Objective-To determine the accuracy of Multi Detector CT in characterizing colorectal lesions as benign or malignant - and its correlation with histopathology by studying bowel wall characteristics. - Methods 55 patients referred to the Department of Radiodiagnosis at a tertiary care centre in Trivandrum for contrast CT abdomen who had abnormal bowel wall thickening on CT. Lesions are classied on CT as benign or malignant based on bowel wall characteristics of wall thickening and staging is done in case of colorectal carcinoma. The ndings are then compared with the histopathological diagnosis. Results- Overall, CT had a sensitivity of 94.9%, specicity of 93.8%, Positive Predictive Value of 97.4% and a Negative Predictive Value of 88.2% in the diagnosis of malignant lesions. Accuracy of CT in diagnosing malignant lesions is 94.5%. Positive likelihood ratio is 15.2. and negative likelihood ratio is 0.05.CT is an excellent modality for tumour (T) staging in colorectal malignancy, as per our study, K=0.806 (excellent agreement).CT, though not highly accurate, can be used for lymph nodal (N) staging in colorectal malignancy, as per our study, K= 0.213 (fair agreement). Conclusion- Due to its high sensitivity and specicity, MDCT is an excellent modality in the diagnosis and differentiation of benign and malignant lesions of the colon and rectum,.It offers early detection of colorectal malignancy, provides staging of malignancies, helps in detection of metastasis, thereby aiding in the choice of treatment strategy. CT is an excellent modality for tumour (T) staging in colorectal malignancy, as per our study, K=0.806 (excellent agreement).
{"title":"ACCURACY OF COMPUTED TOMOGRAPHY IN CHARACTERISATION OF COLORECTAL LESIONS AS BENIGN OR MALIGNANT AND IN PRE-OP STAGING OF COLORECTAL CARCINOMA WITH HISTOPATHOLOGICAL CORRELATION","authors":"Deepika Nair, Rinku Mercy Thomas","doi":"10.36106/ijsr/6400251","DOIUrl":"https://doi.org/10.36106/ijsr/6400251","url":null,"abstract":"Objective-To determine the accuracy of Multi Detector CT in characterizing colorectal lesions as benign or malignant - and its correlation with\u0000histopathology by studying bowel wall characteristics. - Methods 55 patients referred to the Department of Radiodiagnosis at a tertiary care centre\u0000in Trivandrum for contrast CT abdomen who had abnormal bowel wall thickening on CT. Lesions are classied on CT as benign or malignant\u0000based on bowel wall characteristics of wall thickening and staging is done in case of colorectal carcinoma. The ndings are then compared with the\u0000histopathological diagnosis. Results- Overall, CT had a sensitivity of 94.9%, specicity of 93.8%, Positive Predictive Value of 97.4% and a\u0000Negative Predictive Value of 88.2% in the diagnosis of malignant lesions. Accuracy of CT in diagnosing malignant lesions is 94.5%. Positive\u0000likelihood ratio is 15.2. and negative likelihood ratio is 0.05.CT is an excellent modality for tumour (T) staging in colorectal malignancy, as per our\u0000study, K=0.806 (excellent agreement).CT, though not highly accurate, can be used for lymph nodal (N) staging in colorectal malignancy, as per our\u0000study, K= 0.213 (fair agreement). Conclusion- Due to its high sensitivity and specicity, MDCT is an excellent modality in the diagnosis and\u0000differentiation of benign and malignant lesions of the colon and rectum,.It offers early detection of colorectal malignancy, provides staging of\u0000malignancies, helps in detection of metastasis, thereby aiding in the choice of treatment strategy. CT is an excellent modality for tumour (T) staging\u0000in colorectal malignancy, as per our study, K=0.806 (excellent agreement).","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"86 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141037986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aishwarya Babasaheb Kotkar, Amit Benjamin, Sangeeta Muglikar, Sneha Jethwani, Dhruti Shah
Background: Enamel matrix derivative (EMD) has been widely used in periodontal regenerative treatment and the xenograft biomaterials show good biocompatibility and osteoconductivity of demineralized bovine bone matrix. So, to evaluate the improvement in clinical outcomes when Enamel Matrix Protein Derivative is used as an adjunct to Bovine-Derived Xenograft in intrabony defects of chronic periodontitis patients. Material And Methodology: In this systematic review, randomized controlled trials in subjects with periodontitis in the age group of 25-70 years were considered. An electronic search was made in PubMed, Google Scholar, and EMBASE databases. Studies concerning the use of a combination of enamel matrix derivative (EMD) and Xenograft compared with xenografts alone in periodontitis treatment were selected. Result: 4 studies were included in quantitative analysis after screening by two reviewers. Randomized controlled trials have indicated a signicantly higher pocket reduction and clinical attachment level gain after the application of enamel matrix derivative (EMD) and Xenograft compared with xenografts alone. Conclusion: The use of enamel matrix derivative (EMD) as an adjunct to Xenograft provides signicant results as compared to xenograft alone in intrabony defects of chronic periodontitis patients.
{"title":"EFFECT OF ENAMEL MATRIX PROTEIN DERIVATIVE (EMD) AS AN ADJUNCT TO XENOGRAFT COMPARED TO XENOGRAFT ALONE IN THE TREATMENT OF INTRABONY DEFECTS IN SUBJECTS WITH CHRONIC PERIODONTITIS: A SYSTEMATIC REVIEW.","authors":"Aishwarya Babasaheb Kotkar, Amit Benjamin, Sangeeta Muglikar, Sneha Jethwani, Dhruti Shah","doi":"10.36106/ijsr/9500573","DOIUrl":"https://doi.org/10.36106/ijsr/9500573","url":null,"abstract":"Background: Enamel matrix derivative (EMD) has been widely used in periodontal regenerative treatment and the xenograft biomaterials show\u0000good biocompatibility and osteoconductivity of demineralized bovine bone matrix. So, to evaluate the improvement in clinical outcomes when\u0000Enamel Matrix Protein Derivative is used as an adjunct to Bovine-Derived Xenograft in intrabony defects of chronic periodontitis patients.\u0000Material And Methodology: In this systematic review, randomized controlled trials in subjects with periodontitis in the age group of 25-70 years\u0000were considered. An electronic search was made in PubMed, Google Scholar, and EMBASE databases. Studies concerning the use of a\u0000combination of enamel matrix derivative (EMD) and Xenograft compared with xenografts alone in periodontitis treatment were selected. Result: 4\u0000studies were included in quantitative analysis after screening by two reviewers. Randomized controlled trials have indicated a signicantly higher\u0000pocket reduction and clinical attachment level gain after the application of enamel matrix derivative (EMD) and Xenograft compared with\u0000xenografts alone. Conclusion: The use of enamel matrix derivative (EMD) as an adjunct to Xenograft provides signicant results as compared to\u0000xenograft alone in intrabony defects of chronic periodontitis patients.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"36 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141043649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pooja Srivatsan, Priya Gupta, Shalaka Indap, Amit Gupta
With an incidence rate of as high as 210 cases per 1,00,000 of population, tuberculosis (Tb) is a very common disease in India (1). Primarily, pulmonary involvement is most common, however recently extra pulmonary sites of Tb has also been rapidly increasing. Among extra-pulmonary Tb (EPTB), lymph node Tb is the most common, genital Tb being the second most common affected site (2). Genital Tb affects both the genders equally and causes complications like infertility. It usually affects organs like bladder, prostate, fallopian tubes and testis.
{"title":"TUBERCULOSIS OF TUNICA VAGINALIS OF TESTIS: A CASE REPORT AND REVIEW OF LITERATURE","authors":"Pooja Srivatsan, Priya Gupta, Shalaka Indap, Amit Gupta","doi":"10.36106/ijsr/6407713","DOIUrl":"https://doi.org/10.36106/ijsr/6407713","url":null,"abstract":"With an incidence rate of as high as 210 cases per 1,00,000 of\u0000population, tuberculosis (Tb) is a very common disease in India (1).\u0000Primarily, pulmonary involvement is most common, however recently\u0000extra pulmonary sites of Tb has also been rapidly increasing. Among\u0000extra-pulmonary Tb (EPTB), lymph node Tb is the most common,\u0000genital Tb being the second most common affected site (2). Genital\u0000Tb affects both the genders equally and causes complications like\u0000infertility. It usually affects organs like bladder, prostate, fallopian\u0000tubes and testis.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"2 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141136335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Harshita Debbarma, Anil Kumar, Tarique Jamil Hasan
Background: Traumatic brain injury (TBI) is a growing public health problem worldwide and is a leading cause of death and disability. Hormonal alterations leading to post-traumatic pituitary dysfunction (PTPD) usually become apparent in the rst hours or days after TBI.In this study, we focused on the prevalence of anterior and posterior pituitary hormonal alterations in the acute and chronic post-TBI period in adults. Material &