首页 > 最新文献

Environment & Health最新文献

英文 中文
Long-term dynamics of resistance to occupational burnout in pedagogical staff of different types of educational institutions 不同类型教育机构教师职业倦怠抵抗的长期动态
Pub Date : 2022-09-01 DOI: 10.32402/dovkil2022.03.029
© Калиниченко, Латіна Г.О Стаття
Objective: The aim of the study was to assess the level of professional burnout among teachers of educational institutions of various types in the long-term dynamics, taking into account the forms of work organization. Materials and methods: During 2008 - 2021 the level of occupational burnout was monitored in 852 pedagogical workers of the Sumy region. The study was carried out according to the method of V. V. Boyko «Diagnostics of the level of occupational burnout». The study included three stages. In 2008, 420 teachers of secondary education institutions were surveyed. In 2020, 342 teachers of preschool and primary schools were examined. In 2021, 85 teachers of secondary education institutions were examined. In 2021, the organization of the educational process was taken into account. It included an online format in the context of the COVID-19 pandemic caused by the SARS-CoV-2 coronavirus, taking into account a history of coronavirus disease. Results: During the entire observation period, a low level of occupational burnout prevailed among teaching staff. Over the years, there has been a steady trend in the spread of the average level of occupational burnout, which has a negative sign of a protracted course with regular symptoms. The dependence of the development of the general syndrome of occupational burnout on age was established (r=-0,87, p<0,01). In 2008, occupational burnout was formed at the expense of teachers aged 31-40 years old. In recent years of observation, all levels of occupational burnout were formed at the expense of teachers aged 51 years old and more. Thus, the teachers retained the features of the psycho-emotional state with manifestations of occupational burnout after twelve years of observation and formed groups with high occupational burnout at the time of the re-examination. As of February 2021, 63,53% of teaching staff in the observation group had a history of coronavirus disease. Regardless of this, there was a general tendency among pedagogical workers for the advantage of low and medium levels of occupational burnout over high. A high level of professional burnout among teachers who underwent COVID-19 (9,26±0,95 %) was recorded in 3,64%, which is less than the same group of teachers (with a high level of professional burnout) without a history of COVID-19 (12,90±1,34 %, t=2,21, p<0,05). It has been established that the development of professional burnout is not associated with the psycho-emotional state of the coronavirus disease, since the main factors in the formation of professional burnout are the organizational factors of the labor process. Conclusions: During 2008-2021, teachers experienced an increase in the rate of development of occupational burnout. The dependence of occupational burnout on age has been established.
目的:在考虑工作组织形式的情况下,对不同类型教育机构教师的职业倦怠水平进行长期动态评估。材料和方法:在2008 - 2021年期间,对苏梅地区852名教学工作者的职业倦怠水平进行了监测。本研究依据v.v. Boyko«职业倦怠水平诊断»的方法进行。研究分为三个阶段。2008年,对420名中等教育机构教师进行了调查。2020年,共对342名幼儿园和小学教师进行了检查。2021年,85名中等教育机构的教师接受了考试。2021年,考虑到教育过程的组织。它包括了在SARS-CoV-2冠状病毒引起的COVID-19大流行背景下的在线格式,同时考虑到冠状病毒疾病的历史。结果:在整个观察期内,教师职业倦怠水平较低。多年来,职业倦怠的平均水平有稳定的蔓延趋势,这是一个长期的负面迹象,有规律的症状。职业倦怠一般综合征的发生与年龄存在相关性(r=-0,87, p< 0.01)。2008年,职业倦怠以31-40岁的教师为代价形成。近年来的观察发现,各级职业倦怠都是以51岁及以上的教师为代价形成的。因此,经过12年的观察,教师在复试时保持了职业倦怠表现的心理情绪状态特征,形成了高职业倦怠的群体。截至2021年2月,观察组63.53%的教学人员有冠状病毒病史。尽管如此,在教育工作者中有一个普遍的趋势,即低和中等水平的职业倦怠比高水平的职业倦怠更有优势。经历过新冠肺炎的教师职业倦怠程度高(9.26±0.95%)的比例为3.64%,低于未经历过新冠肺炎的同组教师(12.90±1.34%,t=2,21, p< 0.05)。已经确定职业倦怠的发展与冠状病毒病的心理情绪状态无关,因为职业倦怠形成的主要因素是劳动过程的组织因素。结论:2008-2021年,教师职业倦怠的发展速度呈上升趋势。职业倦怠对年龄的依赖关系已经确立。
{"title":"Long-term dynamics of resistance to occupational burnout in pedagogical staff of different types of educational institutions","authors":"© Калиниченко, Латіна Г.О Стаття","doi":"10.32402/dovkil2022.03.029","DOIUrl":"https://doi.org/10.32402/dovkil2022.03.029","url":null,"abstract":"Objective: The aim of the study was to assess the level of professional burnout among teachers of educational institutions of various types in the long-term dynamics, taking into account the forms of work organization. Materials and methods: During 2008 - 2021 the level of occupational burnout was monitored in 852 pedagogical workers of the Sumy region. The study was carried out according to the method of V. V. Boyko «Diagnostics of the level of occupational burnout». The study included three stages. In 2008, 420 teachers of secondary education institutions were surveyed. In 2020, 342 teachers of preschool and primary schools were examined. In 2021, 85 teachers of secondary education institutions were examined. In 2021, the organization of the educational process was taken into account. It included an online format in the context of the COVID-19 pandemic caused by the SARS-CoV-2 coronavirus, taking into account a history of coronavirus disease. Results: During the entire observation period, a low level of occupational burnout prevailed among teaching staff. Over the years, there has been a steady trend in the spread of the average level of occupational burnout, which has a negative sign of a protracted course with regular symptoms. The dependence of the development of the general syndrome of occupational burnout on age was established (r=-0,87, p<0,01). In 2008, occupational burnout was formed at the expense of teachers aged 31-40 years old. In recent years of observation, all levels of occupational burnout were formed at the expense of teachers aged 51 years old and more. Thus, the teachers retained the features of the psycho-emotional state with manifestations of occupational burnout after twelve years of observation and formed groups with high occupational burnout at the time of the re-examination. As of February 2021, 63,53% of teaching staff in the observation group had a history of coronavirus disease. Regardless of this, there was a general tendency among pedagogical workers for the advantage of low and medium levels of occupational burnout over high. A high level of professional burnout among teachers who underwent COVID-19 (9,26±0,95 %) was recorded in 3,64%, which is less than the same group of teachers (with a high level of professional burnout) without a history of COVID-19 (12,90±1,34 %, t=2,21, p<0,05). It has been established that the development of professional burnout is not associated with the psycho-emotional state of the coronavirus disease, since the main factors in the formation of professional burnout are the organizational factors of the labor process. Conclusions: During 2008-2021, teachers experienced an increase in the rate of development of occupational burnout. The dependence of occupational burnout on age has been established.","PeriodicalId":144023,"journal":{"name":"Environment &amp; Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125354689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determination of polyphenol compounds in medicinal plants of local habitat and their importance for health 地方药用植物中多酚类化合物的测定及其健康意义
Pub Date : 2022-09-01 DOI: 10.32402/dovkil2022.03.057
O. Pylypenko, L. Sukhovirska, N. Operchuk
Objective: Assess the possibility of using some medicinal plants containing polyphenolic compounds (tannins and gallic acid) in medicine. Materials and methods: The Folin-Ciocalteu reagent spectrophotometry method is used to determine the amount of polyphenolic compounds. The gallic acid solution was selected as the standard sample. The objects of the study were dry specimens of plants: Oak Bark (quercus cortex), Rhizomes of Bistorta officinalis (bistortae rhizomata), Galls of Oak leaves (gallae turcicae), Rhizomes of Potentilla erecta (tormentillae rhizomata). Experimental samples in the form of aqueous and alcoholic extracts are made from this dry raw material. Results: Studies have shown that all selected plants have sufficient tannin content to confirm their healing properties. The largest number was found in the galls of oak leaves. Alcohol extracts extracted polyphenolic compounds from plant raw materials better than aqueous ones, but the difference is relatively small. Therefore, aqueous extracts can be used as therapeutic drugs for those who are contraindicated alcohol extracts. Conclusions: The studied dry specimens of plants (oak bark (quercus cortex), rhizomes of snake mustard (bistortae rhizomata), galls of oak leaves (gallae turcicae), rhizomes of erect cinquefoil (tormentillae rhizomata)) contain polyphenolic compounds (tannin and gallic acid) in sufficient quantities to provide medicinal effect. It has been shown that the extraction of polyphenolic compounds from plant materials using alcohol solutions is more efficient than aqueous extracts. It is recommended to use herbal products with tannins in medicinal practice.
目的:评价含多酚类化合物(单宁、没食子酸)的药用植物在医药中的应用可能性。材料和方法:采用Folin-Ciocalteu试剂分光光度法测定多酚类化合物的含量。以没食子酸溶液为标准品。研究对象为干燥的植物标本:栎皮(栎皮)、白栎根茎(白栎根茎)、栎叶瘿(白栎瘿)、直陵草根茎(白栎根茎)。实验样品在水和酒精提取物的形式是由这种干燥的原料。结果:研究表明,所有选定的植物都有足够的单宁含量,以证实其愈合性能。在橡树叶的瘿中发现的数量最多。醇提液对植物原料中多酚类化合物的提取效果优于水提液,但差异较小。因此,水提取物可作为治疗药物用于那些禁忌酒精提取物。结论:所研究的植物干标本(栎皮)、蛇芥根茎、栎叶胆、金银花根茎)均含有足够量的多酚类化合物(单宁和没食子酸),具有一定的药用价值。研究表明,从植物原料中提取多酚类化合物,采用乙醇溶液比水萃取更有效。建议在医学实践中使用含有单宁的草药产品。
{"title":"Determination of polyphenol compounds in medicinal plants of local habitat and their importance for health","authors":"O. Pylypenko, L. Sukhovirska, N. Operchuk","doi":"10.32402/dovkil2022.03.057","DOIUrl":"https://doi.org/10.32402/dovkil2022.03.057","url":null,"abstract":"Objective: Assess the possibility of using some medicinal plants containing polyphenolic compounds (tannins and gallic acid) in medicine. Materials and methods: The Folin-Ciocalteu reagent spectrophotometry method is used to determine the amount of polyphenolic compounds. The gallic acid solution was selected as the standard sample. The objects of the study were dry specimens of plants: Oak Bark (quercus cortex), Rhizomes of Bistorta officinalis (bistortae rhizomata), Galls of Oak leaves (gallae turcicae), Rhizomes of Potentilla erecta (tormentillae rhizomata). Experimental samples in the form of aqueous and alcoholic extracts are made from this dry raw material. Results: Studies have shown that all selected plants have sufficient tannin content to confirm their healing properties. The largest number was found in the galls of oak leaves. Alcohol extracts extracted polyphenolic compounds from plant raw materials better than aqueous ones, but the difference is relatively small. Therefore, aqueous extracts can be used as therapeutic drugs for those who are contraindicated alcohol extracts. Conclusions: The studied dry specimens of plants (oak bark (quercus cortex), rhizomes of snake mustard (bistortae rhizomata), galls of oak leaves (gallae turcicae), rhizomes of erect cinquefoil (tormentillae rhizomata)) contain polyphenolic compounds (tannin and gallic acid) in sufficient quantities to provide medicinal effect. It has been shown that the extraction of polyphenolic compounds from plant materials using alcohol solutions is more efficient than aqueous extracts. It is recommended to use herbal products with tannins in medicinal practice.","PeriodicalId":144023,"journal":{"name":"Environment &amp; Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122625035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The difference of the concept of "malady" in the context of public health: (part 1 - analytical research) 公共卫生背景下"疾病"概念的差异:(第一部分——分析性研究)
Pub Date : 2022-09-01 DOI: 10.32402/dovkil2022.03.004
O. Berdnyk, T. Skochko, O. Dobrianska, О. Rudnytska
Target. From the standpoint of public health, analyze scientific literature data and terminology related to various hypostases / manifestations of malady. Materials and methods. The analysis of domestic and foreign publications devoted to terminological issues of assessing various aspects of the incidence of the population. Results. The state of research concerning various aspects of the concept of "disorder" in the scientific domestic and foreign literature has been determined. A review of the scientific literature revealed a lack of theoretical provisions on this topic that could be generalized, compared and contrasted. In everyday English, the use of concepts to describe malady (disease, illness, sickness, etc.) is often seen as arbitrary, and in the scientific field, they are the subject of professional discussions. For Ukraine, the analysis of malady terminology is new. The designation of the space for the use of certain terms is important, since the study of various aspects of the malady involves the use of various methods of collecting information, interpreting the data obtained, conclusions about ways to overcome disorders, etc. The definition of malady is not only a theoretical issue: it is important for medicine, social policy and the health care system in general. For public health, which is the most socially oriented branch of medicine, it is extremely important to take into account not only the purely biomedical (disease), but also the social (sickness) aspects of the disorders, as well as its self-esteem (illness).The combination and interrelation of various hypostases of the disorders included in the Twaddle triad is considered, a comparative analysis of its components has been carried out. The relevance of the analysis of the morbidity of the population and the justification of the most effective health-improving measures determines the advisability of taking into account various hypostases of ill health, and given the multidisciplinary nature of public health, the involvement of specialists in various fields.
目标。从公共卫生的角度,分析与疾病的各种实质/表现有关的科学文献数据和术语。材料和方法。分析国内和国外的出版物,专门讨论评估人口发病率的各个方面的术语问题。结果。国内外科学文献中关于“障碍”概念的各个方面的研究状况已经确定。通过对科学文献的回顾发现,关于这一主题缺乏可以概括、比较和对比的理论规定。在日常英语中,使用概念来描述疾病(疾病,疾病,疾病等)通常被认为是武断的,在科学领域,它们是专业讨论的主题。对乌克兰来说,对疾病术语的分析是新的。指定使用某些术语的空间是很重要的,因为对这种疾病的各个方面的研究涉及使用各种收集信息的方法、解释所获得的数据、关于克服疾病的方法的结论等。疾病的定义不仅是一个理论问题:它对医学、社会政策和一般的卫生保健系统都很重要。公共卫生是最面向社会的医学分支,因此极为重要的是,不仅要考虑到纯粹的生物医学(疾病),而且要考虑到疾病的社会(疾病)方面及其自尊(疾病)。考虑了Twaddle三位一体中包括的各种疾病的组合和相互关系,并对其组成部分进行了比较分析。人口发病率分析的相关性和最有效的改善健康措施的合理性决定了考虑到各种健康状况不佳的本质是明智的,并且鉴于公共卫生的多学科性质,需要各领域专家的参与。
{"title":"The difference of the concept of \"malady\" in the context of public health: (part 1 - analytical research)","authors":"O. Berdnyk, T. Skochko, O. Dobrianska, О. Rudnytska","doi":"10.32402/dovkil2022.03.004","DOIUrl":"https://doi.org/10.32402/dovkil2022.03.004","url":null,"abstract":"Target. From the standpoint of public health, analyze scientific literature data and terminology related to various hypostases / manifestations of malady. Materials and methods. The analysis of domestic and foreign publications devoted to terminological issues of assessing various aspects of the incidence of the population. Results. The state of research concerning various aspects of the concept of \"disorder\" in the scientific domestic and foreign literature has been determined. A review of the scientific literature revealed a lack of theoretical provisions on this topic that could be generalized, compared and contrasted. In everyday English, the use of concepts to describe malady (disease, illness, sickness, etc.) is often seen as arbitrary, and in the scientific field, they are the subject of professional discussions. For Ukraine, the analysis of malady terminology is new. The designation of the space for the use of certain terms is important, since the study of various aspects of the malady involves the use of various methods of collecting information, interpreting the data obtained, conclusions about ways to overcome disorders, etc. The definition of malady is not only a theoretical issue: it is important for medicine, social policy and the health care system in general. For public health, which is the most socially oriented branch of medicine, it is extremely important to take into account not only the purely biomedical (disease), but also the social (sickness) aspects of the disorders, as well as its self-esteem (illness).The combination and interrelation of various hypostases of the disorders included in the Twaddle triad is considered, a comparative analysis of its components has been carried out. The relevance of the analysis of the morbidity of the population and the justification of the most effective health-improving measures determines the advisability of taking into account various hypostases of ill health, and given the multidisciplinary nature of public health, the involvement of specialists in various fields.","PeriodicalId":144023,"journal":{"name":"Environment &amp; Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123059936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Scientific substantiation of standards of health physical activity for primary-school-age children 科学证实小学学龄儿童健康体育活动标准
Pub Date : 2022-09-01 DOI: 10.32402/dovkil2022.03.037
S. Hozak, O. Yelizarova, I. A. Kalinichenko, T.V. Stankevych, A. Parats
The aim of the study was to determine the optimal volume of primary-school-age children's physical activity to improve their adaptive capabilities. Materials and methods. The features of physical activity, social factors, anthropometric, and physiological parameters of 297 students in grades 1-4 of schools in Sumy were studied using diaries that parents filled out during the week and examination by a paediatrician (2016). The duration of moderate-to-vigorous physical activity (MVPA) was determined. The adaptive-reserve capabilities (ARV) integral indicator was calculated. ARV due to the characteristics of physical development, and the functioning of the autonomic nervous and cardiovascular systems of the child. Descriptive statistics, contingency tables, dispersion, correlation analysis, and linear regression models were used. Results. We have established that the proportion of children with an unsatisfactory level of adaptive-reserve capabilities among primary-school-age children was about 40%. A trend towards a decrease in ARV in children with chronic diseases was revealed. A relationship between ARV and the duration of sports activities was established (p<0.01). The total value of MVPA was 215.2±16.6 min/week for boys and 189.0±14.0 min/week for girls (p>0.2). The weekly duration of MVPA in children who play organized sports is higher than in those who do it on their own (p<0.001). Estimated health-saving values of MVPA are from 43 to 68 minutes/day with an average value of 55 minutes for boys and from 37 to 61 minutes/day with an average value of 50 minutes for girls. Non-compliance with these norms can lead to a decrease in ARV, especially in the group of children with chronic diseases. Conclusions: The average duration of daily MVPA (with energy consumption of more than 3 METs) should be 55 minutes for boys and 50 minutes for girls for increasing the adaptive-reserve capabilities of children in the age group of 6-10 years.
该研究的目的是确定小学适龄儿童体育活动的最佳量,以提高他们的适应能力。材料和方法。采用家长在一周内填写的日记和儿科医生的检查,研究了苏梅市297名1-4年级学生的身体活动特征、社会因素、人体测量和生理参数(2016)。测定中度至剧烈体力活动(MVPA)持续时间。计算了自适应储备能力(ARV)积分指标。由于儿童身体发育的特点,以及自主神经和心血管系统的功能。采用描述性统计、列联表、离散、相关分析和线性回归模型。结果。我们已经确定,在小学适龄儿童中,适应储备能力水平不令人满意的儿童比例约为40%。慢性病儿童的抗逆转录病毒治疗呈下降趋势。ARV与体育活动持续时间之间存在关系(p0.2)。参加有组织运动的儿童每周MVPA持续时间高于自行运动的儿童(p<0.001)。估计MVPA的保健价值为每天43至68分钟,男孩的平均值为55分钟,女孩的平均值为每天37至61分钟,女孩的平均值为50分钟。不遵守这些规范可能导致抗逆转录病毒药物的减少,特别是在患有慢性病的儿童群体中。结论:为了提高6-10岁儿童的适应储备能力,男孩每日MVPA(能量消耗大于3mets)的平均持续时间应为55分钟,女孩为50分钟。
{"title":"Scientific substantiation of standards of health physical activity for primary-school-age children","authors":"S. Hozak, O. Yelizarova, I. A. Kalinichenko, T.V. Stankevych, A. Parats","doi":"10.32402/dovkil2022.03.037","DOIUrl":"https://doi.org/10.32402/dovkil2022.03.037","url":null,"abstract":"The aim of the study was to determine the optimal volume of primary-school-age children's physical activity to improve their adaptive capabilities. Materials and methods. The features of physical activity, social factors, anthropometric, and physiological parameters of 297 students in grades 1-4 of schools in Sumy were studied using diaries that parents filled out during the week and examination by a paediatrician (2016). The duration of moderate-to-vigorous physical activity (MVPA) was determined. The adaptive-reserve capabilities (ARV) integral indicator was calculated. ARV due to the characteristics of physical development, and the functioning of the autonomic nervous and cardiovascular systems of the child. Descriptive statistics, contingency tables, dispersion, correlation analysis, and linear regression models were used. Results. We have established that the proportion of children with an unsatisfactory level of adaptive-reserve capabilities among primary-school-age children was about 40%. A trend towards a decrease in ARV in children with chronic diseases was revealed. A relationship between ARV and the duration of sports activities was established (p<0.01). The total value of MVPA was 215.2±16.6 min/week for boys and 189.0±14.0 min/week for girls (p>0.2). The weekly duration of MVPA in children who play organized sports is higher than in those who do it on their own (p<0.001). Estimated health-saving values of MVPA are from 43 to 68 minutes/day with an average value of 55 minutes for boys and from 37 to 61 minutes/day with an average value of 50 minutes for girls. Non-compliance with these norms can lead to a decrease in ARV, especially in the group of children with chronic diseases. Conclusions: The average duration of daily MVPA (with energy consumption of more than 3 METs) should be 55 minutes for boys and 50 minutes for girls for increasing the adaptive-reserve capabilities of children in the age group of 6-10 years.","PeriodicalId":144023,"journal":{"name":"Environment &amp; Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124668065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Assessment of the potential toxicity of detergents with disinfectants properties on cell culture in vitro 具有消毒剂特性的洗涤剂对体外细胞培养的潜在毒性评价
Pub Date : 2022-06-01 DOI: 10.32402/dovkil2022.02.004
N. Dmytrukha, T. K. Korolenko, O. Lahutina, L. A. Lehkostup
Detergents with disinfectants properties today are widely used in various fields of human activity for cleaning surfaces, equipment, tools while destroying infectious agents. An active substance, as disinfectants, it contains various chemical compounds with antimicrobial, antiviral and antifungal properties. To establish the safety of these substances, along with toxicological studies on animals, experiments are conducted on alternative in vitro test systems, in particular on cell culture, which allows to quickly assess and predict the potential toxicity of detergents to humans and other living organisms. The purpouse of the study was assessment of the potential danger of detergents and disinfectants for humans by determining their cytotoxic effects in experiments on cell culture in vitro. Material and methods. Studies were performed to evaluate the cytotoxic effect of detergents with disinfectants properties : "Bioblysk", "Blysk Plus" and "Blysk" (manufactured by PE "HYGIENICS", Poland) on the lung cancer cells (line A-549) using cytochemical methods: MTT- with methyltetrazolium blue and CRB - test with sulforodamine B. Results. It was found that all detergents have the greatest cytotoxic effect on A-549 cells at a concentration of 1.0% of the native solution. The lowest concentrations 0.03% and 0.015% have no toxic effect on cells. With the help of probit analysis based on the obtained results, LC50 values were calculated: for Bioblysk - 0.15% (MTT test) and 0.15% (CRP test); for Blysk Plus LC50 - 0.25% (MTT test) and 0.2% (CRP test); for Blysk - 0.2% (MTT test and CRP test). LC50 values for detergents were 10 times lower than the recommended minimum concentrations of working solutions Conclusions. The obtained data indicate that the citotoxicity effect of detergents on A-549 cells was manifested by the effect on mitochondrial function and protein synthesis. The severity of studied drugs toxic effect depended on its chemical composition and pH, concentration in the incubation medium. The calculated LC50 values indicate their possible danger to the respiratory system, so they require appropriate protection.
如今,具有消毒剂特性的洗涤剂被广泛应用于人类活动的各个领域,用于清洁表面、设备、工具,同时破坏传染性病原体。作为消毒剂的一种活性物质,它含有各种具有抗菌、抗病毒和抗真菌特性的化合物。为了确定这些物质的安全性,以及对动物进行毒理学研究,在替代的体外测试系统上进行了实验,特别是在细胞培养上,这可以快速评估和预测洗涤剂对人类和其他生物的潜在毒性。本研究的目的是在体外细胞培养实验中,通过确定洗涤剂和消毒剂的细胞毒性作用,评估它们对人类的潜在危险。材料和方法。采用细胞化学方法对具有消毒剂特性的清洁剂进行了研究:"Bioblysk"、"Blysk Plus"和"Blysk"(波兰PE "HYGIENICS"生产)对肺癌细胞(A-549系)的细胞毒作用进行了评估:甲基四氮唑蓝MTT试验和磺胺乙胺b CRB试验。结果表明,在天然溶液浓度为1.0%时,所有洗涤剂对a -549细胞的细胞毒作用最大。最低浓度0.03%和0.015%对细胞无毒性作用。根据所得结果进行probit分析,计算LC50值:biblysk - 0.15% (MTT试验)和0.15% (CRP试验);Blysk Plus LC50 - 0.25% (MTT试验)和0.2% (CRP试验);Blysk - 0.2% (MTT试验和CRP试验)。洗涤剂的LC50值比推荐的最低工作溶液浓度低10倍。结果表明,洗涤剂对A-549细胞的毒性作用主要表现在对线粒体功能和蛋白质合成的影响上。所研究药物的毒性作用的严重程度取决于其化学成分和培养液的pH、浓度。计算出的LC50值表明它们可能对呼吸系统有危险,因此需要适当的保护。
{"title":"Assessment of the potential toxicity of detergents with disinfectants properties on cell culture in vitro","authors":"N. Dmytrukha, T. K. Korolenko, O. Lahutina, L. A. Lehkostup","doi":"10.32402/dovkil2022.02.004","DOIUrl":"https://doi.org/10.32402/dovkil2022.02.004","url":null,"abstract":"Detergents with disinfectants properties today are widely used in various fields of human activity for cleaning surfaces, equipment, tools while destroying infectious agents. An active substance, as disinfectants, it contains various chemical compounds with antimicrobial, antiviral and antifungal properties. To establish the safety of these substances, along with toxicological studies on animals, experiments are conducted on alternative in vitro test systems, in particular on cell culture, which allows to quickly assess and predict the potential toxicity of detergents to humans and other living organisms. The purpouse of the study was assessment of the potential danger of detergents and disinfectants for humans by determining their cytotoxic effects in experiments on cell culture in vitro. Material and methods. Studies were performed to evaluate the cytotoxic effect of detergents with disinfectants properties : \"Bioblysk\", \"Blysk Plus\" and \"Blysk\" (manufactured by PE \"HYGIENICS\", Poland) on the lung cancer cells (line A-549) using cytochemical methods: MTT- with methyltetrazolium blue and CRB - test with sulforodamine B. Results. It was found that all detergents have the greatest cytotoxic effect on A-549 cells at a concentration of 1.0% of the native solution. The lowest concentrations 0.03% and 0.015% have no toxic effect on cells. With the help of probit analysis based on the obtained results, LC50 values were calculated: for Bioblysk - 0.15% (MTT test) and 0.15% (CRP test); for Blysk Plus LC50 - 0.25% (MTT test) and 0.2% (CRP test); for Blysk - 0.2% (MTT test and CRP test). LC50 values for detergents were 10 times lower than the recommended minimum concentrations of working solutions Conclusions. The obtained data indicate that the citotoxicity effect of detergents on A-549 cells was manifested by the effect on mitochondrial function and protein synthesis. The severity of studied drugs toxic effect depended on its chemical composition and pH, concentration in the incubation medium. The calculated LC50 values indicate their possible danger to the respiratory system, so they require appropriate protection.","PeriodicalId":144023,"journal":{"name":"Environment &amp; Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121586578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetic control of homocysteine metabolism in children living near the chоrnobyl exclusion zone 居住在切尔诺贝利隔离区附近儿童同型半胱氨酸代谢的遗传控制
Pub Date : 2022-06-01 DOI: 10.32402/dovkil2022.02.010
Yu.I. Bandazhevskyi, N. Dubova
The aim of study: to determine the involvement of folate cycle genes in the occurrence of hyperhomocysteinemia in children from Ivankivskyi district of Kyiv region of Ukraine 35 years after the accident at the Chornobyl nuclear power plant. Research methods. Immunochemical, mathematical and statistical. Results. Homocysteine levels were determined in 217 children aged 12-17 from Ivankivskyi district of Kyiv region, as well as genetic polymorphisms of the folate cycle. An excess of homocysteine in the blood over 10 µmol/l (a state of hyperhomocysteinemia) was detected in 65.44 % (142 out of 217) of those examined, among boys – 69.79 % (67 out of 96), among girls – 61.98 % (75 out of 121). The largest proportion of hyperhomocysteinemia cases was registered in the subgroup of children with the basic polymorphism MTHFR: 677TT – 94.44 % of cases. In most cases, hyperhomocysteinemia in children was associated with an environmental factor, including radioactive elements and their decay products. The system for the prevention of hyperhomocysteinemia and its consequences in children living in areas affected by the accident at the Chornobyl nuclear power plant should include regular monitoring of the content of radionuclides in the body of children and locally produced food, the content of homocysteine in the blood, and assessment of the state of folate cycle genes.
研究目的:在切尔诺贝利核电站事故发生35年后,确定叶酸周期基因与乌克兰基辅地区Ivankivskyi地区儿童高同型半胱氨酸血症发生的关系。研究方法。免疫化学,数学和统计。结果。测定了基辅地区Ivankivskyi区的217名12-17岁儿童的同型半胱氨酸水平,以及叶酸循环的遗传多态性。在接受检查的人中,65.44%(217人中有142人)检测到血液中同型半胱氨酸过量超过10 μ mol/l(高同型半胱氨酸血症状态),在男孩中为69.79%(96人中有67人),在女孩中为61.98%(121人中有75人)。高同型半胱氨酸血症病例在基本多态性MTHFR的儿童亚组中所占比例最大:677TT,占94.44%。在大多数情况下,儿童高同型半胱氨酸血症与环境因素有关,包括放射性元素及其衰变产物。预防生活在切尔诺贝利核电站事故影响地区的儿童高同型半胱氨酸血症及其后果的系统应包括定期监测儿童体内和当地生产的食物中的放射性核素含量、血液中同型半胱氨酸的含量以及评估叶酸循环基因的状况。
{"title":"Genetic control of homocysteine metabolism in children living near the chоrnobyl exclusion zone","authors":"Yu.I. Bandazhevskyi, N. Dubova","doi":"10.32402/dovkil2022.02.010","DOIUrl":"https://doi.org/10.32402/dovkil2022.02.010","url":null,"abstract":"The aim of study: to determine the involvement of folate cycle genes in the occurrence of hyperhomocysteinemia in children from Ivankivskyi district of Kyiv region of Ukraine 35 years after the accident at the Chornobyl nuclear power plant. Research methods. Immunochemical, mathematical and statistical. Results. Homocysteine levels were determined in 217 children aged 12-17 from Ivankivskyi district of Kyiv region, as well as genetic polymorphisms of the folate cycle. An excess of homocysteine in the blood over 10 µmol/l (a state of hyperhomocysteinemia) was detected in 65.44 % (142 out of 217) of those examined, among boys – 69.79 % (67 out of 96), among girls – 61.98 % (75 out of 121). The largest proportion of hyperhomocysteinemia cases was registered in the subgroup of children with the basic polymorphism MTHFR: 677TT – 94.44 % of cases. In most cases, hyperhomocysteinemia in children was associated with an environmental factor, including radioactive elements and their decay products. The system for the prevention of hyperhomocysteinemia and its consequences in children living in areas affected by the accident at the Chornobyl nuclear power plant should include regular monitoring of the content of radionuclides in the body of children and locally produced food, the content of homocysteine in the blood, and assessment of the state of folate cycle genes.","PeriodicalId":144023,"journal":{"name":"Environment &amp; Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123539757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cancer incidence in the population of Ukraine in remote period after the Chornobyl accident 切尔诺贝利事故后遥远时期乌克兰人口癌症发病率
Pub Date : 2022-06-01 DOI: 10.32402/dovkil2022.02.016
A.Ye. Prysyazhniuk, D. Bazyka, N.A. Hudzenko, M. Fuzik, N. Trotsiuk, N. Babkina, O. Khukhrianska, S. A. Danevych
There is performed a study of cancer incidence in the population affected by the Chornobyl accident. Analysis of demography situation has shown that unlike Western European countries with increasing life expectancy this index was notably decreased in Ukraine in 2005–2006 with slow growth during 2006–2019. Certainly this circumstance may influence on cancer incidence rate because the highest risk of malignant tumours is just in elderly age. Goal: to determine the frequency and risk of malignant neoplasms in groups of the population of Ukraine that were exposed to radiation as a result of the Chоrnobyl accident in the remote post-accident period. Materials and methods. The study was conducted on the basis of long-term monitoring of malignant tumours in the groups of victims – clean-up workers of 1986–1987, evacuees from the exclusion zone, residents of the territories most heavily contaminated with radionuclides. Results. There was a significant excess of the expected level of incidence of thyroid cancer among the participants in liquidation of the accident consequences (PLAC) - 4.5 times, evacuees - 3.8 times, residents of territories contaminated with radionuclides - 1.3 times. Leukaemia and lymphoma incidence rate in residents of contaminated territories increased sharply in the first years after the accident but decreased in the next years and not exceeded the level if Kyiv and Zhytomyr regions and Ukraine at whole. In a joint Ukrainian-American analytical epidemiological case-control study dose dependent excess relative risk of leukaemia (ERR/Gy) was proved in clean-up workers and defined at level 2.38 (0.49–5.87) in 1986–2006. A significant excess of the national level of incidence of breast cancer was determined only in women - PLAC in 1986–1987. In 1994–2019 SIR was 156.3% (95% CI: 141.0–171.5). Conclusions. Because latency period for different forms of radiation related malignancies might be very long further special attention should be paid not only to nosological forms mentioned above but also to cancers of the other sites.
对受切尔诺贝利事故影响的人群的癌症发病率进行了研究。对人口状况的分析表明,与预期寿命增加的西欧国家不同,乌克兰的预期寿命指数在2005-2006年显著下降,2006-2019年增长缓慢。当然,这种情况可能会影响癌症的发病率,因为恶性肿瘤的最高风险正是在老年人。目标:确定乌克兰因切尔诺贝利事故而暴露于辐射的人群在事故后遥远时期发生恶性肿瘤的频率和风险。材料和方法。这项研究是在长期监测受害者群体恶性肿瘤的基础上进行的- - 1986-1987年的清理工人、从隔离区撤离的人、受放射性核素污染最严重的领土的居民。结果。在清理事故后果(placc)的参与者中,甲状腺癌的发病率明显超过预期水平——4.5倍,撤离者——3.8倍,受放射性核素污染地区的居民——1.3倍。在事故发生后的头几年,受污染地区居民的白血病和淋巴瘤发病率急剧上升,但在接下来的几年中下降,不超过基辅和日托米尔地区以及整个乌克兰的水平。在一项乌克兰-美国联合分析流行病学病例对照研究中,1986-2006年在清理工人中证实了剂量依赖的白血病过度相对危险度(ERR/Gy),并确定为2.38(0.49-5.87)水平。1986-1987年,只有女性乳腺癌发病率明显高于全国水平。1994-2019年,SIR为156.3% (95% CI: 141.0-171.5)。结论。由于不同形式的放射相关恶性肿瘤的潜伏期可能很长,因此不仅应特别注意上述的疾病形式,还应注意其他部位的癌症。
{"title":"Cancer incidence in the population of Ukraine in remote period after the Chornobyl accident","authors":"A.Ye. Prysyazhniuk, D. Bazyka, N.A. Hudzenko, M. Fuzik, N. Trotsiuk, N. Babkina, O. Khukhrianska, S. A. Danevych","doi":"10.32402/dovkil2022.02.016","DOIUrl":"https://doi.org/10.32402/dovkil2022.02.016","url":null,"abstract":"There is performed a study of cancer incidence in the population affected by the Chornobyl accident. Analysis of demography situation has shown that unlike Western European countries with increasing life expectancy this index was notably decreased in Ukraine in 2005–2006 with slow growth during 2006–2019. Certainly this circumstance may influence on cancer incidence rate because the highest risk of malignant tumours is just in elderly age. Goal: to determine the frequency and risk of malignant neoplasms in groups of the population of Ukraine that were exposed to radiation as a result of the Chоrnobyl accident in the remote post-accident period. Materials and methods. The study was conducted on the basis of long-term monitoring of malignant tumours in the groups of victims – clean-up workers of 1986–1987, evacuees from the exclusion zone, residents of the territories most heavily contaminated with radionuclides. Results. There was a significant excess of the expected level of incidence of thyroid cancer among the participants in liquidation of the accident consequences (PLAC) - 4.5 times, evacuees - 3.8 times, residents of territories contaminated with radionuclides - 1.3 times. Leukaemia and lymphoma incidence rate in residents of contaminated territories increased sharply in the first years after the accident but decreased in the next years and not exceeded the level if Kyiv and Zhytomyr regions and Ukraine at whole. In a joint Ukrainian-American analytical epidemiological case-control study dose dependent excess relative risk of leukaemia (ERR/Gy) was proved in clean-up workers and defined at level 2.38 (0.49–5.87) in 1986–2006. A significant excess of the national level of incidence of breast cancer was determined only in women - PLAC in 1986–1987. In 1994–2019 SIR was 156.3% (95% CI: 141.0–171.5). Conclusions. Because latency period for different forms of radiation related malignancies might be very long further special attention should be paid not only to nosological forms mentioned above but also to cancers of the other sites.","PeriodicalId":144023,"journal":{"name":"Environment &amp; Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129976820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The state of occupational stress in medical workers, counteraction and overcoming it 医务工作者职业压力的现状、应对与克服
Pub Date : 2022-06-01 DOI: 10.32402/dovkil2022.02.053
V. Chorna, V. Makhniuk, S.M. Моhylnyi, S. Khliestova, V.M. Podolian, L. B. Furman, I. V. Larchenko, A. Chaika
Objective. To determine the manifestations and the level of predictors of the development of emotional burnout (PREV) among medical workers in the Vinnytsia region and develop preventive measures to prevent it. Materials and methods. The study involved 324 respondents - healthcare workers in the Vinnytsia region. Among the respondents were women – 82,4%, men – 17,6%. The average age of respondents among doctors was 44,06+12,2 years, among nurses – 37,2+11,4 years. The length of service in professional activities was: among doctors – 19,7 + 12,3 years and SMPs – 15,5 + 11,1 years. The psychodiagnostic method of emotional burnout by V.V. Boyko was used in the study and the adapted technique of N.E. Vodopianova. Statistical processing of the study results was performed in the licensed standardized package Statistica 6.1 for Windows with the calculation of the arithmetic mean value, the standard mean arithmetic error. The significance of the difference was assessed using Student's t-test (t). The work used content analysis of domestic and foreign scientific sources, biblio-semantic, analytical and statistical research methods. Research Results. The article analyzes the state of professional and emotional burnout/stress among medical workers in the healthcare sector in Ukraine and abroad. The chief causes of professional burnout/stress, their factors, and their consequences are highlighted. Conclusions. These research results indicate inappropriate working conditions and the presence of harmful professional factors leading to a high level of emotional exhaustion, depersonalization, and a reduction in professional achievements, which negatively affects the performance of their professional duties by every second health worker and requires them to be provided with outpatient treatment to prevent the transition of PREV syndromes and professional burnout into illness. The prospect of further research is to study the problem of professional burnout/stress, counteraction, and an effective system of mental health prevention both for medical personnel and the population of Ukraine.
目标。目的了解文尼察地区医务人员情绪倦怠(PREV)发展的表现及预测因素水平,并制定预防措施。材料和方法。这项研究涉及324名受访者——文尼察地区的卫生保健工作者。受访者中女性占84.2%,男性占17.6%。受访医生的平均年龄为44,06+ 12.2岁,受访护士的平均年龄为- 37,2+ 11.4岁。从事专业活动的年资分别为:医生- 19年、7 + 12年、3年,中等职业医师- 15年、5 + 11年、1年。本研究采用V.V. Boyko的情绪倦怠心理诊断方法和N.E. Vodopianova的适应技术。研究结果的统计处理在许可的标准化软件包Statistica 6.1 for Windows中进行,计算算术平均值,标准平均算术误差。采用学生t检验(t)来评估差异的显著性。本工作采用了国内外科学文献的内容分析、文献语义、分析和统计研究方法。研究的结果。文章分析了在乌克兰和国外的医疗保健部门医务工作者的职业和情感倦怠/压力的状态。职业倦怠/压力的主要原因,他们的因素,和他们的后果是突出。结论。这些研究结果表明,不适当的工作条件和有害的专业因素的存在导致了高水平的情绪耗竭、人格解体和专业成就的降低,这对每一名卫生工作者履行其专业职责产生了负面影响,需要为他们提供门诊治疗,以防止PREV综合征和职业倦怠转变为疾病。进一步研究的前景是研究乌克兰医务人员和人口的职业倦怠/压力问题,对策和有效的心理健康预防系统。
{"title":"The state of occupational stress in medical workers, counteraction and overcoming it","authors":"V. Chorna, V. Makhniuk, S.M. Моhylnyi, S. Khliestova, V.M. Podolian, L. B. Furman, I. V. Larchenko, A. Chaika","doi":"10.32402/dovkil2022.02.053","DOIUrl":"https://doi.org/10.32402/dovkil2022.02.053","url":null,"abstract":"Objective. To determine the manifestations and the level of predictors of the development of emotional burnout (PREV) among medical workers in the Vinnytsia region and develop preventive measures to prevent it. Materials and methods. The study involved 324 respondents - healthcare workers in the Vinnytsia region. Among the respondents were women – 82,4%, men – 17,6%. The average age of respondents among doctors was 44,06+12,2 years, among nurses – 37,2+11,4 years. The length of service in professional activities was: among doctors – 19,7 + 12,3 years and SMPs – 15,5 + 11,1 years. The psychodiagnostic method of emotional burnout by V.V. Boyko was used in the study and the adapted technique of N.E. Vodopianova. Statistical processing of the study results was performed in the licensed standardized package Statistica 6.1 for Windows with the calculation of the arithmetic mean value, the standard mean arithmetic error. The significance of the difference was assessed using Student's t-test (t). The work used content analysis of domestic and foreign scientific sources, biblio-semantic, analytical and statistical research methods. Research Results. The article analyzes the state of professional and emotional burnout/stress among medical workers in the healthcare sector in Ukraine and abroad. The chief causes of professional burnout/stress, their factors, and their consequences are highlighted. Conclusions. These research results indicate inappropriate working conditions and the presence of harmful professional factors leading to a high level of emotional exhaustion, depersonalization, and a reduction in professional achievements, which negatively affects the performance of their professional duties by every second health worker and requires them to be provided with outpatient treatment to prevent the transition of PREV syndromes and professional burnout into illness. The prospect of further research is to study the problem of professional burnout/stress, counteraction, and an effective system of mental health prevention both for medical personnel and the population of Ukraine.","PeriodicalId":144023,"journal":{"name":"Environment &amp; Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127429343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Psychogygenic principles of using health-preserving technologies in modern institutions of higher education 在现代高等教育机构中使用保健技术的心理成因原则
Pub Date : 2022-06-01 DOI: 10.32402/dovkil2022.02.032
I. Serheta, N. V. Stoian, O. Serebrennikova, I. Drezhenkova, O. Makarova
Objective: We established and scientifically substantiated the psychohygienic principles of using health-preserving technologies in modern institutions of higher education. Materials and methods. The research was conducted on the basis of National Pyrohov Memorial Medical University. A well-structured set of highly informative modern hygienic, medical-sociological, psychophysiological and psychodiagnostic methods and methods of statistical analysis were used to adequately achieve this goal. Results. The data obtained in the course of research indicate that as conceptual psychohygienic principles of effective use of health-preserving technologies in modern institutions of higher education should be noted: (1) regime-adaptive principle of application of psychohygienic components in the structure of modern health-preserving technologies, which determines the need to take into account the main regime elements of educational and extracurricular activities of students in specific conditions of the educational process, determining and constantly monitoring the level of educational adaptation and academic performance of students, especially in professionally oriented disciplines; (2) psychophysiological principle of application of psychohygienic components in the structure of modern health technologies, which is determined by the level of development of leading socially and professionally significant psychophysiological functions of the body of girls and boys; (3) personal principle of application of psychohygienic components in the structure of modern health technologies, which is related to the peculiarities of assessing the processes of formation of leading personality traits of student youth, which play an important role under the influence of both favorable and, above all, unfavorable educational factors. extracurricular activities; (4) integrative-functional principle of application of psychohygienic components in the structure of modern health technologies, which is determined by the presence of deep relationships between individual components of the functional state and adaptive capacity of young girls and young boys, which have a complex impact on health and theoreticalу- and, mainly, practically-significant components of students’ training. Conclusions. In the course of the research the leading psychohygienic principles of using health-preserving technologies in modern modern institutions of higher education have been identified and scientifically substantiated.
目的:建立并科学论证现代高等院校运用保健技术的心理卫生原则。材料和方法。这项研究是在国立焦若夫纪念医科大学的基础上进行的。为了充分实现这一目标,采用了一套结构良好、信息丰富的现代卫生、医学社会学、心理生理学和心理诊断方法以及统计分析方法。结果。在研究过程中获得的数据表明,应注意在现代高等教育机构中有效使用保健技术的概念心理卫生原则:(1)制度适应原则,即心理卫生成分在现代保健技术结构中的应用,它决定了在教育过程的特定条件下,需要考虑学生的教育和课外活动的主要制度要素,确定并不断监测学生的教育适应水平和学习成绩,特别是在专业导向学科中;(2)心理生理学原理,即心理卫生成分在现代卫生技术结构中的应用,这是由男孩和女孩身体的主要社会和专业重要心理生理功能的发展水平决定的;(3)心理卫生成分在现代卫生技术结构中的应用的个人原则,这与评价学生青年主要人格特质形成过程的特殊性有关,在有利的和不利的教育因素的影响下都起着重要作用。课外活动;(4)心理卫生成分在现代卫生技术结构中的应用的整合功能原则,这是由年轻女孩和年轻男孩的功能状态的个体成分与适应能力之间存在的深层关系决定的,这些成分对健康和学生训练的理论意义和主要是实践意义上的重要组成部分具有复杂的影响。结论。在研究过程中,确定并科学地证实了在现代高等教育机构中使用保健技术的主要心理卫生原则。
{"title":"Psychogygenic principles of using health-preserving technologies in modern institutions of higher education","authors":"I. Serheta, N. V. Stoian, O. Serebrennikova, I. Drezhenkova, O. Makarova","doi":"10.32402/dovkil2022.02.032","DOIUrl":"https://doi.org/10.32402/dovkil2022.02.032","url":null,"abstract":"Objective: We established and scientifically substantiated the psychohygienic principles of using health-preserving technologies in modern institutions of higher education. Materials and methods. The research was conducted on the basis of National Pyrohov Memorial Medical University. A well-structured set of highly informative modern hygienic, medical-sociological, psychophysiological and psychodiagnostic methods and methods of statistical analysis were used to adequately achieve this goal. Results. The data obtained in the course of research indicate that as conceptual psychohygienic principles of effective use of health-preserving technologies in modern institutions of higher education should be noted: (1) regime-adaptive principle of application of psychohygienic components in the structure of modern health-preserving technologies, which determines the need to take into account the main regime elements of educational and extracurricular activities of students in specific conditions of the educational process, determining and constantly monitoring the level of educational adaptation and academic performance of students, especially in professionally oriented disciplines; (2) psychophysiological principle of application of psychohygienic components in the structure of modern health technologies, which is determined by the level of development of leading socially and professionally significant psychophysiological functions of the body of girls and boys; (3) personal principle of application of psychohygienic components in the structure of modern health technologies, which is related to the peculiarities of assessing the processes of formation of leading personality traits of student youth, which play an important role under the influence of both favorable and, above all, unfavorable educational factors. extracurricular activities; (4) integrative-functional principle of application of psychohygienic components in the structure of modern health technologies, which is determined by the presence of deep relationships between individual components of the functional state and adaptive capacity of young girls and young boys, which have a complex impact on health and theoreticalу- and, mainly, practically-significant components of students’ training. Conclusions. In the course of the research the leading psychohygienic principles of using health-preserving technologies in modern modern institutions of higher education have been identified and scientifically substantiated.","PeriodicalId":144023,"journal":{"name":"Environment &amp; Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126870468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
On the issue of revising the regulatory framework for chemical carcinogens in the air according to the risk criterion 关于根据风险标准修订空气中化学致癌物监管框架的问题
Pub Date : 2022-06-01 DOI: 10.32402/dovkil2022.02.042
I. Chernychenko, O. Lytvychenko, V. Babii, S. Harkavyi, N. Balenko, O.Ye. Kondratenko, D. Hlavachek
The aim of the work was to analyze the risk of carcinogenic substances in populated areas and industrial zone, included in domestic regulatory frameworks, in accordance with international qualification standards, and to determine the safety level of existing hygienic standards for humans by specific oncogenic hazard criteria. Materials and methods. Bibliosemantic, bibliographic and hygienic research methods was used in the work. The results were obtained on the basis of collection and analysis of data on chemical carcinogenic compounds that are dangerous to humans, according to international directives, domestic and foreign regulatory frameworks. Carcinogenicity indicators was identified to assess the hazards of certain substances and hygienic regulatory levels. Research results and their discussion. The analysis of national and international databases on carcinogenic compounds, assessment of their physicochemical properties, dose-effect response and health effects was carried out. It was shown that today the most recognized and widespread base of the International Agency for Research on Cancer, in which based on a critical analysis of experimental and epidemiological data of more than 1000 chemical factors, their classification was carried out according to the degree of evidence of carcinogenic hazard to humans, the hygienic expression of which is carcinogenic risk. The analysis of domestic databases of hygienic standards for the permissible content of chemicals showed that only for 131 carcinogenic substances the MPC in the air is justified, however, according to the criterion of carcinogenic risk, most of them do not meet the requirements of the EU and world practices, which indicates the need for their revision. It is emphasized that one of the available and adequate methods of this task is the principle laid down in determining the relationship "concentration - risk (acceptable risk)". Conclusions. It was shown that according to the criterion of carcinogenic risk, the hygienic standards of most carcinogenic substances included in domestic regulatory air bases do not meet the requirements of the EU and international practices, which indicates the need to revise them based on acceptable risk.
这项工作的目的是根据国际资格标准,分析包括在国内监管框架内的人口稠密地区和工业区致癌物质的风险,并根据具体的致癌危害标准确定现有人类卫生标准的安全水平。材料和方法。采用文献语义学、目录学和卫生学研究方法。该结果是根据国际指令、国内和国外监管框架,在收集和分析对人类有害的化学致癌化合物数据的基础上得出的。确定了致癌性指标,以评估某些物质的危害和卫生监管水平。研究结果及其讨论。对国家和国际致癌化合物数据库进行了分析,评估了它们的理化性质、剂量效应反应和健康影响。据显示,今天国际癌症研究机构最公认和最广泛的基础是,在对1000多种化学因素的实验和流行病学数据进行批判性分析的基础上,根据对人类致癌危害的证据程度对它们进行分类,其卫生表达是致癌风险。通过对国内化学物质允许含量卫生标准数据库的分析,空气中只有131种致癌物质的MPC是合理的,然而,根据致癌风险标准,大多数不符合欧盟和世界惯例的要求,这表明需要进行修订。有人强调指出,完成这项任务的现有和适当的方法之一是确定“集中-风险(可接受的风险)”关系所规定的原则。结论。研究表明,根据致癌风险标准,国内监管基地所包含的大多数致癌物质的卫生标准不符合欧盟和国际惯例的要求,这表明需要根据可接受的风险对其进行修订。
{"title":"On the issue of revising the regulatory framework for chemical carcinogens in the air according to the risk criterion","authors":"I. Chernychenko, O. Lytvychenko, V. Babii, S. Harkavyi, N. Balenko, O.Ye. Kondratenko, D. Hlavachek","doi":"10.32402/dovkil2022.02.042","DOIUrl":"https://doi.org/10.32402/dovkil2022.02.042","url":null,"abstract":"The aim of the work was to analyze the risk of carcinogenic substances in populated areas and industrial zone, included in domestic regulatory frameworks, in accordance with international qualification standards, and to determine the safety level of existing hygienic standards for humans by specific oncogenic hazard criteria. Materials and methods. Bibliosemantic, bibliographic and hygienic research methods was used in the work. The results were obtained on the basis of collection and analysis of data on chemical carcinogenic compounds that are dangerous to humans, according to international directives, domestic and foreign regulatory frameworks. Carcinogenicity indicators was identified to assess the hazards of certain substances and hygienic regulatory levels. Research results and their discussion. The analysis of national and international databases on carcinogenic compounds, assessment of their physicochemical properties, dose-effect response and health effects was carried out. It was shown that today the most recognized and widespread base of the International Agency for Research on Cancer, in which based on a critical analysis of experimental and epidemiological data of more than 1000 chemical factors, their classification was carried out according to the degree of evidence of carcinogenic hazard to humans, the hygienic expression of which is carcinogenic risk. The analysis of domestic databases of hygienic standards for the permissible content of chemicals showed that only for 131 carcinogenic substances the MPC in the air is justified, however, according to the criterion of carcinogenic risk, most of them do not meet the requirements of the EU and world practices, which indicates the need for their revision. It is emphasized that one of the available and adequate methods of this task is the principle laid down in determining the relationship \"concentration - risk (acceptable risk)\". Conclusions. It was shown that according to the criterion of carcinogenic risk, the hygienic standards of most carcinogenic substances included in domestic regulatory air bases do not meet the requirements of the EU and international practices, which indicates the need to revise them based on acceptable risk.","PeriodicalId":144023,"journal":{"name":"Environment &amp; Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125141339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
期刊
Environment &amp; Health
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1