Background: Leprosy is one of the oldest diseases known to mankind and is still associated with stigma. A high child proportion signifies active and recent transmission of the disease. Aim: To know the proportion of children in newly detected leprosy patients and their clinico histopathological categorisation. Methodology: This was a retrospective analysis of all leprosy patients less than 16 years of age registered at the Leprosy Clinic of GGH, Vijayawada from January2015-June2016. Results: Proportion of children among newly diagnosed leprosy patients was 9.2% .Majority of patients belonged to age group of 13 to 16 years(48%), with male preponderance. 24% patients gave family history of leprosy. 40% of patients belonged to PB type, 60% MB type. Slit skin smear was positive in 20%. According to clinical characteristics, majority of patients belonged to BT(52%) followed by TT(32%). According to histopathological characteristics majority of patients belonged to BT(48%) followed by TT(36%).Clinico Histopathological correlation in LL Hansen’s is 100%, in BT 76%.Type I reaction occurred in 2 patients(8%).Deformities were observed in 8% patients. Conclusion: Despite statistical elimination of leprosy, childhood leprosy still remains a public health problem. Early detection, treatment and contact tracing are important for reducing the burden of leprosy in the community.
{"title":"A Clinico Histopathological Study of Childhood Leprosy","authors":"D. Rao, Dr.G. Leelavathi, Dr. G. Purnima","doi":"10.9790/0853-1607018390","DOIUrl":"https://doi.org/10.9790/0853-1607018390","url":null,"abstract":"Background: Leprosy is one of the oldest diseases known to mankind and is still associated with stigma. A high child proportion signifies active and recent transmission of the disease. Aim: To know the proportion of children in newly detected leprosy patients and their clinico histopathological categorisation. Methodology: This was a retrospective analysis of all leprosy patients less than 16 years of age registered at the Leprosy Clinic of GGH, Vijayawada from January2015-June2016. Results: Proportion of children among newly diagnosed leprosy patients was 9.2% .Majority of patients belonged to age group of 13 to 16 years(48%), with male preponderance. 24% patients gave family history of leprosy. 40% of patients belonged to PB type, 60% MB type. Slit skin smear was positive in 20%. According to clinical characteristics, majority of patients belonged to BT(52%) followed by TT(32%). According to histopathological characteristics majority of patients belonged to BT(48%) followed by TT(36%).Clinico Histopathological correlation in LL Hansen’s is 100%, in BT 76%.Type I reaction occurred in 2 patients(8%).Deformities were observed in 8% patients. Conclusion: Despite statistical elimination of leprosy, childhood leprosy still remains a public health problem. Early detection, treatment and contact tracing are important for reducing the burden of leprosy in the community.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79063761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Samanta, DrJadav Chandra Sardar, P. Sengupta, A. Chatterjee, S. Lahiri
Background:JE is an emerging public health problem in India.JE vaccine has been incorporated in the National Immunization Schedule in India following mass vaccination. Objectives:To explore the experiences gathered during mass vaccination period in a tertiary care center. Methodology:A mixed method approach consisting of a cross-sectional survey and qualitative study was adopted. The qualitative study was included to obtain more in-depth understanding of the experiences and perspectives of frontline workers and the team leader in form of in depth interview of LMO of satellite center and FGDamong all PHNS involved in the activity. Result:Among 2437 vaccinees surveyed, majority belonged to 1-5 years age group followed by 6-10 years.Only half of the caregivers of surveyed population knew the purpose of vaccination and 6%perceived that the vaccine prevents ‘Dengue’. No AEFI was reported during and one months following the mass vaccination.Qualitative approach revealed huge enthusiasm among the people about the vaccine, lack of staff and space to cater large age group section and inappropriate rush during the vaccination sessions and impairment of routine vaccination during the mass vaccination period. Conclusion:Thoroughly planned systematic IEC activities and prior deployment and orientation of staffs are pre requisites for conducting suchlarge scale mass vaccination programme.
{"title":"Initiation of JE Vaccination-An Experience: A Mixed Method Study In A Tertiary Care Center of West Bengal, India","authors":"A. Samanta, DrJadav Chandra Sardar, P. Sengupta, A. Chatterjee, S. Lahiri","doi":"10.9790/0853-1607012026","DOIUrl":"https://doi.org/10.9790/0853-1607012026","url":null,"abstract":"Background:JE is an emerging public health problem in India.JE vaccine has been incorporated in the National Immunization Schedule in India following mass vaccination. Objectives:To explore the experiences gathered during mass vaccination period in a tertiary care center. Methodology:A mixed method approach consisting of a cross-sectional survey and qualitative study was adopted. The qualitative study was included to obtain more in-depth understanding of the experiences and perspectives of frontline workers and the team leader in form of in depth interview of LMO of satellite center and FGDamong all PHNS involved in the activity. Result:Among 2437 vaccinees surveyed, majority belonged to 1-5 years age group followed by 6-10 years.Only half of the caregivers of surveyed population knew the purpose of vaccination and 6%perceived that the vaccine prevents ‘Dengue’. No AEFI was reported during and one months following the mass vaccination.Qualitative approach revealed huge enthusiasm among the people about the vaccine, lack of staff and space to cater large age group section and inappropriate rush during the vaccination sessions and impairment of routine vaccination during the mass vaccination period. Conclusion:Thoroughly planned systematic IEC activities and prior deployment and orientation of staffs are pre requisites for conducting suchlarge scale mass vaccination programme.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83620294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Bone Marrow examination is an important diagnostic tool to evaluate various hematological and non-hematological diseases including both neoplastic and non-neoplastic conditions. The two separate but inter-related techniques are used such as Bone marrow aspiration(BMA) and Bone marrow biopsy(BMB) along with in the recent days introduction of Flow cytometry analysis and cytogenetic study have taken an important diagnostic tool to reach a definitive diagnosis and all these diagnostic processes are complimentary to each other. Aim and objective: This study is aimed to assess and correlate the diagnostic value of simultaneous BMA and BMB along with Flow cytometric interpretations in different hematological malignancies and non-neoplastic hematological and nonhematological diseases to establish a final diagnosis. Materials And Methods: This study involved bone marrow analysis in 164 patients out of which in 158 cases both BMA and BMB was performed simultaneously along with flow cytometry and cytogenetic study was done on some hematological malignancies and a correlation was done between all these procedures. Criteria of inclusion included the main indications for performing this procedure, the availability of full clinical data and patient consent. Result: In the present study, out of 158 cases with simultaneous BMA and BMB procedures were performed simultaneously showed 85.4% positive correlation between these two procedures. However, it was found that in cases of myelofibrosis, non-hodgkin’s lymphoma, myeloproliferative disorders and granulomas, involvement of marrow was detected better in bone marrow biopsies. And also simultaneous flowcytometry and cytogenetic analysis gives strong confirmatory diagnosis in hematological malignancies to know the origin, genetic alteration and minimal residual disease in follow –up cases for targeted therapy. Conclusion: This study concludes that in routine hematological practice BMA, BMB, Flow cytometry and Cytogenetic, all are complimentary to each other which should be done simultaneously for the better diagnostic and prognostic point of view.
{"title":"A Comparative Evaluation of Simultaneous Bone Marrow Aspiration And Bone Marrow Biopsy Interpretations In Routine Hematology Practice with Special Reference to Flow Cytometry And Cytogenetic Analysis","authors":"Raka Hota, T. Bhuyan, Sukumar Chakrabarty, Ramesh Chandra Mohanty, Raghumani Mohanty","doi":"10.9790/0853-1607015360","DOIUrl":"https://doi.org/10.9790/0853-1607015360","url":null,"abstract":"Introduction: Bone Marrow examination is an important diagnostic tool to evaluate various hematological and non-hematological diseases including both neoplastic and non-neoplastic conditions. The two separate but inter-related techniques are used such as Bone marrow aspiration(BMA) and Bone marrow biopsy(BMB) along with in the recent days introduction of Flow cytometry analysis and cytogenetic study have taken an important diagnostic tool to reach a definitive diagnosis and all these diagnostic processes are complimentary to each other. Aim and objective: This study is aimed to assess and correlate the diagnostic value of simultaneous BMA and BMB along with Flow cytometric interpretations in different hematological malignancies and non-neoplastic hematological and nonhematological diseases to establish a final diagnosis. Materials And Methods: This study involved bone marrow analysis in 164 patients out of which in 158 cases both BMA and BMB was performed simultaneously along with flow cytometry and cytogenetic study was done on some hematological malignancies and a correlation was done between all these procedures. Criteria of inclusion included the main indications for performing this procedure, the availability of full clinical data and patient consent. Result: In the present study, out of 158 cases with simultaneous BMA and BMB procedures were performed simultaneously showed 85.4% positive correlation between these two procedures. However, it was found that in cases of myelofibrosis, non-hodgkin’s lymphoma, myeloproliferative disorders and granulomas, involvement of marrow was detected better in bone marrow biopsies. And also simultaneous flowcytometry and cytogenetic analysis gives strong confirmatory diagnosis in hematological malignancies to know the origin, genetic alteration and minimal residual disease in follow –up cases for targeted therapy. Conclusion: This study concludes that in routine hematological practice BMA, BMB, Flow cytometry and Cytogenetic, all are complimentary to each other which should be done simultaneously for the better diagnostic and prognostic point of view.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84900469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. S. González, M. M. Corcuera, J. A. Durán, Melissa Rigesti Fertonani, Cécile Deschamps, Víctor Cortezo Vidal, Carmen Martín Carrera-Presas, L. A. D. L. Fuente, Víctor M . ParedesRodríguez
One of the most common medical emergencies that can occur in the appointment is an acute allergic reaction.The various forms of systemic allergicreactions are very well defined. These clinical situations are rarely described in the specialized literature and, in turn, poorly understood. Oral atopy comprises a wide variety of symptoms and signs sometimes difficult to differentiate from other adverse reactions. It is important to know the dental materials and other substances of stomatological use causing clinical diseases presented in oral mucosa; it corresponds to Stomatology Specialist his knowledge for diagnosis and successful treatment.
{"title":"Patient with Allergic Pathology: How to Handle It inDentistry.","authors":"C. S. González, M. M. Corcuera, J. A. Durán, Melissa Rigesti Fertonani, Cécile Deschamps, Víctor Cortezo Vidal, Carmen Martín Carrera-Presas, L. A. D. L. Fuente, Víctor M . ParedesRodríguez","doi":"10.9790/0853-1606036368","DOIUrl":"https://doi.org/10.9790/0853-1606036368","url":null,"abstract":"One of the most common medical emergencies that can occur in the appointment is an acute allergic reaction.The various forms of systemic allergicreactions are very well defined. These clinical situations are rarely described in the specialized literature and, in turn, poorly understood. Oral atopy comprises a wide variety of symptoms and signs sometimes difficult to differentiate from other adverse reactions. It is important to know the dental materials and other substances of stomatological use causing clinical diseases presented in oral mucosa; it corresponds to Stomatology Specialist his knowledge for diagnosis and successful treatment.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86851895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neha Joshi Tambake, Sumit Tambake, N. Gandhi, Y. Jadhav, K. Madhu, P. Burad
“Stamp technique” is a new technique for restoring class I and class II restorations with accurate occlusal topography. It was introduced mainly to restore Class I cavities and erosively damaged teeth. This technique is possible in teeth where preoperative anatomy of the tooth is intact and not destructed by carious lesion. A precise tooth‐like restoration with an accurate functional occlusion is obtained when the stamp technique is perfomed. This technique is also utilized for class II cavity restorations where marginal ridge is intact .This case report describes simple class I composite restoration using stamp technique. The purpose is to replicate occlusal anatomy by making a copy of the original unprepared tooth structure to get perfect anatomy in few minutes.
{"title":"Stamp technique -New perspective of Aesthetic Dentistry : A Case Report","authors":"Neha Joshi Tambake, Sumit Tambake, N. Gandhi, Y. Jadhav, K. Madhu, P. Burad","doi":"10.9790/0853-1606124951","DOIUrl":"https://doi.org/10.9790/0853-1606124951","url":null,"abstract":"“Stamp technique” is a new technique for restoring class I and class II restorations with accurate occlusal topography. It was introduced mainly to restore Class I cavities and erosively damaged teeth. This technique is possible in teeth where preoperative anatomy of the tooth is intact and not destructed by carious lesion. A precise tooth‐like restoration with an accurate functional occlusion is obtained when the stamp technique is perfomed. This technique is also utilized for class II cavity restorations where marginal ridge is intact .This case report describes simple class I composite restoration using stamp technique. The purpose is to replicate occlusal anatomy by making a copy of the original unprepared tooth structure to get perfect anatomy in few minutes.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73013686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Mortality due to early onset neonatal sepsis is much higher than late onset sepsis. Clinical manifestations of the early onset sepsis are non specific. Delay in treatment can lead to complications and death of the neonates. Objective: To detect the sensitivity, specificity and the positive predictive values of the gastric aspirate polymorphs and the acute phase reactants in relation with the blood cultures of the neonates with early onset sepsis. Materials And Methods: Study was conducted at a tertiary care center. 50 neonates were included in the study. Investigations like blood culture, CRP, micro ESR, band cell count and gastric aspirate polymorphs count was done. All the observations were recorded. The sensitivity, specificity, positive predictive value and the negative predictive values were calculated based on the observations. Results: In the present it was seen that 41.02% of the cases of neonatal sepsis with GA polymorphs have a sensitivity of 72.72 %, and a positive predictive value of 41.02 % with blood culture. In regard to neonatal sepsis, m-ESR was found to be correlated with a sensitivity and specificity of 54.54% and 67.85 % respectively. In cases of neonatal sepsis, sensitivity and specificity of band forms and blood culture is 78.57% and 75% respectively. Conclusion: The present study concludes that CRP and Band forms are useful in the early detection of early neonatal sepsis as both have high sensitivity, specificity and positive predictive values.
{"title":"Correlation of Gastric Aspirate Polymorphs And Acute Phase Reactants (M-Esr, Crp And Band Cell Count) With Blood Culture In Early onset Neonatal Sepsis – A Tertiary Care Study","authors":"Dr.Chandramohan Chekkali, Dr.Narahari Bapanpally, Dr.Ajay Mohan Varahala","doi":"10.9790/0853-1606133642","DOIUrl":"https://doi.org/10.9790/0853-1606133642","url":null,"abstract":"Introduction: Mortality due to early onset neonatal sepsis is much higher than late onset sepsis. Clinical manifestations of the early onset sepsis are non specific. Delay in treatment can lead to complications and death of the neonates. Objective: To detect the sensitivity, specificity and the positive predictive values of the gastric aspirate polymorphs and the acute phase reactants in relation with the blood cultures of the neonates with early onset sepsis. Materials And Methods: Study was conducted at a tertiary care center. 50 neonates were included in the study. Investigations like blood culture, CRP, micro ESR, band cell count and gastric aspirate polymorphs count was done. All the observations were recorded. The sensitivity, specificity, positive predictive value and the negative predictive values were calculated based on the observations. Results: In the present it was seen that 41.02% of the cases of neonatal sepsis with GA polymorphs have a sensitivity of 72.72 %, and a positive predictive value of 41.02 % with blood culture. In regard to neonatal sepsis, m-ESR was found to be correlated with a sensitivity and specificity of 54.54% and 67.85 % respectively. In cases of neonatal sepsis, sensitivity and specificity of band forms and blood culture is 78.57% and 75% respectively. Conclusion: The present study concludes that CRP and Band forms are useful in the early detection of early neonatal sepsis as both have high sensitivity, specificity and positive predictive values.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75515546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-01DOI: 10.9790/0853-16070298102
Dr.Abhishek Raman, Vidyapati, D. Prasad, D. Kumar
The term “Metabolic Syndrome” has become widely used since its inception in 2001 by the NCEPATPIII, the concept of “clustering” metabolic disorders and Cardiovascular Disease (CVD) risk factors has been discussed in the scientific literature for many decades. The highest recorded prevalence worldwide is in Native Americans, with nearly 60% of women ages 45–49 and 45% of men ages 45–49 meeting NCEP:ATPIII criteria. Prevalence of the metabolic syndrome ranges from about 11 to 41 per cent in different regions of India. The present study is a one year cross sectional study that aims to study the prevalence of metabolic syndrome in patients with acute myocardial infarction and to assess and analyse the prevalence of individual components of metabolic syndrome in patients with acute myocardial infarction & also its impact on the prognosis of patients with acute myocardial infarction during one week of in-hospital stay, admitted to Rajendra Institute of Medical Sciences , Ranchi. Data was collected during their hospital stay & descriptive statistical analysis ,.Test of proportion, Chi-square ( 2 ) Odds Ratio (OR) with 95% confidence limit were used for statistical analysis. The prevalence of metabolic syndrome in acute MI in our study (49.2 %). .The body mass index (BMI) of> 25 kg/m 2 was found to be present in 84.6 % of patients with metabolic syndrome. Serum Triglycerides was found to be higher in our study compared to other studies. The mean values of HDL-C and Waist Circumference (WC) were found to be lower in our study compared to other studies. .Among the components of metabolic syndrome, low HDL-C was the most prevalent component among Metabolic syndrome patients .Development of complications (heart failure, arrythmias, re-infarction and case mortality) was significantly higher in patients of metabolic syndrome compared to those without metabolic syndrome. Case mortality among patients of acute MI with metabolic syndrome was found to be 27.7 %.
{"title":"A Study of clinical and biochemical profile of Metabolic Syndrome in Acute myocardial Infarction","authors":"Dr.Abhishek Raman, Vidyapati, D. Prasad, D. Kumar","doi":"10.9790/0853-16070298102","DOIUrl":"https://doi.org/10.9790/0853-16070298102","url":null,"abstract":"The term “Metabolic Syndrome” has become widely used since its inception in 2001 by the NCEPATPIII, the concept of “clustering” metabolic disorders and Cardiovascular Disease (CVD) risk factors has been discussed in the scientific literature for many decades. The highest recorded prevalence worldwide is in Native Americans, with nearly 60% of women ages 45–49 and 45% of men ages 45–49 meeting NCEP:ATPIII criteria. Prevalence of the metabolic syndrome ranges from about 11 to 41 per cent in different regions of India. The present study is a one year cross sectional study that aims to study the prevalence of metabolic syndrome in patients with acute myocardial infarction and to assess and analyse the prevalence of individual components of metabolic syndrome in patients with acute myocardial infarction & also its impact on the prognosis of patients with acute myocardial infarction during one week of in-hospital stay, admitted to Rajendra Institute of Medical Sciences , Ranchi. Data was collected during their hospital stay & descriptive statistical analysis ,.Test of proportion, Chi-square ( 2 ) Odds Ratio (OR) with 95% confidence limit were used for statistical analysis. The prevalence of metabolic syndrome in acute MI in our study (49.2 %). .The body mass index (BMI) of> 25 kg/m 2 was found to be present in 84.6 % of patients with metabolic syndrome. Serum Triglycerides was found to be higher in our study compared to other studies. The mean values of HDL-C and Waist Circumference (WC) were found to be lower in our study compared to other studies. .Among the components of metabolic syndrome, low HDL-C was the most prevalent component among Metabolic syndrome patients .Development of complications (heart failure, arrythmias, re-infarction and case mortality) was significantly higher in patients of metabolic syndrome compared to those without metabolic syndrome. Case mortality among patients of acute MI with metabolic syndrome was found to be 27.7 %.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85508979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background and Aims: Elderly patients undergoing transurethral resection of prostate (TURP) surgeries are more prone to shivering induced peroperative complications which anaesthesiologists should aim to prevent rather than treat. The aim of the study is to evaluate the effect of Inj ramosetron on peroperative shivering and spinal hypotension in patients undergoing transurethral resection of prostate under subarachnoid block (SAB). Method: In this prospective doubleblind, randomized, comparative study, a total of 60 patients belonging to American Society of Anaesthesiologist (ASA) I and II physical status between the age group of 60 to 85 years, scheduled for elective TURP surgeries under spinal anaesthesia were selected. The patients were randomly allocated into one of the two groups of thirty patients each. For patients allocated in Group S, 2 ml of normal saline and in group R, 0.3 mg ramosetron (2ml) was intravenously injected 5 min before the SAB. The primary outcome was the reduction in the incidence of shivering by pretreatment with ramosetron. The maximum change in the mean arterial pressure from the base line was the secondary outcome. Using normal approximation to binominal distribution the sample size was calculated. Data collection such as sensory block level, haemodynamic parameters, rectal temperature and grades of shivering were performed at 10 minute intervals. Results: Data among the groups were compared using Analysis of Variance (ANOVA) test in Matrix Laboratory (MATLAB) environment. Incidence and intensity of shivering and hypotension were significantly less in R group than the S group (P<0.001) and (P<0.001) respectively. There was no significant difference with respect to heart rate, saturation of peripheral oxygen (SPO2), sensory block level achieved and reduction in the core temperature between the two groups. Conclusion: We conclude that pretreatment with intravenous ramosetron 0.3mg given before spinal anaesthesia in geriatric patients undergoing TURP surgeries effectively reduces the incidence and intensity of shivering and hypotension associated with spinal anaesthesia.
{"title":"Effect of Ramosetron on Peroperative Shivering and Hypotension in Patients Undergoing Transurethral Resection of Prostate Surgeries under Spinal Anaesthesia. A Prospective, Double Blind, Randomized, Comparative Study.","authors":"B. Vasanthi, Dr.T.Sadagopan. Md.Da","doi":"10.9790/0853-1606120309","DOIUrl":"https://doi.org/10.9790/0853-1606120309","url":null,"abstract":"Background and Aims: Elderly patients undergoing transurethral resection of prostate (TURP) surgeries are more prone to shivering induced peroperative complications which anaesthesiologists should aim to prevent rather than treat. The aim of the study is to evaluate the effect of Inj ramosetron on peroperative shivering and spinal hypotension in patients undergoing transurethral resection of prostate under subarachnoid block (SAB). Method: In this prospective doubleblind, randomized, comparative study, a total of 60 patients belonging to American Society of Anaesthesiologist (ASA) I and II physical status between the age group of 60 to 85 years, scheduled for elective TURP surgeries under spinal anaesthesia were selected. The patients were randomly allocated into one of the two groups of thirty patients each. For patients allocated in Group S, 2 ml of normal saline and in group R, 0.3 mg ramosetron (2ml) was intravenously injected 5 min before the SAB. The primary outcome was the reduction in the incidence of shivering by pretreatment with ramosetron. The maximum change in the mean arterial pressure from the base line was the secondary outcome. Using normal approximation to binominal distribution the sample size was calculated. Data collection such as sensory block level, haemodynamic parameters, rectal temperature and grades of shivering were performed at 10 minute intervals. Results: Data among the groups were compared using Analysis of Variance (ANOVA) test in Matrix Laboratory (MATLAB) environment. Incidence and intensity of shivering and hypotension were significantly less in R group than the S group (P<0.001) and (P<0.001) respectively. There was no significant difference with respect to heart rate, saturation of peripheral oxygen (SPO2), sensory block level achieved and reduction in the core temperature between the two groups. Conclusion: We conclude that pretreatment with intravenous ramosetron 0.3mg given before spinal anaesthesia in geriatric patients undergoing TURP surgeries effectively reduces the incidence and intensity of shivering and hypotension associated with spinal anaesthesia.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90649328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The clinical appearance of leg ulcers is an important factor in the clinical assessment of healing progress. Digital imaging techniques, being objective and reproducible, have advantages over human assessment of wounds. In this cross-sectional, prospective study, conducted in a teaching hospital in Western India, images of 45 chronic leg ulcers were obtained using a digital camera to objectively analyze ulcer images with the help a software system. The clinical state of ulcers was documented by a wound score by the first observer and the readings of Red-Yellow-Black-Pink components of the ulcer-images were taken using ImageJ software by the second observer. The data were analyzed using appropriate statistical tests. The leg ulcers were classified clinically into four categories: Healing, Inflamed, Slough and Necrotic, as per Applied Wound Management assessment tool. The clinical score and Red-Yellow-Black-Pink colour analysis using ImageJ were obtained. The inter-rater analysis using linear weighted kappa (K) was highly significant (K=0.833; 95% CI: 0.709 to 0.957), indicating excellent agreement. The results from this pilot study suggest that digital imaging technique has the potential to objectively process digital images of chronic ulcers.
{"title":"Objective Image-based Analysis of Leg ulcers - A Pilot Study","authors":"D. Mogre, S. Kartikeyan","doi":"10.9790/0853-1607020711","DOIUrl":"https://doi.org/10.9790/0853-1607020711","url":null,"abstract":"The clinical appearance of leg ulcers is an important factor in the clinical assessment of healing progress. Digital imaging techniques, being objective and reproducible, have advantages over human assessment of wounds. In this cross-sectional, prospective study, conducted in a teaching hospital in Western India, images of 45 chronic leg ulcers were obtained using a digital camera to objectively analyze ulcer images with the help a software system. The clinical state of ulcers was documented by a wound score by the first observer and the readings of Red-Yellow-Black-Pink components of the ulcer-images were taken using ImageJ software by the second observer. The data were analyzed using appropriate statistical tests. The leg ulcers were classified clinically into four categories: Healing, Inflamed, Slough and Necrotic, as per Applied Wound Management assessment tool. The clinical score and Red-Yellow-Black-Pink colour analysis using ImageJ were obtained. The inter-rater analysis using linear weighted kappa (K) was highly significant (K=0.833; 95% CI: 0.709 to 0.957), indicating excellent agreement. The results from this pilot study suggest that digital imaging technique has the potential to objectively process digital images of chronic ulcers.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90149247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis of immunohistochemical expression of CD10 in the malignant lesions of prostate","authors":"Saranya Dhanarasu","doi":"10.9790/0853-1607017882","DOIUrl":"https://doi.org/10.9790/0853-1607017882","url":null,"abstract":"","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89066773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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