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To study the incidence of intraventricular Hemorrhage in preterm neonates 目的探讨早产儿脑室内出血的发生率
Pub Date : 2023-01-01 DOI: 10.33545/26643685.2023.v6.i1a.193
Dr. Ankita Thakur, Dr. Kirandeep Sodhi, Dr. SK Meghana, Dr. Nidhi Chadha
Introduction: Intraventricular Haemorrhage is the most common forms of brain injury in preterm neonates 1 , more commonly seen in the smallest and most preterm neonates contributing to mortality, morbidity during the time of stay in hospital. IVH among VLBW is common with the incidence of around 20-25% out of which around 2/3 rd are mild to moderate in severity with [grade 1-2]. Objective: To study the incidence of intraventricular hemorrhage in preterm neonates. Methods: This is a hospital based, prospective, observational study. Total 100 inborn preterm neonates fulfilling the inclusion criteria were screened for IVH using USG cranium as modality of choice. Results: Distribution of study subjects as per IVH on USG showed 86% of the preterm neonates did not have Intra ventricular hemorrhage while the rest 14% had Intra ventricular Hemorrhage (IVH). Among those 14 neonates who had IVH, 11 neonates (78.6%) had Grade – I IVH and the remaining 21.4% had Grade – II IVH. Conclusion: On the basis of our present study the prevalence of IVH among preterm neonates in the present study was high (14%). Majority of them had grade I IVH. It was particularly high among those of gestational age ≥ 30 weeks. Apnea has a significant association with presence of IVH.
脑室内出血是早产新生儿中最常见的脑损伤形式1,最常见于最小和最多的早产儿,可导致住院期间的死亡率和发病率。IVH在VLBW中很常见,发生率约为20-25%,其中约2/3为轻度至中度[1-2级]。目的:探讨早产儿脑室内出血的发生率。方法:这是一项基于医院的前瞻性观察性研究。总共100名符合纳入标准的出生早产儿使用USG颅骨作为选择方式进行IVH筛查。结果:研究对象在USG上的IVH分布显示,86%的早产儿没有脑室出血,其余14%有脑室出血(IVH)。14例IVH患儿中,11例(78.6%)为I级IVH,其余21.4%为II级IVH。结论:根据我们目前的研究,本研究中早产儿IVH的患病率很高(14%)。他们大多数患有I级IVH。在孕龄≥30周的孕妇中尤其高。呼吸暂停与IVH存在显著相关。
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引用次数: 0
Study of ‘Fever without source’ in Infants and young children 婴幼儿“无源发热”的研究
Pub Date : 2023-01-01 DOI: 10.33545/26643685.2023.v6.i1a.191
Dr. Syed Aafaq Zishan Abid, S. Kumbhar, Kishan G. Takrani, Arshi Ishteyaq
Background: Fever is one of the most common as well as trouble some manifestation in paediatric practice, both for paediatricians and parents. It is a simply noted an good marker of illness. Fever could be benign presentation of simple viral infection or it can be a presentation of life threating bacterial infection like sepsis and pyogenic meningitis. It is a common, terrifying, physiologic response that has been the source of biggest complaint throughout the history of paediatric practice. Methods: Analytical Cross-sectional Study. Results: In present study, 60 cases were included. Age group between 1-3 months was 3.3% (n=2) of the patients, 4-36 months was 31.6% (n=19) of the patients and 37-60 months was 65% (n=39) of the patients. Female n=31 more than male n=29. Final diagnosis was of UTI in 11.6% (n=7) of the cases taken in the study. Sepsis was diagnosed in 10% (n=6), Rickettsial Fever was diagnosed in 13.3% (n=8), Typhoid fever was diagnosed in 11.6% (n=7), Dengue was diagnosed in 3.3% (n=2) and Kawasaki’s disease was diagnosed in 5% (n=3) of the patients. Rest 45% (n=27) of the patients where cause was unknown. Conclusion: UTI, Rickettsial infection and Enteric fever were among common cause of Fever without source. “Fever without source’ pose a diagnostic dilemma and require detail evaluation to detect underlying etiology of infection, Systemic illness or Occult bacteremia. Majority of the patients no etiology was found in our study, Inspite of thorough investigation.
背景:发烧是儿科医生和家长在儿科实践中最常见和最麻烦的表现之一。这是一种简单明了的疾病的良好标志。发烧可能是单纯病毒感染的良性表现,也可能是威胁生命的细菌感染的表现,如败血症和化脓性脑膜炎。这是一种常见的、可怕的生理反应,在整个儿科实践史上一直是最大的投诉来源。方法:分析性横断面研究。结果:本研究共纳入60例。年龄在1 ~ 3月龄的患者占3.3% (n=2), 4 ~ 36月龄的患者占31.6% (n=19), 37 ~ 60月龄的患者占65% (n=39)。女性n=31比男性n=29多。在本研究中,11.6% (n=7)的病例最终诊断为UTI。其中败血症占10% (n=6),立克次体热占13.3% (n=8),伤寒占11.6% (n=7),登革热占3.3% (n=2),川崎病占5% (n=3)。其余45% (n=27)的患者病因不明。结论:尿路感染、立克次体感染和肠道热是无源发热的常见原因。“无源发热”造成了诊断困境,需要详细评估以发现感染、全身性疾病或隐匿性菌血症的潜在病因。在我们的研究中,尽管进行了彻底的调查,但大多数患者没有发现病因。
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引用次数: 0
Nasal colonazation in relatively healthy children by clinical examination in Al-Zahraa teaching hospital in Al-Najaf City 纳杰夫市Al-Zahraa教学医院临床检查中相对健康儿童的鼻腔定植
Pub Date : 2023-01-01 DOI: 10.33545/26643685.2023.v6.i1a.196
Dr. Teba Kasim Mohamed, Dr. Firas Salam Fakhri, Faris M. Al-haris
Background: Nasal colonization by bacterial pathogens is linked to the risk of invasive infections, which are a leading cause of mortality in children globally. While viruses are the primary cause of respiratory tract infections (RTIs), bacteria contribute to localized infections such as sinusitis, pneumonia, and meningitis. Most colonization remains asymptomatic but can become invasive in vulnerable hosts. Study Objective: The goal of this study was to screen for asymptomatic nasal colonization by potential bacterial pathogens and analyze the correlation between carriage rate and various socio-demographic factors. Patients and Method: This cross-sectional study involved healthy children to examine nasal carriage of bacterial pathogens. The study was conducted at the laboratory unit in Al-Zahra Teaching Hospital for Maternity and Children in Al Najaf city, Iraq, from January to October 2016. Nasal swabs were tested for five prevalent bacterial pathogens: Streptococcus pneumoniae, Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella catarrhalis, and Staphylococcus aureus. A total of 100 healthy children (1-< 12 years old) were included, and bacteria were identified using standard techniques. Results: The overall carriage rate of nasal pathogens was 33%, with Streptococcus pneumoniae and Staphylococcus aureus accounting for 11% and 22%, respectively. The study found no statistically significant differences between age, gender, residency, social level, and attendance concerning the carriage of these two bacteria. Conclusions: The study revealed nasal colonization of common pathogenic bacteria, including Staphylococcus aureus and Streptococcus pneumoniae. However, no significant relationships were found between nasal swab results and age, gender, residency, social level, and attendance, as all p-values were greater than 0.05.
背景:细菌性病原体的鼻腔定植与侵袭性感染的风险有关,这是全球儿童死亡的主要原因。虽然病毒是呼吸道感染(RTIs)的主要原因,但细菌也会导致鼻窦炎、肺炎和脑膜炎等局部感染。大多数定植是无症状的,但可以侵入脆弱的宿主。研究目的:本研究的目的是筛查潜在的无症状细菌病原体的鼻腔定植,并分析携带率与各种社会人口因素的相关性。患者和方法:本横断面研究涉及健康儿童,以检查细菌病原体的鼻腔携带。该研究于2016年1月至10月在伊拉克Al Najaf市Al- zahra妇幼教学医院的实验室进行。对鼻拭子进行了五种流行的细菌病原体检测:肺炎链球菌、流感嗜血杆菌、副流感嗜血杆菌、卡他莫拉菌和金黄色葡萄球菌。共纳入100名健康儿童(1-< 12岁),采用标准技术鉴定细菌。结果:鼻腔病原菌总体携带率为33%,其中肺炎链球菌和金黄色葡萄球菌分别占11%和22%。研究发现,年龄、性别、居住地、社会水平和出勤率在携带这两种细菌方面没有统计学上的显著差异。结论:该研究揭示了常见致病菌的鼻腔定植,包括金黄色葡萄球菌和肺炎链球菌。然而,鼻拭子结果与年龄、性别、居住地、社会水平和出勤率之间没有显著关系,p值均大于0.05。
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引用次数: 0
Clinical profile and outcome of children with diabetic ketoacidosis admitted in a tertiary care centre in kerala during the pre and post COVID period 喀拉拉邦三级保健中心在COVID前后期间收治的糖尿病酮症酸中毒儿童的临床概况和结果
Pub Date : 2023-01-01 DOI: 10.33545/26643685.2023.v6.i1a.189
Dr. Mathews E Kuriakose, Dr. Johny Vakayil Francis, Ditty George, Dr.A. Chandra Babu
Objective: To study clinical profile and outcome of children admitted with diabetic ketoacidosis in our tertiary care centre during the pre and post covid period (Jan 2016 – Jan 2022). Materials and Methods: Hospital-based cohort study among the children admitted with DKA in the department of Paediatrics. We abstracted the data of children, satisfying the inclusion criteria as per the pre-designed proforma based on ISPAD 2018 guidelines. Participants: 46 children admitted with diagnosis of DKA during the study period, in a tertiary care centre in Kerala. Results: Total of 46 admissions with DKA including 16 readmissions in 30 children were enrolled in the study. Majority (95.65%) were Type 1 DM with mean age of 11.6 years and male to female ratio of 1.1:1. There were 11.5 admission per year after the Covid 19 outbreak, compared to 5.8 cases per year during the pre-covid period. Most of the patients (60.9%) had only a short duration of symp toms (≤ 3 days) at presentation, and vomiting was the commonest symptom (63%), followed by polyuria, polydipsia (60.9%). 47.8% patients presented with mild DKA followed by 34.8% as severe DKA and majority (60.9%) needed 4 to 7 days of hospital stay. Conclusion: DKA is a leading cause of morbidity and mortality in children with diabetes. There is a significant increase in the frequency of children getting admitted with DKA in the post Covid period which may be due to the delay in diagnosing the condition because of sedentary life style during lockdown, unhealthy eating habits and poor utilization of health care system by the public during the early surge of COVID peak.
目的:研究2016年1月至2022年1月期间我院三级保健中心收治的糖尿病酮症酸中毒患儿的临床概况和转诊结果。材料和方法:在儿科住院的DKA患儿中进行基于医院的队列研究。我们根据ISPAD 2018指南,按照预先设计的形式提取符合纳入标准的儿童数据。参与者:46名在喀拉拉邦三级保健中心诊断为DKA的儿童在研究期间入院。结果:共纳入46例DKA入院患者,其中16例患儿为30例再入院患者。1型糖尿病占多数(95.65%),平均年龄11.6岁,男女比例为1.1:1。Covid - 19爆发后,每年有11.5例入院,而在Covid - 19爆发前,每年有5.8例入院。大多数患者(60.9%)就诊时症状持续时间较短(≤3天),呕吐是最常见的症状(63%),其次是多尿、烦渴(60.9%)。47.8%的患者表现为轻度DKA, 34.8%的患者表现为重度DKA,多数患者(60.9%)住院时间为4 ~ 7天。结论:DKA是儿童糖尿病发病和死亡的主要原因。新冠肺炎后儿童DKA入院频率显著增加,这可能是由于封锁期间久坐不动的生活方式、不健康的饮食习惯以及公众在新冠肺炎高峰早期对医疗保健系统的利用不足导致诊断延迟。
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引用次数: 0
Iron pill induced gastritis in children with iron deficiency anemia 铁丸致缺铁性贫血患儿胃炎
Pub Date : 2022-07-01 DOI: 10.33545/26643685.2022.v5.i2a.185
Dr. N Bragadeeshwaran, Dr. Archana, D. Somasekar
Iron deficiency anemia (IDA) is the most common nutritional anemia in India, which is managed with oral supplementation of iron. Gastritis induced with these iron pills is a common complication following of oral iron (ferrous sulfate) supplementation. So proper care must be taken when iron supplementation is prescribed. When the side effects are encountered, oral iron is stopped, and treatment should be started immediately
缺铁性贫血(IDA)是印度最常见的营养性贫血,通过口服补铁来治疗。这些铁丸引起的胃炎是口服铁(硫酸亚铁)补充后的常见并发症。因此,在服用补铁剂时,必须格外小心。当出现副作用时,应停止口服铁,并立即开始治疗
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引用次数: 0
Factors associated with hospital mortality of children aged 1 to 60 months in Guédiawaye, Senegal 与塞内加尔古萨迪亚瓦耶1至60个月儿童住院死亡率相关的因素
Pub Date : 2022-07-01 DOI: 10.33545/26643685.2022.v5.i2a.184
Diouf Jbn, Tall Ct, Niassy Ac, Bassolé Pr, Cissé Fz
To determine the characteristics of hospital morbidity and mortality in the paediatric department of the Roi Baudouin Hospital in children aged 1 to 60 months, a retrospective descriptive and analytical study from 1 January 2018 to 31 December 2021 was conducted. The in-hospital mortality rate was 0.96% and the factors associated with death were the age group 1-12 months (p<0.001 and 0R=5.33), acute malnutrition (p=0.007 and OR=3.37) and cardiac disease (p=0.017 and 0R=5.1).
为了确定1至60个月大的儿童在博杜安国王医院儿科的医院发病率和死亡率特征,从2018年1月1日至2021年12月31日进行了一项回顾性描述性和分析性研究。住院死亡率为0.96%,与死亡相关的因素为1 ~ 12月龄组(p<0.001, r =5.33)、急性营养不良组(p=0.007, OR=3.37)、心脏病组(p=0.017, r =5.1)。
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引用次数: 0
To investigate the clinico-demographic profile and risk variables linked with measles patients 调查与麻疹患者相关的临床人口学概况和风险变量
Pub Date : 2022-07-01 DOI: 10.33545/26643685.2022.v5.i2a.197
Dr. Narinder Singh
Aim: The purpose of this study is to investigate the clinico-demographic profile and risk variables linked with measles patients. Material and Methods: This hospital-based cross-sectional study was conducted among children who presented in the Paediatric OPD over the course of a year. Children who satisfied the criteria for clinical measles as per WHO criteria i.e Fever with rash lasting at least 3 days and cough/coryza (running nose), or conjunctivitis (red eyes) were included in the study. The research comprised 240 children who presented in OPD throughout the study period. 82 of the 240 children’ were admitted in the pediatric ward had one or more complications of the measles. Results: It was found that 82 cases of clinical measles, with a frequency of 34.17%, were admitted out of a total of 240 cases. The attack rate (Table 1) was highest (71.95%) in the age range of 0 – 5 years, as is also evident from the table. Male child (43.90%) and female child (56.10%) were shown to have a little advantage. The majority of children who contracted measles were between the ages of 1 - 5 (57.32%) and 5 - 10 (21.95%), respectively. Children who live in rural slums are more likely to be attacked (79.27%). The majority of measles cases (50%) are associated with lower socioeconomic level. Only 24.39% of children with measles attacks were exclusively breastfed for initial six months according to research. In 29 instances (35.36%) the immunization status was "complete," whereas 50% of the youngsters (14.63%) were only partly immunized. With the exception of 8 measles cases, all were malnourished with category II and above. Conclusion: The vast majority of the cases had been found in children who had not been vaccinated, which indicates that vaccination coverage should be increased. In addition to this, there were cases found in children who had been vaccinated, which indicates that there is a possibility of a vaccine failing in older children and the necessity of including a second dose of vaccination as quickly as possible in the immunisation programme.
目的:本研究的目的是调查与麻疹患者相关的临床人口学概况和风险变量。材料和方法:这项以医院为基础的横断面研究是在儿科门诊就诊的儿童中进行的。符合世卫组织标准的临床麻疹标准的儿童,即发烧并皮疹持续至少3天,咳嗽/鼻塞(流鼻涕)或结膜炎(红眼)被纳入研究。该研究包括240名在整个研究期间出现在门诊的儿童。240名儿童中有82名患有一种或多种麻疹并发症。结果:在240例临床麻疹病例中,共收治82例,发病率为34.17%。发病率(表1)在0 - 5岁年龄段最高(71.95%),从表中也可以明显看出。男童(43.90%)和女童(56.10%)有轻微优势。麻疹发病儿童以1 ~ 5岁(57.32%)和5 ~ 10岁(21.95%)为主。生活在农村贫民窟的儿童更容易受到攻击(79.27%)。大多数麻疹病例(50%)与较低的社会经济水平有关。根据研究,只有24.39%的麻疹发作儿童在最初6个月内得到纯母乳喂养。在29例(35.36%)中,免疫状态是“完全的”,而50%的青少年(14.63%)仅部分免疫。除8例麻疹病例外,所有病例均为二类及以上营养不良。结论:绝大多数病例发生在未接种疫苗的儿童中,应提高疫苗接种覆盖率。除此之外,在接种过疫苗的儿童中发现了一些病例,这表明疫苗有可能在年龄较大的儿童中失效,有必要在免疫方案中尽快包括第二剂疫苗接种。
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引用次数: 0
An interesting case of Anti-N-Methyl-D-Aspartate receptor encephalitis 一个有趣的抗n -甲基- d -天冬氨酸受体脑炎病例
Pub Date : 2022-07-01 DOI: 10.33545/26643685.2022.v5.i2a.186
Dr. Hashma Mohammed P, Nasin Usman, S. Ramesh, S. S
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引用次数: 0
Children's hip discomfort from the uncommon etiology of van neck-odelberg illness 儿童髋部不适的罕见病因van neck-odelberg病
Pub Date : 2022-07-01 DOI: 10.33545/26643685.2022.v5.i2a.195
Dr. Satyasree Devineni, Dr. S Nagesh
Introduction: Pain in the pediatric pelvis is often misinterpreted as an unusual ossification pattern of the ischiopubic synchondrosis, also known as van neck-odelberg illness. The primary symptom is an odd hip discomfort in one (rarely both), which may come on suddenly or after overusing the leg. This pain may restrict mobility or cause limping. Describe the clinical and radiological features of this uncommon and sometimes misunderstood illness is the aim of our essay. Materials and Methods: These young patients are often over-studied with several unneeded instrumental examinations, such as hip ultrasounds, radiography, magnetic resonance or computer tomography scans, and other invasive procedures, due to the non-specificity of their complaints. The straightforward radiograph may detect this problem, however, particularly in males, those results are often negative due to the reproductive system's exterior protection. Non-steroidal anti-inflammatory drugs (NSAIDs) and rest from physical activity are the major treatments during the acute phase of this clinical illness, and the symptoms go away in around 1-2 weeks. In a few years, the radiological results will return to normal. Results and Conclusion: A youngster who presents to the emergency department complaining of severe hip pain is never an easy scenario. Understanding this incorrect diagnosis might help you avoid needless instrumental tests.
儿童骨盆疼痛常被误解为坐骨耻骨软骨联合症的异常骨化模式,也被称为van neck-odelberg病。主要症状是一侧髋关节奇怪的不适(很少同时出现),这可能是突然出现的,也可能是过度使用腿部后出现的。这种疼痛可能会限制活动或导致跛行。描述临床和放射特征的这种不常见的,有时被误解的疾病是我们的文章的目的。材料和方法:由于这些年轻患者的主诉不具有特异性,他们经常被过度研究了一些不必要的仪器检查,如髋关节超声、x线摄影、磁共振或计算机断层扫描,以及其他侵入性手术。直接的x光片可以检测到这个问题,然而,特别是在男性中,由于生殖系统的外部保护,这些结果通常是阴性的。非甾体抗炎药(NSAIDs)和停止体育活动是该病急性期的主要治疗方法,症状约在1-2周内消失。几年后,放射结果将恢复正常。结果和结论:一个年轻人到急诊科抱怨严重的髋关节疼痛从来都不是一件容易的事情。了解这种不正确的诊断可能有助于您避免不必要的仪器检查。
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引用次数: 0
Abnormal gait as primary presentation of corpus callosum agenesis 步态异常是胼胝体发育不全的主要表现
Pub Date : 2022-07-01 DOI: 10.33545/26643685.2022.v5.i2a.187
Dr. Shreyansh Valjiyani, Dr. Srishti Gautam
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引用次数: 0
期刊
International Journal of Paediatrics and Geriatrics
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