Pub Date : 2021-01-01DOI: 10.22271/27069567.2021.V3.I1C.115
S. Ahamed, Adrama
Several studies undertaken have been unable to link ABO blood groups to the incidence of malaria and related clinical outcome. There is a paucity of hospital based, comparative studies to investigate the relationship between blood groups types and severity of malarial infections. Several studies undertaken have been unable to link ABO blood groups to the incidence of malaria and related clinical outcome. There is a paucity of hospital based, comparative studies to investigate the relationship between blood groups types and severity of malarial infections.
{"title":"A Study of blood group protection to severe malarial complication in children","authors":"S. Ahamed, Adrama","doi":"10.22271/27069567.2021.V3.I1C.115","DOIUrl":"https://doi.org/10.22271/27069567.2021.V3.I1C.115","url":null,"abstract":"Several studies undertaken have been unable to link ABO blood groups to the incidence of malaria and related clinical outcome. There is a paucity of hospital based, comparative studies to investigate the relationship between blood groups types and severity of malarial infections. Several studies undertaken have been unable to link ABO blood groups to the incidence of malaria and related clinical outcome. There is a paucity of hospital based, comparative studies to investigate the relationship between blood groups types and severity of malarial infections.","PeriodicalId":144032,"journal":{"name":"International Journal of Paediatrics and Geriatrics","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115543023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.33545/26643685.2021.v4.i1a.128
Rakesh Balamkar, A. Sajjan, S. Byakod, S. Kalyanshettar
Background: To study the occurrence of hypocalcaemia in neonates with physiological unconjugated hyperbilirubinemia after 48 hours of phototherapy or at the end of phototherapy, in case duration of phototherapy was less than 48 hours. Methods: This prospective study was conducted on 100 term neonates (61 males and 39 females) admitted to Neonatal intensive care unit of Shri B M Patil Medical College and Hospital, Vijayapura, Karnataka with unconjugated hyperbilirubinemia and requiring phototherapy. Total Serum bilirubin levels and serum calcium levels were checked before and after phototherapy. Neonates were assessed for clinical features of hypocalcemia i.e. jitteriness, irritability/excitability, lethargy and convulsions. Results: After phototherapy, there was hypocalcemia in 35.0% neonates. The difference between pre and post phototherapy serum calcium levels were found to be statistically significant (p <0.001). 2.86% of neonates developed jitteriness among those who had hypocalcemia. Hypocalcemia was more in subjects who received phototherapy for longer duration. Conclusions: Hypocalcaemia is a common complication of phototherapy. Therefore, calcium supplementation should be done in all neonates undergoing phototherapy.
背景:研究生理性非共轭高胆红素血症新生儿在光疗后48小时或光疗结束时(光疗时间小于48小时)低钙血症的发生情况。方法:对卡纳塔克邦Vijayapura Shri B M Patil医学院和医院新生儿重症监护室收治的100例非偶联性高胆红素血症并需要光疗的足月新生儿(男61例，女39例)进行前瞻性研究。检测光疗前后血清总胆红素水平和血清钙水平。评估新生儿低钙血症的临床特征，即神经质、易怒/兴奋性、嗜睡和惊厥。结果:光疗后新生儿低钙发生率为35.0%。光疗前后血清钙水平差异有统计学意义(p <0.001)。低钙血症的新生儿中有2.86%出现神经过敏。低钙血症在接受较长时间光疗的受试者中较多。结论:低钙血症是光疗的常见并发症。因此，所有接受光疗的新生儿都应补充钙。
{"title":"Effect of phototherapy on serum calcium levels in neonates receiving double surface LED phototherapy for neonatal jaundice","authors":"Rakesh Balamkar, A. Sajjan, S. Byakod, S. Kalyanshettar","doi":"10.33545/26643685.2021.v4.i1a.128","DOIUrl":"https://doi.org/10.33545/26643685.2021.v4.i1a.128","url":null,"abstract":"Background: To study the occurrence of hypocalcaemia in neonates with physiological unconjugated hyperbilirubinemia after 48 hours of phototherapy or at the end of phototherapy, in case duration of phototherapy was less than 48 hours. Methods: This prospective study was conducted on 100 term neonates (61 males and 39 females) admitted to Neonatal intensive care unit of Shri B M Patil Medical College and Hospital, Vijayapura, Karnataka with unconjugated hyperbilirubinemia and requiring phototherapy. Total Serum bilirubin levels and serum calcium levels were checked before and after phototherapy. Neonates were assessed for clinical features of hypocalcemia i.e. jitteriness, irritability/excitability, lethargy and convulsions. Results: After phototherapy, there was hypocalcemia in 35.0% neonates. The difference between pre and post phototherapy serum calcium levels were found to be statistically significant (p <0.001). 2.86% of neonates developed jitteriness among those who had hypocalcemia. Hypocalcemia was more in subjects who received phototherapy for longer duration. Conclusions: Hypocalcaemia is a common complication of phototherapy. Therefore, calcium supplementation should be done in all neonates undergoing phototherapy.","PeriodicalId":144032,"journal":{"name":"International Journal of Paediatrics and Geriatrics","volume":"139 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124559466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.33545/26643685.2021.v4.i1b.139
Shramana Ray, Asha P. Shetty
Background: When children and young people present to healthcare environments, they are faced with a range of emotions, from fear to anxiety, all which are potentially exacerbated by unfamiliar surroundings, people and equipment. Age appropriate communication to the child during any procedure can make the child understand at their level about the procedure. The study aimed to assess the procedural communication techniques nurses uses during painful procedure of children in Paediatric ward of Aims, BBBSR. Method: The observational study was done on 60 events of blood sampling and intravenous cannulation among children in Paediatric Ward of AIIMS, BBSR using a Checklist for Paediatric Procedural communication. Purposive sampling technique was used. Result: Among all participant nurses 55 (91.6%) explained the procedure to the children before doing, 45 (75%) nurses avoided negative words during the procedure. 55 (91.6%) nurses gave choices and empower. 40 (66.6%) nurses allowed children’s independence and 15 (25%) nurses allowed to play and get familiar with certain equipment. Maximum nurses 50(83.3%) were used of distractor along with communication. Conclusion: Majority of the nurses used age specific communication techniques during procedures with the children.
{"title":"Assess the procedural communication techniques nurses uses during painful procedure of children in paediatric ward","authors":"Shramana Ray, Asha P. Shetty","doi":"10.33545/26643685.2021.v4.i1b.139","DOIUrl":"https://doi.org/10.33545/26643685.2021.v4.i1b.139","url":null,"abstract":"Background: When children and young people present to healthcare environments, they are faced with a range of emotions, from fear to anxiety, all which are potentially exacerbated by unfamiliar surroundings, people and equipment. Age appropriate communication to the child during any procedure can make the child understand at their level about the procedure. The study aimed to assess the procedural communication techniques nurses uses during painful procedure of children in Paediatric ward of Aims, BBBSR. Method: The observational study was done on 60 events of blood sampling and intravenous cannulation among children in Paediatric Ward of AIIMS, BBSR using a Checklist for Paediatric Procedural communication. Purposive sampling technique was used. Result: Among all participant nurses 55 (91.6%) explained the procedure to the children before doing, 45 (75%) nurses avoided negative words during the procedure. 55 (91.6%) nurses gave choices and empower. 40 (66.6%) nurses allowed children’s independence and 15 (25%) nurses allowed to play and get familiar with certain equipment. Maximum nurses 50(83.3%) were used of distractor along with communication. Conclusion: Majority of the nurses used age specific communication techniques during procedures with the children.","PeriodicalId":144032,"journal":{"name":"International Journal of Paediatrics and Geriatrics","volume":"73 8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128036116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.33545/26643685.2021.v4.i1c.146
Dr. Hashiq N, Dr. Ramesh Nigade, Dr. Amith K, D. A. B. Kurane
COVID-19 associated MIS-C like the disease has not been well described in neonates. So this study aimed to alert the neonatal community to the possibility of the multisystem inflammatory syndrome in children (MIS-C) like disease in critically ill neonates born to mothers with or without a history of SARS-CoV-2 infection or exposure. It’s a retrospective study of four neonatal cases admitted in Dr. DY Patil Medical College NICU. All four cases are from different localities with sharing of common antepartum, intrapartum and postpartum period. All are preterm with meconium aspiration syndrome. All are presented on day three of life with dark red color vomiting and respiratory distress. All Babies were normal initial three days. Early treatment with IVIG and surfactant were showed rapid clinical improvement in all four cases. SARS-CoV-2 associated MIS-C like the disease has not been well described in neonates. Even though WHO defined criteria for MIS-N, that typical features may be conspicuously absent. Therefore a high index of suspicion is warranted in critically ill neonates who presented after a period of normality about three days with the above symptoms.
与COVID-19相关的misc样疾病在新生儿中尚未得到很好的描述。因此，本研究旨在提醒新生儿界，有或没有SARS-CoV-2感染或暴露史的母亲所生的危重新生儿可能发生儿童多系统炎症综合征(MIS-C)样疾病。这是对Dr. DY Patil医学院新生儿重症监护室收治的4例新生儿病例的回顾性研究。4例患者均来自不同地区，产前、产中、产后时间相同。都是早产胎粪吸入综合征。所有患者均在出生第三天出现深红色呕吐和呼吸窘迫。所有的婴儿在最初的三天都很正常。早期应用IVIG和表面活性剂治疗均能迅速改善临床症状。SARS-CoV-2相关的misc样疾病在新生儿中尚未得到很好的描述。尽管世卫组织为MIS-N定义了标准，但这些典型特征可能明显缺失。因此，对于在一段正常时间后出现上述症状约三天的危重新生儿，应高度怀疑。
{"title":"Multisystem inflammatory syndrome in a neonate, temporally associated with prenatal exposure to SARS-COV-2: Case series","authors":"Dr. Hashiq N, Dr. Ramesh Nigade, Dr. Amith K, D. A. B. Kurane","doi":"10.33545/26643685.2021.v4.i1c.146","DOIUrl":"https://doi.org/10.33545/26643685.2021.v4.i1c.146","url":null,"abstract":"COVID-19 associated MIS-C like the disease has not been well described in neonates. So this study aimed to alert the neonatal community to the possibility of the multisystem inflammatory syndrome in children (MIS-C) like disease in critically ill neonates born to mothers with or without a history of SARS-CoV-2 infection or exposure. It’s a retrospective study of four neonatal cases admitted in Dr. DY Patil Medical College NICU. All four cases are from different localities with sharing of common antepartum, intrapartum and postpartum period. All are preterm with meconium aspiration syndrome. All are presented on day three of life with dark red color vomiting and respiratory distress. All Babies were normal initial three days. Early treatment with IVIG and surfactant were showed rapid clinical improvement in all four cases. SARS-CoV-2 associated MIS-C like the disease has not been well described in neonates. Even though WHO defined criteria for MIS-N, that typical features may be conspicuously absent. Therefore a high index of suspicion is warranted in critically ill neonates who presented after a period of normality about three days with the above symptoms.","PeriodicalId":144032,"journal":{"name":"International Journal of Paediatrics and Geriatrics","volume":"112 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131860106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.33545/26643685.2021.v4.i1c.145
Sofia Ferrito, Rita Marques, Maria Cabral, F. Nunes, Margarida Pinto
Introduction: Extra-pulmonary manifestations of tuberculosis occur in about 20% of cases. Peritoneal and genital tuberculosis are uncommon, especially in children without any comorbidity. Case report: A previously healthy 14-year-old girl, presented complaints of weight loss, anorexia, abdominal pain and fever. On examination, she was febrile, with rebound abdominal tenderness and abdominal distension. Ultrasonography reported peritoneal fluid, fibrin strands and complex cystic lesions in the adnexal region. Laparotomy evidenced multiple peritoneal cysts, purulent exudate with bilateral pyosalpinx. Mycobacterium tuberculosis was isolated in culture and confirmed the diagnosis of Peritoneal Tuberculosis. Antituberculous quadruple therapy and corticosteroids were started, with good clinical response. Conclusions: Peritoneal and genital tuberculosis are uncommon in children, but have high fatality and infertility rate. Due to the nonspecific clinical, laboratory or radiology findings, diagnosis is often delayed. This report highlights the need for a big suspicious index of the disease for an accurate and early diagnosis.
{"title":"Peritoneal and genital tuberculosis in an adolescent: A challenging diagnosis","authors":"Sofia Ferrito, Rita Marques, Maria Cabral, F. Nunes, Margarida Pinto","doi":"10.33545/26643685.2021.v4.i1c.145","DOIUrl":"https://doi.org/10.33545/26643685.2021.v4.i1c.145","url":null,"abstract":"Introduction: Extra-pulmonary manifestations of tuberculosis occur in about 20% of cases. Peritoneal and genital tuberculosis are uncommon, especially in children without any comorbidity. Case report: A previously healthy 14-year-old girl, presented complaints of weight loss, anorexia, abdominal pain and fever. On examination, she was febrile, with rebound abdominal tenderness and abdominal distension. Ultrasonography reported peritoneal fluid, fibrin strands and complex cystic lesions in the adnexal region. Laparotomy evidenced multiple peritoneal cysts, purulent exudate with bilateral pyosalpinx. Mycobacterium tuberculosis was isolated in culture and confirmed the diagnosis of Peritoneal Tuberculosis. Antituberculous quadruple therapy and corticosteroids were started, with good clinical response. Conclusions: Peritoneal and genital tuberculosis are uncommon in children, but have high fatality and infertility rate. Due to the nonspecific clinical, laboratory or radiology findings, diagnosis is often delayed. This report highlights the need for a big suspicious index of the disease for an accurate and early diagnosis.","PeriodicalId":144032,"journal":{"name":"International Journal of Paediatrics and Geriatrics","volume":"98 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126822866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.33545/26643685.2021.v4.i1b.135
Amit Vatkar, Nisha Dolas, K. Kanmani, Vijay Kamale
ASXL3 mutations were first identified in 2013 by Bainbridge et al . as a cause of syndromic intellectual disability in four children with similar phenotypes using whole-exome sequencing. The clinical features – postulated by Bainbridge et al . were developmental delay, severe feeding difficulties, failure to thrive and neurological abnormalities. To date, a total of nine individuals with BRPS have been published in the literature in four reports (Bainbridge et al ., Dinwiddie et al , Srivastava et al . and Hori et al .). In this report, we describe an uncertain variant present in Exon 11 of ASXL3(+) heterozygous zygosity in a female child with clinical features: truncal muscular hypotonia with significant motor delay, profound speech impairment, intellectual disability and a characteristic dysmorphic facies phenotype (open mouth, full lips, depressed nasal bridge, metopic prominence, microcephaly (45.5.cm), with camptodactyly and dysplastic fingers). Hence, we are reporting a rare case of developmental delay.
{"title":"Bainbridge-Roper syndrome: A rare case of developmental delay","authors":"Amit Vatkar, Nisha Dolas, K. Kanmani, Vijay Kamale","doi":"10.33545/26643685.2021.v4.i1b.135","DOIUrl":"https://doi.org/10.33545/26643685.2021.v4.i1b.135","url":null,"abstract":"ASXL3 mutations were first identified in 2013 by Bainbridge et al . as a cause of syndromic intellectual disability in four children with similar phenotypes using whole-exome sequencing. The clinical features – postulated by Bainbridge et al . were developmental delay, severe feeding difficulties, failure to thrive and neurological abnormalities. To date, a total of nine individuals with BRPS have been published in the literature in four reports (Bainbridge et al ., Dinwiddie et al , Srivastava et al . and Hori et al .). In this report, we describe an uncertain variant present in Exon 11 of ASXL3(+) heterozygous zygosity in a female child with clinical features: truncal muscular hypotonia with significant motor delay, profound speech impairment, intellectual disability and a characteristic dysmorphic facies phenotype (open mouth, full lips, depressed nasal bridge, metopic prominence, microcephaly (45.5.cm), with camptodactyly and dysplastic fingers). Hence, we are reporting a rare case of developmental delay.","PeriodicalId":144032,"journal":{"name":"International Journal of Paediatrics and Geriatrics","volume":"42 19","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113936086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.33545/26643685.2021.v4.i1c.162
T. Islam, N. Bhat, Eijaz Ahmad Shah, M. Sheikh
{"title":"Accuracy of pediatric risk of mortality (PRISM) III score in predicting mortality outcomes in a pediatric intensive care unit in Srinagar","authors":"T. Islam, N. Bhat, Eijaz Ahmad Shah, M. Sheikh","doi":"10.33545/26643685.2021.v4.i1c.162","DOIUrl":"https://doi.org/10.33545/26643685.2021.v4.i1c.162","url":null,"abstract":"","PeriodicalId":144032,"journal":{"name":"International Journal of Paediatrics and Geriatrics","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131133493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.33545/26643685.2021.V4.I1B.138
G. Parvez, Chowdhury Abdullah Us Shams Tilak, Parmita Zaman
Background: Antenatal Care and Postnatal Care are one of the major components of safe motherhood to prevent maternal and neonatal mortality and to lead healthy and safe outcome of pregnancy. This cross sectional study was conducted on factors associated with Antenatal Care and Postnatal Care coverage among married women.Methodology: This cross-sectional study was undertaken in Gaibandha district on 320 married women with at least one children of age under 1 year age was taken.Results: Most of the women (56%) under this study was married before 18 years age. About 37.50% women have two ANC visit and 21.88% has 3 ANC visit and 25% have 1 ANC visit. Only 6.25% women fulfills sufficient ANC visit (4 times). At least one PNC service receiving rate is 59.38%, at least two PNC visit was 18.75% and No PNC visit was 15.62%.Conclusion: Most of the pregnant women were reluctant on ANC and PNC visit.
{"title":"Utilization of ANC/PNC by the care receivers from community clinic and associated factors of the catchment area Gaibandha district","authors":"G. Parvez, Chowdhury Abdullah Us Shams Tilak, Parmita Zaman","doi":"10.33545/26643685.2021.V4.I1B.138","DOIUrl":"https://doi.org/10.33545/26643685.2021.V4.I1B.138","url":null,"abstract":"Background: Antenatal Care and Postnatal Care are one of the major components of safe motherhood to prevent maternal and neonatal mortality and to lead healthy and safe outcome of pregnancy. This cross sectional study was conducted on factors associated with Antenatal Care and Postnatal Care coverage among married women.Methodology: This cross-sectional study was undertaken in Gaibandha district on 320 married women with at least one children of age under 1 year age was taken.Results: Most of the women (56%) under this study was married before 18 years age. About 37.50% women have two ANC visit and 21.88% has 3 ANC visit and 25% have 1 ANC visit. Only 6.25% women fulfills sufficient ANC visit (4 times). At least one PNC service receiving rate is 59.38%, at least two PNC visit was 18.75% and No PNC visit was 15.62%.Conclusion: Most of the pregnant women were reluctant on ANC and PNC visit.","PeriodicalId":144032,"journal":{"name":"International Journal of Paediatrics and Geriatrics","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125103250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.33545/26643685.2021.v4.i1b.129
Devendiran A, R. R., Manohar U
Background and Objectives: Meconium stained Liquor is an alarming perinatal condition of the foetus which is associated with high rates of perinatal mortality. Nucleated red blood cells (NRBCs) are released from the foetal bone marrow in response to increased erythropoietin situations of hypoxia. The objectives of the study were to compare the level of nucleated red blood cells between neonates born with meconium stained amniotic fluid (cases) and clear amniotic fluid (controls) and to find out the association between nucleated red blood cells level and poor outcomes among neonates with meconium stained amniotic fluid. Materials and Methods: The study was case control study conducted in neonatology unit of paediatrics department among 50 neonates with meconium stained amniotic fluid as cases and 50 neonates with clear amniotic fluid as controls for a period of 2 years. Informed consent was obtained from each study participant. The data was collected using a pretested semi structured interview schedule and NRBCs level were estimated using 2 ml umbilical cord blood collected from each study participant. The data collected was entered into excel sheet and analysed using SPSS version 23. Results: The NRBCs among the cases was found to be more than among the controls and the difference was statistically significant. The mean NRBCs level were found to be more among those with poor Cry/Suck/Activity. The mean NRBCs level among those who had received oxygen support was more than those who had not received any. Similarly, among those who expired the mean NRBCs level was more. Conclusion: To conclude increased NRBCs level among the neonates with meconium stained amniotic fluid could indicate poor outcome. .
背景与目的:胎粪染色液是一种令人担忧的胎儿围产期疾病，它与围产期死亡率高有关。有核红细胞(nrbc)从胎儿骨髓中释放，以应对缺氧情况下红细胞生成素的增加。本研究的目的是比较胎粪染色羊水新生儿(病例)和正常羊水新生儿(对照组)的有核红细胞水平，并找出胎粪染色羊水新生儿有核红细胞水平与不良结局之间的关系。材料与方法:在儿科新生儿科进行病例对照研究，以羊水胎粪染色的新生儿50例为病例，羊水清澈的新生儿50例为对照，为期2年。每位研究参与者都获得了知情同意。数据采用预先测试的半结构化访谈计划收集，并使用从每位研究参与者收集的2ml脐带血估计nrbc水平。将收集到的数据输入到excel表格中，并使用SPSS version 23进行分析。结果:两组患者nrbc均高于对照组，差异有统计学意义。在哭泣/吮吸/活动较差的人群中，平均nrbc水平更高。接受氧支持组的平均nrbc水平高于未接受氧支持组。同样，在那些死亡的患者中，平均nrbc水平更高。结论:羊水胎粪染色新生儿nrbc水平升高提示预后不良。
{"title":"Assay of nucleated red blood cells in the umbilical cord blood to assess the severity of outcome among the neonates born with meconium stained amniotic fluid","authors":"Devendiran A, R. R., Manohar U","doi":"10.33545/26643685.2021.v4.i1b.129","DOIUrl":"https://doi.org/10.33545/26643685.2021.v4.i1b.129","url":null,"abstract":"Background and Objectives: Meconium stained Liquor is an alarming perinatal condition of the foetus which is associated with high rates of perinatal mortality. Nucleated red blood cells (NRBCs) are released from the foetal bone marrow in response to increased erythropoietin situations of hypoxia. The objectives of the study were to compare the level of nucleated red blood cells between neonates born with meconium stained amniotic fluid (cases) and clear amniotic fluid (controls) and to find out the association between nucleated red blood cells level and poor outcomes among neonates with meconium stained amniotic fluid. Materials and Methods: The study was case control study conducted in neonatology unit of paediatrics department among 50 neonates with meconium stained amniotic fluid as cases and 50 neonates with clear amniotic fluid as controls for a period of 2 years. Informed consent was obtained from each study participant. The data was collected using a pretested semi structured interview schedule and NRBCs level were estimated using 2 ml umbilical cord blood collected from each study participant. The data collected was entered into excel sheet and analysed using SPSS version 23. Results: The NRBCs among the cases was found to be more than among the controls and the difference was statistically significant. The mean NRBCs level were found to be more among those with poor Cry/Suck/Activity. The mean NRBCs level among those who had received oxygen support was more than those who had not received any. Similarly, among those who expired the mean NRBCs level was more. Conclusion: To conclude increased NRBCs level among the neonates with meconium stained amniotic fluid could indicate poor outcome. .","PeriodicalId":144032,"journal":{"name":"International Journal of Paediatrics and Geriatrics","volume":"332 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123326982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.33545/26643685.2021.V4.I1B.137
Manchu Polayya
Background & Objectives: Anemia is common among children in developing countries. In the National Family Health Survey III of India, 70% of children were anemic. In India 81% of infants between 6 and 9 months of age become anemic most due to iron deficiency. In term infants, a brief delay in clamping the umbilical cord after birth results in higher concentrations of hemoglobin (HB) and hematocrit during the neonatal period, increased serum ferritin levels and a lower incidence of iron-deficiency anemia at 4-6 months of age. This study is conducted to compare the effect of delayed cord clamping or umbilical cord milking to early cord clamping on neonatal hematological status at 48 hours of age in term neonates born in GEMS and Hospital, Ragolu, Srikakulam.Materials and methods: The study was conducted in the labor room, obstetrics operation theatre and post natal ward of GEMS and Hospital, Ragolu, Srikakulam during November 2019 to May 2021. The newborn babies were divided into 3 groups of each 55.Group 1: Early cord clamping at 30 sec after birthGroup 2: Delayed cord clamping at 60 sec after birth.Group 3: Cord milking in 10-15 sec after birth.- In our hospital cord clamping is done as early as possible, within 30 sec.- In this study delayed cord clamping was done at 60 sec after birth because maximum placental transfusion, up to 50-75%, occurs by 1min after birth.- Cord milking was done by milking of the unclamped cord towards the umbilicus 4 times in 10-15 seconds followed by clamping and cutting of the cord.All the newborn babies received the same care. At 48hours of age the hemoglobin levels were tested.Results: Total of 165 term babies were included in the study, divided into three groups (early cord clamping, delayed cord clamping and cord milking).There were 55 babies in each group. The mean haemoglobin at 48 hours of life was 17.192±1.86 g/dl in the early cord clamping group, 19.623±1.45 g/dl in the delayed cord clamping group and 19.635±1.45 g/dl in the cord milking group. Milking the umbilical cord four times before clamping and cutting the cord or Delayed clamping of the cord by 60 seconds after delivery showed higher mean haemoglobin levels at 48 hours of life compared to early clamping.Conclusions: We conclude that both delayed cord clamping and cord milking resulted in significantly higher neonatal hemoglobin at 48 hours of life as compared to early clamping with no adverse outcomes.
{"title":"Comparison of early umbilical cord clamping v/s delayed cord clamping v/s cord milking on neonatal hemoglobin status - A randomized control study","authors":"Manchu Polayya","doi":"10.33545/26643685.2021.V4.I1B.137","DOIUrl":"https://doi.org/10.33545/26643685.2021.V4.I1B.137","url":null,"abstract":"Background & Objectives: Anemia is common among children in developing countries. In the National Family Health Survey III of India, 70% of children were anemic. In India 81% of infants between 6 and 9 months of age become anemic most due to iron deficiency. In term infants, a brief delay in clamping the umbilical cord after birth results in higher concentrations of hemoglobin (HB) and hematocrit during the neonatal period, increased serum ferritin levels and a lower incidence of iron-deficiency anemia at 4-6 months of age. This study is conducted to compare the effect of delayed cord clamping or umbilical cord milking to early cord clamping on neonatal hematological status at 48 hours of age in term neonates born in GEMS and Hospital, Ragolu, Srikakulam.Materials and methods: The study was conducted in the labor room, obstetrics operation theatre and post natal ward of GEMS and Hospital, Ragolu, Srikakulam during November 2019 to May 2021. The newborn babies were divided into 3 groups of each 55.Group 1: Early cord clamping at 30 sec after birthGroup 2: Delayed cord clamping at 60 sec after birth.Group 3: Cord milking in 10-15 sec after birth.- In our hospital cord clamping is done as early as possible, within 30 sec.- In this study delayed cord clamping was done at 60 sec after birth because maximum placental transfusion, up to 50-75%, occurs by 1min after birth.- Cord milking was done by milking of the unclamped cord towards the umbilicus 4 times in 10-15 seconds followed by clamping and cutting of the cord.All the newborn babies received the same care. At 48hours of age the hemoglobin levels were tested.Results: Total of 165 term babies were included in the study, divided into three groups (early cord clamping, delayed cord clamping and cord milking).There were 55 babies in each group. The mean haemoglobin at 48 hours of life was 17.192±1.86 g/dl in the early cord clamping group, 19.623±1.45 g/dl in the delayed cord clamping group and 19.635±1.45 g/dl in the cord milking group. Milking the umbilical cord four times before clamping and cutting the cord or Delayed clamping of the cord by 60 seconds after delivery showed higher mean haemoglobin levels at 48 hours of life compared to early clamping.Conclusions: We conclude that both delayed cord clamping and cord milking resulted in significantly higher neonatal hemoglobin at 48 hours of life as compared to early clamping with no adverse outcomes.","PeriodicalId":144032,"journal":{"name":"International Journal of Paediatrics and Geriatrics","volume":"442 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131572374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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