Pub Date : 2021-10-25DOI: 10.30500/IVSA.2021.294603.1270
Emad Vakili, A. Najafpour
Objective- Testicular torsion and detorsion are significant clinical issues for infertile man. Torsion of the spermatic cord is an emergency condition resulting from rotation of the testis and epididymis around the axis of the spermatic cord. A rat testis model was used to assess effects of polyethylene glycol on ischemia-reperfusion injury. Design- Experimental study Animals- Twenty four healthy male Wistar rats Procedures- The rats were included and randomized into four investigational groups (n = 6): Group SHAM: Merely laparotomy was implemented. Group ISCHEMIA: Merely a 3- hour interval ischemia was done. Group IS/REP: A 3-hour interval ischemia, three-hour reperfusion for left testis, one week reperfusion for right testis were done and 20 µL normal saline was administered intraperitoneally (IP) 30 min before termination of ischemia. Group IS/REP/PEG: The same as group IS/REP as well as 20 µL PEG solution 3% (IP) 30 min before termination of ischemia. Evaluations were based on biochemical analyses and sperm parameters morphometry. Results- Polyethylene glycol enhanced antioxidant activity and quality of sperm parameters (p<0.05). Conclusion and clinical relevance-Polyethylene glycol could be helpful in minimizing ischemia-reperfusion injury in testicular tissue exposed to ischemia
{"title":"Effects of intraperitoneal administration of polyethylene glycol solution on ischemia-reperfusion injury in rat testicular torsion and detorsion model","authors":"Emad Vakili, A. Najafpour","doi":"10.30500/IVSA.2021.294603.1270","DOIUrl":"https://doi.org/10.30500/IVSA.2021.294603.1270","url":null,"abstract":"Objective- Testicular torsion and detorsion are significant clinical issues for infertile man. Torsion of the spermatic cord is an emergency condition resulting from rotation of the testis and epididymis around the axis of the spermatic cord. A rat testis model was used to assess effects of polyethylene glycol on ischemia-reperfusion injury. \u0000Design- Experimental study\u0000Animals- Twenty four healthy male Wistar rats\u0000Procedures- The rats were included and randomized into four investigational groups (n = 6): Group SHAM: Merely laparotomy was implemented. Group ISCHEMIA: Merely a 3- hour interval ischemia was done. Group IS/REP: A 3-hour interval ischemia, three-hour reperfusion for left testis, one week reperfusion for right testis were done and 20 µL normal saline was administered intraperitoneally (IP) 30 min before termination of ischemia. Group IS/REP/PEG: The same as group IS/REP as well as 20 µL PEG solution 3% (IP) 30 min before termination of ischemia. Evaluations were based on biochemical analyses and sperm parameters morphometry.\u0000Results- Polyethylene glycol enhanced antioxidant activity and quality of sperm parameters (p<0.05). \u0000Conclusion and clinical relevance-Polyethylene glycol could be helpful in minimizing ischemia-reperfusion injury in testicular tissue exposed to ischemia","PeriodicalId":14554,"journal":{"name":"Iranian Journal of Veterinary Surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45064445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-10-25DOI: 10.30500/IVSA.2021.294467.1269
Alihassan Ramezani, A. Najafpour, M. Farahpour
The objective was to evaluate the ability of cinnamon nanoparticles (CNPs) in the healing of wounds with Pseudomonas aeruginosa (PAE) infection as well as HAMLET sensitization in rats. Fifty healthy male Wistar rats were used in this study. The rats were divided into 5 groups (n=10), randomly. In the Normal group, no infected wounds were treated with a sterile solution of saline 0.9% (0.1 ml). In the PAE group, the wounds with Pseudomonas aeruginosa infection were only treated with a sterile solution of saline 0.9% (0.1 ml). In the PAE-HMLT group, HAMLET (100 µg) was used to treat infected wounds. In the PAE-CNM group, 1 mg/ml CNPs (0.1 ml) was applied topically to treat PAE-infected wounds. In the PAE-HMLT-CNM group, HAMLET (100 µg) and 1 mg/ml CNPs (0.1 ml) were applied topically to treat PAE-infected wounds. Microbiological examination, planimetric and biochemical showed significant differences between rats in the PAE-HMT-CNM group in comparison with other groups (p < 0.05). In conclusion, CNPs could offer potential to pay more attention to this harmless and easily available agent to be topically applied in wounds with infection.
{"title":"Effect of Cinnamon Nanoparticles in Presence of HAMLET on the Healing of Wounds Infected with Pseudomonas aeruginosa: An Animal Model Study","authors":"Alihassan Ramezani, A. Najafpour, M. Farahpour","doi":"10.30500/IVSA.2021.294467.1269","DOIUrl":"https://doi.org/10.30500/IVSA.2021.294467.1269","url":null,"abstract":"The objective was to evaluate the ability of cinnamon nanoparticles (CNPs) in the healing of wounds with Pseudomonas aeruginosa (PAE) infection as well as HAMLET sensitization in rats. Fifty healthy male Wistar rats were used in this study. The rats were divided into 5 groups (n=10), randomly. In the Normal group, no infected wounds were treated with a sterile solution of saline 0.9% (0.1 ml). In the PAE group, the wounds with Pseudomonas aeruginosa infection were only treated with a sterile solution of saline 0.9% (0.1 ml). In the PAE-HMLT group, HAMLET (100 µg) was used to treat infected wounds. In the PAE-CNM group, 1 mg/ml CNPs (0.1 ml) was applied topically to treat PAE-infected wounds. In the PAE-HMLT-CNM group, HAMLET (100 µg) and 1 mg/ml CNPs (0.1 ml) were applied topically to treat PAE-infected wounds. Microbiological examination, planimetric and biochemical showed significant differences between rats in the PAE-HMT-CNM group in comparison with other groups (p < 0.05). In conclusion, CNPs could offer potential to pay more attention to this harmless and easily available agent to be topically applied in wounds with infection.","PeriodicalId":14554,"journal":{"name":"Iranian Journal of Veterinary Surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47154495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-10-01DOI: 10.30500/IVSA.2021.273976.1251
Omid Abdi, V. Najarnezhad, V. Mohammadi
Blood transfusion is needed for the treatment of severe anemia. The purpose of this study was to detect clinical reactions, hematological and biochemical alterations after a blood transfusion from sheep to goat. Four Iranian mixed breed male sheep and goats were used in this study. Fifteen milliliters per kilogram of whole blood was taken from the sheep. Blood transfusion to goats was performed after 24 hours. Blood samples were taken from goats at times 0 (10 min before transfusion), 10 min, 3, 6, 12, 24, 48, 72, 96, and 192 hours after blood transfusion. No reactions such as coughing, dyspnea, muscle tremors, salivation, tearing, fever, and ruminal bloating during and after blood transfusion were seen. The respiratory rate significantly increased, 3, 6, and 12 hours after blood transfusion (p ˂ 0.05). Hematocrit was significantly reduced 3 hours after blood transfusion (p ˂ 0.05). Serum creatinine levels were increased significantly 10 minutes and 3 hours after blood transfusion (p ˂ 0.05). Blood urea serum was significantly increased 6 and 12 hours after blood transfusion (p ˂ 0.05). Serum calcium levels were increased significantly 72 and 96 hours after blood transfusion (p ˂ 0.05). Serum magnesium levels were significantly increased 72 and 96 hours after blood transfusion (p ˂ 0.05). In conclusion, temporary and transient changes observed in this study were safe and were not life-threatening for the goats, and the sheep blood can be used in anemic goats for one time.
{"title":"Evaluation of Clinical Signs, Hematological and Biochemical Parameters after Blood Transfusion from Sheep to Goat","authors":"Omid Abdi, V. Najarnezhad, V. Mohammadi","doi":"10.30500/IVSA.2021.273976.1251","DOIUrl":"https://doi.org/10.30500/IVSA.2021.273976.1251","url":null,"abstract":"Blood transfusion is needed for the treatment of severe anemia. The purpose of this study was to detect clinical reactions, hematological and biochemical alterations after a blood transfusion from sheep to goat. Four Iranian mixed breed male sheep and goats were used in this study. Fifteen milliliters per kilogram of whole blood was taken from the sheep. Blood transfusion to goats was performed after 24 hours. Blood samples were taken from goats at times 0 (10 min before transfusion), 10 min, 3, 6, 12, 24, 48, 72, 96, and 192 hours after blood transfusion. No reactions such as coughing, dyspnea, muscle tremors, salivation, tearing, fever, and ruminal bloating during and after blood transfusion were seen. The respiratory rate significantly increased, 3, 6, and 12 hours after blood transfusion (p ˂ 0.05). Hematocrit was significantly reduced 3 hours after blood transfusion (p ˂ 0.05). Serum creatinine levels were increased significantly 10 minutes and 3 hours after blood transfusion (p ˂ 0.05). Blood urea serum was significantly increased 6 and 12 hours after blood transfusion (p ˂ 0.05). Serum calcium levels were increased significantly 72 and 96 hours after blood transfusion (p ˂ 0.05). Serum magnesium levels were significantly increased 72 and 96 hours after blood transfusion (p ˂ 0.05). In conclusion, temporary and transient changes observed in this study were safe and were not life-threatening for the goats, and the sheep blood can be used in anemic goats for one time.","PeriodicalId":14554,"journal":{"name":"Iranian Journal of Veterinary Surgery","volume":"16 1","pages":"128-134"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46441227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-22DOI: 10.30500/IVSA.2021.287378.1260
Nagarajan Lakshmanan, Ramani Chandrasekara Iyer
Various degrees of entropion defects with redundant skin folds due to conformational defects are common in Chow Chow and Shar Pei breeds of dogs. The irritation caused by the eyelid and hairs on the conjunctiva results in lacrimation and blepharospasm. In severe cases, as the dogs reach 7-8 months of age the complications of this extreme entropion result in a corneal ulcer. Temporary tacking of the facial folds was resorted to augment the corneal healing and to assess the size of the skin to be removed later. Surgical excision of wrinkles - rhytidectomy was done as radical surgery and was found satisfactory. The area of natural tension lines along the wrinkles in the coronal region was marked before excision and for a good cosmetic outcome. This paper describes the need for a rhytidectomy -excision of large facial skin folds- in Chow Chow and Shar Pei breeds of dogs to correct bilateral superior total entropion
{"title":"Coronal Rhytidectomy for Correction of Bilateral Superior Entropion in Dogs with Redundant Eyebrow Droop - A Review of Two Cases","authors":"Nagarajan Lakshmanan, Ramani Chandrasekara Iyer","doi":"10.30500/IVSA.2021.287378.1260","DOIUrl":"https://doi.org/10.30500/IVSA.2021.287378.1260","url":null,"abstract":"Various degrees of entropion defects with redundant skin folds due to conformational defects are common in Chow Chow and Shar Pei breeds of dogs. The irritation caused by the eyelid and hairs on the conjunctiva results in lacrimation and blepharospasm. In severe cases, as the dogs reach 7-8 months of age the complications of this extreme entropion result in a corneal ulcer. Temporary tacking of the facial folds was resorted to augment the corneal healing and to assess the size of the skin to be removed later. Surgical excision of wrinkles - rhytidectomy was done as radical surgery and was found satisfactory. The area of natural tension lines along the wrinkles in the coronal region was marked before excision and for a good cosmetic outcome. This paper describes the need for a rhytidectomy -excision of large facial skin folds- in Chow Chow and Shar Pei breeds of dogs to correct bilateral superior total entropion","PeriodicalId":14554,"journal":{"name":"Iranian Journal of Veterinary Surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48427102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-09-13DOI: 10.30500/IVSA.2021.272528.1249
S. Muhammad
Cystosonography and cystography are among the appropriate imaging modalities employed in studying the morphological integrity of the urinary bladder in animals. Evaluation of the urinary bladder architecture following autologous composite colo-peritoneal pedicle grafts in the surgical repair of experimental urinary bladder defects was carried out in two dogs. The dorsal aspect of the urinary bladder served as the recipient site, while the seromuscular colonic pedicle flap of the descending colon along with free peritoneal sheath formed a composite tissue (donor tissue). Predetermined 2 cm x 4 cm dimension of urinary bladder defect was created on the dorsum of the urinary bladder and was patched with harvested 3 cm x 5 cm composite colo-peritoneal pedicle flap. All operations were aseptically and humanely conducted. The gross anatomical evaluation of the urinary bladder architecture was performed by ultrasonography and contrast radiography of the repaired urinary bladder. Post-surgical cystosonographic assessments on day 8 showed thickened urinary bladder wall at the point of the graft, which decreased markedly on day 21. Cystographic evaluation revealed gradual transition of the urinary bladder architecture at the point of the graft with clear delineation and minimal blurring at week 2 post-operation, which gradually disappeared at weeks 10 and 14. The cystosonographic and cystographic evaluations demonstrated evidence of advanced healing and well-preserved urinary bladder architecture with no evidence of leaks. The imaging modalities are adequately diagnostic to assess urinary bladder repairs following its management with composite colo-peritoneal graft in dogs.
膀胱超声和膀胱造影术是研究动物膀胱形态完整性的适当成像方式。对2只犬进行了自体复合结肠-腹膜蒂移植修复实验性膀胱缺损后膀胱结构的评价。膀胱背侧为受体部位，降结肠血清肌结肠蒂皮瓣与游离腹膜鞘形成复合组织(供体组织)。在膀胱背侧形成2 cm × 4 cm尺寸的膀胱缺损，取3 cm × 5 cm复合结肠-腹膜蒂皮瓣修补。所有的操作都是无菌和人道的。对修复后的膀胱进行超声和造影检查，对膀胱结构进行大体解剖评价。术后第8天膀胱超声检查显示移植物点膀胱壁增厚，第21天明显减少。膀胱造影检查显示，术后2周移植物点膀胱结构逐渐转变，轮廓清晰，模糊程度最小，10周和14周逐渐消失。膀胱超声和膀胱造影检查显示膀胱愈合良好，膀胱结构保存完好，无渗漏。在犬的复合结肠-腹膜移植后，成像方式对评估膀胱修复有充分的诊断价值。
{"title":"Ultrasonographic and Cystographic Evaluations of Urinary Bladder Defects Managed with Composite Colo-Peritoneal Grafts in Dogs","authors":"S. Muhammad","doi":"10.30500/IVSA.2021.272528.1249","DOIUrl":"https://doi.org/10.30500/IVSA.2021.272528.1249","url":null,"abstract":"Cystosonography and cystography are among the appropriate imaging modalities employed in studying the morphological integrity of the urinary bladder in animals. Evaluation of the urinary bladder architecture following autologous composite colo-peritoneal pedicle grafts in the surgical repair of experimental urinary bladder defects was carried out in two dogs. The dorsal aspect of the urinary bladder served as the recipient site, while the seromuscular colonic pedicle flap of the descending colon along with free peritoneal sheath formed a composite tissue (donor tissue). Predetermined 2 cm x 4 cm dimension of urinary bladder defect was created on the dorsum of the urinary bladder and was patched with harvested 3 cm x 5 cm composite colo-peritoneal pedicle flap. All operations were aseptically and humanely conducted. The gross anatomical evaluation of the urinary bladder architecture was performed by ultrasonography and contrast radiography of the repaired urinary bladder. Post-surgical cystosonographic assessments on day 8 showed thickened urinary bladder wall at the point of the graft, which decreased markedly on day 21. Cystographic evaluation revealed gradual transition of the urinary bladder architecture at the point of the graft with clear delineation and minimal blurring at week 2 post-operation, which gradually disappeared at weeks 10 and 14. The cystosonographic and cystographic evaluations demonstrated evidence of advanced healing and well-preserved urinary bladder architecture with no evidence of leaks. The imaging modalities are adequately diagnostic to assess urinary bladder repairs following its management with composite colo-peritoneal graft in dogs.","PeriodicalId":14554,"journal":{"name":"Iranian Journal of Veterinary Surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48117139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-28DOI: 10.30500/IVSA.2021.287911.1262
Salar Ghanbari, Aboutorab Tabatabaei-Naeini, Alireza Raayat-Jahromi, M. Amini
The purpose of this study is to evaluate the effects of gastric bypass surgery and sleeve gastrectomy on vitamin B12 values in dogs. Gastric dilation and volvulus (GDV) is an acute disease with a high mortality rate in dogs. Either gastric bypass surgery or sleeve gastrectomy can be utilized as surgical treatments for GDV. These techniques can provide increased success and fewer complications, however, one undesirable outcome can be vitamin B12 insufficiency. Three groups of dogs received gastric surgeries, one group underwent gastric rotation and derotation with no tissue gastric incisions, the two other groups had gastric bypass surgery and sleeve gastrectomy. Vitamin B12 level was evaluated two weeks prior to surgery, at the time of surgery, two, four, and six weeks after surgery. The results demonstrated no inter-group differences two weeks prior to surgery until four weeks after surgery. However, six weeks post-operation, significant differences between the sleeve gastrectomy group, and the other two groups were shown in vitamin B12 levels. Gastric bypass surgery and sleeve gastrectomy can both be utilized as new surgical managements of GDV. However, as we have demonstrated in this article, an important expected side effect is vitamin B12 insufficiency, in dogs that receive sleeve gastrectomy for GDV treatment. This necessary element must be substituted artificially for all dogs which had received these surgical managements.
{"title":"Evaluating the Effects of Gastric By-Pass Surgery and Sleeve Gastrectomy, as New GDV Treatment Modalities, on Vitamin B12 Values in Dogs’","authors":"Salar Ghanbari, Aboutorab Tabatabaei-Naeini, Alireza Raayat-Jahromi, M. Amini","doi":"10.30500/IVSA.2021.287911.1262","DOIUrl":"https://doi.org/10.30500/IVSA.2021.287911.1262","url":null,"abstract":"The purpose of this study is to evaluate the effects of gastric bypass surgery and sleeve gastrectomy on vitamin B12 values in dogs. Gastric dilation and volvulus (GDV) is an acute disease with a high mortality rate in dogs. Either gastric bypass surgery or sleeve gastrectomy can be utilized as surgical treatments for GDV. These techniques can provide increased success and fewer complications, however, one undesirable outcome can be vitamin B12 insufficiency. Three groups of dogs received gastric surgeries, one group underwent gastric rotation and derotation with no tissue gastric incisions, the two other groups had gastric bypass surgery and sleeve gastrectomy. Vitamin B12 level was evaluated two weeks prior to surgery, at the time of surgery, two, four, and six weeks after surgery. The results demonstrated no inter-group differences two weeks prior to surgery until four weeks after surgery. However, six weeks post-operation, significant differences between the sleeve gastrectomy group, and the other two groups were shown in vitamin B12 levels. Gastric bypass surgery and sleeve gastrectomy can both be utilized as new surgical managements of GDV. However, as we have demonstrated in this article, an important expected side effect is vitamin B12 insufficiency, in dogs that receive sleeve gastrectomy for GDV treatment. This necessary element must be substituted artificially for all dogs which had received these surgical managements.","PeriodicalId":14554,"journal":{"name":"Iranian Journal of Veterinary Surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48083431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-28DOI: 10.30500/IVSA.2021.289128.1264
Neda Erfani, S. Kazemi-Darabadi, S. Hashemi-Asl, A. Shahbazfar
Enthesis joins tendon, ligament, or joint capsule to the bone, which are two very different tissues. As a result, it is more prone to stress and increased risk of rupture. The purposes of this study were to evaluate the role of limb movement or immobilization in enthesis healing after surgical repair and found out if radiography could be a reliable method for determining its prognosis. Fourteen New Zealand white rabbits were randomly divided into two groups. After detaching the Achilles tendon from the bone surface, the tendon was re-attached to the bone with a modified Kessler suture pattern. The limb of group 1 rabbits was externally fixed with the fiberglass cast. In group 2, however, no cast was used. Radiographs were taken after surgery and in weeks 2, 4, 6, and 8 post-operation. Samples were taken from the area after 8 weeks and stained by the hematoxylin-eosin method. The results were reported descriptively. Bone growth, increased chondrocytes in the cartilaginous region, and increased fibroblasts and fibrocytes were seen in group 1. While erosion, collagen fibers regularity, and tissue maturity were more predominant in group 2. Although early limb movement during the enthesis healing period helps to increase the regularity of collagen fibers in the tendinous zone of the enthesis, it does not increase the amount of callus in the bone and increases the risk of bone erosions and even fractures. While stabilizing the limb in the first two months of enthesis healing protects the bone against the forces and helps bone formation, which has a positive role in healing the enthesis.
{"title":"Radiographic and Histopathologic Evidences of Movement versus Immobilization Effects on Enthesis Formation in Rabbits","authors":"Neda Erfani, S. Kazemi-Darabadi, S. Hashemi-Asl, A. Shahbazfar","doi":"10.30500/IVSA.2021.289128.1264","DOIUrl":"https://doi.org/10.30500/IVSA.2021.289128.1264","url":null,"abstract":"Enthesis joins tendon, ligament, or joint capsule to the bone, which are two very different tissues. As a result, it is more prone to stress and increased risk of rupture. The purposes of this study were to evaluate the role of limb movement or immobilization in enthesis healing after surgical repair and found out if radiography could be a reliable method for determining its prognosis. Fourteen New Zealand white rabbits were randomly divided into two groups. After detaching the Achilles tendon from the bone surface, the tendon was re-attached to the bone with a modified Kessler suture pattern. The limb of group 1 rabbits was externally fixed with the fiberglass cast. In group 2, however, no cast was used. Radiographs were taken after surgery and in weeks 2, 4, 6, and 8 post-operation. Samples were taken from the area after 8 weeks and stained by the hematoxylin-eosin method. The results were reported descriptively. Bone growth, increased chondrocytes in the cartilaginous region, and increased fibroblasts and fibrocytes were seen in group 1. While erosion, collagen fibers regularity, and tissue maturity were more predominant in group 2. Although early limb movement during the enthesis healing period helps to increase the regularity of collagen fibers in the tendinous zone of the enthesis, it does not increase the amount of callus in the bone and increases the risk of bone erosions and even fractures. While stabilizing the limb in the first two months of enthesis healing protects the bone against the forces and helps bone formation, which has a positive role in healing the enthesis.","PeriodicalId":14554,"journal":{"name":"Iranian Journal of Veterinary Surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41588902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-23DOI: 10.30500/IVSA.2021.296292.1273
Zahra Noori, S. Ghasemi, A. Mirshahi, Mehdad Mohri, A. Mohamadnia
This study is designed to examine biochemical (serum amyloid A (SAA), haptoglobin (Hp) and D-dimer) and cytological (total nucleated cell count (TNCC), neutrophil, lymphocyte, and monocyte count) characteristics of serum and synovial fluid of the equine DFTS. Twenty-eight adult horses of different breeds were used in this study. Synovial fluid samples were aseptically collected in EDTA from 43 limbs in 20 horses with (study group) and 8 limbs in 8 horses without (control group) distention of DFTS. Lymphocyte, monocyte, neutrophil, and TNCC in the synovial fluid were statistically higher in the distended sheath that shows an inflammatory nature of the distention, however, concentrations of D-dimer was lower in serum (0.1, 0.10 - 3.80) & (0.2, 0.10 - 0.20) than synovial fluid (19.2, 17.78 - 20.00) & (20, 19.90 - 20.00)) in both groups. The serum SAA concentrations of the control group (1.7, 0.10- 2.16) were significantly higher than the study group (1, 0.86 - 1.05) and the concentration of SAA in serum was higher than synovial fluid (0.89, 0.86 - 0.98) in the control group. Results of this current study show that a cytological evaluation of the synovial fluid is more valuable than biochemical findings in the diagnosis of the inflammatory nature of this condition.
{"title":"Comparison of Synovial Fluid Composition in Distended and Normal Digital Flexor Tendon Sheath (DFTS) of Horses: A Pilot Study","authors":"Zahra Noori, S. Ghasemi, A. Mirshahi, Mehdad Mohri, A. Mohamadnia","doi":"10.30500/IVSA.2021.296292.1273","DOIUrl":"https://doi.org/10.30500/IVSA.2021.296292.1273","url":null,"abstract":"This study is designed to examine biochemical (serum amyloid A (SAA), haptoglobin (Hp) and D-dimer) and cytological (total nucleated cell count (TNCC), neutrophil, lymphocyte, and monocyte count) characteristics of serum and synovial fluid of the equine DFTS. Twenty-eight adult horses of different breeds were used in this study. Synovial fluid samples were aseptically collected in EDTA from 43 limbs in 20 horses with (study group) and 8 limbs in 8 horses without (control group) distention of DFTS. Lymphocyte, monocyte, neutrophil, and TNCC in the synovial fluid were statistically higher in the distended sheath that shows an inflammatory nature of the distention, however, concentrations of D-dimer was lower in serum (0.1, 0.10 - 3.80) & (0.2, 0.10 - 0.20) than synovial fluid (19.2, 17.78 - 20.00) & (20, 19.90 - 20.00)) in both groups. The serum SAA concentrations of the control group (1.7, 0.10- 2.16) were significantly higher than the study group (1, 0.86 - 1.05) and the concentration of SAA in serum was higher than synovial fluid (0.89, 0.86 - 0.98) in the control group. Results of this current study show that a cytological evaluation of the synovial fluid is more valuable than biochemical findings in the diagnosis of the inflammatory nature of this condition.","PeriodicalId":14554,"journal":{"name":"Iranian Journal of Veterinary Surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42228488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-23DOI: 10.30500/IVSA.2021.292376.1268
M. Shahraki, M. Molaei, R. Kheirandish, Pourya Mohammadi, E. Sakhaee
The present study was conducted to evaluate the wound healing effects of liposome nanocarrier containing Scrophularia striata extract. Seventy-two male Wistar albino rats were divided into 6 groups of 12 animals each. Rats were anesthetized, and dorsum shaved. A 100 g cylindrical copper rod of 1cm diameter was heated up to 100°C. It was placed on the skin without any pressure. Histopathological evaluation and the macroscopic size processing and analysis of the burn were employed to study the potential of wound healing in study groups. The study groups were: Positive control group (Zinc oxide treatment), treatment group (Ointment containing nanoliposomes loaded with extract Scrophularia striata), extract group (Ointment containing hydroalcoholic extract Scrophularia striata), control group of nanoliposomes (Ointment containing Nano liposomes), Eucerin control group (Ointment containing Eucerin), negative control group (No treatment). On the 5th, 10th, and 15th days after the initial operation, samples were taken from 4 rats of each group. The results showed that loaded nanoliposomes had a nanometric size and spherical morphology. Also, the wound size of the treatment group was smaller than other groups and had the best effect on repairing wound healing. Also, in other groups, positive control had a better effect on wound repair than extract, Eucerin, nano, and negative groups. According to the highest re-epithelialization, granulation tissue formation, and the lowest necrotic tissue, we could suggest that the treatment group had the best healing effect among other groups.
{"title":"The Effect of Liposome Nanocarrier Containing Scrophularia striata Extract on Burn Wound Healing in Rats","authors":"M. Shahraki, M. Molaei, R. Kheirandish, Pourya Mohammadi, E. Sakhaee","doi":"10.30500/IVSA.2021.292376.1268","DOIUrl":"https://doi.org/10.30500/IVSA.2021.292376.1268","url":null,"abstract":"The present study was conducted to evaluate the wound healing effects of liposome nanocarrier containing Scrophularia striata extract. Seventy-two male Wistar albino rats were divided into 6 groups of 12 animals each. Rats were anesthetized, and dorsum shaved. A 100 g cylindrical copper rod of 1cm diameter was heated up to 100°C. It was placed on the skin without any pressure. Histopathological evaluation and the macroscopic size processing and analysis of the burn were employed to study the potential of wound healing in study groups. The study groups were: Positive control group (Zinc oxide treatment), treatment group (Ointment containing nanoliposomes loaded with extract Scrophularia striata), extract group (Ointment containing hydroalcoholic extract Scrophularia striata), control group of nanoliposomes (Ointment containing Nano liposomes), Eucerin control group (Ointment containing Eucerin), negative control group (No treatment). On the 5th, 10th, and 15th days after the initial operation, samples were taken from 4 rats of each group. The results showed that loaded nanoliposomes had a nanometric size and spherical morphology. Also, the wound size of the treatment group was smaller than other groups and had the best effect on repairing wound healing. Also, in other groups, positive control had a better effect on wound repair than extract, Eucerin, nano, and negative groups. According to the highest re-epithelialization, granulation tissue formation, and the lowest necrotic tissue, we could suggest that the treatment group had the best healing effect among other groups.","PeriodicalId":14554,"journal":{"name":"Iranian Journal of Veterinary Surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44451762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-12DOI: 10.30500/IVSA.2021.286032.1258
M. Javdani, A. Aali, A. Mohebi, F. Heydarpour, A. Bigham-Sadegh
With regard to the importance of prescribing medicinal plants in the traditional veterinary medicine and the anti-inflammatory role of ginger, the current study was conducted to evaluate the effects of the oral administration of the ginger rhizome powder following OHE in puppies. Ten healthy young female puppies were randomly assigned to two equal groups, a control and an experimental group. Two hours before surgical neutering by ovariohysterectomy, a Zintoma Capsule (Zingiber officinale) was administered orally in the experimental group and continued daily for 10 days after surgery. Several inflammatory markers were measured to evaluate the postsurgical status of the animals in the different times. Although there was no difference in the albumin and glucose level between the experimental and control groups at the different times, but a statistically significant reduction in the inflammatory markers CRP, fibrinogen, TNF-α, and IL-6 was observed in the experimental group compared to the control group. These preliminary findings suggest the usefulness of ginger rhizome powder, a traditional herbal dietary supplement, in the reduction of postoperative inflammatory reactions in dogs undergoing ovariohysterectomy.
{"title":"Oral Administration of Ginger Rhizome Powder and Postoperative Inflammation Indices in Ovariohysterectomized Dogs","authors":"M. Javdani, A. Aali, A. Mohebi, F. Heydarpour, A. Bigham-Sadegh","doi":"10.30500/IVSA.2021.286032.1258","DOIUrl":"https://doi.org/10.30500/IVSA.2021.286032.1258","url":null,"abstract":"With regard to the importance of prescribing medicinal plants in the traditional veterinary medicine and the anti-inflammatory role of ginger, the current study was conducted to evaluate the effects of the oral administration of the ginger rhizome powder following OHE in puppies. Ten healthy young female puppies were randomly assigned to two equal groups, a control and an experimental group. Two hours before surgical neutering by ovariohysterectomy, a Zintoma Capsule (Zingiber officinale) was administered orally in the experimental group and continued daily for 10 days after surgery. Several inflammatory markers were measured to evaluate the postsurgical status of the animals in the different times. Although there was no difference in the albumin and glucose level between the experimental and control groups at the different times, but a statistically significant reduction in the inflammatory markers CRP, fibrinogen, TNF-α, and IL-6 was observed in the experimental group compared to the control group. These preliminary findings suggest the usefulness of ginger rhizome powder, a traditional herbal dietary supplement, in the reduction of postoperative inflammatory reactions in dogs undergoing ovariohysterectomy.","PeriodicalId":14554,"journal":{"name":"Iranian Journal of Veterinary Surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45251348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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