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Bilateral ptosis with ophthalmoplegia externa in paediatric onset multiple sclerosis: A case report 小儿多发性硬化症双侧上睑下垂伴外眼麻痹1例
Pub Date : 2023-02-15 DOI: 10.18231/j.ijooo.2022.061
Dheerendra Singh, Manisha Singh
Paediatric onset multiple sclerosis (POMS) patients usually present with a diminution of vision pertaining to optic neuritis and experience a more aggressive disease onset with disabling clinical symptoms, a polyfocal presentation at disease onset, and a higher relapse rate early in the disease course. We are reporting a unique presentation of bilateral ptosis with external ophthalmoplegia in a patient of a 17-year-old female patient who came with chief complaint of drooping of lids in both eyes for 3 years. Complete ophthalmic and systemic examination was done. Patient was diagnosed as MS according to the revised Mcdonald criteria and was given Methylprednisolone Pulse therapy. We concluded that acquired bilateral ptosis with ophthalmoplegia externa should be given special attention to rule out systemic associations. Timely diagnosis and early management of multiple sclerosis in the pediatric age group with DMT may reduce relapse frequency and functional disability.
小儿发作性多发性硬化症(POMS)患者通常表现为视神经炎引起的视力下降,并伴有更严重的疾病发作,伴有致残性临床症状,发病时为多灶性表现,并且在病程早期复发率较高。我们报告一个独特的双侧上睑下垂并外眼肌麻痹的患者,一位17岁的女性患者,主诉为双眼眼睑下垂3年。进行了全面的眼科和全身检查。根据修订后的Mcdonald标准诊断为MS,给予甲强的松龙脉冲治疗。我们的结论是,获得性双侧上睑下垂合并外眼肌麻痹应给予特别注意,以排除全身关联。及时诊断和早期管理多发性硬化症的儿童年龄组DMT可能会减少复发率和功能残疾。
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引用次数: 0
Diagnosis of dry eye patients with ocular irritation 干眼症患者眼部刺激的诊断
Pub Date : 2023-02-15 DOI: 10.18231/j.ijooo.2022.057
K. Kalaivani
Dry eye is often an under diagnosed condition of the eye that can cause discomfort, burning sensation and blurred vision. These symptoms are related to the alterations in the layers of tear film, insufficient production or excessive evaporation of tear film. The primary aim of this study is to diagnose and to find out the incidence of dry eye in patients presenting with symptoms of ocular irritation. A total number of 225 patients of both sexes aged between 20 and 80 years with complaints of ocular irritation were included in this study. Detailed history taking, slit lamp examination of the anterior segment, tear film breakup time (TBUT), Schirmer’s test, Fluorescein stain score and Rose Bengal stain score was done for all patients. Data was presented only for the worst eye of each patient. Dry eye was found in 46.67% of patients. Among symptomatic patients, 24% had TBUT value < 10 sec. Fluorescein score was ≥ 1 in 6.6% of symptomatic patients. RB score ≥3 was found in 28.4%. Both Schirmer test and TBUT were positive in 22.7% of the symptomatic patients. Only 4.9% of symptomatic patients were positive for all 3 tests including staining. This study firmly concludes that the Schirmer’s test, TBUT and staining should be done routinely for patients with ocular irritation for the early diagnosis of dry eye.
干眼症通常是一种未确诊的眼部疾病,可引起不适、灼烧感和视力模糊。这些症状与泪膜层的改变、泪膜分泌不足或过度蒸发有关。本研究的主要目的是诊断和发现出现眼部刺激症状的患者干眼的发生率。本研究共纳入225例年龄在20 ~ 80岁的男女患者,均有眼部刺激症状。对所有患者进行详细的病史记录、裂隙灯检查、泪膜破裂时间(TBUT)、Schirmer试验、荧光素染色评分和Rose Bengal染色评分。只提供了每位患者最差的眼睛的数据。46.67%的患者出现干眼症。有症状患者中TBUT值< 10秒的占24%,有症状患者中荧光素评分≥1的占6.6%。RB评分≥3分的占28.4%。22.7%的有症状患者Schirmer试验和TBUT均阳性。只有4.9%的有症状患者3项检测均阳性,包括染色。本研究明确认为,对于有眼部刺激的患者,应常规进行Schirmer试验、TBUT和染色,以早期诊断干眼。
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引用次数: 0
Optical biopsy – Optical coherence tomography guided excision of ocular surface squamous neoplasia 光学活检。光学相干断层扫描引导下的眼表鳞状瘤状病变切除术
Pub Date : 2023-02-15 DOI: 10.18231/j.ijooo.2022.053
D. Kumar, Amar
: To report the role of optical biopsy where the preoperative spectral domain optical coherence tomography (SD OCT) features were used for surgical margin clearance in ocular surface squamous neoplasia (OSSN) excision.In this prospectiveinterventional studypatients with clinically diagnosed OSSNundergopreoperative SD OCT and mass was excised with 3mm clearance with respect to the extent on OCT. Corneal, conjunctival margins and lamellar sclera was evaluated histopathologically. Twelve eyes of 11 patients with mean age of 59.2 ± 12.2 were studied. Hyper reflective epithelium, increased thickness, abrupt transition of corneal epithelium and increase back shadow were the features of OSSN noted. The mean functional epithelial thickness and epithelial thickness were 137.5± 60.6µm and 58.5±10.8 µm respectively. The histopathology confirmed as squamous cell carcinoma (SCC) (n=4, 33.3%), carcinoma in situ (CIN) (n=8, 66.6%). In CIN 2 eyes were severe dysplasia and 6 were moderate dysplasia. Corneal clearance was noted as 100 %. Of 36 conjunctival margins, the positive margin noted in 6 eyes (50%). Nasal margin (n=3) and temporal (n=3) were the common margins. There was no difference in clearance between CIN (50%) or SCC (50%) on conjunctival side. Two eyes with recurrence required and revision excision subsequent topical chemotherapyOptical biopsy by SD OCT though is an effective method for OSSN removal. Corneal margins showed better margin clearance than conjunctival.
目的:报道术前光谱域光学相干断层扫描(SD OCT)特征用于眼表鳞状瘤状病变(OSSN)切除手术边缘清除的光学活检的作用。在这项前瞻性的介入研究中,临床诊断为osss的患者在手术后的SD OCT下切除肿块,并在OCT上切除3mm间隙,角膜,结膜边缘和板层巩膜进行组织病理学评估。11例患者共12只眼,平均年龄59.2±12.2岁。高反射性上皮,厚度增加,角膜上皮突变,背阴增加是OSSN的特征。平均功能上皮厚度和上皮厚度分别为137.5±60.6µm和58.5±10.8µm。组织病理学证实为鳞状细胞癌(SCC) (n=4, 33.3%),原位癌(CIN) (n=8, 66.6%)。CIN 2眼重度发育不良,6眼中度发育不良。角膜清除率为100%。36眼结膜边缘,阳性边缘6眼(50%)。鼻缘(n=3)和颞缘(n=3)为常见缘。结膜侧CIN(50%)和SCC(50%)的清除率无差异。双眼复发,局部化疗后进行翻修切除,但SD OCT光学活检是去除OSSN的有效方法。角膜边缘比结膜边缘清除率高。
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引用次数: 0
Accuracy in clinical diagnosis of benign peri-ocular mass lesions 良性眼周肿块的临床诊断准确性
Pub Date : 2023-02-15 DOI: 10.18231/j.ijooo.2022.054
Shrithi Das Shetty, S. P
To analyze accuracy in clinical diagnosis of peri-ocular benign lesions. A prospective, interventional study of 279 clinically diagnosed and or histo-pathologically confirmed eyelid mass lesions. At presentation, detailed demographic data, symptoms, duration since the mass noted, it’s location, size & physical appearance, progression/regression/recurrence of the lid mass if any and associated systemic ailments were noted. Then, a pre-treatment clinical diagnosis (PTCD) was made. The treatment given, its outcome and histo-pathological examination (HPE) report were noted. Results then analysed in terms of how many cases needed HPE and in how many did PTCD match with HPE reports. Commonest lesions were of infective type (64.5%) followed by cysts and neoplastic which together contributed for 26.9% cases and others like congenital, traumatic, depositive etc., contributed for 8.6%. Totally, 25.8% sent for HPE; 94.4% did match with PTCD. Accuracy in clinical diagnosis is good with a thorough understanding of physical characteristics of lid mass lesions. Studies on a large scale would be extremely beneficial for the practicing ophthalmologists and the training residents and also for public health-care planning.
目的分析眼周良性病变临床诊断的准确性。对279例临床诊断和/或组织病理学证实的眼睑肿块病变进行前瞻性、干预性研究。就诊时,详细的人口统计数据、症状、发现肿块后的持续时间、肿块的位置、大小和外观、眼睑肿块的进展/消退/复发(如有)和相关的全身性疾病。然后进行治疗前临床诊断(PTCD)。观察治疗结果及组织病理检查(HPE)报告。然后分析结果,有多少病例需要HPE,有多少PTCD与HPE报告相匹配。最常见的病变是感染性病变(64.5%),其次是囊肿和肿瘤,占26.9%,其他如先天性、外伤性、阴性等占8.6%。总共有25.8%寄给了惠普;94.4%与PTCD相符。对眼睑肿块病变的物理特征有充分的了解,临床诊断的准确性较高。大规模的研究对实习眼科医生和实习住院医师以及公共卫生保健规划都非常有益。
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引用次数: 0
Progression of myopia in school-aged children after COVID-19 home confinement: A systematic review 新冠肺炎居家隔离后学龄儿童近视进展的系统评价
Pub Date : 2023-02-15 DOI: 10.18231/j.ijooo.2022.052
M. Masihuzzaman, Smita Kunwar, G. Bhardwaj
The systematic review attempts to examine all the data concerning digital screen use's influence on myopia development in a COVID-19 epidemic.: The literature was searched on PubMed and Science Direct from December 2019 to September 2022. Using the Preferred Reporting Item for Systematic Review and Meta-Analyses (PRISMA) criteria, a total of 12 research papers were chosen for thorough evaluation after the exclusion criteria. Spherical equivalent refraction and axial length were outcomes of myopia progression. Time spent using digital devices and time spent exercising outside were examined as factors. Greater stress, increased use of electronic gadgets like laptops, tablets, and cell phones, as well as less time spent outside, have all been linked to an increase in the prevalence of myopia. Additionally, we discovered that the COVID-19 pandemic's commencement significantly changed children's behaviors since there was a switch from in-person instruction to online learning and a decline in outdoor activities because of home quarantine. : In children who participated in remote learning during the COVID-19 lockdown, increased reliance on digital devices for online classes has either caused or worsened visual disturbances like the rapid progression of myopia, symptoms of dry eye and visual fatigue, and vergence and accommodation disturbances. The outcomes of this methodical study show that myopia development is significantly impacted using digital screens during the COVID-19 pandemic.
本系统综述试图检查COVID-19疫情中数字屏幕使用对近视发展影响的所有数据。检索时间为2019年12月至2022年9月,检索时间为PubMed和Science Direct。采用系统评价和荟萃分析首选报告项目(PRISMA)标准,在排除标准后,共选择12篇研究论文进行全面评估。球等效屈光度和眼轴长度是近视进展的结果。使用电子设备的时间和户外锻炼的时间被视为影响因素。更大的压力、笔记本电脑、平板电脑和手机等电子产品的使用增加,以及户外活动时间的减少,都与近视患病率的增加有关。此外,我们发现,新冠肺炎大流行的开始显著改变了儿童的行为,因为他们从面对面的教学转向了在线学习,而且由于家庭隔离,户外活动减少了。在COVID-19封锁期间参加远程学习的儿童中,越来越多地依赖数字设备进行在线课程,导致或加剧了视觉障碍,如近视的快速进展、干眼和视觉疲劳症状、趋同和适应障碍。这项系统研究的结果表明,在COVID-19大流行期间,使用数字屏幕对近视的发展有显著影响。
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引用次数: 0
Traumatic pseudophacocele: A case report with review of literature 外伤性假囊肿1例并文献复习
Pub Date : 2023-02-15 DOI: 10.18231/j.ijooo.2022.060
M. Israel, Sunil Biradar, M. Kuruvila, N. Sankolli
A elderly male presented with painful loss of vision in the left eye for 20 days with expulsion of intra-ocular content following a blunt trauma. The best corrected visual acuity was counting fingers close to face (CF-CF). Slit lamp examination revealed ciliary tissue prolapse with gaping of incision scar along with a posterior synechia, iris pigments, vitreous in Anterior chamber, cells and flare. Patients presented aphakic and had the extruded rigid PMMA IOL with a broken haptic with him. Fundoscopic examination and B scan imaging were suggestive of vitreous haemorrhage. Pseudophacocele happens following blunt trauma leading to dehiscence of the corneo-scleral wound scar. Subconjunctival dislocation is the most common type, however sub-choroidal dislocation has also been seen. Our case is an extreme one where the IOL is completely extruded from the eye.An early diagnosis can help prevent serious infective complications and have good visual outcomes.
一位老年男性在钝性外伤后左眼疼痛性视力丧失20天并伴有眼内内容物排出。最佳矫正视力是数近脸手指(CF-CF)。裂隙灯检查显示睫状体组织脱垂,切口瘢痕裂开,伴有后粘连,虹膜色素,前房玻璃体,细胞和光斑。患者表现为失语症,并与他有挤压刚性PMMA IOL与触觉断裂。眼底镜检查及B超提示玻璃体出血。假性结膜炎发生在钝性创伤后,导致角膜巩膜伤口瘢痕开裂。结膜下脱位是最常见的脱位类型,但也见过脉络膜下脱位。我们的病例是一个极端的例子,人工晶体完全从眼睛中挤出。早期诊断可以帮助预防严重的感染并发症,并有良好的视力效果。
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引用次数: 0
A case of dermoid cyst 皮样囊肿1例
Pub Date : 2023-02-15 DOI: 10.18231/j.ijooo.2022.059
K. Damodaran, Vijay Chopra
Dermoid cyst is a common ocular tumour, it accounts for 3-9% of paediatic ocular tumour. Childers with dermoid tumour persent with other congenital abnormality 13 year old girl presented to our OPD, with complains of swelling in her left eye upperlid since birth, patient has multiple facial anomalies. On ocular examination, her vision in both eyes were 6/6. A 3*3cm noted in the left upper lid near the lateral canthus. Clinical diagnosis of Dermoid cyst left eye upperlid made. A surgical excision biopsy was planned under General anaesthesia. Intraoperatively the cyst removed with the cyst wall intact. Cut section revealed cystic lesion with tangle of hair follicles. Specimen sent for histopathology. HPE confirmed the diagnosis of teratomatous dermoid cyst. Dermoid cysts account for 5% of all orbital lesions and are among the most common orbital tumors of childhood. Ophthalmologist should be aware to surgically excise these cyst meticulously so as to provide good cosmetic result to the patient.
皮样囊肿是一种常见的眼部肿瘤,占小儿眼部肿瘤的3-9%。儿童皮样瘤合并其他先天性异常13岁女孩到我们的门诊就诊,主诉自出生以来左眼上眼睑肿胀,患者有多处面部异常。眼科检查,双眼视力为6/6。左上眼睑靠近外眼角处有3*3cm的肿块。左眼上眼睑皮样囊肿的临床诊断。在全身麻醉下计划手术切除活检。术中囊肿切除,囊肿壁完好。切面显示囊性病变伴毛囊缠结。标本送组织病理学检查。HPE确诊为畸胎性皮样囊肿。皮样囊肿占所有眼眶病变的5%,是儿童最常见的眼眶肿瘤之一。眼科医生应注意对这些囊肿进行细致的手术切除,以便为患者提供良好的美容效果。
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引用次数: 0
The outcome of microbiologically proven fungal keratitis following standard treatment protocol 微生物学证实的真菌性角膜炎遵循标准治疗方案的结果
Pub Date : 2023-02-15 DOI: 10.18231/j.ijooo.2022.055
Muliha Rahman, Ashim Kumar Paul, S. Kadir, Mohamed Abdus Salam, Md. Abdul Muyeed, Chandana Sultana, M. Mujtaba, Asm Moin Uddin, T. Rahman
To describe the baseline characteristics, microbiological spectrum, therapy and assess the visual outcome in patients proven with fungal keratitis following standard treatment protocol. This longitudinal study was reviewed all patients with culture-proven fungal keratitis over a year at a tertiary referral facility in Bangladesh. All of the patients who had corneal stromal infiltrates had their corneal scrapings subjected to the normal microbiologic examination process, as well as a smear and culture-guided antimicrobial medication. Epidemiological features of patients (n=100), the mean age of patients was 55.6±9.8 years. More in the age group 51 to 60 years (28%). Males were more predominant (67%), commonly come from rural areas (59%). More were agriculture in workers (57%). Predisposing factors in fungal keratitis were trauma with vegetative matter (58%), herpetic keratitis (16%), penetrating keratoplasty (10%), extended wear of contact lens(12%), LASIK(4%). Treatment taken by another ophthalmologist before the presentation (46%). Low vision (20/50 to 20/160) was found in 58% cases and legal blindness (20/200 to worse ) was 40% of cases on visual acuity test at presentation. Filamentous Aspergillus (68%), Fusarium (2%), Scedosporium species (6%) and Candida(20%) were found by doing culture. Surgical intervention was needed in 36% of cases with topical and systemic anti fungal medications for management. Visual acuity after treatment was 20/40 or better in 16% of cases, low vision (20/50 to 20/160) in 39% of cases and legal blindness (20/200 to worse) in 45% of cases. Fungal keratitis causes irreparable vision damage. Yeast infections were less common than infections with filamentous fungus, which were typically treated more aggressively through both medicinal and surgical means. Similar durations of infections and visual results were observed in filamentous and yeast keratitis. In 80% of the cases where it was done, antifungal susceptibility testing had an impact on the course of treatment.
描述标准治疗方案下真菌性角膜炎患者的基线特征、微生物谱、治疗并评估视力结果。这项纵向研究回顾了孟加拉国一家三级转诊机构一年多来所有经培养证实的真菌性角膜炎患者。所有角膜间质浸润患者均对角膜刮屑进行正常的微生物学检查,并在涂片和培养指导下进行抗菌药物治疗。患者流行病学特征(n=100),患者平均年龄为55.6±9.8岁。51岁至60岁年龄组的比例更高(28%)。男性占多数(67%),通常来自农村地区(59%)。更多的是农业工人(57%)。真菌性角膜炎的易感因素为植物性外伤(58%)、疱疹性角膜炎(16%)、穿透性角膜移植术(10%)、隐形眼镜佩戴时间过长(12%)、LASIK(4%)。就诊前接受过其他眼科医生的治疗(46%)。视力低下(20/50 ~ 20/160)占58%,法定失明(20/200及以下)占40%。培养检出丝状曲霉(68%)、镰刀菌(2%)、隐孢子菌(6%)和念珠菌(20%)。36%的病例需要手术干预,局部和全身抗真菌药物治疗。治疗后视力达到20/40或更好的占16%,低视力(20/50至20/160)占39%,法定失明(20/200及以下)占45%。真菌性角膜炎会造成无法修复的视力损害。酵母菌感染比丝状真菌感染更少见,丝状真菌感染通常通过药物和手术手段进行更积极的治疗。丝状角膜炎和酵母菌性角膜炎的感染持续时间和视觉结果相似。在80%的病例中,抗真菌药敏试验对治疗过程有影响。
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引用次数: 0
Comparison of accommodative facility and vergence facility with and without myopia 近视眼与非近视眼调节设施与会聚设施的比较
Pub Date : 2023-02-15 DOI: 10.18231/j.ijooo.2022.056
Syeda Sadiya Ikram, N. R., S. Puri
To compare accommodation facility and vergence facility in eyes with myopia and emmetropia.It was a hospital-based comparative study conducted in the Outpatient Department of Ophthalmology. Accommodative and vergence facility measurements were taken with accommodative and vergence flippers.This study was done on 50 subjects, age group between 18-30 Years and it was approved by the IRB committee. This study has done to compare the values of accommodative facility and vergence facility between myopic emmetropic patients. The accommodative facility was measured using accommodative flippers. It was done both monocularly and binocularly for each subject at 3m and 40cm. Vergence facility was measured using vergence flippers. It was confirmed that Accommodative facility [Distance and Near] in right eye, left eye, and botheye was observed as significantly lesser in Myopic patients than Emmetropia. Also, the Vergence facility wasobserved as significantly lesser in Myopic patients than the Emmetropic patients.A reduced accommodative facility and vergence facility was found in myopes in comparison to emmetropia. At both distance and near, the mean facility was less for myopic eyes in comparison with emmetropic eyes.
比较近视眼和远视眼的调节功能和会聚功能。这是一项在眼科门诊部进行的以医院为基础的比较研究。用调节和收敛鳍进行调节和收敛设施测量。这项研究有50名受试者,年龄在18-30岁之间,并得到了IRB委员会的批准。本研究比较了屈光不正近视患者的调节功能和会聚功能的价值。采用调节鳍测量调节能力。每个受试者分别在3米和40厘米处进行单眼和双目观察。用收敛鳍测量收敛能力。证实近视患者右眼、左眼和双眼的调节功能(距离和近距离)明显低于远视。此外,我们还观察到近视患者的会聚功能明显低于远视患者。与远视相比,近视眼的调节功能和聚光功能减少。近视眼与远视眼相比,近视眼的平均视力较弱。
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引用次数: 0
Orbital apex syndrome: A review 眶尖综合征:综述
Pub Date : 2023-02-15 DOI: 10.18231/j.ijooo.2022.051
R. P. Maurya, Kajal Pal, S. Kadir, Murtuza Nuruddin, Aalok Kumar, V. Singh, Kokil Tiwari, Vibha Singh
An orbital apex syndrome (OAS) has been described previously as a syndrome involving damage to the ocular motor and sensory nerves in association with optic nerve dysfunction. Patients usually present with signs and symptoms derived from the involvement of structures within the orbital apex, the superior orbital fissure, and the cavernous sinus. Visual loss from optic neuropathy and ophthalmoplegia involving multiple cranial nerves are the hallmarks of orbital apex syndrome. Historically, superior orbital fissure, orbital apex, and cavernous sinus are being used to define the anatomical locations of a disease process. However, the diagnostic evaluation and management are similar for each of these entities. The authors reviewed the literature on evaluating disorders involving the orbital apex and it’s diagnosis.
眶尖综合征(OAS)以前被描述为一种涉及与视神经功能障碍相关的眼运动和感觉神经损伤的综合征。患者通常表现出由眶尖、眶上裂和海绵窦内结构受累引起的体征和症状。视神经病变引起的视力丧失和累及多颅神经的眼麻痹是眶尖综合征的特征。历史上,眶上裂、眶尖和海绵窦被用来确定疾病过程的解剖位置。然而,这些实体的诊断评估和管理是相似的。作者回顾了有关眶尖病变的评价及诊断的文献。
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引用次数: 0
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IP International Journal of Ocular Oncology and Oculoplasty
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