Objectives: This study aimed to examine trends in relative and absolute social inequality in overweight/obesity among Danish infants born between 2002 and 2022.
Methods: The study applied yearly cross-sectional data on infants' weight and length at age 6-10 months, n = 63,100. Data was linked with parental education from population registers. Social inequality was measured by OR, relative index of inequality (RII), and slope index of inequality (SII). Trend tests measured changes over time.
Results: No difference in odds for overweight/obesity by parental education was observed between 2002 and 2004, but from 2005 social inequality in overweight/obesity was revealed. The OR for overweight/obesity ranged from 1.20 (95% CI: 0.76-1.89) to 2.31 (95% CI: 1.64-3.25) for infants of parents with lowest educational attainment. RII ranged from 0.78 to 0.41 (test for trend, p = 0.179) and SII ranged from -0.92 to -4.54 (test for trend, p = 0.026) indicating a persistent relative social inequality and an increase in absolute social inequality in overweight/obesity from 2002 to 2022, respectively.
Conclusion: The study revealed persistent relative social inequality and increased absolute social inequality in overweight/obesity among Danish infants from 2002 to 2022.
{"title":"Trends in Social Inequality in Overweight and Obesity Among Danish Infants, 2002-2022.","authors":"Lis Marie Pommerencke, Sanne Ellegård Jørgensen, Sofie Weber Pant, Rikke Rothkegel Carlsson, Camilla Thørring Bonnesen, Lene Kierkegaard, Mette Rasmussen, Michael Davidsen, Trine Pagh Pedersen","doi":"10.3389/ijph.2025.1608203","DOIUrl":"10.3389/ijph.2025.1608203","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to examine trends in relative and absolute social inequality in overweight/obesity among Danish infants born between 2002 and 2022.</p><p><strong>Methods: </strong>The study applied yearly cross-sectional data on infants' weight and length at age 6-10 months, n = 63,100. Data was linked with parental education from population registers. Social inequality was measured by OR, relative index of inequality (RII), and slope index of inequality (SII). Trend tests measured changes over time.</p><p><strong>Results: </strong>No difference in odds for overweight/obesity by parental education was observed between 2002 and 2004, but from 2005 social inequality in overweight/obesity was revealed. The OR for overweight/obesity ranged from 1.20 (95% CI: 0.76-1.89) to 2.31 (95% CI: 1.64-3.25) for infants of parents with lowest educational attainment. RII ranged from 0.78 to 0.41 (test for trend, p = 0.179) and SII ranged from -0.92 to -4.54 (test for trend, p = 0.026) indicating a persistent relative social inequality and an increase in absolute social inequality in overweight/obesity from 2002 to 2022, respectively.</p><p><strong>Conclusion: </strong>The study revealed persistent relative social inequality and increased absolute social inequality in overweight/obesity among Danish infants from 2002 to 2022.</p>","PeriodicalId":14322,"journal":{"name":"International Journal of Public Health","volume":"70 ","pages":"1608203"},"PeriodicalIF":2.4,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12399434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144992258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-14eCollection Date: 2025-01-01DOI: 10.3389/ijph.2025.1608716
Olabanjo Ogunsola, Laura M Gaydos, Oluseye Ajayi, Maria Dieci, Nadi Kaonga, Olutosin Awolude, Priscilla Ezemelue, Tyree Staple, Kabiru Salami, Ifeoma Idigbe, Oliver Ezechi, Lisa Flowers
Objectives: In this protocol, we describe a planned intervention to adapt the Mother Mentor (MoMent) peer support program for women living with HIV (WLWH). WLWH face a six-fold higher risk of cervical cancer, yet screening and treatment rates remain low in Nigeria.
Methods: Using an implementation science approach, we will engage key stakeholders-including ministries of health, NACA, professional bodies, WLWH, Mentor Mothers, healthcare providers, and development partners (e.g., WHO, US CDC, USAID)-through deliberative democracy to adapt and expand MoMent for home-based HPV screening and follow-up treatment. We will pilot the adapted MoMent HIV+HCC program with 1,500 women in 15 health facilities across Nigeria's five geopolitical zones. The RE-AIM framework will guide evaluation of reach, adoption, fidelity, effectiveness, and sustainability.
Results: This study is designed to contribute to WHO's global strategy to eliminate cervical cancer by improving access to home-based screening and care in low-resource settings.
Conclusion: Findings will inform national HPV prevention efforts and may drive broader integration into Nigeria's cervical cancer program.
{"title":"The CHESS Protocol: A Mixed-Methods Evaluation of an HPV Screening Intervention for Women Living With HIV in Nigeria.","authors":"Olabanjo Ogunsola, Laura M Gaydos, Oluseye Ajayi, Maria Dieci, Nadi Kaonga, Olutosin Awolude, Priscilla Ezemelue, Tyree Staple, Kabiru Salami, Ifeoma Idigbe, Oliver Ezechi, Lisa Flowers","doi":"10.3389/ijph.2025.1608716","DOIUrl":"10.3389/ijph.2025.1608716","url":null,"abstract":"<p><strong>Objectives: </strong>In this protocol, we describe a planned intervention to adapt the Mother Mentor (MoMent) peer support program for women living with HIV (WLWH). WLWH face a six-fold higher risk of cervical cancer, yet screening and treatment rates remain low in Nigeria.</p><p><strong>Methods: </strong>Using an implementation science approach, we will engage key stakeholders-including ministries of health, NACA, professional bodies, WLWH, Mentor Mothers, healthcare providers, and development partners (e.g., WHO, US CDC, USAID)-through deliberative democracy to adapt and expand MoMent for home-based HPV screening and follow-up treatment. We will pilot the adapted MoMent HIV+HCC program with 1,500 women in 15 health facilities across Nigeria's five geopolitical zones. The RE-AIM framework will guide evaluation of reach, adoption, fidelity, effectiveness, and sustainability.</p><p><strong>Results: </strong>This study is designed to contribute to WHO's global strategy to eliminate cervical cancer by improving access to home-based screening and care in low-resource settings.</p><p><strong>Conclusion: </strong>Findings will inform national HPV prevention efforts and may drive broader integration into Nigeria's cervical cancer program.</p><p><strong>Clinical trial registration: </strong>Clinicaltrials.gov, identifier NCT06751030.</p>","PeriodicalId":14322,"journal":{"name":"International Journal of Public Health","volume":"70 ","pages":"1608716"},"PeriodicalIF":2.4,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12391886/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144954065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-06eCollection Date: 2025-01-01DOI: 10.3389/ijph.2025.1608291
Julia Bartkova, Rei Ogawa
{"title":"Child Safety First: A Public Health Initiative to Address Pediatric Non-Accidental Burns in Central Europe.","authors":"Julia Bartkova, Rei Ogawa","doi":"10.3389/ijph.2025.1608291","DOIUrl":"https://doi.org/10.3389/ijph.2025.1608291","url":null,"abstract":"","PeriodicalId":14322,"journal":{"name":"International Journal of Public Health","volume":"70 ","pages":"1608291"},"PeriodicalIF":2.4,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12365518/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144954006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-28eCollection Date: 2025-01-01DOI: 10.3389/ijph.2025.1608095
Batoul Issam Abbas, Hasan Houssein Abbass, Azza Ali Ali Hasan, Abdul Hamid Mohamad Alwan, Nourhan Hussein Azzam, Joudy Hussien Al Sahmarani, Ilham Sleiman Hassan, Noama Wassek El Husseini, Bahaa Wadih Bou Dargham
Objectives: This study aims to assess the knowledge and attitude of medical students in Lebanon towards disaster medicine.
Methods: An exploratory online cross-sectional survey was conducted on 388 medical students from different educational levels and universities in Lebanon. The data was analyzed using the Statistical Package for Social Sciences (SPSS), considering a p-value of <0.05 as significant.
Results: The participants had a mean knowledge score of 12.19 ± 4.04 out of 25 questions. Those who received a disaster medicine educational course (19.1%) had a higher knowledge score (p-value <0.001). There was a significant association between the knowledge score on one hand, and the confidence level of respondents (p-value of 0.003) and their willingness to enroll in a disaster medicine course on the other hand (p-values <0.001).
Conclusion: It is evident that medical students in Lebanon possess a fair level of knowledge and a high attitude towards disaster medicine.
{"title":"Knowledge and Attitude of Medical Students in Lebanon Towards Disaster Medicine.","authors":"Batoul Issam Abbas, Hasan Houssein Abbass, Azza Ali Ali Hasan, Abdul Hamid Mohamad Alwan, Nourhan Hussein Azzam, Joudy Hussien Al Sahmarani, Ilham Sleiman Hassan, Noama Wassek El Husseini, Bahaa Wadih Bou Dargham","doi":"10.3389/ijph.2025.1608095","DOIUrl":"10.3389/ijph.2025.1608095","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to assess the knowledge and attitude of medical students in Lebanon towards disaster medicine.</p><p><strong>Methods: </strong>An exploratory online cross-sectional survey was conducted on 388 medical students from different educational levels and universities in Lebanon. The data was analyzed using the Statistical Package for Social Sciences (SPSS), considering a p-value of <0.05 as significant.</p><p><strong>Results: </strong>The participants had a mean knowledge score of 12.19 ± 4.04 out of 25 questions. Those who received a disaster medicine educational course (19.1%) had a higher knowledge score (p-value <0.001). There was a significant association between the knowledge score on one hand, and the confidence level of respondents (p-value of 0.003) and their willingness to enroll in a disaster medicine course on the other hand (p-values <0.001).</p><p><strong>Conclusion: </strong>It is evident that medical students in Lebanon possess a fair level of knowledge and a high attitude towards disaster medicine.</p>","PeriodicalId":14322,"journal":{"name":"International Journal of Public Health","volume":"70 ","pages":"1608095"},"PeriodicalIF":2.4,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12336067/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144821432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-25eCollection Date: 2025-01-01DOI: 10.3389/ijph.2025.1608347
Melanie Ehrler, Alexandra Vogt, Dominique Eichelberger, Matthias Greutmann, Cornelia F Hagmann, Oskar G Jenni, Oliver Kretschmar, Markus A Landolt, Beatrice Latal, Flavia M Wehrle
Objectives: The COVID-19 pandemic significantly affected global psychological well-being. We explored long-term trajectories of adults' well-being from before the pandemic through its progression and identified risk factors for compromised well-being.
Methods: Psychological well-being of a diverse group of 481 adults (18-74 years) was assessed prior to (T0) and during the pandemic (T1-T5: 04-05/2020, 10-11/2020, 04-05/2021, 10-11/2021, 04-05/2022). Latent variable mixture modelling identified subgroups with distinct trajectories of well-being. Ordinal regression analysis investigated risk factors for low well-being during the pandemic.
Results: Three subgroups with different trajectories were identified: 73% reported consistently good well-being; 21% experienced decreasing well-being; and 5% exhibited consistently low well-being. Decreasing or consistently low well-being was significantly associated with younger age, limited social support, caregiving responsibilities, concerns about COVID-19 infection, and stress due to pandemic-related changes.
Conclusion: While many individuals remained resilient, a vulnerable subgroup experienced mental health challenges over 2 years of the pandemic. Given the global scale, even a small affected proportion represents millions of people. Public health measures are essential to identify and support those at highest risk for impaired psychological well-being.
{"title":"Psychological Well-Being in Adults Across the COVID-19 Pandemic: A Two-Year Longitudinal Study.","authors":"Melanie Ehrler, Alexandra Vogt, Dominique Eichelberger, Matthias Greutmann, Cornelia F Hagmann, Oskar G Jenni, Oliver Kretschmar, Markus A Landolt, Beatrice Latal, Flavia M Wehrle","doi":"10.3389/ijph.2025.1608347","DOIUrl":"10.3389/ijph.2025.1608347","url":null,"abstract":"<p><strong>Objectives: </strong>The COVID-19 pandemic significantly affected global psychological well-being. We explored long-term trajectories of adults' well-being from before the pandemic through its progression and identified risk factors for compromised well-being.</p><p><strong>Methods: </strong>Psychological well-being of a diverse group of 481 adults (18-74 years) was assessed prior to (T0) and during the pandemic (T1-T5: 04-05/2020, 10-11/2020, 04-05/2021, 10-11/2021, 04-05/2022). Latent variable mixture modelling identified subgroups with distinct trajectories of well-being. Ordinal regression analysis investigated risk factors for low well-being during the pandemic.</p><p><strong>Results: </strong>Three subgroups with different trajectories were identified: 73% reported consistently good well-being; 21% experienced decreasing well-being; and 5% exhibited consistently low well-being. Decreasing or consistently low well-being was significantly associated with younger age, limited social support, caregiving responsibilities, concerns about COVID-19 infection, and stress due to pandemic-related changes.</p><p><strong>Conclusion: </strong>While many individuals remained resilient, a vulnerable subgroup experienced mental health challenges over 2 years of the pandemic. Given the global scale, even a small affected proportion represents millions of people. Public health measures are essential to identify and support those at highest risk for impaired psychological well-being.</p>","PeriodicalId":14322,"journal":{"name":"International Journal of Public Health","volume":"70 ","pages":"1608347"},"PeriodicalIF":2.4,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12331532/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144816578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-25eCollection Date: 2025-01-01DOI: 10.3389/ijph.2025.1608830
Halder J Abozait, Haseeba Khalid
{"title":"Considerations for Advancing Parkinson's Disease Research in Middle East, North Africa, and South Asia.","authors":"Halder J Abozait, Haseeba Khalid","doi":"10.3389/ijph.2025.1608830","DOIUrl":"10.3389/ijph.2025.1608830","url":null,"abstract":"","PeriodicalId":14322,"journal":{"name":"International Journal of Public Health","volume":"70 ","pages":"1608830"},"PeriodicalIF":2.4,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12331531/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144816577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: The pandemic was the most significant event affecting health systems in the last 100 years. Research shows that gender, age and socioeconomic status were associated with higher mortality during the pandemic. However, most studies are cross-sectional and country specific. This paper assesses sociodemographic characteristics associated with time and cause of death in Europe between 2018 and 2022.
Methods: The analysis includes 7,137 decedents aged over 50, using post-death interviews with proxy respondents, from the Survey on Health, Ageing, and Retirement in Europe (SHARE). Data from 28 countries, from SHARE waves 7 to 9, are examined using t-tests, chisquaretests and multivariate logit regression models, controlling for sociodemographic characteristics. The three binary outcome variable sindicate the time and cause of death.
Results: Being male, older, without a partner, self-reporting financial difficulties, and living in Eastern Europe were associated with an increased likelihood of dying during the pandemic. The association was stronger for deaths due to COVID-19, respiratory and infectious diseases.
Conclusion: The pandemic highlighted socioeconomic gradients in mortality. These results call for policymakers to prepare for future shocks, ensuring equal access to adequate care.
{"title":"Socioeconomic and Demographic Factors Associated With Mortality Before and During the COVID-19 Pandemic: An Analysis of 28 European Countries.","authors":"Paola Sillitti, Clément Meier, Olivier Mucchiut, Jürgen Maurer, Ralf J Jox","doi":"10.3389/ijph.2025.1608560","DOIUrl":"10.3389/ijph.2025.1608560","url":null,"abstract":"<p><strong>Objectives: </strong>The pandemic was the most significant event affecting health systems in the last 100 years. Research shows that gender, age and socioeconomic status were associated with higher mortality during the pandemic. However, most studies are cross-sectional and country specific. This paper assesses sociodemographic characteristics associated with time and cause of death in Europe between 2018 and 2022.</p><p><strong>Methods: </strong>The analysis includes 7,137 decedents aged over 50, using post-death interviews with proxy respondents, from the Survey on Health, Ageing, and Retirement in Europe (SHARE). Data from 28 countries, from SHARE waves 7 to 9, are examined using t-tests, chisquaretests and multivariate logit regression models, controlling for sociodemographic characteristics. The three binary outcome variable sindicate the time and cause of death.</p><p><strong>Results: </strong>Being male, older, without a partner, self-reporting financial difficulties, and living in Eastern Europe were associated with an increased likelihood of dying during the pandemic. The association was stronger for deaths due to COVID-19, respiratory and infectious diseases.</p><p><strong>Conclusion: </strong>The pandemic highlighted socioeconomic gradients in mortality. These results call for policymakers to prepare for future shocks, ensuring equal access to adequate care.</p>","PeriodicalId":14322,"journal":{"name":"International Journal of Public Health","volume":"70 ","pages":"1608560"},"PeriodicalIF":2.4,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12326546/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144794380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-17eCollection Date: 2025-01-01DOI: 10.3389/ijph.2025.1608128
Grace I Nwankwo, Ogonna N O Nwankwo, Onyinye U Anyanwu, Chinonyelum T Ezeonu, Chigozie I Uzomba, Michael A Akpoke, Anthony N Ikefuna
Objective: Peer physical violence (PPV) has been shown to be an early marker for development of other health-risk behaviours. This study assessed the prevalence and risk factors of PPV among in-school adolescents in a state in South-east, Nigeria.
Methods: This was a cross sectional study conducted among 1,296 in-school adolescents using the Global School-based students Health Survey questionnaire. Data on socio-demographic characteristics and factors associated with PPV were obtained and p-value <0.05 was considered significant.
Result: The overall mean age (S.D) of participants was 15.0 ± 2.0 years and the prevalence of PPV was 43.1%. In multivariate logistic regression, predictors of PPV were gambling (AOR: 1.56; 95%CI:1.13-2.16; p = 0.007), cigarette smoking (AOR: 1.85; 95%CI:1.01-3.40; p = 0.047), serious injury in the past 1 year (AOR: 2.29; 95%CI:1.78-2.95; p < 0.001) and bully victims (AOR: 1.70; 95% CI:1.28-2.25; p < 0.001). Older adolescent age (AOR:0.37; 95%CI:0.25-0.53; p < 0.001] and being religious (AOR: 0.70; 95%CI: 0.53-0.92; p = 0.011) were protective.
Conclusion: There is high prevalence of PPV in the study population. The risk factors were young adolescence age, bullying, gambling, cigarette smoking, having had a serious injury and not being religious. Stricter regulations on gambling through legislation, especially as it concerns age, and adoption of school policies against bullying and cigarette smoking are recommended.
{"title":"Prevalence and Predictors of Peer Physical Violence Among Adolescents in a Sub-National Region of Nigeria.","authors":"Grace I Nwankwo, Ogonna N O Nwankwo, Onyinye U Anyanwu, Chinonyelum T Ezeonu, Chigozie I Uzomba, Michael A Akpoke, Anthony N Ikefuna","doi":"10.3389/ijph.2025.1608128","DOIUrl":"10.3389/ijph.2025.1608128","url":null,"abstract":"<p><strong>Objective: </strong>Peer physical violence (PPV) has been shown to be an early marker for development of other health-risk behaviours. This study assessed the prevalence and risk factors of PPV among in-school adolescents in a state in South-east, Nigeria.</p><p><strong>Methods: </strong>This was a cross sectional study conducted among 1,296 in-school adolescents using the Global School-based students Health Survey questionnaire. Data on socio-demographic characteristics and factors associated with PPV were obtained and p-value <0.05 was considered significant.</p><p><strong>Result: </strong>The overall mean age (S.D) of participants was 15.0 ± 2.0 years and the prevalence of PPV was 43.1%. In multivariate logistic regression, predictors of PPV were gambling (AOR: 1.56; 95%CI:1.13-2.16; p = 0.007), cigarette smoking (AOR: 1.85; 95%CI:1.01-3.40; p = 0.047), serious injury in the past 1 year (AOR: 2.29; 95%CI:1.78-2.95; p < 0.001) and bully victims (AOR: 1.70; 95% CI:1.28-2.25; p < 0.001). Older adolescent age (AOR:0.37; 95%CI:0.25-0.53; p < 0.001] and being religious (AOR: 0.70; 95%CI: 0.53-0.92; p = 0.011) were protective.</p><p><strong>Conclusion: </strong>There is high prevalence of PPV in the study population. The risk factors were young adolescence age, bullying, gambling, cigarette smoking, having had a serious injury and not being religious. Stricter regulations on gambling through legislation, especially as it concerns age, and adoption of school policies against bullying and cigarette smoking are recommended.</p>","PeriodicalId":14322,"journal":{"name":"International Journal of Public Health","volume":"70 ","pages":"1608128"},"PeriodicalIF":2.4,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12310562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144759980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-15eCollection Date: 2025-01-01DOI: 10.3389/ijph.2025.1608343
Sarah R Haile, David Kronthaler
Objectives: The COVID-19 pandemic has led to many studies of seroprevalence. A number of methods exist in the statistical literature to correctly estimate disease prevalence or seroprevalence in the presence of diagnostic test misclassification, but these methods seem to be not routinely used in the public health literature. We aimed to examine how widespread the problem is in recent publications, and to quantify the magnitude of bias introduced when correct methods are not used.
Methods: A systematic review was performed to estimate how often public health researchers accounted for diagnostic test performance in estimates of seroprevalence.
Results: Of the seroprevalence studies sampled, 77% (95% CI 72%-82%) failed to account for sensitivity and specificity. In high impact journals, 72% did not correct for test characteristics, and 34% did not report sensitivity or specificity. The most common type of correction was the Rogen-Gladen formula (57%, 45%-69%), followed by Bayesian approaches (32%, 21%-44%). Rates of correction increased slightly over time, but type of correction did not change.
Conclusion: Researchers conducting studies of prevalence should report sensitivity and specificity of the diagnostic test and correctly account for these characteristics.
目的:COVID-19大流行导致了许多关于血清患病率的研究。统计文献中存在许多方法,可以在诊断测试错误分类的情况下正确估计疾病患病率或血清患病率,但这些方法似乎并未在公共卫生文献中常规使用。我们的目的是研究这个问题在最近的出版物中有多普遍,并量化当没有使用正确的方法时引入的偏倚的程度。方法:进行系统回顾,以估计公共卫生研究人员在估计血清阳性率时考虑诊断测试表现的频率。结果:在抽样的血清阳性率研究中,77% (95% CI 72%-82%)未能解释敏感性和特异性。在高影响力期刊中,72%的人没有纠正测试特征,34%的人没有报告敏感性或特异性。最常见的矫正类型是Rogen-Gladen公式(57%,45%-69%),其次是贝叶斯方法(32%,21%-44%)。随着时间的推移,纠正率略有增加,但纠正的类型没有改变。结论:进行患病率研究的研究人员应报告诊断测试的敏感性和特异性,并正确考虑这些特征。
{"title":"Potential for Bias in Prevalence Estimates when Not Accounting for Test Sensitivity and Specificity: A Systematic Review of COVID-19 Seroprevalence Studies.","authors":"Sarah R Haile, David Kronthaler","doi":"10.3389/ijph.2025.1608343","DOIUrl":"10.3389/ijph.2025.1608343","url":null,"abstract":"<p><strong>Objectives: </strong>The COVID-19 pandemic has led to many studies of seroprevalence. A number of methods exist in the statistical literature to correctly estimate disease prevalence or seroprevalence in the presence of diagnostic test misclassification, but these methods seem to be not routinely used in the public health literature. We aimed to examine how widespread the problem is in recent publications, and to quantify the magnitude of bias introduced when correct methods are not used.</p><p><strong>Methods: </strong>A systematic review was performed to estimate how often public health researchers accounted for diagnostic test performance in estimates of seroprevalence.</p><p><strong>Results: </strong>Of the seroprevalence studies sampled, 77% (95% CI 72%-82%) failed to account for sensitivity and specificity. In high impact journals, 72% did not correct for test characteristics, and 34% did not report sensitivity or specificity. The most common type of correction was the Rogen-Gladen formula (57%, 45%-69%), followed by Bayesian approaches (32%, 21%-44%). Rates of correction increased slightly over time, but type of correction did not change.</p><p><strong>Conclusion: </strong>Researchers conducting studies of prevalence should report sensitivity and specificity of the diagnostic test and correctly account for these characteristics.</p>","PeriodicalId":14322,"journal":{"name":"International Journal of Public Health","volume":"70 ","pages":"1608343"},"PeriodicalIF":2.4,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12303856/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144742118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-15eCollection Date: 2025-01-01DOI: 10.3389/ijph.2025.1608791
Roberto Daniel Sirvent, Bilal Irfan
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