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EVALUATION OF SERUM LACTATE AS A PREDICTOR OF MORBIDITY AND MORTALITY IN SEPSIS AND TRAUMA PATIENTS 将血清乳酸作为败血症和创伤患者发病率和死亡率的预测指标进行评估
Pub Date : 2024-05-01 DOI: 10.36106/ijsr/4205470
Vivek M. Kele, Lisha Suraj
Lactate is produced in the cells in anaerobic metabolism of glucose for the generation of adenosine triphosphate (ATP) and may be an indicator ofoccult or global hypoperfusion. Thus, early serum lactate measurement may be a prognostic indicator of the outcome in critically ill patients.Therefore, the present study was conducted to assess the value of serial measurements of serum lactate levels in the predicting the outcome. Afterobtaining approval from the Institutional Ethics Committee and written voluntary informed consent from the relatives/patients, a total of 50 casesof trauma to chest or abdomen and patients with sepsis as per quick Sequential Organ Failure Assessment (qSOFA) score or having SystemicInammatory Response Syndrome (SIRS) were included. Serum lactate levels were measured at 24 and 48 hours and the nal outcome andduration of discharge was noted. It was observed that serum lactate levels were similar in terms of gender, presence of multiple organ dysfunctionsyndrome (MODS) and type of treatment. Baseline lactate levels were similar. Death was associated with signicant increase in serum lactatelevels at 24 and 48 hours while a decrease in levels were associated with early discharge (at less than 7 days). It can be effectively concluded thatserial measurements of serum lactate levels are of prognostic value to predict the outcome in critically ill patient with increasing levels being aharbinger of potentially fatal outcomes.
乳酸是细胞中葡萄糖无氧代谢生成三磷酸腺苷(ATP)时产生的,可作为先兆或全身灌注不足的指标。因此,本研究旨在评估连续测量血清乳酸水平在预测重症患者预后方面的价值。在获得机构伦理委员会的批准和亲属/患者的书面自愿知情同意后,共纳入了50例胸部或腹部外伤患者,以及根据快速器官功能衰竭顺序评估(qSOFA)评分患有脓毒症或患有系统性炎症反应综合征(SIRS)的患者。在 24 小时和 48 小时测量血清乳酸水平,并记录 nal 结果和出院时间。观察发现,血清乳酸水平在性别、是否存在多器官功能障碍综合征(MODS)和治疗类型方面相似。基线乳酸水平相似。死亡与 24 小时和 48 小时血清乳酸水平的显著上升有关,而血清乳酸水平的下降与提前出院(少于 7 天)有关。由此可以得出结论,血清乳酸水平的临床测量对于预测危重病人的预后具有重要价值,乳酸水平的升高预示着潜在的致命结局。
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引用次数: 0
DIAGNOSTIC DILEMMA: DISCREPANT PATHOLOGY REPORTS IN A CASE OF THIGH MASS 诊断难题:一个大腿肿块病例中不一致的病理报告
Pub Date : 2024-05-01 DOI: 10.36106/ijsr/0900147
Srijan Shailesh Pandey, Ananta Kulkarni, Mayur Babaurao Tayde, Namrata Ravi Amolik, Suhas G Gaykhe
Spindle cell sarcoma is a soft-tissue tumour which can start in the bone. Spindle cell sarcoma is referred to in this way due to the appearance of itstumour cells when they are looked at under a microscope. The cells which make up a spindle cell sarcoma are long and narrow, which is known as a'spindle-cell shape'(1,7).Spindle cell carcinoma can affect any age group but mostly affects age group of over 40.It more commonly affects menthan women.[2,5]Myositis ossicans is a reaction to a bruise in a muscle that has been injured. During the healing of the bruise, calcium can becomedeposited in the bruise causing a hard bone like structure within the muscle.The knowledge of case where both spindle cell carcinoma and myositisossicans is present is very important for the clinical physician to diagnose and treat properly.[3,8]
纺锤形细胞肉瘤是一种软组织肿瘤,可始于骨骼。纺锤形细胞肉瘤之所以被称为纺锤形细胞肉瘤,是因为在显微镜下观察其肿瘤细胞的外观。构成纺锤细胞肉瘤的细胞又长又窄,被称为 "纺锤细胞形状"(1,7)。纺锤细胞癌可影响任何年龄组,但主要影响 40 岁以上的年龄组。[2,5]肌肉炎(Myositis ossicans)是肌肉受伤后出现的一种瘀伤反应。在瘀伤愈合过程中,钙会沉积在瘀伤处,导致肌肉内出现类似硬骨的结构。[3,8] 了解纺锤形细胞癌和肌炎同时存在的病例对于临床医生正确诊断和治疗非常重要。
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引用次数: 0
AN OBSERVATIONAL STUDY ANALYZING THE TREND OF CARDIOLOGIST DRIVEN FETAL ECHOCARDIOGRAPHY IN INDIAN SCENARIO WITH A COMPARISON OF PRENATAL VERSUS POSTNATAL FINDINGS: LESSONS LEARNED DURING A LONGITUDINAL ASSESSMENT OF FETAL CARDIA. 一项观察性研究,通过比较产前与产后发现,分析印度胎儿超声心动图由心脏专科医生主导的趋势:胎儿贲门纵向评估的经验教训。
Pub Date : 2024-05-01 DOI: 10.36106/ijsr/4707583
Mandal Krishna D, Chaudhuri Maitri, Amatya Unnati, Kumar Gaurav, Tomar Munesh
Background and aims: Fetal echocardiography stands as the diagnostic pivot for serial assessment of cardiovascular anatomy and hemodynamicsof fetus from rst trimester to postnatal life. It offers high sensitivity in accurate detection of cardiac development and lesions during intrauterinelife. The gold standard remains as postnatal or autopsy validation of antenatal ndings. Our objective was data analysis of the factors determiningreferral pattern to pediatric cardiologist, conrmation of the diagnosis and appropriateness of parental counseling and pregnancy managementstrategies. an observational study retrospectively reviewed all pregnant women reporting for fetal e Methods and results: chocardiography totertiary pediatric cardiac center from February 2021 to July 2023. Relevant factors for referral to pediatric cardiology were tabulated. Fetalechocardiography protocol was adapted from American Institute of Ultrasound in Medicine guidelines with Extended Cardiac EchocardiographicExamination protocol. Fetal echocardiographic results were categorized into simple, severe and functional defects. The fetuses were reviewedpostnatally by neonatal echocardiography. Total of 330 pregnant ladies reported for fetal echocardiography in our department, 268 (81.2%) of themwere referred cases. The most common reasons for referral were intra-cardiac echogenic foci (ICEF) in 87 (32.5%) cases followed by suspectedcongenital heart disease (CHD) in 80 (29.9%), maternal illness in 39(14.6%), extra-cardiac anomaly 22 (8.2%), family history of CHD 18(6.7%),fetal arrhythmia 11(4.1%), isolated valve regurgitation seven (2.6%), assisted reproduction three (1.1%) and cardiac mass in one (0.3%) case. Wedetected cardiac abnormality in 113 (34.2%) fetuses. Of those, 55 (48.7%) had severe CHD, 32 (28.3%) had simple defect and 26(23%) hadfunctional heart defect. 70 (62%) were born with congenital heart disease; of which 15(21.4%) were operated at the appropriate postnatal age.Conclusions: fetal echocardiography by pediatric cardiologist delivers additive diagnostic value and facilitates appropriate parental counselingfrom mid gestation, helps in proper perinatal triaging and continued cardiac care from fetus- to newborn.
背景和目的:胎儿超声心动图是对胎儿从  初孕期到出生后的心血管解剖结构和血流动力学进行连续评估的诊断支点。它在准确检测胎儿宫内心脏发育和病变方面具有很高的灵敏度。金标准仍然是产后或尸检对产前 ndings 的验证。我们的目标是对决定向儿科心脏病专家转诊模式的因素、诊断结论rmation 以及家长咨询和妊娠管理策略的适当性进行数据分析。这项观察性研究回顾性地审查了2021年2月至2023年7月期间所有向三级儿科心脏病中心报告胎儿e方法和结果:心电图。表列出了转诊至儿科心脏病学的相关因素。胎儿超声心动图检查方案改编自美国超声医学研究所指南和扩展心脏超声心动图检查方案。胎儿超声心动图结果分为简单缺陷、严重缺陷和功能缺陷。胎儿在出生后接受新生儿超声心动图检查。我科共有 330 名孕妇接受了胎儿超声心动图检查,其中 268 例(81.2%)为转诊病例。最常见的转诊原因是心内回声灶(ICEF)87 例(32.5%),其次是疑似先天性心脏病(CHD)80 例(29.9%)、孕产妇疾病 39 例(14.6%)、心外畸形 22 例(8.2%)、先天性心脏病家族史 18 例(6.7%)、胎儿心律失常 11 例(4.1%)、孤立性瓣膜返流 7 例(2.6%)、辅助生殖 3 例(1.1%)和心脏肿块 1 例(0.3%)。在 113 个(34.2%)胎儿中,我们发现了心脏异常。其中 55 个(48.7%)胎儿患有严重的先天性心脏病,32 个(28.3%)胎儿患有单纯性心脏病,26 个(23%)胎儿患有功能性心脏病。结论:由儿科心脏病专家进行胎儿超声心动图检查具有附加诊断价值,有助于从妊娠中期开始为父母提供适当的咨询,帮助进行适当的围产期分诊以及从胎儿到新生儿的持续心脏护理。
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引用次数: 0
FACTORS ASSOCIATED WITH PROLAPSE OF UTERUS 与子宫脱垂有关的因素
Pub Date : 2024-05-01 DOI: 10.36106/ijsr/3904352
Ashwini S. Hambarde, Sandeep R. Hambarde
Background: Prolapse of uterus is a very common reproductive health problem in women in India. It is detrimental to emotional, physical andpsychosocial well being of a woman. Factors affecting prolapse of uterus, if studied well,will help for preventive measures. Aim and Objective:To study the factors associated with uterine prolapse at SIMS,Manglore. Material and Methods: Total 60 patients diagnosed with uterine prolapsewere studied. Data was collected with standard questions. Data included Detailed history,clinical examination and sociodemographic data. It wasanalysed with appropriate statistical tests. Results: Mean age of the patients in our study was 46 ± 3 years. Majority i.e. 41.66% of the patients werein the age group of 41-50 years .Patients from age group of 31-40 years were 10%. Majority patients were contribution with 3-4 parity. 66.66%patients were menopausal and 33.33% patients were premenopausal. 1st degree prolapse was not observed in any patients. 2nd degree and 3rddegree prolapsed was observed in 70% and 20% patients respectively.Procidentia was observed in 10% patients. Cystocele and rectocele wereobserved in 90% patients. “something coming out of vagina“ was the most common complaint of the patients (100%).11
背景:子宫脱垂是印度妇女非常常见的生殖健康问题。它对妇女的情感、身体和社会心理健康有害无益。如果对影响子宫脱垂的因素进行深入研究,将有助于采取预防措施。目的和目标:在芒格洛尔 SIMS 研究与子宫脱垂相关的因素。材料与方法:共对 60 名确诊为子宫脱垂的患者进行了研究。通过标准问题收集数据。数据包括详细病史、临床检查和社会人口学数据。通过适当的统计检验对数据进行分析。结果研究中患者的平均年龄为 46 ± 3 岁。大多数患者(41.66%)的年龄在 41-50 岁之间,31-40 岁的患者占 10%。大多数患者为 3-4 胎。66.66%的患者处于绝经期,33.33%的患者处于绝经前期。所有患者均未发现 1 度脱垂。10%的患者有子宫前突。90%的患者出现膀胱阴道脱垂和直肠阴道脱垂。"有东西从阴道里出来 "是患者最常见的主诉(100%)。
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引用次数: 0
A STUDY OF ASSOCIATION OF RHEUMATOID FACTOR POSITIVITY IN PATEINTS WITH CHRONIC TONSILLITIS 慢性扁桃体炎患者类风湿因子阳性相关性研究
Pub Date : 2024-05-01 DOI: 10.36106/ijsr/9303861
Santosh U. P., Baneet Chadha
Chronic Tonsillitis is one of the most common chronic inammatory conditions occurring as a result of bacterial and environmental factors withCD4+ cells predominance, which is also characteristically seen Rheumatoid Arthritis, although the exact pathogenesis remain unknown. Delayeddiagnosis and prompt treatment of Rheumatoid arthritis is a signicant factor leading to morbidity in elderly population. Aim:To nd associationbetween Rheumatoid Factor positivity in patients with Chronic Tonsillitis Materials and Methods:Atotal of 50 patients were selected who werediagnosed with Chronic Tonsillitis after fullment of inclusion and exclusion criteria, in whom Rheumatoid Factor serology was evaluated andstudied. Results:Astatistically signicant Rheumatoid Factor positivity were obtained - 13 out of 50 patients (26%) with a p<0.001. No statisticalsignicance was obtained when Rheumatoid Factor positivity and negativity was compared with age and gender distribution of the patients.Conclusion: Early evaluation of Rheumatoid Factor helps ensure better outcome on patient's quality of life by early adequate and effectivetreatment.
慢性扁桃体炎是最常见的慢性ammatory 病症之一,由细菌和环境因素引起,以CD4+细胞为主,这也是类风湿性关节炎的特征,但确切的发病机制仍不清楚。类风湿性关节炎的延迟诊断和及时治疗是导致老年人发病的一个重要cant因素。目的: 慢性扁桃体炎患者类风湿因子阳性与慢性扁桃体炎之间的关系 材料与方法:根据纳入和排除标准,共选取了50名被诊断为慢性扁桃体炎的患者,对其类风湿因子血清学进行了评估和研究。结果:50 例患者中有 13 例(26%)类风湿因子阳性,P<0.001。将类风湿因子阳性和阴性与患者的年龄和性别分布进行比较,没有统计学意义cance:结论:类风湿因子的早期评估有助于通过早期适当和有效的治疗,确保患者的生活质量得到更好的改善。
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引用次数: 0
EFFICACY OF SEMONT MANEUVER VS GUFONI MANEUVER IN IMPROVING THE QUALITY OF LIFE IN BPPV PATIENTS: A COMPARATIVE STUDY Semont 手法与 Gufoni 手法在改善 Bppv 患者生活质量方面的疗效:比较研究
Pub Date : 2024-05-01 DOI: 10.36106/ijsr/0801949
Preeti Sangwan (PT), Sonia Saroha(PT), Suman Rani (PT)
Objective: The aim of study was to nd out the effectiveness of the Epley maneuver, Semont maneuver and Gufoni maneuver on vertigo in BPPVand to evaluate the effectiveness of Epley maneuver and Semont maneuver and gufoni maneuver by using DHI, and ABC scale (Activities- SpecicBalance Condence scale). A comparative study, including google scholar, pubMed as data sources. 50 Methodology: patients were included bothmale and female were included with age group between 50-65 years. Duration of study was 4 weeks and method used for sampling was convenient.The treatment was done using Epley Maneuver and Semont Maneuver (Group A) and Epley and Gufoni Maneuver (Group B). Outcomes weremeasured using DHI and ABC scale, questionnaires at beginning and at the end of repositioning treatment. Mean result of the DHI of both Result:the groups shows that the post results of the group 2 have more effect than that of the group 1. The post of group 1 was 30.88 whereas the post of thegroup 2 was 6.96 And More the DHI the more functional disability is present. To become more functionally stable DHI should be lowered. Meansresult of the ABC of both the groups shows that the post results of the group 2 have more effect than that of the group. The post of the group 1 was73.06 and post of the group 2 was 81.00 and the more the ABC score the more Functional stability is present. The study concludes that Conclusion:there was marked improvement in functional balance, disability and postural control following Epley maneuver and Gufoni maneuver. Both thegroup have positive effects and was effective for long term intervention in vertigo patients and these maneuver can be added to the regularintervention for vestibular rehabilitation to decrease the symptoms of the patients.
研究目的研究的目的是,了解Epley手法、Semont手法和Gufoni手法对BPPV眩晕的有效性,并使用DHI和ABC量表(活动-特c平衡量表)评估Epley手法、Semont手法和Gufoni手法的有效性。比较研究,数据来源包括谷歌学术、PubMed。50 方法:患者包括男性和女性,年龄在 50-65 岁之间。研究时间为 4 周,取样方法为方便取样法。治疗采用 Epley 手法和 Semont 手法(A 组)以及 Epley 手法和 Gufoni 手法(B 组)。在复位治疗开始和结束时,使用 DHI 和 ABC 量表、调查问卷对结果进行测量。两组的 DHI 平均结果显示,第 2 组的术后效果比第 1 组更好。为了使功能更加稳定,应降低 DHI。两组 ABC 的均值结果表明,第 2 组的后期结果比第 1 组的影响更大。第 1 组的后期结果为 73.06,第 2 组的后期结果为 81.00,ABC 得分越高,功能越稳定。研究得出结论:采用 Epley 手法和 Gufoni 手法后,患者的功能平衡、残疾和姿势控制能力得到明显改善。这两组手法对眩晕患者的长期干预都有积极的作用和效果,可以将这些手法添加到常规的前庭康复干预中,以减轻患者的症状。
{"title":"EFFICACY OF SEMONT MANEUVER VS GUFONI MANEUVER IN IMPROVING THE QUALITY OF LIFE IN BPPV PATIENTS: A COMPARATIVE STUDY","authors":"Preeti Sangwan (PT), Sonia Saroha(PT), Suman Rani (PT)","doi":"10.36106/ijsr/0801949","DOIUrl":"https://doi.org/10.36106/ijsr/0801949","url":null,"abstract":"Objective: The aim of study was to nd out the effectiveness of the Epley maneuver, Semont maneuver and Gufoni maneuver on vertigo in BPPV\u0000and to evaluate the effectiveness of Epley maneuver and Semont maneuver and gufoni maneuver by using DHI, and ABC scale (Activities- Specic\u0000Balance Condence scale). A comparative study, including google scholar, pubMed as data sources. 50 Methodology: patients were included both\u0000male and female were included with age group between 50-65 years. Duration of study was 4 weeks and method used for sampling was convenient.\u0000The treatment was done using Epley Maneuver and Semont Maneuver (Group A) and Epley and Gufoni Maneuver (Group B). Outcomes were\u0000measured using DHI and ABC scale, questionnaires at beginning and at the end of repositioning treatment. Mean result of the DHI of both Result:\u0000the groups shows that the post results of the group 2 have more effect than that of the group 1. The post of group 1 was 30.88 whereas the post of the\u0000group 2 was 6.96 And More the DHI the more functional disability is present. To become more functionally stable DHI should be lowered. Means\u0000result of the ABC of both the groups shows that the post results of the group 2 have more effect than that of the group. The post of the group 1 was\u000073.06 and post of the group 2 was 81.00 and the more the ABC score the more Functional stability is present. The study concludes that Conclusion:\u0000there was marked improvement in functional balance, disability and postural control following Epley maneuver and Gufoni maneuver. Both the\u0000group have positive effects and was effective for long term intervention in vertigo patients and these maneuver can be added to the regular\u0000intervention for vestibular rehabilitation to decrease the symptoms of the patients.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"26 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141037348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PRIMARY MUSCULAR HYDATID CYST: A RARE OCCURRENCE. 原发性肌肉水瘤囊肿:罕见病例。
Pub Date : 2024-05-01 DOI: 10.36106/ijsr/8204667
P R Kshirsagar, U S Kanade, S Y Swami.
Hydatid disease is a parasitic infection caused by tapeworm echinococcus. The muscular localization of the hydatid cyst is extremely rare, usuallysecondary to hepatic or pulmonary disease and often clinically mistaken as soft tissue mass. Primary muscular hydatid cyst comprises less than 0.5% of the cases. Preoperative diagnosis is mandatory to avoid surgical contamination or future accidents.
包虫病是由棘球绦虫引起的寄生虫感染。包虫囊肿发生在肌肉部位的情况极为罕见,通常继发于肝脏或肺部疾病,临床上常被误诊为软组织肿块。原发性肌肉包虫囊肿占病例的 0.5% 以下。必须进行术前诊断,以避免手术污染或日后发生意外。
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引用次数: 0
POST-CHOLECYSTECTOMY RIGHT POSTERIOR SECTORAL BILE DUCT INJURY--A SINGLE INSTITUTION SERIES. 胆囊切除术后右侧后段胆管损伤--单个机构的系列研究。
Pub Date : 2024-05-01 DOI: 10.36106/ijsr/3505234
P. J. Halder, Swapnil Sharma
Injuries to sectoral bile ducts are less common than their major bile duct counterparts and present diagnostic and therapeutic challenges because oftheir rarity. Records of 17 patients (5 men and 12 women) with right posterior sectoral bile duct injuries managed in a single institution from year2000 to 2020 were analysed. Seven patients were managed non - operatively, and 9 patients underwent denitive surgery with a sectoral bile ductRoux – en – Y hepaticojejunostomy. Follow up ranged between 1 to 11 years. One patient had minor post-operative leak; 2 patients had anastomoticnarrowing managed by percutaneous balloon dilatation. Persistence of bile leak despite a “normal” biliary anatomy on Endoscopic RetrogradeCholangiography ± Magnetic Resonance Cholangio Pancreatography should lead to a suspicion of a right sectoral bile duct injury. Awareness ofthe condition, Magnetic Resonance Cholangio Pancreatography ± Percutaneous Transhepatic Cholangiography, and expert interpretation of thendings of imaging, are the keys to diagnosis of a Right Posterior Sectoral Bile Duct Injury.
扇形胆管损伤与大胆管损伤相比并不常见,由于其罕见性,给诊断和治疗带来了挑战。本文分析了 2000 年至 2020 年期间在一家医疗机构接受治疗的 17 例右后方扇形胆管损伤患者(5 男 12 女)的记录。其中 7 名患者接受了非手术治疗,9 名患者接受了扇形胆管鲁氏肝空肠吻合术(denitive surgery with a sectoral bile ductRoux - en - Y hepaticojejunostomy)。随访时间从 1 年到 11 年不等。一名患者术后出现轻微渗漏;两名患者通过经皮球囊扩张术处理了吻合口狭窄。尽管内镜逆行胰胆管造影术和磁共振胆胰造影术显示胆道解剖结构 "正常",但胆漏仍持续存在,这应导致怀疑右段胆管损伤。对病情的认识、磁共振胆胰造影术±经皮经肝胆管造影术以及专家对造影ndings 的解读是诊断右后段胆管损伤的关键。
{"title":"POST-CHOLECYSTECTOMY RIGHT POSTERIOR SECTORAL BILE DUCT INJURY--A SINGLE INSTITUTION SERIES.","authors":"P. J. Halder, Swapnil Sharma","doi":"10.36106/ijsr/3505234","DOIUrl":"https://doi.org/10.36106/ijsr/3505234","url":null,"abstract":"Injuries to sectoral bile ducts are less common than their major bile duct counterparts and present diagnostic and therapeutic challenges because of\u0000their rarity. Records of 17 patients (5 men and 12 women) with right posterior sectoral bile duct injuries managed in a single institution from year\u00002000 to 2020 were analysed. Seven patients were managed non - operatively, and 9 patients underwent denitive surgery with a sectoral bile duct\u0000Roux – en – Y hepaticojejunostomy. Follow up ranged between 1 to 11 years. One patient had minor post-operative leak; 2 patients had anastomotic\u0000narrowing managed by percutaneous balloon dilatation. Persistence of bile leak despite a “normal” biliary anatomy on Endoscopic Retrograde\u0000Cholangiography ± Magnetic Resonance Cholangio Pancreatography should lead to a suspicion of a right sectoral bile duct injury. Awareness of\u0000the condition, Magnetic Resonance Cholangio Pancreatography ± Percutaneous Transhepatic Cholangiography, and expert interpretation of the\u0000ndings of imaging, are the keys to diagnosis of a Right Posterior Sectoral Bile Duct Injury.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"130 S210","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141040679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HISTOMORPHOLOGICAL SPECTRUM OF APPENDICULAR LESIONS 阑尾病变的组织形态谱
Pub Date : 2024-05-01 DOI: 10.36106/ijsr/9802942
Mitali Priya Netam, Rachana S. Binayke
Introduction: The appendix, which is a vestigial organ in humans, is attached to caecum. The disease appendicitis is one of the commonest causesof acute abdomen. It is also the commonest reason of the emergency surgery that can lead to signicant morbidity and mortality. Usually when(1) appendectomy is done early, it relieves all the symptoms. The misdiagnosis related to the disease often leads to removal of uninamed appendix.The précised aetiology of appendicitis is uncertain, although the most common hypothesis is the obstruction of appendiceal lumen with secondaryinfection. The luminal and intraluminal pressure and due to the constant pressure, the thrombosis of appendicular vasculature and venousobstruction occurs resulting in ischemia. The bacteria enter the damaged mucosa and the pus forms inside the appendix eventually causing the(2) infarction and perforation. Aim: We aimed at determining the spectrum, histopathology and prevalence of lesions in appendix in our tertiary carehospital. Material And Methods: This is a retrospective study conducted in the department of pathology in tertiary care hospital, Mumbai over aperiod of 18 months. 300 specimens of appendicular lesions received during the study period. The specimens were xed in 10% formalin andstained with Haematoxylin and Eosin stain. The lesions were classied based on their histomorphological ndings. Results: This study includedtotal of 300 specimens of resected appendix. In the present study, the total sample number received during study period was 7840, Out of whichtotal number of appendicectomy specimens were 300 (3.82%). present study, the age group from the paediatric to geriatric age group wereconsidered. Majority of patients 99(33%) belong to 21-30 years age group. During the study period, a total number of 300 patients hadappendectomy out of which, the number of males was higher than females, with 60% of the cases being male, 40 % being female. In the presentstudy, the non-neoplastic lesions were found in majority. Out of 300 cases, he non- neoplastic lesions accounted for 295 cases (98.4%) andneoplastic lesions contributes 5 cases (1.66%). Conclusions: According to the current study, men are slightly more likely than women to developappendicitis with predominancy in second and third decades of life. In all cases of acute appendicitis, a histopathological examination of theappendix should be done since it provides crucial clinical information in addition to the operational results. The importance of histologicalinvestigation of every resected appendix is demonstrated by uncommon discoveries such as low grade appendiceal mucinous neoplasia andadenocarcinoma in clinically suspected acute appendicitis, the presence of which alters the subsequent therapy. Thus, we draw the conclusion thatthe histological analysis is still the best method for identifying appendiceal lesions.
简介阑尾是人类的附属器官,与盲肠相连。阑尾炎是急腹症最常见的病因之一。它也是最常见的急诊手术原因,可导致重大。通常情况下,如果(1) 阑尾切除术做得早,所有症状都会得到缓解。阑尾炎的病因尚不明确,但最常见的假设是阑尾管腔阻塞和继发感染。管腔和腔内压力以及由于持续的压力,阑尾血管血栓形成和静脉阻塞导致缺血。细菌进入受损的粘膜,在阑尾内形成脓液,最终导致(2) 梗死和穿孔。目的:我们旨在确定本三级医院阑尾病变的病谱、组织病理学和发病率。材料与方法:这是一项在孟买三级医院病理科进行的回顾性研究,历时 18 个月。研究期间共收到 300 份阑尾病变标本。标本在 10%福尔马林中 xed 并用血红素和伊红染色。根据病变的组织形态。结果:本研究共包括300份切除阑尾的标本。在本研究中,研究期间收到的样本总数为 7840 份,其中阑尾切除标本总数为 300 份(3.82%)。大多数患者 99 人(33%)属于 21-30 岁年龄组。在研究期间,共有 300 名患者进行了阑尾切除术,其中男性多于女性,男性占 60%,女性占 40%。在本研究中,非肿瘤性病变占大多数。在 300 例病例中,非肿瘤性病变占 295 例(98.4%),肿瘤性病变占 5 例(1.66%)。结论根据目前的研究,男性患阑尾炎的几率略高于女性,且主要发生在人生的第二和第三个十年。所有急性阑尾炎病例都应进行阑尾组织病理学检查,因为除了手术结果外,组织病理学检查还能提供重要的临床信息。在临床上疑似急性阑尾炎的病例中发现低级别阑尾粘液瘤和腺癌等不常见的病变,这些病变的存在会改变随后的治疗,这证明了对切除的阑尾进行组织学检查的重要性。因此,我们得出结论,组织学分析仍是鉴别阑尾病变的最佳方法。
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引用次数: 0
COMPARATIVE STUDY BETWEEN GRAHAM'S OMENTOPEXY AND MODIFIEDGRAHAM'S OMENTOPEXY IN TREATMENT OF PERFORATED DUODENAL ULCERS 格拉汉姆网膜切除术与改良格拉汉姆网膜切除术治疗十二指肠溃疡穿孔的比较研究
Pub Date : 2024-05-01 DOI: 10.36106/ijsr/8601354
Sudhanshu Sharma, Amal Mariyadas K. Boobily, Arbab Zaman
Background- Peptic ulcer perforation is an emergency and requires urgent surgical treatment. Due to in aberrant use of NSAID and high smokinghabits among the Indian population, frequency of peptic perforation is on the rise. Objective- This study is aimed at comparing success ratebetween Graham's omentopexy (GO) and modied - Graham's omentopexy (MGO) as an emergency management technique for duodenalperforation. Patients and methods- A prospective study was carried out for 1 year with 90 patients. GO was done in 50 patients and 40 patientsunderwent MGO between January 2023 and January 2024 in the Department of Surgery, Rajkiya Medical college Orai, Jalaun UP. Data regardingage, sex, time elapsed between onset of symptoms and hospital admission, comorbid diseases, morbidity, and mortality were recorded. ResultsMGO was associated with longer operative time. Mean hospital stay in GO group is higher than MGO group. Conclusion- Graham's patch repair isas effective as modied- Graham's patch repair in terms of morbidity and mortality. There is no statistically signicant difference in undergoingeither procedure for repair.
背景- 消化性溃疡穿孔是一种急症,需要紧急手术治疗。由于印度人滥用非甾体抗炎药和大量吸烟,消化性溃疡穿孔的发生率正在上升。目的--本研究旨在比较作为十二指肠穿孔急诊处理技术的格雷厄姆网膜剥脱术(GO)和改良格雷厄姆网膜剥脱术(MGO)的成功率。患者和方法--对90名患者进行了为期一年的前瞻性研究。2023年1月至2024年1月期间,50名患者接受了GO手术,40名患者接受了MGO手术。记录了患者的年龄、性别、从发病到入院的时间、合并症、发病率和死亡率。结果MGO的手术时间更长。GO组的平均住院时间高于MGO组。结论--就发病率和死亡率而言,Graham补片修补术与改良Graham补片修补术(ed Graham's patch repair)同样有效。从统计学角度看,两种修补术的差异并不。
{"title":"COMPARATIVE STUDY BETWEEN GRAHAM'S OMENTOPEXY AND MODIFIEDGRAHAM'S OMENTOPEXY IN TREATMENT OF PERFORATED DUODENAL ULCERS","authors":"Sudhanshu Sharma, Amal Mariyadas K. Boobily, Arbab Zaman","doi":"10.36106/ijsr/8601354","DOIUrl":"https://doi.org/10.36106/ijsr/8601354","url":null,"abstract":"Background- Peptic ulcer perforation is an emergency and requires urgent surgical treatment. Due to in aberrant use of NSAID and high smoking\u0000habits among the Indian population, frequency of peptic perforation is on the rise. Objective- This study is aimed at comparing success rate\u0000between Graham's omentopexy (GO) and modied - Graham's omentopexy (MGO) as an emergency management technique for duodenal\u0000perforation. Patients and methods- A prospective study was carried out for 1 year with 90 patients. GO was done in 50 patients and 40 patients\u0000underwent MGO between January 2023 and January 2024 in the Department of Surgery, Rajkiya Medical college Orai, Jalaun UP. Data regarding\u0000age, sex, time elapsed between onset of symptoms and hospital admission, comorbid diseases, morbidity, and mortality were recorded. ResultsMGO was associated with longer operative time. Mean hospital stay in GO group is higher than MGO group. Conclusion- Graham's patch repair is\u0000as effective as modied- Graham's patch repair in terms of morbidity and mortality. There is no statistically signicant difference in undergoing\u0000either procedure for repair.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"4 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141055811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
International journal of scientific research
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