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Progressive analysis of language and sensory profile skills in children with auditory brainstem implants and cochlear implants 植入听觉脑干和人工耳蜗儿童语言和感觉技能的进展分析
IF 1.3 4区 医学 Q3 OTORHINOLARYNGOLOGY
International journal of pediatric otorhinolaryngology
Pub Date : 2026-01-28 DOI: 10.1016/j.ijporl.2026.112747
Nuriye Yildirim Gökay , Banu Baş , Beyza Demi̇rtaş Yilmaz , Esra Yücel

Purpose

This study aimed to analyze and compare the sensory profiles and language skills of children with auditory brainstem implants (ABI) and cochlear implants (CI) over one year.

Method

This prospective comparative study included 24 children aged 6–8 years and 11 months, consisting of 12 bimodal CI-ABI users and 12 bilateral CI users. All children received scheduled auditory rehabilitation and audiological follow-ups. Sensory profiles were assessed using the Sensory Profile scale, while school-age language skills were evaluated using the Test of Language Development-Primary: Fourth Edition. The language and sensory profile scores of the children from one year prior and later to the study were compared. Additionally, the progress levels of the groups within one year were compared.

Results

Both children with CI and ABI demonstrated significant improvements in verbal language skills (e.g., sentence repetition, p < 0.001), registration, sensory seeking, sensory input processing, low endurance, and fine motor skills over the year. However, children with CI showed significantly greater progress in verbal language composite scores (p = 0.015) and subskills such as registration and fine motor skills (p < 0.05) compared to the ABI group. Multivariate analysis further revealed that hearing loss etiology and implantation mode were significant factors influencing developmental outcomes.

Conclusion

Hearing implants not only enhance language skills but also facilitate progress in children's sensory profile sub-skills. A holistic approach that evaluates hearing, language, and overall development is recommended for hearing-impaired children.
目的分析和比较听性脑干植入（ABI）和人工耳蜗植入（CI）儿童1年内的感觉特征和语言技能。方法本前瞻性比较研究纳入24例6-8岁11个月的儿童，其中12例双侧CI- abi使用者和12例双侧CI使用者。所有儿童均接受预定的听力康复和听力学随访。感官档案使用感官档案量表进行评估，而学龄语言技能使用语言发展测试-小学：第四版进行评估。研究人员比较了研究前后一年儿童的语言和感官评分。此外，比较两组在一年内的进展水平。结果CI和ABI患儿在言语语言技能（如句子重复，p < 0.001）、注册、感觉寻找、感觉输入处理、低耐力和精细运动技能方面均有显著改善。然而，与ABI组相比，CI组儿童在口头语言综合得分（p = 0.015）和子技能（如注册和精细运动技能）方面的进步明显更大（p < 0.05）。多因素分析进一步显示，听力损失的病因和植入方式是影响发育结局的重要因素。结论植入助听器不仅能提高儿童的语言能力，还能促进儿童感觉轮廓亚技能的进步。一个全面的方法，评估听力，语言，和整体发展建议听障儿童。
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引用次数: 0
Analyses of GJB2 status in hereditary and non-syndromic hearing loss cases in Turkey reveal pathogenicity of rare c.247_249delTTC variant 对土耳其遗传性和非综合征性听力损失病例GJB2状态的分析揭示了罕见的c.247_249delTTC变异的致病性
IF 1.3 4区 医学 Q3 OTORHINOLARYNGOLOGY
International journal of pediatric otorhinolaryngology
Pub Date : 2026-01-26 DOI: 10.1016/j.ijporl.2026.112739
Sait Tümer , Mustafa Bülent Şerbetçioğlu , Günay Kırkım , Seda Nur Homurlu , Oğuz Altungöz
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引用次数: 0
Composite chondroperichondrial clip (“Triple-C”) tympanoplasty in pediatric patients 复合软骨软骨膜夹（“3c”）鼓室成形术在儿科患者中的应用。
IF 1.3 4区 医学 Q3 OTORHINOLARYNGOLOGY
International journal of pediatric otorhinolaryngology
Pub Date : 2026-01-25 DOI: 10.1016/j.ijporl.2026.112746
Shadi Shinnawi , Roni Barzilai , Majd Khoury , Muhammad Zahlaka , Ali Hammad , Mauricio Cohen-Vaizer
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引用次数: 0
The role of nasopharyngeal airways in Robin sequence: Insights from a retrospective cohort study with review of the literature 鼻咽气道在罗宾序列中的作用：来自回顾性队列研究的见解，并回顾了文献
IF 1.3 4区 医学 Q3 OTORHINOLARYNGOLOGY
International journal of pediatric otorhinolaryngology
Pub Date : 2026-01-24 DOI: 10.1016/j.ijporl.2026.112744
Shirley van de Velde , Maartje Haasnoot , Saskia Coenraad , J. Peter W. Don Griot , Aebele B. Mink van der Molen , Emma C. Paes
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引用次数: 0
Tracheal cartilaginous sleeve prevalence in syndromic craniosynostosis: A single institution study 气管软骨套筒在综合征性颅缝闭塞中的患病率：一项单机构研究。
IF 1.3 4区 医学 Q3 OTORHINOLARYNGOLOGY
International journal of pediatric otorhinolaryngology
Pub Date : 2026-01-24 DOI: 10.1016/j.ijporl.2026.112745
Roy K. Park , Katherine Hu , Zoe H. Fullerton , Melissa C. Lee , Rohit K. Khosla , Karthik Balakrishnan

Purpose

This study aimed to evaluate the incidence of tracheal cartilaginous sleeve (TCS) among syndromic craniosynostosis patients, as well as describe their genetic profiles, associated co-morbidities, and operative outcomes.

Methods

We performed a retrospective analysis of syndromic craniosynostosis patients (Apert, Crouzon, and Pfeiffer) at a single tertiary academic center between January 1, 2002, and February 1, 2024.

Results

39 patients with syndromic craniosynostosis were identified, with 17 patients (17/39, 43.6%) undergoing airway evaluation. 1 patient (1/17, 5.9%) was diagnosed with TCS, but 5 patients (5/17, 29.4%) had other airway abnormalities, all reflecting abnormalities of the airway wall or some type of airway stenosis. 28 patients (28/39, 73.7%) presented with a diagnosis of OSA, and 7 patients (7/39, 17.9%) of patients presented with choanal anomaly (atresia or stenosis). 32 patients (32/39, 82.1%) had genetic sequencing information available, with the most common mutations affecting p.P253R within the FGFR2 gene in 7 patients. No patients in our cohort presented with a p.W290 mutation and 7 patients presented with a p.C342 mutation, of which 4 patients had the p.C342Y mutation.

Conclusion

The true prevalence of TCS may be likely lower than prior reports, which may aid with alleviating some familial anxiety and provide additional context and data for medical counseling and decision-making. Nonetheless, all patients should be strongly recommended to undergo airway evaluation given the risks associated with TCS, the high prevalence of structural airway anomalies, and the overall low risk of airway evaluation.
目的：本研究旨在评估气管软骨套（TCS）在综合征性颅缝闭塞患者中的发病率，并描述其遗传谱、相关合并症和手术结果。方法：回顾性分析2002年1月1日至2024年2月1日在一个三级学术中心的综合征性颅缝闭锁患者（Apert， Crouzon和Pfeiffer）。结果：39例综合征性颅缝闭锁患者中，17例（17/39,43.6%）接受气道评估。1例（1/17,5.9%）患者被诊断为TCS， 5例（5/17,29.4%）患者有其他气道异常，均反映气道壁异常或某种类型的气道狭窄。28例（28/39,73.7%）患者诊断为OSA， 7例（7/39,17.9%）患者表现为后鼻孔异常（闭锁或狭窄）。32例患者（32/39,82.1%）有基因测序信息，其中最常见的突变影响7例FGFR2基因内的p.P253R。我们的队列中没有患者出现p.W290突变，7例患者出现p.C342突变，其中4例患者出现p.C342Y突变。结论：TCS的真实患病率可能低于之前的报道，这可能有助于减轻一些家庭焦虑，并为医疗咨询和决策提供额外的背景和数据。尽管如此，考虑到TCS的相关风险、结构性气道异常的高患病率以及气道评估的总体低风险，强烈建议所有患者接受气道评估。
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引用次数: 0
Demography and outcomes of frozen tongue: a scoping review of Scandinavian tundra tongue cases 人口统计学和冰冻舌的结果：斯堪的纳维亚苔原舌病例的范围审查。
IF 1.3 4区 医学 Q3 OTORHINOLARYNGOLOGY
International journal of pediatric otorhinolaryngology
Pub Date : 2026-01-20 DOI: 10.1016/j.ijporl.2026.112740
Anders Hagen Jarmund , Sofie Eline Tollefsen , Baard Cristoffer Sakshaug , Yashar Honarmandi , Sverre Helge Torp

Background

Children occasionally adhere their tongues to cold metal surfaces during winter (“tundra tongue”), but little is known about the epidemiology and outcomes of these cases.

Objectives

To explore the following questions: who experiences tundra tongue, under which circumstances does it occur, and what are the outcomes?

Methods

We conducted a scoping review to identify case reports published in historical newspapers from Norway, Sweden and Denmark using national library databases. Epidemiological data were charted manually from newspaper items describing literal frozen tongues.

Results

Among 17,009 unique search hits, 856 reports of 113 different cases were identified. Almost all cases (96 %) involved children, median age 5.25 years, and the majority were boys (63 %). Tongues were most often frozen to railings (40 %). Ambient temperature was reported in 18 cases with a median of −16.5 °C. Outcomes ranged from discomfort to potential amputation of tongue tissue, with 20 (18 %) cases involving a doctor or a hospital. Severe injuries were reported in several cases through three distinct mechanisms: (1) the direct effect of cold on tissue, (2) detachment injuries, and (3) the consequences of immobility.

Conclusion

Children, and especially boys, in wintertime, are vulnerable to tundra tongue. Most cases had no or mild consequences but severe injuries were also described in multiple cases. Hence, parents, health care professionals and policymakers should not underestimate the potential harm of tundra tongue.
背景：儿童在冬季偶尔会将舌头粘在寒冷的金属表面（“苔原舌头”），但对这些病例的流行病学和结果知之甚少。目的：探讨以下问题：谁会经历冻土带舌头，在什么情况下会发生，结果是什么？方法：我们使用国家图书馆数据库对挪威、瑞典和丹麦的历史报纸上发表的病例报告进行了范围综述。流行病学数据是根据报纸上描述冰冻舌头的文字手工绘制的。结果：在17,009个独立搜索命中，确定了113个不同病例的856个报告。几乎所有病例（96%）涉及儿童，中位年龄5.25岁，大多数为男孩（63%）。舌头最常冻僵在栏杆上（40%）。18例报告环境温度中位数为-16.5°C。结果从不适到可能的舌组织截肢不等，其中20例（18%）涉及医生或医院。据报道，在一些病例中，严重的损伤有三种不同的机制：(1)冷对组织的直接影响，(2)脱离损伤，(3)不活动的后果。结论：冬季儿童，尤其是男孩易患冻土带舌病。大多数情况下没有或轻微的后果，但严重的伤害也在多个情况下描述。因此，家长、卫生保健专业人员和决策者不应低估冻土带舌头的潜在危害。
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引用次数: 0
Exploring cochlear implantation and quality of life in pediatric recipients with autism spectrum disorder 探讨人工耳蜗植入对儿童自闭症谱系障碍患者生活质量的影响
IF 1.3 4区 医学 Q3 OTORHINOLARYNGOLOGY
International journal of pediatric otorhinolaryngology
Pub Date : 2026-01-20 DOI: 10.1016/j.ijporl.2026.112725
Meredith Allen , Camille Reeves , Sofia Torres-Small , Robert J. Yawn , Charles B. Macdonald , Samuel H. Smith , Celine Richard

Objective

This study aims to comprehensively assess the timing and accessibility of cochlear implantation, patterns of its utilization, and the associated outcomes related to quality of life (QoL), in children diagnosed with autism spectrum disorder (ASD).

Study design

Retrospective case-control review, and cross-sectional hearing-related QoL survey.

Setting

Tertiary children's hospital.

Methods

This investigation employed a retrospective case-control design, complemented by a cross-sectional hearing-related QoL survey using the HEAR-QL questionnaires. Outcomes were compared between two populations of pediatric cochlear implant recipients: one group with a preoperative diagnosis of ASD and a control group of neurotypical peers. A review of 413 patient records from 2000 to 2022 identified 22 eligible patients with ASD and matched controls. Of these, 16 participants from the ASD group and 16 controls completed the prospective quality-of-life surveys.

Results

The time between the definitive diagnosis of profound sensorineural hearing loss and the cochlear implantation evaluation was longer for patients with ASD. However, no other significant differences in care delays were observed between ASD children and controls, including time to CI qualification, and implantation. Nevertheless, children with ASD aged 2–6 years showed poorer outcomes in social interaction (p = 0.02) and new social situations (p = 0.02 and 0.04). Despite these behavioral differences, no significant disparity in hearing-related QoL-related communication outcomes was observed.

Conclusion

The study shows that cochlear implant benefit children with ASD, with expected challenges not affecting overall success. It underscores the importance of individualized approaches to address delays in CI evaluation, communication, and social interaction challenges. These insights can help guide care teams, parents and educators in setting realistic expectations following cochlear implantation.
目的综合评价自闭症谱系障碍（ASD）儿童人工耳蜗植入的时机、可及性、使用模式以及与生活质量（QoL）相关的结果。研究设计：回顾性病例对照研究和听力相关生活质量横断面调查。设置三级儿童医院。方法本研究采用回顾性病例对照设计，并辅以使用听力- ql问卷进行听力相关生活质量横断面调查。比较两组儿童人工耳蜗受者的结果：一组术前诊断为ASD，对照组为神经正常的同龄人。对2000年至2022年413例患者记录的回顾确定了22例符合条件的ASD患者和匹配的对照组。其中，来自ASD组的16名参与者和对照组的16名参与者完成了预期生活质量调查。结果ASD患者从明确诊断为重度感音神经性听力损失到人工耳蜗植入评估的时间较长。然而，在ASD儿童和对照组之间，在护理延迟方面没有观察到其他显著差异，包括CI认证时间和植入时间。然而，2-6岁ASD儿童在社交互动（p = 0.02）和新社会情境（p = 0.02和0.04）方面表现较差。尽管存在这些行为差异，但在听力相关的生活质量相关的沟通结果中没有观察到显著差异。结论：研究表明人工耳蜗对ASD儿童有益，预期的挑战不会影响整体的成功。它强调了个性化方法在解决CI评估、沟通和社会互动挑战中的延迟的重要性。这些见解可以帮助指导护理团队、家长和教育工作者在人工耳蜗植入后设定切合实际的期望。
{"title":"Exploring cochlear implantation and quality of life in pediatric recipients with autism spectrum disorder","authors":"Meredith Allen ,&nbsp;Camille Reeves ,&nbsp;Sofia Torres-Small ,&nbsp;Robert J. Yawn ,&nbsp;Charles B. Macdonald ,&nbsp;Samuel H. Smith ,&nbsp;Celine Richard","doi":"10.1016/j.ijporl.2026.112725","DOIUrl":"10.1016/j.ijporl.2026.112725","url":null,"abstract":"<div><h3>Objective</h3><div>This study aims to comprehensively assess the timing and accessibility of cochlear implantation, patterns of its utilization, and the associated outcomes related to quality of life (QoL), in children diagnosed with autism spectrum disorder (ASD).</div></div><div><h3>Study design</h3><div>Retrospective case-control review, and cross-sectional hearing-related QoL survey.</div></div><div><h3>Setting</h3><div>Tertiary children's hospital.</div></div><div><h3>Methods</h3><div>This investigation employed a retrospective case-control design, complemented by a cross-sectional hearing-related QoL survey using the HEAR-QL questionnaires. Outcomes were compared between two populations of pediatric cochlear implant recipients: one group with a preoperative diagnosis of ASD and a control group of neurotypical peers. A review of 413 patient records from 2000 to 2022 identified 22 eligible patients with ASD and matched controls. Of these, 16 participants from the ASD group and 16 controls completed the prospective quality-of-life surveys.</div></div><div><h3>Results</h3><div>The time between the definitive diagnosis of profound sensorineural hearing loss and the cochlear implantation evaluation was longer for patients with ASD. However, no other significant differences in care delays were observed between ASD children and controls, including time to CI qualification, and implantation. Nevertheless, children with ASD aged 2–6 years showed poorer outcomes in social interaction (p = 0.02) and new social situations (p = 0.02 and 0.04). Despite these behavioral differences, no significant disparity in hearing-related QoL-related communication outcomes was observed.</div></div><div><h3>Conclusion</h3><div>The study shows that cochlear implant benefit children with ASD, with expected challenges not affecting overall success. It underscores the importance of individualized approaches to address delays in CI evaluation, communication, and social interaction challenges. These insights can help guide care teams, parents and educators in setting realistic expectations following cochlear implantation.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"202 ","pages":"Article 112725"},"PeriodicalIF":1.3,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146024595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding racial and ethnic disparities in perioperative pain management following routine ambulatory surgery center pediatric tonsillectomy 了解常规门诊手术中心儿童扁桃体切除术后围手术期疼痛管理的种族差异
IF 1.3 4区 医学 Q3 OTORHINOLARYNGOLOGY
International journal of pediatric otorhinolaryngology
Pub Date : 2026-01-17 DOI: 10.1016/j.ijporl.2026.112738
Francesca T. deFaria , Pilar Preciado , Alisha R. Pershad , Rashel Moscoso-Morales , Giuliana Di Bono , Alexa Shahine , Aryana Kavuri , Timothy Wills , Hengameh K. Behzadpour , Sophie Pestieau , Diego A. Preciado , Caroll Vazquez-Colon
{"title":"Understanding racial and ethnic disparities in perioperative pain management following routine ambulatory surgery center pediatric tonsillectomy","authors":"Francesca T. deFaria ,&nbsp;Pilar Preciado ,&nbsp;Alisha R. Pershad ,&nbsp;Rashel Moscoso-Morales ,&nbsp;Giuliana Di Bono ,&nbsp;Alexa Shahine ,&nbsp;Aryana Kavuri ,&nbsp;Timothy Wills ,&nbsp;Hengameh K. Behzadpour ,&nbsp;Sophie Pestieau ,&nbsp;Diego A. Preciado ,&nbsp;Caroll Vazquez-Colon","doi":"10.1016/j.ijporl.2026.112738","DOIUrl":"10.1016/j.ijporl.2026.112738","url":null,"abstract":"","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"202 ","pages":"Article 112738"},"PeriodicalIF":1.3,"publicationDate":"2026-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146075219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetic screening for hearing impairment and the genotype-phenotype correlation of GJB2 c.109G>A variants in 47,729 neonates: a population-based study in southern China 47,729名新生儿GJB2 c.109G>A基因型-表型相关性的听力障碍遗传筛查：一项基于华南人群的研究
IF 1.3 4区 医学 Q3 OTORHINOLARYNGOLOGY
International journal of pediatric otorhinolaryngology
Pub Date : 2026-01-17 DOI: 10.1016/j.ijporl.2026.112737
Jianjun Li, Meng Guo, Wenwen Yu, Li Ma, Qi Zhang, Qi Wang, Xueyu Yang, Hongyun He, Wenlan Liu

Background

This study aimed to characterize the Variant profile of the 4 common deafness-causing genes and evaluated the genotype-phenotype correlation of GJB2 c.109G > A variants in a neonatal cohort, providing insights for early diagnosis of congenital hearing loss.

Methods

A total of 47,729 newborns in Shenzhen underwent integrated deafness gene screening (23 common pathogenic variants across GJB2, SLC26A4, MT-RNR1, and GJB3) and two-stage audiometric assessments from January 2022 to November 2024. Participants were stratified into three groups based on GJB2 c.109G > A genotypes: homozygous (Group A, n = 487), compound heterozygous (Group B, n = 87), and heterozygous carriers (Group C, n = 8055). Hearing function was evaluated via otoacoustic emissions (OAE) at 48 h postpartum, with non-passing cases receiving follow-up OAE and auditory brainstem response (ABR) testing at 42 days.

Results

Deafness-associated Variant were detected in 21.56 % (10,291/47,729) of neonates, with GJB2 exhibiting the highest carrier frequency (20.25 %), followed by SLC26A4 (1.44 %), MT-RNR1 (0.28 %), and GJB3 (0.18 %). The GJB2 c.109G > A locus dominated the variant landscape, with a carrier rate of 18.12 % (n = 8649) and an minor allele frequency of 9.57 %. The overall pass rates for the two-stage audiological assessments differed significantly across the groups: 63.66 % (Group A), 70.11 % (Group B), and 98.92 % (Group C). Bilateral hearing impairment predominated in Groups A and B.

Conclusion

The GJB2 c.109G > A Variant represents the most prevalent pathogenic variant in Shenzhen neonates, and the infants carrying deafness-causing genotypes of this variant presents relatively high hearing screening pass rate. Integrated genetic and audiometric screening could enhance early identification of high-risk infants.
背景：本研究旨在研究新生儿队列中4种常见致聋基因的变异谱，并评估GJB2 c.109G > A变异的基因型-表型相关性，为先天性听力损失的早期诊断提供依据。方法：从2022年1月至2024年11月，深圳共有47,729名新生儿接受了综合耳聋基因筛查（GJB2、SLC26A4、MT-RNR1和GJB3的23种常见致病变异）和两阶段听力评估。根据GJB2 C . 109g > A基因型将参与者分为三组：纯合子（A组，n = 487）、复合杂合子（B组，n = 87）和杂合子携带者（C组，n = 8055）。在产后48 h通过耳声发射（OAE）评估听力功能，未通过的病例在产后42天接受随访的OAE和听觉脑干反应（ABR）测试。结果：新生儿中耳聋相关变异检出率为21.56%(10,291/47,729)，其中GJB2的检出率最高（20.25%），其次为SLC26A4（1.44%）、MT-RNR1（0.28%）、GJB3（0.18%）。GJB2 c.109G > A基因座在变异格局中占主导地位，携带率为18.12% (n = 8649)，等位基因频率为9.57%。两阶段听力学评估的总体通过率在各组之间差异显著：63.66% （A组），70.11% （B组）和98.92% （C组）。结论：GJB2 c.109G > A变异是深圳新生儿中最常见的致病变异，携带该变异致聋基因型的婴儿听力筛查通过率较高。综合遗传和听力筛查可提高高危婴儿的早期识别。
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引用次数: 0
Clinical trial assessing the use of optical coherence tomography in decision making for children presenting with acute otitis media 临床试验评估光学相干断层扫描在儿童急性中耳炎决策中的应用
IF 1.3 4区 医学 Q3 OTORHINOLARYNGOLOGY
International journal of pediatric otorhinolaryngology
Pub Date : 2026-01-14 DOI: 10.1016/j.ijporl.2026.112728
Joseph E. Kerschner , Roger A. Daley Jr. , Roxanne Link , Rachel M. Jones , Katherine J. Peterson , Robert H. Chun , Valerie A. Flanary , Michael Gorelik , Kristina L. Keppel , Matthew Maksimoski , Marsha Malloy , Timothy J. Martin , Michael E. McCormick , Thomas C. Robey , Sadia Ansari , Grace M. Matoska , Caroline A. Rupcich , Marineta L. Saunderson , Sophie G. Shay , Cecille Sulman , Stephen A. Boppart

Objective

To identify the ability of optical coherence tomography (OCT) to assist in the diagnosis and treatment of patients presenting to a primary care provider with signs and symptoms suggesting acute otitis media (AOM).

Design-Setting-Participants

An NIH-funded clinical trial was conducted and enrolled 75 children between 1 and under 7 years of age. Children presented with complaints of ear pain or suspected ear infection from their caregiver history to primary care clinics associated with an academic children's hospital. These patients upon presentation were eligible to enroll in the trial. Following a complete history and physical exam, including pneumatic otoscopy (PO), patients were provided with a diagnosis and treatment plan. Diagnoses included: AOM, middle ear effusion without AOM, or no evidence of otitis media with a clear middle ear space. Following this, OCT was performed, and the diagnosis and treatment plan was reassessed using this data.

Results

The diagnosis and/or treatment plan changed for 15.3 % of patients following the use of OCT compared with the initial use of PO. The greatest influence was seen in the patient group with MEE without AOM, with 36 % (5/14) of these patients having their diagnosis and/or treatment plan changed after OCT was employed.

Conclusions

OCT provides an additional adjunct for primary care providers to enhance visualization of the tympanic membrane and middle ear space. This data, in our clinical trial, resulted in enhanced clinical decision making, in particular for patients with MEE who were not diagnosed with AOM on PO.

Trial registration information

Coherent Optical Detection of Middle Ear Disease (OCTII). Clinicaltrials.gov ID number: NCT05353569.
目的确定光学相干断层扫描（OCT）在初级保健提供者诊断和治疗体征和症状提示急性中耳炎（AOM）患者的能力。设计-设置-参与者一项美国国立卫生研究院资助的临床试验进行了，并招募了75名1至7岁以下的儿童。儿童提出的投诉，耳部疼痛或疑似耳部感染从他们的照顾者的历史，以初级保健诊所与学术儿童医院。这些患者在就诊时就有资格参加试验。经过完整的病史和体检，包括气动耳镜检查（PO），为患者提供诊断和治疗计划。诊断包括：中耳炎、无中耳炎的中耳积液或无中耳炎伴中耳间隙清晰的证据。在此之后，进行OCT检查，并根据这些数据重新评估诊断和治疗方案。结果使用OCT后与首次使用PO相比，15.3%的患者的诊断和/或治疗方案发生了变化。在没有AOM的MEE患者组中影响最大，36%（5/14）的患者在使用OCT后诊断和/或治疗计划发生了变化。结论超声ct为初级保健医生提供了一种增强鼓膜和中耳间隙可视化的辅助手段。在我们的临床试验中，这一数据增强了临床决策，特别是对于那些在PO上未被诊断为AOM的MEE患者。中耳疾病相干光学检测（OCTII）试验注册信息。临床试验。gov ID号：NCT05353569。
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引用次数: 0
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