The diagnosis of genital ulcers remains a challenge in clinical practice. Lipschutz ulcer is a non-sexually transmitted rare and probably underdiagnosed condition. It is characterized by the sudden onset of painful vulvar ulcerations often preceded by febrile episode
{"title":"CASE REPORT: LIPSCHUTZ ULCER","authors":"Dhanashree Bhide, Garavi Talati, Monal Sadhwani","doi":"10.36106/ijsr/0304721","DOIUrl":"https://doi.org/10.36106/ijsr/0304721","url":null,"abstract":"The diagnosis of genital ulcers remains a challenge in clinical practice. Lipschutz ulcer is a non-sexually transmitted rare and probably\u0000underdiagnosed condition. It is characterized by the sudden onset of painful vulvar ulcerations often preceded by febrile episode","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"117 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141033366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zenker's diverticulum is a rare disorder characterized by the herniation of the post-pharyngeal wall through the Killian's triangle, located between the inferior constrictor muscle and the cricopharyngeus muscle. Surgical intervention used to be the primary treatment for Zenker's diverticulum, despite its high morbidity and mortality rates. In recent years, Z-POEM, a technique utilizing third-space endoscopy, has emerged, specically tailored for Zenker's diverticulum. It is a relatively new addition to the natural orice transluminal endoscopic surgeries (NOTES). Usually carried out in endoscopy suites, a crucial step in the procedure involves creating a submucosal tunnel in the esophageal wall and the continuous insufation of CO2 can inadvertently lead to complications such as subcutaneous emphysema, capnomediastinum, capnothorax, or even capnoperitoneum, due to tracking of CO2 in surrounding tissues. Anesthesiologists face the challenge of not only administering anesthesia in a remote location, but also promptly detecting and managing these complications. Here, we outline the effective anesthetic management in the case of an adult male diagnosed with Zenker's Diverticulum who underwent Z-POEM procedure under General Anesthesia.
{"title":"ANAESTHETIC MANAGEMENT OF A CASE OF ZENKER'S DIVERTICULUM POSTED FOR Z-POEM UNDER GENERAL ANAESTHESIA","authors":"Divya J. Rohra, Shantanu B. Kulkarni","doi":"10.36106/ijsr/1306482","DOIUrl":"https://doi.org/10.36106/ijsr/1306482","url":null,"abstract":"Zenker's diverticulum is a rare disorder characterized by the herniation of the post-pharyngeal wall through the Killian's triangle, located between\u0000the inferior constrictor muscle and the cricopharyngeus muscle. Surgical intervention used to be the primary treatment for Zenker's diverticulum,\u0000despite its high morbidity and mortality rates. In recent years, Z-POEM, a technique utilizing third-space endoscopy, has emerged, specically\u0000tailored for Zenker's diverticulum. It is a relatively new addition to the natural orice transluminal endoscopic surgeries (NOTES). Usually carried\u0000out in endoscopy suites, a crucial step in the procedure involves creating a submucosal tunnel in the esophageal wall and the continuous insufation\u0000of CO2 can inadvertently lead to complications such as subcutaneous emphysema, capnomediastinum, capnothorax, or even capnoperitoneum,\u0000due to tracking of CO2 in surrounding tissues. Anesthesiologists face the challenge of not only administering anesthesia in a remote location, but\u0000also promptly detecting and managing these complications. Here, we outline the effective anesthetic management in the case of an adult male\u0000diagnosed with Zenker's Diverticulum who underwent Z-POEM procedure under General Anesthesia.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"18 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141133228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: This study investigates the association of dry eye disease (DED) with dyslipidemia. The study also assessed the association of visual display terminal (VDT) and DED in patients with dyslipidemia. The meibomian gland dysfunction (MGD) in DED in patients with dyslipidemia was also studied. In the OPD, 60 patients aged 20-60 years with dyslipidemia were studied. After obtaining i Methods: nformed consent, medical history, and direct interviews using a questionnaire, emphasis was placed on dry eye history before applying the DEEP score. Assessments included VDT use, visual acuity, slit lamp examination for ocular allergy signs, and meibomian gland dysfunction degree. Diagnostic tests (Tear break up time (tBUT), Fluorescein staining, Schirmer's test) determined dry eye grading. Patients were categorized by gender and dry eye status. Serum lipid levels were analyzed to establish the dyslipidemia-DED association. Dyslipidemia criteria included elevated cholesterol, triglycerides, low-density lipoprotein (LDL), and low high-density lipoprotein (HDL) levels. In women, a signicant associatio Results And Findings: n exists between DED and dyslipidemia (p < 0.001), with total cholesterol showing notable relevance, particularly in women. The correlation between dyslipidemia and DED is more prominent among women than men. There was a major difference between the VDT usage in patients with and without DED. Additionally, a substantial difference in MGD is evident between DED and non-DED patients (p = 0.001). Findings reveal a robust Conclusion: association between DED progression and dyslipidemia in women. Patient education on dry eye and ophthalmologists diagnosing dyslipidemia can prevent blindness and cardiovascular disease. t-BUT is affected signicantly among VDT users shows that tear lm becomes unstable by their usage, hence helps in nding the actual correlation of dry eye with the use of VDT. MGD demonstrates statistical signicance (p = 0.001), leading to tear lm alterations, eye irritation, inammation, and ocular surface disease.
{"title":"A STUDY ON THE ASSOCIATION OF DRY EYE WITH DYSLIPIDEMIA","authors":"Sonali Agrawal, Nupur Suman","doi":"10.36106/ijsr/7906393","DOIUrl":"https://doi.org/10.36106/ijsr/7906393","url":null,"abstract":"Aim: This study investigates the association of dry eye disease (DED) with dyslipidemia. The study also assessed the association of visual display\u0000terminal (VDT) and DED in patients with dyslipidemia. The meibomian gland dysfunction (MGD) in DED in patients with dyslipidemia was also\u0000studied. In the OPD, 60 patients aged 20-60 years with dyslipidemia were studied. After obtaining i Methods: nformed consent, medical history,\u0000and direct interviews using a questionnaire, emphasis was placed on dry eye history before applying the DEEP score. Assessments included VDT\u0000use, visual acuity, slit lamp examination for ocular allergy signs, and meibomian gland dysfunction degree. Diagnostic tests (Tear break up time (tBUT), Fluorescein staining, Schirmer's test) determined dry eye grading. Patients were categorized by gender and dry eye status. Serum lipid levels\u0000were analyzed to establish the dyslipidemia-DED association. Dyslipidemia criteria included elevated cholesterol, triglycerides, low-density\u0000lipoprotein (LDL), and low high-density lipoprotein (HDL) levels. In women, a signicant associatio Results And Findings: n exists between\u0000DED and dyslipidemia (p < 0.001), with total cholesterol showing notable relevance, particularly in women. The correlation between dyslipidemia\u0000and DED is more prominent among women than men. There was a major difference between the VDT usage in patients with and without DED.\u0000Additionally, a substantial difference in MGD is evident between DED and non-DED patients (p = 0.001). Findings reveal a robust Conclusion:\u0000association between DED progression and dyslipidemia in women. Patient education on dry eye and ophthalmologists diagnosing dyslipidemia\u0000can prevent blindness and cardiovascular disease. t-BUT is affected signicantly among VDT users shows that tear lm becomes unstable by their\u0000usage, hence helps in nding the actual correlation of dry eye with the use of VDT. MGD demonstrates statistical signicance (p = 0.001), leading\u0000to tear lm alterations, eye irritation, inammation, and ocular surface disease.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"113 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141135468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sebaceoma is a benign adnexal neoplasm showing sebaceous differentiation. This report details a case of a 41-year-old male presented to OPD with complaints of a raised lesion over scalp for 6 months. Excision biopsy was done and sent to our histopathology lab for denitive diagnosis by the clinician with the differential diagnosis of solitary trichoepithelioma. Histopathology showed mature sebocytes and greater than 50% of the tumour cells were basalaoid cells which is consistent with sebaceoma. Sebaceomas are rare skin adnexal neoplasms. It may be associated with Muir-Torre syndrome. It is characterised by multiple rounded cellular lobules and microcystic spaces predominantly composed of immature sebocytes admixed with mature sebocytes.
{"title":"SEBACEOMA-A CASE REPORT","authors":"Vinodini. S, T. J, S. B","doi":"10.36106/ijsr/7102778","DOIUrl":"https://doi.org/10.36106/ijsr/7102778","url":null,"abstract":"Sebaceoma is a benign adnexal neoplasm showing sebaceous differentiation. This report details a case of a 41-year-old male presented to OPD with\u0000complaints of a raised lesion over scalp for 6 months. Excision biopsy was done and sent to our histopathology lab for denitive diagnosis by the\u0000clinician with the differential diagnosis of solitary trichoepithelioma. Histopathology showed mature sebocytes and greater than 50% of the tumour\u0000cells were basalaoid cells which is consistent with sebaceoma. Sebaceomas are rare skin adnexal neoplasms. It may be associated with Muir-Torre\u0000syndrome. It is characterised by multiple rounded cellular lobules and microcystic spaces predominantly composed of immature sebocytes\u0000admixed with mature sebocytes.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"15 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141046536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Priya Gupta, Vishakha Kalikar, Prasad Bhukebag, Roy Patankar
Mucocele of the appendix occurs due to obstruction of lumen of appendix resulting in abnormal accumulation of mucous in the lumen, giving the appendix an enlarged appearance with thinned out wall. Preoperative clinical diagnosis may be challenging due to non-specic clinical manifestations of the disease or may mimic acute appendicitis. Radiological imaging is essential for diagnosis. When diagnosed preoperatively, it is always treated by surgery which depends on size and integrity of the appendix base and on the histology of the lesion. During surgery, care should be taken to avoid spillage of its contents into the abdomen which may lead to pseudomyxoma peritonei (PP), which has very poor prognosis.
{"title":"EVOLUTION OF MANAGEMENT OF MUCOCELE OF APPENDIX OVER TIMECASE SERIES AND REVIEW OF LITERATURE","authors":"Priya Gupta, Vishakha Kalikar, Prasad Bhukebag, Roy Patankar","doi":"10.36106/ijsr/6907828","DOIUrl":"https://doi.org/10.36106/ijsr/6907828","url":null,"abstract":"Mucocele of the appendix occurs due to obstruction of lumen of\u0000appendix resulting in abnormal accumulation of mucous in the lumen,\u0000giving the appendix an enlarged appearance with thinned out wall.\u0000Preoperative clinical diagnosis may be challenging due to non-specic\u0000clinical manifestations of the disease or may mimic acute appendicitis.\u0000Radiological imaging is essential for diagnosis. When diagnosed preoperatively, it is always treated by surgery which depends on size and\u0000integrity of the appendix base and on the histology of the lesion.\u0000During surgery, care should be taken to avoid spillage of its contents\u0000into the abdomen which may lead to pseudomyxoma peritonei (PP),\u0000which has very poor prognosis.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":" 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141130176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: The anterior cruciate ligament (ACL) is a critical structure within the knee joint, playing a pivotal role in maintaining stability during various dynamic movements, including cutting, pivoting, and jumping. This study aims to evaluate the predictive value of pre-operative static ATT in knees with ACL injury. Material and Methods: This study constituted a retrospective descriptive research endeavour encompassing patients who underwent both MRI and knee arthroscopy at Jaipur National University, Institute for Medical Science and Research Centre from October 2023 to March 2024. Clinical data gleaned from in-patient records from the Department of Orthopaedics included demographic particulars such as age, sex, height, weight, and occupation. Patients were dichotomized into two subgroups predicated on arthroscopic ndings: partial ACL tear or complete ACL tear. Subsequently, patient diagnostic images were reviewed, and anterior tibial translation distances were meticulously measured. The means of anterior tibial translation distances in each subgroup were then computed, and the unpaired t-test for the mean difference of each subgroup was executed. Furthermore, a comparative analysis was conducted between the cut-off value derived in this investigation and those reported in antecedent studies. MRI protocols entailed knee protocol scans with the 1.5-Tesla Siemens Sempra, encompassing sagittal, coronal, and axial planes with distinct pulse sequences. Anterior tibial translation distance was meticulously dened as the distance between the most posterior cortex of the tibia and femur, acquired at the midsagittal plane of the lateral femoral condyle. The measurement was conducted relative to a plane parallel to the long axis of the image. Results: The results suggest that the test demonstrates outstanding sensitivity, specicity, positive predictive value, and negative predictive value, all reaching 100% (with condence intervals ranging from 84.56% to 100% for sensitivity and positive predictive value, and from 75.29% to 100% for specicity and negative predictive value). Conclusion: Employing a 7mm threshold on the anterior tibial translation sign for the diagnosis of complete ACL tears represents a valuable clinical tool with signicant implications for patient management.
前十字韧带前交叉韧带（ACL）是膝关节内的重要结构，在切削、旋转和跳跃等各种动态运动中保持稳定性方面发挥着关键作用。本研究旨在评估前交叉韧带损伤膝关节术前静态 ATT 的预测价值。材料与方法：本研究是一项回顾性描述性研究，涵盖 2023 年 10 月至 2024 年 3 月期间在斋浦尔国立大学医学科学研究所和研究中心接受核磁共振成像和膝关节镜检查的患者。从骨科住院病历中收集的临床数据包括年龄、性别、身高、体重和职业等人口统计学特征。根据关节镜，患者被分为两个亚组：前交叉韧带部分撕裂或前交叉韧带完全撕裂。随后，对患者的诊断图像进行审查，并对胫骨前平移距离进行精确测量。然后计算每个亚组胫骨前平移距离的平均值，并对每个亚组的主题差异进行非配对 t 检验。此外，还对本研究得出的临界值与前人研究报告中的临界值进行了比较分析。核磁共振成像方案包括使用1.5特斯拉西门子Sempra扫描膝关节，扫描范围包括矢状面、冠状面和轴面，并使用不同的脉冲序列。胫骨前方平移距离是在股骨外侧髁的矢状面采集到的胫骨和股骨最后方皮质之间的距离，并进行了细致的测量。测量是相对于平行于图像长轴的平面进行的。结果：结果表明，该测试的灵敏度、特city、阳性预测值和阴性预测值均达到了100%（灵敏度和阳性预测值的确信dence intervals从84.56%到100%不等，特city和阴性预测值的确信dence intervals从75.29%到100%不等）。结论：采用胫骨前平移征7毫米阈值诊断前交叉韧带完全撕裂是一种有价值的临床工具，对患者管理具有重要。
{"title":"UTILIZING ANTERIOR TIBIAL TRANSLATION SIGN ON MAGNETIC RESONANCE IMAGING FOR DIFFERENTIAL DIAGNOSIS OF PARTIAL AND COMPLETE ANTERIOR CRUCIATE LIGAMENT TEARS","authors":"Apoorva Tripathi, Ayushi Mittal, Rajeev Mudkavi, Naju Tanya Mudkavi","doi":"10.36106/ijsr/1408684","DOIUrl":"https://doi.org/10.36106/ijsr/1408684","url":null,"abstract":"Introduction: The anterior cruciate ligament (ACL) is a critical structure within the knee joint, playing a pivotal role in maintaining stability\u0000during various dynamic movements, including cutting, pivoting, and jumping. This study aims to evaluate the predictive value of pre-operative\u0000static ATT in knees with ACL injury. Material and Methods: This study constituted a retrospective descriptive research endeavour encompassing\u0000patients who underwent both MRI and knee arthroscopy at Jaipur National University, Institute for Medical Science and Research Centre from\u0000October 2023 to March 2024. Clinical data gleaned from in-patient records from the Department of Orthopaedics included demographic\u0000particulars such as age, sex, height, weight, and occupation. Patients were dichotomized into two subgroups predicated on arthroscopic ndings:\u0000partial ACL tear or complete ACL tear. Subsequently, patient diagnostic images were reviewed, and anterior tibial translation distances were\u0000meticulously measured. The means of anterior tibial translation distances in each subgroup were then computed, and the unpaired t-test for the\u0000mean difference of each subgroup was executed. Furthermore, a comparative analysis was conducted between the cut-off value derived in this\u0000investigation and those reported in antecedent studies. MRI protocols entailed knee protocol scans with the 1.5-Tesla Siemens Sempra,\u0000encompassing sagittal, coronal, and axial planes with distinct pulse sequences. Anterior tibial translation distance was meticulously dened as the\u0000distance between the most posterior cortex of the tibia and femur, acquired at the midsagittal plane of the lateral femoral condyle. The measurement\u0000was conducted relative to a plane parallel to the long axis of the image. Results: The results suggest that the test demonstrates outstanding\u0000sensitivity, specicity, positive predictive value, and negative predictive value, all reaching 100% (with condence intervals ranging from 84.56%\u0000to 100% for sensitivity and positive predictive value, and from 75.29% to 100% for specicity and negative predictive value). Conclusion:\u0000Employing a 7mm threshold on the anterior tibial translation sign for the diagnosis of complete ACL tears represents a valuable clinical tool with\u0000signicant implications for patient management.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":" 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141132845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: COPD is one of the major causes of chronic morbidity and mortality worldwide. It is the fourth leading cause of death in the world(1). Chronic airow limitation of COPD is caused by a mixture of small airway disease (obstructive bronchiolitis) and parenchymal destruction (emphysema), the relative contributions of which vary from person to person. Aim and Objective of the study: To Study the changes of Arterial blood gases in COPD phenotypes. Methods: This Descriptive study was carried out on the patients with chronic obstructive pulmonary disease who were admitted to Victoria hospital, Bangalore from AUGUST 2021 to OCTOBER 2021. Arterial blood gas analysis was used as a diagnostic test in 110 cases of Chronic Obstructive Pulmonary Disease. Interpretation and Conclusion: ABG sampling constitutes a more precise measure of successful gas exchange, oxygenation and happens to be only reliable determination of ventilation success as reected by CO2 content . It also provides valuable information on the acid base balance at a specic point in the course of a patient's illness and plays an important role in the management of Chronic Obstructive Pulmonary Disease. Patients regularly treated in phases of Remission and Exacerbations of COPD the course of illness is slower. Decrease of pH and PaO2 and increase of PaCO2 is statistically signicantly smaller in those received regular treatment in phases of remissions. ABG analysis is indicated in acute exacerbations, during assisted ventilation and to decide prognosis. It should become an integral part of patient management.
{"title":"A DESCRIPTIVE STUDY OF ARTERIAL BLOOD GAS PATTERNS IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE","authors":"Mohan J, Basavaraju T J, Darshan G R, S. B. L.","doi":"10.36106/ijsr/7508548","DOIUrl":"https://doi.org/10.36106/ijsr/7508548","url":null,"abstract":"Background: COPD is one of the major causes of chronic morbidity and mortality worldwide. It is the fourth leading cause of death in the\u0000world(1). Chronic airow limitation of COPD is caused by a mixture of small airway disease (obstructive bronchiolitis) and parenchymal\u0000destruction (emphysema), the relative contributions of which vary from person to person. Aim and Objective of the study: To Study the changes\u0000of Arterial blood gases in COPD phenotypes. Methods: This Descriptive study was carried out on the patients with chronic obstructive pulmonary\u0000disease who were admitted to Victoria hospital, Bangalore from AUGUST 2021 to OCTOBER 2021. Arterial blood gas analysis was used as a\u0000diagnostic test in 110 cases of Chronic Obstructive Pulmonary Disease. Interpretation and Conclusion: ABG sampling constitutes a more\u0000precise measure of successful gas exchange, oxygenation and happens to be only reliable determination of ventilation success as reected by CO2\u0000content . It also provides valuable information on the acid base balance at a specic point in the course of a patient's illness and plays an important\u0000role in the management of Chronic Obstructive Pulmonary Disease. Patients regularly treated in phases of Remission and Exacerbations of COPD\u0000the course of illness is slower. Decrease of pH and PaO2 and increase of PaCO2 is statistically signicantly smaller in those received regular\u0000treatment in phases of remissions. ABG analysis is indicated in acute exacerbations, during assisted ventilation and to decide prognosis. It should\u0000become an integral part of patient management.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"30 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141137358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Methods: Epidermal inclusion cysts are the most common cutaneous cysts, but malignant transformation in them is extremely rare. We present a case of a 63-year-old female with a swelling in the right gluteal region with associated discharge that was resected based on the clinical impression and cytology of an epidermal inclusion cyst. Histopathologic exam showed atypical cells with enlarged nuclei and prominent nucleoli with brisk mitotic activity, and on IHC, these cells were positive for PanCK and P40 and negative for Sox10, conrming the diagnosis of Poorly Differentiated Squamous Cell Carcinoma. There are 56 reported cases of SCC arising on a background Conclusion: of epidermal inclusion cysts in literature. Although epidermal inclusion cysts are usually benign, excision is recommended for atypical cysts with high suspicion for malignancy. They should be excised intact and should undergo histopathological examination to rule out incipient malignancy.
{"title":"SQUAMOUS CELL CARCINOMA ARISING ON A BACKGROUND OF EPIDERMAL INCLUSION CYST OVER THE GLUTEAL REGION – A CASE REPORT","authors":"Praharsha G S, Patil Virupaxagouda, Kailas C T","doi":"10.36106/ijsr/8109036","DOIUrl":"https://doi.org/10.36106/ijsr/8109036","url":null,"abstract":"Background: Methods: Epidermal inclusion cysts are the most common cutaneous cysts, but malignant transformation in them is extremely rare.\u0000We present a case of a 63-year-old female with a swelling in the right gluteal region with associated discharge that was resected based on the clinical\u0000impression and cytology of an epidermal inclusion cyst. Histopathologic exam showed atypical cells with enlarged nuclei and prominent nucleoli\u0000with brisk mitotic activity, and on IHC, these cells were positive for PanCK and P40 and negative for Sox10, conrming the diagnosis of Poorly\u0000Differentiated Squamous Cell Carcinoma. There are 56 reported cases of SCC arising on a background Conclusion: of epidermal inclusion cysts in\u0000literature. Although epidermal inclusion cysts are usually benign, excision is recommended for atypical cysts with high suspicion for malignancy.\u0000They should be excised intact and should undergo histopathological examination to rule out incipient malignancy.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"21 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141141378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Postoperative sore throat (POST) is a common undesirable outcome of tracheal intubation, with prevalence ranging from 21% to 65%. This is inuenced by factors such as mechanical trauma during intubation, tracheal tube cuff pressure causing mucosal erosion, inammation, and dehydration [1,2]. Prolonged intubation can lead to serious consequences, while even a short tracheal intubation period of one hour can cause extensive damage to the tracheal and laryngeal epithelium. Although POST is usually a self-limiting condition that resolves within 12-24 hours, its prevention is important to reduce [3] hospital stay and improve patient satisfaction.
术后咽喉痛（POST）是气管插管后常见的不良后果，发生率从 21% 到 65% 不等。插管过程中的机械性创伤、气管导管袖带压力导致的粘膜侵蚀、ammation 和脱水等因素都会影响POST的发生[1,2]。长时间插管可导致严重后果，而即使短短的一小时气管插管也会对气管和喉上皮造成广泛损伤。虽然 POST 通常是一种自限性病症，可在 12-24 小时内缓解，但预防 POST 对减少[3] 住院时间和提高患者满意度非常重要。
{"title":"COMPARISON OF NEBULIZED KETAMINE VERSUS NEBULIZED MAGNESIUM SULFATE FOR PREVENTION OF POST OPERATIVE SORE THROAT IN PATIENTS UNDERGOING GENERALANESTHESIA REQUIRING ENDOTRACHEAL INTUBATION: A DOUBLE BLIND RANDOMIZED CONTROL TRIAL","authors":"Jayesh Shakeet, Sandhya Lata, Ankit Kumar","doi":"10.36106/ijsr/4307654","DOIUrl":"https://doi.org/10.36106/ijsr/4307654","url":null,"abstract":"Postoperative sore throat (POST) is a common undesirable outcome of\u0000tracheal intubation, with prevalence ranging from 21% to 65%. This is\u0000inuenced by factors such as mechanical trauma during intubation,\u0000tracheal tube cuff pressure causing mucosal erosion, inammation,\u0000and dehydration [1,2]. Prolonged intubation can lead to serious\u0000consequences, while even a short tracheal intubation period of one\u0000hour can cause extensive damage to the tracheal and laryngeal\u0000epithelium. Although POST is usually a self-limiting condition that\u0000resolves within 12-24 hours, its prevention is important to reduce\u0000[3] hospital stay and improve patient satisfaction.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":"45 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141141007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sneha Jethwani, Amit Benjamin, Sangeeta Muglikar, K. Nalawade, Aishwarya Kotkar
Objective: The objective of this systematic review is to compare and clinically evaluate the adjunctive benets of a diode laser (DL) to conventional open ap debridement (OFD) in the treatment of chronic periodontitis. DL is an excelle Background: nt soft tissue surgical laser, indicated for soft tissue curettage or sulcular debridement with an additional bactericidal effect. Studies have been conducted to determine the effect of DL as an adjunct to OFD. There is limited documentation regarding the clinical effectiveness to prove adjunctive effect of OFD in the surgical periodontal therapy. Only randomized controlled trials (RCTs) assessing use of DL only in Methods: continuous and contact mode on undersurface of ap post-conventional OFD for treatment of chronic periodontitis in the test group were considered. Studies published only in English language with follow-up periods of 3 and 6 months post-operatively and assessing probing pocket depth (PPD) and clinical attatchment level (CAL) as the outcomes were considered. A total of 6 RCTs were included in this systematic review. Cochrane Risk of Bias tool was used for assessing the risk of bias. 3/6 studies concluded that DL signicantly led to reduction in PPD or ga Results: in in CAL when used as adjunct to OFD. Whereas, other 3/6 studies concluded that DL did not signicantly lead to reduction in PPD or gain in CAL when used as adjunct to OFD. Conclusion: DL can be used as an adjunct to standard treatments (OFD) of chronic periodontitis i.e; chronic periodontitis rather than as a replacement for standard treatments.
{"title":"CLINICAL EVALUATION OF EFFECTIVENESS OF DIODE LASER AS AN ADJUNCT TO OPENFLAP DEBRIDEMENT AS COMPARED TO OPEN FLAP DEBRIDEMENT ALONE IN THE PERIODONTAL TREATMENT OUTCOME OF PATIENTS WITH CHRONIC PERIODONTITIS – A SYSTEMATIC REVIEW","authors":"Sneha Jethwani, Amit Benjamin, Sangeeta Muglikar, K. Nalawade, Aishwarya Kotkar","doi":"10.36106/ijsr/7107425","DOIUrl":"https://doi.org/10.36106/ijsr/7107425","url":null,"abstract":"Objective: The objective of this systematic review is to compare and clinically evaluate the adjunctive benets of a diode laser (DL) to\u0000conventional open ap debridement (OFD) in the treatment of chronic periodontitis. DL is an excelle Background: nt soft tissue surgical laser,\u0000indicated for soft tissue curettage or sulcular debridement with an additional bactericidal effect. Studies have been conducted to determine the\u0000effect of DL as an adjunct to OFD. There is limited documentation regarding the clinical effectiveness to prove adjunctive effect of OFD in the\u0000surgical periodontal therapy. Only randomized controlled trials (RCTs) assessing use of DL only in Methods: continuous and contact mode on\u0000undersurface of ap post-conventional OFD for treatment of chronic periodontitis in the test group were considered. Studies published only in\u0000English language with follow-up periods of 3 and 6 months post-operatively and assessing probing pocket depth (PPD) and clinical attatchment\u0000level (CAL) as the outcomes were considered. A total of 6 RCTs were included in this systematic review. Cochrane Risk of Bias tool was used for\u0000assessing the risk of bias. 3/6 studies concluded that DL signicantly led to reduction in PPD or ga Results: in in CAL when used as adjunct to OFD.\u0000Whereas, other 3/6 studies concluded that DL did not signicantly lead to reduction in PPD or gain in CAL when used as adjunct to OFD.\u0000Conclusion: DL can be used as an adjunct to standard treatments (OFD) of chronic periodontitis i.e; chronic periodontitis rather than as a\u0000replacement for standard treatments.","PeriodicalId":14358,"journal":{"name":"International journal of scientific research","volume":" 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141132885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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