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Advancing neonatal hearing screening in Latin America: Insights from pediatric otolaryngologists 推动拉丁美洲新生儿听力筛查:儿科耳鼻喉科医生的见解。
IF 1.2 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-10-05 DOI: 10.1016/j.ijporl.2024.112122
Daniel Peñaranda , Riley Hue Vo , Tania Sih , Graciela Gonzalez Franco , Tulio A. Valdez

Objective

To assess the real-world application of legislative measures and regulations governing newborn hearing testing in Latin America.

Methods

An online survey was sent to the Interamerican Association of Pediatric Otorhinolaryngology (IAPO) network to investigate neonatal hearing screening practices. Twelve questions were asked about legislation, implementation, and barriers to neonatal hearing screening.

Results

A total of 89 pediatric otolaryngologists representing 20 Latin American nations participated in this survey. The majority of respondents (64 %) indicated the existence of neonatal hearing laws within their respective countries and correctly named the specific legislation. However, it is noteworthy that over half (58 %) of pediatric ear, nose, and throat specialists reported that these laws are not consistently put into practice in their daily clinical routines. Respondents from five countries disclosed that neonatal hearing screening is not conducted within the first month of an infant’s life.

Conclusions

While the majority of Latin American nations have established legislation concerning neonatal hearing screening, its application in clinical practice is lacking due to economic obstacles. Marked disparities across Latin America persist for neonatal hearing screening. Our study provides key insights and recommendations aimed at addressing these issues, including the need for stronger legislative enforcement, increased funding, improved infrastructure, targeted professional training, and expanded public education to strengthen this vital aspect of healthcare in Latin America.
目的:评估拉丁美洲新生儿听力测试立法措施和法规的实际应用情况:评估拉丁美洲新生儿听力检测立法措施和法规的实际应用情况:向美洲小儿耳鼻喉科协会(IAPO)网络发送了一份在线调查,调查新生儿听力筛查的实践情况。调查共提出了 12 个问题,涉及新生儿听力筛查的立法、实施和障碍:共有 89 名儿科耳鼻喉科医生参与了此次调查,他们分别来自 20 个拉丁美洲国家。大多数受访者(64%)表示各自国家有新生儿听力法律,并正确说出了具体的法律名称。但值得注意的是,超过半数(58%)的儿科耳鼻喉科专家表示,这些法律并没有在他们的日常临床工作中得到贯彻执行。来自五个国家的受访者透露,新生儿听力筛查没有在婴儿出生后的第一个月内进行:结论:虽然大多数拉美国家都制定了有关新生儿听力筛查的法律,但由于经济障碍,这些法律在临床实践中并没有得到应用。拉丁美洲各国在新生儿听力筛查方面仍存在明显差距。我们的研究为解决这些问题提供了重要的见解和建议,包括需要加强立法执行力度、增加资金投入、改善基础设施、开展有针对性的专业培训和扩大公众教育,以加强拉丁美洲医疗保健的这一重要方面。
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引用次数: 0
Barriers to auditory brainstem response testing under anesthesia 麻醉状态下听觉脑干反应测试的障碍。
IF 1.2 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-09-29 DOI: 10.1016/j.ijporl.2024.112124
Alexandra E. Tunkel , Anisa Benbourenane , Hengameh K. Behzadpour , Md Sohel Rana , Tracey Ambrose , Eve Kronzek , Diego A. Preciado , Brian K. Reilly

Objective

Auditory brainstem response (ABR) testing is the gold standard for diagnosis of hearing loss in children who cannot complete behavioral audiometry. Testing under general anesthesia is often recommended when natural sleep ABR and/or behavioral audiometry are unsuccessful. This study aims to determine which demographic and patient factors serve as barriers to receiving this diagnostic testing.

Methods

A retrospective chart review from an internal database of patients who underwent ABR testing under anesthesia from 2017 to 2023 was completed. Patient demographics, clinical diagnoses, dates of initial recommendation, and dates of testing were recorded.

Results

A total of 395 patients met inclusion criteria, with a median time from initial evaluation to successful ABR under anesthesia of 5.1 months (range 0.1–209 months). This time was significantly higher in patients with public insurance compared to private insurance and in patients with the following medical complexities: cardiac disease, developmental delay, neurologic disease, eye disease, and genetic syndromes not associated with hearing loss. The interval was significantly shorter in patients with abnormal ear anatomy.

Conclusion

Patient factors, such as insurance type and certain medical diagnoses, may lead to delayed ABR testing under anesthesia and thus delayed diagnosis and management of hearing loss. This has implications for the timely care and treatment of children with hearing loss.
目的:听性脑干反应(ABR)测试是诊断无法完成行为测听的儿童听力损失的金标准。当自然睡眠 ABR 和/或行为测听不成功时,通常建议在全身麻醉下进行测试。本研究旨在确定哪些人口统计学因素和患者因素是接受这种诊断测试的障碍:从内部数据库中对 2017 年至 2023 年期间在麻醉状态下接受 ABR 测试的患者进行回顾性病历审查。结果:共有 395 名患者符合纳入条件:共有 395 名患者符合纳入标准,从初步评估到麻醉下成功 ABR 的中位时间为 5.1 个月(范围为 0.1-209 个月)。与参加私人保险的患者相比,参加公共保险的患者所需的时间明显更长,患有以下复杂疾病的患者所需的时间也明显更长:心脏病、发育迟缓、神经系统疾病、眼部疾病以及与听力损失无关的遗传综合征。在耳部解剖异常的患者中,间隔时间明显更短:结论:患者因素(如保险类型和某些医疗诊断)可能会导致麻醉下 ABR 测试延迟,从而延误听力损失的诊断和治疗。这对及时护理和治疗听力损失儿童具有重要意义。
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引用次数: 0
Linguistic analysis of letters of recommendation for pediatric otolaryngology: A pilot study 小儿耳鼻喉科推荐信的语言分析:试点研究。
IF 1.2 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-09-27 DOI: 10.1016/j.ijporl.2024.112121
Taylor Loth , Rebecca Compton , Zahrah Taufique , Andrew Redmann , Brianne Barnett Roby

Objectives

To analyze the language of letters of recommendation for pediatric otolaryngology fellowship for possible gender and/or racial bias. To refine methodology for future investigation of gender and language within letters of recommendation for pediatric otolaryngology fellowship.

Methods

Practicing pediatric otolaryngologists were recruited as survey participants. A total of 10 letters of recommendation were screened to represent an equal number of applicants who identify as male and female and an equal number of applicants who identify as White and applicants who identify as Black, Indigenous, or a Person of Color. Names, pronouns, location, and other identifying information were removed from the letters. Survey participants were asked to read each letter and categorize the applicant's gender and race as well as that of the letter writer. The letters were also subject to analysis by WordStat linguistic software.

Results

A total of 35 pediatric otolaryngologists participated in the survey. Participants assigned gender of the applicant correctly in 43 % of letters and gender of the letter writer correctly in 53 % of letters. Race of the applicant was judged correctly in 65 % of letters. Participants indicated words such as caring, hard-working, and prepared led them to assume the applicant was female, which was corroborated by linguistic analysis. No such words were identified as predictive of race.

Conclusion

This pilot study suggests that while there are certain linguistic associations with gender among applications to pediatric otolaryngology fellowship, they may not impact biases held by the reader. This is relevant given a recent rise in the number of female applicants to this subspecialty and ongoing unfilled fellowship positions. Future studies are needed to determine if such associations exist and ultimately affect match potential and success within the field. These studies will require analysis of more letters and with more survey respondents, along with a higher in-depth linguistic analysis.

Lay summary

This pilot study aims to evaluate letters of recommendation for pediatric otolaryngology fellowship applications for gender bias with the goal of outlining future studies. There were certain words associated with a given gender, which could impact applicants’ potential to match.

Level of evidence

NA.
目的分析小儿耳鼻喉科研究员推荐信的语言,以发现可能存在的性别和/或种族偏见。完善今后调查小儿耳鼻喉科研究员推荐信中的性别和语言的方法:招募儿科耳鼻喉科执业医师作为调查对象。共筛选了 10 封推荐信,其中男性和女性申请人人数相等,白人和黑人、土著或有色人种申请人人数相等。信件中的姓名、代词、地点和其他身份识别信息均已删除。调查参与者被要求阅读每封信,并对申请人的性别和种族以及写信人的性别和种族进行分类。这些信件还通过 WordStat 语言软件进行了分析:共有 35 名儿科耳鼻喉科医生参与了调查。在 43% 的信件中,参与者对申请人性别的判断是正确的;在 53% 的信件中,参与者对写信人性别的判断是正确的。65%的信件正确判断了申请人的种族。参与者表示,关爱、勤奋和有准备等词语会让他们认为申请人是女性,这一点在语言分析中得到了证实。没有发现此类词语可以预测种族:这项试验性研究表明,虽然在小儿耳鼻喉科研究员的申请中,性别与语言有一定的联系,但它们可能不会影响读者的偏见。考虑到最近申请该亚专科的女性人数增加以及目前尚未填补的研究员职位,这一点很有意义。今后还需要进行研究,以确定这种关联是否存在,并最终影响匹配潜力和在该领域的成功。这些研究将需要对更多的信件和更多的调查对象进行分析,并进行更深入的语言分析。报告摘要:本试验性研究旨在评估小儿耳鼻喉科研究金申请推荐信中的性别偏见,目的是勾勒出未来研究的轮廓。有一些词与特定性别相关,这可能会影响申请人的匹配潜力:不适用。
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引用次数: 0
Comprehensive management of chronic ear disease: Consecutive patient analysis at a tertiary children's hospital 慢性耳病的综合治疗:一家三级儿童医院的连续患者分析。
IF 1.2 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-09-25 DOI: 10.1016/j.ijporl.2024.112118
Michael D. Puricelli

Objective

To characterize medical complexity and advanced interventions necessary to treat pediatric patients with chronic ear disease.

Methods

A retrospective case review of children who received surgery for chronic otitis media, cholesteatoma, or tympanic membrane perforation at a tertiary children's hospital from 2020 to 2024 was performed. The frequency and type of medical complexities as well as distribution and success of advanced otologic interventions were recorded.

Results

Operations were performed on 80 ears. Forty-five percent were in medically complex patients. Twenty-five percent had a syndrome, 13 % had American Society for Anesthesiologists Severity Class 3 or more, and 38 % attended multi-disciplinary programs. Advanced audiology testing protocols were utilized in 53 % of patients, and multiple children received complex sleep and airway operations. Advanced surgical techniques were required in 58 %. Post-operatively, an intact tympanic membrane was achieved in 95 % of operated ears (p < 0.01). Residual and recurrent cholesteatoma were each present in 5 % of cases, with mean follow-up of 11.6 months. Otorrhea reduced from 64 % of patients pre-operatively to 2 % post-operatively (p < 0.01), including cessation in all individuals who reported social/bullying issues related to ear drainage/odor. Unrestricted water exposure was achieved in 99 % of individuals (p < 0.01). Patients showed a mean improvement after surgery of 7.6 dB, as measured by the change in air-bone gap (p < 0.05). Conclusions: Comprehensive treatment of otologic conditions included care that was holistic of all medical needs, integrated with other services, developmentally appropriate, encompassing of non-otologic procedures, technically advanced, effective, and functionally-focused. Surgical teams should endeavor together to provide this combination of services.
摘要方法:对 2020 年至 2020 年期间在三级儿童医院接受慢性中耳炎、胆脂瘤或鼓膜穿孔手术的儿童病例进行回顾性分析:对一家三级儿童医院 2020 年至 2024 年期间因慢性中耳炎、胆脂瘤或鼓膜穿孔接受手术治疗的儿童病例进行回顾性研究。研究记录了复杂病症的发生频率和类型,以及先进耳科介入手术的分布和成功率:结果:对 80 只耳朵进行了手术。45%的患者病情复杂。25%的患者患有综合征,13%的患者属于美国麻醉医师协会严重程度3级或以上,38%的患者参加了多学科项目。53%的患者使用了高级听力测试协议,多名儿童接受了复杂的睡眠和气道手术。58%的患者需要使用先进的手术技术。术后,95% 的手术耳朵鼓膜完好无损(P 结论):耳科疾病的综合治疗包括全面满足所有医疗需求、与其他服务相结合、适合儿童发展、包含非耳科手术、技术先进、有效且注重功能的护理。手术团队应共同努力,提供这种综合服务。
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引用次数: 0
Correlations between clinical parameters and PSQ in children with suspected OSA 疑似 OSA 儿童的临床参数与 PSQ 之间的相关性。
IF 1.2 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-09-25 DOI: 10.1016/j.ijporl.2024.112120
Laura Jelušić , Hrvoje Vidić , Andrijana Včeva , Željko Zubčić , Hrvoje Mihalj , Zlatko Kljajić , Ivan Abičić , Kristina Kralik , Tihana Mendeš
The aim of this study was to measure tonsils and adenoid vegetations, investigate the modified Mallampati score, determine BMI according to body mass and corresponding percentile, and compare these data with the results of the Pediatric Sleep Questionnaire (PSQ). The subjects were children aged 2 to 18 who were indicated for adenotonsillectomy at the Clinic for Otorhinolaryngology and Head and Neck Surgery. A doctor specialist conducted the clinical examinations. According to the PSQ, 75 subjects were divided into two groups: those at high risk and those at low risk for developing obstructive sleep apnea (OSA). The PSQ results showed that 45 subjects (60 %) were at high risk for OSA, and these subjects had significantly lower weight and BMI. Although a higher number of subjects had grade 4 tonsils and grade 3 and 4 adenoids, this distribution was not statistically significant. There was no statistically significant difference in the distribution of the modified Mallampati score when compared with the PSQ results. Lower body mass and BMI were statistically significant risk factors for OSA, while the size of the tonsils and adenoids, as well as the modified Mallampati score, did not show any statistically significant difference in comparison with the PSQ results.
本研究的目的是测量扁桃体和腺样体,调查改良的马兰帕蒂评分,根据体重和相应的百分位数确定体重指数,并将这些数据与儿科睡眠问卷(PSQ)的结果进行比较。受试者为耳鼻咽喉头颈外科诊所的腺扁桃体切除术适应症患儿,年龄在 2 至 18 岁之间。由一名专科医生进行临床检查。根据 PSQ,75 名受试者被分为两组:患阻塞性睡眠呼吸暂停(OSA)的高风险组和低风险组。PSQ 结果显示,45 名受试者(60%)属于 OSA 高危人群,这些受试者的体重和体重指数明显较低。虽然有较多受试者的扁桃体为 4 级,腺样体为 3 级和 4 级,但这一分布在统计学上并不显著。与 PSQ 结果相比,改良 Mallampati 评分的分布在统计学上没有明显差异。较低的体重和体重指数在统计学上是导致 OSA 的重要风险因素,而扁桃体和腺样体的大小以及修正的 Mallampati 评分与 PSQ 的结果相比,在统计学上没有显著差异。
{"title":"Correlations between clinical parameters and PSQ in children with suspected OSA","authors":"Laura Jelušić ,&nbsp;Hrvoje Vidić ,&nbsp;Andrijana Včeva ,&nbsp;Željko Zubčić ,&nbsp;Hrvoje Mihalj ,&nbsp;Zlatko Kljajić ,&nbsp;Ivan Abičić ,&nbsp;Kristina Kralik ,&nbsp;Tihana Mendeš","doi":"10.1016/j.ijporl.2024.112120","DOIUrl":"10.1016/j.ijporl.2024.112120","url":null,"abstract":"<div><div>The aim of this study was to measure tonsils and adenoid vegetations, investigate the modified Mallampati score, determine BMI according to body mass and corresponding percentile, and compare these data with the results of the Pediatric Sleep Questionnaire (PSQ). The subjects were children aged 2 to 18 who were indicated for adenotonsillectomy at the Clinic for Otorhinolaryngology and Head and Neck Surgery. A doctor specialist conducted the clinical examinations. According to the PSQ, 75 subjects were divided into two groups: those at high risk and those at low risk for developing obstructive sleep apnea (OSA). The PSQ results showed that 45 subjects (60 %) were at high risk for OSA, and these subjects had significantly lower weight and BMI. Although a higher number of subjects had grade 4 tonsils and grade 3 and 4 adenoids, this distribution was not statistically significant. There was no statistically significant difference in the distribution of the modified Mallampati score when compared with the PSQ results. Lower body mass and BMI were statistically significant risk factors for OSA, while the size of the tonsils and adenoids, as well as the modified Mallampati score, did not show any statistically significant difference in comparison with the PSQ results.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"186 ","pages":"Article 112120"},"PeriodicalIF":1.2,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142371799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Retrospective Study Distinguishing between Hyperacusis and Misophonia in children with Auditory Processing Disorder (APD) 区分听觉处理障碍(APD)儿童听力过强和失音的回顾性研究
IF 1.2 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-09-21 DOI: 10.1016/j.ijporl.2024.112119
Ansar Ahmmed, Sabarinath Vijayakumar

Objectives

Decreased sound tolerance (DST) is common in children with auditory processing disorder (APD). This study aimed to differentiate between hyperacusis and misophonia in children with APD.

Design

A retrospective study evaluating outcomes of structured history and co-morbidity following Research Domain Criteria (RDoC) frame-work. Misophonia was considered as oversensitivity to eating/chewing sounds and hyperacusis as oversensitivity to other sounds.

Study sample

Two hundred and seventy-nine children (160 males; 119 females), 6-16 year-olds with NVIQ ≥80, diagnosed with APD between January 2021 and December 2022.

Results

One hundred and forty-three out of 279 children with APD had DST, of which 107 had hyperacusis (without misophonia) and 36 had misophonia. Misophonia co-existed with hyperacusis in 35 children (97 %), and in one child misophonia occurred without hyperacusis. Misophonia was prevalent in older children, in females, and those with tinnitus. Fear and being upset were predominant emotional responses in hyperacusis (without misophonia) while disgust and verbal abuse were prevalent in misophonia (with or without hyperacusis). Compared to children without DST, the hyperacusis (without misophonia) and misophonia (with or without hyperacusis) groups had significant higher prevalence of ADHD, anxiety, and language impairment. Educational difficulties were similar in APD irrespective of the presence or absence of DST. Despite higher tinnitus prevalence in misophonia (with or without hyperacusis) along with similar co-morbidities and educational difficulties in both hyperacusis (without misophonia) and misophonia (with or without hyperacusis), the misophonia (with or without hyperacusis) group surprisingly had less support at school which was reflected in fewer Education, Health and Care Plan (EHCP).

Conclusions

In APD misophonia mostly co-exists with hyperacusis, with differences in emotional responses, tinnitus prevalence, and gender distribution when compared to hyperacusis (without misophonia). Increase in awareness about misophonia is needed, as children with misophonia may have unidentified needs. Larger scale prospective study is required to clarify if misophonia evolves from hyperacusis, and to explore the factors underlying ‘misophonia with hyperacusis’ and ‘misophonia without hyperacusis’. For clarity, DST studies need to specify if hyperacusis or misophonia co-existed when referring to hyperacusis or misophonia.
目标听觉处理障碍(APD)儿童普遍存在声音耐受性降低(DST)的情况。本研究旨在区分听觉处理障碍儿童中的过度听力障碍和失音。研究样本2021年1月至2022年12月期间被诊断为APD的6至16岁儿童(160名男性;119名女性),NVIQ≥80。结果279名APD儿童中有143名患有DST,其中107名患有听力障碍(无失音),36名患有失音。有 35 名儿童(97%)患有听力障碍,其中有一名儿童患有听力障碍,但没有听力障碍。失音症主要发生在年龄较大的儿童、女性和有耳鸣的儿童身上。恐惧和不安是听力障碍儿童的主要情绪反应(不伴有失音),而厌恶和辱骂则是失音儿童的主要情绪反应(伴有或不伴有听力障碍)。与没有听力障碍的儿童相比,听力障碍过重(无听力障碍)组和听力障碍过轻(有或无听力障碍)组的多动症、焦虑症和语言障碍发病率明显更高。无论是否存在 DST,APD 患者在教育方面遇到的困难相似。尽管听力障碍(伴有或不伴有听力亢进)患者的耳鸣发生率较高,而且听力亢进(不伴有听力障碍)和听力障碍(伴有或不伴有听力亢进)患者的合并疾病和教育困难相似,但令人惊讶的是,听力障碍(伴有或不伴有听力亢进)组患者在学校获得的支持较少,这反映在较少的教育、健康和护理计划(EHCP)中。结论 在自闭症患者中,失音症大多与听力障碍同时存在,与听力障碍(无失音症)相比,在情绪反应、耳鸣发生率和性别分布方面存在差异。需要提高对误听症的认识,因为患有误听症的儿童可能有一些未被发现的需求。需要进行更大规模的前瞻性研究,以明确失音症是否由听力障碍演变而来,并探讨 "伴有听力障碍的失音症 "和 "不伴有听力障碍的失音症 "的基本因素。为明确起见,DST 研究在提及听力过高或听力障碍时,需要说明是听力过高还是听力障碍同时存在。
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引用次数: 0
The AMSA® manosonic nebulizer for ENT disease among children in Poland 用于治疗波兰儿童耳鼻喉疾病的 AMSA® manosonic 雾化吸入器
IF 1.2 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-09-20 DOI: 10.1016/j.ijporl.2024.112113
Magdalena Beata Skarżyńska , Elżbieta Gos , Milaine Dominici Sanfins , Patryk Hartwich , Piotr Henryk Skarżyński , Agata Szkiełkowska
<div><h3>Introduction</h3><div>The AMSA® manosonic nebulizer uses acoustic vibration and a flow of air to create an aerosol from a solution or suspension of a drug. The aerosol created this way is claimed to have enhanced penetration and drug delivery. It is administered under short-term overpressure, meaning that the aerosol is able to penetrate into the middle ear through the Eustachian tube (ET).</div></div><div><h3>Purpose</h3><div>of the study: The aim of this study is to identify the active substances used in AMSA® manosonic nebulization for treating common ENT diseases in children aged 2–17 years and to evaluate the overall effectiveness of AMSA® manosonic nebulization in this context. Assessments were done by comparing conditions before and after nebulization using the following tests: (1) Eustachian tube function test, (2) tympanometry, and (3) otoscopy.</div></div><div><h3>Material and methods</h3><div>This study was a retrospective study with ethics committee consent. 129 children, comprising 56 girls and 73 boys. They were aged between 2 and 17 years, with a mean age of 6.9 years (SD = 3.0). There were 74 children up to 6 years and 55 children over 6 years of age. Children had the following conditions: (1) chronic otitis media with effusion, OME (n = 86), (2) Eustachian tube dysfunction, ETD (n = 34) (3) Other conditions (e.g. cholesteatoma, retraction pocket), (n = 9). Combination of medicines administered in this study was: Budesonide + ambroxol (with or without NaCl), Budesonide (with or without NaCl), Budesonide + N-acetylcysteine (with or without NaCl), Budesonide + hyaluronic acid, Budesonide + ambroxol (with hyaluronic acid), Ambroxol (with or without NaCl).</div></div><div><h3>Results</h3><div>The number of nebulizations ordered was between 1 and 20 treatments, but most commonly, pa-tients were given a nebulization series of 10 treatments. This was the case for 80.6 % of the patients. Most patients with OME and ETD had 10 treatments ordered (79 % and 79.5 %, respectively), while all patients with other conditions had 10 treatments. Analysis of the tympanometry results was done in terms of the number of affected ears (not by individual). There were 210 ears with complete tympanometry (both pre and post), including 142 ears with OME, 54 with ETD, and 14 others. Statistically significant changes (improvements) after AMSA nebulizations were found for statistic compliance and middle ear pressure. Otoscopy assessments were done in all ears. The results were abnormal in 155 ears (73.8 %) and normal in 55 ears (26.2 %). After AMSA nebulizations, the number of abnormal results decreased to 117 ears (55.7 %) and normal results were found in 93 ears (44.7 %).</div></div><div><h3>Conclusion</h3><div>Use of the AMSA manosonic nebulizer appears to be an effective way of improving chronic medical conditions in children – such as chronic otitis media with effusion and Eustachian tube defect – but only if patient compliance can be achieved. Th
简介 AMSA® manosonic 雾化器利用声波振动和气流将药物溶液或悬浮液制成气溶胶。据称,以这种方式产生的气溶胶具有更强的渗透性和给药性。它是在短期超压的情况下给药的,这意味着气雾剂能够通过咽鼓管(ET)渗入中耳:本研究旨在确定 AMSA® manosonic 雾化疗法中用于治疗 2-17 岁儿童常见耳鼻喉疾病的活性物质,并评估 AMSA® manosonic 雾化疗法在这方面的总体效果。通过比较雾化前后的情况,使用以下测试进行评估:(1) 咽鼓管功能测试;(2) 鼓室测量法;(3) 耳镜检查。129 名儿童中包括 56 名女孩和 73 名男孩。他们的年龄在 2 到 17 岁之间,平均年龄为 6.9 岁(SD = 3.0)。其中 6 岁以下儿童 74 名,6 岁以上儿童 55 名。儿童患有以下疾病:(1)慢性中耳炎伴流脓(OME,n = 86);(2)咽鼓管功能障碍(ETD,n = 34);(3)其他疾病(如胆脂瘤、回缩袋)(n = 9)。本研究中的联合用药为布地奈德+氨溴索(含或不含氯化钠)、布地奈德(含或不含氯化钠)、布地奈德+N-乙酰半胱氨酸(含或不含氯化钠)、布地奈德+透明质酸、布地奈德+氨溴索(含透明质酸)、氨溴索(含或不含氯化钠)。80.6%的患者都是这种情况。大多数 OME 和 ETD 患者都接受了 10 次治疗(分别为 79% 和 79.5%),而所有其他疾病患者都接受了 10 次治疗。对鼓室测量结果的分析是按受影响耳朵的数量进行的(而不是按个人)。共有 210 只耳朵进行了完整的鼓室测量(包括治疗前和治疗后),其中包括 142 只患有 OME 的耳朵、54 只患有 ETD 的耳朵和 14 只其他耳朵。经AMSA雾化治疗后,统计顺应性和中耳压力均有明显改善。对所有耳朵进行了耳镜检查。结果显示,155 只耳朵(73.8%)异常,55 只耳朵(26.2%)正常。结论使用 AMSA 人工渗液雾化器似乎是改善儿童慢性疾病(如慢性中耳炎伴渗液和咽鼓管缺损)的有效方法,但前提是患者必须遵从医嘱。最常用的活性物质是布地奈德,与是否使用额外的分泌物/褐质溶解剂无关。
{"title":"The AMSA® manosonic nebulizer for ENT disease among children in Poland","authors":"Magdalena Beata Skarżyńska ,&nbsp;Elżbieta Gos ,&nbsp;Milaine Dominici Sanfins ,&nbsp;Patryk Hartwich ,&nbsp;Piotr Henryk Skarżyński ,&nbsp;Agata Szkiełkowska","doi":"10.1016/j.ijporl.2024.112113","DOIUrl":"10.1016/j.ijporl.2024.112113","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Introduction&lt;/h3&gt;&lt;div&gt;The AMSA® manosonic nebulizer uses acoustic vibration and a flow of air to create an aerosol from a solution or suspension of a drug. The aerosol created this way is claimed to have enhanced penetration and drug delivery. It is administered under short-term overpressure, meaning that the aerosol is able to penetrate into the middle ear through the Eustachian tube (ET).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Purpose&lt;/h3&gt;&lt;div&gt;of the study: The aim of this study is to identify the active substances used in AMSA® manosonic nebulization for treating common ENT diseases in children aged 2–17 years and to evaluate the overall effectiveness of AMSA® manosonic nebulization in this context. Assessments were done by comparing conditions before and after nebulization using the following tests: (1) Eustachian tube function test, (2) tympanometry, and (3) otoscopy.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Material and methods&lt;/h3&gt;&lt;div&gt;This study was a retrospective study with ethics committee consent. 129 children, comprising 56 girls and 73 boys. They were aged between 2 and 17 years, with a mean age of 6.9 years (SD = 3.0). There were 74 children up to 6 years and 55 children over 6 years of age. Children had the following conditions: (1) chronic otitis media with effusion, OME (n = 86), (2) Eustachian tube dysfunction, ETD (n = 34) (3) Other conditions (e.g. cholesteatoma, retraction pocket), (n = 9). Combination of medicines administered in this study was: Budesonide + ambroxol (with or without NaCl), Budesonide (with or without NaCl), Budesonide + N-acetylcysteine (with or without NaCl), Budesonide + hyaluronic acid, Budesonide + ambroxol (with hyaluronic acid), Ambroxol (with or without NaCl).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;The number of nebulizations ordered was between 1 and 20 treatments, but most commonly, pa-tients were given a nebulization series of 10 treatments. This was the case for 80.6 % of the patients. Most patients with OME and ETD had 10 treatments ordered (79 % and 79.5 %, respectively), while all patients with other conditions had 10 treatments. Analysis of the tympanometry results was done in terms of the number of affected ears (not by individual). There were 210 ears with complete tympanometry (both pre and post), including 142 ears with OME, 54 with ETD, and 14 others. Statistically significant changes (improvements) after AMSA nebulizations were found for statistic compliance and middle ear pressure. Otoscopy assessments were done in all ears. The results were abnormal in 155 ears (73.8 %) and normal in 55 ears (26.2 %). After AMSA nebulizations, the number of abnormal results decreased to 117 ears (55.7 %) and normal results were found in 93 ears (44.7 %).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;div&gt;Use of the AMSA manosonic nebulizer appears to be an effective way of improving chronic medical conditions in children – such as chronic otitis media with effusion and Eustachian tube defect – but only if patient compliance can be achieved. Th","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"186 ","pages":"Article 112113"},"PeriodicalIF":1.2,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142319883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pediatric parathyroid carcinoma and hyperparathyroidism-jaw tumor syndrome: A case report and literature review 小儿甲状旁腺癌和甲状旁腺功能亢进-颌骨肿瘤综合征:病例报告和文献综述
IF 1.2 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-09-18 DOI: 10.1016/j.ijporl.2024.112116
Harrison M. Thompson , Mikayla G. Hubbard , Sarah A. Ackah , Alden Dewey , Erika Zevin , Erik A. Imel , Boaz Kamazyn , Monali Lipman , Adeyinka O. Akinsanya , L. Daniel Wurtz , Diane W. Chen
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引用次数: 0
A multicentre observational study of paediatric head and neck abscesses 儿科头颈部脓肿多中心观察研究
IF 1.2 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-09-17 DOI: 10.1016/j.ijporl.2024.112117
Timothy Davies , Anne Markey , Noor Janjua , Jacquline Chan , Kate Stephenson , Heather Newport , Thushita Kunanandam , Christine English , Jaya Nichani , Kade Harbert , Eishaan Bhargava , Miran Pankhania , Ayla Tabaksert , Steven Powell , Emily Davis , Richard Brown , Rhodri Costello , Jack Sandeman , Sarah O'Donnell , Mary Consunji , Madhankumar Krishnan

Introduction

In winter of 2022/3 paediatric ENT surgeons across the UK observed that the incidence of severe abscesses in the head and neck and associated complications was higher than seen in previous years. We aimed to collate and evaluate data from across the UK to establish if this was a true rise in cases, and to describe the factors associated.

Methods

A multicentre retrospective data collection was undertaken from 13 units across the UK. Patients admitted between September 2022–February 2023 with a head and neck abscess including sinogenic, otogenic, deep and superficial neck abscesses were included. Demographic, disease specific, management and outcome data were collected. Hospital episode statistic data were also requested and analysed to allow for comparison with previous 10 years of head and neck abscesses.

Results

262 patients with abscesses of the head and neck were admitted during the study period, 100 between September and November and 163 between December and February. Mastoid abscesses were the most common abscess across both groups. The rate of group A streptococcus + culture results rose significantly from 12 % in autumn group to 30 % in winter (p = 0.02). The rate of intracranial complications rose from 10 % to 18 % (p = 0.11) and the rate of venous thrombosis rose over the same timeframe from 3 % to 14 % (p = 0.01).

Discussion

This study demonstrated a statistically significant rise in the rate of group A streptococcus associated abscesses when comparing Autumn and Winter 2022/2023. Over the same timeframe a statistically significant rise in the proportion of patients with venous thromboses associated with H&N abscesses was noted. Interestingly, despite perceived national consensus regarding a spike in abscess incidence, the number of abscesses seen in winter 2022/2023 was in keeping with expected rates of paediatric H&N abscesses, based on pre covid year-on-year rise in incidence.
导言2022年3月的冬天,英国各地的儿童耳鼻喉外科医生发现,头颈部严重脓肿和相关并发症的发病率比往年要高。我们旨在整理和评估英国各地的数据,以确定病例数是否真的增加,并描述相关因素。研究纳入了2022年9月至2023年2月期间收治的头颈部脓肿患者,包括窦源性、耳源性、深层和浅层颈部脓肿。收集了人口统计学、特定疾病、管理和结果数据。研究期间共收治了262名头颈部脓肿患者,其中100名是在9月至11月期间收治的,163名是在12月至次年2月期间收治的。乳突脓肿是两组中最常见的脓肿。A组链球菌+培养结果的比例从秋季组的12%显著上升到冬季组的30%(p = 0.02)。颅内并发症的发生率从 10% 上升到 18%(p = 0.11),静脉血栓的发生率在同一时间范围内从 3% 上升到 14%(p = 0.01)。 讨论这项研究表明,与 2022/2023 年秋季和冬季相比,A 组链球菌相关脓肿的发生率有明显的统计学上升。在同一时间段内,与 H&N 脓肿相关的静脉血栓患者比例也出现了统计学意义上的显著上升。有趣的是,尽管全国一致认为脓毒症发病率会激增,但根据发病率的同比增长趋势,2022/2023 年冬季的脓毒症数量与儿科 H&N 脓毒症的预期发病率相符。
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引用次数: 0
Dysphagia is a strong predictor of revision supraglottoplasty in pediatric laryngomalacia 吞咽困难是预测小儿喉头畸形喉上成形术翻修的一个重要因素
IF 1.2 4区 医学 Q3 OTORHINOLARYNGOLOGY Pub Date : 2024-09-17 DOI: 10.1016/j.ijporl.2024.112115
Amy Callaghan , Hamdy El-Hakim , Amanda R. Adsett , Daniela M. Isaac , Andre Isaac

Background

There is growing research on the association between swallowing dysfunction and laryngomalacia. Supraglottoplasty is the surgical intervention used to treat laryngomalacia, however a portion of patients who undergo this procedure will require a revision surgery. Predictive risk factors for revision supraglottoplasty in patients with laryngomalacia are not well understood, and previous studies failed to evaluate swallowing systematically.

Hypothesis

We predict a significant association between swallowing dysfunction and revision supraglottoplasty for patients with laryngomalacia.

Methods

This was a retrospective cohort study of consecutive patients between 2013 and 2023 at a tertiary pediatric care centre (Stollery Children's Hospital). All patients had an endoscopic diagnosis of laryngomalacia by a staff otolaryngologist and at minimum a systematic clinical swallowing assessment by a speech language pathologist, with an instrumental assessment as needed. Patients with genetic or neurological comorbidities, lack of follow up information, or age of >3 years were excluded. Clinical and instrumental swallow data, demographic information, surgical outcomes and revision surgeries were documented and collected. Univariate analysis was done to determine associations between variables and revision supraglottoplasty. Binary logistic regression was done to determine independent predictors of revision supraglottoplasty.

Results

214 patients met the inclusion criteria and were analyzed in the study. 24 patients (11 %) required revision supraglottoplasty. 118 out of the 214 patients (55 %) had an instrumental assessment completed (FEES or VFSS). Of those, 92 (78 %) had abnormal findings on instrumental assessments. Univariate analysis showed Type 2 laryngomalacia (P = 0.017), presence of aspiration (P=<0.001), presence of cyanosis (P = 0.002) and abnormal findings on an instrumental assessment (P = 0.013) to be significantly associated with the need for revision supraglottoplasty. Binary regression analysis showed aspiration (OR = 5.6 {2.087–14.889}, P=<0.001) and cyanosis (OR = 5.3 {1.852–15.181}, P = 0.002) to be the only independent predictors of revision supraglottoplasty.

Conclusion

Presence of aspiration is a strong predictive factor for revision supraglottoplasty in patients with laryngomalacia, when swallowing is evaluated systematically. More prospective research is needed to understand the relationship between swallowing dysfunction, laryngomalacia and surgery.

背景关于吞咽功能障碍与喉水肿之间关系的研究越来越多。声门上成形术是用于治疗喉肌无力的手术干预措施,但部分接受过该手术的患者需要进行翻修手术。我们预测吞咽功能障碍与喉上成形术翻修之间存在显著关联。方法这是一项回顾性队列研究,研究对象为一家三级儿科医疗中心(斯托莱里儿童医院)2013年至2023年间的连续患者。所有患者均经耳鼻喉科医生内镜诊断为喉发育不全,并至少由言语病理学家进行了系统的临床吞咽评估,必要时还进行了仪器评估。有遗传或神经系统合并症、缺乏随访信息或年龄小于 3 岁的患者被排除在外。记录并收集了临床和仪器吞咽数据、人口统计学信息、手术结果和翻修手术。通过单变量分析确定变量与翻修声门上成形术之间的关联。结果214名患者符合纳入标准,并在研究中进行了分析。24名患者(11%)需要进行翻修声门上成形术。214 名患者中有 118 名(55%)完成了仪器评估(FEES 或 VFSS)。其中 92 人(78%)的器械评估结果异常。单变量分析显示,2 型喉瘤(P = 0.017)、吸入(P=0.001)、发绀(P = 0.002)和器械评估结果异常(P = 0.013)与翻修声门上成形术的需求显著相关。二元回归分析显示,吸入(OR = 5.6 {2.087-14.889}, P=<0.001)和发绀(OR = 5.3 {1.852-15.181}, P=0.002)是唯一可预测喉上成形术翻修的独立因素。需要进行更多的前瞻性研究,以了解吞咽功能障碍、喉气肿和手术之间的关系。
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引用次数: 0
期刊
International journal of pediatric otorhinolaryngology
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