首页 > 最新文献

International journal of scientific research最新文献

英文 中文
ACCURACY OF COMPUTED TOMOGRAPHY IN CHARACTERISATION OF COLORECTAL LESIONS AS BENIGN OR MALIGNANT AND IN PRE-OP STAGING OF COLORECTAL CARCINOMA WITH HISTOPATHOLOGICAL CORRELATION 计算机断层扫描在确定结直肠病变是良性还是恶性以及结直肠癌术前分期与组织病理学相关性方面的准确性
Pub Date : 2024-05-01 DOI: 10.36106/ijsr/6400251
Deepika Nair, Rinku Mercy Thomas
Objective-To determine the accuracy of Multi Detector CT in characterizing colorectal lesions as benign or malignant - and its correlation withhistopathology by studying bowel wall characteristics. - Methods 55 patients referred to the Department of Radiodiagnosis at a tertiary care centrein Trivandrum for contrast CT abdomen who had abnormal bowel wall thickening on CT. Lesions are classied on CT as benign or malignantbased on bowel wall characteristics of wall thickening and staging is done in case of colorectal carcinoma. The ndings are then compared with thehistopathological diagnosis. Results- Overall, CT had a sensitivity of 94.9%, specicity of 93.8%, Positive Predictive Value of 97.4% and aNegative Predictive Value of 88.2% in the diagnosis of malignant lesions. Accuracy of CT in diagnosing malignant lesions is 94.5%. Positivelikelihood ratio is 15.2. and negative likelihood ratio is 0.05.CT is an excellent modality for tumour (T) staging in colorectal malignancy, as per ourstudy, K=0.806 (excellent agreement).CT, though not highly accurate, can be used for lymph nodal (N) staging in colorectal malignancy, as per ourstudy, K= 0.213 (fair agreement). Conclusion- Due to its high sensitivity and specicity, MDCT is an excellent modality in the diagnosis anddifferentiation of benign and malignant lesions of the colon and rectum,.It offers early detection of colorectal malignancy, provides staging ofmalignancies, helps in detection of metastasis, thereby aiding in the choice of treatment strategy. CT is an excellent modality for tumour (T) stagingin colorectal malignancy, as per our study, K=0.806 (excellent agreement).
目的-通过研究肠壁特征,确定多探测器 CT 将结肠直肠病变定性为良性或恶性的准确性及其与组织病理学的相关性。- 方法 55 名转诊至特里凡得琅市一家三级医疗中心放射诊断部接受腹部对比 CT 检查的患者,这些患者在 CT 上发现肠壁异常增厚。根据肠壁增厚的特征,CT 将病变分为良性和恶性,如果是结直肠癌,则进行分期。然后将  与组织病理学诊断进行比较。结果 - 总体而言,CT 诊断恶性病变的灵敏度为 94.9%,特city 为 93.8%,阳性预测值为 97.4%,阴性预测值为 88.2%。CT 诊断恶性病变的准确率为 94.5%。CT 是结直肠恶性肿瘤(T)分期的极佳方式,根据我们的研究,K=0.806(极好的一致性)。CT 虽然准确性不高,但可用于结直肠恶性肿瘤淋巴结(N)分期,根据我们的研究,K=0.213(一般的一致性)。结论- MDCT 具有高灵敏度和高特异性city,是诊断和鉴别结肠和直肠良恶性病变的绝佳方式。它能早期发现结直肠恶性肿瘤,为恶性肿瘤提供分期,有助于发现转移灶,从而帮助选择治疗策略。CT 是结直肠恶性肿瘤(T)分期的绝佳方式,根据我们的研究,K=0.806(极好的一致性)。
{"title":"ACCURACY OF COMPUTED TOMOGRAPHY IN CHARACTERISATION OF COLORECTAL LESIONS AS BENIGN OR MALIGNANT AND IN PRE-OP STAGING OF COLORECTAL CARCINOMA WITH HISTOPATHOLOGICAL CORRELATION","authors":"Deepika Nair, Rinku Mercy Thomas","doi":"10.36106/ijsr/6400251","DOIUrl":"https://doi.org/10.36106/ijsr/6400251","url":null,"abstract":"Objective-To determine the accuracy of Multi Detector CT in characterizing colorectal lesions as benign or malignant - and its correlation with\u0000histopathology by studying bowel wall characteristics. - Methods 55 patients referred to the Department of Radiodiagnosis at a tertiary care centre\u0000in Trivandrum for contrast CT abdomen who had abnormal bowel wall thickening on CT. Lesions are classied on CT as benign or malignant\u0000based on bowel wall characteristics of wall thickening and staging is done in case of colorectal carcinoma. The ndings are then compared with the\u0000histopathological diagnosis. Results- Overall, CT had a sensitivity of 94.9%, specicity of 93.8%, Positive Predictive Value of 97.4% and a\u0000Negative Predictive Value of 88.2% in the diagnosis of malignant lesions. Accuracy of CT in diagnosing malignant lesions is 94.5%. Positive\u0000likelihood ratio is 15.2. and negative likelihood ratio is 0.05.CT is an excellent modality for tumour (T) staging in colorectal malignancy, as per our\u0000study, K=0.806 (excellent agreement).CT, though not highly accurate, can be used for lymph nodal (N) staging in colorectal malignancy, as per our\u0000study, K= 0.213 (fair agreement). Conclusion- Due to its high sensitivity and specicity, MDCT is an excellent modality in the diagnosis and\u0000differentiation of benign and malignant lesions of the colon and rectum,.It offers early detection of colorectal malignancy, provides staging of\u0000malignancies, helps in detection of metastasis, thereby aiding in the choice of treatment strategy. CT is an excellent modality for tumour (T) staging\u0000in colorectal malignancy, as per our study, K=0.806 (excellent agreement).","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"86 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141037986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EFFECT OF ENAMEL MATRIX PROTEIN DERIVATIVE (EMD) AS AN ADJUNCT TO XENOGRAFT COMPARED TO XENOGRAFT ALONE IN THE TREATMENT OF INTRABONY DEFECTS IN SUBJECTS WITH CHRONIC PERIODONTITIS: A SYSTEMATIC REVIEW. 釉质基质蛋白衍生物(EMD)作为异种牙移植的辅助手段与单独使用异种牙移植治疗慢性牙周炎患者牙槽骨内缺损的效果比较:系统综述。
Pub Date : 2024-05-01 DOI: 10.36106/ijsr/9500573
Aishwarya Babasaheb Kotkar, Amit Benjamin, Sangeeta Muglikar, Sneha Jethwani, Dhruti Shah
Background: Enamel matrix derivative (EMD) has been widely used in periodontal regenerative treatment and the xenograft biomaterials showgood biocompatibility and osteoconductivity of demineralized bovine bone matrix. So, to evaluate the improvement in clinical outcomes whenEnamel Matrix Protein Derivative is used as an adjunct to Bovine-Derived Xenograft in intrabony defects of chronic periodontitis patients.Material And Methodology: In this systematic review, randomized controlled trials in subjects with periodontitis in the age group of 25-70 yearswere considered. An electronic search was made in PubMed, Google Scholar, and EMBASE databases. Studies concerning the use of acombination of enamel matrix derivative (EMD) and Xenograft compared with xenografts alone in periodontitis treatment were selected. Result: 4studies were included in quantitative analysis after screening by two reviewers. Randomized controlled trials have indicated a signicantly higherpocket reduction and clinical attachment level gain after the application of enamel matrix derivative (EMD) and Xenograft compared withxenografts alone. Conclusion: The use of enamel matrix derivative (EMD) as an adjunct to Xenograft provides signicant results as compared toxenograft alone in intrabony defects of chronic periodontitis patients.
背景:釉质基质衍生物(EMD)已被广泛应用于牙周再生治疗,而异种生物材料显示出良好的生物相容性和去矿化牛骨基质的骨传导性。因此,为了评估在慢性牙周炎患者的牙槽骨内缺损中使用伊奈梅尔基质蛋白衍生物作为牛源性异种移植的辅助治疗对临床疗效的改善情况:本系统综述考虑了针对 25-70 岁牙周炎患者的随机对照试验。在 PubMed、Google Scholar 和 EMBASE 数据库中进行了电子检索。选择了关于在牙周炎治疗中使用釉质基质衍生物(EMD)和异种移植体组合与单独使用异种移植体组合的研究。结果:经过两名审稿人的筛选,4 项研究被纳入定量分析。随机对照试验表明,应用釉质基质衍生物(EMD)和Xenograft与单独应用异种牙移植相比,牙周袋的缩小和临床附着水平的提高显著。结论:在慢性牙周炎患者的牙槽骨内缺损中,使用釉质基质衍生物(EMD)作为Xenograft的辅助治疗,与单独使用Xenograft相比,效果显著。
{"title":"EFFECT OF ENAMEL MATRIX PROTEIN DERIVATIVE (EMD) AS AN ADJUNCT TO XENOGRAFT COMPARED TO XENOGRAFT ALONE IN THE TREATMENT OF INTRABONY DEFECTS IN SUBJECTS WITH CHRONIC PERIODONTITIS: A SYSTEMATIC REVIEW.","authors":"Aishwarya Babasaheb Kotkar, Amit Benjamin, Sangeeta Muglikar, Sneha Jethwani, Dhruti Shah","doi":"10.36106/ijsr/9500573","DOIUrl":"https://doi.org/10.36106/ijsr/9500573","url":null,"abstract":"Background: Enamel matrix derivative (EMD) has been widely used in periodontal regenerative treatment and the xenograft biomaterials show\u0000good biocompatibility and osteoconductivity of demineralized bovine bone matrix. So, to evaluate the improvement in clinical outcomes when\u0000Enamel Matrix Protein Derivative is used as an adjunct to Bovine-Derived Xenograft in intrabony defects of chronic periodontitis patients.\u0000Material And Methodology: In this systematic review, randomized controlled trials in subjects with periodontitis in the age group of 25-70 years\u0000were considered. An electronic search was made in PubMed, Google Scholar, and EMBASE databases. Studies concerning the use of a\u0000combination of enamel matrix derivative (EMD) and Xenograft compared with xenografts alone in periodontitis treatment were selected. Result: 4\u0000studies were included in quantitative analysis after screening by two reviewers. Randomized controlled trials have indicated a signicantly higher\u0000pocket reduction and clinical attachment level gain after the application of enamel matrix derivative (EMD) and Xenograft compared with\u0000xenografts alone. Conclusion: The use of enamel matrix derivative (EMD) as an adjunct to Xenograft provides signicant results as compared to\u0000xenograft alone in intrabony defects of chronic periodontitis patients.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"36 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141043649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
TUBERCULOSIS OF TUNICA VAGINALIS OF TESTIS: A CASE REPORT AND REVIEW OF LITERATURE 睾丸阴道壁结核:病例报告和文献综述
Pub Date : 2024-05-01 DOI: 10.36106/ijsr/6407713
Pooja Srivatsan, Priya Gupta, Shalaka Indap, Amit Gupta
With an incidence rate of as high as 210 cases per 1,00,000 ofpopulation, tuberculosis (Tb) is a very common disease in India (1).Primarily, pulmonary involvement is most common, however recentlyextra pulmonary sites of Tb has also been rapidly increasing. Amongextra-pulmonary Tb (EPTB), lymph node Tb is the most common,genital Tb being the second most common affected site (2). GenitalTb affects both the genders equally and causes complications likeinfertility. It usually affects organs like bladder, prostate, fallopiantubes and testis.
在印度,肺结核(Tb)的发病率高达每 100,000 人中 210 例,是一种非常常见的疾病(1)。在肺外结核(EPTB)中,淋巴结结核最为常见,生殖器结核则是第二大常见受累部位(2)。生殖器结核对男女两性的影响相同,并导致不育等并发症。它通常影响膀胱、前列腺、输卵管和睾丸等器官。
{"title":"TUBERCULOSIS OF TUNICA VAGINALIS OF TESTIS: A CASE REPORT AND REVIEW OF LITERATURE","authors":"Pooja Srivatsan, Priya Gupta, Shalaka Indap, Amit Gupta","doi":"10.36106/ijsr/6407713","DOIUrl":"https://doi.org/10.36106/ijsr/6407713","url":null,"abstract":"With an incidence rate of as high as 210 cases per 1,00,000 of\u0000population, tuberculosis (Tb) is a very common disease in India (1).\u0000Primarily, pulmonary involvement is most common, however recently\u0000extra pulmonary sites of Tb has also been rapidly increasing. Among\u0000extra-pulmonary Tb (EPTB), lymph node Tb is the most common,\u0000genital Tb being the second most common affected site (2). Genital\u0000Tb affects both the genders equally and causes complications like\u0000infertility. It usually affects organs like bladder, prostate, fallopian\u0000tubes and testis.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"2 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141136335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PREVALENCE OF PITUITARY DYSFUNCTION IN MODERATE-TO-SEVERE TRAUMATIC BRAIN INJURY IN ADULTS: A PROSPECTIVE STUDY. 中重度脑外伤成人垂体功能障碍的发病率:一项前瞻性研究。
Pub Date : 2024-05-01 DOI: 10.36106/ijsr/5807019
Harshita Debbarma, Anil Kumar, Tarique Jamil Hasan
Background: Traumatic brain injury (TBI) is a growing public health problem worldwide and is a leading cause of death and disability. Hormonalalterations leading to post-traumatic pituitary dysfunction (PTPD) usually become apparent in the rst hours or days after TBI.In this study, wefocused on the prevalence of anterior and posterior pituitary hormonal alterations in the acute and chronic post-TBI period in adults. Material &Method: The study design is a prospective study done in RIMS, Ranchi from March 2021-March 2023. Patients of TBI who were fullling ourinclusion criteria were randomly selected. All pituitary hormonal assessmentwas done both in the acute phase (within 14 days of post-TBI) andchronic phase (1 month, 3 months & 6 months post-TBI). The outcome of patients was analyzed by Modied Rankin Scale. Result: Mean ± SD(range) age at the time of TBI in the 80 patients (62 Male:18 Female) was 40.24 ± 16.77 (18-65) years with moderate TBI (GCS 9-12) in 59(73.75%) and severe TBI (GCS < 8) in 29 (36.25%). RTA was the most frequent cause, occurring in 83.75% of patientsDuring acute phase 16patients (25%) are found having AI with serum cortisol level 179 ± 98.25nmol/L (< -2 SD). 10 out of 80 patients were found to have GHD(IGF-1 <-2SD) at the end of 3 months & 6 months post-TBI.Presence of DI was seen in 10/80 (12.5% of patients) which is identied around 13 ±4.52 days. Hypothyroidism was seen in 5% and hypogonadism in 2.5% of study population. Conclusion: Despite the publication of several caseseries, the true incidence of PTHPremains a matter of considerable debate with divergent rates reported between centers. Acoordinated approachby neurosurgeons, endocrinologists, and the neurorehabilitation unit is fully recommended to provide adequate care to these patients.
背景:创伤性脑损伤(TBI)是全球日益严重的公共卫生问题,也是导致死亡和残疾的主要原因之一。导致创伤后垂体功能障碍(PTPD)的激素变化通常在创伤性脑损伤(TBI)后数小时或数天内变得明显。在本研究中,我们重点研究了创伤性脑损伤后急性期和慢性期成人垂体前叶和后叶激素变化的发生率。材料与方法:研究设计是一项前瞻性研究,于 2021 年 3 月至 2023 年 3 月在兰契的 RIMS 进行。随机选取符合我们的纳入标准的创伤后脑损伤患者。所有垂体激素评估均在急性期(创伤后 14 天内)和慢性期(创伤后 1 个月、3 个月和 6 个月)进行。患者的预后通过莫迪ed Rankin Scale进行分析。结果:80 名患者(62 名男性:18 名女性)发生创伤性脑损伤时的平均年龄为 40.24 ± 16.77(18-65)岁,其中 59 人(73.75%)为中度创伤性脑损伤(GCS 9-12),29 人(36.25%)为重度创伤性脑损伤(GCS < 8)。在急性期,发现 16 名患者(25%)有 AI,血清皮质醇水平为 179 ± 98.25nmol/L(< -2 SD)。在创伤后 3 个月和 6 个月结束时,80 名患者中有 10 人被发现患有 GHD(IGF-1 <-2SD)。10/80(12.5% 的患者)在 13 ±4.52 天左右被发现患有 DI。5%的研究对象患有甲状腺功能减退症,2.5%的研究对象患有性腺功能减退症。结论:尽管有多个病例发表,但PTHP的真实发病率仍是一个颇具争议的问题,不同中心的报告率也不尽相同。我们建议神经外科医生、内分泌科医生和神经康复科采取协调一致的方法,为这些患者提供充分的治疗。
{"title":"PREVALENCE OF PITUITARY DYSFUNCTION IN MODERATE-TO-SEVERE TRAUMATIC BRAIN INJURY IN ADULTS: A PROSPECTIVE STUDY.","authors":"Harshita Debbarma, Anil Kumar, Tarique Jamil Hasan","doi":"10.36106/ijsr/5807019","DOIUrl":"https://doi.org/10.36106/ijsr/5807019","url":null,"abstract":"Background: Traumatic brain injury (TBI) is a growing public health problem worldwide and is a leading cause of death and disability. Hormonal\u0000alterations leading to post-traumatic pituitary dysfunction (PTPD) usually become apparent in the rst hours or days after TBI.In this study, we\u0000focused on the prevalence of anterior and posterior pituitary hormonal alterations in the acute and chronic post-TBI period in adults. Material &\u0000Method: The study design is a prospective study done in RIMS, Ranchi from March 2021-March 2023. Patients of TBI who were fullling our\u0000inclusion criteria were randomly selected. All pituitary hormonal assessmentwas done both in the acute phase (within 14 days of post-TBI) and\u0000chronic phase (1 month, 3 months & 6 months post-TBI). The outcome of patients was analyzed by Modied Rankin Scale. Result: Mean ± SD\u0000(range) age at the time of TBI in the 80 patients (62 Male:18 Female) was 40.24 ± 16.77 (18-65) years with moderate TBI (GCS 9-12) in 59\u0000(73.75%) and severe TBI (GCS < 8) in 29 (36.25%). RTA was the most frequent cause, occurring in 83.75% of patientsDuring acute phase 16\u0000patients (25%) are found having AI with serum cortisol level 179 ± 98.25nmol/L (< -2 SD). 10 out of 80 patients were found to have GHD\u0000(IGF-1 <-2SD) at the end of 3 months & 6 months post-TBI.Presence of DI was seen in 10/80 (12.5% of patients) which is identied around 13 ±\u00004.52 days. Hypothyroidism was seen in 5% and hypogonadism in 2.5% of study population. Conclusion: Despite the publication of several case\u0000series, the true incidence of PTHPremains a matter of considerable debate with divergent rates reported between centers. Acoordinated approach\u0000by neurosurgeons, endocrinologists, and the neurorehabilitation unit is fully recommended to provide adequate care to these patients.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"37 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141143480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
UNVEILING ACCELERATED HYPERTENSION: A CASE STUDY OF POSTSPLENECTOMY HYPERTENSION IN PREVIOUSLY NORMOTENSIVE INDIVIDUAL WITH THORACOABDOMINAL TRAUMA 揭开加速性高血压的神秘面纱:对以前血压正常但有胸腹部创伤的患者进行脾切除术后高血压病例研究
Pub Date : 2024-05-01 DOI: 10.36106/ijsr/7203657
Prakash Narayan Gupta, Anush Anil Kumar
Splenectomy often associated with multiple vascular complications. We present a case of Road trafc accident(RTA) for which splenectomy wasdone ,grade 3 splenic injury scale by American Association for Surgery of Trauma(AAST) that resulted in accelerated hypertension in a previouslynormotensive 68yrs old male. Patient was managed aggressively with IV anti-hypertensive. On follow up patient was normotensive.
脾脏切除术通常与多种血管并发症有关。我们介绍了一例道路交通c 事故(RTA)的脾脏切除术,根据美国创伤外科协会(AAST)的标准,脾脏损伤等级为 3 级,这导致一名之前血压正常的 68 岁男性加速患上高血压。患者接受了静脉注射抗高血压药物的积极治疗。随访时患者血压正常。
{"title":"UNVEILING ACCELERATED HYPERTENSION: A CASE STUDY OF POSTSPLENECTOMY HYPERTENSION IN PREVIOUSLY NORMOTENSIVE INDIVIDUAL WITH THORACOABDOMINAL TRAUMA","authors":"Prakash Narayan Gupta, Anush Anil Kumar","doi":"10.36106/ijsr/7203657","DOIUrl":"https://doi.org/10.36106/ijsr/7203657","url":null,"abstract":"Splenectomy often associated with multiple vascular complications. We present a case of Road trafc accident(RTA) for which splenectomy was\u0000done ,grade 3 splenic injury scale by American Association for Surgery of Trauma(AAST) that resulted in accelerated hypertension in a previously\u0000normotensive 68yrs old male. Patient was managed aggressively with IV anti-hypertensive. On follow up patient was normotensive.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"43 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141043335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ROLE OF CT UROGRAPHY IN EVALUATION OF PATIENTS WITH OBSTRUCTIVE UROPATHY: A PROSPECTIVE STUDY OF 50 PATIENTS IN A URBAN TERTIARY CARE HOSPITAL CT 尿路造影在评估梗阻性尿路病患者中的作用:对一家城市三级医院 50 名患者的前瞻性研究
Pub Date : 2024-05-01 DOI: 10.36106/ijsr/9802040
Sumit Pawar
Introduction: Obstructive uropathy is a relatively common clinical problem which if not treated timely can lead to irreversible renal damage.Therefore, accurate diagnosis is important for timely management. The purpose of present study is t Aim: o assess role Multidetector ComputedTomography (MDCT) urography in evaluation of obstructive uropathy. This prospective study was condu Materials and Methods: cted on 50consecutive subjects presenting with evidence of unilateral or bilateral hydronephrosis and who were referred for CT urography for detection ofsite and cause obstruction. Out of 50 subjects, urinary obstruction was unilateral in 45 subjects ( Results: 90%) in our study. Only 5 subjects (10%)had bilateral urinary obstruction. Most common cause of urinary obstruction was urinary tract calculi which accounted for a total of 41 subjects(82%) (74 % had unilateral obstruction and 8% had bilateral urinary obstruction). Out of these, 9 subjects had calculi in the renal pelvis and 32subjects had ureteric calculi. Second most common cause was urinary bladder masses which were causes of unilateral obstruction in 4 subjects(8%) and bilateral obstruction in 1 subject (2%). Other less common causes of urinary obstruction were PUJ obstruction in 2 subjects (4%) &ureteric stricture 2 subjects (4%) MDCT urography is very useful for complete evaluation of obstruc Conclusion: tive uropathy and allows rapiddetection of level and cause of obstruction which is critical for timely and effective management.
简介梗阻性尿路病是一种比较常见的临床问题,如果治疗不及时,会导致不可逆转的肾损伤。本研究旨在评估多载体计算机断层成像(MDCT)尿路造影术在评估梗阻性尿路病变中的作用。这项前瞻性研究的对象是 50 名连续出现单侧或双侧肾积水的受试者,这些受试者被转诊接受 CT 尿路造影检查,以确定梗阻部位和原因。在 50 名受试者中,45 名受试者的尿路梗阻是单侧的(结果:90%)。只有 5 名受试者(10%)出现双侧尿路梗阻。最常见的尿路梗阻原因是尿路结石,共占 41 名受试者(82%)(74%为单侧梗阻,8%为双侧梗阻)。其中,9 名受试者的结石位于肾盂,32 名受试者的结石位于输尿管。其次最常见的原因是膀胱肿块,4 名受试者(8%)的膀胱肿块导致单侧尿路梗阻,1 名受试者(2%)的膀胱肿块导致双侧尿路梗阻。其他较少见的尿路梗阻原因包括 PUJ 梗阻 2 例(4%)和输尿管狭窄 2 例(4%)。 MDCT 尿路造影对于全面评估梗阻性尿病非常有用,可快速检测梗阻程度和原因,这对于及时有效的治疗至关重要。
{"title":"ROLE OF CT UROGRAPHY IN EVALUATION OF PATIENTS WITH OBSTRUCTIVE UROPATHY: A PROSPECTIVE STUDY OF 50 PATIENTS IN A URBAN TERTIARY CARE HOSPITAL","authors":"Sumit Pawar","doi":"10.36106/ijsr/9802040","DOIUrl":"https://doi.org/10.36106/ijsr/9802040","url":null,"abstract":"Introduction: Obstructive uropathy is a relatively common clinical problem which if not treated timely can lead to irreversible renal damage.\u0000Therefore, accurate diagnosis is important for timely management. The purpose of present study is t Aim: o assess role Multidetector Computed\u0000Tomography (MDCT) urography in evaluation of obstructive uropathy. This prospective study was condu Materials and Methods: cted on 50\u0000consecutive subjects presenting with evidence of unilateral or bilateral hydronephrosis and who were referred for CT urography for detection of\u0000site and cause obstruction. Out of 50 subjects, urinary obstruction was unilateral in 45 subjects ( Results: 90%) in our study. Only 5 subjects (10%)\u0000had bilateral urinary obstruction. Most common cause of urinary obstruction was urinary tract calculi which accounted for a total of 41 subjects\u0000(82%) (74 % had unilateral obstruction and 8% had bilateral urinary obstruction). Out of these, 9 subjects had calculi in the renal pelvis and 32\u0000subjects had ureteric calculi. Second most common cause was urinary bladder masses which were causes of unilateral obstruction in 4 subjects\u0000(8%) and bilateral obstruction in 1 subject (2%). Other less common causes of urinary obstruction were PUJ obstruction in 2 subjects (4%) &\u0000ureteric stricture 2 subjects (4%) MDCT urography is very useful for complete evaluation of obstruc Conclusion: tive uropathy and allows rapid\u0000detection of level and cause of obstruction which is critical for timely and effective management.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"7 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141023552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A RARE CASE OF DOUBLE SVC 罕见的双重服务
Pub Date : 2024-05-01 DOI: 10.36106/ijsr/3902352
Sindhuja Ramakrishnan, Daxa Chavada, Laxmikant Bamaniya
Various anomalies in the development of great thoracic veins of the embryo can be found incidentally in a normal adult. Normally the superior venacava is a single vascular structure formed by the union of right and left brachiocephalic veins which are in turn formed by the union ofcorresponding internal jugular and subclavian veins, draining the head and neck as well as the superior extremity.1 A review of the literature since1887 indicates that this is an addition to 216 cases of double superior venae cava in cadavers.2
胚胎大胸腔静脉发育过程中的各种异常都可能在正常成人身上偶然发现。正常情况下,上腔静脉是由左右肱静脉联合形成的单一血管结构,而左右肱静脉又是由相应的颈内静脉和锁骨下静脉联合形成的,为头颈部和上肢引流。
{"title":"A RARE CASE OF DOUBLE SVC","authors":"Sindhuja Ramakrishnan, Daxa Chavada, Laxmikant Bamaniya","doi":"10.36106/ijsr/3902352","DOIUrl":"https://doi.org/10.36106/ijsr/3902352","url":null,"abstract":"Various anomalies in the development of great thoracic veins of the embryo can be found incidentally in a normal adult. Normally the superior vena\u0000cava is a single vascular structure formed by the union of right and left brachiocephalic veins which are in turn formed by the union of\u0000corresponding internal jugular and subclavian veins, draining the head and neck as well as the superior extremity.1 A review of the literature since\u00001887 indicates that this is an addition to 216 cases of double superior venae cava in cadavers.2","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"2004 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141027405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PROGNOSTIC SIGNIFICANCE OF SERUM CREATINE PHOSPHOKINASE LEVELS IN ORGANOPHOSPHOROUS POISONING : AN OBSERVATIONAL STUDY IN A TERTIARY CARE HOSPITAL 有机磷中毒患者血清肌酸磷酸激酶水平的预后意义:在一家三级医院进行的观察研究
Pub Date : 2024-05-01 DOI: 10.36106/ijsr/4704499
Rokkam Mamatha, K. Hanuma Kumar M.D
Background:organophosphorous poisoning is the major cause of mortality and morbidity in developing countries like india. It is the mostcommonly used insecticide in India and easily available. Erythrocyte cholinesterase and butyryl cholinesterase are markers for assessing theseverity of OPpoisoning, but they are costly and not available at all centers. This study was done to assess and nd out the correlation of CPK levelswith severity of OPpoisoning Aims & Objectives :To assess serum creatine phosphokinase (CPK) level in OPpoisoning To nd out the correlationof serum creatine phosphokinase (CPK) level With the severity of OPpoisoning Materials And Methods: AHospital-based cross-sectional studywas conducted in the Department of General Medicine, Santhiram medical college, and the general hospital for six months. A total of 100 caseswith OP poisoning admitted to wards &ICU who satisfy the inclusion criteria were taken in to study. Results: Out of 100 patients 63 % were malesand 37 % were females. Majority were in age group 19 -30 years. Methyl parathion was the most commonly used compound. Most of the casespresented with mild op poisoning. Serial measurement of serum CPK levels showed signicant correlation with the severity of acute OPpoisoningpatients. Conclusion: High initial serum CPK levels is associated with severe degree of poisoning and is associated with complications andmortality. CPK may be considered as a prognostic marker of OPC intoxication since it enables the early recognition of severity and also helps toidentify those at risk of developing the delayed complications of OPC poisoning
背景:在印度等发展中国家,有机磷中毒是导致死亡和发病的主要原因。它是印度最常用的杀虫剂,而且很容易获得。红细胞胆碱酯酶和丁酰胆碱酯酶是评估有机磷中毒严重程度的标志物,但它们价格昂贵,而且并非所有中心都能提供。本研究旨在评估血清肌酸磷酸激酶(CPK)水平与 OP 中毒严重程度的相关性,并 。 目的和方法:在 Santhiram 医学院全科医学系和综合医院进行了为期 6 个月的医院横断面研究。共有 100 例符合纳入标准的 OP 中毒患者入住病房和重症监护室。研究结果100 名患者中,63% 为男性,37% 为女性。大多数患者的年龄在 19-30 岁之间。甲基对硫磷是最常用的化合物。大多数病例表现为轻度 OP 中毒。血清 CPK 水平的连续测量结果显示与急性 OP 中毒患者的严重程度有明显。结论:初始血清 CPK 水平高与中毒程度严重有关,并与并发症和死亡有关。CPK 可被视为 OPC 中毒的预后标志物,因为它能够及早识别中毒的严重程度,还有助于识别那些有可能患上 OPC 中毒迟发性并发症的患者。
{"title":"PROGNOSTIC SIGNIFICANCE OF SERUM CREATINE PHOSPHOKINASE LEVELS IN ORGANOPHOSPHOROUS POISONING : AN OBSERVATIONAL STUDY IN A TERTIARY CARE HOSPITAL","authors":"Rokkam Mamatha, K. Hanuma Kumar M.D","doi":"10.36106/ijsr/4704499","DOIUrl":"https://doi.org/10.36106/ijsr/4704499","url":null,"abstract":"Background:organophosphorous poisoning is the major cause of mortality and morbidity in developing countries like india. It is the most\u0000commonly used insecticide in India and easily available. Erythrocyte cholinesterase and butyryl cholinesterase are markers for assessing the\u0000severity of OPpoisoning, but they are costly and not available at all centers. This study was done to assess and nd out the correlation of CPK levels\u0000with severity of OPpoisoning Aims & Objectives :To assess serum creatine phosphokinase (CPK) level in OPpoisoning To nd out the correlation\u0000of serum creatine phosphokinase (CPK) level With the severity of OPpoisoning Materials And Methods: AHospital-based cross-sectional study\u0000was conducted in the Department of General Medicine, Santhiram medical college, and the general hospital for six months. A total of 100 cases\u0000with OP poisoning admitted to wards &ICU who satisfy the inclusion criteria were taken in to study. Results: Out of 100 patients 63 % were males\u0000and 37 % were females. Majority were in age group 19 -30 years. Methyl parathion was the most commonly used compound. Most of the cases\u0000presented with mild op poisoning. Serial measurement of serum CPK levels showed signicant correlation with the severity of acute OPpoisoning\u0000patients. Conclusion: High initial serum CPK levels is associated with severe degree of poisoning and is associated with complications and\u0000mortality. CPK may be considered as a prognostic marker of OPC intoxication since it enables the early recognition of severity and also helps to\u0000identify those at risk of developing the delayed complications of OPC poisoning","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"6 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141024232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
OCULAR SIDE EFFECTS OF MISUSE OF PROPARACAINE HYDROCHLORIDE 滥用盐酸丙卡因对眼睛的副作用
Pub Date : 2024-05-01 DOI: 10.36106/ijsr/0505728
Kritika Kritika, Kanav Gupta, Brij K Gupta, Isha Gupta
Public health is at risk because of the emerging trend of misuse and abuse of medications. With time there has been a trend of ophthalmicmedication misuse. The difference between misuse and abuse is how they affect people's ability to feel good, unwind, have hallucinations, and havefewer symptoms of depression. Topical anaesthetic is commonly used by ophthalmologists in clinical practice, and in emergencies to removecorneal foreign bodies. In ophthalmology, proparacaine hydrochloride, also known as 2-(diethylamino) ethyl 3-amino-4-propoxybenzoatehydrochloride, is a common choice for topical anaesthesia. But these drugs are rarely prescribed to patients because of their easy availability theirmisuse is increasing tremendously leading to sight-threatening side effects. This article highlights the side effects and properties of proparacainehydrochloride.
误用和滥用药物的新趋势危及公众健康。随着时间的推移,眼科药物的滥用已成为一种趋势。误用和滥用的区别在于它们如何影响人们的感觉、放松、幻觉和抑郁症状。眼科医生在临床实践中和紧急情况下通常使用局部麻醉剂来清除角膜异物。在眼科中,盐酸丙美卡因(又称 2-(二乙基氨基)乙基 3-氨基-4-丙氧基苯甲酸盐酸盐)是局部麻醉的常用药物。但由于这些药物很容易买到,因此很少被开给患者使用,其滥用现象也在大幅增加,导致了危及视力的副作用。本文重点介绍盐酸丙美卡因的副作用和特性。
{"title":"OCULAR SIDE EFFECTS OF MISUSE OF PROPARACAINE HYDROCHLORIDE","authors":"Kritika Kritika, Kanav Gupta, Brij K Gupta, Isha Gupta","doi":"10.36106/ijsr/0505728","DOIUrl":"https://doi.org/10.36106/ijsr/0505728","url":null,"abstract":"Public health is at risk because of the emerging trend of misuse and abuse of medications. With time there has been a trend of ophthalmic\u0000medication misuse. The difference between misuse and abuse is how they affect people's ability to feel good, unwind, have hallucinations, and have\u0000fewer symptoms of depression. Topical anaesthetic is commonly used by ophthalmologists in clinical practice, and in emergencies to remove\u0000corneal foreign bodies. In ophthalmology, proparacaine hydrochloride, also known as 2-(diethylamino) ethyl 3-amino-4-propoxybenzoate\u0000hydrochloride, is a common choice for topical anaesthesia. But these drugs are rarely prescribed to patients because of their easy availability their\u0000misuse is increasing tremendously leading to sight-threatening side effects. This article highlights the side effects and properties of proparacaine\u0000hydrochloride.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"51 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141038638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
TRANSFORMATIVE APPLICATIONS OF ARTIFICIAL INTELLIGENCE IN PERIODONTAL RESEARCH: A STRATEGIC AND COMPREHENSIVE OVERVIEW 人工智能在牙周研究中的变革性应用:战略性全面概述
Pub Date : 2024-05-01 DOI: 10.36106/ijsr/0604914
Neelam Das, P. Addanki
The integration of Articial Intelligence (AI) into periodontal research has revolutionized methodologies, enhancing efciency, accuracy, and thebreadth of scientic inquiry. This comprehensive review details AI tools that optimize stages from topic selection through publication, highlightingtheir impact on advancing clinical practices and research in periodontology.
人工cial Intelligence(AI)与牙周研究的结合彻底改变了研究方法,提高了科学c 探究的效率、准确性和广度。这篇综合评论详细介绍了从选题到发表的各个优化阶段的人工智能工具,强调了它们对推进牙周病学临床实践和研究的影响。
{"title":"TRANSFORMATIVE APPLICATIONS OF ARTIFICIAL INTELLIGENCE IN PERIODONTAL RESEARCH: A STRATEGIC AND COMPREHENSIVE OVERVIEW","authors":"Neelam Das, P. Addanki","doi":"10.36106/ijsr/0604914","DOIUrl":"https://doi.org/10.36106/ijsr/0604914","url":null,"abstract":"The integration of Articial Intelligence (AI) into periodontal research has revolutionized methodologies, enhancing efciency, accuracy, and the\u0000breadth of scientic inquiry. This comprehensive review details AI tools that optimize stages from topic selection through publication, highlighting\u0000their impact on advancing clinical practices and research in periodontology.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"2011 32","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141027384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
International journal of scientific research
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1