The preliminary phytochemical investigation was performed on methanolic and hydroalcoholic extract of Datura fastuosa (syn: Datura metel) revealed the presence of alkaloids, tannins, cardiac glycosides, flavonoids, carbohydrates, amino acids and phenolic compounds, while, phytochemical analysis of Datura stramonium showed that it contained alkaloids, saponins, tannins, steroids, flavonoids, phenols and glycosides. The previous pharmacological studies of Datura fastuosa showed that it possessed antimicrobial insecticidal, antidiabetic, cytotoxic, antioxidant, antiinflammatory, analgesic, antipyretic, neurological, wound healing, reproductive and antispasmodic, while Datura stramonium exerted Antiepileptic, Anti-asthmatic, analgesic, antioxidant, antimicrobial, insecticidal, repellent and organophosphate protective effects. The current review highlights the chemical constituents and pharmacological effects of Datura fastuosa and Datura stramonium.
{"title":"Medical importance of Datura fastuosa (syn: Datura metel) and Datura stramonium - A review","authors":"A. Al-Snafi","doi":"10.9790/3013-0702014358","DOIUrl":"https://doi.org/10.9790/3013-0702014358","url":null,"abstract":"The preliminary phytochemical investigation was performed on methanolic and hydroalcoholic extract of Datura fastuosa (syn: Datura metel) revealed the presence of alkaloids, tannins, cardiac glycosides, flavonoids, carbohydrates, amino acids and phenolic compounds, while, phytochemical analysis of Datura stramonium showed that it contained alkaloids, saponins, tannins, steroids, flavonoids, phenols and glycosides. The previous pharmacological studies of Datura fastuosa showed that it possessed antimicrobial insecticidal, antidiabetic, cytotoxic, antioxidant, antiinflammatory, analgesic, antipyretic, neurological, wound healing, reproductive and antispasmodic, while Datura stramonium exerted Antiepileptic, Anti-asthmatic, analgesic, antioxidant, antimicrobial, insecticidal, repellent and organophosphate protective effects. The current review highlights the chemical constituents and pharmacological effects of Datura fastuosa and Datura stramonium.","PeriodicalId":14540,"journal":{"name":"IOSR Journal of Pharmacy","volume":"71 1","pages":"43-58"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81135125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aziz A. Al-Sohaimi, Hasan S. Al-Ghamdi, Abdulrahman Alghamdi, A. Alghamdi, F. Alzahrani, A. A. Alghamdi, K. Alghamdi
The term "dermal melanocytic nevi" includes a group of clinically and histopathologically distinct subtypes, including Miescher’s nevus, flat nevus, and Unna’s nevus. Flat nevi are the most common clinical type. Miescher’s and Unna’s nevi have different clinical and histopathological features, making them easily distinguishable. We present a case of an Unna’s nevus in the posterior of the scalp with unusual localization.
{"title":"Unna nevus of the scalp: Unusual clinical presentation","authors":"Aziz A. Al-Sohaimi, Hasan S. Al-Ghamdi, Abdulrahman Alghamdi, A. Alghamdi, F. Alzahrani, A. A. Alghamdi, K. Alghamdi","doi":"10.9790/3013-0701013941","DOIUrl":"https://doi.org/10.9790/3013-0701013941","url":null,"abstract":"The term \"dermal melanocytic nevi\" includes a group of clinically and histopathologically distinct subtypes, including Miescher’s nevus, flat nevus, and Unna’s nevus. Flat nevi are the most common clinical type. Miescher’s and Unna’s nevi have different clinical and histopathological features, making them easily distinguishable. We present a case of an Unna’s nevus in the posterior of the scalp with unusual localization.","PeriodicalId":14540,"journal":{"name":"IOSR Journal of Pharmacy","volume":"2008 1","pages":"37-41"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86224223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The previous studies revealed that Equisetum arvense contained alkaloids, carbohydrate, proteins and amino acids, phytosterols, saponins, sterols, ascorbic acid, silicic acid, phenol , tannin, flavonoids, triterpenoids, volatile oils and many other biological active constituents. The pharmacological studies showed that it possessed antioxidant, anticancer, antimicrobial, smooth muscle relaxant effects of the vessels and ileum, anticonvulsant, sedative, anti-anxiety, dermatological immunological, antinociceptive, anti-inflammatory, antidiabetic, diuretic, inhibition of platelet aggregation, promotion of osteoblastic response, anti-leishmanial, and many other effects. The current review highlights the chemical constituents and pharmacological effects of Equisetum arvense.
{"title":"The pharmacology of Equisetum arvense- A review","authors":"A. Al-Snafi","doi":"10.9790/3013-0702013142","DOIUrl":"https://doi.org/10.9790/3013-0702013142","url":null,"abstract":"The previous studies revealed that Equisetum arvense contained alkaloids, carbohydrate, proteins and amino acids, phytosterols, saponins, sterols, ascorbic acid, silicic acid, phenol , tannin, flavonoids, triterpenoids, volatile oils and many other biological active constituents. The pharmacological studies showed that it possessed antioxidant, anticancer, antimicrobial, smooth muscle relaxant effects of the vessels and ileum, anticonvulsant, sedative, anti-anxiety, dermatological immunological, antinociceptive, anti-inflammatory, antidiabetic, diuretic, inhibition of platelet aggregation, promotion of osteoblastic response, anti-leishmanial, and many other effects. The current review highlights the chemical constituents and pharmacological effects of Equisetum arvense.","PeriodicalId":14540,"journal":{"name":"IOSR Journal of Pharmacy","volume":"5 1","pages":"31-42"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90507822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Previous studies showed that Dalbergia sissoo exerted antimicrobial, neural, cardiac, antioxidant, antiparasitic,antidiabetic,anti-inflammatory,analgesic, Osteogenic, dermatological, gastrointestinal, reproductive and many other effects. The current review highlights the chemical constituents and pharmacological effects of
{"title":"Chemical constituents and pharmacological effects of Dalbergia sissoo - A review","authors":"Ali Esmail Al-Snaf","doi":"10.9790/3013-0702015971","DOIUrl":"https://doi.org/10.9790/3013-0702015971","url":null,"abstract":"Previous studies showed that Dalbergia sissoo exerted antimicrobial, neural, cardiac, antioxidant, antiparasitic,antidiabetic,anti-inflammatory,analgesic, Osteogenic, dermatological, gastrointestinal, reproductive and many other effects. The current review highlights the chemical constituents and pharmacological effects of","PeriodicalId":14540,"journal":{"name":"IOSR Journal of Pharmacy","volume":"32 1","pages":"59-71"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87494164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shokouh Shayanpour, H. Shahbazian, Farshid Padyab, S. Baghaei, M. Zarei
1 Chronic Renal Failure Research Center, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. 2 MD, Internist, The director of Continued Medical Education, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. 3 Assistant professor, Department of Food Hygiene, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran. *Corresponding author: Farshid Padyab, Chronic Renal Failure Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Dr_padyab@yahoo.com
{"title":"Investigating effect of vitamin C on oxidative stress in patients undergoing chronic ambulatory peritoneal dialysis","authors":"Shokouh Shayanpour, H. Shahbazian, Farshid Padyab, S. Baghaei, M. Zarei","doi":"10.9790/3013-0706010911","DOIUrl":"https://doi.org/10.9790/3013-0706010911","url":null,"abstract":"1 Chronic Renal Failure Research Center, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. 2 MD, Internist, The director of Continued Medical Education, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. 3 Assistant professor, Department of Food Hygiene, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran. *Corresponding author: Farshid Padyab, Chronic Renal Failure Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Dr_padyab@yahoo.com","PeriodicalId":14540,"journal":{"name":"IOSR Journal of Pharmacy","volume":"150 3 1","pages":"09-11"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91132738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-06-01DOI: 10.9790/3013-070201111116
Oriana Boscolo, S. Flor, C. Dobrecky, Leandro Salvo, V. Tripodi, S. Lucangioli
{"title":"Development and validation of a LC-UV Method Applied to the Quality Control of Ursodeoxycholic Acid in Raw Material and Pharmaceutical Formulations","authors":"Oriana Boscolo, S. Flor, C. Dobrecky, Leandro Salvo, V. Tripodi, S. Lucangioli","doi":"10.9790/3013-070201111116","DOIUrl":"https://doi.org/10.9790/3013-070201111116","url":null,"abstract":"","PeriodicalId":14540,"journal":{"name":"IOSR Journal of Pharmacy","volume":"74 1","pages":"111-116"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84954853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Functional group analysis of Moringa concanensis Nimmo (Moringaceae) by FTIR spectrum","authors":"K. Santhi, R. Sengottuvel","doi":"10.9790/3013-0701012833","DOIUrl":"https://doi.org/10.9790/3013-0701012833","url":null,"abstract":"","PeriodicalId":14540,"journal":{"name":"IOSR Journal of Pharmacy","volume":"6 1","pages":"28-33"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84740596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A review on Dodonaea viscosa: A potential medicinal plant","authors":"A. Al-Snafi","doi":"10.9790/3013-0702011021","DOIUrl":"https://doi.org/10.9790/3013-0702011021","url":null,"abstract":"","PeriodicalId":14540,"journal":{"name":"IOSR Journal of Pharmacy","volume":"37 1","pages":"10-21"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84837618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
-Background:Blood borne diseases including viral hepatitis are important public health challenges worldwide. There is a notable dearth of data about Hepatitis B Virus (HBV), Hepatitis C Virus (HCV) and HIV prevalence in Afghanistan. The objective of this study was to estimate the seroprevalence of HBV, HCV, HIV infections among adult populations in Kandahar city, Afghanistan. Methods and Materials:A total of 1165 adult citizens in Kandahar city were included in the study using a cross-sectional design in October-November 2015. Data on demographic, socioeconomic and lifestyle factors were collected using WHO STEP wise approach. Rapid tests were conducted to identify the prevalence of HBV, HCV, and HIV infections. Statistical analysis performed Using SPSS v.20. Results: Of total records, females constituted almost half 597 (51.2%) with overall mean age of 38.3±11.2 years. The prevalence of HBV was 2% (22 out of 1153) for HBsAg on rapid test and 12 subject (1%) were seropositive for anti-HCV on rapid tests. None of subjects had co-infections. None of specimen were positive for HIV infection showed zero prevalence. Proportion of married groups was 79.3%, illiteracy rate was 73.2% and 88.5% of women were at home doing housework (housewives). About one tenth (9.7%) were smokers and 16.3% were snuffers. There was no statistical association of studied factors with HBV and HCV. Conclusion: The study found low prevalence of HBV and HCV in adult citizens in Kandahar city. Public awareness and health education regarding risk factors for viral hepatitis and encouragement for vaccination is recommended. More focus is needed to be given to high risk groups due their vulnerability to diseases.
{"title":"Burden of Hepatitis B, Hepatitis C and HIV Infections Among Adult Citizens in Kandahar City, Afghanistan","authors":"Khwaja Mir Islam SAEED","doi":"10.9790/3013-0701017885","DOIUrl":"https://doi.org/10.9790/3013-0701017885","url":null,"abstract":"-Background:Blood borne diseases including viral hepatitis are important public health challenges worldwide. There is a notable dearth of data about Hepatitis B Virus (HBV), Hepatitis C Virus (HCV) and HIV prevalence in Afghanistan. The objective of this study was to estimate the seroprevalence of HBV, HCV, HIV infections among adult populations in Kandahar city, Afghanistan. Methods and Materials:A total of 1165 adult citizens in Kandahar city were included in the study using a cross-sectional design in October-November 2015. Data on demographic, socioeconomic and lifestyle factors were collected using WHO STEP wise approach. Rapid tests were conducted to identify the prevalence of HBV, HCV, and HIV infections. Statistical analysis performed Using SPSS v.20. Results: Of total records, females constituted almost half 597 (51.2%) with overall mean age of 38.3±11.2 years. The prevalence of HBV was 2% (22 out of 1153) for HBsAg on rapid test and 12 subject (1%) were seropositive for anti-HCV on rapid tests. None of subjects had co-infections. None of specimen were positive for HIV infection showed zero prevalence. Proportion of married groups was 79.3%, illiteracy rate was 73.2% and 88.5% of women were at home doing housework (housewives). About one tenth (9.7%) were smokers and 16.3% were snuffers. There was no statistical association of studied factors with HBV and HCV. Conclusion: The study found low prevalence of HBV and HCV in adult citizens in Kandahar city. Public awareness and health education regarding risk factors for viral hepatitis and encouragement for vaccination is recommended. More focus is needed to be given to high risk groups due their vulnerability to diseases.","PeriodicalId":14540,"journal":{"name":"IOSR Journal of Pharmacy","volume":"27 1","pages":"78-85"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87777124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Motaş, D. Chiselita, N. Apreutesei, Vesna K. Hristova, T. Bonacci, M. Ahmad
The aim of the paper was the evaluation of the modifications of the retinal nerve fiber layer for the patients with primary open angle glaucoma or ocular hypertension associated with diabetes mellitus. Material and method: a prospective study that included a number of 25 patients. The study group was made up of 17 patients: 12 patients with primary open angle glaucoma (POAG) and diabetes mellitus and 5 patients with ocular hypertension (OH) and diabetes mellitus. The control group included 8 patients without glaucoma. All the patients with an accurate diagnosis of primary open angle glaucoma and intraocular hypertension that were medically and/or surgically treated or not, associated with diabetes mellitus, were included in the study. The patients with other types of glaucoma (closed angle, pigmentary, cortisone related, pseudoexfoliative), the ones without an accurate diagnosis of glaucoma or without associated diabetes mellitus were excluded. The control group was made up of subjects without a glaucoma diagnosis or clinical elements related to glaucoma, without surgical interventions in their medical records. All participants were evaluated with CIRRUS HD-OCT.
{"title":"Evolutionary Study of the Retinal Nerve Fiber Layer for the Patients with Glaucoma and Diabetes Mellitus","authors":"O. Motaş, D. Chiselita, N. Apreutesei, Vesna K. Hristova, T. Bonacci, M. Ahmad","doi":"10.9790/3013-0701013438","DOIUrl":"https://doi.org/10.9790/3013-0701013438","url":null,"abstract":"The aim of the paper was the evaluation of the modifications of the retinal nerve fiber layer for the patients with primary open angle glaucoma or ocular hypertension associated with diabetes mellitus. Material and method: a prospective study that included a number of 25 patients. The study group was made up of 17 patients: 12 patients with primary open angle glaucoma (POAG) and diabetes mellitus and 5 patients with ocular hypertension (OH) and diabetes mellitus. The control group included 8 patients without glaucoma. All the patients with an accurate diagnosis of primary open angle glaucoma and intraocular hypertension that were medically and/or surgically treated or not, associated with diabetes mellitus, were included in the study. The patients with other types of glaucoma (closed angle, pigmentary, cortisone related, pseudoexfoliative), the ones without an accurate diagnosis of glaucoma or without associated diabetes mellitus were excluded. The control group was made up of subjects without a glaucoma diagnosis or clinical elements related to glaucoma, without surgical interventions in their medical records. All participants were evaluated with CIRRUS HD-OCT.","PeriodicalId":14540,"journal":{"name":"IOSR Journal of Pharmacy","volume":"200 1","pages":"34-38"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76970695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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