubMed and Embase databases for studies published between September 2018 and May 2023. Study-specific effects were pooled using random-effects models.

Results: We included 106 studies in the meta-analysis, 46 studies from the previous review and 60 from this update. All exposure-outcome pairs analysed showed positive and significant associations, except for PM10 and cerebrovascular mortality. The certainty of the evidence was rated as high for the majority of exposure-outcome pairs.

Conclusion: We included a large number of new cohorts, and provided new concentration-response functions that will inform WHO advice on the use of this information for air pollution health risk assessments.

目标:为制定 2021 年全球空气质量指南,世界卫生组织(WHO)委托开展了一系列系统综述和荟萃分析,以评估空气污染暴露与全因和特定原因死亡率之间的关系。我们旨在更新其中的一篇综述,重点关注长期暴露于PM2.5和PM10对全因和特定原因死亡率的影响:本研究的方案已在 PROSPERO(CRD42023425327)上注册。我们在 PubMed 和 Embase 数据库中检索了 2018 年 9 月至 2023 年 5 月间发表的研究。采用随机效应模型对研究的特异性效应进行了汇总:我们在荟萃分析中纳入了 106 项研究,其中 46 项来自之前的综述,60 项来自本次更新。除了 PM10 与脑血管死亡率的关系外,所有分析的暴露-结果对都显示出积极和显著的关联。大多数暴露-结果对的证据确定性都被评为 "高":我们纳入了大量新的队列,并提供了新的浓度-反应函数,这将为世界卫生组织在空气污染健康风险评估中使用这些信息提供参考。
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引用次数: 0
Associations of Lifestyle, Ambient Air Pollution With Progression of Asthma in Adults: A Comprehensive Analysis of UK Biobank Cohort. 生活方式、环境空气污染与成人哮喘进展的关系:英国生物库队列综合分析》。
IF 2.6 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-25 eCollection Date: 2024-01-01 DOI: 10.3389/ijph.2024.1607640
Jialu He, Jiahui Wu, Yinan He, Dequan Shen, Xianglong Huang, Xinmeng Yao, Weihong Tang, Guo-Bo Chen, Chengyin Ye

Objectives: We aim to investigate the associations between lifestyle, ambient air pollution with crucial outcomes in the progression of adult asthma, including asthma new-onset and asthma hospitalisation.

Methods: 176,800 participants were included to assess the prospective association between baseline risk exposures and the subsequent asthma onset, 17,387 participants were used to evaluate asthma hospitalisation. Cox regression models were employed to examine the associations.

Results: In terms of lifestyle factors, the HRs (95% CIs) of the least healthy lifestyle categories for asthma incidence and hospitalization were 1.099 (1.017-1.187) and 1.064 (1.008-1.123), respectively. For pollutants, PM2.5, especially the traffic-related PM2.5 component, was consistently recognized as a significant risk factor for asthma onset (HR = 1.064, 95% CI: 1.034-1.094) and hospitalisation (HR = 1.031, 95% CI: 1.010-1.052) under various model adjustments. Low socioeconomic status also played a major role in the progression of adult asthma.

Conclusion: Our study provides crucial insights into factors influencing the progression of adult asthma. Monitoring and reducing exposure to air pollution, particularly PM2.5, promoting healthier lifestyle, and addressing socioeconomic inequity are important in preventing and managing asthma.

目的:我们旨在研究生活方式、环境空气污染与成人哮喘发展过程中的重要结果(包括哮喘新发和哮喘住院)之间的关系:我们旨在研究生活方式、环境空气污染与成人哮喘发展过程中的重要结果(包括哮喘新发和哮喘住院)之间的关联。方法:纳入 176800 名参与者,评估基线风险暴露与后续哮喘发病之间的前瞻性关联;纳入 17387 名参与者,评估哮喘住院情况。研究采用 Cox 回归模型来检验两者之间的关联:在生活方式因素方面,最不健康的生活方式类别对哮喘发病率和住院率的HRs(95% CIs)分别为1.099(1.017-1.187)和1.064(1.008-1.123)。在污染物方面,PM2.5,尤其是与交通相关的 PM2.5 部分,在各种模型调整下始终被认为是哮喘发病(HR = 1.064,95% CI:1.034-1.094)和住院(HR = 1.031,95% CI:1.010-1.052)的重要风险因素。低社会经济地位在成人哮喘的发展过程中也起到了重要作用:我们的研究为了解影响成人哮喘发展的因素提供了重要依据。监测和减少空气污染(尤其是 PM2.5)暴露、提倡更健康的生活方式以及解决社会经济不平等问题对于预防和管理哮喘非常重要。
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引用次数: 0
Lower Healthcare Access and Its Association With Individual Factors and Health-Related Quality of Life in Adults With Rare Diseases in Switzerland. 瑞士成人罕见病患者较低的医疗保健可及性及其与个人因素和与健康相关的生活质量的关系。
IF 2.6 3区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-09-25 eCollection Date: 2024-01-01 DOI: 10.3389/ijph.2024.1607548
Susanne Wehrli, Andrew A Dwyer, Matthias R Baumgartner, Carmen Lehmann, Markus A Landolt

Objectives: This study aims to determine clusters of access to healthcare among adults with rare diseases in Switzerland, identify associated individual characteristics of access, and impact on health-related quality of life (HRQoL).

Methods: Swiss adults (N = 341) diagnosed with a rare disease completed an online survey including the Perception of Access to Healthcare Questionnaire (PAHQ) and Short Form Health Survey (SF-12). We employed partition around medoids algorithm to identify patient clusters based on the PAHQ. Various sociodemographic/disease-related factors and HRQoL were assessed.

Results: We identified two patient clusters: higher (n = 227) and lower access (n = 114). Significantly associated with lower access were an unstable disease course (p < 0.05), increased number of misdiagnoses (p < 0.05), and diseases affecting the nervous system (p < 0.01). Membership in the lower access cluster was significantly associated with worse HRQoL (p < 0.05).

Conclusion: Findings highlight the need for comprehensive assessment of healthcare access in adults with rare diseases and identifies potential targets for tailored interventions.

目的:本研究旨在确定瑞士患有罕见病的成年人中获得医疗服务的群体:本研究旨在确定瑞士患有罕见病的成年人获得医疗保健服务的情况,识别获得医疗保健服务的相关个人特征,以及对健康相关生活质量(HRQoL)的影响:方法:被诊断患有罕见病的瑞士成年人(N = 341)完成了一项在线调查,其中包括 "对医疗服务可及性的感知问卷"(PAHQ)和 "简表健康调查"(SF-12)。我们采用 medoids 周围分区算法,根据 PAHQ 确定患者群组。对各种社会人口学/疾病相关因素和 HRQoL 进行了评估:结果:我们确定了两个患者集群:就诊率较高的(n = 227)和就诊率较低的(n = 114)。病程不稳定(p < 0.05)、误诊次数增加(p < 0.05)和影响神经系统的疾病(p < 0.01)与就诊率较低有显著相关性。结论:研究结果表明,有必要对患者的健康状况进行全面评估:研究结果突出表明,有必要对患有罕见病的成年人获得医疗保健的情况进行全面评估,并确定有针对性干预措施的潜在目标。
{"title":"Lower Healthcare Access and Its Association With Individual Factors and Health-Related Quality of Life in Adults With Rare Diseases in Switzerland.","authors":"Susanne Wehrli, Andrew A Dwyer, Matthias R Baumgartner, Carmen Lehmann, Markus A Landolt","doi":"10.3389/ijph.2024.1607548","DOIUrl":"10.3389/ijph.2024.1607548","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to determine clusters of access to healthcare among adults with rare diseases in Switzerland, identify associated individual characteristics of access, and impact on health-related quality of life (HRQoL).</p><p><strong>Methods: </strong>Swiss adults (<i>N</i> = 341) diagnosed with a rare disease completed an online survey including the Perception of Access to Healthcare Questionnaire (PAHQ) and Short Form Health Survey (SF-12). We employed partition around medoids algorithm to identify patient clusters based on the PAHQ. Various sociodemographic/disease-related factors and HRQoL were assessed.</p><p><strong>Results: </strong>We identified two patient clusters: higher (<i>n</i> = 227) and lower access (<i>n</i> = 114). Significantly associated with lower access were an unstable disease course (<i>p</i> < 0.05), increased number of misdiagnoses (<i>p</i> < 0.05), and diseases affecting the nervous system (<i>p</i> < 0.01). Membership in the lower access cluster was significantly associated with worse HRQoL (<i>p</i> < 0.05).</p><p><strong>Conclusion: </strong>Findings highlight the need for comprehensive assessment of healthcare access in adults with rare diseases and identifies potential targets for tailored interventions.</p>","PeriodicalId":14322,"journal":{"name":"International Journal of Public Health","volume":"69 ","pages":"1607548"},"PeriodicalIF":2.6,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11461209/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142390509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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