International journal of pediatric otorhinolaryngology最新文献

英文中文

Early detection of congenital cytomegalovirus – universal screening in the neonatal ICU 先天性巨细胞病毒的早期检测——新生儿重症监护病房的普遍筛查。

IF 1.3 4区医学 Q3 OTORHINOLARYNGOLOGY

International journal of pediatric otorhinolaryngology

Pub Date : 2026-02-01 Epub Date: 2026-01-10 DOI: 10.1016/j.ijporl.2026.112712

Avani Vasireddy , Monica Ogunsusi , Rick Pittman , Kristin Weimer , Eileen Raynor

引用次数: 0

Hearing aids for otitis media with effusion in children: practicality and cost 儿童积液性中耳炎助听器的实用性和成本

IF 1.3 4区医学 Q3 OTORHINOLARYNGOLOGY

International journal of pediatric otorhinolaryngology

Pub Date : 2026-02-01 Epub Date: 2025-12-22 DOI: 10.1016/j.ijporl.2025.112687

Oliver Greenwood , Jim Harrigan , Haytham Kubba

引用次数: 0

Safety and tolerability of a standardized treatment regimen for Mycobacterium abscessus otomastoiditis 脓肿分枝杆菌耳乳突炎标准化治疗方案的安全性和耐受性。

IF 1.3 4区医学 Q3 OTORHINOLARYNGOLOGY

International journal of pediatric otorhinolaryngology

Pub Date : 2026-02-01 Epub Date: 2026-01-06 DOI: 10.1016/j.ijporl.2026.112715

Theresa Y.S. Leow , Stijn Bekkers , Stefanie S.V. Henriet , Myrthe K.S. Hol , Arno M. Janssen , Thijs T.G. Jansen , Henricus P.M. Kunst , Sjoert A.H. Pegge , Jerome J. Waterval , Jakko van Ingen , Koen J. Van Aerde

Background

This study aims to evaluate the drug-induced adverse events of our institutional multidisciplinary clinical pathway for M. abscessus treatment and gives suggestions for monitoring and management of adverse events.

Methods

Patients treated according to a published institutional clinical pathway in our tertiary referral centre were included. Main outcome measures were the type and frequency of adverse events documented. In addition, reasons for drug cessation or interruption were evaluated.

Results

Ten patients were included (mean age: 8 years old; male: 70 %). All patients suffered from adverse events, in 90 % of the cases leading to pre-term drug interruption (40 %) or even cessation (70 %) of one or more antibiotics. Most common adverse events were gastrointestinal (100 %), weight loss (60 %), elevated liver enzymes (70 %), hypoalbuminemia (90 %) and hypertriglyceridemia (70 %). Most adverse events were likely caused by tigecycline. All children were clinically cured after the treatment and did not suffer from long-term physical adverse events.

Conclusions

The multidrug treatment for M. abscessus otomastoiditis is frequently complicated by adverse events. Management by a specialized team is recommended. Frequent clinical monitoring, regular blood tests, audiograms and ECGs are recommended. Prophylactic antiemetics should be administered due to the high frequency of nausea and vomiting, particularly with tigecycline.

背景：本研究旨在评估我们机构多学科临床途径治疗脓肿分枝杆菌的药物性不良事件，并对不良事件的监测和管理提出建议。方法：根据我们三级转诊中心公布的机构临床路径治疗的患者纳入。主要结局指标是记录的不良事件的类型和频率。此外，还评估了药物停止或中断的原因。结果：纳入10例患者，平均年龄8岁，男性占70%。所有患者均出现不良事件，90%的病例导致早产停药（40%）甚至停止使用一种或多种抗生素（70%）。最常见的不良事件是胃肠道（100%）、体重减轻（60%）、肝酶升高（70%）、低白蛋白血症（90%）和高甘油三酯血症（70%）。大多数不良事件可能由替加环素引起。所有患儿治疗后均临床痊愈，未发生长期身体不良事件。结论：多药治疗脓肿支原体耳乳突炎易并发不良事件。建议由专门的团队进行管理。建议经常进行临床监测，定期进行血液检查、听音图和心电图检查。由于恶心和呕吐的频率高，应给予预防性止吐药，特别是替加环素。

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引用次数: 0

The effects of maturation on auditory brainstem response latencies and amplitudes using CE-Chirp® LS stimulus in a pediatric population 使用CE-Chirp®LS刺激的儿童人群成熟对听觉脑干反应潜伏期和振幅的影响

IF 1.3 4区医学 Q3 OTORHINOLARYNGOLOGY

International journal of pediatric otorhinolaryngology

Pub Date : 2026-02-01 Epub Date: 2026-01-05 DOI: 10.1016/j.ijporl.2026.112711

Büşra Kaynakoğlu , İrem Sendesen , Eser Sendesen

引用次数: 0

Associations between apnea-hypopnea index score and desaturation events during anesthesia induction in pediatric tonsillectomy patients: A retrospective analysis 儿童扁桃体切除术患者麻醉诱导时呼吸暂停低通气指数评分与去饱和事件的相关性：回顾性分析。

IF 1.3 4区医学 Q3 OTORHINOLARYNGOLOGY

International journal of pediatric otorhinolaryngology

Pub Date : 2026-02-01 Epub Date: 2026-01-05 DOI: 10.1016/j.ijporl.2026.112708

Sarah Kim , Bailey Balouch , Spencer Clements , Bryant Wang , Ajay Singh , Donald Solomon

引用次数: 0

Role of acoustic rhinometry in assessing severe adenoid hypertrophy in children with obstructive sleep apnea syndrome 声学鼻测量在评估阻塞性睡眠呼吸暂停综合征儿童严重腺样体肥大中的作用

IF 1.3 4区医学 Q3 OTORHINOLARYNGOLOGY

International journal of pediatric otorhinolaryngology

Pub Date : 2026-02-01 Epub Date: 2025-12-30 DOI: 10.1016/j.ijporl.2025.112703

Lin Su, Jun Xu, Zilong He, Guiliang Huang, Mingrong Nie, Changzhi Sun

引用次数: 0

Outcomes of sialendoscopy in the management of juvenile recurrent parotitis: A systematic review and meta-analysis 涎腺内窥镜治疗青少年复发性腮腺炎的结果：系统回顾和荟萃分析

IF 1.3 4区医学 Q3 OTORHINOLARYNGOLOGY

International journal of pediatric otorhinolaryngology

Pub Date : 2026-02-01 Epub Date: 2025-12-21 DOI: 10.1016/j.ijporl.2025.112690

Raisa Chowdhury , Ostap Orishchak , Nasser K. Almutairi , Mark Khoury , Sabrina Wurzba , Sam J. Daniel

引用次数: 0

Volumetric airway changes in adolescents treated with mini-screw assisted rapid palatal expansion (MARPE) 迷你螺钉辅助快速腭扩张（MARPE）治疗青少年气道容量改变。

IF 1.3 4区医学 Q3 OTORHINOLARYNGOLOGY

International journal of pediatric otorhinolaryngology

Pub Date : 2026-02-01 Epub Date: 2025-12-28 DOI: 10.1016/j.ijporl.2025.112705

R Nithin Vaishag , Sapna Varma N.K , Renuka Balu , Rahul D. Prabha , Ajith V.V

Objective

Reduced airway dimensions of the upper pharynx due to transverse maxillary deficiency has a prevalence of 18 % among young adults. Bone anchored palatal expansion with miniscrew assisted rapid maxillary expansion (MARPE) appliance has expanded the envelope of treatment options available to treat maxillary constriction in adolescents and young adults. The purpose of the study was to evaluate the volumetric changes in airway dimensions following MARPE and to correlate clinical airway changes using flexible nasopharyngoscopy.

Methods

Ten adolescents (aged 15–20 years) with transverse maxillary deficiency satisfying the inclusion criteria were selected for the study and treated with MARPE. The changes with MARPE in dental, skeletal, and airway dimensions were evaluated clinically and radiographically with flexible nasopharyngoscopy and cone-beam computed tomography (CBCT) respectively. The volumetric changes were compared using paired sample t-test and the change in airway collapse was compared using Pearson Chi-square test.

Results

A significant increase in intermolar distance, interpremolar distance, maxillary inter-buccal and inter-lingual distance, molar bucco-lingual angulation, nasopharyngeal volume, and total airway volume was seen post expansion. Oropharyngeal volume and minimum cross-sectional area, showed a volumetric increase. Clinical evaluation showed a significant improvement in the airway collapse at the level of oropharynx. This corresponded with the findings of the radiographic evaluation.

Conclusion

The study results showed a significant improvement in nasopharyngeal and total airway volume following MARPE with significant improvement in pharyngeal airway in the region of oropharynx. MARPE can be recommended as a promising therapy for airway constriction in adolescents and young adults.

目的：上颌横向缺陷导致的上咽气道尺寸缩小在年轻人中有18%的患病率。骨锚定腭扩张与微型辅助快速上颌扩张器（MARPE）扩大了治疗方案的范围，可用于治疗上颌缩窄的青少年和年轻人。本研究的目的是评估MARPE术后气道尺寸的体积变化，并利用柔性鼻咽喉镜观察临床气道变化的相关性。方法：选择10例15 ~ 20岁符合纳入标准的上颌横向缺损青少年进行MARPE治疗。通过鼻咽镜和锥形束计算机断层扫描（CBCT）分别评估MARPE患者口腔、骨骼和气道尺寸的临床和影像学变化。容积变化比较采用配对样本t检验，气道塌陷变化比较采用Pearson卡方检验。结果：扩张后磨牙间距离、释磨牙距离、上颌颊间和舌间距离、磨牙颊舌成角、鼻咽容积和气道总容积显著增加。口咽容积和最小横截面积均呈体积增大。临床评估显示，在口咽水平的气道塌陷明显改善。这与影像学检查结果一致。结论：本研究结果显示MARPE术后鼻咽部和气道总容积均有显著改善，口咽部咽道改善明显。MARPE是一种很有前途的治疗青少年和年轻人气道狭窄的方法。

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引用次数: 0

Recurrent post-tonsillectomy bleeding in pediatric patients 小儿扁桃体切除术后复发性出血。

IF 1.3 4区医学 Q3 OTORHINOLARYNGOLOGY

International journal of pediatric otorhinolaryngology

Pub Date : 2026-02-01 Epub Date: 2026-01-11 DOI: 10.1016/j.ijporl.2026.112720

Kathleen R. Billings , Sydney J. Sachse , Saied Ghadersohi , Achilles A. Kanaris , Rachel L. Schappacher , Rachel D. Yoon , Alexander J. Szymczak , Inbal Hazkani

Objective

Post-tonsillectomy hemorrhage is a common risk after tonsillectomy. The goal of this study is to analyze the rate of recurrent PTH (R-PTH), and to determine potential risk factors for recurrent bleeding.

Methods

Retrospective cohort study of patients <18 years of age evaluated at a tertiary care pediatric hospital for PTH. Risk factors for patients with R-PTH episodes were evaluated, when compared to patients with a single bleeding episode. An assessment of healthcare utilization in those with R-PTH was performed.

Results

Among 18,819 tonsillectomies performed in the study period, 382 (2.0 %) had a PTH. Of these, 42 patients (11.0 %) experienced R-PTH: 35 patients (9.2 %) with two bleeding episodes, and 7 patients (1.8 %) with three. Patients with R-PTH were male (n = 26, 61.9 %), Hispanic/Latino (n = 19, 45.2 %), and English-speaking (n = 33, 78.6 %). The overall risk of R-PTH following tonsillectomy was 0.2 %, and the relative risk of R-PTH after an initial PTH was 5.4 times. None of the factors analyzed were found to have a significant association with R-PTH, although a greater proportion of patients with R-PTH were found to have a history of chronic tonsillitis (21.4 % vs 14.4 %). Healthcare utilization, an aggregate measurement of primary care, otolaryngology, telemedicine, and emergency department visits unrelated to PTH, was significantly higher in R-PTH patients (2.5 vs. 1.8 occurrences, p = 0.023).

Conclusions

The rate of R-PTH was small (0.2 %), although those patients with an initial PTH had a relative risk of 5.4 for a R-PTH episode. No clear risk factors for R-PTH were identified. Increased healthcare utilization was noted in those with R-PTH.

Level of evidence

目的：扁桃体切除术后出血是扁桃体切除术后常见的危险。本研究的目的是分析甲状旁腺激素（R-PTH）的复发率，并确定出血复发的潜在危险因素。方法：回顾性队列研究患者结果：在研究期间18,819例扁桃体切除术中，382例（2.0%）有PTH。其中，42例患者（11.0%）经历了甲状旁腺激素：35例患者（9.2%）有两次出血发作，7例患者（1.8%）有三次出血发作。R-PTH患者为男性（n = 26，占61.9%）、西班牙裔/拉丁裔（n = 19，占45.2%）和英语患者（n = 33，占78.6%）。扁桃体切除术后R-PTH的总风险为0.2%，而初始PTH后R-PTH的相对风险为5.4倍。虽然有较大比例的R-PTH患者有慢性扁桃体炎病史（21.4% vs 14.4%），但分析的所有因素均未发现与R-PTH有显著关联。与甲状旁腺激素无关的初级保健、耳鼻喉科、远程医疗和急诊科就诊的综合测量结果显示，r -甲状旁腺激素患者的医疗利用率明显更高（2.5比1.8,p = 0.023）。结论：尽管初始PTH患者发生R-PTH发作的相对风险为5.4，但R-PTH的发生率很小（0.2%）。没有明确的促甲状旁腺激素的危险因素。在有促性甲状旁腺激素的患者中，医疗保健利用率增加。证据等级：4；

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引用次数: 0

The use of MEK inhibitors in pediatric patients presenting with respiratory distress and laryngeal Rosai-Dorfman Disease: Two case reports MEK抑制剂在以呼吸窘迫和喉部Rosai-Dorfman病为表现的儿科患者中的应用：两例报告

IF 1.3 4区医学 Q3 OTORHINOLARYNGOLOGY

International journal of pediatric otorhinolaryngology

Pub Date : 2026-02-01 Epub Date: 2026-01-05 DOI: 10.1016/j.ijporl.2026.112710

Sarah Van der Elst , Carolyn Fein Levy , Morris Edelman , Nika Finelt , Lee P. Smith , Neha A. Patel

引用次数: 0

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