Pub Date : 2025-12-01DOI: 10.1016/j.ijporl.2025.112642
Liqiang Yang, Jinhong Zeng, Shuyao Qiu, Jianwen Zhong, Jinhong Huang, Min Zhi, Dabo Liu
{"title":"Corrigendum to “Application of the Das-Naglieri Cognitive Assessment System in children with sleep-disordered breathing” [Int. J. Pediatr. Otorhinolaryngol. 198 (2025) 112599]","authors":"Liqiang Yang, Jinhong Zeng, Shuyao Qiu, Jianwen Zhong, Jinhong Huang, Min Zhi, Dabo Liu","doi":"10.1016/j.ijporl.2025.112642","DOIUrl":"10.1016/j.ijporl.2025.112642","url":null,"abstract":"","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"199 ","pages":"Article 112642"},"PeriodicalIF":1.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145633379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-27DOI: 10.1016/j.ijporl.2025.112653
Yuşa Başoğlu , İlayda Başoğlu , Gül Ölçek
Objective
To compare teacher-reported socio-emotional and behavioral functioning in early-school-age children with cochlear implants (CI) versus normal-hearing (NH) peers using the Child Behavior Assessment Scale (CBAS), and to test whether group differences persist after adjustment for socioeconomic factors.
Methods
In this cross-sectional study, 80 children aged 5–6 years were enrolled (CI = 40; NH = 40). Teachers completed CBAS subscales (Adjustment, Social Anxiety, Rule-breaking Behaviors) and total score. Between-group comparisons used Mann–Whitney U tests. ANCOVA on CBAS total adjusted for maternal education, paternal education, and household income. Exploratory correlations within the CI group examined age and clinical durations.
Results
Compared with NH peers, the CI group showed lower Adjustment (mean ± SD: 61.45 ± 15.46 vs 80.95 ± 6.56; p < .001) and higher Social Anxiety (64.20 ± 13.27 vs 34.28 ± 7.02; p < .001) and Rule-breaking Behaviors (113.33 ± 26.77 vs 61.08 ± 15.98; p < .001). CBAS total was higher in the CI group (238.98 ± 48.22) than NH (176.30 ± 17.10; p < .001). In ANCOVA, the CI versus NH effect on CBAS total remained significant (F(1,75) = 33.846, p < .001; partial η2 = 0.311), while socioeconomic covariates were not significant. Within the CI group, child age correlated positively with Rule-breaking Behaviors (r = 0.331, p = .037).
Conclusions
At school entry children with CI showed higher levels of socio-emotional and behavioral difficulties compared to NH peers; however, these findings should be interpreted with caution given the sample size and cross-sectional design. The results support routine psychosocial surveillance and targeted supports within CI follow-up and school settings.
目的:使用儿童行为评估量表(CBAS)比较教师报告的早期耳蜗植入儿童(CI)与正常听力儿童(NH)的社会情绪和行为功能,并检验在调整社会经济因素后群体差异是否仍然存在。方法:本横断面研究纳入80例5-6岁儿童(CI = 40; NH = 40)。教师完成CBAS量表(适应、社交焦虑、违规行为)和总分。组间比较采用Mann-Whitney U检验。经母亲教育程度、父亲教育程度和家庭收入调整后的CBAS总方差。CI组的探索性相关性检查了年龄和临床持续时间。结果:CI组与NH组相比,调整率较低(mean±SD: 61.45±15.46 vs 80.95±6.56;p 2 = 0.311),而社会经济协变量无显著性差异。在CI组内,儿童年龄与违规行为呈正相关(r = 0.331, p = 0.037)。结论:在入学时,CI患儿比NH患儿表现出更高水平的社会情绪和行为困难;然而,考虑到样本量和横截面设计,这些发现应该谨慎解释。结果支持在CI随访和学校环境中进行常规社会心理监测和有针对性的支持。
{"title":"Behavioral and socio-emotional profiles in early-school-age children with cochlear implants versus normal-hearing peers","authors":"Yuşa Başoğlu , İlayda Başoğlu , Gül Ölçek","doi":"10.1016/j.ijporl.2025.112653","DOIUrl":"10.1016/j.ijporl.2025.112653","url":null,"abstract":"<div><h3>Objective</h3><div>To compare teacher-reported socio-emotional and behavioral functioning in early-school-age children with cochlear implants (CI) versus normal-hearing (NH) peers using the Child Behavior Assessment Scale (CBAS), and to test whether group differences persist after adjustment for socioeconomic factors.</div></div><div><h3>Methods</h3><div>In this cross-sectional study, 80 children aged 5–6 years were enrolled (CI = 40; NH = 40). Teachers completed CBAS subscales (Adjustment, Social Anxiety, Rule-breaking Behaviors) and total score. Between-group comparisons used Mann–Whitney U tests. ANCOVA on CBAS total adjusted for maternal education, paternal education, and household income. Exploratory correlations within the CI group examined age and clinical durations.</div></div><div><h3>Results</h3><div>Compared with NH peers, the CI group showed lower Adjustment (mean ± SD: 61.45 ± 15.46 vs 80.95 ± 6.56; p < .001) and higher Social Anxiety (64.20 ± 13.27 vs 34.28 ± 7.02; p < .001) and Rule-breaking Behaviors (113.33 ± 26.77 vs 61.08 ± 15.98; p < .001). CBAS total was higher in the CI group (238.98 ± 48.22) than NH (176.30 ± 17.10; p < .001). In ANCOVA, the CI versus NH effect on CBAS total remained significant (F(1,75) = 33.846, p < .001; partial η<sup>2</sup> = 0.311), while socioeconomic covariates were not significant. Within the CI group, child age correlated positively with Rule-breaking Behaviors (r = 0.331, p = .037).</div></div><div><h3>Conclusions</h3><div>At school entry children with CI showed higher levels of socio-emotional and behavioral difficulties compared to NH peers; however, these findings should be interpreted with caution given the sample size and cross-sectional design. The results support routine psychosocial surveillance and targeted supports within CI follow-up and school settings.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"200 ","pages":"Article 112653"},"PeriodicalIF":1.3,"publicationDate":"2025-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145677562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-27DOI: 10.1016/j.ijporl.2025.112655
Sruthi Surapaneni , Nikhil Rangarajan , Kyle Davis , Katherine Pletcher , Jeffrey Flowers , Graham Strub , Abby Nolder , Deanne King , Alexander P. Marston , Mark Vecchiotti , Kristan Alfonso , Sean Evans , Anita Deshpande , Kara Prickett , April Landry , Steven Goudy , Nandini Govil , Anna Messner , Gresham Richter , Andrew R. Scott , Courtney A. Hill
Introduction
Early and accurate diagnosis of middle ear effusion in primary care settings enables timely intervention, improving long-term patient outcomes while preventing overtreatment with antibiotics. Diagnosis requires assessment of tympanic membrane mobility, but this is hampered by access to and inexperience with pneumatic otoscopy or tympanometry. This research aims to train an artificial intelligence algorithm, using tympanic membrane images captured with consumer-grade otoscopes, to accurately predict the presence or absence of pediatric middle ear effusions.
Methods
Using an over-the-counter digital otoscope, tympanic membrane images were obtained from patients aged 6 months to 6 years old undergoing tympanostomy tube placement at 4 different institutions. The images were labeled according to the middle ear findings identified by pediatric otolaryngologists during myringotomy. A deep learning neural network was trained to classify tympanic membrane images as “Effusion” or “No Effusion”.
Results
From 219 patients, 537 tympanic membrane images were obtained. Serous, mucoid or purulent effusion were represented in 263 images and 273 images demonstrated no effusion. The trained model achieved a classification accuracy of 92.1 %, a sensitivity of 90.3 %, and specificity of 93.8 %.
Discussion
This model has a balanced sensitivity and specificity comparable to or surpassing pneumatic otoscopy (94 % sensitivity, 80 % specificity) and tympanometry (90–94 % sensitivity, 50–75 % specificity). With current barriers to using the diagnostic tools recommended in clinical guidelines, it is evident that an inexpensive, objective diagnostic aid is needed for the primary care setting. This model's performance demonstrates the first step toward an accessible tool for primary care providers.
{"title":"Artificial intelligence classification of pediatric middle ear effusion using consumer-grade otoscopes","authors":"Sruthi Surapaneni , Nikhil Rangarajan , Kyle Davis , Katherine Pletcher , Jeffrey Flowers , Graham Strub , Abby Nolder , Deanne King , Alexander P. Marston , Mark Vecchiotti , Kristan Alfonso , Sean Evans , Anita Deshpande , Kara Prickett , April Landry , Steven Goudy , Nandini Govil , Anna Messner , Gresham Richter , Andrew R. Scott , Courtney A. Hill","doi":"10.1016/j.ijporl.2025.112655","DOIUrl":"10.1016/j.ijporl.2025.112655","url":null,"abstract":"<div><h3>Introduction</h3><div>Early and accurate diagnosis of middle ear effusion in primary care settings enables timely intervention, improving long-term patient outcomes while preventing overtreatment with antibiotics. Diagnosis requires assessment of tympanic membrane mobility, but this is hampered by access to and inexperience with pneumatic otoscopy or tympanometry. This research aims to train an artificial intelligence algorithm, using tympanic membrane images captured with consumer-grade otoscopes, to accurately predict the presence or absence of pediatric middle ear effusions.</div></div><div><h3>Methods</h3><div>Using an over-the-counter digital otoscope, tympanic membrane images were obtained from patients aged 6 months to 6 years old undergoing tympanostomy tube placement at 4 different institutions. The images were labeled according to the middle ear findings identified by pediatric otolaryngologists during myringotomy. A deep learning neural network was trained to classify tympanic membrane images as “Effusion” or “No Effusion”.</div></div><div><h3>Results</h3><div>From 219 patients, 537 tympanic membrane images were obtained. Serous, mucoid or purulent effusion were represented in 263 images and 273 images demonstrated no effusion. The trained model achieved a classification accuracy of 92.1 %, a sensitivity of 90.3 %, and specificity of 93.8 %.</div></div><div><h3>Discussion</h3><div>This model has a balanced sensitivity and specificity comparable to or surpassing pneumatic otoscopy (94 % sensitivity, 80 % specificity) and tympanometry (90–94 % sensitivity, 50–75 % specificity). With current barriers to using the diagnostic tools recommended in clinical guidelines, it is evident that an inexpensive, objective diagnostic aid is needed for the primary care setting. This model's performance demonstrates the first step toward an accessible tool for primary care providers.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"200 ","pages":"Article 112655"},"PeriodicalIF":1.3,"publicationDate":"2025-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145668334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Patient education empowers patients to control their own health and care. Taking responsibility of own hearing is important for children with hearing loss to navigate effectively in noisy environments at school. However, children must never stand alone with this responsibility. Raising positive awareness about hearing might enhance teachers' and classmates’ understanding of hearing loss, making them more competent in supporting children with hearing loss to achieve the best possible listening conditions.
In this study we explored how to create positive and timely awareness of hearing loss in middle- and secondary school. We developed a playful virtual reality game about the hearing sense and tested a setup that was suitable for group-use in classrooms. A total of 538 pupils between 10 and 16 years of age, including 26 children with hearing loss, participated in the study. Pupils, teachers and speech and language pathologists from the schools evaluated the game positively, and test before and after intervention showed a significant effect of learning. However, our study also highlighted that some children experience symptoms of cybersickness that shall not be ignored. Furthermore, implementing virtual reality in mainstream schools may present challenges in terms of economic costs and limited teacher resources.
Educational gaming certainly has the potential to support learning in schools, but future studies must investigate if virtual reality or other digital platforms are the best solution.
{"title":"Virtual reality to create positive and timely awareness of hearing loss in middle- and secondary school","authors":"Signe Wischmann , Lærke Hammer , Lone Jantzen , Tanja Pihl Sandager , Nete Rudbeck Kamper , Signe Toftgaard Henriksen , Ali Adjorlu , Stefania Serafin , Per Cayé-Thomasen , Lone Percy-Smith","doi":"10.1016/j.ijporl.2025.112660","DOIUrl":"10.1016/j.ijporl.2025.112660","url":null,"abstract":"<div><div>Patient education empowers patients to control their own health and care. Taking responsibility of own hearing is important for children with hearing loss to navigate effectively in noisy environments at school. However, children must never stand alone with this responsibility. Raising positive awareness about hearing might enhance teachers' and classmates’ understanding of hearing loss, making them more competent in supporting children with hearing loss to achieve the best possible listening conditions.</div><div>In this study we explored how to create positive and timely awareness of hearing loss in middle- and secondary school. We developed a playful virtual reality game about the hearing sense and tested a setup that was suitable for group-use in classrooms. A total of 538 pupils between 10 and 16 years of age, including 26 children with hearing loss, participated in the study. Pupils, teachers and speech and language pathologists from the schools evaluated the game positively, and test before and after intervention showed a significant effect of learning. However, our study also highlighted that some children experience symptoms of cybersickness that shall not be ignored. Furthermore, implementing virtual reality in mainstream schools may present challenges in terms of economic costs and limited teacher resources.</div><div>Educational gaming certainly has the potential to support learning in schools, but future studies must investigate if virtual reality or other digital platforms are the best solution.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"200 ","pages":"Article 112660"},"PeriodicalIF":1.3,"publicationDate":"2025-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145648584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-25DOI: 10.1016/j.ijporl.2025.112656
Vincent J. Heck , Peer Eysel , Tobias Prasse , Max J. Scheyerer , Katrin Eysel-Gosepath
Purpose
Grisel Syndrome (GS) describes a rare, non-traumatic atlantoaxial rotatory subluxation in children typically associated with upper respiratory tract infection, or otorhinolaryngological surgery. The aim of this study was to systematically review the literature regarding interdisciplinary treatment approaches, consequences of delayed or misdiagnosed GS, and upper cervical deformities resulting from misdiagnosed GS. Additionally, we share our institutional experience with this pathology.
Methods
We queried our institutional database for patients suffering from GS which were treated in our department between 2001 and 2024. A systematic literature search was conducted using Medline and the Cochrane Library, following PRISMA guidelines.
Results
Our database revealed three patients with GS. One patient with misdiagnosed of GS presented with rigid occipital rotation, ultimately progressing to occipito-atlantoaxial rotatory dislocation (OAARD). Two patients were early diagnosed and successfully treated with halo vest immobilization. The systematic literature review identified 13 cases of OAARD across 12 reports. Etiologies included upper respiratory infections, otorhinolaryngological surgery, juvenile idiopathic arthritis, and minor trauma. The average time to diagnosis of OAARD was 5.9 months (0.5–18 months). The treatment involved occipito-atlantal fusion (43 %), atlantoaxial fusion with halo vest (29 %), or traction followed by halo vest (21 %).
Conclusion
GS and OAARD are underrecognized and often diagnosed late, causing irreversible deformity and permanent loss of upper cervical spine mobility. Painful torticollis following upper respiratory tract infection, otorhinolaryngological surgery, or minor trauma should be treated as GS until proven otherwise. Early recognition and interdisciplinary treatment are crucial to prevent progression and avoid invasive surgical interventions.
{"title":"The Grisel Syndrome: early interdisciplinary treatment needed to prevent severe upper cervical deformity - Experience from a high-volume spine center and systematic review of existing literature","authors":"Vincent J. Heck , Peer Eysel , Tobias Prasse , Max J. Scheyerer , Katrin Eysel-Gosepath","doi":"10.1016/j.ijporl.2025.112656","DOIUrl":"10.1016/j.ijporl.2025.112656","url":null,"abstract":"<div><h3>Purpose</h3><div>Grisel Syndrome (GS) describes a rare, non-traumatic atlantoaxial rotatory subluxation in children typically associated with upper respiratory tract infection, or otorhinolaryngological surgery. The aim of this study was to systematically review the literature regarding interdisciplinary treatment approaches, consequences of delayed or misdiagnosed GS, and upper cervical deformities resulting from misdiagnosed GS. Additionally, we share our institutional experience with this pathology.</div></div><div><h3>Methods</h3><div>We queried our institutional database for patients suffering from GS which were treated in our department between 2001 and 2024. A systematic literature search was conducted using Medline and the Cochrane Library, following PRISMA guidelines.</div></div><div><h3>Results</h3><div>Our database revealed three patients with GS. One patient with misdiagnosed of GS presented with rigid occipital rotation, ultimately progressing to occipito-atlantoaxial rotatory dislocation (OAARD). Two patients were early diagnosed and successfully treated with halo vest immobilization. The systematic literature review identified 13 cases of OAARD across 12 reports. Etiologies included upper respiratory infections, otorhinolaryngological surgery, juvenile idiopathic arthritis, and minor trauma. The average time to diagnosis of OAARD was 5.9 months (0.5–18 months). The treatment involved occipito-atlantal fusion (43 %), atlantoaxial fusion with halo vest (29 %), or traction followed by halo vest (21 %).</div></div><div><h3>Conclusion</h3><div>GS and OAARD are underrecognized and often diagnosed late, causing irreversible deformity and permanent loss of upper cervical spine mobility. Painful torticollis following upper respiratory tract infection, otorhinolaryngological surgery, or minor trauma should be treated as GS until proven otherwise. Early recognition and interdisciplinary treatment are crucial to prevent progression and avoid invasive surgical interventions.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"200 ","pages":"Article 112656"},"PeriodicalIF":1.3,"publicationDate":"2025-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145617529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
To evaluate the impact of the coronavirus disease (COVID-19) pandemic and public health measures, including emergency declarations and reclassification of COVID-19, on pediatric adenoidectomy (Ad) volume and referrals diagnosed with adenoidal hypertrophy (AH) accompanied by obstructive sleep apnea (OSA) and/or otitis media with effusion (OME) in Japan.
Methods
Monthly case volumes from January 2019 to December 2024 were analyzed at a regional tertiary hospital. Trends were assessed for pediatric Ad, new referrals, general anesthesia surgeries (all departments and ENT), and regional COVID-19 cases. Ad cases were classified according to the presence of concomitant tonsillectomy (T) or tympanostomy tube insertion (TTI); referrals based on the presence of OSA or OME symptoms. The annual age trends were also evaluated.
Results
General anesthesia surgeries across the hospital and in the adult ENT department declined temporarily during the emergency declarations but rapidly recovered afterward, whereas those in the pediatric ENT department remained below the baseline even after each declaration. Notably, Ad volumes showed no apparent post-declaration recoveries and remained suppressed until 2023, except for a transient increase in summer 2021, followed by a sharp rebound after the COVID-19 reclassification. In 2024, the volumes of Ad with concurrent T and referrals for AH with OSA or OME symptoms both exceeded the pre-pandemic baseline. Surgical age declined during the pandemic, while referral age remained stable until 2023. Both ages increased in 2024.
Conclusion
The total Ad volume—especially Ad with concurrent T—and referrals for AH with OSA symptoms showed an abrupt decline immediately after the pandemic onset, followed by a sharp recovery exceeding pre-pandemic levels. These findings suggest that public health crises can disrupt elective care for chronic pediatric conditions and that the post-pandemic surge reflects behavioral changes and pent-up demand as well as possible epidemiological alterations in tonsillar tissue dynamics.
{"title":"Longitudinal impact of the coronavirus disease pandemic on pediatric adenoidectomy volume and referrals in Japan: A 6-year retrospective study","authors":"Makoto Ogawa , Takeshi Maruta , Takefumi Kamakura , Yusuke Otami , Takato Sudo , Hiroto Fujita , Nozomi Fujisawa , Shusuke Okamoto , Maki Yamashita , Suzuyo Okazaki , Kiyohito Hosokawa , Yasuo Mishiro","doi":"10.1016/j.ijporl.2025.112654","DOIUrl":"10.1016/j.ijporl.2025.112654","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the impact of the coronavirus disease (COVID-19) pandemic and public health measures, including emergency declarations and reclassification of COVID-19, on pediatric adenoidectomy (Ad) volume and referrals diagnosed with adenoidal hypertrophy (AH) accompanied by obstructive sleep apnea (OSA) and/or otitis media with effusion (OME) in Japan.</div></div><div><h3>Methods</h3><div>Monthly case volumes from January 2019 to December 2024 were analyzed at a regional tertiary hospital. Trends were assessed for pediatric Ad, new referrals, general anesthesia surgeries (all departments and ENT), and regional COVID-19 cases. Ad cases were classified according to the presence of concomitant tonsillectomy (T) or tympanostomy tube insertion (TTI); referrals based on the presence of OSA or OME symptoms. The annual age trends were also evaluated.</div></div><div><h3>Results</h3><div>General anesthesia surgeries across the hospital and in the adult ENT department declined temporarily during the emergency declarations but rapidly recovered afterward, whereas those in the pediatric ENT department remained below the baseline even after each declaration. Notably, Ad volumes showed no apparent post-declaration recoveries and remained suppressed until 2023, except for a transient increase in summer 2021, followed by a sharp rebound after the COVID-19 reclassification. In 2024, the volumes of Ad with concurrent T and referrals for AH with OSA or OME symptoms both exceeded the pre-pandemic baseline. Surgical age declined during the pandemic, while referral age remained stable until 2023. Both ages increased in 2024.</div></div><div><h3>Conclusion</h3><div>The total Ad volume—especially Ad with concurrent T—and referrals for AH with OSA symptoms showed an abrupt decline immediately after the pandemic onset, followed by a sharp recovery exceeding pre-pandemic levels. These findings suggest that public health crises can disrupt elective care for chronic pediatric conditions and that the post-pandemic surge reflects behavioral changes and pent-up demand as well as possible epidemiological alterations in tonsillar tissue dynamics.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"200 ","pages":"Article 112654"},"PeriodicalIF":1.3,"publicationDate":"2025-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145617530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-24DOI: 10.1016/j.ijporl.2025.112657
John W. Hunsicker , Megan Ballard , Ashoke Khanwalkar , Todd M. Wine , Mark A. Lovell , Alexandra G. Suttman , Kami Wolfe Schneider , Kenny H. Chan
Introduction
Nasal chondromesenchymal hamartoma (NCMH) is a rare benign tumor of the nasal cavity and paranasal sinuses. Its clinical relevance has increased following the discovery of its association with DICER1 syndrome—a genetic condition predisposing individuals to multiple neoplasms. These two cases highlight important clinical extremes of this disease entity and offer practical evaluation and management recommendations for practicing otolaryngologists.
Methods
A retrospective review was conducted from 1999 to 2025 at a single institution. The report includes two female teenagers presented at ages 13 and 17 years, respectively, diagnosed with NCMH—one with and one without DICER1 syndrome. Key outcomes included recurrence rates, anatomical spread, genetic testing results (including evaluation for DICER1 variants), and disease-status at follow-up. A thorough literature review on NCMH and DICER1 syndrome was conducted to provide the reader with management recommendations.
Results
•
Case 1. A 13-year-old female with NCMH in the left ethmoid sinus underwent complete surgical resection and had no pathogenic DICER1 variants detected. No recurrence was observed after 3 years.
•
Case 2. A 17-year-old female with DICER1 syndrome experienced multiple recurrences of NCMH after initial diagnosis, requiring five surgical resections. She had bilateral disease and skull base involvement. She remains disease-free one year after her last surgery.
Conclusions
Genetic testing for DICER1 variants should be standard in all newly diagnosed NCMH cases. Annual nasal endoscopic and imaging follow up is recommended in all individuals with a constitutional or mosaic pathogenic DICER1 variant. There is no published guidance for recurrent NCMH at the olfactory groove/cribriform plate region. Conservative local excisions should be pursued for tumor recurrences.
{"title":"Otolaryngologic evaluation and management of nasal chondromesenchymal hamartoma","authors":"John W. Hunsicker , Megan Ballard , Ashoke Khanwalkar , Todd M. Wine , Mark A. Lovell , Alexandra G. Suttman , Kami Wolfe Schneider , Kenny H. Chan","doi":"10.1016/j.ijporl.2025.112657","DOIUrl":"10.1016/j.ijporl.2025.112657","url":null,"abstract":"<div><h3>Introduction</h3><div>Nasal chondromesenchymal hamartoma (NCMH) is a rare benign tumor of the nasal cavity and paranasal sinuses. Its clinical relevance has increased following the discovery of its association with DICER1 syndrome—a genetic condition predisposing individuals to multiple neoplasms. These two cases highlight important clinical extremes of this disease entity and offer practical evaluation and management recommendations for practicing otolaryngologists.</div></div><div><h3>Methods</h3><div>A retrospective review was conducted from 1999 to 2025 at a single institution. The report includes two female teenagers presented at ages 13 and 17 years, respectively, diagnosed with NCMH—one with and one without DICER1 syndrome. Key outcomes included recurrence rates, anatomical spread, genetic testing results (including evaluation for <em>DICER1</em> variants), and disease-status at follow-up. A thorough literature review on NCMH and DICER1 syndrome was conducted to provide the reader with management recommendations.</div></div><div><h3>Results</h3><div><ul><li><span>•</span><span><div><strong>Case 1</strong><strong>.</strong> A 13-year-old female with NCMH in the left ethmoid sinus underwent complete surgical resection and had no pathogenic <em>DICER1</em> variants detected. No recurrence was observed after 3 years.</div></span></li><li><span>•</span><span><div><strong>Case 2</strong><strong>.</strong> A 17-year-old female with DICER1 syndrome experienced multiple recurrences of NCMH after initial diagnosis, requiring five surgical resections. She had bilateral disease and skull base involvement. She remains disease-free one year after her last surgery.</div></span></li></ul></div></div><div><h3>Conclusions</h3><div>Genetic testing for <em>DICER1</em> variants should be standard in all newly diagnosed NCMH cases. Annual nasal endoscopic and imaging follow up is recommended in all individuals with a constitutional or mosaic pathogenic <em>DICER1</em> variant. There is no published guidance for recurrent NCMH at the olfactory groove/cribriform plate region. Conservative local excisions should be pursued for tumor recurrences.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"200 ","pages":"Article 112657"},"PeriodicalIF":1.3,"publicationDate":"2025-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145668339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acute bacterial rhinosinusitis is frequently seen in children. While complications are uncommon, they can be serious. Risk factors associated with complicated cases remain poorly defined. This study aimed primarily to identify predictors of complications in pediatric rhinosinusitis. Secondary objectives included evaluating factors associated with treatment failure and the occurrence of severe complications.
Methods
We conducted a retrospective study of all children hospitalized for acute sinusitis at Limoges University Hospital between 2010 and 2020. Data on demographics, medical history, clinical presentation, laboratory tests, and imaging were collected. Statistical analyses included multivariate logistic regression.
Results
A total of 109 patients were included. Asthma and prior use of NSAIDs were associated with higher risk of complications. Elevated CRP and lymphopenia were significant biological indicators of severity. Anaerobic Streptococci were more often associated with severe cases.
Conclusion
Asthma, NSAID use, and high CRP levels appear to be reliable indicators of complications in pediatric acute bacterial rhinosinusitis. These findings support the need for clinical vigilance and early imaging in such cases.
{"title":"Study of prognostic factors for complicated acute rhinosinusitis in children","authors":"Abdulaziz Alghamdi , Karine Aubry , Lucie Cussinet , Florian Bonnafous","doi":"10.1016/j.ijporl.2025.112650","DOIUrl":"10.1016/j.ijporl.2025.112650","url":null,"abstract":"<div><h3>Introduction</h3><div>Acute bacterial rhinosinusitis is frequently seen in children. While complications are uncommon, they can be serious. Risk factors associated with complicated cases remain poorly defined. This study aimed primarily to identify predictors of complications in pediatric rhinosinusitis. Secondary objectives included evaluating factors associated with treatment failure and the occurrence of severe complications.</div></div><div><h3>Methods</h3><div>We conducted a retrospective study of all children hospitalized for acute sinusitis at Limoges University Hospital between 2010 and 2020. Data on demographics, medical history, clinical presentation, laboratory tests, and imaging were collected. Statistical analyses included multivariate logistic regression.</div></div><div><h3>Results</h3><div>A total of 109 patients were included. Asthma and prior use of NSAIDs were associated with higher risk of complications. Elevated CRP and lymphopenia were significant biological indicators of severity. Anaerobic Streptococci were more often associated with severe cases.</div></div><div><h3>Conclusion</h3><div>Asthma, NSAID use, and high CRP levels appear to be reliable indicators of complications in pediatric acute bacterial rhinosinusitis. These findings support the need for clinical vigilance and early imaging in such cases.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"199 ","pages":"Article 112650"},"PeriodicalIF":1.3,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145569817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-20DOI: 10.1016/j.ijporl.2025.112652
Yuan Wang , Jikai Zhu , Danni Wang , Shouqin Zhao
Objective
To evaluate the long-term safety, efficacy, and satisfaction of Bonebridge implantation in children under 12 years.
Methods
This retrospective study followed 34 patients (aged 5.4–11.8 years) who underwent Bonebridge implantation between 2016 and 2020, with a median follow-up of 55 months. Audiological outcomes, including pure-tone audiometry (PTA), speech reception thresholds (SRTs), speech discrimination scores (SDSs), and sound field hearing thresholds (SFHTs) were assessed. Adverse events and patient-reported satisfaction (HDSS) were recorded.
Results
Bonebridge significantly improved speech perception (SRT: −6.20 dB in unilateral; −0.18 dB in bilateral) and SFHT (mean improvement: 20.80 dB unilateral; 29.07 dB bilateral). SDS for monosyllables, disyllables, and sentences showed substantial gains in aided conditions. Adverse events were mild to moderate, except for one serious device failure resolved with revision surgery. Sound localization accuracy decreased in patients with bilateral hearing loss who used a unilateral Bonebridge due to unilateral auditory stimulation. Patient satisfaction was high, with bilateral hearing loss reporting longer daily usage.
Conclusion
Bonebridge is a safe and effective intervention for young children under 12 years with conductive hearing loss, enhancing auditory access and quality of life.
{"title":"Long-term safety and audiological results with the Bone Conduction Implant 601 in children younger than 12 years old","authors":"Yuan Wang , Jikai Zhu , Danni Wang , Shouqin Zhao","doi":"10.1016/j.ijporl.2025.112652","DOIUrl":"10.1016/j.ijporl.2025.112652","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the long-term safety, efficacy, and satisfaction of Bonebridge implantation in children under 12 years.</div></div><div><h3>Methods</h3><div>This retrospective study followed 34 patients (aged 5.4–11.8 years) who underwent Bonebridge implantation between 2016 and 2020, with a median follow-up of 55 months. Audiological outcomes, including pure-tone audiometry (PTA), speech reception thresholds (SRTs), speech discrimination scores (SDSs), and sound field hearing thresholds (SFHTs) were assessed. Adverse events and patient-reported satisfaction (HDSS) were recorded.</div></div><div><h3>Results</h3><div>Bonebridge significantly improved speech perception (SRT: −6.20 dB in unilateral; −0.18 dB in bilateral) and SFHT (mean improvement: 20.80 dB unilateral; 29.07 dB bilateral). SDS for monosyllables, disyllables, and sentences showed substantial gains in aided conditions. Adverse events were mild to moderate, except for one serious device failure resolved with revision surgery. Sound localization accuracy decreased in patients with bilateral hearing loss who used a unilateral Bonebridge due to unilateral auditory stimulation. Patient satisfaction was high, with bilateral hearing loss reporting longer daily usage.</div></div><div><h3>Conclusion</h3><div>Bonebridge is a safe and effective intervention for young children under 12 years with conductive hearing loss, enhancing auditory access and quality of life.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"199 ","pages":"Article 112652"},"PeriodicalIF":1.3,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145569815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}