International journal of pediatric otorhinolaryngology最新文献

英文中文

Ankyloglossia and its association with sleep-disordered breathing in children: A systematic review 儿童强直性失听症及其与睡眠呼吸障碍的关系：一项系统综述

IF 1.3 4区医学 Q3 OTORHINOLARYNGOLOGY

International journal of pediatric otorhinolaryngology

Pub Date : 2026-01-09 DOI: 10.1016/j.ijporl.2026.112717

Trimartani Koento , Shefilyn Widjaja

引用次数: 0

Gender-specific acoustic profile of male children aged 10–15 years: Fundamental frequency and formant changes 10-15岁男性儿童的性别声学特征：基本频率和共振峰的变化

IF 1.3 4区医学 Q3 OTORHINOLARYNGOLOGY

International journal of pediatric otorhinolaryngology

Pub Date : 2026-01-07 DOI: 10.1016/j.ijporl.2026.112709

Raveendran Revathi , M.B. Shivani , H.J. Sanjana , P. Prathiksha

引用次数: 0

Safety and tolerability of a standardized treatment regimen for Mycobacterium abscessus otomastoiditis 脓肿分枝杆菌耳乳突炎标准化治疗方案的安全性和耐受性。

IF 1.3 4区医学 Q3 OTORHINOLARYNGOLOGY

International journal of pediatric otorhinolaryngology

Pub Date : 2026-01-06 DOI: 10.1016/j.ijporl.2026.112715

Theresa Y.S. Leow , Stijn Bekkers , Stefanie S.V. Henriet , Myrthe K.S. Hol , Arno M. Janssen , Thijs T.G. Jansen , Henricus P.M. Kunst , Sjoert A.H. Pegge , Jerome J. Waterval , Jakko van Ingen , Koen J. Van Aerde

Background

This study aims to evaluate the drug-induced adverse events of our institutional multidisciplinary clinical pathway for M. abscessus treatment and gives suggestions for monitoring and management of adverse events.

Methods

Patients treated according to a published institutional clinical pathway in our tertiary referral centre were included. Main outcome measures were the type and frequency of adverse events documented. In addition, reasons for drug cessation or interruption were evaluated.

Results

Ten patients were included (mean age: 8 years old; male: 70 %). All patients suffered from adverse events, in 90 % of the cases leading to pre-term drug interruption (40 %) or even cessation (70 %) of one or more antibiotics. Most common adverse events were gastrointestinal (100 %), weight loss (60 %), elevated liver enzymes (70 %), hypoalbuminemia (90 %) and hypertriglyceridemia (70 %). Most adverse events were likely caused by tigecycline. All children were clinically cured after the treatment and did not suffer from long-term physical adverse events.

Conclusions

The multidrug treatment for M. abscessus otomastoiditis is frequently complicated by adverse events. Management by a specialized team is recommended. Frequent clinical monitoring, regular blood tests, audiograms and ECGs are recommended. Prophylactic antiemetics should be administered due to the high frequency of nausea and vomiting, particularly with tigecycline.

背景：本研究旨在评估我们机构多学科临床途径治疗脓肿分枝杆菌的药物性不良事件，并对不良事件的监测和管理提出建议。方法：根据我们三级转诊中心公布的机构临床路径治疗的患者纳入。主要结局指标是记录的不良事件的类型和频率。此外，还评估了药物停止或中断的原因。结果：纳入10例患者，平均年龄8岁，男性占70%。所有患者均出现不良事件，90%的病例导致早产停药（40%）甚至停止使用一种或多种抗生素（70%）。最常见的不良事件是胃肠道（100%）、体重减轻（60%）、肝酶升高（70%）、低白蛋白血症（90%）和高甘油三酯血症（70%）。大多数不良事件可能由替加环素引起。所有患儿治疗后均临床痊愈，未发生长期身体不良事件。结论：多药治疗脓肿支原体耳乳突炎易并发不良事件。建议由专门的团队进行管理。建议经常进行临床监测，定期进行血液检查、听音图和心电图检查。由于恶心和呕吐的频率高，应给予预防性止吐药，特别是替加环素。

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引用次数: 0

Household button battery coating materials for injury prevention in esophageal impaction: An ex vivo porcine study 家用纽扣电池涂层材料预防食管嵌塞损伤：猪的离体研究。

IF 1.3 4区医学 Q3 OTORHINOLARYNGOLOGY

International journal of pediatric otorhinolaryngology

Pub Date : 2026-01-05 DOI: 10.1016/j.ijporl.2026.112713

Jacob G.J. Wihlidal , Elysia M. Grose , Yasmin Madan , Evan J. Propst , Adrian L. James , Jennifer M. Siu , Nikolaus E. Wolter

引用次数: 0

The effects of maturation on auditory brainstem response latencies and amplitudes using CE-Chirp® LS stimulus in a pediatric population 使用CE-Chirp®LS刺激的儿童人群成熟对听觉脑干反应潜伏期和振幅的影响

IF 1.3 4区医学 Q3 OTORHINOLARYNGOLOGY

International journal of pediatric otorhinolaryngology

Pub Date : 2026-01-05 DOI: 10.1016/j.ijporl.2026.112711

Büşra Kaynakoğlu , İrem Sendesen , Eser Sendesen

引用次数: 0

Associations between apnea-hypopnea index score and desaturation events during anesthesia induction in pediatric tonsillectomy patients: A retrospective analysis 儿童扁桃体切除术患者麻醉诱导时呼吸暂停低通气指数评分与去饱和事件的相关性：回顾性分析。

IF 1.3 4区医学 Q3 OTORHINOLARYNGOLOGY

International journal of pediatric otorhinolaryngology

Pub Date : 2026-01-05 DOI: 10.1016/j.ijporl.2026.112708

Sarah Kim , Bailey Balouch , Spencer Clements , Bryant Wang , Ajay Singh , Donald Solomon

引用次数: 0

The use of MEK inhibitors in pediatric patients presenting with respiratory distress and laryngeal Rosai-Dorfman Disease: Two case reports MEK抑制剂在以呼吸窘迫和喉部Rosai-Dorfman病为表现的儿科患者中的应用：两例报告

IF 1.3 4区医学 Q3 OTORHINOLARYNGOLOGY

International journal of pediatric otorhinolaryngology

Pub Date : 2026-01-05 DOI: 10.1016/j.ijporl.2026.112710

Sarah Van der Elst , Carolyn Fein Levy , Morris Edelman , Nika Finelt , Lee P. Smith , Neha A. Patel

引用次数: 0

Using artificial intelligence to rewrite the script on pediatric ENT patient education 用人工智能重写儿科耳鼻喉科患者教育的剧本

IF 1.3 4区医学 Q3 OTORHINOLARYNGOLOGY

International journal of pediatric otorhinolaryngology

Pub Date : 2026-01-05 DOI: 10.1016/j.ijporl.2026.112707

Andrew B. Brown , Kastley Marvin , Philip A. Gaudreau

引用次数: 0

Impact of anesthetics choice on auditory brainstem response testing in children: A systematic review 麻醉选择对儿童听觉脑干反应测试的影响：一项系统综述

IF 1.3 4区医学 Q3 OTORHINOLARYNGOLOGY

International journal of pediatric otorhinolaryngology

Pub Date : 2026-01-05 DOI: 10.1016/j.ijporl.2026.112714

Quan Lu , Loga Iyer , Surbhi Srinivas , Anita Jeyakumar

Objective

Critically appraise the literature for anesthetic agents and routes of administration and their impacts on successful sedation and auditory brainstem response (ABR) testing outcomes in children.

Methods

Searches of PubMed, Cochrane, and Web of Science for all available literature, last accessed February 2025, using “auditory brainstem response”, “anesthesia”, “anesthetic”, “IV anesthesia”, “volatile anesthesia”, “oral anesthesia”, “pediatric”, “sevoflurane”, and “hearing loss” with “AND”. Non-English, non-pediatric, studies unrelated to anesthetic agents and ABR were excluded.

Results

510 studies screened, 24 included (6053 patients (35.2 % female)). Eight studies with 282 patients reported the impact of different anesthetics on ABR waveforms, and sixteen with 5771 participants reported the rate of successful sedation. Sixty-nine patients from three studies demonstrated no significant difference in waveforms among different anesthetic agents. Four studies with 144 participants reported significant alterations of waveforms between pharmacologic and non-anesthetized groups. One study with 79 participants found that sevoflurane produced more false positives, resulting in more severe hearing loss diagnoses than propofol. Anesthetic agents with various routes of administration demonstrated different levels of efficacy in achieving sedation, with IV propofol and intranasal dexmedetomidine exhibiting improved performance.

Conclusion

Current literature demonstrates the use of multiple anesthetic agents and routes of administration during ABR testing in children with varying degrees of successful sedation and extent of impact on ABR waveforms. Limited data suggest that IV propofol is highly effective in achieving sedation with a lower impact on ABR testing outcomes. Nevertheless, further investigation is required to guide anesthetic selection during ABR testing in children.

目的对麻醉药物和给药途径及其对儿童成功镇静和听觉脑干反应（ABR）测试结果的影响进行批判性评价。方法检索PubMed、Cochrane和Web of Science所有可用文献，最后检索日期为2025年2月，检索词为“听觉脑干反应”、“麻醉”、“麻醉剂”、“静脉麻醉”、“挥发性麻醉”、“口腔麻醉”、“儿科”、“七氟烷”和“听力损失”。非英语、非儿科、与麻醉剂和ABR无关的研究被排除在外。结果510项研究被筛选，24项纳入（6053例患者，其中35.2%为女性）。8项涉及282例患者的研究报告了不同麻醉剂对ABR波形的影响，16项涉及5771名参与者的研究报告了镇静成功率。三个研究的69例患者显示不同麻醉剂的波形无显著差异。四项144名参与者的研究报告了药物组和非麻醉组之间波形的显著改变。一项有79名参与者的研究发现，七氟醚产生了更多的假阳性，导致比异丙酚更严重的听力损失诊断。不同给药途径的麻醉药在达到镇静效果方面表现出不同程度的疗效，静脉注射异丙酚和鼻内注射右美托咪定表现出更好的效果。结论目前的文献表明，在不同程度的成功镇静和对ABR波形的影响程度的儿童中，在ABR测试中使用多种麻醉剂和给药途径。有限的数据表明，静脉注射异丙酚在实现镇静方面非常有效，对ABR测试结果的影响较小。然而，需要进一步的研究来指导儿童ABR试验中麻醉剂的选择。

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引用次数: 0

Catastrophic primary bleeding post intracapsular tonsillectomy in paediatrics – highlighting risk and technical considerations 儿科扁桃体囊内切除术后的灾难性原发性出血-强调风险和技术考虑

IF 1.3 4区医学 Q3 OTORHINOLARYNGOLOGY

International journal of pediatric otorhinolaryngology

Pub Date : 2026-01-05 DOI: 10.1016/j.ijporl.2026.112706

Authors Amy Hannigan , Raimundo Garcia-Matte , Christopher Jackson , Hannah Burns , Eric Levi , Phillip Sale , Hayley Herbert

引用次数: 0

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