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Case Report: Mandibular Second Premolar, A Morphological Ingruity 病例报告:下颌第二前磨牙,形态不完整
Pub Date : 2017-07-01 DOI: 10.9790/0853-160603118120
Mridusmita Mukherjee, A. Bhattacharyya
The root canal is a complex system of finely tuned and synchronized small tributaries present along the body of tooth dentine. Therefore, knowledge of pulp anatomy is essential for endodontic treatment success, as lack of sound knowledge of the pulp anatomy can contribute to treatment failure. With the advancement of technological aids and numerous research have laid the foundation of multi rooted teeth or canals as the rule rather than exception. As such, bifurcating canals, multiple foramina, fins, deltas, loops, cul-de-sacs, C-shaped canals and accessory canals are commonly encountered in most teeth. So, accurate diagnosis followed by location, cleaning and shaping and finally obturation of such variations of canals is important as it determines the prospect of success of endodontic therapy.
根管是一个复杂的系统,由沿着牙本质的小支流组成。因此,牙髓解剖知识对于根管治疗的成功至关重要,因为缺乏牙髓解剖知识会导致治疗失败。随着技术的进步和大量的研究已经奠定了多根牙或多根根管的基础,而不是例外。因此,分叉根管、多孔根管、鳍状根管、三角根管、环状根管、死角根管、c形根管和副根管在大多数牙齿中都很常见。因此,准确的诊断,定位,清洁,整形,最后封闭这些管的变化是非常重要的,因为它决定了根管治疗成功的前景。
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引用次数: 0
Knowledge, Attitude and Willingness for Eye Donation in General Population of Odisha inEastern India 印度东部奥里萨邦普通民众对眼部捐赠的知识、态度和意愿
Pub Date : 2017-07-01 DOI: 10.9790/0853-1607010106
Suchitra Panigrahi, B. Rath, R. Sahu, S. Rath, S. Sethi, Kasturi Mahapatra
Aim: To assess the knowledge,attitude and willingness of general population towards eye donation which includes patients and their attendants attending the outpatient department of a tertiary care medical college hospital of southern Orissa, Eastern India. Materials and methods: 452 participants were administered a pretested semi-structured questionnaire. Chisquare test was used to determine the factors associated with willingness towards eye donation. Data was analysed using Graphpad prism version 7.0 Results: In this study 247(54.6%) participants were willing to pledge for eye donation ,there was significant association of willingness to donate eyes among males159 (64.1%) , among participants below 40 years of age175 (75.2%),participants with higher education status146 (82.9%) and urban population147 (70.6%) .Perceived reasons among 205 (45.3%) who were not willing to pledge were,137(66.8%) need more information regarding eye donation,52(25.3%) thought family may not allow for eye donation and 16(7.8%) participants did not want to pledge due to religious disbelief.Media played a major role in creating awareness for eye donation. Conclusion:Multipronged innovative strategies should be adopted to increase the awareness regarding eye donation in less educated and rural population.
目的:了解印度东部奥里萨邦南部某三级专科医院门诊患者及其护理人员对眼部捐赠的知识、态度和意愿。材料与方法:对452名参与者进行预测半结构化问卷调查。使用Chisquare检验确定与眼部捐赠意愿相关的因素。使用Graphpad prism 7.0版本进行数据分析。在本研究中,247名(54.6%)参与者愿意捐献眼睛,其中男性捐献意愿显著相关159人(64.1%);40岁以下175人(75.2%),高学历146人(82.9%),城市人口147人(70.6%)。205人(45.3%)不愿意捐眼的原因为:需要了解更多有关捐眼的信息137人(66.8%),认为家人可能不允许捐眼的52人(25.3%),不愿意捐眼的16人(7.8%)。媒体在提高人们对眼部捐赠的认识方面发挥了重要作用。结论:应采取多管齐下的创新策略,提高教育程度较低和农村人群的眼部捐赠意识。
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引用次数: 5
Prevalence of Dengue Virus Infection Among Febrile Outpatients Attending University of Maiduguri Teaching Hospital in Borno State, Nigeria 尼日利亚博尔诺州迈杜古里大学教学医院发热门诊患者登革热病毒感染流行情况
Pub Date : 2017-07-01 DOI: 10.9790/0853-160603155159
T. M. Hamisu, A. Yuguda, M. Abubakar, Y. Shettima, M. Maina, M. Y. Zanna, S. S. Baba, A. Andrew, i.C. Terhemen
Dengue fever is a zoonotic arthropod-borne viral disease caused by Dengue fever virus (DENV) of the Genus Flavivirus and the FamilyFlaviviridaethat is endemic in Africa and beyond. The illness could be fatal especially among children and depleted patients.This study was designed to diagnose recentDengue virus infectionsamong febrile patients attending University of Maiduguri Teaching Hospital using ELISA kits for the detection of DENV IgM antibodies and NS1 antigens. Ninety one (91) venous blood samples were randomly collected from patients attending Maiduguri Teaching Hospital for malaria test between January and May, 2016. The samples were analysed using Enzyme Linked Immunosorbent Assays for dengue virus IgM antibodies (manufactured by Inverness Innovations Australia Pty Ltd ) and for Dengue virus NS1antigens (manufactured by Bio-Rad, France). The results showed a prevalence rate of 37.4% for DENV IgM antibodies and 9.9% for DENV NS1 antigens, with 3.3% of the subjects testingpositive for both IgM and NS1 antigen. Females were observed to have higher IgM prevalence rate of 41% and males showed higher NS1 antigen prevalence rate of 11.1%. The highest prevalence rate of 76.9% was recorded for IgM in the age bracket of 1-14 years. Samples from urban areas have the highest IgM antibodyprevalence rate of 41.4%, however, rural dwellers have the highest NS1 antigen prevalence rate of 11.3%. The presenting complaint with the highest IgM prevalence rate of 50% was headache + fever + nausea, while headache only had the highest NS1 antigen of 22.2%. The highest prevalence rate of 47.4% for IgM and 50% for NS1 antigen were recorded in March and May, 2016 respectively. This study therefore showed a high prevalence of IgM to Dengue fever virus indicating its circulation among febrile patients attending University of Maiduguri Teaching Hospital. Due to the probable misdiagnosis and subsequent treatment of dengue fever with other diseases such as malaria, dengue fever is shown to be prevalent in the study area. It is therefore recommended that febrile patients attending Maiduguri Teaching Hospital should be tested for dengue fever virus.
登革热是由黄病毒属和黄病毒科登革热病毒(DENV)引起的一种人畜共患节肢动物传播的病毒性疾病,在非洲及其他地区流行。这种疾病可能是致命的,特别是在儿童和虚弱的病人中。本研究旨在利用ELISA试剂盒检测DENV IgM抗体和NS1抗原,诊断迈杜古里大学教学医院发热患者近期登革热病毒感染。2016年1月至5月在迈杜古里教学医院随机抽取91份静脉血进行疟疾检测。使用酶联免疫吸附法对样本进行分析,检测登革病毒IgM抗体(由Inverness Innovations Australia Pty Ltd生产)和登革病毒ns1抗原(由Bio-Rad,法国生产)。结果显示,登革热病毒IgM抗体阳性率为37.4%,NS1抗原阳性率为9.9%,其中IgM和NS1抗原均阳性的比例为3.3%。女性IgM患病率为41%,男性NS1抗原患病率为11.1%。1 ~ 14岁IgM患病率最高,为76.9%。城市地区IgM抗体患病率最高,为41.4%,而农村地区NS1抗原患病率最高,为11.3%。IgM患病率最高的主诉为头痛+发热+恶心(50%),而头痛的NS1抗原最高(22.2%)。2016年3月和5月IgM和NS1抗原感染率最高,分别为47.4%和50%。因此,这项研究表明登革热病毒IgM的高流行率表明其在迈杜古里大学教学医院的发热患者中传播。由于登革热与疟疾等其他疾病的误诊和后续治疗可能存在,因此登革热在研究地区普遍存在。因此,建议在迈杜古里教学医院就诊的发热病人应接受登革热病毒检测。
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引用次数: 4
Cognitive impairment in patients with epilepsy: A case control study at a tertiary level hospital in India 癫痫患者的认知障碍:印度一家三级医院的病例对照研究
Pub Date : 2017-07-01 DOI: 10.9790/0853-160702103106
Dr.Ravindra B. Narod, Dr.Rathod Rahul Narayanrao, Dr.Sayali V. Bhambar, Dr.Sapna Anjutagi, Dr.Smit U. Janrao, Dr.Pranav Deore
Introduction: Cognition is defined as the capacity of the brain to process information accurately leading to an adaptive behaviour. This study aims at understanding the decline in cognition in patients diagnosed with epilepsy in India using a standardized cognition scale. Methodology: We did a case control study in the Department of Psychiatry, Government Medical College, Miraj in which all patients with a diagnosis of epilepsy from October 2016 till February 2017 were included. Patients were tested for cognitive impairment using the PGI Memory scale (PGIMS). Controls were included from the population sample of non teaching staff of college. We noted age, gender, handedness, and education levels and clinical information. All cases and controls were tested for cognitive functioning using PGIMS. The data was analysed descriptively and then the cases and controls were compared using the unpaired Student’s t test, with p value less than 0.05 being statistically significant. Results:We enrolled 60 patients diagnosed with epilepsy and same number of healthy controls from the same insitution. Average age of the patients with epilepsy was 43.7±2.4 years and that of controls was 48.1±3.6 years. The difference between the cases and controls was found to be statistically highly significant in cognition tests like recent memory, remote memory, immediate recall and visual retention. On cognitive tests like attention and concentration, retention of dissimilar pairs, mental balance the difference between the groups was found to be statistically significant. Conclusions: Findings of our study demonstrates that patients with epilepsy shuould be routinely tested for cognitive decline.
导读:认知被定义为大脑准确处理信息并导致适应性行为的能力。本研究旨在了解认知能力下降的患者诊断癫痫在印度使用标准化的认知量表。方法:我们在Miraj政府医学院精神学系进行了一项病例对照研究,其中包括2016年10月至2017年2月期间诊断为癫痫的所有患者。使用PGI记忆量表(PGIMS)对患者进行认知障碍测试。对照从高校非教学人员的总体样本中选取。我们记录了年龄、性别、惯用手、教育水平和临床信息。使用PGIMS对所有病例和对照组进行认知功能测试。对数据进行描述性分析,然后用unpaired Student’s t检验比较病例和对照组,p值小于0.05为有统计学意义。结果:我们从同一机构招募了60名癫痫患者和相同数量的健康对照。癫痫患者平均年龄为43.7±2.4岁,对照组平均年龄为48.1±3.6岁。研究发现,在近期记忆、远程记忆、即时回忆和视觉保留等认知测试中,病例和对照组之间的差异在统计上非常显著。在认知测试中,比如注意力和注意力,对不同组合的记忆,心理平衡,两组之间的差异在统计上是显著的。结论:我们的研究结果表明癫痫患者应该进行常规的认知能力下降测试。
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引用次数: 0
Fixation of Subtrochantric Fractures Using Distal Femoral Locking Compression Plate of Contralateral Side 对侧股骨远端锁定加压钢板固定粗隆下骨折
Pub Date : 2017-07-01 DOI: 10.9790/0853-1607013945
Roel Langshong, B. Punithavasanthan, Pheiroijam Bhupes, S. Singh, Rajkumar Debbarma, P. S. Prashanth, P. rai, Shams Gulrez, Dilip Soring, Temjen sunep
Introduction: Different implants are available to internally fix subtrochantric fracture of femur, due to anatomical & biomechanical reasons, the sub-trochanteric femoral fracture still a challenge for Orthopaedic Surgeons Objective: The purpose of this study was to evaluate the outcome in early treatment of subtrochanteric fractures of femur with distal femoral locking compression plate of contralateral side. Methods: Thirty patients were included in this study. Sixteen patients (53.3%) had AO type 32B fracture, while nine patients (30%) and five patients (16.6%) were classified as AO type 32A and 32C respectively. Road traffic accidents accounted for 21 patients (70%). Mean follow-ups were 11 ±6 months (range 6 to 19 months). 27 fractures (90%) achieved union, average union time in 14.5 weeks Ranging from 10 weeks to 20 weeks. while three patients (10%) had complications. In one patient the plate had broken, one had broken screw and nonunion of the fracture. At the end of the follow-ups, 29 patients (96.6%) were community ambulators.The Modified Harris hip score (MMHS) was used to evaluate the functional outcome of surgery Conclusion: We conclude that distal femoral locking compression plate of contra lateral side is as effective as PF-LCP and is an effective alternative treatment for subtrochanteric fractures when properly performed.
导读:股骨粗隆下骨折的内固定有不同的植入物,但由于解剖学和生物力学的原因,股骨粗隆下骨折的内固定仍然是骨科医生面临的一个挑战。目的:本研究的目的是评估对侧股骨远端锁定加压钢板早期治疗股骨粗隆下骨折的效果。方法:选取30例患者作为研究对象。AO 32B型骨折16例(53.3%),AO 32A型9例(30%),AO 32C型5例(16.6%)。道路交通事故占21例(70%)。平均随访11±6个月(6 ~ 19个月)。27例骨折愈合(90%),平均愈合时间14.5周,愈合时间从10周到20周不等。3例(10%)出现并发症。1例患者钢板断裂,1例患者螺钉断裂,骨折不愈合。随访结束时,29例患者(96.6%)使用社区救护车。结论:对侧股骨远端锁定加压钢板与PF-LCP一样有效,如果操作得当,是转子下骨折的有效替代治疗方法。
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引用次数: 0
Alteration of Salivary Calcium and Statherin Levels in Patients with Gingivitis and Periodontitis 牙龈炎和牙周炎患者唾液钙和钙素水平的改变
Pub Date : 2017-07-01 DOI: 10.9790/0853-1607011719
A. Primasari, Yumi Lindawati, Irma Ervina
‘Salivary proteins have an important influence in tooth enamel remineralize associated with calcium hydroxyapatite. Statherin is the most powerful protein that binds calcium hydroxyapatite in saliva than other calcium-binding protein. Infection in gingiva and periodontal caused alteration of statherin and calcium levels. Therefore, researchers wanted to determine and to compare salivary statherin and calcium levels in gingivitis and periodontitic mainly on the Indonesian as an initial data to explore the influence of statherin and calcium in patients with gingivitis and periodontitic. By spitting method, 54 samples of whole saliva taken from gingivitis and periodontitic patients ; aged 20-50 years, doesn’t have antibiotic treatment in 3 months, no smoking, no areca chewing, not pregnant, lactating or menstruating. Statherin level measurement using ELISA method and calcium level by spectrophotometry method. Results showed mean concentration of statherin for gingivitis is 1,79 ug / ml, while periodontitics is 2,73 ug / ml. Mean concentration for calcium in gingivitis saliva is 5,31 mmol/l, and periodontitic is 0,18 mmol/l. The Spearman’s correlation test showed 2 different results from 2 groups of samples. Gingivitis group showed there is no correlation between calsium and statherin in saliva (p>0,01), but periodontitic group showed there is significant correlation between calcium and statherin in saliva (p<0,05). The result showed that, although both are the result of salivary excretion (statherin and calcium), it turns out to different infection, showed different result. These results suggest there is a different mechanism in both infection.
唾液蛋白对牙釉质羟基磷灰石钙再矿化有重要影响。石蜡蛋白是结合唾液中羟基磷灰石钙的最强蛋白。牙龈及牙周感染可引起凝血素及钙水平的改变。因此,研究人员希望确定并比较牙龈炎和牙周病患者唾液中施他汀素和钙的水平,主要以印度尼西亚人为研究对象,作为初步数据,探讨施他汀素和钙对牙龈炎和牙周病患者的影响。采用吐痰法采集牙龈炎、牙周病患者全唾液54份;年龄20-50岁,3个月内没有抗生素治疗,不吸烟,不嚼槟榔,没有怀孕、哺乳期、月经。酶联免疫吸附法测定施他汀素水平,分光光度法测定钙水平。结果牙龈炎和牙周病患者唾液中施他汀素平均浓度分别为1.79 ug / ml和2.73 ug / ml,牙龈炎和牙周病患者唾液中钙的平均浓度分别为5.31 mmol/l和0.18 mmol/l。Spearman相关检验从两组样本中得出了两种不同的结果。牙龈炎组患者唾液中钙含量与statherin含量无相关性(p> 0.01),牙周病组患者唾液中钙含量与statherin含量有显著相关性(p< 0.05)。结果表明,虽然两者都是唾液排泄的结果(凝血素和钙),但结果表明,不同的感染,表现出不同的结果。这些结果表明,在这两种感染中存在不同的机制。
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引用次数: 1
A Clinico Histopathological Study of Childhood Leprosy 儿童麻风的临床组织病理学研究
Pub Date : 2017-07-01 DOI: 10.9790/0853-1607018390
D. Rao, Dr.G. Leelavathi, Dr. G. Purnima
Background: Leprosy is one of the oldest diseases known to mankind and is still associated with stigma. A high child proportion signifies active and recent transmission of the disease. Aim: To know the proportion of children in newly detected leprosy patients and their clinico histopathological categorisation. Methodology: This was a retrospective analysis of all leprosy patients less than 16 years of age registered at the Leprosy Clinic of GGH, Vijayawada from January2015-June2016. Results: Proportion of children among newly diagnosed leprosy patients was 9.2% .Majority of patients belonged to age group of 13 to 16 years(48%), with male preponderance. 24% patients gave family history of leprosy. 40% of patients belonged to PB type, 60% MB type. Slit skin smear was positive in 20%. According to clinical characteristics, majority of patients belonged to BT(52%) followed by TT(32%). According to histopathological characteristics majority of patients belonged to BT(48%) followed by TT(36%).Clinico Histopathological correlation in LL Hansen’s is 100%, in BT 76%.Type I reaction occurred in 2 patients(8%).Deformities were observed in 8% patients. Conclusion: Despite statistical elimination of leprosy, childhood leprosy still remains a public health problem. Early detection, treatment and contact tracing are important for reducing the burden of leprosy in the community.
背景:麻风病是人类已知的最古老的疾病之一,仍然与耻辱有关。儿童比例高表明该疾病的活跃和最近的传播。目的:了解儿童在新发麻风患者中的比例及其临床病理分型。方法:回顾性分析2015年1月至2016年6月在维杰亚瓦达GGH麻风诊所登记的所有16岁以下麻风患者。结果:新诊断麻风患者中儿童所占比例为9.2%,以13 ~ 16岁年龄组(48%)居多,男性居多。24%的患者有麻风病家族史。PB型占40%,MB型占60%。切口皮肤涂片阳性占20%。从临床特征来看,大部分患者属于BT(52%),其次是TT(32%)。根据组织病理学特征,大多数患者属于BT(48%),其次是TT(36%)。临床组织病理学相关性为100%,BT为76%。2例(8%)发生I型反应。8%的患者出现畸形。结论:尽管统计上已经消除了麻风病,但儿童麻风病仍然是一个公共卫生问题。早期发现、治疗和接触者追踪对于减轻社区麻风病负担非常重要。
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引用次数: 1
Patient with Allergic Pathology: How to Handle It inDentistry. 过敏病理患者:如何处理。
Pub Date : 2017-07-01 DOI: 10.9790/0853-1606036368
C. S. González, M. M. Corcuera, J. A. Durán, Melissa Rigesti Fertonani, Cécile Deschamps, Víctor Cortezo Vidal, Carmen Martín Carrera-Presas, L. A. D. L. Fuente, Víctor M . ParedesRodríguez
One of the most common medical emergencies that can occur in the appointment is an acute allergic reaction.The various forms of systemic allergicreactions are very well defined. These clinical situations are rarely described in the specialized literature and, in turn, poorly understood. Oral atopy comprises a wide variety of symptoms and signs sometimes difficult to differentiate from other adverse reactions. It is important to know the dental materials and other substances of stomatological use causing clinical diseases presented in oral mucosa; it corresponds to Stomatology Specialist his knowledge for diagnosis and successful treatment.
最常见的医疗紧急情况之一可能发生在预约是急性过敏反应。各种形式的全身过敏反应是非常明确的。这些临床情况很少在专业文献中描述,反过来,也很少被理解。口腔特应性包括各种各样的症状和体征,有时难以与其他不良反应区分。重要的是要了解口腔材料和其他口腔使用物质引起的口腔黏膜临床疾病;它对应于口腔专家他的诊断和成功治疗的知识。
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引用次数: 0
Initiation of JE Vaccination-An Experience: A Mixed Method Study In A Tertiary Care Center of West Bengal, India 开始接种乙脑疫苗-经验:在印度西孟加拉邦三级保健中心的混合方法研究
Pub Date : 2017-07-01 DOI: 10.9790/0853-1607012026
A. Samanta, DrJadav Chandra Sardar, P. Sengupta, A. Chatterjee, S. Lahiri
Background:JE is an emerging public health problem in India.JE vaccine has been incorporated in the National Immunization Schedule in India following mass vaccination. Objectives:To explore the experiences gathered during mass vaccination period in a tertiary care center. Methodology:A mixed method approach consisting of a cross-sectional survey and qualitative study was adopted. The qualitative study was included to obtain more in-depth understanding of the experiences and perspectives of frontline workers and the team leader in form of in depth interview of LMO of satellite center and FGDamong all PHNS involved in the activity. Result:Among 2437 vaccinees surveyed, majority belonged to 1-5 years age group followed by 6-10 years.Only half of the caregivers of surveyed population knew the purpose of vaccination and 6%perceived that the vaccine prevents ‘Dengue’. No AEFI was reported during and one months following the mass vaccination.Qualitative approach revealed huge enthusiasm among the people about the vaccine, lack of staff and space to cater large age group section and inappropriate rush during the vaccination sessions and impairment of routine vaccination during the mass vaccination period. Conclusion:Thoroughly planned systematic IEC activities and prior deployment and orientation of staffs are pre requisites for conducting suchlarge scale mass vaccination programme.
背景:乙脑是印度一个新出现的公共卫生问题。在大规模接种疫苗后,印度已将乙脑疫苗纳入国家免疫计划。目的:探讨某三级保健中心在大规模疫苗接种期间收集的经验。研究方法:采用横断面调查与定性研究相结合的混合方法。在所有参与活动的PHNS中,通过对卫星中心LMO和fgdv的深度访谈,纳入定性研究,以更深入地了解一线工作人员和组长的经验和观点。结果:2437名接种者以1 ~ 5岁年龄组居多,6 ~ 10岁次之。被调查人群中只有一半的护理人员知道接种疫苗的目的,6%的人认为疫苗可以预防“登革热”。在大规模疫苗接种期间和接种后1个月内未报告急性呼吸道感染。定性分析表明,群众对疫苗接种热情高涨,人员和空间不足以满足大年龄组段的需求,接种期间不适当的匆忙接种,大规模接种期间常规接种受到损害。结论:开展如此大规模的大规模疫苗接种规划的先决条件是周密计划的系统的信息、教育和宣传活动,以及工作人员的事先部署和定向。
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引用次数: 0
Bone Marrow Aspiration Evaluation in Clinical Management of Anemia Among Low Socioeconomic Group In A Tertiary Care Hospital. 某三级医院低社会经济人群贫血临床管理中的骨髓抽吸评价
Pub Date : 2017-07-01 DOI: 10.9790/0853-1607028997
J. JohnsyMerla, J. SureshDurai, K. Shantaraman
Bone marrow aspiration (BMA) is a relatively safe invasive procedure by which representative sample of bone marrow is obtained through a needle aspiration for diagnostic evaluations. A total of 331 cases of anemia were profiled during the study period. The age range of patients were from 10 to 81 years. The majority of the subjects was in the adolescent age group of 10 – 19 years(20.54%). A complete blood count and peripheral smear examination in these cases revealed 125(37.76%) microcytic hypochromic anemia followed by 116(35.05%) Dimorphic anemia,23(6.95%)Pancytopenia, 23(6.95%)leukemia,31 cases (9.37%) macrocytic anemia,2 haemolytic anemia and 11(3.32%) were normocytic. These cases were further evaluated with bone marrow examination bone-marrow aspiration revealed 88 (26.59%) erythroid hyperplasia with micronormoblastic and macronormoblastic maturation(Combined deficiency),56 ( 16.92%) micronormoblastic maturation, 38 (11.48%) megaloblastic maturation, 23 ( 6.95%) Leukemia, Plasma cell myeloma 7(2.11%), lymphoma 6 (1.81%), hypoplastic marrow 5 (1.51%), haemophagocytic Lymphohistiocytosis 4 (1.21%),3 (0.91%) myelodysplastic syndrome, 2 (0.60%)cases of idiopathic thrombocytopenic purpura.In 22 (6.65%) cases the marrow was reactive. The age, sex, peripheral smear study, bone marrow aspiration study and diagnosis were collated and statistically analyzed. A definite diagnosis of plasma cell myeloma,lymphoma and myelodysplastic syndrome was possible only with bone marrow evaluation. In our study,in 77 % of cases a definite diagnosis of cause of anemia was arrived after bone marrow evaluation. 50% of cases were diagnosed with megaloblastic anemia indicating an underlying B12 and folate deficiency.
骨髓穿刺(BMA)是一种相对安全的侵入性手术,通过针吸获得有代表性的骨髓样本进行诊断评估。在研究期间,共记录了331例贫血病例。患者年龄10 ~ 81岁。调查对象以10 ~ 19岁青少年为主(20.54%)。全血细胞计数及外周血涂片检查显示:小细胞性低色素贫血125例(37.76%),二形性贫血116例(35.05%),全血细胞减少症23例(6.95%),白血病23例(6.95%),巨细胞性贫血31例(9.37%),溶血性贫血2例(3.32%),正常细胞性贫血11例(3.32%)。进一步行骨髓检查,骨髓穿刺示红系增生伴微母细胞和巨母细胞成熟88例(26.59%),微母细胞成熟56例(16.92%),巨母细胞成熟38例(11.48%),白血病23例(6.95%),浆细胞骨髓瘤7例(2.11%),淋巴瘤6例(1.81%),骨髓发育不良5例(1.51%),噬血细胞淋巴组织细胞增多症4例(1.21%),骨髓增生异常综合征3例(0.91%),骨髓增生异常综合征3例(0.91%)。特发性血小板减少性紫癜2例(0.60%)。22例(6.65%)患者骨髓有反应。对年龄、性别、外周血涂片检查、骨髓穿刺检查及诊断进行统计分析。只有骨髓评估才能明确诊断浆细胞骨髓瘤、淋巴瘤和骨髓增生异常综合征。在我们的研究中,有77%的病例在骨髓评估后明确诊断出贫血的原因。50%的病例被诊断为巨幼细胞性贫血,表明潜在的B12和叶酸缺乏。
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引用次数: 1
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