Shailesh Pande, A. Pais, Gauri N. Pradhan, Yamini Jadhav, Chaitali Parab, Bharat Kalthe, S. Matkar
Loss of pregnancy either naturally or by medical termination is a destructive experience to the couple, especially those experiencing recurrent pregnancy losses (RPL). It is important to rule out the genetic aspect as the cause of pregnancy wastages. This retrospective study aimed to determine the frequency of chromosomal abnormalities and its various cytogenetic types in the samples received by Metropolis Healthcare laboratory, Mumbai. This study was conducted on the samples referred for chromosomal karyotyping with a history of Bad Obstetric History (BOH). The couples who had an experience of two or more pregnancy losses were included in this study. Out of the 2102 samples referred, chromosomal abnormality was recorded in 384 (18.27%) cases. Out of chromosomal abnormal cases, 126 (5.99%) patients had reciprocal translocations out of which 27 (21.43%) were Robertsonian translocations. Inversion of chromosome 9 was seen in 81 (21.09%) patients, while inversion Y in 28 (7.29%) patients, and polymorphic variation like increase in length of satellite or heterochromatic region recorded in almost 149 (38.30%) patients. Cytogenetic evaluation of couples with recurrent pregnancy losses (RPL) is very important as after knowing the parental chromosomal pattern appropriate counseling can be offered to know the risk of recurrence, option of prenatal diagnosis and also opens the option of reproduction in some cases. This will also help them to have a cytogenetically healthy baby. Since the cytogenetic abnormalities are usually familial, the close blood relatives may also be benefited once the abnormality is detected.
{"title":"Cytogenetics and Importance of Genetic Counselling in Recurrent Pregnancy Losses: Experience from Tertiary Care Laboratory","authors":"Shailesh Pande, A. Pais, Gauri N. Pradhan, Yamini Jadhav, Chaitali Parab, Bharat Kalthe, S. Matkar","doi":"10.21013/jas.v9.n1.p2","DOIUrl":"https://doi.org/10.21013/jas.v9.n1.p2","url":null,"abstract":"Loss of pregnancy either naturally or by medical termination is a destructive experience to the couple, especially those experiencing recurrent pregnancy losses (RPL). It is important to rule out the genetic aspect as the cause of pregnancy wastages. This retrospective study aimed to determine the frequency of chromosomal abnormalities and its various cytogenetic types in the samples received by Metropolis Healthcare laboratory, Mumbai. This study was conducted on the samples referred for chromosomal karyotyping with a history of Bad Obstetric History (BOH). The couples who had an experience of two or more pregnancy losses were included in this study. Out of the 2102 samples referred, chromosomal abnormality was recorded in 384 (18.27%) cases. Out of chromosomal abnormal cases, 126 (5.99%) patients had reciprocal translocations out of which 27 (21.43%) were Robertsonian translocations. Inversion of chromosome 9 was seen in 81 (21.09%) patients, while inversion Y in 28 (7.29%) patients, and polymorphic variation like increase in length of satellite or heterochromatic region recorded in almost 149 (38.30%) patients. Cytogenetic evaluation of couples with recurrent pregnancy losses (RPL) is very important as after knowing the parental chromosomal pattern appropriate counseling can be offered to know the risk of recurrence, option of prenatal diagnosis and also opens the option of reproduction in some cases. This will also help them to have a cytogenetically healthy baby. Since the cytogenetic abnormalities are usually familial, the close blood relatives may also be benefited once the abnormality is detected.","PeriodicalId":14487,"journal":{"name":"IRA-International Journal of Applied Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79702230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
One of the important subsidiary materials of livestock units is excreta. The livestock waste (including the combination of the Cattle Manure and products case in the bed) as a valuable source of the minerals (Nitrogen 1.78 % , phosphor us 0.5% and potassium 0.99%).For the transportation of the cattle manure in the natural state is difficult and costly due to being low the special mass and the nature of mass. It is produced around 6 million thons the cattle manure yearly in Iran which it is usually filled in the place according to the lack of organic materials of the soils country, the use of the cattle manure causes increasing the productivity of crops. We usually need to some of the mechanical and thermal properties of the cattle manure for producing the pellet by Extruder, so we Survey some of the mechanical and thermal properties of the cattle manure pellet in this research such as the shear stress and the coefficient of thermal diffusivity cattle manure. We obtain the coefficient of the thermal diffusivity manure (
{"title":"Determination of Some Mechanical and Thermal Properties of Cattle Manure Pellets","authors":"Javad Rezaeifar, M. Pourjafar","doi":"10.21013/JAS.V9.N1.P1","DOIUrl":"https://doi.org/10.21013/JAS.V9.N1.P1","url":null,"abstract":"One of the important subsidiary materials of livestock units is excreta. The livestock waste (including the combination of the Cattle Manure and products case in the bed) as a valuable source of the minerals (Nitrogen 1.78 % , phosphor us 0.5% and potassium 0.99%).For the transportation of the cattle manure in the natural state is difficult and costly due to being low the special mass and the nature of mass. It is produced around 6 million thons the cattle manure yearly in Iran which it is usually filled in the place according to the lack of organic materials of the soils country, the use of the cattle manure causes increasing the productivity of crops. We usually need to some of the mechanical and thermal properties of the cattle manure for producing the pellet by Extruder, so we Survey some of the mechanical and thermal properties of the cattle manure pellet in this research such as the shear stress and the coefficient of thermal diffusivity cattle manure. We obtain the coefficient of the thermal diffusivity manure (","PeriodicalId":14487,"journal":{"name":"IRA-International Journal of Applied Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73007729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fuzzy logic is a development of Boolean logic dealing with the meaning of sectional truth. Whiles classical logic holds that everything can be expressed in double terms (0 or 1, black or white, yes or no). Fuzzy logic permits the use of linguistic values of variables and ambiguous relationships for modeling system treatment and it is a strong concept for handling time-varying, non-linear and adaptive systems. Because of need to improving agricultural systems and enhancing the farmer's income, the current study presents a review of fuzzy logic literature, applications to agricultural systems and fuzzy modeling techniques. One example has been expressed the steps of building a fuzzy model and consider the strategies for improving of agricultural systems.
{"title":"Application of Fuzzy Logic in Agricultural Systems: A Review","authors":"M. Pourjafar, M. Mazloomzadeh","doi":"10.21013/jas.v8.n3.p1","DOIUrl":"https://doi.org/10.21013/jas.v8.n3.p1","url":null,"abstract":"Fuzzy logic is a development of Boolean logic dealing with the meaning of sectional truth. Whiles classical logic holds that everything can be expressed in double terms (0 or 1, black or white, yes or no). Fuzzy logic permits the use of linguistic values of variables and ambiguous relationships for modeling system treatment and it is a strong concept for handling time-varying, non-linear and adaptive systems. Because of need to improving agricultural systems and enhancing the farmer's income, the current study presents a review of fuzzy logic literature, applications to agricultural systems and fuzzy modeling techniques. One example has been expressed the steps of building a fuzzy model and consider the strategies for improving of agricultural systems.","PeriodicalId":14487,"journal":{"name":"IRA-International Journal of Applied Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81918960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-10DOI: 10.21013/JAS.V08.N03.P01
Ngounou Batchanji Steve, Feumba Dibanda Romelle, Yadang Germaine, Nyobe Emillienne Carine, Achegui Nestor, Ndanga Thomas, Medoua Nama Gabriel
Palm wine is the commonest name of the beverage obtained from fermented palm sap, the exudate from tapped unopened spathe of oil palm tree (Elaeis guineensis). This refreshing wine of West and Central Africa is very sweet but within 24 hours the concentration of sucrose falls to less than 50% the initial amounts due to a rapid sugar fermentation by microorganisms. In Cameroon, Central Africa, traditional attempts to preserve palm wine imply the introduction of natural preservatives mostly barks and leaves from edible or medicinal plants. The leaves of Cymbopogon citratus, Pimenta racemosa, Vernonia amygdalina, Ocimum basilicum and the barks and the leaves of Garcinia lucida and of Adansonia digitata commonly used in palm wine preservation were analyzed for their chemical composition. The results showed that lipid, protein, ash, crude fiber, total sugars and vitamin C contents were respectively from 15.70 ± 1.13 to 23.57 ± 1.80%, from 8.38 ± 0.38 to 43.81 ± 3.69%, from 1.14 ± 0.17 to 10.06 ± 0.39%, from 11.74 ± 1.11 to 48.42 ± 0.55%, and from 1.49 ± 0.02 to 22.56 ± 0.59% and from 55.76 ± 3.15 to 175.71 ± 2.09 μg /100 g dw. The phyto-chemicals levels were respectively from 1.37 ± 0.22 to 3.61 ± 0.6 % for total alkaloids, 2.66 ± 0.12 to 4.80 ± 0.24 % for total phenolics and 0.57 ± 0.09 to 1.88 ± 0.09 mg /100 g dw for total saponins. Concerning anti-nutrients, the oxalates levels were higher than the threshold value (250 mg/100 g) reported as safety limit. Despise the proven antimicrobial benefits of alkaloids, saponins and phenolics found in those leaves and barks, caution shall be paid during their use due to their high oxalates levels.
{"title":"Chemical Composition of Some Natural Palm Wine Preservatives","authors":"Ngounou Batchanji Steve, Feumba Dibanda Romelle, Yadang Germaine, Nyobe Emillienne Carine, Achegui Nestor, Ndanga Thomas, Medoua Nama Gabriel","doi":"10.21013/JAS.V08.N03.P01","DOIUrl":"https://doi.org/10.21013/JAS.V08.N03.P01","url":null,"abstract":"Palm wine is the commonest name of the beverage obtained from fermented palm sap, the exudate from tapped unopened spathe of oil palm tree (Elaeis guineensis). This refreshing wine of West and Central Africa is very sweet but within 24 hours the concentration of sucrose falls to less than 50% the initial amounts due to a rapid sugar fermentation by microorganisms. In Cameroon, Central Africa, traditional attempts to preserve palm wine imply the introduction of natural preservatives mostly barks and leaves from edible or medicinal plants. The leaves of Cymbopogon citratus, Pimenta racemosa, Vernonia amygdalina, Ocimum basilicum and the barks and the leaves of Garcinia lucida and of Adansonia digitata commonly used in palm wine preservation were analyzed for their chemical composition. The results showed that lipid, protein, ash, crude fiber, total sugars and vitamin C contents were respectively from 15.70 ± 1.13 to 23.57 ± 1.80%, from 8.38 ± 0.38 to 43.81 ± 3.69%, from 1.14 ± 0.17 to 10.06 ± 0.39%, from 11.74 ± 1.11 to 48.42 ± 0.55%, and from 1.49 ± 0.02 to 22.56 ± 0.59% and from 55.76 ± 3.15 to 175.71 ± 2.09 μg /100 g dw. The phyto-chemicals levels were respectively from 1.37 ± 0.22 to 3.61 ± 0.6 % for total alkaloids, 2.66 ± 0.12 to 4.80 ± 0.24 % for total phenolics and 0.57 ± 0.09 to 1.88 ± 0.09 mg /100 g dw for total saponins. Concerning anti-nutrients, the oxalates levels were higher than the threshold value (250 mg/100 g) reported as safety limit. Despise the proven antimicrobial benefits of alkaloids, saponins and phenolics found in those leaves and barks, caution shall be paid during their use due to their high oxalates levels.","PeriodicalId":14487,"journal":{"name":"IRA-International Journal of Applied Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84733942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Some physical properties of Iranian Jujube fruit were evaluated. Jujube fruit samples mean values of length, width, thickness were found as 18.005mm, 14.96 mm, 15.26 mm. Arithmetic mean diameter, geometric mean diameter were found as 16.08mm, 16.01 respectively and surface area, Sphericity, porosity, mass, volume, bulk density and true density were also found as: 805.65 mm 2 ,89%, 77.2%, 1.45gr, 2.61 cm 3 , 0.23gr cm -3 , 0.55gr cm -3 respectively. Projected area perpendicular to length, width and thickness were measured as, 152.03 mm 2 , 220.02 mm 2 , 271.4mm 2 respectively. With comparison between friction coefficients on different surface for Jujube fruit. The results showed that the static coefficient of friction was more than dynamic coefficient of friction.The tests done on the galvanized steel surface, plywood and glass surface. The most coefficient of friction was found on the plywood surface and the least coefficient of friction was measured on the glass surface.
对伊朗枣果实的一些物理特性进行了评价。红枣果实样品的长、宽、厚均值分别为18.00mm、14.96 mm、15.26 mm。算术平均直径、几何平均直径分别为16.08mm、16.01，比表面积、球度、孔隙度、质量、体积、容重、真密度分别为805.65 mm 2、89%、77.2%、1.45gr、2.61 cm 3、0.23gr cm -3、0.55gr cm -3。垂直于长度、宽度和厚度的投影面积分别为152.03 mm 2、220.02 mm 2、271.4mm 2。对红枣果实不同表面摩擦系数进行了比较。结果表明:静摩擦系数大于动摩擦系数;试验在镀锌钢板表面、胶合板表面和玻璃表面进行。胶合板表面的摩擦系数最大，玻璃表面的摩擦系数最小。
{"title":"Determination of Some Physical Properties of Dried Jujube Fruit","authors":"M. Pourjafar","doi":"10.21013/JAS.V8.N2.P1","DOIUrl":"https://doi.org/10.21013/JAS.V8.N2.P1","url":null,"abstract":"Some physical properties of Iranian Jujube fruit were evaluated. Jujube fruit samples mean values of length, width, thickness were found as 18.005mm, 14.96 mm, 15.26 mm. Arithmetic mean diameter, geometric mean diameter were found as 16.08mm, 16.01 respectively and surface area, Sphericity, porosity, mass, volume, bulk density and true density were also found as: 805.65 mm 2 ,89%, 77.2%, 1.45gr, 2.61 cm 3 , 0.23gr cm -3 , 0.55gr cm -3 respectively. Projected area perpendicular to length, width and thickness were measured as, 152.03 mm 2 , 220.02 mm 2 , 271.4mm 2 respectively. With comparison between friction coefficients on different surface for Jujube fruit. The results showed that the static coefficient of friction was more than dynamic coefficient of friction.The tests done on the galvanized steel surface, plywood and glass surface. The most coefficient of friction was found on the plywood surface and the least coefficient of friction was measured on the glass surface.","PeriodicalId":14487,"journal":{"name":"IRA-International Journal of Applied Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85201331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jean Stéphane N’dri, M. Koné, C. Kodjo, S. T. Affi, Ahmont Landry Claude Kablan, O. Ouattara, Doh Soroand, N. Ziao
This QSAR study, which involved a series of Azetidinones derived from 4,4'-diaminodiphenylsulfone (dapsone), yielded two models based on molecular descriptors and the antibacterial activities Escherichia coli and Staphylococcus aureus.The molecular descriptors were obtained by applying the methods of quantum chemistry at the B3LYP/6-31G (d) level. The statistical indicators of the first model which is a function of the Escherichia coli activity are: the coefficient of determination R 2 equals 0.992, the standard deviation S equals 0.342, the Fischer coefficient F equals 185.088 and the cross-validation coefficient Q 2 CV equals 0.992. Those of the second model showing the activity of Staphylococcus aureus are: the regression coefficient R 2 = 0.987, a standard deviation S=0.193, the Fischer coefficient F=114.955 and the cross-validation coefficient Q 2 CV = 0.987. These models have good statistical performances. The quantum descriptors of dipole moment (μ), global softness (σ) and electronegativity (χ) are responsible of the antibacterial activity of the Azetidinones derived from dapsone. In addition, the dipole moment is the priority descriptor for the prediction of the antibacterial activity of the studied compounds. The Eriksson et al. acceptance criteria used for the test set is verified. The values of the dtheo/dexp ratio of the theoretical and experimental activities for the test set tend towards unity.
{"title":"Quantitative Activity Structure Relationship (QSAR) of a Series of Azetidinones Derived from Dapsone by the Method of Density Functional Theory (DFT)","authors":"Jean Stéphane N’dri, M. Koné, C. Kodjo, S. T. Affi, Ahmont Landry Claude Kablan, O. Ouattara, Doh Soroand, N. Ziao","doi":"10.21013/JAS.V8.N2.P2","DOIUrl":"https://doi.org/10.21013/JAS.V8.N2.P2","url":null,"abstract":"This QSAR study, which involved a series of Azetidinones derived from 4,4'-diaminodiphenylsulfone (dapsone), yielded two models based on molecular descriptors and the antibacterial activities Escherichia coli and Staphylococcus aureus.The molecular descriptors were obtained by applying the methods of quantum chemistry at the B3LYP/6-31G (d) level. The statistical indicators of the first model which is a function of the Escherichia coli activity are: the coefficient of determination R 2 equals 0.992, the standard deviation S equals 0.342, the Fischer coefficient F equals 185.088 and the cross-validation coefficient Q 2 CV equals 0.992. Those of the second model showing the activity of Staphylococcus aureus are: the regression coefficient R 2 = 0.987, a standard deviation S=0.193, the Fischer coefficient F=114.955 and the cross-validation coefficient Q 2 CV = 0.987. These models have good statistical performances. The quantum descriptors of dipole moment (μ), global softness (σ) and electronegativity (χ) are responsible of the antibacterial activity of the Azetidinones derived from dapsone. In addition, the dipole moment is the priority descriptor for the prediction of the antibacterial activity of the studied compounds. The Eriksson et al. acceptance criteria used for the test set is verified. The values of the dtheo/dexp ratio of the theoretical and experimental activities for the test set tend towards unity.","PeriodicalId":14487,"journal":{"name":"IRA-International Journal of Applied Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90100587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. David, Raghu Ranjan, R. DineshM, M. Dharmar, C. AmaranthB, Sharmila Arjunan
The purpose of this study was to quantitatively evaluate buccal cortical bone thickness in the maxilla and mandible so as to provide guidelines for mini-implant placement. Cone beam computed tomographic scans of thirty patients (Age 16-30 years) were collected from preorthodontic records. Each measurement area was coded with a number beginning in the maxillary right quadrant distal to the second molar with number 1 and ending in the mandibular right quadrant distal to the second molar with number 30. For analysis these measurement areas were also grouped as sextants. Three measurement points were then defined at 2 mm, 4 mm and 6 mm from the alveolar crest in each measurement. The measuring locations were recorded on the four quadrants, resulting in 90 locations in the buccal cortical plate of maxillary and mandibular arch. The region of interest was explored at each measuring location of the 30 sites using Galileos software. The optimal site for miniimplant placement in the anterior region is between the central and lateral incisors in the maxilla and between the lateral incisor and the canine in the mandible at the 6-mm level from the alveolar crest. At the buccal aspect of the posterior region of both jaws, the optimal sites are between between the first and second molars i.e. in the Maxillary arch at 4 mm level on the right side and left side and in the Mandibular arch at 6 mm level on the right side and left side.
{"title":"Analysis of Buccal Cortical Plate Thickness for Placement of Mini-Implants – A CBCT Study","authors":"R. David, Raghu Ranjan, R. DineshM, M. Dharmar, C. AmaranthB, Sharmila Arjunan","doi":"10.21013/JAS.V8.N1.P3","DOIUrl":"https://doi.org/10.21013/JAS.V8.N1.P3","url":null,"abstract":"The purpose of this study was to quantitatively evaluate buccal cortical bone thickness in the maxilla and mandible so as to provide guidelines for mini-implant placement. Cone beam computed tomographic scans of thirty patients (Age 16-30 years) were collected from preorthodontic records. Each measurement area was coded with a number beginning in the maxillary right quadrant distal to the second molar with number 1 and ending in the mandibular right quadrant distal to the second molar with number 30. For analysis these measurement areas were also grouped as sextants. Three measurement points were then defined at 2 mm, 4 mm and 6 mm from the alveolar crest in each measurement. The measuring locations were recorded on the four quadrants, resulting in 90 locations in the buccal cortical plate of maxillary and mandibular arch. The region of interest was explored at each measuring location of the 30 sites using Galileos software. The optimal site for miniimplant placement in the anterior region is between the central and lateral incisors in the maxilla and between the lateral incisor and the canine in the mandible at the 6-mm level from the alveolar crest. At the buccal aspect of the posterior region of both jaws, the optimal sites are between between the first and second molars i.e. in the Maxillary arch at 4 mm level on the right side and left side and in the Mandibular arch at 6 mm level on the right side and left side.","PeriodicalId":14487,"journal":{"name":"IRA-International Journal of Applied Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78273988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kammegne Adelaide Maguie, N. J. Nsami, Kouotou Daouda, Che Nangah Randy, K. J. Mbadcam
The adsorption of Cu2+ions on activated carbon based canarium schweinfurthii impregnated with ZnCl2 was studied. The shells of canarium schweinfurthii were impregnated with ZnCl2 at varying ZnCl2 concentrations, temperature, residence time while keeping the heating rate fixed at 10 °C / min and the ratio of impregnation of 1:1. The activated carbon with the highest surface area in term of iodine number of 860,817 mg/g, the highest methylene blue of 741,6 mg/g and 74,66 % of yield of carbon was obtained at 650 °C, 60 % ZnCl 2 and 30min. From the batch adsorption studies, the equilibrium time was found to be 40 min. Analysis of equilibrium isotherm models revealed a good correlation of the experimental data with the Tempkin (R 2 = 0.909) model. This confirms a high affinity of the activated carbon for Cu 2+ ions on the heterogeneous surface. The value of energy obtained from the Tempkin model was 60,606 J/mol and the presence of pics between 487 cm-1 to 871 cm-1 indicating that physisorption and chemisorption were taking place during this sorption. The pseudo-second order kinetics(R 2 = 0.999) governs the adsorption of Cu2+ions on this activated carbon.
{"title":"Adsorption Study of the Removal of Copper (II) Ions using Activated Carbon Based Canarium Schweinfurthii Shells Impregnated with ZnCl2","authors":"Kammegne Adelaide Maguie, N. J. Nsami, Kouotou Daouda, Che Nangah Randy, K. J. Mbadcam","doi":"10.21013/JAS.V8.N1.P2","DOIUrl":"https://doi.org/10.21013/JAS.V8.N1.P2","url":null,"abstract":"The adsorption of Cu2+ions on activated carbon based canarium schweinfurthii impregnated with ZnCl2 was studied. The shells of canarium schweinfurthii were impregnated with ZnCl2 at varying ZnCl2 concentrations, temperature, residence time while keeping the heating rate fixed at 10 °C / min and the ratio of impregnation of 1:1. The activated carbon with the highest surface area in term of iodine number of 860,817 mg/g, the highest methylene blue of 741,6 mg/g and 74,66 % of yield of carbon was obtained at 650 °C, 60 % ZnCl 2 and 30min. From the batch adsorption studies, the equilibrium time was found to be 40 min. Analysis of equilibrium isotherm models revealed a good correlation of the experimental data with the Tempkin (R 2 = 0.909) model. This confirms a high affinity of the activated carbon for Cu 2+ ions on the heterogeneous surface. The value of energy obtained from the Tempkin model was 60,606 J/mol and the presence of pics between 487 cm-1 to 871 cm-1 indicating that physisorption and chemisorption were taking place during this sorption. The pseudo-second order kinetics(R 2 = 0.999) governs the adsorption of Cu2+ions on this activated carbon.","PeriodicalId":14487,"journal":{"name":"IRA-International Journal of Applied Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85697625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim : To construct an express a mouse-human chimeric antibody against IL-23p19 using a synthetic peptide as immunogen. Methods : Immunization of mice with a synthetic peptide derived from the IL-23p19 sequence and generation of hybridoma secreting specific antibodies. The chimeric antibody was created using two eukaryotic plasmid constructions; one of them carrying the light mouse-human chain and the other the heavy mouse-human chain. CHO-K1 cells were cotransfected with both plasmids and stable transfectants were grown in selective culture medium. Results : A chimeric version of anti-IL-23p19 was successfully constructed and expressed in eukaryotic cells. The expressed chimeric antibody showed specific recognition not only of the peptide used as immunogen but also the subunit p19 and the complete interleukin Il-23. Conclusion : A Chimeric antibody that was developed against a synthetic peptide, which is able to recognize the parent protein IL23 biologically active, could be developed into a targeted therapy in diseases with chronic inflammation.
{"title":"Generation of a Chimeric Antibody against a Synthetic Peptide Derived From IL-23p19 with Potential Therapeutic Application","authors":"Pérez-Etcheverry Diana, L. Carmen","doi":"10.21013/JAS.V8.N1.P1","DOIUrl":"https://doi.org/10.21013/JAS.V8.N1.P1","url":null,"abstract":"Aim : To construct an express a mouse-human chimeric antibody against IL-23p19 using a synthetic peptide as immunogen. Methods : Immunization of mice with a synthetic peptide derived from the IL-23p19 sequence and generation of hybridoma secreting specific antibodies. The chimeric antibody was created using two eukaryotic plasmid constructions; one of them carrying the light mouse-human chain and the other the heavy mouse-human chain. CHO-K1 cells were cotransfected with both plasmids and stable transfectants were grown in selective culture medium. Results : A chimeric version of anti-IL-23p19 was successfully constructed and expressed in eukaryotic cells. The expressed chimeric antibody showed specific recognition not only of the peptide used as immunogen but also the subunit p19 and the complete interleukin Il-23. Conclusion : A Chimeric antibody that was developed against a synthetic peptide, which is able to recognize the parent protein IL23 biologically active, could be developed into a targeted therapy in diseases with chronic inflammation.","PeriodicalId":14487,"journal":{"name":"IRA-International Journal of Applied Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80679093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Compaoré, B. Ouédraogo, H. Guengane, Etienne Malbila, D. Bathiébo
The present work is a contribution to the energy efficiency in the habitats by the valorization of the local building materials in Burkina Faso. A comparative numerical study on the thermal behavior and energy consumption of some habitats in local and modern building materials is carried out. The simulations were carried out using computer code written in FORTRAN language over a period of one year. Analysis of the results shows that habitats in local construction materials (BTC, BLT, adobe) have a better thermal response compared to modern building materials (hollow cinder block). Generally speaking, the temperature and humidity profiles obtained do not make it possible to ensure the summer comfort in these buildings throughout the year. The evaluation of air-conditioning loads to ensure thermal comfort in these habitats shows that they are higher respectively in the blocks, BLT, BTC, adobe constructions. We therefore consider that local building materials represent a good alternative for the search for energy efficiency in buildings.
{"title":"Role of Local Building Materials on the Energy Behaviour of Habitats in Ouagadougou","authors":"A. Compaoré, B. Ouédraogo, H. Guengane, Etienne Malbila, D. Bathiébo","doi":"10.21013/JAS.V8.N2.P3","DOIUrl":"https://doi.org/10.21013/JAS.V8.N2.P3","url":null,"abstract":"The present work is a contribution to the energy efficiency in the habitats by the valorization of the local building materials in Burkina Faso. A comparative numerical study on the thermal behavior and energy consumption of some habitats in local and modern building materials is carried out. The simulations were carried out using computer code written in FORTRAN language over a period of one year. Analysis of the results shows that habitats in local construction materials (BTC, BLT, adobe) have a better thermal response compared to modern building materials (hollow cinder block). Generally speaking, the temperature and humidity profiles obtained do not make it possible to ensure the summer comfort in these buildings throughout the year. The evaluation of air-conditioning loads to ensure thermal comfort in these habitats shows that they are higher respectively in the blocks, BLT, BTC, adobe constructions. We therefore consider that local building materials represent a good alternative for the search for energy efficiency in buildings.","PeriodicalId":14487,"journal":{"name":"IRA-International Journal of Applied Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80540763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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