Pub Date : 2021-01-01DOI: 10.33545/26643685.2021.v4.i1c.142
Banothu Sudhakar, Venu Akkala
Background: Febrile seizures is considered a "syndrome" because it fulfils several characteristics that are similar among affected children. Febrile Seizure generally occurs within a restricted age range. The majority of children with Febrile Seizure show normal neurological and structural development after the episode. Objectives: To evaluate risk of bacteraemia and other factors for febrile seizures. Methods: The present study conducted in Department of Paediatrics at Kakatiya Medical College/Mahatma Gandhi Memorial Hospital-Warangal, January 2019 to December 2020, 50 children in the age group of 06 months to 5 years with febrile seizures were studied. It is a prospective observational study so no potential risk is involved in this study. Results: In this study of the 50 cases, 46 cases did not yield any growth on blood culture. Of the 04 cases with bacteremia, only 03 cases had significant bacteremia which had 02 Streptococcus pneumonia as the infecting organism and 01 H. Influenza. The other 01 case grows coagulase negative Staphylococcus aureus as the organism which was a contaminant. Conclusion: Even though viruses form major etiological agents for febrile convulsions, occult bacteraemia should be ruled out in all children presenting with febrile convulsions. Children with a positive family history of afebrile convulsion should be followed up and evaluated closely as they can develop epilepsy at a later date.
{"title":"A study on febrile convulsions with special reference to incidence of bacteremia","authors":"Banothu Sudhakar, Venu Akkala","doi":"10.33545/26643685.2021.v4.i1c.142","DOIUrl":"https://doi.org/10.33545/26643685.2021.v4.i1c.142","url":null,"abstract":"Background: Febrile seizures is considered a \"syndrome\" because it fulfils several characteristics that are similar among affected children. Febrile Seizure generally occurs within a restricted age range. The majority of children with Febrile Seizure show normal neurological and structural development after the episode. Objectives: To evaluate risk of bacteraemia and other factors for febrile seizures. Methods: The present study conducted in Department of Paediatrics at Kakatiya Medical College/Mahatma Gandhi Memorial Hospital-Warangal, January 2019 to December 2020, 50 children in the age group of 06 months to 5 years with febrile seizures were studied. It is a prospective observational study so no potential risk is involved in this study. Results: In this study of the 50 cases, 46 cases did not yield any growth on blood culture. Of the 04 cases with bacteremia, only 03 cases had significant bacteremia which had 02 Streptococcus pneumonia as the infecting organism and 01 H. Influenza. The other 01 case grows coagulase negative Staphylococcus aureus as the organism which was a contaminant. Conclusion: Even though viruses form major etiological agents for febrile convulsions, occult bacteraemia should be ruled out in all children presenting with febrile convulsions. Children with a positive family history of afebrile convulsion should be followed up and evaluated closely as they can develop epilepsy at a later date.","PeriodicalId":144032,"journal":{"name":"International Journal of Paediatrics and Geriatrics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126101101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.33545/26643685.2021.v4.i1c.144
Umesh Kumar, R. Singh
Introduction: Clinical investigations of childhood tuberculosis (TB) and treatment are challenged by the paucibacillary nature of the disease and serious side effects of standard anti-TB drugs. An adjuvant therapy may facilitate the efficacy and downgrade the occurrence of side effects associated with long-term therapy. Objective: To investigate the efficacy of beta-sitosterol (BS) as adjuvant therapy to standard anti-TB drugs in children with TB. Methods: Children in the age range of 6 to 18 years who were diagnosed with TB are enrolled in this randomised clinical study. Enrolled childrens were divided into two groups to receive either BS or placebo. Sputum and blood samples were collected after every month to assess the level of infection (Positive or negative) and evaluation of different blood related complications, respectively. Adverse events were evaluated in each patient and noted. Results: BS adjuvant therapy resulted in an early negative test for TB as compared to placebo therapy. Significant difference was noted in the patients positive for TB test from month 3 to 6. Furthermore, the BS group showed greater improvements on radiological examination than the placebo group. Comparing the BS group to the placebo group, the BS group showed improvements in hemoglobin, haematocrit, neutrophil count, serum globulin, creatinine, and urea. The overall treatment completion rates were higher in the BS-therapy group than the placebo group with comparatively lower incidence for side effects such as hepatotoxicity. Conclusion: Adjuvant BS with standard anti-TB drug therapy had the same impact on early infection mitigation and side effect incidence as standard therapy in children aged 6 to 12. to 18 years. Treatment completion was higher in the adjuvant group than the placebo group and was also safer.
{"title":"Clinical efficacy of beta-sitosterol as adjuvant therapy for the treatment of tuberculosis in children","authors":"Umesh Kumar, R. Singh","doi":"10.33545/26643685.2021.v4.i1c.144","DOIUrl":"https://doi.org/10.33545/26643685.2021.v4.i1c.144","url":null,"abstract":"Introduction: Clinical investigations of childhood tuberculosis (TB) and treatment are challenged by the paucibacillary nature of the disease and serious side effects of standard anti-TB drugs. An adjuvant therapy may facilitate the efficacy and downgrade the occurrence of side effects associated with long-term therapy. Objective: To investigate the efficacy of beta-sitosterol (BS) as adjuvant therapy to standard anti-TB drugs in children with TB. Methods: Children in the age range of 6 to 18 years who were diagnosed with TB are enrolled in this randomised clinical study. Enrolled childrens were divided into two groups to receive either BS or placebo. Sputum and blood samples were collected after every month to assess the level of infection (Positive or negative) and evaluation of different blood related complications, respectively. Adverse events were evaluated in each patient and noted. Results: BS adjuvant therapy resulted in an early negative test for TB as compared to placebo therapy. Significant difference was noted in the patients positive for TB test from month 3 to 6. Furthermore, the BS group showed greater improvements on radiological examination than the placebo group. Comparing the BS group to the placebo group, the BS group showed improvements in hemoglobin, haematocrit, neutrophil count, serum globulin, creatinine, and urea. The overall treatment completion rates were higher in the BS-therapy group than the placebo group with comparatively lower incidence for side effects such as hepatotoxicity. Conclusion: Adjuvant BS with standard anti-TB drug therapy had the same impact on early infection mitigation and side effect incidence as standard therapy in children aged 6 to 12. to 18 years. Treatment completion was higher in the adjuvant group than the placebo group and was also safer.","PeriodicalId":144032,"journal":{"name":"International Journal of Paediatrics and Geriatrics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114018484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-01DOI: 10.33545/26643685.2022.v5.i2a.180
Dr. Mohit Poddar, Dr. Neha Agrawal
Background: The present study was conducted for assessing the role of ultrasound in diagnosis of pneumonia in children. Materials and Methods: A total of 50 children within the age range of 5 years to 15 years were included in the present study. Written consent was obtained from the parents/guardians of all the patients after explaining in detail the entire research protocol. Only those subjects were included in the present study in which clinical signs and symptoms were suggestive of pneumonia. Radiographic examination was carried out in all the patients. Detailed demographic and clinical history of all the patients was also recorded. Ultrasound was done in all the patients. Results: After doing chest radiographic analysis, it was seen that pneumonia was confirmed in 82 percent of the cases. On ultrasonographic assessment, it was seen that pneumonia was confirmed in 92 percent of the cases. In five patients, with negative chest radiographic findings and positive ultrasound findings, diagnosis was confirmed by chest radiographic. Conclusion: Chest ultrasound is a reliable tool for the diagnosis of pneumonia, probably being superior to chest radiography.
{"title":"Assessment of role of Ultrasound in diagnosis of pneumonia in children","authors":"Dr. Mohit Poddar, Dr. Neha Agrawal","doi":"10.33545/26643685.2022.v5.i2a.180","DOIUrl":"https://doi.org/10.33545/26643685.2022.v5.i2a.180","url":null,"abstract":"Background: The present study was conducted for assessing the role of ultrasound in diagnosis of pneumonia in children. Materials and Methods: A total of 50 children within the age range of 5 years to 15 years were included in the present study. Written consent was obtained from the parents/guardians of all the patients after explaining in detail the entire research protocol. Only those subjects were included in the present study in which clinical signs and symptoms were suggestive of pneumonia. Radiographic examination was carried out in all the patients. Detailed demographic and clinical history of all the patients was also recorded. Ultrasound was done in all the patients. Results: After doing chest radiographic analysis, it was seen that pneumonia was confirmed in 82 percent of the cases. On ultrasonographic assessment, it was seen that pneumonia was confirmed in 92 percent of the cases. In five patients, with negative chest radiographic findings and positive ultrasound findings, diagnosis was confirmed by chest radiographic. Conclusion: Chest ultrasound is a reliable tool for the diagnosis of pneumonia, probably being superior to chest radiography.","PeriodicalId":144032,"journal":{"name":"International Journal of Paediatrics and Geriatrics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125695921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-01DOI: 10.33545/26643685.2020.v3.i2c.104
Anupama Pandey, D. Dc
The spectrum of organisms that cause neonatal sepsis changes over time and varies from region to region. It can even vary from hospital to hospital in the same city. This is due to the changing pattern of antibiotic use and changes in lifestyle. Gram negative organisms were the most common cause of neonatal sepsis in Europe and America in the 1960s. A prospective hospital based study over a period of one year was carried out at neonatal intensive care unit of our hospital, a tertiary care centre. At least 20% deliveries require nursery admission. All neonates born at the hospital and presenting with signs and symptoms of sepsis or born to mothers with potential risk factors for sepsis were investigated for sepsis. All the neonates diagnosed to have culture positive sepsis or clinical sepsis with multidrug resistant organisms were included as study cases. The most common organism was CONS accounting for 32.79% followed by Klebsiella species (16.39%) Staph aureus (14.75%). All the CONS positive cultures were non MDR (100%). Whereas 70% of the Klebsiella species and 100% of the Staph species were MDR.
{"title":"The prevalence of sepsis in neonates caused by multidrug resistant bacteria","authors":"Anupama Pandey, D. Dc","doi":"10.33545/26643685.2020.v3.i2c.104","DOIUrl":"https://doi.org/10.33545/26643685.2020.v3.i2c.104","url":null,"abstract":"The spectrum of organisms that cause neonatal sepsis changes over time and varies from region to region. It can even vary from hospital to hospital in the same city. This is due to the changing pattern of antibiotic use and changes in lifestyle. Gram negative organisms were the most common cause of neonatal sepsis in Europe and America in the 1960s. A prospective hospital based study over a period of one year was carried out at neonatal intensive care unit of our hospital, a tertiary care centre. At least 20% deliveries require nursery admission. All neonates born at the hospital and presenting with signs and symptoms of sepsis or born to mothers with potential risk factors for sepsis were investigated for sepsis. All the neonates diagnosed to have culture positive sepsis or clinical sepsis with multidrug resistant organisms were included as study cases. The most common organism was CONS accounting for 32.79% followed by Klebsiella species (16.39%) Staph aureus (14.75%). All the CONS positive cultures were non MDR (100%). Whereas 70% of the Klebsiella species and 100% of the Staph species were MDR.","PeriodicalId":144032,"journal":{"name":"International Journal of Paediatrics and Geriatrics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132555058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-01DOI: 10.33545/26643685.2020.v3.i2a.80
Bushra Nasreen
Background: Thalassemia major is one of the most common genetically transmitted diseases in the world and is associated with reduced synthesis of structurally normal hemoglobin. -thalassemia is an autosomal recessive single gene disorder. Keeping this in mind, present study was undertaken to study the growth pattern of transfusion dependent thalassaemic children and to assess the effect serum ferritin, haemoglobin levels on physical growth pattern in thalassemic children. Methods: A prospective observational study was done on 52 thalassaemic patients (aged 2 years-12 years) who attended Department of Pediatrics. Anthropometric measurements like weight and height were taken from all patients. Sexual maturity rating was done in girls 10 years and boys11 years. Lab parameters included pre-transfusion hemoglobin (Hb) and serum ferritin. Percentiles for weight, height and body mass index were calculated using WHO (2007) reference data. Results: Among 52 transfusion dependent thalassemic children majority i.e. 35(67.3%) were more than 6years.Mean age was 8 3.05. Majority of children i.e. 32(61.6%) were male. Mean age of diagnosis was 9.2 months, youngest case being diagnosed at 3rd month, and oldest being at 20 months. Among 52 children most of them are born to non-consanguineous couple. Majority of the children had pre-transfusion haemoglobin in the range of 5-7 gm%. Among 52 children 61.6 % (n=32) had mean serum ferritin more than 2500, and 38.4% (n=20) had mean serum ferritin value less than 2500. The present results showed that, Among 52 children according to IAP standards weight for age less than 50th percentile was 86.5% (n=45) and more than 50th percentile was 13.5%(n=7). Among 45(86.5%) children who had less than 50th percentile weight for age, 19.2 % (n=10) children were less than 6 years of age, remaining 67.3% (n=35) children belongs to 7 to 12 years of age. Among weight for age
{"title":"A prospective study on growth pattern and effect of serum ferritin, haemoglobin levels on physical growth inthalassemic childern","authors":"Bushra Nasreen","doi":"10.33545/26643685.2020.v3.i2a.80","DOIUrl":"https://doi.org/10.33545/26643685.2020.v3.i2a.80","url":null,"abstract":"Background: Thalassemia major is one of the most common genetically transmitted diseases in the world and is associated with reduced synthesis of structurally normal hemoglobin. -thalassemia is an autosomal recessive single gene disorder. Keeping this in mind, present study was undertaken to study the growth pattern of transfusion dependent thalassaemic children and to assess the effect serum ferritin, haemoglobin levels on physical growth pattern in thalassemic children. Methods: A prospective observational study was done on 52 thalassaemic patients (aged 2 years-12 years) who attended Department of Pediatrics. Anthropometric measurements like weight and height were taken from all patients. Sexual maturity rating was done in girls 10 years and boys11 years. Lab parameters included pre-transfusion hemoglobin (Hb) and serum ferritin. Percentiles for weight, height and body mass index were calculated using WHO (2007) reference data. Results: Among 52 transfusion dependent thalassemic children majority i.e. 35(67.3%) were more than 6years.Mean age was 8 3.05. Majority of children i.e. 32(61.6%) were male. Mean age of diagnosis was 9.2 months, youngest case being diagnosed at 3rd month, and oldest being at 20 months. Among 52 children most of them are born to non-consanguineous couple. Majority of the children had pre-transfusion haemoglobin in the range of 5-7 gm%. Among 52 children 61.6 % (n=32) had mean serum ferritin more than 2500, and 38.4% (n=20) had mean serum ferritin value less than 2500. The present results showed that, Among 52 children according to IAP standards weight for age less than 50th percentile was 86.5% (n=45) and more than 50th percentile was 13.5%(n=7). Among 45(86.5%) children who had less than 50th percentile weight for age, 19.2 % (n=10) children were less than 6 years of age, remaining 67.3% (n=35) children belongs to 7 to 12 years of age. Among weight for age","PeriodicalId":144032,"journal":{"name":"International Journal of Paediatrics and Geriatrics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134532320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-01DOI: 10.33545/26643685.2020.v3.i2c.111
Vidhyadhara Naik Tl, S. K. Jena, N. Mishra
Background: The worldwide incidence of CH ranges from 1 in 3000 to 1 in 4000 live newborn. However, varied incidence has been found from state, regional, and national screening programs. Objective: to know the incidence of Congenital Hypothyroidism and associated congenital anomalies in this part of the country, which is necessary to understand the burden of congenital hypothyroidism to the society. Setting: Primary serum TSH measurement in screening neonates with backup thyroxine (T 4 ) determination in infants with high TSH levels (>20mIU/L). TSH and FT4 were estimated by Chemi Luminescence Immuno Assay (CLIA) method using reagent moonblind, INC. Result: Serum TSH of screened neonates ranged between 0.16mIU/L and 80.32mIU/L, Mean ± SD of sTSH being 5.80±3.96mIU/L. Out of 2212 screened newborns, 9 newborns had sTSH value >20mIU/L. out of 9 recalled newborns, 3 had persistently elevated sTSH >20mIU/L. Making incidence of Congenital hypothyroidism of 1:737 in our study. In a study carried out at Israel found 15.6% cases of Congenital Hypothyroidism were associated with congenital anomalies majority being cardiac anomalies. Conclusion: In our study we found a higher incidence of 1 in 737, when compared to estimated national incidence of congenital hypothyroidism. Our study reported significant number of neonates with sTSH value >10mIU/L indicating iodine deficiency prevalent in this part of country.
{"title":"Incidence of congenital hypothyroidism and associated congenital anomalies at VSS Medical College & Hospital, Burla","authors":"Vidhyadhara Naik Tl, S. K. Jena, N. Mishra","doi":"10.33545/26643685.2020.v3.i2c.111","DOIUrl":"https://doi.org/10.33545/26643685.2020.v3.i2c.111","url":null,"abstract":"Background: The worldwide incidence of CH ranges from 1 in 3000 to 1 in 4000 live newborn. However, varied incidence has been found from state, regional, and national screening programs. Objective: to know the incidence of Congenital Hypothyroidism and associated congenital anomalies in this part of the country, which is necessary to understand the burden of congenital hypothyroidism to the society. Setting: Primary serum TSH measurement in screening neonates with backup thyroxine (T 4 ) determination in infants with high TSH levels (>20mIU/L). TSH and FT4 were estimated by Chemi Luminescence Immuno Assay (CLIA) method using reagent moonblind, INC. Result: Serum TSH of screened neonates ranged between 0.16mIU/L and 80.32mIU/L, Mean ± SD of sTSH being 5.80±3.96mIU/L. Out of 2212 screened newborns, 9 newborns had sTSH value >20mIU/L. out of 9 recalled newborns, 3 had persistently elevated sTSH >20mIU/L. Making incidence of Congenital hypothyroidism of 1:737 in our study. In a study carried out at Israel found 15.6% cases of Congenital Hypothyroidism were associated with congenital anomalies majority being cardiac anomalies. Conclusion: In our study we found a higher incidence of 1 in 737, when compared to estimated national incidence of congenital hypothyroidism. Our study reported significant number of neonates with sTSH value >10mIU/L indicating iodine deficiency prevalent in this part of country.","PeriodicalId":144032,"journal":{"name":"International Journal of Paediatrics and Geriatrics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130949765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-01DOI: 10.33545/26643685.2020.v3.i2b.94
M. Deepan, R. PraveenKumar
Background: Seizure is one of the most common disorder in children and anti epileptics vary depending on the type of seizures occurring. Methods: In total 50 children of age between 1-12 years requiring anti epileptics for seizure are taken into consideration and compared. Seizure mimicking disorder were excluded from this study. Results: Among the 50 patients, valproate was predominantly used for generalized seizures followed by combination therapy of valproate and phenytoin followed by phenytoin and Levetiracetam. For focal sezuires, carbamazepine was used predominantly. Discussion: The initial evaluation based on history and examination for the type of seizures is important for pediatrician to assess the type of anti epileptic used. Conclusion: Valproate and phenytoin are mostly used for generalized type of seizures while carbamazepine is used for focal type of seizures.
{"title":"Relationship between antiepileptic medications and type of seizures","authors":"M. Deepan, R. PraveenKumar","doi":"10.33545/26643685.2020.v3.i2b.94","DOIUrl":"https://doi.org/10.33545/26643685.2020.v3.i2b.94","url":null,"abstract":"Background: Seizure is one of the most common disorder in children and anti epileptics vary depending on the type of seizures occurring. Methods: In total 50 children of age between 1-12 years requiring anti epileptics for seizure are taken into consideration and compared. Seizure mimicking disorder were excluded from this study. Results: Among the 50 patients, valproate was predominantly used for generalized seizures followed by combination therapy of valproate and phenytoin followed by phenytoin and Levetiracetam. For focal sezuires, carbamazepine was used predominantly. Discussion: The initial evaluation based on history and examination for the type of seizures is important for pediatrician to assess the type of anti epileptic used. Conclusion: Valproate and phenytoin are mostly used for generalized type of seizures while carbamazepine is used for focal type of seizures.","PeriodicalId":144032,"journal":{"name":"International Journal of Paediatrics and Geriatrics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113963397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-01DOI: 10.33545/26643685.2020.v3.i2b.103
Dr. N Sathyadith, Dr. M Sucindar, Dr. S Ramesh
Background: Mechanical ventilation refers to artificial methods used for supporting ventilation and oxygenation. With the advent of mechanical ventilation, the intensive care for pediatric patients have witnessed high success rates, better management of complications and improved outcomes with reduced mortality and morbidity rates. This study was done to assess the preceding risk factors, indication, clinical profile and outcome of mechanically ventilated children from rural population admitted in a tertiary care hospital. Methods: Prospective observational study of critically ill cchildren between 2 months and 12 years of age who required mechanical ventilation in Pediatric Intensive Care Unit of a tertiary care hospital. The data collected includes epidemiological profile, risk factors, clinical, laboratory and mechanical ventilation profile. Results: A total of 70 children required mechanical ventilation .The mean ± SD age of the participants was 2.05 ±2.4 years. Bronchopneumonia was the most common diagnosis (n=20, 28.6%) and the most common indication for mechanical ventilation among the study participants was severe respiratory distress (n=23, 32.9%).The most common complication observed among the study participants was Ventilator associated pneumonia (n=21, 30%). Overall, majority of the participants survived (n=44, 62.9%) while 26 (37.1%) participants expired in this study. Conclusion: Majority of the children were less than 1 year of age from poor socio economic status. Respiratory causes like bronchopneumonia and bronchiolitis were the common conditions requiring mechanical ventilation. More analytical studies are needed in future, to estimate the long term sequelae and outcome in mechanically ventilated children.
{"title":"Clinical profile and outcome of mechanically ventilated children in pediatric intensive care unit at a tertiary care hospital","authors":"Dr. N Sathyadith, Dr. M Sucindar, Dr. S Ramesh","doi":"10.33545/26643685.2020.v3.i2b.103","DOIUrl":"https://doi.org/10.33545/26643685.2020.v3.i2b.103","url":null,"abstract":"Background: Mechanical ventilation refers to artificial methods used for supporting ventilation and oxygenation. With the advent of mechanical ventilation, the intensive care for pediatric patients have witnessed high success rates, better management of complications and improved outcomes with reduced mortality and morbidity rates. This study was done to assess the preceding risk factors, indication, clinical profile and outcome of mechanically ventilated children from rural population admitted in a tertiary care hospital. Methods: Prospective observational study of critically ill cchildren between 2 months and 12 years of age who required mechanical ventilation in Pediatric Intensive Care Unit of a tertiary care hospital. The data collected includes epidemiological profile, risk factors, clinical, laboratory and mechanical ventilation profile. Results: A total of 70 children required mechanical ventilation .The mean ± SD age of the participants was 2.05 ±2.4 years. Bronchopneumonia was the most common diagnosis (n=20, 28.6%) and the most common indication for mechanical ventilation among the study participants was severe respiratory distress (n=23, 32.9%).The most common complication observed among the study participants was Ventilator associated pneumonia (n=21, 30%). Overall, majority of the participants survived (n=44, 62.9%) while 26 (37.1%) participants expired in this study. Conclusion: Majority of the children were less than 1 year of age from poor socio economic status. Respiratory causes like bronchopneumonia and bronchiolitis were the common conditions requiring mechanical ventilation. More analytical studies are needed in future, to estimate the long term sequelae and outcome in mechanically ventilated children.","PeriodicalId":144032,"journal":{"name":"International Journal of Paediatrics and Geriatrics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121427973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
There is limited data regarding the features of SARS-CoV-2 in children despite the worldwide spread. We aimed to elucidate a better understanding of the clinical and laboratory features of SARS-CoV-2 infection in children. Clinical data about presenting symptoms, exposure history, age, gender, presence of comorbidities, laboratory data, radiological findings including chest radiographs, modalities of treatment, need for hospitalization and clinical classification of disease severity, length of admission were extracted from the medical records. A total of 27 pediatric patients with COVID-19 were included in this study. There were 15 boys, 55.5%. The mean age of children was 6.3 years (range= 2 months-17 years). Six children were hospitalized (22.2%), Hematological abnormalities were present in 15 out of 27 (55.5%) children. All patients got CXRs and 7 out of 27 had abnormal findings (25.9%). There may be differences in presenting symptoms and clinical features between children from different regions and countries. This pediatric clinical report adds data from the epicenter of pandemic in Turkey, Istanbul, discussing symptomatology and radiological findings in children.
{"title":"Evaluation of clinical and laboratory findings of pediatric COVID-19: A single-center experience","authors":"Nihan Uygur Klc, Ozlem Erdede, Erdal Sar, Rabia Gnl Sezer Yamanel","doi":"10.33545/26643685.2020.v3.i2b.100","DOIUrl":"https://doi.org/10.33545/26643685.2020.v3.i2b.100","url":null,"abstract":"There is limited data regarding the features of SARS-CoV-2 in children despite the worldwide spread. We aimed to elucidate a better understanding of the clinical and laboratory features of SARS-CoV-2 infection in children. Clinical data about presenting symptoms, exposure history, age, gender, presence of comorbidities, laboratory data, radiological findings including chest radiographs, modalities of treatment, need for hospitalization and clinical classification of disease severity, length of admission were extracted from the medical records. A total of 27 pediatric patients with COVID-19 were included in this study. There were 15 boys, 55.5%. The mean age of children was 6.3 years (range= 2 months-17 years). Six children were hospitalized (22.2%), Hematological abnormalities were present in 15 out of 27 (55.5%) children. All patients got CXRs and 7 out of 27 had abnormal findings (25.9%). There may be differences in presenting symptoms and clinical features between children from different regions and countries. This pediatric clinical report adds data from the epicenter of pandemic in Turkey, Istanbul, discussing symptomatology and radiological findings in children.","PeriodicalId":144032,"journal":{"name":"International Journal of Paediatrics and Geriatrics","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127498374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-01DOI: 10.33545/26643685.2020.v3.i2c.203
Dr. N Ram Charana Reddy
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